Result of FASTA (ccds) for
pF1KA0834
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0834, 451 aa
1>>>pF1KA0834 451 - 451 aa - 451 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.1969+/-0.00125; mu= 2.8439+/- 0.072
mean_var=265.3687+/-63.252, 0's: 0 Z-trim(107.9): 650 B-trim: 0 in 0/49
Lambda= 0.078732
statistics sampled from 9126 (9887) to 9126 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.668), E-opt: 0.2 (0.304), width: 16
Scan time: 2.060
The best scores are: opt bits E(32554)
CCDS5619.1 CDK14 gene_id:5218|Hs108|chr7 ( 451) 3031 358.5 8.2e-99
CCDS75626.1 CDK14 gene_id:5218|Hs108|chr7 ( 469) 2864 339.5 4.3e-93
CCDS75627.1 CDK14 gene_id:5218|Hs108|chr7 ( 423) 2828 335.4 6.9e-92
CCDS75628.1 CDK14 gene_id:5218|Hs108|chr7 ( 340) 2111 253.8 2e-67
CCDS2350.1 CDK15 gene_id:65061|Hs108|chr2 ( 384) 1535 188.4 1.1e-47
CCDS58747.1 CDK15 gene_id:65061|Hs108|chr2 ( 429) 1498 184.3 2.1e-46
CCDS58746.1 CDK15 gene_id:65061|Hs108|chr2 ( 400) 1473 181.4 1.4e-45
CCDS14276.1 CDK16 gene_id:5127|Hs108|chrX ( 496) 1237 154.7 1.9e-37
CCDS48101.1 CDK16 gene_id:5127|Hs108|chrX ( 502) 1237 154.7 1.9e-37
CCDS9061.1 CDK17 gene_id:5128|Hs108|chr12 ( 523) 1237 154.8 2e-37
CCDS55408.1 CDK16 gene_id:5127|Hs108|chrX ( 570) 1237 154.8 2.1e-37
CCDS53819.1 CDK17 gene_id:5128|Hs108|chr12 ( 523) 1234 154.4 2.5e-37
CCDS44300.1 CDK18 gene_id:5129|Hs108|chr1 ( 474) 1227 153.6 4.1e-37
CCDS1454.1 CDK18 gene_id:5129|Hs108|chr1 ( 504) 1227 153.6 4.3e-37
CCDS47748.1 CDK5 gene_id:1020|Hs108|chr7 ( 292) 1037 131.7 9.4e-31
CCDS11736.1 CDK3 gene_id:1018|Hs108|chr17 ( 305) 1003 127.9 1.4e-29
CCDS8898.1 CDK2 gene_id:1017|Hs108|chr12 ( 298) 966 123.7 2.6e-28
CCDS44408.1 CDK1 gene_id:983|Hs108|chr10 ( 297) 918 118.2 1.1e-26
CCDS72682.1 CDK11B gene_id:984|Hs108|chr1 ( 748) 774 102.3 1.7e-21
CCDS72684.1 CDK11B gene_id:984|Hs108|chr1 ( 782) 774 102.4 1.8e-21
CCDS72683.1 CDK11B gene_id:984|Hs108|chr1 ( 795) 774 102.4 1.8e-21
CCDS3999.1 CDK7 gene_id:1022|Hs108|chr5 ( 346) 764 100.8 2.3e-21
CCDS44043.1 CDK11A gene_id:728642|Hs108|chr1 ( 770) 765 101.3 3.5e-21
CCDS81254.1 CDK11A gene_id:728642|Hs108|chr1 ( 779) 765 101.3 3.6e-21
CCDS44042.1 CDK11A gene_id:728642|Hs108|chr1 ( 780) 765 101.3 3.6e-21
CCDS81253.1 CDK11A gene_id:728642|Hs108|chr1 ( 783) 765 101.3 3.6e-21
CCDS10984.2 CDK10 gene_id:8558|Hs108|chr16 ( 360) 735 97.5 2.3e-20
CCDS35060.1 CDK20 gene_id:23552|Hs108|chr9 ( 346) 643 87.1 3.1e-17
CCDS32514.2 CDK10 gene_id:8558|Hs108|chr16 ( 272) 633 85.8 5.9e-17
CCDS47265.1 CDKL3 gene_id:51265|Hs108|chr5 ( 455) 629 85.6 1.1e-16
CCDS47264.1 CDKL3 gene_id:51265|Hs108|chr5 ( 592) 629 85.8 1.3e-16
CCDS3570.1 CDKL2 gene_id:8999|Hs108|chr4 ( 493) 625 85.2 1.6e-16
CCDS75398.1 MAK gene_id:4117|Hs108|chr6 ( 583) 626 85.4 1.7e-16
CCDS5628.1 CDK6 gene_id:1021|Hs108|chr7 ( 326) 621 84.5 1.7e-16
CCDS4516.1 MAK gene_id:4117|Hs108|chr6 ( 623) 626 85.4 1.7e-16
CCDS82933.1 CDKL2 gene_id:8999|Hs108|chr4 ( 570) 625 85.3 1.8e-16
CCDS75399.1 MAK gene_id:4117|Hs108|chr6 ( 648) 626 85.5 1.8e-16
CCDS4949.1 ICK gene_id:22858|Hs108|chr6 ( 632) 609 83.5 6.7e-16
CCDS33184.1 CDKL4 gene_id:344387|Hs108|chr2 ( 315) 600 82.1 8.7e-16
CCDS9699.1 CDKL1 gene_id:8814|Hs108|chr14 ( 358) 592 81.3 1.8e-15
CCDS83458.1 CDKL5 gene_id:6792|Hs108|chrX ( 960) 598 82.5 2.1e-15
CCDS14186.1 CDKL5 gene_id:6792|Hs108|chrX (1030) 598 82.5 2.2e-15
CCDS13795.1 MAPK1 gene_id:5594|Hs108|chr22 ( 360) 585 80.5 3.1e-15
CCDS8899.1 CDK2 gene_id:1017|Hs108|chr12 ( 264) 579 79.7 4e-15
CCDS42149.1 MAPK3 gene_id:5595|Hs108|chr16 ( 357) 579 79.8 4.9e-15
CCDS10672.1 MAPK3 gene_id:5595|Hs108|chr16 ( 379) 579 79.8 5.1e-15
CCDS6879.1 CDK9 gene_id:1025|Hs108|chr9 ( 372) 578 79.7 5.5e-15
CCDS73637.1 CDKL1 gene_id:8814|Hs108|chr14 ( 276) 568 78.4 9.9e-15
CCDS11206.1 MAPK7 gene_id:5598|Hs108|chr17 ( 816) 572 79.4 1.5e-14
CCDS55184.1 CDK5 gene_id:1020|Hs108|chr7 ( 260) 555 76.9 2.6e-14
>>CCDS5619.1 CDK14 gene_id:5218|Hs108|chr7 (451 aa)
initn: 3031 init1: 3031 opt: 3031 Z-score: 1887.4 bits: 358.5 E(32554): 8.2e-99
Smith-Waterman score: 3031; 100.0% identity (100.0% similar) in 451 aa overlap (1-451:1-451)
10 20 30 40 50 60
pF1KA0 MHGYFGCNAAAEPGYSAFVGTPQICVTKMSTRNCQGMDSVIKPLDTIPEDKKVRVQRTQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MHGYFGCNAAAEPGYSAFVGTPQICVTKMSTRNCQGMDSVIKPLDTIPEDKKVRVQRTQS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 TFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 TFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 EKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 EKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 IIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 IIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 PQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 PQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 GCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 GCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 LRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 LRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTV
370 380 390 400 410 420
430 440 450
pF1KA0 PNVRLQPEAGESMRAFGKNNSYGKSLSNSKH
:::::::::::::::::::::::::::::::
CCDS56 PNVRLQPEAGESMRAFGKNNSYGKSLSNSKH
430 440 450
>>CCDS75626.1 CDK14 gene_id:5218|Hs108|chr7 (469 aa)
initn: 2864 init1: 2864 opt: 2864 Z-score: 1784.7 bits: 339.5 E(32554): 4.3e-93
Smith-Waterman score: 2864; 99.8% identity (100.0% similar) in 429 aa overlap (23-451:41-469)
10 20 30 40 50
pF1KA0 MHGYFGCNAAAEPGYSAFVGTPQICVTKMSTRNCQGMDSVIKPLDTIPEDKK
.:::::::::::::::::::::::::::::
CCDS75 EKIGKMKKLRRTLSESFSRIALKKDDTTFDEICVTKMSTRNCQGMDSVIKPLDTIPEDKK
20 30 40 50 60 70
60 70 80 90 100 110
pF1KA0 VRVQRTQSTFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 VRVQRTQSTFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFG
80 90 100 110 120 130
120 130 140 150 160 170
pF1KA0 KADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 KADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKH
140 150 160 170 180 190
180 190 200 210 220 230
pF1KA0 ANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 ANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQR
200 210 220 230 240 250
240 250 260 270 280 290
pF1KA0 YILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 YILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYS
260 270 280 290 300 310
300 310 320 330 340 350
pF1KA0 TCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 TCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPER
320 330 340 350 360 370
360 370 380 390 400 410
pF1KA0 FTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 FTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELT
380 390 400 410 420 430
420 430 440 450
pF1KA0 DMSSIFTVPNVRLQPEAGESMRAFGKNNSYGKSLSNSKH
:::::::::::::::::::::::::::::::::::::::
CCDS75 DMSSIFTVPNVRLQPEAGESMRAFGKNNSYGKSLSNSKH
440 450 460
>>CCDS75627.1 CDK14 gene_id:5218|Hs108|chr7 (423 aa)
initn: 2828 init1: 2828 opt: 2828 Z-score: 1763.1 bits: 335.4 E(32554): 6.9e-92
Smith-Waterman score: 2828; 100.0% identity (100.0% similar) in 423 aa overlap (29-451:1-423)
10 20 30 40 50 60
pF1KA0 MHGYFGCNAAAEPGYSAFVGTPQICVTKMSTRNCQGMDSVIKPLDTIPEDKKVRVQRTQS
::::::::::::::::::::::::::::::::
CCDS75 MSTRNCQGMDSVIKPLDTIPEDKKVRVQRTQS
10 20 30
70 80 90 100 110 120
pF1KA0 TFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 TFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKL
40 50 60 70 80 90
130 140 150 160 170 180
pF1KA0 EKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 EKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHD
100 110 120 130 140 150
190 200 210 220 230 240
pF1KA0 IIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 IIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLK
160 170 180 190 200 210
250 260 270 280 290 300
pF1KA0 PQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 PQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGV
220 230 240 250 260 270
310 320 330 340 350 360
pF1KA0 GCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 GCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKN
280 290 300 310 320 330
370 380 390 400 410 420
pF1KA0 LRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 LRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTV
340 350 360 370 380 390
430 440 450
pF1KA0 PNVRLQPEAGESMRAFGKNNSYGKSLSNSKH
:::::::::::::::::::::::::::::::
CCDS75 PNVRLQPEAGESMRAFGKNNSYGKSLSNSKH
400 410 420
>>CCDS75628.1 CDK14 gene_id:5218|Hs108|chr7 (340 aa)
initn: 2111 init1: 2111 opt: 2111 Z-score: 1324.1 bits: 253.8 E(32554): 2e-67
Smith-Waterman score: 2111; 99.4% identity (100.0% similar) in 316 aa overlap (136-451:25-340)
110 120 130 140 150 160
pF1KA0 PTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREAS
..::::::::::::::::::::::::::::
CCDS75 MLALTLRPPPLAKSHLKLGGTPAPARVNGKLVALKVIRLQEEEGTPFTAIREAS
10 20 30 40 50
170 180 190 200 210 220
pF1KA0 LLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 LLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRG
60 70 80 90 100 110
230 240 250 260 270 280
pF1KA0 LSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 LSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVL
120 130 140 150 160 170
290 300 310 320 330 340
pF1KA0 LGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 LGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSL
180 190 200 210 220 230
350 360 370 380 390 400
pF1KA0 PHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 PHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLP
240 250 260 270 280 290
410 420 430 440 450
pF1KA0 PRLWELTDMSSIFTVPNVRLQPEAGESMRAFGKNNSYGKSLSNSKH
::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 PRLWELTDMSSIFTVPNVRLQPEAGESMRAFGKNNSYGKSLSNSKH
300 310 320 330 340
>>CCDS2350.1 CDK15 gene_id:65061|Hs108|chr2 (384 aa)
initn: 1529 init1: 1529 opt: 1535 Z-score: 969.9 bits: 188.4 E(32554): 1.1e-47
Smith-Waterman score: 1535; 67.9% identity (88.5% similar) in 330 aa overlap (111-440:46-375)
90 100 110 120 130 140
pF1KA0 ACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNG
:: :.:: .::::::::::::::: :..::
CCDS23 KFKSKRPRSNSDCFQEEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRING
20 30 40 50 60 70
150 160 170 180 190 200
pF1KA0 KLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLC
.::::::: .. :::.:::::::::::::::::::::::::::::::::.::::.::::
CCDS23 QLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLA
80 90 100 110 120 130
210 220 230 240 250 260
pF1KA0 QYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLA
:::..::::::: ::.::.:::::::.:::....::::::::::::: :::::::::::
CCDS23 QYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLA
140 150 160 170 180 190
270 280 290 300 310 320
pF1KA0 RAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDI
::::.::.:::.:::::::::::.:::.::::. ::.::.::::.::.:: :::...:
CCDS23 RAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNI
200 210 220 230 240 250
330 340 350 360 370 380
pF1KA0 QDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASK
.:::.:. :::.:.::::::: .::...:: : : . ..:. .::.:. : .::::::.
CCDS23 LEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPEAEDLASQ
260 270 280 290 300 310
390 400 410 420 430 440
pF1KA0 LLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRAFGKNN
.:. :..:.::: :: :.::: :: .:..: : :.::: .:::.:: . . .. :..
CCDS23 MLKGFPRDRVSAQEALVHDYFSALPSQLYQLPDEESLFTVSGVRLKPEMCDLLASYQKGH
320 330 340 350 360 370
450
pF1KA0 SYGKSLSNSKH
CCDS23 HPAQFSKCW
380
>>CCDS58747.1 CDK15 gene_id:65061|Hs108|chr2 (429 aa)
initn: 1483 init1: 1483 opt: 1498 Z-score: 946.6 bits: 184.3 E(32554): 2.1e-46
Smith-Waterman score: 1499; 59.7% identity (81.4% similar) in 387 aa overlap (58-440:51-420)
30 40 50 60 70 80
pF1KA0 KMSTRNCQGMDSVIKPLDTIPEDKKVRVQRTQSTFDPFEKPANQVKRVHSE----NNACI
....: : : .... .:. :. :.
CCDS58 EGGEAHSCRRSQPETTEAAFKLTDLKEASCSMTSFHPRGLQAARAQKFKSKRPRSNSDCF
30 40 50 60 70 80
90 100 110 120 130 140
pF1KA0 NFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLV
. . : . :.: : :: :.:: .::::::::::::::: :..::.::
CCDS58 QEEDLRQGFQ----WRKSLP-------FGAASSYLNLEKLGEGSYATVYKGISRINGQLV
90 100 110 120
150 160 170 180 190 200
pF1KA0 ALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYM
::::: .. :::.:::::::::::::::::::::::::::::::::.::::.:::: :::
CCDS58 ALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLAQYM
130 140 150 160 170 180
210 220 230 240 250 260
pF1KA0 DKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAK
..::::::: ::.::.:::::::.:::....::::::::::::: ::::::::::::::
CCDS58 SQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAK
190 200 210 220 230 240
270 280 290 300 310 320
pF1KA0 SVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQ
:.::.:::.:::::::::::.:::.::::. ::.::.::::.::.:: :::...: .:
CCDS58 SIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQ
250 260 270 280 290 300
330 340 350 360 370 380
pF1KA0 LERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQ
::.:. :::.:.::::::: .::...:: : : . ..:. .::.:. : .::::::..:.
CCDS58 LEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPEAEDLASQMLK
310 320 330 340 350 360
390 400 410 420 430 440
pF1KA0 CSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRAFGKNNSYG
:..:.::: :: :.::: :: .:..: :.:. :::.:: . . .. :..
CCDS58 GFPRDRVSAQEALVHDYFSALPSQLYQLPDVSG------VRLKPEMCDLLASYQKGHHPA
370 380 390 400 410 420
450
pF1KA0 KSLSNSKH
CCDS58 QFSKCW
>>CCDS58746.1 CDK15 gene_id:65061|Hs108|chr2 (400 aa)
initn: 1473 init1: 1473 opt: 1473 Z-score: 931.6 bits: 181.4 E(32554): 1.4e-45
Smith-Waterman score: 1474; 62.2% identity (83.1% similar) in 360 aa overlap (58-413:51-399)
30 40 50 60 70 80
pF1KA0 KMSTRNCQGMDSVIKPLDTIPEDKKVRVQRTQSTFDPFEKPANQVKRVHSE----NNACI
....: : : .... .:. :. :.
CCDS58 EGGEAHSCRRSQPETTEAAFKLTDLKEASCSMTSFHPRGLQAARAQKFKSKRPRSNSDCF
30 40 50 60 70 80
90 100 110 120 130 140
pF1KA0 NFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLV
. . : . :.: : :: :.:: .::::::::::::::: :..::.::
CCDS58 QEEDLRQGFQ----WRKSLP-------FGAASSYLNLEKLGEGSYATVYKGISRINGQLV
90 100 110 120
150 160 170 180 190 200
pF1KA0 ALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYM
::::: .. :::.:::::::::::::::::::::::::::::::::.::::.:::: :::
CCDS58 ALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLAQYM
130 140 150 160 170 180
210 220 230 240 250 260
pF1KA0 DKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAK
..::::::: ::.::.:::::::.:::....::::::::::::: ::::::::::::::
CCDS58 SQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAK
190 200 210 220 230 240
270 280 290 300 310 320
pF1KA0 SVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQ
:.::.:::.:::::::::::.:::.::::. ::.::.::::.::.:: :::...: .:
CCDS58 SIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQ
250 260 270 280 290 300
330 340 350 360 370 380
pF1KA0 LERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQ
::.:. :::.:.::::::: .::...:: : : . ..:. .::.:. : .::::::..:.
CCDS58 LEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPEAEDLASQMLK
310 320 330 340 350 360
390 400 410 420 430 440
pF1KA0 CSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRAFGKNNSYG
:..:.::: :: :.::: :: .:..: :
CCDS58 GFPRDRVSAQEALVHDYFSALPSQLYQLPDE
370 380 390 400
>>CCDS14276.1 CDK16 gene_id:5127|Hs108|chrX (496 aa)
initn: 1229 init1: 983 opt: 1237 Z-score: 785.7 bits: 154.7 E(32554): 1.9e-37
Smith-Waterman score: 1237; 59.7% identity (80.3% similar) in 325 aa overlap (111-435:159-478)
90 100 110 120 130 140
pF1KA0 ACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNG
::: ..: ::.:::::.::::::::::..
CCDS14 GYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTD
130 140 150 160 170 180
150 160 170 180 190 200
pF1KA0 KLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLC
.::::: :::..:::.: :::::.:::: ::::::: :::::::...:::::::. ::
CCDS14 NLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLK
190 200 210 220 230 240
210 220 230 240 250 260
pF1KA0 QYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLA
::.: . .. :::::::::::::.: :.. .::::::::::::.. :::::::::::
CCDS14 QYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLA
250 260 270 280 290 300
270 280 290 300 310 320
pF1KA0 RAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDI
::::.:..:::::::::::::::.:::::.::: .::::::::: :: : ::: . .
CCDS14 RAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPG-STV
310 320 330 340 350 360
330 340 350 360 370 380
pF1KA0 QDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASK
..::. :: .::::.:.::::. : .:: . : .. : . .:. . . :: .:
CCDS14 EEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLD--SDGADLLTK
370 380 390 400 410 420
390 400 410 420 430 440
pF1KA0 LLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRAFGKNN
::: .::.::. :..: .: .: :. .: : .:::.. ...:: :: :.:.
CCDS14 LLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEA--SLRSSSMPD
430 440 450 460 470 480
450
pF1KA0 SYGKSLSNSKH
CCDS14 SGRPAFRVVDTEF
490
>>CCDS48101.1 CDK16 gene_id:5127|Hs108|chrX (502 aa)
initn: 1229 init1: 983 opt: 1237 Z-score: 785.6 bits: 154.7 E(32554): 1.9e-37
Smith-Waterman score: 1237; 59.7% identity (80.3% similar) in 325 aa overlap (111-435:165-484)
90 100 110 120 130 140
pF1KA0 ACINFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNG
::: ..: ::.:::::.::::::::::..
CCDS48 GYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTD
140 150 160 170 180 190
150 160 170 180 190 200
pF1KA0 KLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLC
.::::: :::..:::.: :::::.:::: ::::::: :::::::...:::::::. ::
CCDS48 NLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLK
200 210 220 230 240 250
210 220 230 240 250 260
pF1KA0 QYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLA
::.: . .. :::::::::::::.: :.. .::::::::::::.. :::::::::::
CCDS48 QYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLA
260 270 280 290 300 310
270 280 290 300 310 320
pF1KA0 RAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDI
::::.:..:::::::::::::::.:::::.::: .::::::::: :: : ::: . .
CCDS48 RAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPG-STV
320 330 340 350 360 370
330 340 350 360 370 380
pF1KA0 QDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASK
..::. :: .::::.:.::::. : .:: . : .. : . .:. . . :: .:
CCDS48 EEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLD--SDGADLLTK
380 390 400 410 420 430
390 400 410 420 430 440
pF1KA0 LLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRAFGKNN
::: .::.::. :..: .: .: :. .: : .:::.. ...:: :: :.:.
CCDS48 LLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEA--SLRSSSMPD
440 450 460 470 480
450
pF1KA0 SYGKSLSNSKH
CCDS48 SGRPAFRVVDTEF
490 500
>>CCDS9061.1 CDK17 gene_id:5128|Hs108|chr12 (523 aa)
initn: 1202 init1: 986 opt: 1237 Z-score: 785.4 bits: 154.8 E(32554): 2e-37
Smith-Waterman score: 1237; 51.8% identity (74.5% similar) in 396 aa overlap (54-449:131-520)
30 40 50 60 70 80
pF1KA0 ICVTKMSTRNCQGMDSVIKPLDTIPEDKKVRVQRTQSTFDPFEKPANQVKRVHSENNACI
:..: : : ..: . .. ..
CCDS90 LKMGSDGESDQASGTSSDEVQSPTGVCLRNRIHRRISMED-LNKRLSLPADIRIPDGYLE
110 120 130 140 150
90 100 110 120 130 140
pF1KA0 NFKTSSTGKESPKVRRHSSPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLV
... .: ..: :: : .: . ::: ..: ::::::::.:::::::.::.. .::
CCDS90 KLQINSPPFDQPMSRR-SRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLV
160 170 180 190 200 210
150 160 170 180 190 200
pF1KA0 ALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYM
::: :::..:::.: :::::.:::: ::::::: ::::.:: ..:::::::. :: :::
CCDS90 ALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYM
220 230 240 250 260 270
210 220 230 240 250 260
pF1KA0 DKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAK
: . . ::::::.:.::::.: :.: .::::::::::::.. ::::::::::::::
CCDS90 DDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAK
280 290 300 310 320 330
270 280 290 300 310 320
pF1KA0 SVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQ
:::..::::::::::::::::::::.:::: .::::::::: :: .: ::: . ..:.
CCDS90 SVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPG-STVEDE
340 350 360 370 380 390
330 340 350 360 370 380
pF1KA0 LERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQ
:. :: .::::...::::. : .:: : :. . : . .:. ... .: .:.::
CCDS90 LHLIFRLLGTPSQETWPGISSNEEFKNYNFPKYKPQPLINHAPRLD--SEGIELITKFLQ
400 410 420 430 440 450
390 400 410 420 430 440
pF1KA0 CSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRAFGKNNSYG
:.:.::. :..: :: .: ::. : . :::.. ...:: . : .. ... .:
CCDS90 YESKKRVSAEEAMKHVYFRSLGPRIHALPESVSIFSLKEIQLQKDPGFRNSSYPETG-HG
460 470 480 490 500 510
450
pF1KA0 KSLSNSKH
:. .:
CCDS90 KNRRQSMLF
520
451 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 19:49:38 2016 done: Wed Nov 2 19:49:39 2016
Total Scan time: 2.060 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]