FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA1162, 349 aa
  1>>>pF1KA1162 349 - 349 aa - 349 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.2003+/-0.000371; mu= -1.8994+/- 0.023
 mean_var=245.1512+/-48.666, 0's: 0 Z-trim(121.9): 11  B-trim: 650 in 2/51
 Lambda= 0.081914
 statistics sampled from 39291 (39303) to 39291 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.79), E-opt: 0.2 (0.461), width:  16
 Scan time:  9.740

The best scores are:                                      opt bits E(85289)
NP_066979 (OMIM: 616766) thioredoxin-related trans ( 349) 2371 292.9   7e-79
NP_110382 (OMIM: 610527) thioredoxin-related trans ( 280)  726 98.4   2e-20


>>NP_066979 (OMIM: 616766) thioredoxin-related transmemb  (349 aa)
 initn: 2371 init1: 2371 opt: 2371  Z-score: 1537.2  bits: 292.9 E(85289): 7e-79
Smith-Waterman score: 2371; 100.0% identity (100.0% similar) in 349 aa overlap (1-349:1-349)

               10        20        30        40        50        60
pF1KA1 MAGGRCGPQLTALLAAWIAAVAATAGPEEAALPPEQSRVQPMTASNWTLVMEGEWMLKFY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 MAGGRCGPQLTALLAAWIAAVAATAGPEEAALPPEQSRVQPMTASNWTLVMEGEWMLKFY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 APWCPSCQQTDSEWEAFAKNGEILQISVGKVDVIQEPGLSGRFFVTTLPAFFHAKDGIFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 APWCPSCQQTDSEWEAFAKNGEILQISVGKVDVIQEPGLSGRFFVTTLPAFFHAKDGIFR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 RYRGPGIFEDLQNYILEKKWQSVEPLTGWKSPASLTMSGMAGLFSISGKIWHLHNYFTVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 RYRGPGIFEDLQNYILEKKWQSVEPLTGWKSPASLTMSGMAGLFSISGKIWHLHNYFTVT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 LGIPAWCSYVFFVIATLVFGLFMGLVLVVISECFYVPLPRHLSERSEQNRRSEEAHRAEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 LGIPAWCSYVFFVIATLVFGLFMGLVLVVISECFYVPLPRHLSERSEQNRRSEEAHRAEQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 LQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEEDNLAAGVDEERSEANDQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 LQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEEDNLAAGVDEERSEANDQG
              250       260       270       280       290       300

              310       320       330       340         
pF1KA1 PPGEDGVTREEVEPEEAEEGISEQPCPADTEVVEDSLRQRKSQHADKGL
       :::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 PPGEDGVTREEVEPEEAEEGISEQPCPADTEVVEDSLRQRKSQHADKGL
              310       320       330       340         

>>NP_110382 (OMIM: 610527) thioredoxin-related transmemb  (280 aa)
 initn: 787 init1: 687 opt: 726  Z-score: 487.8  bits: 98.4 E(85289): 2e-20
Smith-Waterman score: 736; 44.0% identity (74.8% similar) in 234 aa overlap (36-258:28-260)

          10        20        30        40        50        60     
pF1KA1 CGPQLTALLAAWIAAVAATAGPEEAALPPEQSRVQPMTASNWTLVMEGEWMLKFYAPWCP
                                     .: :. .:  ::  ..::.::..:::::::
NP_110    MAPSGSLAVPLAVLVLLLWGAPWTHGRRSNVRVITDENWRELLEGDWMIEFYAPWCP
                  10        20        30        40        50       

          70        80        90       100       110       120     
pF1KA1 SCQQTDSEWEAFAKNGEILQISVGKVDVIQEPGLSGRFFVTTLPAFFHAKDGIFRRYRGP
       .::. . :::.::. :: :.....:::: ..:::::::..:.::...: ::: ::::.::
NP_110 ACQNLQPEWESFAEWGEDLEVNIAKVDVTEQPGLSGRFIITALPTIYHCKDGEFRRYQGP
        60        70        80        90       100       110       

         130       140       150       160       170       180     
pF1KA1 GIFEDLQNYILEKKWQSVEPLTGWKSPASLTMSGMAGLFSISGKIWHLHNYFTVTLGIPA
          .:. :.: .:.:.:.::...: .:.:. ::.:..::..:  :   ::::   ::.:.
NP_110 RTKKDFINFISDKEWKSIEPVSSWFGPGSVLMSSMSALFQLSMWIRTCHNYFIEDLGLPV
       120       130       140       150       160       170       

         190       200       210                  220       230    
pF1KA1 WCSYVFFVIATLVFGLFMGLVLVVISECFY---------VPLP--RHLSERSEQNRRSEE
       : ::. :..:::  ::..:: .. ...:.           : :  . ::: ..  .. ::
NP_110 WGSYTVFALATLFSGLLLGLCMIFVADCLCPSKRRRPQPYPYPSKKLLSESAQPLKKVEE
       180       190       200       210       220       230       

          240       250       260       270       280       290    
pF1KA1 AHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEEDNLAAGVDEERS
        ..:.. .:. ::. .:.:  :::                                    
NP_110 EQEADE-EDVSEEEAESKEGTNKDFPQNAIRQRSLGPSLATDKS                
       240        250       260       270       280                




349 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 01:22:00 2016 done: Fri Nov  4 01:22:02 2016
 Total Scan time:  9.740 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]