FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1315, 1981 aa
1>>>pF1KA1315 1981 - 1981 aa - 1981 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.9853+/-0.00056; mu= 13.8640+/- 0.035
mean_var=221.7616+/-44.015, 0's: 0 Z-trim(112.8): 163 B-trim: 119 in 1/52
Lambda= 0.086125
statistics sampled from 21765 (21924) to 21765 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.591), E-opt: 0.2 (0.257), width: 16
Scan time: 19.190
The best scores are: opt bits E(85289)
NP_036247 (OMIM: 606880) CASP8-associated protein (1982) 12958 1625.5 0
NP_001131139 (OMIM: 606880) CASP8-associated prote (1982) 12958 1625.5 0
NP_001131140 (OMIM: 606880) CASP8-associated prote (1982) 12958 1625.5 0
XP_016864545 (OMIM: 609268) PREDICTED: splicing re ( 359) 226 42.8 0.0082
NP_001310463 (OMIM: 609268) splicing regulatory gl ( 359) 226 42.8 0.0082
>>NP_036247 (OMIM: 606880) CASP8-associated protein 2 [H (1982 aa)
initn: 11467 init1: 11467 opt: 12958 Z-score: 8712.1 bits: 1625.5 E(85289): 0
Smith-Waterman score: 12958; 99.9% identity (99.9% similar) in 1982 aa overlap (1-1981:1-1982)
10 20 30 40 50 60
pF1KA1 MAADDDNGDGTSLFDVFSASPLKNNDEGSLDIYAGLDSAVSDSASKSCVPSRNCLDLYEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MAADDDNGDGTSLFDVFSASPLKNNDEGSLDIYAGLDSAVSDSASKSCVPSRNCLDLYEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 ILTEEGTAKEATYNDLQVEYGKCQLQMKELMKKFKEIQTQNFSLINENQSLKKNISALIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ILTEEGTAKEATYNDLQVEYGKCQLQMKELMKKFKEIQTQNFSLINENQSLKKNISALIK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 TARVEINRKDEEISNLHQRLSEFPHFRNNHKTARTFDTVKTKDLKSRSPHLDDCSKTDHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 TARVEINRKDEEISNLHQRLSEFPHFRNNHKTARTFDTVKTKDLKSRSPHLDDCSKTDHR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 AKSDVSKDVHHSTSLPNLEKEGKPHSDKRSTSHLPTSVEKHCTNGVWSRSHYQVGEGSSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 AKSDVSKDVHHSTSLPNLEKEGKPHSDKRSTSHLPTSVEKHCTNGVWSRSHYQVGEGSSN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 EDSRRGRKDIRHSQFNRGTERVRKDLSTGCGDGEPRILEASQRLQGHPEKYGKGEPKTES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EDSRRGRKDIRHSQFNRGTERVRKDLSTGCGDGEPRILEASQRLQGHPEKYGKGEPKTES
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 KSSKFKSNSDSDYKGERINSSWEKETPGERSHSRVDSQSDKKLERQSERSQNINRKEVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KSSKFKSNSDSDYKGERINSSWEKETPGERSHSRVDSQSDKKLERQSERSQNINRKEVKS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 QDKEERKVDQKPKSVVKDQDHWRRSERASLPHSKNEITFSHNSSKYHLEERRGWEDCKRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 QDKEERKVDQKPKSVVKDQDHWRRSERASLPHSKNEITFSHNSSKYHLEERRGWEDCKRD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 KSVNSHSFQDGRCPSSLSNSRTHKNIDSKEVDAMHQWENTPLKAERHRTEDKRKREQESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KSVNSHSFQDGRCPSSLSNSRTHKNIDSKEVDAMHQWENTPLKAERHRTEDKRKREQESK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 EENRHIRNEKRVPTEHLQKTNKETKKTTTDLKKQNEPKTDKGEVLDNGVSEGADNKELAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EENRHIRNEKRVPTEHLQKTNKETKKTTTDLKKQNEPKTDKGEVLDNGVSEGADNKELAM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 KAESGPNETKNKDLKLSFMKKLNLTLSPAKKQPVSQDNQHKITDIPKSSGVCDSESSMQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KAESGPNETKNKDLKLSFMKKLNLTLSPAKKQPVSQDNQHKITDIPKSSGVCDSESSMQV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 KTVAYVPSISEHILGEAAVSEHTMGETKSTLLEPKVALLAVTEPRIGISETNKEDENSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KTVAYVPSISEHILGEAAVSEHTMGETKSTLLEPKVALLAVTEPRIGISETNKEDENSLL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 VRSVDNTMHCEEPICGTETSFPSPMEIQQTESLFPSTGMKQTINNGRAAAPVVMDVLQTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VRSVDNTMHCEEPICGTETSFPSPMEIQQTESLFPSTGMKQTINNGRAAAPVVMDVLQTD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 VSQNFGLELDTKRNDNSDYCGISEGMEMKVALSTTVSETTESILQPSIEEADILPIMLSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VSQNFGLELDTKRNDNSDYCGISEGMEMKVALSTTVSETTESILQPSIEEADILPIMLSE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 DNNPKFEPSVIVTPLVESKSCHLEPCLPKETLDSSLQQTELMDHRMATGETNSVYHDDDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DNNPKFEPSVIVTPLVESKSCHLEPCLPKETLDSSLQQTELMDHRMATGETNSVYHDDDN
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA1 SVLSIDLNHLRPIPEAISPLNSPVRPVAKVLRNESPPQVPVYNNSHKDVFLPNSAHSTSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SVLSIDLNHLRPIPEAISPLNSPVRPVAKVLRNESPPQVPVYNNSHKDVFLPNSAHSTSK
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA1 SQSDLNKENQKPIYKSDKCTEADTCKNSPLDELEEGEIRSDSETSKPQESFEKNSKRRVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SQSDLNKENQKPIYKSDKCTEADTCKNSPLDELEEGEIRSDSETSKPQESFEKNSKRRVS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA1 ADVRKSKTIPRRGKSTVCLDKDSRKTHVRIHQTNNKWNKRPDKSSRSSKTEKKDKVMSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ADVRKSKTIPRRGKSTVCLDKDSRKTHVRIHQTNNKWNKRPDKSSRSSKTEKKDKVMSTS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA1 SLEKIVPIIAVPSSEQEIMHMLRMIRKHVRKNYMKFKAKFSLIQFHRIIESAILSFTSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SLEKIVPIIAVPSSEQEIMHMLRMIRKHVRKNYMKFKAKFSLIQFHRIIESAILSFTSLI
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA1 KHLNLHKISKSVTTLQKNLCDIIESKLKQVKKNGIVDRLFEQQLPDMKKKLWKFVDDQLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KHLNLHKISKSVTTLQKNLCDIIESKLKQVKKNGIVDRLFEQQLPDMKKKLWKFVDDQLD
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA1 YLFAKLKKILVCDSKSFGRDSDEGKLEKTSKQNAQYSNSQKRSVDNSNRELLKEKLSKSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 YLFAKLKKILVCDSKSFGRDSDEGKLEKTSKQNAQYSNSQKRSVDNSNRELLKEKLSKSE
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA1 DPVHYKSLVGCKKSEENYQDQNNSSINTVKHDIKKNFNICFDNIKNSQSEERSLEVHCPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DPVHYKSLVGCKKSEENYQDQNNSSINTVKHDIKKNFNICFDNIKNSQSEERSLEVHCPS
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA1 TPKSEKNEGSSIEDAQTSQHATLKPERSFEILTEQQASSLTFNLVSDAQMGEIFKSLLQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 TPKSEKNEGSSIEDAQTSQHATLKPERSFEILTEQQASSLTFNLVSDAQMGEIFKSLLQG
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA1 SDLLDSSVNCTEKSEWELKTPEKQLLETLKCESIPACTTEELVSGVASPCPKMISDDNWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SDLLDSSVNCTEKSEWELKTPEKQLLETLKCESIPACTTEELVSGVASPCPKMISDDNWS
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA1 LLSSEKGPSLSSGLSLPVHPDVLDESCMFEVSTNLPLSKDNVCSVEKSKPCVSSILLEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LLSSEKGPSLSSGLSLPVHPDVLDESCMFEVSTNLPLSKDNVCSVEKSKPCVSSILLEDL
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA1 AVSLTVPSPLKSDGHLSFLKPDMSSSSTPEEVISAHFSEDALLEEEDASEQDIHLALESD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 AVSLTVPSPLKSDGHLSFLKPDMSSSSTPEEVISAHFSEDALLEEEDASEQDIHLALESD
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA1 NSSSKSSCSSSWTSRSVAPGFQYHPNLPMHAVIMEKSNDHFIVKIRRATPSTSSGLKQSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 NSSSKSSCSSSWTSRSVAPGFQYHPNLPMHAVIMEKSNDHFIVKIRRATPSTSSGLKQSM
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KA1 MPDELLTSLPRHGKEADEGPEKEYISCQNTVFKSVEELENSNKNVDGSKSTHEEQSSMIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MPDELLTSLPRHGKEADEGPEKEYISCQNTVFKSVEELENSNKNVDGSKSTHEEQSSMIQ
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KA1 TQVPDIYEFLKDASDKMGHSDEVADECFKLHQVWETKVPESIEELPSMEEISHSVGEHLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 TQVPDIYEFLKDASDKMGHSDEVADECFKLHQVWETKVPESIEELPSMEEISHSVGEHLP
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KA1 NTYVDLTKDPVTETKNLGEFIEVTVLHIDQLGCSGGNLNQSAQILDNSLQADTVGAFIDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 NTYVDLTKDPVTETKNLGEFIEVTVLHIDQLGCSGGNLNQSAQILDNSLQADTVGAFIDL
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790
pF1KA1 TQDASSEAKSEGN-PALAVEDLGCGVIQVDEDNCKEEKAQVANRPLKCIVEETYIDLTTE
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
NP_036 TQDASSEAKSEGNHPALAVEDLGCGVIQVDEDNCKEEKAQVANRPLKCIVEETYIDLTTE
1750 1760 1770 1780 1790 1800
1800 1810 1820 1830 1840 1850
pF1KA1 SPSSCEVKKDELKSEPGSNCDNSELPGTLHNSHKKRRNISDLNHPHKKQRKETDLTNKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SPSSCEVKKDELKSEPGSNCDNSELPGTLHNSHKKRRNISDLNHPHKKQRKETDLTNKEK
1810 1820 1830 1840 1850 1860
1860 1870 1880 1890 1900 1910
pF1KA1 TKKPTQDSCENTEAHQKKASKKKAPPVTKDPSSLKATPGIKDSSAALATSTSLSAKNVIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 TKKPTQDSCENTEAHQKKASKKKAPPVTKDPSSLKATPGIKDSSAALATSTSLSAKNVIK
1870 1880 1890 1900 1910 1920
1920 1930 1940 1950 1960 1970
pF1KA1 KKGEIIILWTRNDDREILLECQKRGPSFKTFAYLAAKLDKNPNQVSERFQQLMKLFEKSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KKGEIIILWTRNDDREILLECQKRGPSFKTFAYLAAKLDKNPNQVSERFQQLMKLFEKSK
1930 1940 1950 1960 1970 1980
1980
pF1KA1 CR
::
NP_036 CR
>>NP_001131139 (OMIM: 606880) CASP8-associated protein 2 (1982 aa)
initn: 11467 init1: 11467 opt: 12958 Z-score: 8712.1 bits: 1625.5 E(85289): 0
Smith-Waterman score: 12958; 99.9% identity (99.9% similar) in 1982 aa overlap (1-1981:1-1982)
10 20 30 40 50 60
pF1KA1 MAADDDNGDGTSLFDVFSASPLKNNDEGSLDIYAGLDSAVSDSASKSCVPSRNCLDLYEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAADDDNGDGTSLFDVFSASPLKNNDEGSLDIYAGLDSAVSDSASKSCVPSRNCLDLYEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 ILTEEGTAKEATYNDLQVEYGKCQLQMKELMKKFKEIQTQNFSLINENQSLKKNISALIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILTEEGTAKEATYNDLQVEYGKCQLQMKELMKKFKEIQTQNFSLINENQSLKKNISALIK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 TARVEINRKDEEISNLHQRLSEFPHFRNNHKTARTFDTVKTKDLKSRSPHLDDCSKTDHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TARVEINRKDEEISNLHQRLSEFPHFRNNHKTARTFDTVKTKDLKSRSPHLDDCSKTDHR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 AKSDVSKDVHHSTSLPNLEKEGKPHSDKRSTSHLPTSVEKHCTNGVWSRSHYQVGEGSSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKSDVSKDVHHSTSLPNLEKEGKPHSDKRSTSHLPTSVEKHCTNGVWSRSHYQVGEGSSN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 EDSRRGRKDIRHSQFNRGTERVRKDLSTGCGDGEPRILEASQRLQGHPEKYGKGEPKTES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDSRRGRKDIRHSQFNRGTERVRKDLSTGCGDGEPRILEASQRLQGHPEKYGKGEPKTES
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 KSSKFKSNSDSDYKGERINSSWEKETPGERSHSRVDSQSDKKLERQSERSQNINRKEVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSSKFKSNSDSDYKGERINSSWEKETPGERSHSRVDSQSDKKLERQSERSQNINRKEVKS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 QDKEERKVDQKPKSVVKDQDHWRRSERASLPHSKNEITFSHNSSKYHLEERRGWEDCKRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDKEERKVDQKPKSVVKDQDHWRRSERASLPHSKNEITFSHNSSKYHLEERRGWEDCKRD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 KSVNSHSFQDGRCPSSLSNSRTHKNIDSKEVDAMHQWENTPLKAERHRTEDKRKREQESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSVNSHSFQDGRCPSSLSNSRTHKNIDSKEVDAMHQWENTPLKAERHRTEDKRKREQESK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 EENRHIRNEKRVPTEHLQKTNKETKKTTTDLKKQNEPKTDKGEVLDNGVSEGADNKELAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EENRHIRNEKRVPTEHLQKTNKETKKTTTDLKKQNEPKTDKGEVLDNGVSEGADNKELAM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 KAESGPNETKNKDLKLSFMKKLNLTLSPAKKQPVSQDNQHKITDIPKSSGVCDSESSMQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAESGPNETKNKDLKLSFMKKLNLTLSPAKKQPVSQDNQHKITDIPKSSGVCDSESSMQV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 KTVAYVPSISEHILGEAAVSEHTMGETKSTLLEPKVALLAVTEPRIGISETNKEDENSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTVAYVPSISEHILGEAAVSEHTMGETKSTLLEPKVALLAVTEPRIGISETNKEDENSLL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 VRSVDNTMHCEEPICGTETSFPSPMEIQQTESLFPSTGMKQTINNGRAAAPVVMDVLQTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRSVDNTMHCEEPICGTETSFPSPMEIQQTESLFPSTGMKQTINNGRAAAPVVMDVLQTD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 VSQNFGLELDTKRNDNSDYCGISEGMEMKVALSTTVSETTESILQPSIEEADILPIMLSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSQNFGLELDTKRNDNSDYCGISEGMEMKVALSTTVSETTESILQPSIEEADILPIMLSE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 DNNPKFEPSVIVTPLVESKSCHLEPCLPKETLDSSLQQTELMDHRMATGETNSVYHDDDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNNPKFEPSVIVTPLVESKSCHLEPCLPKETLDSSLQQTELMDHRMATGETNSVYHDDDN
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA1 SVLSIDLNHLRPIPEAISPLNSPVRPVAKVLRNESPPQVPVYNNSHKDVFLPNSAHSTSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVLSIDLNHLRPIPEAISPLNSPVRPVAKVLRNESPPQVPVYNNSHKDVFLPNSAHSTSK
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA1 SQSDLNKENQKPIYKSDKCTEADTCKNSPLDELEEGEIRSDSETSKPQESFEKNSKRRVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQSDLNKENQKPIYKSDKCTEADTCKNSPLDELEEGEIRSDSETSKPQESFEKNSKRRVS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA1 ADVRKSKTIPRRGKSTVCLDKDSRKTHVRIHQTNNKWNKRPDKSSRSSKTEKKDKVMSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADVRKSKTIPRRGKSTVCLDKDSRKTHVRIHQTNNKWNKRPDKSSRSSKTEKKDKVMSTS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA1 SLEKIVPIIAVPSSEQEIMHMLRMIRKHVRKNYMKFKAKFSLIQFHRIIESAILSFTSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLEKIVPIIAVPSSEQEIMHMLRMIRKHVRKNYMKFKAKFSLIQFHRIIESAILSFTSLI
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA1 KHLNLHKISKSVTTLQKNLCDIIESKLKQVKKNGIVDRLFEQQLPDMKKKLWKFVDDQLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHLNLHKISKSVTTLQKNLCDIIESKLKQVKKNGIVDRLFEQQLPDMKKKLWKFVDDQLD
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA1 YLFAKLKKILVCDSKSFGRDSDEGKLEKTSKQNAQYSNSQKRSVDNSNRELLKEKLSKSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLFAKLKKILVCDSKSFGRDSDEGKLEKTSKQNAQYSNSQKRSVDNSNRELLKEKLSKSE
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA1 DPVHYKSLVGCKKSEENYQDQNNSSINTVKHDIKKNFNICFDNIKNSQSEERSLEVHCPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPVHYKSLVGCKKSEENYQDQNNSSINTVKHDIKKNFNICFDNIKNSQSEERSLEVHCPS
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA1 TPKSEKNEGSSIEDAQTSQHATLKPERSFEILTEQQASSLTFNLVSDAQMGEIFKSLLQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPKSEKNEGSSIEDAQTSQHATLKPERSFEILTEQQASSLTFNLVSDAQMGEIFKSLLQG
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA1 SDLLDSSVNCTEKSEWELKTPEKQLLETLKCESIPACTTEELVSGVASPCPKMISDDNWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDLLDSSVNCTEKSEWELKTPEKQLLETLKCESIPACTTEELVSGVASPCPKMISDDNWS
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA1 LLSSEKGPSLSSGLSLPVHPDVLDESCMFEVSTNLPLSKDNVCSVEKSKPCVSSILLEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLSSEKGPSLSSGLSLPVHPDVLDESCMFEVSTNLPLSKDNVCSVEKSKPCVSSILLEDL
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA1 AVSLTVPSPLKSDGHLSFLKPDMSSSSTPEEVISAHFSEDALLEEEDASEQDIHLALESD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVSLTVPSPLKSDGHLSFLKPDMSSSSTPEEVISAHFSEDALLEEEDASEQDIHLALESD
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA1 NSSSKSSCSSSWTSRSVAPGFQYHPNLPMHAVIMEKSNDHFIVKIRRATPSTSSGLKQSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSSSKSSCSSSWTSRSVAPGFQYHPNLPMHAVIMEKSNDHFIVKIRRATPSTSSGLKQSM
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KA1 MPDELLTSLPRHGKEADEGPEKEYISCQNTVFKSVEELENSNKNVDGSKSTHEEQSSMIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPDELLTSLPRHGKEADEGPEKEYISCQNTVFKSVEELENSNKNVDGSKSTHEEQSSMIQ
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KA1 TQVPDIYEFLKDASDKMGHSDEVADECFKLHQVWETKVPESIEELPSMEEISHSVGEHLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQVPDIYEFLKDASDKMGHSDEVADECFKLHQVWETKVPESIEELPSMEEISHSVGEHLP
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KA1 NTYVDLTKDPVTETKNLGEFIEVTVLHIDQLGCSGGNLNQSAQILDNSLQADTVGAFIDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTYVDLTKDPVTETKNLGEFIEVTVLHIDQLGCSGGNLNQSAQILDNSLQADTVGAFIDL
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790
pF1KA1 TQDASSEAKSEGN-PALAVEDLGCGVIQVDEDNCKEEKAQVANRPLKCIVEETYIDLTTE
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQDASSEAKSEGNHPALAVEDLGCGVIQVDEDNCKEEKAQVANRPLKCIVEETYIDLTTE
1750 1760 1770 1780 1790 1800
1800 1810 1820 1830 1840 1850
pF1KA1 SPSSCEVKKDELKSEPGSNCDNSELPGTLHNSHKKRRNISDLNHPHKKQRKETDLTNKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPSSCEVKKDELKSEPGSNCDNSELPGTLHNSHKKRRNISDLNHPHKKQRKETDLTNKEK
1810 1820 1830 1840 1850 1860
1860 1870 1880 1890 1900 1910
pF1KA1 TKKPTQDSCENTEAHQKKASKKKAPPVTKDPSSLKATPGIKDSSAALATSTSLSAKNVIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKKPTQDSCENTEAHQKKASKKKAPPVTKDPSSLKATPGIKDSSAALATSTSLSAKNVIK
1870 1880 1890 1900 1910 1920
1920 1930 1940 1950 1960 1970
pF1KA1 KKGEIIILWTRNDDREILLECQKRGPSFKTFAYLAAKLDKNPNQVSERFQQLMKLFEKSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKGEIIILWTRNDDREILLECQKRGPSFKTFAYLAAKLDKNPNQVSERFQQLMKLFEKSK
1930 1940 1950 1960 1970 1980
1980
pF1KA1 CR
::
NP_001 CR
>>NP_001131140 (OMIM: 606880) CASP8-associated protein 2 (1982 aa)
initn: 11467 init1: 11467 opt: 12958 Z-score: 8712.1 bits: 1625.5 E(85289): 0
Smith-Waterman score: 12958; 99.9% identity (99.9% similar) in 1982 aa overlap (1-1981:1-1982)
10 20 30 40 50 60
pF1KA1 MAADDDNGDGTSLFDVFSASPLKNNDEGSLDIYAGLDSAVSDSASKSCVPSRNCLDLYEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAADDDNGDGTSLFDVFSASPLKNNDEGSLDIYAGLDSAVSDSASKSCVPSRNCLDLYEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 ILTEEGTAKEATYNDLQVEYGKCQLQMKELMKKFKEIQTQNFSLINENQSLKKNISALIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILTEEGTAKEATYNDLQVEYGKCQLQMKELMKKFKEIQTQNFSLINENQSLKKNISALIK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 TARVEINRKDEEISNLHQRLSEFPHFRNNHKTARTFDTVKTKDLKSRSPHLDDCSKTDHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TARVEINRKDEEISNLHQRLSEFPHFRNNHKTARTFDTVKTKDLKSRSPHLDDCSKTDHR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 AKSDVSKDVHHSTSLPNLEKEGKPHSDKRSTSHLPTSVEKHCTNGVWSRSHYQVGEGSSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKSDVSKDVHHSTSLPNLEKEGKPHSDKRSTSHLPTSVEKHCTNGVWSRSHYQVGEGSSN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 EDSRRGRKDIRHSQFNRGTERVRKDLSTGCGDGEPRILEASQRLQGHPEKYGKGEPKTES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDSRRGRKDIRHSQFNRGTERVRKDLSTGCGDGEPRILEASQRLQGHPEKYGKGEPKTES
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 KSSKFKSNSDSDYKGERINSSWEKETPGERSHSRVDSQSDKKLERQSERSQNINRKEVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSSKFKSNSDSDYKGERINSSWEKETPGERSHSRVDSQSDKKLERQSERSQNINRKEVKS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 QDKEERKVDQKPKSVVKDQDHWRRSERASLPHSKNEITFSHNSSKYHLEERRGWEDCKRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDKEERKVDQKPKSVVKDQDHWRRSERASLPHSKNEITFSHNSSKYHLEERRGWEDCKRD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 KSVNSHSFQDGRCPSSLSNSRTHKNIDSKEVDAMHQWENTPLKAERHRTEDKRKREQESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSVNSHSFQDGRCPSSLSNSRTHKNIDSKEVDAMHQWENTPLKAERHRTEDKRKREQESK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 EENRHIRNEKRVPTEHLQKTNKETKKTTTDLKKQNEPKTDKGEVLDNGVSEGADNKELAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EENRHIRNEKRVPTEHLQKTNKETKKTTTDLKKQNEPKTDKGEVLDNGVSEGADNKELAM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 KAESGPNETKNKDLKLSFMKKLNLTLSPAKKQPVSQDNQHKITDIPKSSGVCDSESSMQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAESGPNETKNKDLKLSFMKKLNLTLSPAKKQPVSQDNQHKITDIPKSSGVCDSESSMQV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 KTVAYVPSISEHILGEAAVSEHTMGETKSTLLEPKVALLAVTEPRIGISETNKEDENSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTVAYVPSISEHILGEAAVSEHTMGETKSTLLEPKVALLAVTEPRIGISETNKEDENSLL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 VRSVDNTMHCEEPICGTETSFPSPMEIQQTESLFPSTGMKQTINNGRAAAPVVMDVLQTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRSVDNTMHCEEPICGTETSFPSPMEIQQTESLFPSTGMKQTINNGRAAAPVVMDVLQTD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 VSQNFGLELDTKRNDNSDYCGISEGMEMKVALSTTVSETTESILQPSIEEADILPIMLSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSQNFGLELDTKRNDNSDYCGISEGMEMKVALSTTVSETTESILQPSIEEADILPIMLSE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 DNNPKFEPSVIVTPLVESKSCHLEPCLPKETLDSSLQQTELMDHRMATGETNSVYHDDDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNNPKFEPSVIVTPLVESKSCHLEPCLPKETLDSSLQQTELMDHRMATGETNSVYHDDDN
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA1 SVLSIDLNHLRPIPEAISPLNSPVRPVAKVLRNESPPQVPVYNNSHKDVFLPNSAHSTSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVLSIDLNHLRPIPEAISPLNSPVRPVAKVLRNESPPQVPVYNNSHKDVFLPNSAHSTSK
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA1 SQSDLNKENQKPIYKSDKCTEADTCKNSPLDELEEGEIRSDSETSKPQESFEKNSKRRVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQSDLNKENQKPIYKSDKCTEADTCKNSPLDELEEGEIRSDSETSKPQESFEKNSKRRVS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA1 ADVRKSKTIPRRGKSTVCLDKDSRKTHVRIHQTNNKWNKRPDKSSRSSKTEKKDKVMSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADVRKSKTIPRRGKSTVCLDKDSRKTHVRIHQTNNKWNKRPDKSSRSSKTEKKDKVMSTS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA1 SLEKIVPIIAVPSSEQEIMHMLRMIRKHVRKNYMKFKAKFSLIQFHRIIESAILSFTSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLEKIVPIIAVPSSEQEIMHMLRMIRKHVRKNYMKFKAKFSLIQFHRIIESAILSFTSLI
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA1 KHLNLHKISKSVTTLQKNLCDIIESKLKQVKKNGIVDRLFEQQLPDMKKKLWKFVDDQLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHLNLHKISKSVTTLQKNLCDIIESKLKQVKKNGIVDRLFEQQLPDMKKKLWKFVDDQLD
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA1 YLFAKLKKILVCDSKSFGRDSDEGKLEKTSKQNAQYSNSQKRSVDNSNRELLKEKLSKSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLFAKLKKILVCDSKSFGRDSDEGKLEKTSKQNAQYSNSQKRSVDNSNRELLKEKLSKSE
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA1 DPVHYKSLVGCKKSEENYQDQNNSSINTVKHDIKKNFNICFDNIKNSQSEERSLEVHCPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPVHYKSLVGCKKSEENYQDQNNSSINTVKHDIKKNFNICFDNIKNSQSEERSLEVHCPS
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA1 TPKSEKNEGSSIEDAQTSQHATLKPERSFEILTEQQASSLTFNLVSDAQMGEIFKSLLQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPKSEKNEGSSIEDAQTSQHATLKPERSFEILTEQQASSLTFNLVSDAQMGEIFKSLLQG
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA1 SDLLDSSVNCTEKSEWELKTPEKQLLETLKCESIPACTTEELVSGVASPCPKMISDDNWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDLLDSSVNCTEKSEWELKTPEKQLLETLKCESIPACTTEELVSGVASPCPKMISDDNWS
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA1 LLSSEKGPSLSSGLSLPVHPDVLDESCMFEVSTNLPLSKDNVCSVEKSKPCVSSILLEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLSSEKGPSLSSGLSLPVHPDVLDESCMFEVSTNLPLSKDNVCSVEKSKPCVSSILLEDL
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA1 AVSLTVPSPLKSDGHLSFLKPDMSSSSTPEEVISAHFSEDALLEEEDASEQDIHLALESD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVSLTVPSPLKSDGHLSFLKPDMSSSSTPEEVISAHFSEDALLEEEDASEQDIHLALESD
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA1 NSSSKSSCSSSWTSRSVAPGFQYHPNLPMHAVIMEKSNDHFIVKIRRATPSTSSGLKQSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSSSKSSCSSSWTSRSVAPGFQYHPNLPMHAVIMEKSNDHFIVKIRRATPSTSSGLKQSM
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KA1 MPDELLTSLPRHGKEADEGPEKEYISCQNTVFKSVEELENSNKNVDGSKSTHEEQSSMIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPDELLTSLPRHGKEADEGPEKEYISCQNTVFKSVEELENSNKNVDGSKSTHEEQSSMIQ
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KA1 TQVPDIYEFLKDASDKMGHSDEVADECFKLHQVWETKVPESIEELPSMEEISHSVGEHLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQVPDIYEFLKDASDKMGHSDEVADECFKLHQVWETKVPESIEELPSMEEISHSVGEHLP
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KA1 NTYVDLTKDPVTETKNLGEFIEVTVLHIDQLGCSGGNLNQSAQILDNSLQADTVGAFIDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTYVDLTKDPVTETKNLGEFIEVTVLHIDQLGCSGGNLNQSAQILDNSLQADTVGAFIDL
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790
pF1KA1 TQDASSEAKSEGN-PALAVEDLGCGVIQVDEDNCKEEKAQVANRPLKCIVEETYIDLTTE
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQDASSEAKSEGNHPALAVEDLGCGVIQVDEDNCKEEKAQVANRPLKCIVEETYIDLTTE
1750 1760 1770 1780 1790 1800
1800 1810 1820 1830 1840 1850
pF1KA1 SPSSCEVKKDELKSEPGSNCDNSELPGTLHNSHKKRRNISDLNHPHKKQRKETDLTNKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPSSCEVKKDELKSEPGSNCDNSELPGTLHNSHKKRRNISDLNHPHKKQRKETDLTNKEK
1810 1820 1830 1840 1850 1860
1860 1870 1880 1890 1900 1910
pF1KA1 TKKPTQDSCENTEAHQKKASKKKAPPVTKDPSSLKATPGIKDSSAALATSTSLSAKNVIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKKPTQDSCENTEAHQKKASKKKAPPVTKDPSSLKATPGIKDSSAALATSTSLSAKNVIK
1870 1880 1890 1900 1910 1920
1920 1930 1940 1950 1960 1970
pF1KA1 KKGEIIILWTRNDDREILLECQKRGPSFKTFAYLAAKLDKNPNQVSERFQQLMKLFEKSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKGEIIILWTRNDDREILLECQKRGPSFKTFAYLAAKLDKNPNQVSERFQQLMKLFEKSK
1930 1940 1950 1960 1970 1980
1980
pF1KA1 CR
::
NP_001 CR
>>XP_016864545 (OMIM: 609268) PREDICTED: splicing regula (359 aa)
initn: 226 init1: 85 opt: 226 Z-score: 171.5 bits: 42.8 E(85289): 0.0082
Smith-Waterman score: 267; 22.5% identity (58.3% similar) in 386 aa overlap (165-544:4-358)
140 150 160 170 180 190
pF1KA1 NLHQRLSEFPHFRNNHKTARTFDTVKTKDLKSRSPHLDDCSKTDHRAKSDVSKDVHHSTS
.. . .:.. : ..:.: .: .. ..
XP_016 MTPQAAAKELEEVMKRVREAQSFISAAIEPESG
10 20 30
200 210 220 230 240 250
pF1KA1 LPNLEKEGKPHSDKRSTSHLPT---SVEKHCTNGVWSRSHYQVGEGSSNEDSRRGRKDIR
: .: :. .: :: :. . : .:. . :::: . : ..: ::...
XP_016 KSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNR--SRSRQKDRRRSKSP--
40 50 60 70 80
260 270 280 290 300 310
pF1KA1 HSQFNRGTERVRKDLSTGCGDGEPRILEASQRLQGHPEKYGKGEPKTESKSSKFKSNSDS
:.. ... :: ::. : . . . . .. .... :: : :.. . :
XP_016 HKKRSKSRER-RKSRSRSHSRDKRK--DTREKIK---EKERVKEKDREKEREREKEREKE
90 100 110 120 130 140
320 330 340 350 360 370
pF1KA1 DYKGERINSSWEKETPGERSHSRVDSQSDKKLERQSERSQNINRKEVKSQDKEERKVDQK
.:. . . :.: :. :...:.. ::..:. .. .... : ::::... .:
XP_016 KERGKNKDRDKEREKDREK-----DKEKDREREREKEHEKDRDKEKEKEQDKEKER--EK
150 160 170 180 190
380 390 400 410 420
pF1KA1 PKSVVKDQDHWRRSERASL--PHSKNEITFSHNSSKYHLEERRGWEDCKRDKSVNSHSFQ
.: :. :. :.... : :.: : :..::. . ..::. . . .. .. . .
XP_016 DRS--KEIDEKRKKDKKSRTPPRSYNASRRSRSSSRER-RRRRSRSSSRSPRTSKTIKRK
200 210 220 230 240 250
430 440 450 460 470 480
pF1KA1 DGRCPSSLSNSRTHKNIDSKEVDAMHQWENTPLKAERHRTEDKRKREQESKEENRHIRNE
..: :: : .. :. . :: : . . . ::.:. . :: :.... . . :
XP_016 SSRSPSPRSRNKKDKKRE-KERDHISE------RRERERSTSMRKS---SNDRDGKEKLE
260 270 280 290 300
490 500 510 520 530 540
pF1KA1 KRVPTEHLQKTNKETKKTTT-DLKKQNEPKTDKGEVLDNGVSEGADNKELAMKAESGPNE
: . . .. ::: .... .. .. :.:..... :: . ....:. :.:.
XP_016 KNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQ-LNEENLSTKTEAV
310 320 330 340 350
550 560 570 580 590 600
pF1KA1 TKNKDLKLSFMKKLNLTLSPAKKQPVSQDNQHKITDIPKSSGVCDSESSMQVKTVAYVPS
>>NP_001310463 (OMIM: 609268) splicing regulatory glutam (359 aa)
initn: 226 init1: 85 opt: 226 Z-score: 171.5 bits: 42.8 E(85289): 0.0082
Smith-Waterman score: 267; 22.5% identity (58.3% similar) in 386 aa overlap (165-544:4-358)
140 150 160 170 180 190
pF1KA1 NLHQRLSEFPHFRNNHKTARTFDTVKTKDLKSRSPHLDDCSKTDHRAKSDVSKDVHHSTS
.. . .:.. : ..:.: .: .. ..
NP_001 MTPQAAAKELEEVMKRVREAQSFISAAIEPESG
10 20 30
200 210 220 230 240 250
pF1KA1 LPNLEKEGKPHSDKRSTSHLPT---SVEKHCTNGVWSRSHYQVGEGSSNEDSRRGRKDIR
: .: :. .: :: :. . : .:. . :::: . : ..: ::...
NP_001 KSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNR--SRSRQKDRRRSKSP--
40 50 60 70 80
260 270 280 290 300 310
pF1KA1 HSQFNRGTERVRKDLSTGCGDGEPRILEASQRLQGHPEKYGKGEPKTESKSSKFKSNSDS
:.. ... :: ::. : . . . . .. .... :: : :.. . :
NP_001 HKKRSKSRER-RKSRSRSHSRDKRK--DTREKIK---EKERVKEKDREKEREREKEREKE
90 100 110 120 130 140
320 330 340 350 360 370
pF1KA1 DYKGERINSSWEKETPGERSHSRVDSQSDKKLERQSERSQNINRKEVKSQDKEERKVDQK
.:. . . :.: :. :...:.. ::..:. .. .... : ::::... .:
NP_001 KERGKNKDRDKEREKDREK-----DKEKDREREREKEHEKDRDKEKEKEQDKEKER--EK
150 160 170 180 190
380 390 400 410 420
pF1KA1 PKSVVKDQDHWRRSERASL--PHSKNEITFSHNSSKYHLEERRGWEDCKRDKSVNSHSFQ
.: :. :. :.... : :.: : :..::. . ..::. . . .. .. . .
NP_001 DRS--KEIDEKRKKDKKSRTPPRSYNASRRSRSSSRER-RRRRSRSSSRSPRTSKTIKRK
200 210 220 230 240 250
430 440 450 460 470 480
pF1KA1 DGRCPSSLSNSRTHKNIDSKEVDAMHQWENTPLKAERHRTEDKRKREQESKEENRHIRNE
..: :: : .. :. . :: : . . . ::.:. . :: :.... . . :
NP_001 SSRSPSPRSRNKKDKKRE-KERDHISE------RRERERSTSMRKS---SNDRDGKEKLE
260 270 280 290 300
490 500 510 520 530 540
pF1KA1 KRVPTEHLQKTNKETKKTTT-DLKKQNEPKTDKGEVLDNGVSEGADNKELAMKAESGPNE
: . . .. ::: .... .. .. :.:..... :: . ....:. :.:.
NP_001 KNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQ-LNEENLSTKTEAV
310 320 330 340 350
550 560 570 580 590 600
pF1KA1 TKNKDLKLSFMKKLNLTLSPAKKQPVSQDNQHKITDIPKSSGVCDSESSMQVKTVAYVPS
1981 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 19:59:14 2016 done: Thu Nov 3 19:59:17 2016
Total Scan time: 19.190 Total Display time: 0.490
Function used was FASTA [36.3.4 Apr, 2011]