FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1390, 469 aa
1>>>pF1KA1390 469 - 469 aa - 469 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.6259+/-0.000775; mu= 7.9957+/- 0.047
mean_var=133.2733+/-27.005, 0's: 0 Z-trim(113.3): 16 B-trim: 214 in 1/51
Lambda= 0.111097
statistics sampled from 13971 (13981) to 13971 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.768), E-opt: 0.2 (0.429), width: 16
Scan time: 3.420
The best scores are: opt bits E(32554)
CCDS976.1 FAM63A gene_id:55793|Hs108|chr1 ( 469) 3194 522.9 2.7e-148
CCDS53361.1 FAM63A gene_id:55793|Hs108|chr1 ( 517) 3194 523.0 3e-148
CCDS55635.1 FAM63A gene_id:55793|Hs108|chr1 ( 374) 2534 417.1 1.6e-116
CCDS30854.1 FAM63A gene_id:55793|Hs108|chr1 ( 327) 2180 360.3 1.7e-99
CCDS42046.1 FAM63B gene_id:54629|Hs108|chr15 ( 621) 1419 238.5 1.5e-62
CCDS45268.1 FAM63B gene_id:54629|Hs108|chr15 ( 620) 1409 236.9 4.6e-62
>>CCDS976.1 FAM63A gene_id:55793|Hs108|chr1 (469 aa)
initn: 3194 init1: 3194 opt: 3194 Z-score: 2775.7 bits: 522.9 E(32554): 2.7e-148
Smith-Waterman score: 3194; 99.8% identity (99.8% similar) in 469 aa overlap (1-469:1-469)
10 20 30 40 50 60
pF1KA1 MEYHQPEDPAPGKAGTAEAVIPENHEVLAGPDEHPQDTDARDADGEAREREPADQALLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS97 MEYHQPEDPAPGKAGTAEAVIPENHEVLAGPDEHPQDTDARDADGEAREREPADQALLPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 QCGDNLESPLPEASSAPPGPTLGTLPEVETIRACSMPQELPQSPRTRQPEPDFYCVKWIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS97 QCGDNLESPLPEASSAPPGPTLGTLPEVETIRACSMPQELPQSPRTRQPEPDFYCVKWIP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 WKGEQTPIITQSTNGPCPLLAIMNILFLQWKVKLPPQKEVITSDELMAHLGNCLLSIKPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS97 WKGEQTPIITQSTNGPCPLLAIMNILFLQWKVKLPPQKEVITSDELMAHLGNCLLSIKPQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 EKSEGLQLNFQQNVDDAMTVLPKLATGLDVNVRFTGVSDFEYTPECSVFDLLGIPLYHGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS97 EKSEGLQLNFQQNVDDAMTVLPKLATGLDVNVRFTGVSDFEYTPECSVFDLLGIPLYHGW
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 LVDPQSPEAVRAVGKLSYNQLVERIITCKHSSDTNLVTEGLIAEQFLETTAAQLTYHGLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS97 LVDPQSPEAVRAVGKLSYNQLVERIITCKHSSDTNLVTEGLIAEQFLETTAAQLTYHGLC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 ELTAAAKEGELSVFFRNNHFSTMTKHKSHLYLLVTDQGFLQEEQVVWESLHNVDGDSCFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS97 ELTAAAKEGELSVFFRNNHFSTMTKHKSHLYLLVTDQGFLQEEQVVWESLHNVDGDSCFC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 DSDFHLSHSLGKGPGAEGGSGSPEKQLQVDQDYLIALSLQQQQPRGPLGLTDLELAQQLQ
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
CCDS97 DSDFHLSHSLGKGPGAEGGSGSPETQLQVDQDYLIALSLQQQQPRGPLGLTDLELAQQLQ
370 380 390 400 410 420
430 440 450 460
pF1KA1 QEEYQQQQAAQPVRMRTRVLSLQGRGATSGRPAGERRQRPKHESDCILL
:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS97 QEEYQQQQAAQPVRMRTRVLSLQGRGATSGRPAGERRQRPKHESDCILL
430 440 450 460
>>CCDS53361.1 FAM63A gene_id:55793|Hs108|chr1 (517 aa)
initn: 3194 init1: 3194 opt: 3194 Z-score: 2775.1 bits: 523.0 E(32554): 3e-148
Smith-Waterman score: 3194; 99.8% identity (99.8% similar) in 469 aa overlap (1-469:49-517)
10 20 30
pF1KA1 MEYHQPEDPAPGKAGTAEAVIPENHEVLAG
::::::::::::::::::::::::::::::
CCDS53 CHSFASQAWLRQVPEVSKHLQCPSAKSLLTMEYHQPEDPAPGKAGTAEAVIPENHEVLAG
20 30 40 50 60 70
40 50 60 70 80 90
pF1KA1 PDEHPQDTDARDADGEAREREPADQALLPSQCGDNLESPLPEASSAPPGPTLGTLPEVET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 PDEHPQDTDARDADGEAREREPADQALLPSQCGDNLESPLPEASSAPPGPTLGTLPEVET
80 90 100 110 120 130
100 110 120 130 140 150
pF1KA1 IRACSMPQELPQSPRTRQPEPDFYCVKWIPWKGEQTPIITQSTNGPCPLLAIMNILFLQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 IRACSMPQELPQSPRTRQPEPDFYCVKWIPWKGEQTPIITQSTNGPCPLLAIMNILFLQW
140 150 160 170 180 190
160 170 180 190 200 210
pF1KA1 KVKLPPQKEVITSDELMAHLGNCLLSIKPQEKSEGLQLNFQQNVDDAMTVLPKLATGLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 KVKLPPQKEVITSDELMAHLGNCLLSIKPQEKSEGLQLNFQQNVDDAMTVLPKLATGLDV
200 210 220 230 240 250
220 230 240 250 260 270
pF1KA1 NVRFTGVSDFEYTPECSVFDLLGIPLYHGWLVDPQSPEAVRAVGKLSYNQLVERIITCKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 NVRFTGVSDFEYTPECSVFDLLGIPLYHGWLVDPQSPEAVRAVGKLSYNQLVERIITCKH
260 270 280 290 300 310
280 290 300 310 320 330
pF1KA1 SSDTNLVTEGLIAEQFLETTAAQLTYHGLCELTAAAKEGELSVFFRNNHFSTMTKHKSHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 SSDTNLVTEGLIAEQFLETTAAQLTYHGLCELTAAAKEGELSVFFRNNHFSTMTKHKSHL
320 330 340 350 360 370
340 350 360 370 380 390
pF1KA1 YLLVTDQGFLQEEQVVWESLHNVDGDSCFCDSDFHLSHSLGKGPGAEGGSGSPEKQLQVD
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
CCDS53 YLLVTDQGFLQEEQVVWESLHNVDGDSCFCDSDFHLSHSLGKGPGAEGGSGSPETQLQVD
380 390 400 410 420 430
400 410 420 430 440 450
pF1KA1 QDYLIALSLQQQQPRGPLGLTDLELAQQLQQEEYQQQQAAQPVRMRTRVLSLQGRGATSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 QDYLIALSLQQQQPRGPLGLTDLELAQQLQQEEYQQQQAAQPVRMRTRVLSLQGRGATSG
440 450 460 470 480 490
460
pF1KA1 RPAGERRQRPKHESDCILL
:::::::::::::::::::
CCDS53 RPAGERRQRPKHESDCILL
500 510
>>CCDS55635.1 FAM63A gene_id:55793|Hs108|chr1 (374 aa)
initn: 2534 init1: 2534 opt: 2534 Z-score: 2205.5 bits: 417.1 E(32554): 1.6e-116
Smith-Waterman score: 2534; 99.7% identity (99.7% similar) in 374 aa overlap (96-469:1-374)
70 80 90 100 110 120
pF1KA1 LESPLPEASSAPPGPTLGTLPEVETIRACSMPQELPQSPRTRQPEPDFYCVKWIPWKGEQ
::::::::::::::::::::::::::::::
CCDS55 MPQELPQSPRTRQPEPDFYCVKWIPWKGEQ
10 20 30
130 140 150 160 170 180
pF1KA1 TPIITQSTNGPCPLLAIMNILFLQWKVKLPPQKEVITSDELMAHLGNCLLSIKPQEKSEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 TPIITQSTNGPCPLLAIMNILFLQWKVKLPPQKEVITSDELMAHLGNCLLSIKPQEKSEG
40 50 60 70 80 90
190 200 210 220 230 240
pF1KA1 LQLNFQQNVDDAMTVLPKLATGLDVNVRFTGVSDFEYTPECSVFDLLGIPLYHGWLVDPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 LQLNFQQNVDDAMTVLPKLATGLDVNVRFTGVSDFEYTPECSVFDLLGIPLYHGWLVDPQ
100 110 120 130 140 150
250 260 270 280 290 300
pF1KA1 SPEAVRAVGKLSYNQLVERIITCKHSSDTNLVTEGLIAEQFLETTAAQLTYHGLCELTAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 SPEAVRAVGKLSYNQLVERIITCKHSSDTNLVTEGLIAEQFLETTAAQLTYHGLCELTAA
160 170 180 190 200 210
310 320 330 340 350 360
pF1KA1 AKEGELSVFFRNNHFSTMTKHKSHLYLLVTDQGFLQEEQVVWESLHNVDGDSCFCDSDFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 AKEGELSVFFRNNHFSTMTKHKSHLYLLVTDQGFLQEEQVVWESLHNVDGDSCFCDSDFH
220 230 240 250 260 270
370 380 390 400 410 420
pF1KA1 LSHSLGKGPGAEGGSGSPEKQLQVDQDYLIALSLQQQQPRGPLGLTDLELAQQLQQEEYQ
::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
CCDS55 LSHSLGKGPGAEGGSGSPETQLQVDQDYLIALSLQQQQPRGPLGLTDLELAQQLQQEEYQ
280 290 300 310 320 330
430 440 450 460
pF1KA1 QQQAAQPVRMRTRVLSLQGRGATSGRPAGERRQRPKHESDCILL
::::::::::::::::::::::::::::::::::::::::::::
CCDS55 QQQAAQPVRMRTRVLSLQGRGATSGRPAGERRQRPKHESDCILL
340 350 360 370
>>CCDS30854.1 FAM63A gene_id:55793|Hs108|chr1 (327 aa)
initn: 2180 init1: 2180 opt: 2180 Z-score: 1899.8 bits: 360.3 E(32554): 1.7e-99
Smith-Waterman score: 2180; 99.7% identity (99.7% similar) in 327 aa overlap (143-469:1-327)
120 130 140 150 160 170
pF1KA1 FYCVKWIPWKGEQTPIITQSTNGPCPLLAIMNILFLQWKVKLPPQKEVITSDELMAHLGN
::::::::::::::::::::::::::::::
CCDS30 MNILFLQWKVKLPPQKEVITSDELMAHLGN
10 20 30
180 190 200 210 220 230
pF1KA1 CLLSIKPQEKSEGLQLNFQQNVDDAMTVLPKLATGLDVNVRFTGVSDFEYTPECSVFDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 CLLSIKPQEKSEGLQLNFQQNVDDAMTVLPKLATGLDVNVRFTGVSDFEYTPECSVFDLL
40 50 60 70 80 90
240 250 260 270 280 290
pF1KA1 GIPLYHGWLVDPQSPEAVRAVGKLSYNQLVERIITCKHSSDTNLVTEGLIAEQFLETTAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 GIPLYHGWLVDPQSPEAVRAVGKLSYNQLVERIITCKHSSDTNLVTEGLIAEQFLETTAA
100 110 120 130 140 150
300 310 320 330 340 350
pF1KA1 QLTYHGLCELTAAAKEGELSVFFRNNHFSTMTKHKSHLYLLVTDQGFLQEEQVVWESLHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 QLTYHGLCELTAAAKEGELSVFFRNNHFSTMTKHKSHLYLLVTDQGFLQEEQVVWESLHN
160 170 180 190 200 210
360 370 380 390 400 410
pF1KA1 VDGDSCFCDSDFHLSHSLGKGPGAEGGSGSPEKQLQVDQDYLIALSLQQQQPRGPLGLTD
:::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
CCDS30 VDGDSCFCDSDFHLSHSLGKGPGAEGGSGSPETQLQVDQDYLIALSLQQQQPRGPLGLTD
220 230 240 250 260 270
420 430 440 450 460
pF1KA1 LELAQQLQQEEYQQQQAAQPVRMRTRVLSLQGRGATSGRPAGERRQRPKHESDCILL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 LELAQQLQQEEYQQQQAAQPVRMRTRVLSLQGRGATSGRPAGERRQRPKHESDCILL
280 290 300 310 320
>>CCDS42046.1 FAM63B gene_id:54629|Hs108|chr15 (621 aa)
initn: 1414 init1: 1253 opt: 1419 Z-score: 1236.3 bits: 238.5 E(32554): 1.5e-62
Smith-Waterman score: 1442; 54.5% identity (74.6% similar) in 433 aa overlap (58-465:185-608)
30 40 50 60 70 80
pF1KA1 LAGPDEHPQDTDARDADGEAREREPADQALLPSQCGDN----LESPLPEAS-SAPPGPTL
.::.: : :. .:: .: :
CCDS42 GGLSSSCSDPSPPGESPSLDSLESFSNLHSFPSSCEFNSEEGAENRVPEEEEGAAVLP--
160 170 180 190 200 210
90 100 110 120 130 140
pF1KA1 GTLPEVETIRACSMPQELPQSPRTRQPEPDFYCVKWIPWKGEQTPIITQSTNGPCPLLAI
:..: . .. : : : . : : . : .::: :: :.::::::. :::::::::
CCDS42 GAVPLCKEEEGEETAQVLAAS-KERFPGQSVYHIKWIQWKEENTPIITQNENGPCPLLAI
220 230 240 250 260 270
150 160 170 180 190 200
pF1KA1 MNILFLQWKVKLPPQKEVITSDELMAHLGNCLLSIKPQEKSEGLQLNFQQNVDDAMTVLP
.:.:.: :::::::. :.::...:: .::. .:. ::.: :: .::..::..:::..:
CCDS42 LNVLLLAWKVKLPPMMEIITAEQLMEYLGDYMLDAKPKEISEIQRLNYEQNMSDAMAILH
280 290 300 310 320 330
210 220 230 240 250 260
pF1KA1 KLATGLDVNVRFTGVSDFEYTPECSVFDLLGIPLYHGWLVDPQSPEAVRAVGKLSYNQLV
:: :::::::::::: ::::::: ::::: :::::::::::: . :.:::. ::::::
CCDS42 KLQTGLDVNVRFTGVRVFEYTPECIVFDLLDIPLYHGWLVDPQIDDIVKAVGNCSYNQLV
340 350 360 370 380 390
270 280 290 300 310 320
pF1KA1 ERIITCKHSSDTNLVTEGLIAEQFLETTAAQLTYHGLCELTAAAKEGELSVFFRNNHFST
:.::.::.:....::.::..:::::..::.:::::::::::....:::: ::::::::::
CCDS42 EKIISCKQSDNSELVSEGFVAEQFLNNTATQLTYHGLCELTSTVQEGELCVFFRNNHFST
400 410 420 430 440 450
330 340 350 360 370 380
pF1KA1 MTKHKSHLYLLVTDQGFLQEEQVVWESLHNVDGDSCFCDSDFHLSHSLGKGPGAEGGSGS
:::.:..::::::::::: ::.::::::::::::. ::::.::: : .. .
CCDS42 MTKYKGQLYLLVTDQGFLTEEKVVWESLHNVDGDGNFCDSEFHLR------PPSDPETVY
460 470 480 490 500
390 400 410 420
pF1KA1 PEKQLQVDQDYLIALSLQQQQPRG-------PLGLTDLELAQQLQQEE-------YQQQQ
.: :.:::::.::::::.: : :..:::::..::.:: ::.:.
CCDS42 KGQQDQIDQDYLMALSLQQEQQSQEINWEQIPEGISDLELAKKLQEEEDRRASQYYQEQE
510 520 530 540 550 560
430 440 450 460
pF1KA1 AAQPVRMRTRVLSLQGRGA----TSGRPAG--ERRQRPKHESDCILL
: . . . . ::. : .::: .: ::... .:.:
CCDS42 QAAAAAAAASTQAQQGQPAQASPSSGRQSGNSERKRKEPREKDKEKEKEKNSCVIL
570 580 590 600 610 620
>>CCDS45268.1 FAM63B gene_id:54629|Hs108|chr15 (620 aa)
initn: 1388 init1: 1253 opt: 1409 Z-score: 1227.7 bits: 236.9 E(32554): 4.6e-62
Smith-Waterman score: 1432; 54.4% identity (74.1% similar) in 432 aa overlap (58-465:185-607)
30 40 50 60 70 80
pF1KA1 LAGPDEHPQDTDARDADGEAREREPADQALLPSQCGDN----LESPLPEAS-SAPPGPTL
.::.: : :. .:: .: :
CCDS45 GGLSSSCSDPSPPGESPSLDSLESFSNLHSFPSSCEFNSEEGAENRVPEEEEGAAVLP--
160 170 180 190 200 210
90 100 110 120 130 140
pF1KA1 GTLPEVETIRACSMPQELPQSPRTRQPEPDFYCVKWIPWKGEQTPIITQSTNGPCPLLAI
:..: . .. : : : . : : . : .::: :: :.::::::. :::::::::
CCDS45 GAVPLCKEEEGEETAQVLAAS-KERFPGQSVYHIKWIQWKEENTPIITQNENGPCPLLAI
220 230 240 250 260 270
150 160 170 180 190 200
pF1KA1 MNILFLQWKVKLPPQKEVITSDELMAHLGNCLLSIKPQEKSEGLQLNFQQNVDDAMTVLP
.:.:.: :::::::. :.::...:: .::. .:. ::.: :: .::..::..:::..:
CCDS45 LNVLLLAWKVKLPPMMEIITAEQLMEYLGDYMLDAKPKEISEIQRLNYEQNMSDAMAILH
280 290 300 310 320 330
210 220 230 240 250 260
pF1KA1 KLATGLDVNVRFTGVSDFEYTPECSVFDLLGIPLYHGWLVDPQSPEAVRAVGKLSYNQLV
:: :::::::::::: ::::::: ::::: :::::::::::: . :.:::. ::::::
CCDS45 KLQTGLDVNVRFTGVRVFEYTPECIVFDLLDIPLYHGWLVDPQIDDIVKAVGNCSYNQLV
340 350 360 370 380 390
270 280 290 300 310 320
pF1KA1 ERIITCKHSSDTNLVTEGLIAEQFLETTAAQLTYHGLCELTAAAKEGELSVFFRNNHFST
:.::.::.:....::.::..:::::..::.:::::::::::....:::: ::::::::::
CCDS45 EKIISCKQSDNSELVSEGFVAEQFLNNTATQLTYHGLCELTSTVQEGELCVFFRNNHFST
400 410 420 430 440 450
330 340 350 360 370 380
pF1KA1 MTKHKSHLYLLVTDQGFLQEEQVVWESLHNVDGDSCFCDSDFHLSHSLGKGPGAEGGSGS
:::.:..::::::::::: ::.::::::::::::. ::::.::: : .. .
CCDS45 MTKYKGQLYLLVTDQGFLTEEKVVWESLHNVDGDGNFCDSEFHLR------PPSDPETVY
460 470 480 490 500
390 400 410 420
pF1KA1 PEKQLQVDQDYLIALSLQQQQPRG-------PLGLTDLELAQQLQQEE------YQQQQA
.: :.:::::.::::::.: : :..:::::..::.:: : :.:
CCDS45 KGQQDQIDQDYLMALSLQQEQQSQEINWEQIPEGISDLELAKKLQEEEDRRASQYYQEQE
510 520 530 540 550 560
430 440 450 460
pF1KA1 AQPVRMRTRVLSLQGRGA----TSGRPAG--ERRQRPKHESDCILL
. . . ::. : .::: .: ::... .:.:
CCDS45 QAAAAAAAASTQAQGQPAQASPSSGRQSGNSERKRKEPREKDKEKEKEKNSCVIL
570 580 590 600 610 620
469 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 21:08:13 2016 done: Wed Nov 2 21:08:14 2016
Total Scan time: 3.420 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]