Result of FASTA (omim) for
pF1KA1385
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1385, 736 aa
1>>>pF1KA1385 736 - 736 aa - 736 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.6092+/-0.000334; mu= 5.4496+/- 0.021
mean_var=160.4708+/-32.384, 0's: 0 Z-trim(120.2): 24 B-trim: 39 in 1/59
Lambda= 0.101246
statistics sampled from 35166 (35190) to 35166 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.73), E-opt: 0.2 (0.413), width: 16
Scan time: 10.730
The best scores are: opt bits E(85289)
NP_001019389 (OMIM: 149400,603930,615501) gephyrin ( 736) 4851 720.6 5.4e-207
XP_011534649 (OMIM: 149400,603930,615501) PREDICTE ( 749) 4208 626.7 1e-178
XP_016876412 (OMIM: 149400,603930,615501) PREDICTE ( 659) 3259 488.1 4.9e-137
XP_016876409 (OMIM: 149400,603930,615501) PREDICTE ( 722) 3259 488.1 5.3e-137
NP_065857 (OMIM: 149400,603930,615501) gephyrin is ( 769) 3259 488.1 5.6e-137
XP_011534647 (OMIM: 149400,603930,615501) PREDICTE ( 782) 3259 488.1 5.7e-137
XP_005267311 (OMIM: 149400,603930,615501) PREDICTE ( 755) 2996 449.7 2e-125
XP_016876407 (OMIM: 149400,603930,615501) PREDICTE ( 768) 2996 449.7 2.1e-125
XP_011534645 (OMIM: 149400,603930,615501) PREDICTE ( 801) 2989 448.7 4.4e-125
XP_016876415 (OMIM: 149400,603930,615501) PREDICTE ( 462) 2977 446.8 9.1e-125
XP_016876413 (OMIM: 149400,603930,615501) PREDICTE ( 486) 2970 445.8 1.9e-124
XP_016876405 (OMIM: 149400,603930,615501) PREDICTE ( 776) 2973 446.3 2.1e-124
XP_016876404 (OMIM: 149400,603930,615501) PREDICTE ( 789) 2973 446.3 2.2e-124
XP_016876402 (OMIM: 149400,603930,615501) PREDICTE ( 822) 2973 446.3 2.2e-124
XP_016876411 (OMIM: 149400,603930,615501) PREDICTE ( 702) 2970 445.9 2.7e-124
XP_016876410 (OMIM: 149400,603930,615501) PREDICTE ( 702) 2970 445.9 2.7e-124
XP_016876408 (OMIM: 149400,603930,615501) PREDICTE ( 760) 2970 445.9 2.8e-124
XP_016876406 (OMIM: 149400,603930,615501) PREDICTE ( 773) 2970 445.9 2.9e-124
XP_011534648 (OMIM: 149400,603930,615501) PREDICTE ( 779) 2970 445.9 2.9e-124
XP_011534646 (OMIM: 149400,603930,615501) PREDICTE ( 792) 2970 445.9 3e-124
XP_016876403 (OMIM: 149400,603930,615501) PREDICTE ( 806) 2970 445.9 3e-124
XP_011534644 (OMIM: 149400,603930,615501) PREDICTE ( 812) 2970 445.9 3e-124
XP_011534642 (OMIM: 149400,603930,615501) PREDICTE ( 825) 2970 445.9 3.1e-124
XP_016876414 (OMIM: 149400,603930,615501) PREDICTE ( 485) 961 152.4 4.2e-36
>>NP_001019389 (OMIM: 149400,603930,615501) gephyrin iso (736 aa)
initn: 4851 init1: 4851 opt: 4851 Z-score: 3837.2 bits: 720.6 E(85289): 5.4e-207
Smith-Waterman score: 4851; 100.0% identity (100.0% similar) in 736 aa overlap (1-736:1-736)
10 20 30 40 50 60
pF1KA1 MATEGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MATEGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 DEIEEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPEATKEVIEREAPGMALAMLMGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEIEEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPEATKEVIEREAPGMALAMLMGSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 NVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAIDLLRDAIVKVKEVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAIDLLRDAIVKVKEVH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 DELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEEKKDSGVASTEDSSSSHITAAAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEEKKDSGVASTEDSSSSHITAAAI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 AAKIPDSIISRGVQVLPRDTASLSTTPSESPRAQATSRLSTASCPTPKVQSRCSSKENIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAKIPDSIISRGVQVLPRDTASLSTTPSESPRAQATSRLSTASCPTPKVQSRCSSKENIL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 RASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 AKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 ADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 EIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 TINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 MKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKAR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 LSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYV
670 680 690 700 710 720
730
pF1KA1 ELHKGEVVDVMVIGRL
::::::::::::::::
NP_001 ELHKGEVVDVMVIGRL
730
>>XP_011534649 (OMIM: 149400,603930,615501) PREDICTED: g (749 aa)
initn: 4837 init1: 4208 opt: 4208 Z-score: 3329.5 bits: 626.7 E(85289): 1e-178
Smith-Waterman score: 4815; 98.3% identity (98.3% similar) in 749 aa overlap (1-736:1-749)
10 20 30 40 50 60
pF1KA1 MATEGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MATEGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVP
10 20 30 40 50 60
70 80 90 100
pF1KA1 DEIEEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPE-------------ATKEVIERE
:::::::::::::::::::::::::::::::::::::: :::::::::
XP_011 DEIEEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPEKFPTFPFCGLQKGATKEVIERE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA1 APGMALAMLMGSLNVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APGMALAMLMGSLNVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAID
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA1 LLRDAIVKVKEVHDELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEEKKDSGVAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLRDAIVKVKEVHDELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEEKKDSGVAST
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA1 EDSSSSHITAAAIAAKIPDSIISRGVQVLPRDTASLSTTPSESPRAQATSRLSTASCPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDSSSSHITAAAIAAKIPDSIISRGVQVLPRDTASLSTTPSESPRAQATSRLSTASCPTP
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA1 KVQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLGTEIINY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLGTEIINY
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA1 RDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQ
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA1 VMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRG
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA1 ECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNR
490 500 510 520 530 540
530 540 550 560 570 580
pF1KA1 STLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLD
550 560 570 580 590 600
590 600 610 620 630 640
pF1KA1 IDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQ
610 620 630 640 650 660
650 660 670 680 690 700
pF1KA1 GILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSAN
670 680 690 700 710 720
710 720 730
pF1KA1 GLLMLPPKTEQYVELHKGEVVDVMVIGRL
:::::::::::::::::::::::::::::
XP_011 GLLMLPPKTEQYVELHKGEVVDVMVIGRL
730 740
>>XP_016876412 (OMIM: 149400,603930,615501) PREDICTED: g (659 aa)
initn: 4209 init1: 3259 opt: 3259 Z-score: 2581.2 bits: 488.1 E(85289): 4.9e-137
Smith-Waterman score: 4058; 95.0% identity (95.0% similar) in 659 aa overlap (111-736:1-659)
90 100 110 120 130 140
pF1KA1 LILTTGGTGFAPRDVTPEATKEVIEREAPGMALAMLMGSLNVTPLGMLSRPVCGIRGKTL
::::::::::::::::::::::::::::::
XP_016 MALAMLMGSLNVTPLGMLSRPVCGIRGKTL
10 20 30
150 160 170 180 190 200
pF1KA1 IINLPGSKKGSQECFQFILPALPHAIDLLRDAIVKVKEVHDELEDLPSPPPPLSPPPTTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IINLPGSKKGSQECFQFILPALPHAIDLLRDAIVKVKEVHDELEDLPSPPPPLSPPPTTS
40 50 60 70 80 90
210 220 230 240
pF1KA1 PHKQTEDKGVQCEEEEEEKKDSGVASTEDSSSSHITAAAIAAK-----------------
:::::::::::::::::::::::::::::::::::::::::::
XP_016 PHKQTEDKGVQCEEEEEEKKDSGVASTEDSSSSHITAAAIAAKKHPFYTSPAVVMAHGEQ
100 110 120 130 140 150
250 260 270 280
pF1KA1 ----------------IPDSIISRGVQVLPRDTASLSTTPSESPRAQATSRLSTASCPTP
::::::::::::::::::::::::::::::::::::::::::::
XP_016 PIPGLINYSHHSTDERIPDSIISRGVQVLPRDTASLSTTPSESPRAQATSRLSTASCPTP
160 170 180 190 200 210
290 300 310 320 330 340
pF1KA1 KVQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLGTEIINY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLGTEIINY
220 230 240 250 260 270
350 360 370 380 390 400
pF1KA1 RDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQ
280 290 300 310 320 330
410 420 430 440 450 460
pF1KA1 VMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRG
340 350 360 370 380 390
470 480 490 500 510 520
pF1KA1 ECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNR
400 410 420 430 440 450
530 540 550 560 570 580
pF1KA1 STLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLD
460 470 480 490 500 510
590 600 610 620 630 640
pF1KA1 IDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQ
520 530 540 550 560 570
650 660 670 680 690 700
pF1KA1 GILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSAN
580 590 600 610 620 630
710 720 730
pF1KA1 GLLMLPPKTEQYVELHKGEVVDVMVIGRL
:::::::::::::::::::::::::::::
XP_016 GLLMLPPKTEQYVELHKGEVVDVMVIGRL
640 650
>>XP_016876409 (OMIM: 149400,603930,615501) PREDICTED: g (722 aa)
initn: 4616 init1: 3259 opt: 3259 Z-score: 2580.6 bits: 488.1 E(85289): 5.3e-137
Smith-Waterman score: 4465; 95.3% identity (95.4% similar) in 722 aa overlap (48-736:1-722)
20 30 40 50 60 70
pF1KA1 GVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVPDEIEEIKETLIDWCDEK
.:::::::::::::::::::::::::::::
XP_016 MLGGTISAYKIVPDEIEEIKETLIDWCDEK
10 20 30
80 90 100 110 120 130
pF1KA1 ELNLILTTGGTGFAPRDVTPEATKEVIEREAPGMALAMLMGSLNVTPLGMLSRPVCGIRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELNLILTTGGTGFAPRDVTPEATKEVIEREAPGMALAMLMGSLNVTPLGMLSRPVCGIRG
40 50 60 70 80 90
140 150 160 170 180 190
pF1KA1 KTLIINLPGSKKGSQECFQFILPALPHAIDLLRDAIVKVKEVHDELEDLPSPPPPLSPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTLIINLPGSKKGSQECFQFILPALPHAIDLLRDAIVKVKEVHDELEDLPSPPPPLSPPP
100 110 120 130 140 150
200 210 220 230 240
pF1KA1 TTSPHKQTEDKGVQCEEEEEEKKDSGVASTEDSSSSHITAAAIAAK--------------
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTSPHKQTEDKGVQCEEEEEEKKDSGVASTEDSSSSHITAAAIAAKKHPFYTSPAVVMAH
160 170 180 190 200 210
250 260 270 280
pF1KA1 -------------------IPDSIISRGVQVLPRDTASLSTTPSESPRAQATSRLSTASC
:::::::::::::::::::::::::::::::::::::::::
XP_016 GEQPIPGLINYSHHSTDERIPDSIISRGVQVLPRDTASLSTTPSESPRAQATSRLSTASC
220 230 240 250 260 270
290 300 310 320 330 340
pF1KA1 PTPKVQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLGTEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTPKVQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLGTEI
280 290 300 310 320 330
350 360 370 380 390 400
pF1KA1 INYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVM
340 350 360 370 380 390
410 420 430 440 450 460
pF1KA1 PGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDI
400 410 420 430 440 450
470 480 490 500 510 520
pF1KA1 KRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRD
460 470 480 490 500 510
530 540 550 560 570 580
pF1KA1 SNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQ
520 530 540 550 560 570
590 600 610 620 630 640
pF1KA1 VLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALR
580 590 600 610 620 630
650 660 670 680 690 700
pF1KA1 KMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMR
640 650 660 670 680 690
710 720 730
pF1KA1 SANGLLMLPPKTEQYVELHKGEVVDVMVIGRL
::::::::::::::::::::::::::::::::
XP_016 SANGLLMLPPKTEQYVELHKGEVVDVMVIGRL
700 710 720
>>NP_065857 (OMIM: 149400,603930,615501) gephyrin isofor (769 aa)
initn: 4926 init1: 3259 opt: 3259 Z-score: 2580.1 bits: 488.1 E(85289): 5.6e-137
Smith-Waterman score: 4768; 95.7% identity (95.7% similar) in 768 aa overlap (2-736:2-769)
10 20 30 40 50 60
pF1KA1 MATEGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MATEGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 DEIEEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPEATKEVIEREAPGMALAMLMGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 DEIEEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPEATKEVIEREAPGMALAMLMGSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 NVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAIDLLRDAIVKVKEVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 NVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAIDLLRDAIVKVKEVH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 DELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEEKKDSGVASTEDSSSSHITAAAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 DELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEEKKDSGVASTEDSSSSHITAAAI
190 200 210 220 230 240
250 260
pF1KA1 AAK---------------------------------IPDSIISRGVQVLPRDTASLSTTP
::: ::::::::::::::::::::::::
NP_065 AAKKHPFYTSPAVVMAHGEQPIPGLINYSHHSTDERIPDSIISRGVQVLPRDTASLSTTP
250 260 270 280 290 300
270 280 290 300 310 320
pF1KA1 SESPRAQATSRLSTASCPTPKVQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SESPRAQATSRLSTASCPTPKVQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMD
310 320 330 340 350 360
330 340 350 360 370 380
pF1KA1 KAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDR
370 380 390 400 410 420
390 400 410 420 430 440
pF1KA1 FIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 FIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRI
430 440 450 460 470 480
450 460 470 480 490 500
pF1KA1 LVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTG
490 500 510 520 530 540
510 520 530 540 550 560
pF1KA1 NELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 NELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADV
550 560 570 580 590 600
570 580 590 600 610 620
pF1KA1 IITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 IITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGN
610 620 630 640 650 660
630 640 650 660 670 680
pF1KA1 PVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLP
670 680 690 700 710 720
690 700 710 720 730
pF1KA1 WAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 WAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL
730 740 750 760
>>XP_011534647 (OMIM: 149400,603930,615501) PREDICTED: g (782 aa)
initn: 4912 init1: 3259 opt: 3259 Z-score: 2580.0 bits: 488.1 E(85289): 5.7e-137
Smith-Waterman score: 4644; 94.0% identity (94.0% similar) in 768 aa overlap (15-736:15-782)
10 20 30 40 50 60
pF1KA1 MATEGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVP
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MATEGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVP
10 20 30 40 50 60
70 80 90 100
pF1KA1 DEIEEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPE-------------ATKEVIERE
:::::::::::::::::::::::::::::::::::::: :::::::::
XP_011 DEIEEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPEKFPTFPFCGLQKGATKEVIERE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA1 APGMALAMLMGSLNVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APGMALAMLMGSLNVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAID
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA1 LLRDAIVKVKEVHDELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEEKKDSGVAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLRDAIVKVKEVHDELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEEKKDSGVAST
190 200 210 220 230 240
230 240 250
pF1KA1 EDSSSSHITAAAIAAK---------------------------------IPDSIISRGVQ
:::::::::::::::: :::::::::::
XP_011 EDSSSSHITAAAIAAKKHPFYTSPAVVMAHGEQPIPGLINYSHHSTDERIPDSIISRGVQ
250 260 270 280 290 300
260 270 280 290 300 310
pF1KA1 VLPRDTASLSTTPSESPRAQATSRLSTASCPTPKVQSRCSSKENILRASHSAVDITKVAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLPRDTASLSTTPSESPRAQATSRLSTASCPTPKVQSRCSSKENILRASHSAVDITKVAR
310 320 330 340 350 360
320 330 340 350 360 370
pF1KA1 RHRMSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RHRMSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKD
370 380 390 400 410 420
380 390 400 410 420 430
pF1KA1 GYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIR
430 440 450 460 470 480
440 450 460 470 480 490
pF1KA1 ESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVE
490 500 510 520 530 540
500 510 520 530 540 550
pF1KA1 VNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDL
550 560 570 580 590 600
560 570 580 590 600 610
pF1KA1 LNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDI
610 620 630 640 650 660
620 630 640 650 660 670
pF1KA1 DGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYH
670 680 690 700 710 720
680 690 700 710 720 730
pF1KA1 RCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIG
730 740 750 760 770 780
pF1KA1 RL
::
XP_011 RL
>>XP_005267311 (OMIM: 149400,603930,615501) PREDICTED: g (755 aa)
initn: 2976 init1: 2976 opt: 2996 Z-score: 2372.6 bits: 449.7 E(85289): 2e-125
Smith-Waterman score: 4803; 97.5% identity (97.5% similar) in 755 aa overlap (1-736:1-755)
10 20 30 40 50 60
pF1KA1 MATEGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MATEGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 DEIEEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPEATKEVIEREAPGMALAMLMGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DEIEEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPEATKEVIEREAPGMALAMLMGSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 NVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAIDLLRDAIVKVKEVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAIDLLRDAIVKVKEVH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 DELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEEKKDSGVASTEDSSSSHITAAAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEEKKDSGVASTEDSSSSHITAAAI
190 200 210 220 230 240
250 260 270 280
pF1KA1 AAKIPDSIISRGVQVLPRDTASLSTTPSESPRAQATSRLSTASCPTPK------------
::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAKIPDSIISRGVQVLPRDTASLSTTPSESPRAQATSRLSTASCPTPKQIRRPDESKGVA
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA1 -------VQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLG
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRVGSLKVQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLG
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA1 TEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQ
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA1 TVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIG
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA1 HDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGK
490 500 510 520 530 540
530 540 550 560 570 580
pF1KA1 IRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDY
550 560 570 580 590 600
590 600 610 620 630 640
pF1KA1 LKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVP
610 620 630 640 650 660
650 660 670 680 690 700
pF1KA1 ALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLM
670 680 690 700 710 720
710 720 730
pF1KA1 SMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL
:::::::::::::::::::::::::::::::::::
XP_005 SMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL
730 740 750
>>XP_016876407 (OMIM: 149400,603930,615501) PREDICTED: g (768 aa)
initn: 3715 init1: 2976 opt: 2996 Z-score: 2372.5 bits: 449.7 E(85289): 2.1e-125
Smith-Waterman score: 4767; 95.8% identity (95.8% similar) in 768 aa overlap (1-736:1-768)
10 20 30 40 50 60
pF1KA1 MATEGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MATEGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVP
10 20 30 40 50 60
70 80 90 100
pF1KA1 DEIEEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPE-------------ATKEVIERE
:::::::::::::::::::::::::::::::::::::: :::::::::
XP_016 DEIEEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPEKFPTFPFCGLQKGATKEVIERE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA1 APGMALAMLMGSLNVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APGMALAMLMGSLNVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAID
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA1 LLRDAIVKVKEVHDELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEEKKDSGVAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLRDAIVKVKEVHDELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEEKKDSGVAST
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA1 EDSSSSHITAAAIAAKIPDSIISRGVQVLPRDTASLSTTPSESPRAQATSRLSTASCPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDSSSSHITAAAIAAKIPDSIISRGVQVLPRDTASLSTTPSESPRAQATSRLSTASCPTP
250 260 270 280 290 300
290 300 310 320
pF1KA1 K-------------------VQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDK
: ::::::::::::::::::::::::::::::::::::::::
XP_016 KQIRRPDESKGVASRVGSLKVQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDK
310 320 330 340 350 360
330 340 350 360 370 380
pF1KA1 AFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRF
370 380 390 400 410 420
390 400 410 420 430 440
pF1KA1 IIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRIL
430 440 450 460 470 480
450 460 470 480 490 500
pF1KA1 VQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGN
490 500 510 520 530 540
510 520 530 540 550 560
pF1KA1 ELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVI
550 560 570 580 590 600
570 580 590 600 610 620
pF1KA1 ITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNP
610 620 630 640 650 660
630 640 650 660 670 680
pF1KA1 VSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPW
670 680 690 700 710 720
690 700 710 720 730
pF1KA1 AQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL
730 740 750 760
>>XP_011534645 (OMIM: 149400,603930,615501) PREDICTED: g (801 aa)
initn: 4629 init1: 2976 opt: 2989 Z-score: 2366.7 bits: 448.7 E(85289): 4.4e-125
Smith-Waterman score: 4474; 91.5% identity (91.5% similar) in 768 aa overlap (34-736:34-801)
10 20 30 40 50 60
pF1KA1 EGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVPDEI
::::::::::::::::::::::::::::::
XP_011 EGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVPDEI
10 20 30 40 50 60
70 80 90 100 110
pF1KA1 EEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPE-------------ATKEVIEREAPG
::::::::::::::::::::::::::::::::::: ::::::::::::
XP_011 EEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPEKFPTFPFCGLQKGATKEVIEREAPG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KA1 MALAMLMGSLNVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAIDLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MALAMLMGSLNVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAIDLLR
130 140 150 160 170 180
180 190 200 210 220 230
pF1KA1 DAIVKVKEVHDELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEEKKDSGVASTEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAIVKVKEVHDELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEEKKDSGVASTEDS
190 200 210 220 230 240
240 250
pF1KA1 SSSHITAAAIAAK---------------------------------IPDSIISRGVQVLP
::::::::::::: ::::::::::::::
XP_011 SSSHITAAAIAAKKHPFYTSPAVVMAHGEQPIPGLINYSHHSTDERIPDSIISRGVQVLP
250 260 270 280 290 300
260 270 280 290
pF1KA1 RDTASLSTTPSESPRAQATSRLSTASCPTPK-------------------VQSRCSSKEN
::::::::::::::::::::::::::::::: ::::::::::
XP_011 RDTASLSTTPSESPRAQATSRLSTASCPTPKQIRRPDESKGVASRVGSLKVQSRCSSKEN
310 320 330 340 350 360
300 310 320 330 340 350
pF1KA1 ILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQD
370 380 390 400 410 420
360 370 380 390 400 410
pF1KA1 VYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIP
430 440 450 460 470 480
420 430 440 450 460 470
pF1KA1 CGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMG
490 500 510 520 530 540
480 490 500 510 520 530
pF1KA1 PSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHG
550 560 570 580 590 600
540 550 560 570 580 590
pF1KA1 YPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGR
610 620 630 640 650 660
600 610 620 630 640 650
pF1KA1 VFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIK
670 680 690 700 710 720
660 670 680 690 700 710
pF1KA1 ARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQ
730 740 750 760 770 780
720 730
pF1KA1 YVELHKGEVVDVMVIGRL
::::::::::::::::::
XP_011 YVELHKGEVVDVMVIGRL
790 800
>>XP_016876415 (OMIM: 149400,603930,615501) PREDICTED: g (462 aa)
initn: 2972 init1: 2972 opt: 2977 Z-score: 2361.0 bits: 446.8 E(85289): 9.1e-125
Smith-Waterman score: 2977; 97.6% identity (98.5% similar) in 464 aa overlap (273-736:2-462)
250 260 270 280 290 300
pF1KA1 KIPDSIISRGVQVLPRDTASLSTTPSESPRAQATSRLSTASCPTPKVQSRCSSKENILRA
: :.. .::: .::::::::::::::
XP_016 MAPQTTERATASL---QVQSRCSSKENILRA
10 20
310 320 330 340 350 360
pF1KA1 SHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAK
30 40 50 60 70 80
370 380 390 400 410 420
pF1KA1 DNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGAD
90 100 110 120 130 140
430 440 450 460 470 480
pF1KA1 AVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEI
150 160 170 180 190 200
490 500 510 520 530 540
pF1KA1 GLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTI
210 220 230 240 250 260
550 560 570 580 590 600
pF1KA1 NLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMK
270 280 290 300 310 320
610 620 630 640 650 660
pF1KA1 PGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLS
330 340 350 360 370 380
670 680 690 700 710 720
pF1KA1 CDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVEL
390 400 410 420 430 440
730
pF1KA1 HKGEVVDVMVIGRL
::::::::::::::
XP_016 HKGEVVDVMVIGRL
450 460
736 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 21:07:29 2016 done: Wed Nov 2 21:07:31 2016
Total Scan time: 10.730 Total Display time: 0.180
Function used was FASTA [36.3.4 Apr, 2011]