Result of FASTA (omim) for
pF1KA0808
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0808, 526 aa
1>>>pF1KA0808 526 - 526 aa - 526 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.0985+/-0.000357; mu= -7.8221+/- 0.022
mean_var=303.6393+/-63.748, 0's: 0 Z-trim(123.5): 38 B-trim: 845 in 1/55
Lambda= 0.073603
statistics sampled from 43493 (43535) to 43493 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.802), E-opt: 0.2 (0.51), width: 16
Scan time: 11.550
The best scores are: opt bits E(85289)
NP_055544 (OMIM: 606863) thymocyte selection-assoc ( 526) 3660 402.0 2.3e-111
XP_016869574 (OMIM: 606863) PREDICTED: thymocyte s ( 504) 3246 358.0 3.9e-98
XP_005255949 (OMIM: 611416) PREDICTED: TOX high mo ( 575) 1327 154.3 9.4e-37
NP_001073899 (OMIM: 611416) TOX high mobility grou ( 576) 1320 153.5 1.6e-36
NP_001139660 (OMIM: 611416) TOX high mobility grou ( 571) 1259 147.0 1.4e-34
XP_016878631 (OMIM: 611416) PREDICTED: TOX high mo ( 572) 1252 146.3 2.3e-34
XP_011521304 (OMIM: 611416) PREDICTED: TOX high mo ( 553) 1248 145.9 3.1e-34
NP_055643 (OMIM: 614032) TOX high mobility group b ( 621) 926 111.7 6.6e-24
NP_001092267 (OMIM: 611163) TOX high mobility grou ( 506) 906 109.5 2.4e-23
NP_001092266 (OMIM: 611163) TOX high mobility grou ( 464) 885 107.3 1.1e-22
NP_116272 (OMIM: 611163) TOX high mobility group b ( 464) 885 107.3 1.1e-22
XP_006723947 (OMIM: 611163) PREDICTED: TOX high mo ( 515) 885 107.3 1.2e-22
NP_001290452 (OMIM: 614032) TOX high mobility grou ( 598) 881 106.9 1.8e-22
NP_001092268 (OMIM: 611163) TOX high mobility grou ( 488) 722 90.0 1.8e-17
XP_016883598 (OMIM: 611163) PREDICTED: TOX high mo ( 305) 660 83.3 1.2e-15
>>NP_055544 (OMIM: 606863) thymocyte selection-associate (526 aa)
initn: 3660 init1: 3660 opt: 3660 Z-score: 2120.2 bits: 402.0 E(85289): 2.3e-111
Smith-Waterman score: 3660; 100.0% identity (100.0% similar) in 526 aa overlap (1-526:1-526)
10 20 30 40 50 60
pF1KA0 MDVRFYPPPAQPAAAPDAPCLGPSPCLDPYYCNKFDGENMYMSMTEPSQDYVPASQSYPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MDVRFYPPPAQPAAAPDAPCLGPSPCLDPYYCNKFDGENMYMSMTEPSQDYVPASQSYPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 PSLESEDFNIPPITPPSLPDHSLVHLNEVESGYHSLCHPMNHNGLLPFHPQNMDLPEITV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PSLESEDFNIPPITPPSLPDHSLVHLNEVESGYHSLCHPMNHNGLLPFHPQNMDLPEITV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 SNMLGQDGTLLSNSISVMPDIRNPEGTQYSSHPQMAAMRPRGQPADIRQQPGMMPHGQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SNMLGQDGTLLSNSISVMPDIRNPEGTQYSSHPQMAAMRPRGQPADIRQQPGMMPHGQLT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 TINQSQLSAQLGLNMGGSNVPHNSPSPPGSKSATPSPSSSVHEDEGDDTSKINGGEKRPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TINQSQLSAQLGLNMGGSNVPHNSPSPPGSKSATPSPSSSVHEDEGDDTSKINGGEKRPA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 SDMGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SDMGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 GLGEEQKQVYKKKTEAAKKEYLKQLAAYRASLVSKSYSEPVDVKTSQPPQLINSKPSVFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GLGEEQKQVYKKKTEAAKKEYLKQLAAYRASLVSKSYSEPVDVKTSQPPQLINSKPSVFH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 GPSQAHSALYLSSHYHQQPGMNPHLTAMHPSLPRNIAPKPNNQMPVTVSIANMAVSPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GPSQAHSALYLSSHYHQQPGMNPHLTAMHPSLPRNIAPKPNNQMPVTVSIANMAVSPPPP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 LQISPPLHQHLNMQQHQPLTMQQPLGNQLPMQVQSALHSPTMQQGFTLQPDYQTIINPTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LQISPPLHQHLNMQQHQPLTMQQPLGNQLPMQVQSALHSPTMQQGFTLQPDYQTIINPTS
430 440 450 460 470 480
490 500 510 520
pF1KA0 TAAQVVTQAMEYVRSGCRNPPPQPVDWNNDYCSSGGMQRDKALYLT
::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TAAQVVTQAMEYVRSGCRNPPPQPVDWNNDYCSSGGMQRDKALYLT
490 500 510 520
>>XP_016869574 (OMIM: 606863) PREDICTED: thymocyte selec (504 aa)
initn: 3239 init1: 3239 opt: 3246 Z-score: 1882.9 bits: 358.0 E(85289): 3.9e-98
Smith-Waterman score: 3454; 95.8% identity (95.8% similar) in 526 aa overlap (1-526:1-504)
10 20 30 40 50 60
pF1KA0 MDVRFYPPPAQPAAAPDAPCLGPSPCLDPYYCNKFDGENMYMSMTEPSQDYVPASQSYPG
:::::::::::::::::::::::::::::::::: ::::
XP_016 MDVRFYPPPAQPAAAPDAPCLGPSPCLDPYYCNK----------------------SYPG
10 20 30
70 80 90 100 110 120
pF1KA0 PSLESEDFNIPPITPPSLPDHSLVHLNEVESGYHSLCHPMNHNGLLPFHPQNMDLPEITV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSLESEDFNIPPITPPSLPDHSLVHLNEVESGYHSLCHPMNHNGLLPFHPQNMDLPEITV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KA0 SNMLGQDGTLLSNSISVMPDIRNPEGTQYSSHPQMAAMRPRGQPADIRQQPGMMPHGQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNMLGQDGTLLSNSISVMPDIRNPEGTQYSSHPQMAAMRPRGQPADIRQQPGMMPHGQLT
100 110 120 130 140 150
190 200 210 220 230 240
pF1KA0 TINQSQLSAQLGLNMGGSNVPHNSPSPPGSKSATPSPSSSVHEDEGDDTSKINGGEKRPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TINQSQLSAQLGLNMGGSNVPHNSPSPPGSKSATPSPSSSVHEDEGDDTSKINGGEKRPA
160 170 180 190 200 210
250 260 270 280 290 300
pF1KA0 SDMGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDMGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWD
220 230 240 250 260 270
310 320 330 340 350 360
pF1KA0 GLGEEQKQVYKKKTEAAKKEYLKQLAAYRASLVSKSYSEPVDVKTSQPPQLINSKPSVFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLGEEQKQVYKKKTEAAKKEYLKQLAAYRASLVSKSYSEPVDVKTSQPPQLINSKPSVFH
280 290 300 310 320 330
370 380 390 400 410 420
pF1KA0 GPSQAHSALYLSSHYHQQPGMNPHLTAMHPSLPRNIAPKPNNQMPVTVSIANMAVSPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPSQAHSALYLSSHYHQQPGMNPHLTAMHPSLPRNIAPKPNNQMPVTVSIANMAVSPPPP
340 350 360 370 380 390
430 440 450 460 470 480
pF1KA0 LQISPPLHQHLNMQQHQPLTMQQPLGNQLPMQVQSALHSPTMQQGFTLQPDYQTIINPTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQISPPLHQHLNMQQHQPLTMQQPLGNQLPMQVQSALHSPTMQQGFTLQPDYQTIINPTS
400 410 420 430 440 450
490 500 510 520
pF1KA0 TAAQVVTQAMEYVRSGCRNPPPQPVDWNNDYCSSGGMQRDKALYLT
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAAQVVTQAMEYVRSGCRNPPPQPVDWNNDYCSSGGMQRDKALYLT
460 470 480 490 500
>>XP_005255949 (OMIM: 611416) PREDICTED: TOX high mobili (575 aa)
initn: 970 init1: 641 opt: 1327 Z-score: 780.8 bits: 154.3 E(85289): 9.4e-37
Smith-Waterman score: 1335; 49.1% identity (69.8% similar) in 493 aa overlap (1-464:1-475)
10 20 30 40 50 60
pF1KA0 MDVRFYPPPAQPAAAPDAPCLGPSPCLDPYYCNKFDGENMYMSMTEPSQDYVPASQSYPG
::::::: ::: : : . :: : .:: ..: ::.:.: .. . ::...
XP_005 MDVRFYP-----AAAGDPASLDFAQCLGYYGYSKFGNNNNYMNMAEANNAFFAASETFHT
10 20 30 40 50
70 80 90 100 110
pF1KA0 PSLESEDFNIPPITPPSLPDHSLVHLNEVESGYHSLCHPMNHNG--LLP-FHPQNMDLPE
::: .:.:.::::::: : .: . .: ...: :. .: . : : ::..:::
XP_005 PSLGDEEFEIPPITPPPESDPAL-GMPDVLLPFQALSDPLPSQGSEFTPQFPPQSLDLPS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KA0 ITVS-NMLGQDGTLLSNSISVMPDIRNPEGTQYSSHPQMAAMRPRGQPADIRQQPGMMPH
::.: :.. :::.: :... . : . . .:: . :.. :: . .: .. :.::
XP_005 ITISRNLVEQDGVLHSSGLHM--DQSHTQVSQYRQDPSLI-MRSIVHMTDAARS-GVMPP
120 130 140 150 160 170
180 190 200 210 220 230
pF1KA0 GQLTTINQSQLSAQLGLNMGGSNVPHNSPSPPGSKSATPSPSSSVHEDEGDDTSKINGGE
.:::::::::::::::::.::...::.:::::.:::::::::::..:...:.... : :
XP_005 AQLTTINQSQLSAQLGLNLGGASMPHTSPSPPASKSATPSPSSSINEEDADEANRAIG-E
180 190 200 210 220
240 250 260 270 280 290
pF1KA0 KRPASDMGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVA
:: : : :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KRAAPDSGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVA
230 240 250 260 270 280
300 310 320 330 340 350
pF1KA0 SMWDGLGEEQKQVYKKKTEAAKKEYLKQLAAYRASLVSKSYSEPVDVKTSQPPQLINSKP
::::.::::::::::.::::::::::: :::::::::::. .: ....: . : ..
XP_005 SMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYRASLVSKAAAESAEAQTIRSVQQTLAST
290 300 310 320 330 340
360 370 380 390 400 410
pF1KA0 SVFHGPSQAHSALYLSSHYHQQPGMNPHLTAMHPSLPRNIAPKP------NNQMPVTVSI
.. :.: :.. :. .. ... ::::.::::: ::. ..:.:
XP_005 NLT-------SSLLLNTPLSQHGTVSASPQTLQQSLPRSIAPKPLTMRLPMNQIVTSVTI
350 360 370 380 390 400
420 430 440 450
pF1KA0 A-NMA--VSPP-------------PPLQISPPLH--QH-LNMQQHQPLTMQQPLGNQLPM
: :: .. : : :.:: .. :: ...::.: .:: : .
XP_005 AANMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQ
410 420 430 440 450 460
460 470 480 490 500 510
pF1KA0 QVQSALHSPTMQQGFTLQPDYQTIINPTSTAAQVVTQAMEYVRSGCRNPPPQPVDWNNDY
: .:. .::
XP_005 LQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQ
470 480 490 500 510 520
>>NP_001073899 (OMIM: 611416) TOX high mobility group bo (576 aa)
initn: 924 init1: 641 opt: 1320 Z-score: 776.8 bits: 153.5 E(85289): 1.6e-36
Smith-Waterman score: 1328; 49.2% identity (69.6% similar) in 494 aa overlap (1-464:1-476)
10 20 30 40 50
pF1KA0 MDVRFYPPPAQPAAAPDAPCLGPSPCLDPYYCNKFDGENMYMSMTEPSQDYVPAS-QSYP
::::::: ::: : : . :: : .:: ..: ::.:.: .. . :: :..
NP_001 MDVRFYP-----AAAGDPASLDFAQCLGYYGYSKFGNNNNYMNMAEANNAFFAASEQTFH
10 20 30 40 50
60 70 80 90 100 110
pF1KA0 GPSLESEDFNIPPITPPSLPDHSLVHLNEVESGYHSLCHPMNHNG--LLP-FHPQNMDLP
::: .:.:.::::::: : .: . .: ...: :. .: . : : ::..:::
NP_001 TPSLGDEEFEIPPITPPPESDPAL-GMPDVLLPFQALSDPLPSQGSEFTPQFPPQSLDLP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KA0 EITVS-NMLGQDGTLLSNSISVMPDIRNPEGTQYSSHPQMAAMRPRGQPADIRQQPGMMP
::.: :.. :::.: :... . : . . .:: . :.. :: . .: .. :.::
NP_001 SITISRNLVEQDGVLHSSGLHM--DQSHTQVSQYRQDPSLI-MRSIVHMTDAARS-GVMP
120 130 140 150 160 170
180 190 200 210 220 230
pF1KA0 HGQLTTINQSQLSAQLGLNMGGSNVPHNSPSPPGSKSATPSPSSSVHEDEGDDTSKINGG
.:::::::::::::::::.::...::.:::::.:::::::::::..:...:.... :
NP_001 PAQLTTINQSQLSAQLGLNLGGASMPHTSPSPPASKSATPSPSSSINEEDADEANRAIG-
180 190 200 210 220
240 250 260 270 280 290
pF1KA0 EKRPASDMGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIV
::: : : ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKRAAPDSGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIV
230 240 250 260 270 280
300 310 320 330 340 350
pF1KA0 ASMWDGLGEEQKQVYKKKTEAAKKEYLKQLAAYRASLVSKSYSEPVDVKTSQPPQLINSK
:::::.::::::::::.::::::::::: :::::::::::. .: ....: . : ..
NP_001 ASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYRASLVSKAAAESAEAQTIRSVQQTLAS
290 300 310 320 330 340
360 370 380 390 400
pF1KA0 PSVFHGPSQAHSALYLSSHYHQQPGMNPHLTAMHPSLPRNIAPKP------NNQMPVTVS
.. :.: :.. :. .. ... ::::.::::: ::. ..:.
NP_001 TNLT-------SSLLLNTPLSQHGTVSASPQTLQQSLPRSIAPKPLTMRLPMNQIVTSVT
350 360 370 380 390 400
410 420 430 440 450
pF1KA0 IA-NMA--VSPP-------------PPLQISPPLH--QH-LNMQQHQPLTMQQPLGNQLP
:: :: .. : : :.:: .. :: ...::.: .:: :
NP_001 IAANMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQ
410 420 430 440 450 460
460 470 480 490 500 510
pF1KA0 MQVQSALHSPTMQQGFTLQPDYQTIINPTSTAAQVVTQAMEYVRSGCRNPPPQPVDWNND
. : .:. .::
NP_001 QLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHM
470 480 490 500 510 520
>>NP_001139660 (OMIM: 611416) TOX high mobility group bo (571 aa)
initn: 925 init1: 641 opt: 1259 Z-score: 741.8 bits: 147.0 E(85289): 1.4e-34
Smith-Waterman score: 1267; 49.3% identity (71.1% similar) in 460 aa overlap (34-464:25-471)
10 20 30 40 50 60
pF1KA0 RFYPPPAQPAAAPDAPCLGPSPCLDPYYCNKFDGENMYMSMTEPSQDYVPASQSYPGPSL
:: ..: ::.:.: .. . ::... :::
NP_001 MKCQPRSGARRIEERLHYLITTYLKFGNNNNYMNMAEANNAFFAASETFHTPSL
10 20 30 40 50
70 80 90 100 110 120
pF1KA0 ESEDFNIPPITPPSLPDHSLVHLNEVESGYHSLCHPMNHNG--LLP-FHPQNMDLPEITV
.:.:.::::::: : .: . .: ...: :. .: . : : ::..::: ::.
NP_001 GDEEFEIPPITPPPESDPAL-GMPDVLLPFQALSDPLPSQGSEFTPQFPPQSLDLPSITI
60 70 80 90 100 110
130 140 150 160 170
pF1KA0 S-NMLGQDGTLLSNSISVMPDIRNPEGTQYSSHPQMAAMRPRGQPADIRQQPGMMPHGQL
: :.. :::.: :... . : . . .:: . :.. :: . .: .. :.:: .::
NP_001 SRNLVEQDGVLHSSGLHM--DQSHTQVSQYRQDPSLI-MRSIVHMTDAARS-GVMPPAQL
120 130 140 150 160
180 190 200 210 220 230
pF1KA0 TTINQSQLSAQLGLNMGGSNVPHNSPSPPGSKSATPSPSSSVHEDEGDDTSKINGGEKRP
:::::::::::::::.::...::.:::::.:::::::::::..:...:.... : :::
NP_001 TTINQSQLSAQLGLNLGGASMPHTSPSPPASKSATPSPSSSINEEDADEANRAIG-EKRA
170 180 190 200 210 220
240 250 260 270 280 290
pF1KA0 ASDMGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMW
: : ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APDSGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMW
230 240 250 260 270 280
300 310 320 330 340 350
pF1KA0 DGLGEEQKQVYKKKTEAAKKEYLKQLAAYRASLVSKSYSEPVDVKTSQPPQLINSKPSVF
:.::::::::::.::::::::::: :::::::::::. .: ....: . : .. ..
NP_001 DSLGEEQKQVYKRKTEAAKKEYLKALAAYRASLVSKAAAESAEAQTIRSVQQTLASTNLT
290 300 310 320 330 340
360 370 380 390 400 410
pF1KA0 HGPSQAHSALYLSSHYHQQPGMNPHLTAMHPSLPRNIAPKP------NNQMPVTVSIA-N
:.: :.. :. .. ... ::::.::::: ::. ..:.:: :
NP_001 -------SSLLLNTPLSQHGTVSASPQTLQQSLPRSIAPKPLTMRLPMNQIVTSVTIAAN
350 360 370 380 390 400
420 430 440 450
pF1KA0 MA--VSPP-------------PPLQISPPLH--QH-LNMQQHQPLTMQQPLGNQLPMQVQ
: .. : : :.:: .. :: ...::.: .:: : . :
NP_001 MPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQ
410 420 430 440 450 460
460 470 480 490 500 510
pF1KA0 SALHSPTMQQGFTLQPDYQTIINPTSTAAQVVTQAMEYVRSGCRNPPPQPVDWNNDYCSS
.:. .::
NP_001 HQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQHQS
470 480 490 500 510 520
>>XP_016878631 (OMIM: 611416) PREDICTED: TOX high mobili (572 aa)
initn: 876 init1: 641 opt: 1252 Z-score: 737.8 bits: 146.3 E(85289): 2.3e-34
Smith-Waterman score: 1260; 49.5% identity (70.9% similar) in 461 aa overlap (34-464:25-472)
10 20 30 40 50 60
pF1KA0 RFYPPPAQPAAAPDAPCLGPSPCLDPYYCNKFDGENMYMSMTEPSQDYVPAS-QSYPGPS
:: ..: ::.:.: .. . :: :.. ::
XP_016 MKCQPRSGARRIEERLHYLITTYLKFGNNNNYMNMAEANNAFFAASEQTFHTPS
10 20 30 40 50
70 80 90 100 110
pF1KA0 LESEDFNIPPITPPSLPDHSLVHLNEVESGYHSLCHPMNHNG--LLP-FHPQNMDLPEIT
: .:.:.::::::: : .: . .: ...: :. .: . : : ::..::: ::
XP_016 LGDEEFEIPPITPPPESDPAL-GMPDVLLPFQALSDPLPSQGSEFTPQFPPQSLDLPSIT
60 70 80 90 100 110
120 130 140 150 160 170
pF1KA0 VS-NMLGQDGTLLSNSISVMPDIRNPEGTQYSSHPQMAAMRPRGQPADIRQQPGMMPHGQ
.: :.. :::.: :... . : . . .:: . :.. :: . .: .. :.:: .:
XP_016 ISRNLVEQDGVLHSSGLHM--DQSHTQVSQYRQDPSLI-MRSIVHMTDAARS-GVMPPAQ
120 130 140 150 160
180 190 200 210 220 230
pF1KA0 LTTINQSQLSAQLGLNMGGSNVPHNSPSPPGSKSATPSPSSSVHEDEGDDTSKINGGEKR
::::::::::::::::.::...::.:::::.:::::::::::..:...:.... : :::
XP_016 LTTINQSQLSAQLGLNLGGASMPHTSPSPPASKSATPSPSSSINEEDADEANRAIG-EKR
170 180 190 200 210 220
240 250 260 270 280 290
pF1KA0 PASDMGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASM
: : :::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAPDSGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASM
230 240 250 260 270 280
300 310 320 330 340 350
pF1KA0 WDGLGEEQKQVYKKKTEAAKKEYLKQLAAYRASLVSKSYSEPVDVKTSQPPQLINSKPSV
::.::::::::::.::::::::::: :::::::::::. .: ....: . : .. ..
XP_016 WDSLGEEQKQVYKRKTEAAKKEYLKALAAYRASLVSKAAAESAEAQTIRSVQQTLASTNL
290 300 310 320 330 340
360 370 380 390 400 410
pF1KA0 FHGPSQAHSALYLSSHYHQQPGMNPHLTAMHPSLPRNIAPKP------NNQMPVTVSIA-
:.: :.. :. .. ... ::::.::::: ::. ..:.::
XP_016 T-------SSLLLNTPLSQHGTVSASPQTLQQSLPRSIAPKPLTMRLPMNQIVTSVTIAA
350 360 370 380 390 400
420 430 440 450
pF1KA0 NMA--VSPP-------------PPLQISPPLH--QH-LNMQQHQPLTMQQPLGNQLPMQV
:: .. : : :.:: .. :: ...::.: .:: : .
XP_016 NMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQ
410 420 430 440 450 460
460 470 480 490 500 510
pF1KA0 QSALHSPTMQQGFTLQPDYQTIINPTSTAAQVVTQAMEYVRSGCRNPPPQPVDWNNDYCS
: .:. .::
XP_016 QHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQHQ
470 480 490 500 510 520
>>XP_011521304 (OMIM: 611416) PREDICTED: TOX high mobili (553 aa)
initn: 876 init1: 641 opt: 1248 Z-score: 735.7 bits: 145.9 E(85289): 3.1e-34
Smith-Waterman score: 1256; 49.0% identity (70.5% similar) in 465 aa overlap (30-464:4-453)
10 20 30 40 50
pF1KA0 MDVRFYPPPAQPAAAPDAPCLGPSPCLDPYYCNKFDGENMYMSMTEPSQDYVPAS-QSYP
. : : ..: ::.:.: .. . :: :..
XP_011 MAQFIC--FGNNNNYMNMAEANNAFFAASEQTFH
10 20 30
60 70 80 90 100 110
pF1KA0 GPSLESEDFNIPPITPPSLPDHSLVHLNEVESGYHSLCHPMNHNG--LLP-FHPQNMDLP
::: .:.:.::::::: : .: . .: ...: :. .: . : : ::..:::
XP_011 TPSLGDEEFEIPPITPPPESDPAL-GMPDVLLPFQALSDPLPSQGSEFTPQFPPQSLDLP
40 50 60 70 80 90
120 130 140 150 160 170
pF1KA0 EITVS-NMLGQDGTLLSNSISVMPDIRNPEGTQYSSHPQMAAMRPRGQPADIRQQPGMMP
::.: :.. :::.: :... . : . . .:: . :.. :: . .: .. :.::
XP_011 SITISRNLVEQDGVLHSSGLHM--DQSHTQVSQYRQDPSLI-MRSIVHMTDAARS-GVMP
100 110 120 130 140
180 190 200 210 220 230
pF1KA0 HGQLTTINQSQLSAQLGLNMGGSNVPHNSPSPPGSKSATPSPSSSVHEDEGDDTSKINGG
.:::::::::::::::::.::...::.:::::.:::::::::::..:...:.... :
XP_011 PAQLTTINQSQLSAQLGLNLGGASMPHTSPSPPASKSATPSPSSSINEEDADEANRAIG-
150 160 170 180 190 200
240 250 260 270 280 290
pF1KA0 EKRPASDMGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIV
::: : : ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKRAAPDSGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIV
210 220 230 240 250 260
300 310 320 330 340 350
pF1KA0 ASMWDGLGEEQKQVYKKKTEAAKKEYLKQLAAYRASLVSKSYSEPVDVKTSQPPQLINSK
:::::.::::::::::.::::::::::: :::::::::::. .: ....: . : ..
XP_011 ASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYRASLVSKAAAESAEAQTIRSVQQTLAS
270 280 290 300 310 320
360 370 380 390 400
pF1KA0 PSVFHGPSQAHSALYLSSHYHQQPGMNPHLTAMHPSLPRNIAPKP------NNQMPVTVS
.. :.: :.. :. .. ... ::::.::::: ::. ..:.
XP_011 TNLT-------SSLLLNTPLSQHGTVSASPQTLQQSLPRSIAPKPLTMRLPMNQIVTSVT
330 340 350 360 370
410 420 430 440 450
pF1KA0 IA-NMA--VSPP-------------PPLQISPPLH--QH-LNMQQHQPLTMQQPLGNQLP
:: :: .. : : :.:: .. :: ...::.: .:: :
XP_011 IAANMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQ
380 390 400 410 420 430
460 470 480 490 500 510
pF1KA0 MQVQSALHSPTMQQGFTLQPDYQTIINPTSTAAQVVTQAMEYVRSGCRNPPPQPVDWNND
. : .:. .::
XP_011 QLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHM
440 450 460 470 480 490
>>NP_055643 (OMIM: 614032) TOX high mobility group box f (621 aa)
initn: 1060 init1: 748 opt: 926 Z-score: 550.2 bits: 111.7 E(85289): 6.6e-24
Smith-Waterman score: 962; 38.8% identity (64.6% similar) in 492 aa overlap (37-508:6-483)
10 20 30 40 50 60
pF1KA0 PPPAQPAAAPDAPCLGPSPCLDPYYCNKFDGENMYMSMTEPSQDYVPASQSYPGPSLESE
:.. :...: ::. .. ..... ::: .:
NP_055 MEFPGGNDNYLTITGPSHPFLSGAETFHTPSLGDE
10 20 30
70 80 90 100 110 120
pF1KA0 DFNIPPITPPSLPDHSLVHLNEVESGYHSLCHPMN-HNGLLP--FHPQNMDLPEITVSNM
.:.::::. : : ::. ...: . . .: : . ..: . . :..:.: . ..
NP_055 EFEIPPISLDS--DPSLA-VSDVVGHFDDLADPSSSQDGSFSAQYGVQTLDMPVGMTHGL
40 50 60 70 80 90
130 140 150 160 170 180
pF1KA0 LGQDGTLLSNSISVMPDIRNPEGTQYSSHPQMAAMRPRGQPADIRQQPGMMPHGQLTTIN
. : : :::..... :. . :::::..: .. : .:. . :.: :.:::::.
NP_055 MEQGGGLLSGGLTM--DLDHSIGTQYSANPPVTIDVPM---TDMTS--GLMGHSQLTTID
100 110 120 130 140
190 200 210 220 230 240
pF1KA0 QSQLSAQLGLNMGGSNVPHNSPSPPGSKSATPSPSSSVHEDEGDDTSKINGGEKRPASDM
::.::.::::..::... . :: :.::::.::.::: .: . ..: . .
NP_055 QSELSSQLGLSLGGGTILPPAQSPEDRLSTTPSPTSSLHEDGVEDFRRQLPSQKTVVVEA
150 160 170 180 190 200
250 260 270 280 290 300
pF1KA0 GKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLG
::: :.:::.:::::::::::::::::::::::::::::::::::::::::::::::.::
NP_055 GKKQKAPKKRKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLG
210 220 230 240 250 260
310 320 330 340 350
pF1KA0 EEQKQVYKKKTEAAKKEYLKQLAAYRASLVSKSYSEPVDV------KTSQPPQLI-----
::::::::.::::::::::: ::::. . .. : :.. .: .:: .
NP_055 EEQKQVYKRKTEAAKKEYLKALAAYKDNQECQATVETVELDPAPPSQTPSPPPMATVDPA
270 280 290 300 310 320
360 370 380 390 400
pF1KA0 NSKPSVFHGPSQAHSALY---LSSHYHQQPGMNPHLTAMHPSLPRNIAPKPNNQMPVTVS
. :. .. :. . : . :::. .: . . .. .:.. . : : .:.:
NP_055 SPAPASIEPPALSPSIVVNSTLSSYVANQASSG---AGGQPNITKLIITKQMLPSSITMS
330 340 350 360 370 380
410 420 430 440 450 460
pF1KA0 IANMAVSPPPPLQISPPLHQ-HLNMQQHQPLTMQQPLGNQLPMQVQSALHSPTMQ-QGFT
..:.. : . : :. . . :: . : . .. . . .: . .::
NP_055 QGGMVTVIPATVVTSRGLQLGQTSTATIQPSQQAQIVTRSVLQAAAAAAAAASMQLPPPR
390 400 410 420 430 440
470 480 490 500 510 520
pF1KA0 LQPD-YQTIINPTSTAAQVVTQAMEYVRSGCRNPPPQPVDWNNDYCSSGGMQRDKALYLT
::: : . .: : ::. . .. ..:::: : :
NP_055 LQPPPLQQMPQPP-TQQQVTILQQPPPLQAMQQPPPQKVRINLQQQPPPLQIKSVPLPTL
450 460 470 480 490 500
NP_055 KMQTTLVPPTVESSPERPMNNSPEAHTVEAPSPETICEMITDVVPEVESPSQMDVELVSG
510 520 530 540 550 560
>>NP_001092267 (OMIM: 611163) TOX high mobility group bo (506 aa)
initn: 1110 init1: 629 opt: 906 Z-score: 540.0 bits: 109.5 E(85289): 2.4e-23
Smith-Waterman score: 1389; 46.1% identity (69.5% similar) in 544 aa overlap (1-526:1-506)
10 20 30 40 50 60
pF1KA0 MDVRFYPPPAQPAAAPDAPCLGPSPCLDPYYCNKFDGENMYMSMTEPSQDYVPASQSYPG
::::.:: .: : : : . :: :. .::::.. :..:.. . . . .::.: :
NP_001 MDVRLYPSAPAVGARPGAEPAGLAH-LDYYHGGKFDGDSAYVGMSDGNPELLSTSQTYNG
10 20 30 40 50
70 80 90 100 110
pF1KA0 PSLESEDFNIPPITPPSLPDHSLVHLNEVESGYHSLCHPMNHNGLLP-FHPQNMDLPEIT
: ..::..:::::::.::. ::.::.. :..:::::: .. ::::: . : :::: :
NP_001 QSENNEDYEIPPITPPNLPEPSLLHLGDHEASYHSLCHGLTPNGLLPAYSYQAMDLPAIM
60 70 80 90 100 110
120 130 140 150 160 170
pF1KA0 VSNMLGQDGTLLSNSISVMPDIRNPEGTQYSSHPQMAAMRPRGQPADIRQQPGMMPHGQL
:::::.::. :::.. .: : : : ..::. :.:. . .:.:. ...
NP_001 VSNMLAQDSHLLSGQ---LPTI------QEMVHSEVAAY-DSGRPGPLLGRPAMLA-SHM
120 130 140 150 160
180 190 200 210 220 230
pF1KA0 TTINQSQLSAQLGLNMGGSNVPHNSPSPPGSKSATPSPSSSVHEDEGDDTSKINGGEKRP
....:::: .:.:. :.. :.:::::::::::::::::..:.:.. ::.: ::::
NP_001 SALSQSQLISQMGIR---SSIAHSSPSPPGSKSATPSPSSSTQEEESEVHFKISG-EKRP
170 180 190 200 210 220
240 250 260 270 280 290
pF1KA0 ASDMGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMW
..: ::: :.:::::::::::::::::::::::::::::::::::.::::.:::::::::
NP_001 SADPGKKAKNPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMW
230 240 250 260 270 280
300 310 320 330 340 350
pF1KA0 DGLGEEQKQVYKKKTEAAKKEYLKQLAAYRASLVSKSYSEPVDVKTSQ--PP-QLINSKP
:.:::::::.::.::::::::::: :::::::::::: . ..:..: :: ... :
NP_001 DSLGEEQKQAYKRKTEAAKKEYLKALAAYRASLVSKSSPDQGETKSTQANPPAKMLPPKQ
290 300 310 320 330 340
360 370 380 390 400 410
pF1KA0 SVFHGPSQAHSALYLSSHYHQQPGMNPHLTAMHPSLPRNIAPKPNNQMPVTVSIANMAVS
.. :. : : : :. . : .: :: :... : . .: ....:
NP_001 PMYAMPGLA-SFLTPSDLQAFRSGASP------ASLARTLGSK--SLLP------GLSAS
350 360 370 380
420 430 440 450 460 470
pF1KA0 PPPP--LQISPPLHQHLNMQQHQPLTMQQPLGNQLPMQVQSALHSPTMQQGFTLQPDYQT
:::: . .:: :::.:.. : .. .: :.... : . :.. ..:: :
NP_001 PPPPPSFPLSPTLHQQLSLPPHAQGALLSP-----PVSMSPAPQPPVLPTPMALQ--VQL
390 400 410 420 430 440
480 490 500 510 520
pF1KA0 IINPTSTAAQVVTQAMEYVRSG--CRNPPPQPV---DWNNDY----C---SSGGMQRDKA
..:. . : . :. :. : : .:. ::...: : . . . :::.
NP_001 AMSPSPPGPQDFPHISEFPSSSGSCSPGPSNPTSSGDWDSSYPSGECGISTCSLLPRDKS
450 460 470 480 490 500
pF1KA0 LYLT
::::
NP_001 LYLT
>>NP_001092266 (OMIM: 611163) TOX high mobility group bo (464 aa)
initn: 1052 init1: 629 opt: 885 Z-score: 528.5 bits: 107.3 E(85289): 1.1e-22
Smith-Waterman score: 1291; 46.5% identity (70.1% similar) in 501 aa overlap (44-526:1-464)
20 30 40 50 60 70
pF1KA0 AAPDAPCLGPSPCLDPYYCNKFDGENMYMSMTEPSQDYVPASQSYPGPSLESEDFNIPPI
:.. . . . .::.: : : ..::..::::
NP_001 MSDGNPELLSTSQTYNGQSENNEDYEIPPI
10 20 30
80 90 100 110 120 130
pF1KA0 TPPSLPDHSLVHLNEVESGYHSLCHPMNHNGLLP-FHPQNMDLPEITVSNMLGQDGTLLS
:::.::. ::.::.. :..:::::: .. ::::: . : :::: : :::::.::. :::
NP_001 TPPNLPEPSLLHLGDHEASYHSLCHGLTPNGLLPAYSYQAMDLPAIMVSNMLAQDSHLLS
40 50 60 70 80 90
140 150 160 170 180 190
pF1KA0 NSISVMPDIRNPEGTQYSSHPQMAAMRPRGQPADIRQQPGMMPHGQLTTINQSQLSAQLG
.. .: : : : ..::. :.:. . .:.:. .......:::: .:.:
NP_001 GQ---LPTI------QEMVHSEVAAY-DSGRPGPLLGRPAMLA-SHMSALSQSQLISQMG
100 110 120 130
200 210 220 230 240 250
pF1KA0 LNMGGSNVPHNSPSPPGSKSATPSPSSSVHEDEGDDTSKINGGEKRPASDMGKKPKTPKK
. :.. :.:::::::::::::::::..:.:.. ::.: ::::..: ::: :.:::
NP_001 IR---SSIAHSSPSPPGSKSATPSPSSSTQEEESEVHFKISG-EKRPSADPGKKAKNPKK
140 150 160 170 180 190
260 270 280 290 300 310
pF1KA0 KKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQKQVYKK
::::::::::::::::::::::::::::::::.::::.::::::::::.:::::::.::.
NP_001 KKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQAYKR
200 210 220 230 240 250
320 330 340 350 360
pF1KA0 KTEAAKKEYLKQLAAYRASLVSKSYSEPVDVKTSQ--PP-QLINSKPSVFHGPSQAHSAL
::::::::::: :::::::::::: . ..:..: :: ... : .. :. : : :
NP_001 KTEAAKKEYLKALAAYRASLVSKSSPDQGETKSTQANPPAKMLPPKQPMYAMPGLA-SFL
260 270 280 290 300 310
370 380 390 400 410 420
pF1KA0 YLSSHYHQQPGMNPHLTAMHPSLPRNIAPKPNNQMPVTVSIANMAVSPPPP--LQISPPL
:. . : .: :: :... : . .: ....::::: . .:: :
NP_001 TPSDLQAFRSGASP------ASLARTLGSK--SLLP------GLSASPPPPPSFPLSPTL
320 330 340 350 360
430 440 450 460 470 480
pF1KA0 HQHLNMQQHQPLTMQQPLGNQLPMQVQSALHSPTMQQGFTLQPDYQTIINPTSTAAQVVT
::.:.. : .. .: :.... : . :.. ..:: : ..:. . :
NP_001 HQQLSLPPHAQGALLSP-----PVSMSPAPQPPVLPTPMALQ--VQLAMSPSPPGPQDFP
370 380 390 400 410
490 500 510 520
pF1KA0 QAMEYVRSG--CRNPPPQPV---DWNNDY----C---SSGGMQRDKALYLT
. :. :. : : .:. ::...: : . . . :::.::::
NP_001 HISEFPSSSGSCSPGPSNPTSSGDWDSSYPSGECGISTCSLLPRDKSLYLT
420 430 440 450 460
526 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 19:45:51 2016 done: Wed Nov 2 19:45:53 2016
Total Scan time: 11.550 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]