FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1375, 868 aa
1>>>pF1KA1375 868 - 868 aa - 868 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 15.1491+/-0.00139; mu= -19.7293+/- 0.085
mean_var=730.5414+/-150.103, 0's: 0 Z-trim(114.5): 28 B-trim: 0 in 0/53
Lambda= 0.047452
statistics sampled from 15079 (15097) to 15079 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.748), E-opt: 0.2 (0.464), width: 16
Scan time: 4.280
The best scores are: opt bits E(32554)
CCDS2660.1 PDCD6IP gene_id:10015|Hs108|chr3 ( 868) 5718 407.2 6.3e-113
CCDS54561.1 PDCD6IP gene_id:10015|Hs108|chr3 ( 873) 5698 405.9 1.6e-112
CCDS2754.1 PTPN23 gene_id:25930|Hs108|chr3 (1636) 866 75.3 9.7e-13
>>CCDS2660.1 PDCD6IP gene_id:10015|Hs108|chr3 (868 aa)
initn: 5718 init1: 5718 opt: 5718 Z-score: 2140.9 bits: 407.2 E(32554): 6.3e-113
Smith-Waterman score: 5718; 100.0% identity (100.0% similar) in 868 aa overlap (1-868:1-868)
10 20 30 40 50 60
pF1KA1 MATFISVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRRAAVGRPLDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 MATFISVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRRAAVGRPLDK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 HEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 HEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYEK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 SCVLFNCAALASQIAAEQNLDNDEGLKIAAKHYQFASGAFLHIKETVLSALSREPTVDIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 SCVLFNCAALASQIAAEQNLDNDEGLKIAAKHYQFASGAFLHIKETVLSALSREPTVDIS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 PDTVGTLSLIMLAQAQEVFFLKATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDTLPKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 PDTVGTLSLIMLAQAQEVFFLKATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDTLPKE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 VFPVLAAKHCIMQANAEYHQSILAKQQKKFGEEIARLQHAAELIKTVASRYDEYVNVKDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 VFPVLAAKHCIMQANAEYHQSILAKQQKKFGEEIARLQHAAELIKTVASRYDEYVNVKDF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 SDKINRALAAAKKDNDFIYHDRVPDLKDLDPIGKATLVKSTPVNVPISQKFTDLFEKMVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 SDKINRALAAAKKDNDFIYHDRVPDLKDLDPIGKATLVKSTPVNVPISQKFTDLFEKMVP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 VSVQQSLAAYNQRKADLVNRSIAQMREATTLANGVLASLNLPAAIEDVSGDTVPQSILTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 VSVQQSLAAYNQRKADLVNRSIAQMREATTLANGVLASLNLPAAIEDVSGDTVPQSILTK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 SRSVIEQGGIQTVDQLIKELPELLQRNREILDESLRLLDEEEATDNDLRAKFKERWQRTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 SRSVIEQGGIQTVDQLIKELPELLQRNREILDESLRLLDEEEATDNDLRAKFKERWQRTP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 SNELYKPLRAEGTNFRTVLDKAVQADGQVKECYQSHRDTIVLLCKPEPELNAAIPSANPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 SNELYKPLRAEGTNFRTVLDKAVQADGQVKECYQSHRDTIVLLCKPEPELNAAIPSANPA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 KTMQGSEVVNVLKSLLSNLDEVKKEREGLENDLKSVNFDMTSKFLTALAQDGVINEEALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 KTMQGSEVVNVLKSLLSNLDEVKKEREGLENDLKSVNFDMTSKFLTALAQDGVINEEALS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 VTELDRVYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREEVLKNLATAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 VTELDRVYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREEVLKNLATAY
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 DNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAREPSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 DNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAREPSAP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 SIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSPVGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 SIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSPVGAG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 TAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPPVYHQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 TAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPPVYHQS
790 800 810 820 830 840
850 860
pF1KA1 PGQAPYPGPQQPSYPFPQPPQQSYYPQQ
::::::::::::::::::::::::::::
CCDS26 PGQAPYPGPQQPSYPFPQPPQQSYYPQQ
850 860
>>CCDS54561.1 PDCD6IP gene_id:10015|Hs108|chr3 (873 aa)
initn: 4172 init1: 4172 opt: 5698 Z-score: 2133.5 bits: 405.9 E(32554): 1.6e-112
Smith-Waterman score: 5698; 99.4% identity (99.4% similar) in 873 aa overlap (1-868:1-873)
10 20 30 40 50 60
pF1KA1 MATFISVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRRAAVGRPLDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MATFISVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRRAAVGRPLDK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 HEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 HEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYEK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 SCVLFNCAALASQIAAEQNLDNDEGLKIAAKHYQFASGAFLHIKETVLSALSREPTVDIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SCVLFNCAALASQIAAEQNLDNDEGLKIAAKHYQFASGAFLHIKETVLSALSREPTVDIS
130 140 150 160 170 180
190 200 210 220 230
pF1KA1 PDTVGTLSLIMLAQAQEVFFLKATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDTLPK-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PDTVGTLSLIMLAQAQEVFFLKATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDTLPKY
190 200 210 220 230 240
240 250 260 270 280 290
pF1KA1 ----EVFPVLAAKHCIMQANAEYHQSILAKQQKKFGEEIARLQHAAELIKTVASRYDEYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 FYFQEVFPVLAAKHCIMQANAEYHQSILAKQQKKFGEEIARLQHAAELIKTVASRYDEYV
250 260 270 280 290 300
300 310 320 330 340 350
pF1KA1 NVKDFSDKINRALAAAKKDNDFIYHDRVPDLKDLDPIGKATLVKSTPVNVPISQKFTDLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NVKDFSDKINRALAAAKKDNDFIYHDRVPDLKDLDPIGKATLVKSTPVNVPISQKFTDLF
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA1 EKMVPVSVQQSLAAYNQRKADLVNRSIAQMREATTLANGVLASLNLPAAIEDVSGDTVPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EKMVPVSVQQSLAAYNQRKADLVNRSIAQMREATTLANGVLASLNLPAAIEDVSGDTVPQ
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA1 SILTKSRSVIEQGGIQTVDQLIKELPELLQRNREILDESLRLLDEEEATDNDLRAKFKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SILTKSRSVIEQGGIQTVDQLIKELPELLQRNREILDESLRLLDEEEATDNDLRAKFKER
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA1 WQRTPSNELYKPLRAEGTNFRTVLDKAVQADGQVKECYQSHRDTIVLLCKPEPELNAAIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 WQRTPSNELYKPLRAEGTNFRTVLDKAVQADGQVKECYQSHRDTIVLLCKPEPELNAAIP
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA1 SANPAKTMQGSEVVNVLKSLLSNLDEVKKEREGLENDLKSVNFDMTSKFLTALAQDGVIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SANPAKTMQGSEVVNVLKSLLSNLDEVKKEREGLENDLKSVNFDMTSKFLTALAQDGVIN
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA1 EEALSVTELDRVYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREEVLKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EEALSVTELDRVYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREEVLKN
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA1 LATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAR
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA1 EPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPS
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA1 PVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPP
790 800 810 820 830 840
840 850 860
pF1KA1 VYHQSPGQAPYPGPQQPSYPFPQPPQQSYYPQQ
:::::::::::::::::::::::::::::::::
CCDS54 VYHQSPGQAPYPGPQQPSYPFPQPPQQSYYPQQ
850 860 870
>>CCDS2754.1 PTPN23 gene_id:25930|Hs108|chr3 (1636 aa)
initn: 330 init1: 143 opt: 866 Z-score: 342.2 bits: 75.3 E(32554): 9.7e-13
Smith-Waterman score: 980; 27.5% identity (58.0% similar) in 902 aa overlap (5-867:10-872)
10 20 30 40 50
pF1KA1 MATFISVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRRAAVG
: ..::.... . . ::. ..: ::. : . ..: ::. ::
CCDS27 MEAVPRMPMIWLDLKEAGDFHFQPAVKKFVLKNY---GENPEAYNEELKKLELLRQNAVR
10 20 30 40 50
60 70 80 90 100 110
pF1KA1 RPLDKHEGALETLLRYYDQICSIEPKFPFSENQ-ICLTFTWKDAFDKGSLFGGSVKLALA
: : :: .: .: :. .. . :.. .: . :: . :. : :: :
CCDS27 VPRD-FEGC-SVLRKYLGQLHYLQSRVPMGSGQEAAVPVTWTEIFS-----GKSV--AHE
60 70 80 90 100
120 130 140 150 160 170
pF1KA1 SLGYEKSCVLFNCAALASQIAAEQNLDNDEGLKIAAKHYQFASGAFLHIKETVLSALSRE
.. ::..:.:.: .:: :...: .. ..::.:.. :.: :.::: ...: .: :
CCDS27 DIKYEQACILYNLGALHSMLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYS--
110 120 130 140 150 160
180 190 200 210 220 230
pF1KA1 PTVDISPDTVGTLSL-IMLAQAQEVFFLKATRDKMKDAIIAKLANQAADYFGDAFKQCQY
::.: . ::.. .::.:::: .. :. :. :. ..:... :..::. .: . .
CCDS27 --VDMS-RQILTLNVNLMLGQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEACRALEN
170 180 190 200 210 220
240 250 260 270 280
pF1KA1 KDT------LPKEVFPVLAAKHCIMQANAEYHQSILAKQQKKFGEEIARLQHA----AEL
:: . :. .. : . : :. :.. :..:.::::..: .: : :
CCDS27 PDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVAYFQSALDKLNEA
230 240 250 260 270 280
290 300 310 320 330 340
pF1KA1 IKTVASRYDEYVNVKDFS-DKINRALAAAKKDNDFIYHDRVPDLKDLDPIGKATLVKSTP
:: . .. : .. :. : :. .::::::::::. :: : :.:. : ::: :
CCDS27 IKLAKGQPDTVQDALRFTMDVIGGKYNSAKKDNDFIYHEAVPALDTLQPVKGAPLVKPLP
290 300 310 320 330 340
350 360 370 380 390 400
pF1KA1 VNVPISQKFT--DLFEKMVPVSVQQSLAAYNQRKADLVNRSIAQMREATTLANGVLASLN
:: : . : :.: :.::...... . :...:: :. . .:.... . . . . :..
CCDS27 VN-PTDPAVTGPDIFAKLVPMAAHEASSLYSEEKAKLLREMMAKIEDKNEVLDQFMDSMQ
350 360 370 380 390 400
410 420 430 440 450
pF1KA1 L-PAAIEDVSGDT-VPQSILTKSRSV-IEQGGIQTVDQLIKELPELLQRNREILDESLRL
: : ....... . .: ... : .. .. .... : .. : .. . : . :
CCDS27 LDPETVDNLDAYSHIPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDL
410 420 430 440 450 460
460 470 480 490 500 510
pF1KA1 LDEEEATDNDLRAKFKERWQR------TPSNELYKPLRAEGTNFRTVLDKAVQADGQVKE
:.:.: :. ::.: . : . :: . .: : ... : .:: .......
CCDS27 LEEDEL----LEQKFQEAVGQAGAISITSKAELAE-VRREWAKYMEVHEKASFTNSELHR
470 480 490 500 510
520 530 540 550 560 570
pF1KA1 CYQSHRDTIVLLCKPEPELNAAIPSANPAKTMQGSEVVNVLKSLLSNLDEVKKEREGLEN
.. : .. :: : .. ::.:. :: . . . :.. :: .:....:.. .: .::.
CCDS27 AMNLHVGNLRLLSGPLDQVRAALPT--PALSPEDKAVLQNLKRILAKVQEMRDQRVSLEQ
520 530 540 550 560 570
580 590 600 610 620
pF1KA1 DLKSV--NFDMTSKFLTALAQDGVINEEALSVTELDRVYGGLTTKVQESLKKQEGLLKNI
.:. . . :.:....:. : .: : . : : . ....: :. .: .
CCDS27 QLRELIQKDDITASLVTT---DH--SEMKKLFEEQLKKYDQLKVYLEQNLAAQDRVLCAL
580 590 600 610 620 630
630 640 650 660 670 680
pF1KA1 QVSHQEFSKMKQSNNEANLR-EEVLKNLATAYDNFVELVANLKEGTKFYNEL----TEIL
.. ... ... .. . . . .:..:...:. . .:. . .:: :: .: . .:
CCDS27 TEANVQYAAVRRVLSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGRDFYADLESKVAALL
640 650 660 670 680 690
690 700 710 720 730 740
pF1KA1 VRFQNKCSDIVFARKTERDELL-KDLQQSIAREPSAPSIPTPAYQSSPAGGHAPTPPTPA
: :. :. ::.. :..:: ..:... .:.::. : . : : .: ::
CCDS27 ERTQSTCQ----AREAARQQLLDRELKKKPPPRPTAPKPLLPRREESEAV-EAGDPPEEL
700 710 720 730 740
750 760 770 780 790 800
pF1KA1 PRTMPPTKPQPPARPPPPVLPANRAPSATAPSPVGAGTAAPAPSQTPGSAPPPQAQGPPY
:..:: : : : : .. .: ::: ..:. :.: : :: .::
CCDS27 -RSLPPDMVAGP-RLPDTFL-GSATPLHFPPSPFPSSTG-PGPHYLSGPLPPGTYSGPTQ
750 760 770 780 790 800
810 820 830 840 850
pF1KA1 PTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPPVYHQSPGQ----APYPG--PQQPSYPFP
: :: ::. : : :. : ..:: . .:: : : : .:
CCDS27 LIQPRAPGPHAMPVAPGPALYPAPAYTPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLP
810 820 830 840 850 860
860
pF1KA1 Q-PPQQSYYPQQ
. :: : :.
CCDS27 SAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTP
870 880 890 900 910 920
868 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 20:00:02 2016 done: Thu Nov 3 20:00:02 2016
Total Scan time: 4.280 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]