FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA1321, 695 aa
  1>>>pF1KA1321 695 - 695 aa - 695 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.0923+/-0.000438; mu= -3.4881+/- 0.027
 mean_var=217.0840+/-45.657, 0's: 0 Z-trim(118.3): 46  B-trim: 1139 in 2/51
 Lambda= 0.087048
 statistics sampled from 30990 (31041) to 30990 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.69), E-opt: 0.2 (0.364), width:  16
 Scan time:  9.310

The best scores are:                                      opt bits E(85289)
NP_065823 (OMIM: 609356) nuclear fragile X mental  ( 695) 4631 594.9 3.4e-169
XP_016880385 (OMIM: 609356) PREDICTED: nuclear fra ( 536) 3480 450.3 8.9e-126


>>NP_065823 (OMIM: 609356) nuclear fragile X mental reta  (695 aa)
 initn: 4631 init1: 4631 opt: 4631  Z-score: 3158.5  bits: 594.9 E(85289): 3.4e-169
Smith-Waterman score: 4631; 100.0% identity (100.0% similar) in 695 aa overlap (1-695:1-695)

               10        20        30        40        50        60
pF1KA1 MEEKPGQPQPQHHHSHHHPHHHPQQQQQQPHHHHHYYFYNHSHNHHHHHHHQQPHQYLQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MEEKPGQPQPQHHHSHHHPHHHPQQQQQQPHHHHHYYFYNHSHNHHHHHHHQQPHQYLQH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 GAEGSPKAQPKPLKHEQKHTLQQHQETPKKKTGYGELNGNAGEREISLKNLSSDEATNPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GAEGSPKAQPKPLKHEQKHTLQQHQETPKKKTGYGELNGNAGEREISLKNLSSDEATNPI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 SRVLNGNQQVVDTSLKQTVKANTFGKAGIKTKNFIQKNSMDKKNGKSYENKSGENQSVDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SRVLNGNQQVVDTSLKQTVKANTFGKAGIKTKNFIQKNSMDKKNGKSYENKSGENQSVDK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 SDTIPIPNGVVTNNSGYITNGYMGKGADNDGSGSESGYTTPKKRKARRNSAKGCENLNIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SDTIPIPNGVVTNNSGYITNGYMGKGADNDGSGSESGYTTPKKRKARRNSAKGCENLNIV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 QDKIMQQETSVPTLKQGLETFKPDYSEQKGNRVDGSKPIWKYETGPGGTSRGKPAVGDML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 QDKIMQQETSVPTLKQGLETFKPDYSEQKGNRVDGSKPIWKYETGPGGTSRGKPAVGDML
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 RKSSDSKPGVSSKKFDDRPKGKHASAVASKEDSWTLFKPPPVFPVDNSSAKIVPKISYAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 RKSSDSKPGVSSKKFDDRPKGKHASAVASKEDSWTLFKPPPVFPVDNSSAKIVPKISYAS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 KVKENLNKTIQNSSVSPTSSSSSSSSTGETQTQSSSRLSQVPMSALKSVTSANFSNGPVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KVKENLNKTIQNSSVSPTSSSSSSSSTGETQTQSSSRLSQVPMSALKSVTSANFSNGPVL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 AGTDGNVYPPGGQPLLTTAANTLTPISSGTDSVLQDMSLTSAAVEQIKTSLFIYPSNMQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 AGTDGNVYPPGGQPLLTTAANTLTPISSGTDSVLQDMSLTSAAVEQIKTSLFIYPSNMQT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 MLLSTAQVDLPSQTDQQNLGDIFQNQWGLSFINEPSAGPETVTGKSSEHKVMEVTFQGEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MLLSTAQVDLPSQTDQQNLGDIFQNQWGLSFINEPSAGPETVTGKSSEHKVMEVTFQGEY
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA1 PATLVSQGAEIIPSGTEHPVFPKAYELEKRTSPQVLGSILKSGTTSESGALSLEPSHIGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PATLVSQGAEIIPSGTEHPVFPKAYELEKRTSPQVLGSILKSGTTSESGALSLEPSHIGD
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA1 LQKADTSSQGALVFLSKDYEIESQNPLASPTNTLLGSAKEQRYQRGLERNDSWGSFDLRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LQKADTSSQGALVFLSKDYEIESQNPLASPTNTLLGSAKEQRYQRGLERNDSWGSFDLRA
              610       620       630       640       650       660

              670       680       690     
pF1KA1 AIVYHTKEMESIWNLQKQDPKRIITYNEAMDSPDQ
       :::::::::::::::::::::::::::::::::::
NP_065 AIVYHTKEMESIWNLQKQDPKRIITYNEAMDSPDQ
              670       680       690     

>>XP_016880385 (OMIM: 609356) PREDICTED: nuclear fragile  (536 aa)
 initn: 3480 init1: 3480 opt: 3480  Z-score: 2379.1  bits: 450.3 E(85289): 8.9e-126
Smith-Waterman score: 3480; 100.0% identity (100.0% similar) in 536 aa overlap (160-695:1-536)

     130       140       150       160       170       180         
pF1KA1 VVDTSLKQTVKANTFGKAGIKTKNFIQKNSMDKKNGKSYENKSGENQSVDKSDTIPIPNG
                                     ::::::::::::::::::::::::::::::
XP_016                               MDKKNGKSYENKSGENQSVDKSDTIPIPNG
                                             10        20        30

     190       200       210       220       230       240         
pF1KA1 VVTNNSGYITNGYMGKGADNDGSGSESGYTTPKKRKARRNSAKGCENLNIVQDKIMQQET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVTNNSGYITNGYMGKGADNDGSGSESGYTTPKKRKARRNSAKGCENLNIVQDKIMQQET
               40        50        60        70        80        90

     250       260       270       280       290       300         
pF1KA1 SVPTLKQGLETFKPDYSEQKGNRVDGSKPIWKYETGPGGTSRGKPAVGDMLRKSSDSKPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVPTLKQGLETFKPDYSEQKGNRVDGSKPIWKYETGPGGTSRGKPAVGDMLRKSSDSKPG
              100       110       120       130       140       150

     310       320       330       340       350       360         
pF1KA1 VSSKKFDDRPKGKHASAVASKEDSWTLFKPPPVFPVDNSSAKIVPKISYASKVKENLNKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSSKKFDDRPKGKHASAVASKEDSWTLFKPPPVFPVDNSSAKIVPKISYASKVKENLNKT
              160       170       180       190       200       210

     370       380       390       400       410       420         
pF1KA1 IQNSSVSPTSSSSSSSSTGETQTQSSSRLSQVPMSALKSVTSANFSNGPVLAGTDGNVYP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQNSSVSPTSSSSSSSSTGETQTQSSSRLSQVPMSALKSVTSANFSNGPVLAGTDGNVYP
              220       230       240       250       260       270

     430       440       450       460       470       480         
pF1KA1 PGGQPLLTTAANTLTPISSGTDSVLQDMSLTSAAVEQIKTSLFIYPSNMQTMLLSTAQVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGGQPLLTTAANTLTPISSGTDSVLQDMSLTSAAVEQIKTSLFIYPSNMQTMLLSTAQVD
              280       290       300       310       320       330

     490       500       510       520       530       540         
pF1KA1 LPSQTDQQNLGDIFQNQWGLSFINEPSAGPETVTGKSSEHKVMEVTFQGEYPATLVSQGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPSQTDQQNLGDIFQNQWGLSFINEPSAGPETVTGKSSEHKVMEVTFQGEYPATLVSQGA
              340       350       360       370       380       390

     550       560       570       580       590       600         
pF1KA1 EIIPSGTEHPVFPKAYELEKRTSPQVLGSILKSGTTSESGALSLEPSHIGDLQKADTSSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIIPSGTEHPVFPKAYELEKRTSPQVLGSILKSGTTSESGALSLEPSHIGDLQKADTSSQ
              400       410       420       430       440       450

     610       620       630       640       650       660         
pF1KA1 GALVFLSKDYEIESQNPLASPTNTLLGSAKEQRYQRGLERNDSWGSFDLRAAIVYHTKEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GALVFLSKDYEIESQNPLASPTNTLLGSAKEQRYQRGLERNDSWGSFDLRAAIVYHTKEM
              460       470       480       490       500       510

     670       680       690     
pF1KA1 ESIWNLQKQDPKRIITYNEAMDSPDQ
       ::::::::::::::::::::::::::
XP_016 ESIWNLQKQDPKRIITYNEAMDSPDQ
              520       530      




695 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 20:57:46 2016 done: Wed Nov  2 20:57:47 2016
 Total Scan time:  9.310 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]