Result of FASTA (ccds) for
pF1KA0720
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0720, 1062 aa
1>>>pF1KA0720 1062 - 1062 aa - 1062 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.7063+/-0.00097; mu= -1.3764+/- 0.059
mean_var=296.1916+/-60.710, 0's: 0 Z-trim(115.3): 51 B-trim: 280 in 1/51
Lambda= 0.074523
statistics sampled from 15834 (15883) to 15834 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.785), E-opt: 0.2 (0.488), width: 16
Scan time: 6.020
The best scores are: opt bits E(32554)
CCDS41241.1 PLEKHG5 gene_id:57449|Hs108|chr1 (1062) 7155 783.4 0
CCDS41240.1 PLEKHG5 gene_id:57449|Hs108|chr1 (1083) 7148 782.6 0
CCDS57969.1 PLEKHG5 gene_id:57449|Hs108|chr1 (1085) 7140 781.8 0
CCDS57968.1 PLEKHG5 gene_id:57449|Hs108|chr1 (1075) 6969 763.4 0
CCDS79.1 PLEKHG5 gene_id:57449|Hs108|chr1 (1006) 6734 738.1 2.3e-212
CCDS57967.1 PLEKHG5 gene_id:57449|Hs108|chr1 ( 930) 6091 668.9 1.4e-191
CCDS44808.1 PLEKHG6 gene_id:55200|Hs108|chr12 ( 758) 1391 163.6 1.5e-39
CCDS8541.1 PLEKHG6 gene_id:55200|Hs108|chr12 ( 790) 1391 163.6 1.6e-39
>>CCDS41241.1 PLEKHG5 gene_id:57449|Hs108|chr1 (1062 aa)
initn: 7155 init1: 7155 opt: 7155 Z-score: 4170.5 bits: 783.4 E(32554): 0
Smith-Waterman score: 7155; 99.9% identity (100.0% similar) in 1062 aa overlap (1-1062:1-1062)
10 20 30 40 50 60
pF1KA0 MDDQSPAEKKGLRCQNPACMDKGRAAKVCHHADCQQLHRRGPLNLCEACDSKFHSTMHYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 MDDQSPAEKKGLRCQNPACMDKGRAAKVCHHADCQQLHRRGPLNLCEACDSKFHSTMHYD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 GHVRFDLPPQGSVLARNVSTRSCPPRTSPAVDLEEEEEESSVDGKGDRKSTGLKLSKKKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 GHVRFDLPPQGSVLARNVSTRSCPPRTSPAVDLEEEEEESSVDGKGDRKSTGLKLSKKKA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 RRRHTDDPSKECFTLKFDLNVDIETEIVPAMKKKSLGEVLLPVFERKGIALGKVDIYLDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 RRRHTDDPSKECFTLKFDLNVDIETEIVPAMKKKSLGEVLLPVFERKGIALGKVDIYLDQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 SNTPLSLTFEAYRFGGHYLRVKAPAKPGDEGKVEQGMKDSKSLSLPILRPAGTGPPALER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 SNTPLSLTFEAYRFGGHYLRVKAPAKPGDEGKVEQGMKDSKSLSLPILRPAGTGPPALER
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 VDAQSRRESLDILAPGRRRKNMSEFLGEASIPGQEPPTPSSCSLPSGSSGSTNSGDSWKN
:::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::
CCDS41 VDAQSRRESLDILAPGRRRKNMSEFLGEASIPGQEPPTPSSCSLPSGSSGSTNTGDSWKN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 RAASRFSGFFSSGPSTSAFGREVDKMEQLEGKLHTYSLFGLPRLPRGLRFDHDSWEEEYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 RAASRFSGFFSSGPSTSAFGREVDKMEQLEGKLHTYSLFGLPRLPRGLRFDHDSWEEEYD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 EDEDEDNACLRLEDSWRELIDGHEKLTRRQCHQQEAVWELLHTEASYIRKLRVIINLFLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 EDEDEDNACLRLEDSWRELIDGHEKLTRRQCHQQEAVWELLHTEASYIRKLRVIINLFLC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 CLLNLQESGLLCEVEAERLFSNIPEIAQLHRRLWASVMAPVLEKARRTRALLQPGDFLKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 CLLNLQESGLLCEVEAERLFSNIPEIAQLHRRLWASVMAPVLEKARRTRALLQPGDFLKG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 FKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRAYITWAEKHPQCQRLKLSDMLAKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 FKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRAYITWAEKHPQCQRLKLSDMLAKP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 HQRLTKYPLLLKSVLRKTEEPRAKEAVVAMIGSVERFIHHVNACMRQRQERQRLAAVVSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 HQRLTKYPLLLKSVLRKTEEPRAKEAVVAMIGSVERFIHHVNACMRQRQERQRLAAVVSR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 IDAYEVVESSSDEVDKLLKEFLHLDLTAPIPGASPEETRQLLLEGSLRMKEGKDSKMDVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 IDAYEVVESSSDEVDKLLKEFLHLDLTAPIPGASPEETRQLLLEGSLRMKEGKDSKMDVY
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 CFLFTDLLLVTKAVKKAERTRVIRPPLLVDKIVCRELRDPGSFLLIYLNEFHSAVGAYTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 CFLFTDLLLVTKAVKKAERTRVIRPPLLVDKIVCRELRDPGSFLLIYLNEFHSAVGAYTF
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 QASGQALCRGWVDTIYNAQNQLQQLRAQEPPGSQQPLQSLEEEEDEQEEEEEEEEEEEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 QASGQALCRGWVDTIYNAQNQLQQLRAQEPPGSQQPLQSLEEEEDEQEEEEEEEEEEEEG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 EDSGTSAASSPTIMRKSSGSPDSQHCASDGSTETLAMVVVEPGDTLSSPEFDSGPFSSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 EDSGTSAASSPTIMRKSSGSPDSQHCASDGSTETLAMVVVEPGDTLSSPEFDSGPFSSQS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 DETSLSTTASSATPTSELLPLGPVDGRSCSMDSAYGTLSPTSLQDFVAPGPMAELVPRAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 DETSLSTTASSATPTSELLPLGPVDGRSCSMDSAYGTLSPTSLQDFVAPGPMAELVPRAP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 ESPRVPSPPPSPRLRRRTPVQLLSCPPHLLKSKSEASLLQLLAGAGTHGTPSAPSRSLSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 ESPRVPSPPPSPRLRRRTPVQLLSCPPHLLKSKSEASLLQLLAGAGTHGTPSAPSRSLSE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LCLAVPAPGIRTQGSPQEAGPSWDCRGAPSPGSGPGLVGCLAGEPAGSHRKRCGDLPSGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 LCLAVPAPGIRTQGSPQEAGPSWDCRGAPSPGSGPGLVGCLAGEPAGSHRKRCGDLPSGA
970 980 990 1000 1010 1020
1030 1040 1050 1060
pF1KA0 SPRVQPEPPPGVSAQHRKLTLAQLYRIRTTLLLNSTLTASEV
::::::::::::::::::::::::::::::::::::::::::
CCDS41 SPRVQPEPPPGVSAQHRKLTLAQLYRIRTTLLLNSTLTASEV
1030 1040 1050 1060
>>CCDS41240.1 PLEKHG5 gene_id:57449|Hs108|chr1 (1083 aa)
initn: 7148 init1: 7148 opt: 7148 Z-score: 4166.3 bits: 782.6 E(32554): 0
Smith-Waterman score: 7148; 99.9% identity (100.0% similar) in 1061 aa overlap (2-1062:23-1083)
10 20 30
pF1KA0 MDDQSPAEKKGLRCQNPACMDKGRAAKVCHHADCQQLHR
::::::::::::::::::::::::::::::::::::::
CCDS41 MNSVLTKHGSPPRSWLSLCSGTDDQSPAEKKGLRCQNPACMDKGRAAKVCHHADCQQLHR
10 20 30 40 50 60
40 50 60 70 80 90
pF1KA0 RGPLNLCEACDSKFHSTMHYDGHVRFDLPPQGSVLARNVSTRSCPPRTSPAVDLEEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 RGPLNLCEACDSKFHSTMHYDGHVRFDLPPQGSVLARNVSTRSCPPRTSPAVDLEEEEEE
70 80 90 100 110 120
100 110 120 130 140 150
pF1KA0 SSVDGKGDRKSTGLKLSKKKARRRHTDDPSKECFTLKFDLNVDIETEIVPAMKKKSLGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 SSVDGKGDRKSTGLKLSKKKARRRHTDDPSKECFTLKFDLNVDIETEIVPAMKKKSLGEV
130 140 150 160 170 180
160 170 180 190 200 210
pF1KA0 LLPVFERKGIALGKVDIYLDQSNTPLSLTFEAYRFGGHYLRVKAPAKPGDEGKVEQGMKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 LLPVFERKGIALGKVDIYLDQSNTPLSLTFEAYRFGGHYLRVKAPAKPGDEGKVEQGMKD
190 200 210 220 230 240
220 230 240 250 260 270
pF1KA0 SKSLSLPILRPAGTGPPALERVDAQSRRESLDILAPGRRRKNMSEFLGEASIPGQEPPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 SKSLSLPILRPAGTGPPALERVDAQSRRESLDILAPGRRRKNMSEFLGEASIPGQEPPTP
250 260 270 280 290 300
280 290 300 310 320 330
pF1KA0 SSCSLPSGSSGSTNSGDSWKNRAASRFSGFFSSGPSTSAFGREVDKMEQLEGKLHTYSLF
::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::
CCDS41 SSCSLPSGSSGSTNTGDSWKNRAASRFSGFFSSGPSTSAFGREVDKMEQLEGKLHTYSLF
310 320 330 340 350 360
340 350 360 370 380 390
pF1KA0 GLPRLPRGLRFDHDSWEEEYDEDEDEDNACLRLEDSWRELIDGHEKLTRRQCHQQEAVWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 GLPRLPRGLRFDHDSWEEEYDEDEDEDNACLRLEDSWRELIDGHEKLTRRQCHQQEAVWE
370 380 390 400 410 420
400 410 420 430 440 450
pF1KA0 LLHTEASYIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNIPEIAQLHRRLWASVMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 LLHTEASYIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNIPEIAQLHRRLWASVMA
430 440 450 460 470 480
460 470 480 490 500 510
pF1KA0 PVLEKARRTRALLQPGDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRAYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 PVLEKARRTRALLQPGDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRAYI
490 500 510 520 530 540
520 530 540 550 560 570
pF1KA0 TWAEKHPQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTEEPRAKEAVVAMIGSVERFIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 TWAEKHPQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTEEPRAKEAVVAMIGSVERFIH
550 560 570 580 590 600
580 590 600 610 620 630
pF1KA0 HVNACMRQRQERQRLAAVVSRIDAYEVVESSSDEVDKLLKEFLHLDLTAPIPGASPEETR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 HVNACMRQRQERQRLAAVVSRIDAYEVVESSSDEVDKLLKEFLHLDLTAPIPGASPEETR
610 620 630 640 650 660
640 650 660 670 680 690
pF1KA0 QLLLEGSLRMKEGKDSKMDVYCFLFTDLLLVTKAVKKAERTRVIRPPLLVDKIVCRELRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 QLLLEGSLRMKEGKDSKMDVYCFLFTDLLLVTKAVKKAERTRVIRPPLLVDKIVCRELRD
670 680 690 700 710 720
700 710 720 730 740 750
pF1KA0 PGSFLLIYLNEFHSAVGAYTFQASGQALCRGWVDTIYNAQNQLQQLRAQEPPGSQQPLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 PGSFLLIYLNEFHSAVGAYTFQASGQALCRGWVDTIYNAQNQLQQLRAQEPPGSQQPLQS
730 740 750 760 770 780
760 770 780 790 800 810
pF1KA0 LEEEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASDGSTETLAMVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 LEEEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASDGSTETLAMVV
790 800 810 820 830 840
820 830 840 850 860 870
pF1KA0 VEPGDTLSSPEFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVDGRSCSMDSAYGTLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 VEPGDTLSSPEFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVDGRSCSMDSAYGTLS
850 860 870 880 890 900
880 890 900 910 920 930
pF1KA0 PTSLQDFVAPGPMAELVPRAPESPRVPSPPPSPRLRRRTPVQLLSCPPHLLKSKSEASLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 PTSLQDFVAPGPMAELVPRAPESPRVPSPPPSPRLRRRTPVQLLSCPPHLLKSKSEASLL
910 920 930 940 950 960
940 950 960 970 980 990
pF1KA0 QLLAGAGTHGTPSAPSRSLSELCLAVPAPGIRTQGSPQEAGPSWDCRGAPSPGSGPGLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 QLLAGAGTHGTPSAPSRSLSELCLAVPAPGIRTQGSPQEAGPSWDCRGAPSPGSGPGLVG
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KA0 CLAGEPAGSHRKRCGDLPSGASPRVQPEPPPGVSAQHRKLTLAQLYRIRTTLLLNSTLTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 CLAGEPAGSHRKRCGDLPSGASPRVQPEPPPGVSAQHRKLTLAQLYRIRTTLLLNSTLTA
1030 1040 1050 1060 1070 1080
1060
pF1KA0 SEV
:::
CCDS41 SEV
>>CCDS57969.1 PLEKHG5 gene_id:57449|Hs108|chr1 (1085 aa)
initn: 7140 init1: 7140 opt: 7140 Z-score: 4161.6 bits: 781.8 E(32554): 0
Smith-Waterman score: 7140; 99.9% identity (100.0% similar) in 1060 aa overlap (3-1062:26-1085)
10 20 30
pF1KA0 MDDQSPAEKKGLRCQNPACMDKGRAAKVCHHADCQQL
:::::::::::::::::::::::::::::::::::
CCDS57 MSLGERGSPQTFGGSSVSKGSDAGHDQSPAEKKGLRCQNPACMDKGRAAKVCHHADCQQL
10 20 30 40 50 60
40 50 60 70 80 90
pF1KA0 HRRGPLNLCEACDSKFHSTMHYDGHVRFDLPPQGSVLARNVSTRSCPPRTSPAVDLEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 HRRGPLNLCEACDSKFHSTMHYDGHVRFDLPPQGSVLARNVSTRSCPPRTSPAVDLEEEE
70 80 90 100 110 120
100 110 120 130 140 150
pF1KA0 EESSVDGKGDRKSTGLKLSKKKARRRHTDDPSKECFTLKFDLNVDIETEIVPAMKKKSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 EESSVDGKGDRKSTGLKLSKKKARRRHTDDPSKECFTLKFDLNVDIETEIVPAMKKKSLG
130 140 150 160 170 180
160 170 180 190 200 210
pF1KA0 EVLLPVFERKGIALGKVDIYLDQSNTPLSLTFEAYRFGGHYLRVKAPAKPGDEGKVEQGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 EVLLPVFERKGIALGKVDIYLDQSNTPLSLTFEAYRFGGHYLRVKAPAKPGDEGKVEQGM
190 200 210 220 230 240
220 230 240 250 260 270
pF1KA0 KDSKSLSLPILRPAGTGPPALERVDAQSRRESLDILAPGRRRKNMSEFLGEASIPGQEPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 KDSKSLSLPILRPAGTGPPALERVDAQSRRESLDILAPGRRRKNMSEFLGEASIPGQEPP
250 260 270 280 290 300
280 290 300 310 320 330
pF1KA0 TPSSCSLPSGSSGSTNSGDSWKNRAASRFSGFFSSGPSTSAFGREVDKMEQLEGKLHTYS
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
CCDS57 TPSSCSLPSGSSGSTNTGDSWKNRAASRFSGFFSSGPSTSAFGREVDKMEQLEGKLHTYS
310 320 330 340 350 360
340 350 360 370 380 390
pF1KA0 LFGLPRLPRGLRFDHDSWEEEYDEDEDEDNACLRLEDSWRELIDGHEKLTRRQCHQQEAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 LFGLPRLPRGLRFDHDSWEEEYDEDEDEDNACLRLEDSWRELIDGHEKLTRRQCHQQEAV
370 380 390 400 410 420
400 410 420 430 440 450
pF1KA0 WELLHTEASYIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNIPEIAQLHRRLWASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 WELLHTEASYIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNIPEIAQLHRRLWASV
430 440 450 460 470 480
460 470 480 490 500 510
pF1KA0 MAPVLEKARRTRALLQPGDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 MAPVLEKARRTRALLQPGDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRA
490 500 510 520 530 540
520 530 540 550 560 570
pF1KA0 YITWAEKHPQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTEEPRAKEAVVAMIGSVERF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 YITWAEKHPQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTEEPRAKEAVVAMIGSVERF
550 560 570 580 590 600
580 590 600 610 620 630
pF1KA0 IHHVNACMRQRQERQRLAAVVSRIDAYEVVESSSDEVDKLLKEFLHLDLTAPIPGASPEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 IHHVNACMRQRQERQRLAAVVSRIDAYEVVESSSDEVDKLLKEFLHLDLTAPIPGASPEE
610 620 630 640 650 660
640 650 660 670 680 690
pF1KA0 TRQLLLEGSLRMKEGKDSKMDVYCFLFTDLLLVTKAVKKAERTRVIRPPLLVDKIVCREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 TRQLLLEGSLRMKEGKDSKMDVYCFLFTDLLLVTKAVKKAERTRVIRPPLLVDKIVCREL
670 680 690 700 710 720
700 710 720 730 740 750
pF1KA0 RDPGSFLLIYLNEFHSAVGAYTFQASGQALCRGWVDTIYNAQNQLQQLRAQEPPGSQQPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 RDPGSFLLIYLNEFHSAVGAYTFQASGQALCRGWVDTIYNAQNQLQQLRAQEPPGSQQPL
730 740 750 760 770 780
760 770 780 790 800 810
pF1KA0 QSLEEEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASDGSTETLAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 QSLEEEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASDGSTETLAM
790 800 810 820 830 840
820 830 840 850 860 870
pF1KA0 VVVEPGDTLSSPEFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVDGRSCSMDSAYGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 VVVEPGDTLSSPEFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVDGRSCSMDSAYGT
850 860 870 880 890 900
880 890 900 910 920 930
pF1KA0 LSPTSLQDFVAPGPMAELVPRAPESPRVPSPPPSPRLRRRTPVQLLSCPPHLLKSKSEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 LSPTSLQDFVAPGPMAELVPRAPESPRVPSPPPSPRLRRRTPVQLLSCPPHLLKSKSEAS
910 920 930 940 950 960
940 950 960 970 980 990
pF1KA0 LLQLLAGAGTHGTPSAPSRSLSELCLAVPAPGIRTQGSPQEAGPSWDCRGAPSPGSGPGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 LLQLLAGAGTHGTPSAPSRSLSELCLAVPAPGIRTQGSPQEAGPSWDCRGAPSPGSGPGL
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KA0 VGCLAGEPAGSHRKRCGDLPSGASPRVQPEPPPGVSAQHRKLTLAQLYRIRTTLLLNSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 VGCLAGEPAGSHRKRCGDLPSGASPRVQPEPPPGVSAQHRKLTLAQLYRIRTTLLLNSTL
1030 1040 1050 1060 1070 1080
1060
pF1KA0 TASEV
:::::
CCDS57 TASEV
>>CCDS57968.1 PLEKHG5 gene_id:57449|Hs108|chr1 (1075 aa)
initn: 6963 init1: 6963 opt: 6969 Z-score: 4062.3 bits: 763.4 E(32554): 0
Smith-Waterman score: 6969; 98.1% identity (98.8% similar) in 1061 aa overlap (6-1062:16-1075)
10 20 30 40
pF1KA0 MDDQSPAEKKGLRCQNPACMDKGRA----AKVCHHADCQQLHRRGPLNLC
:. :: ..:. ::: ..:::::::::::::::::::
CCDS57 MGTGPGVSGRLAASRPGPGLPLRDSEPS-WAGGRARDGDSQVCHHADCQQLHRRGPLNLC
10 20 30 40 50
50 60 70 80 90 100
pF1KA0 EACDSKFHSTMHYDGHVRFDLPPQGSVLARNVSTRSCPPRTSPAVDLEEEEEESSVDGKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 EACDSKFHSTMHYDGHVRFDLPPQGSVLARNVSTRSCPPRTSPAVDLEEEEEESSVDGKG
60 70 80 90 100 110
110 120 130 140 150 160
pF1KA0 DRKSTGLKLSKKKARRRHTDDPSKECFTLKFDLNVDIETEIVPAMKKKSLGEVLLPVFER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 DRKSTGLKLSKKKARRRHTDDPSKECFTLKFDLNVDIETEIVPAMKKKSLGEVLLPVFER
120 130 140 150 160 170
170 180 190 200 210 220
pF1KA0 KGIALGKVDIYLDQSNTPLSLTFEAYRFGGHYLRVKAPAKPGDEGKVEQGMKDSKSLSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 KGIALGKVDIYLDQSNTPLSLTFEAYRFGGHYLRVKAPAKPGDEGKVEQGMKDSKSLSLP
180 190 200 210 220 230
230 240 250 260 270 280
pF1KA0 ILRPAGTGPPALERVDAQSRRESLDILAPGRRRKNMSEFLGEASIPGQEPPTPSSCSLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 ILRPAGTGPPALERVDAQSRRESLDILAPGRRRKNMSEFLGEASIPGQEPPTPSSCSLPS
240 250 260 270 280 290
290 300 310 320 330 340
pF1KA0 GSSGSTNSGDSWKNRAASRFSGFFSSGPSTSAFGREVDKMEQLEGKLHTYSLFGLPRLPR
:::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 GSSGSTNTGDSWKNRAASRFSGFFSSGPSTSAFGREVDKMEQLEGKLHTYSLFGLPRLPR
300 310 320 330 340 350
350 360 370 380 390 400
pF1KA0 GLRFDHDSWEEEYDEDEDEDNACLRLEDSWRELIDGHEKLTRRQCHQQEAVWELLHTEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 GLRFDHDSWEEEYDEDEDEDNACLRLEDSWRELIDGHEKLTRRQCHQQEAVWELLHTEAS
360 370 380 390 400 410
410 420 430 440 450 460
pF1KA0 YIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNIPEIAQLHRRLWASVMAPVLEKAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 YIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNIPEIAQLHRRLWASVMAPVLEKAR
420 430 440 450 460 470
470 480 490 500 510 520
pF1KA0 RTRALLQPGDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRAYITWAEKHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 RTRALLQPGDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRAYITWAEKHP
480 490 500 510 520 530
530 540 550 560 570 580
pF1KA0 QCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTEEPRAKEAVVAMIGSVERFIHHVNACMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 QCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTEEPRAKEAVVAMIGSVERFIHHVNACMR
540 550 560 570 580 590
590 600 610 620 630 640
pF1KA0 QRQERQRLAAVVSRIDAYEVVESSSDEVDKLLKEFLHLDLTAPIPGASPEETRQLLLEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 QRQERQRLAAVVSRIDAYEVVESSSDEVDKLLKEFLHLDLTAPIPGASPEETRQLLLEGS
600 610 620 630 640 650
650 660 670 680 690 700
pF1KA0 LRMKEGKDSKMDVYCFLFTDLLLVTKAVKKAERTRVIRPPLLVDKIVCRELRDPGSFLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 LRMKEGKDSKMDVYCFLFTDLLLVTKAVKKAERTRVIRPPLLVDKIVCRELRDPGSFLLI
660 670 680 690 700 710
710 720 730 740 750 760
pF1KA0 YLNEFHSAVGAYTFQASGQALCRGWVDTIYNAQNQLQQLRAQEPPGSQQPLQSLEEEEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 YLNEFHSAVGAYTFQASGQALCRGWVDTIYNAQNQLQQLRAQEPPGSQQPLQSLEEEEDE
720 730 740 750 760 770
770 780 790 800 810 820
pF1KA0 QEEEEEEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASDGSTETLAMVVVEPGDTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 QEEEEEEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASDGSTETLAMVVVEPGDTL
780 790 800 810 820 830
830 840 850 860 870 880
pF1KA0 SSPEFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVDGRSCSMDSAYGTLSPTSLQDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 SSPEFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVDGRSCSMDSAYGTLSPTSLQDF
840 850 860 870 880 890
890 900 910 920 930 940
pF1KA0 VAPGPMAELVPRAPESPRVPSPPPSPRLRRRTPVQLLSCPPHLLKSKSEASLLQLLAGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 VAPGPMAELVPRAPESPRVPSPPPSPRLRRRTPVQLLSCPPHLLKSKSEASLLQLLAGAG
900 910 920 930 940 950
950 960 970 980 990 1000
pF1KA0 THGTPSAPSRSLSELCLAVPAPGIRTQGSPQEAGPSWDCRGAPSPGSGPGLVGCLAGEPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 THGTPSAPSRSLSELCLAVPAPGIRTQGSPQEAGPSWDCRGAPSPGSGPGLVGCLAGEPA
960 970 980 990 1000 1010
1010 1020 1030 1040 1050 1060
pF1KA0 GSHRKRCGDLPSGASPRVQPEPPPGVSAQHRKLTLAQLYRIRTTLLLNSTLTASEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 GSHRKRCGDLPSGASPRVQPEPPPGVSAQHRKLTLAQLYRIRTTLLLNSTLTASEV
1020 1030 1040 1050 1060 1070
>>CCDS79.1 PLEKHG5 gene_id:57449|Hs108|chr1 (1006 aa)
initn: 6734 init1: 6734 opt: 6734 Z-score: 3926.2 bits: 738.1 E(32554): 2.3e-212
Smith-Waterman score: 6734; 99.9% identity (100.0% similar) in 1006 aa overlap (57-1062:1-1006)
30 40 50 60 70 80
pF1KA0 KVCHHADCQQLHRRGPLNLCEACDSKFHSTMHYDGHVRFDLPPQGSVLARNVSTRSCPPR
::::::::::::::::::::::::::::::
CCDS79 MHYDGHVRFDLPPQGSVLARNVSTRSCPPR
10 20 30
90 100 110 120 130 140
pF1KA0 TSPAVDLEEEEEESSVDGKGDRKSTGLKLSKKKARRRHTDDPSKECFTLKFDLNVDIETE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS79 TSPAVDLEEEEEESSVDGKGDRKSTGLKLSKKKARRRHTDDPSKECFTLKFDLNVDIETE
40 50 60 70 80 90
150 160 170 180 190 200
pF1KA0 IVPAMKKKSLGEVLLPVFERKGIALGKVDIYLDQSNTPLSLTFEAYRFGGHYLRVKAPAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS79 IVPAMKKKSLGEVLLPVFERKGIALGKVDIYLDQSNTPLSLTFEAYRFGGHYLRVKAPAK
100 110 120 130 140 150
210 220 230 240 250 260
pF1KA0 PGDEGKVEQGMKDSKSLSLPILRPAGTGPPALERVDAQSRRESLDILAPGRRRKNMSEFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS79 PGDEGKVEQGMKDSKSLSLPILRPAGTGPPALERVDAQSRRESLDILAPGRRRKNMSEFL
160 170 180 190 200 210
270 280 290 300 310 320
pF1KA0 GEASIPGQEPPTPSSCSLPSGSSGSTNSGDSWKNRAASRFSGFFSSGPSTSAFGREVDKM
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
CCDS79 GEASIPGQEPPTPSSCSLPSGSSGSTNTGDSWKNRAASRFSGFFSSGPSTSAFGREVDKM
220 230 240 250 260 270
330 340 350 360 370 380
pF1KA0 EQLEGKLHTYSLFGLPRLPRGLRFDHDSWEEEYDEDEDEDNACLRLEDSWRELIDGHEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS79 EQLEGKLHTYSLFGLPRLPRGLRFDHDSWEEEYDEDEDEDNACLRLEDSWRELIDGHEKL
280 290 300 310 320 330
390 400 410 420 430 440
pF1KA0 TRRQCHQQEAVWELLHTEASYIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNIPEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS79 TRRQCHQQEAVWELLHTEASYIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNIPEI
340 350 360 370 380 390
450 460 470 480 490 500
pF1KA0 AQLHRRLWASVMAPVLEKARRTRALLQPGDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS79 AQLHRRLWASVMAPVLEKARRTRALLQPGDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMR
400 410 420 430 440 450
510 520 530 540 550 560
pF1KA0 GLLRDNDLFRAYITWAEKHPQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTEEPRAKEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS79 GLLRDNDLFRAYITWAEKHPQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTEEPRAKEA
460 470 480 490 500 510
570 580 590 600 610 620
pF1KA0 VVAMIGSVERFIHHVNACMRQRQERQRLAAVVSRIDAYEVVESSSDEVDKLLKEFLHLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS79 VVAMIGSVERFIHHVNACMRQRQERQRLAAVVSRIDAYEVVESSSDEVDKLLKEFLHLDL
520 530 540 550 560 570
630 640 650 660 670 680
pF1KA0 TAPIPGASPEETRQLLLEGSLRMKEGKDSKMDVYCFLFTDLLLVTKAVKKAERTRVIRPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS79 TAPIPGASPEETRQLLLEGSLRMKEGKDSKMDVYCFLFTDLLLVTKAVKKAERTRVIRPP
580 590 600 610 620 630
690 700 710 720 730 740
pF1KA0 LLVDKIVCRELRDPGSFLLIYLNEFHSAVGAYTFQASGQALCRGWVDTIYNAQNQLQQLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS79 LLVDKIVCRELRDPGSFLLIYLNEFHSAVGAYTFQASGQALCRGWVDTIYNAQNQLQQLR
640 650 660 670 680 690
750 760 770 780 790 800
pF1KA0 AQEPPGSQQPLQSLEEEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS79 AQEPPGSQQPLQSLEEEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHC
700 710 720 730 740 750
810 820 830 840 850 860
pF1KA0 ASDGSTETLAMVVVEPGDTLSSPEFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS79 ASDGSTETLAMVVVEPGDTLSSPEFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVDG
760 770 780 790 800 810
870 880 890 900 910 920
pF1KA0 RSCSMDSAYGTLSPTSLQDFVAPGPMAELVPRAPESPRVPSPPPSPRLRRRTPVQLLSCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS79 RSCSMDSAYGTLSPTSLQDFVAPGPMAELVPRAPESPRVPSPPPSPRLRRRTPVQLLSCP
820 830 840 850 860 870
930 940 950 960 970 980
pF1KA0 PHLLKSKSEASLLQLLAGAGTHGTPSAPSRSLSELCLAVPAPGIRTQGSPQEAGPSWDCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS79 PHLLKSKSEASLLQLLAGAGTHGTPSAPSRSLSELCLAVPAPGIRTQGSPQEAGPSWDCR
880 890 900 910 920 930
990 1000 1010 1020 1030 1040
pF1KA0 GAPSPGSGPGLVGCLAGEPAGSHRKRCGDLPSGASPRVQPEPPPGVSAQHRKLTLAQLYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS79 GAPSPGSGPGLVGCLAGEPAGSHRKRCGDLPSGASPRVQPEPPPGVSAQHRKLTLAQLYR
940 950 960 970 980 990
1050 1060
pF1KA0 IRTTLLLNSTLTASEV
::::::::::::::::
CCDS79 IRTTLLLNSTLTASEV
1000
>>CCDS57967.1 PLEKHG5 gene_id:57449|Hs108|chr1 (930 aa)
initn: 6078 init1: 6078 opt: 6091 Z-score: 3553.1 bits: 668.9 E(32554): 1.4e-191
Smith-Waterman score: 6091; 98.6% identity (99.2% similar) in 928 aa overlap (57-984:1-926)
30 40 50 60 70 80
pF1KA0 KVCHHADCQQLHRRGPLNLCEACDSKFHSTMHYDGHVRFDLPPQGSVLARNVSTRSCPPR
::::::::::::::::::::::::::::::
CCDS57 MHYDGHVRFDLPPQGSVLARNVSTRSCPPR
10 20 30
90 100 110 120 130 140
pF1KA0 TSPAVDLEEEEEESSVDGKGDRKSTGLKLSKKKARRRHTDDPSKECFTLKFDLNVDIETE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 TSPAVDLEEEEEESSVDGKGDRKSTGLKLSKKKARRRHTDDPSKECFTLKFDLNVDIETE
40 50 60 70 80 90
150 160 170 180 190 200
pF1KA0 IVPAMKKKSLGEVLLPVFERKGIALGKVDIYLDQSNTPLSLTFEAYRFGGHYLRVKAPAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 IVPAMKKKSLGEVLLPVFERKGIALGKVDIYLDQSNTPLSLTFEAYRFGGHYLRVKAPAK
100 110 120 130 140 150
210 220 230 240 250 260
pF1KA0 PGDEGKVEQGMKDSKSLSLPILRPAGTGPPALERVDAQSRRESLDILAPGRRRKNMSEFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 PGDEGKVEQGMKDSKSLSLPILRPAGTGPPALERVDAQSRRESLDILAPGRRRKNMSEFL
160 170 180 190 200 210
270 280 290 300 310 320
pF1KA0 GEASIPGQEPPTPSSCSLPSGSSGSTNSGDSWKNRAASRFSGFFSSGPSTSAFGREVDKM
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
CCDS57 GEASIPGQEPPTPSSCSLPSGSSGSTNTGDSWKNRAASRFSGFFSSGPSTSAFGREVDKM
220 230 240 250 260 270
330 340 350 360 370 380
pF1KA0 EQLEGKLHTYSLFGLPRLPRGLRFDHDSWEEEYDEDEDEDNACLRLEDSWRELIDGHEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 EQLEGKLHTYSLFGLPRLPRGLRFDHDSWEEEYDEDEDEDNACLRLEDSWRELIDGHEKL
280 290 300 310 320 330
390 400 410 420 430 440
pF1KA0 TRRQCHQQEAVWELLHTEASYIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNIPEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 TRRQCHQQEAVWELLHTEASYIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNIPEI
340 350 360 370 380 390
450 460 470 480 490 500
pF1KA0 AQLHRRLWASVMAPVLEKARRTRALLQPGDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 AQLHRRLWASVMAPVLEKARRTRALLQPGDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMR
400 410 420 430 440 450
510 520 530 540 550 560
pF1KA0 GLLRDNDLFRAYITWAEKHPQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTEEPRAKEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 GLLRDNDLFRAYITWAEKHPQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTEEPRAKEA
460 470 480 490 500 510
570 580 590 600 610 620
pF1KA0 VVAMIGSVERFIHHVNACMRQRQERQRLAAVVSRIDAYEVVESSSDEVDKLLKEFLHLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 VVAMIGSVERFIHHVNACMRQRQERQRLAAVVSRIDAYEVVESSSDEVDKLLKEFLHLDL
520 530 540 550 560 570
630 640 650 660 670 680
pF1KA0 TAPIPGASPEETRQLLLEGSLRMKEGKDSKMDVYCFLFTDLLLVTKAVKKAERTRVIRPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 TAPIPGASPEETRQLLLEGSLRMKEGKDSKMDVYCFLFTDLLLVTKAVKKAERTRVIRPP
580 590 600 610 620 630
690 700 710 720 730 740
pF1KA0 LLVDKIVCRELRDPGSFLLIYLNEFHSAVGAYTFQASGQALCRGWVDTIYNAQNQLQQLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 LLVDKIVCRELRDPGSFLLIYLNEFHSAVGAYTFQASGQALCRGWVDTIYNAQNQLQQLR
640 650 660 670 680 690
750 760 770 780 790 800
pF1KA0 AQEPPGSQQPLQSLEEEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 AQEPPGSQQPLQSLEEEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHC
700 710 720 730 740 750
810 820 830 840 850 860
pF1KA0 ASDGSTETLAMVVVEPGDTLSSPEFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 ASDGSTETLAMVVVEPGDTLSSPEFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVDG
760 770 780 790 800 810
870 880 890 900 910 920
pF1KA0 RSCSMDSAYGTLSPTSLQDFVAPGPMAELVPRAPESPRVPSPPPSPRLRRRTPVQLLSCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 RSCSMDSAYGTLSPTSLQDFVAPGPMAELVPRAPESPRVPSPPPSPRLRRRTPVQLLSCP
820 830 840 850 860 870
930 940 950 960 970 980
pF1KA0 PHLLKSKSEASLLQLLAGAGTHGTPSAPSRSLSELCLAVPAPGIRTQGSPQEAGPSWDCR
::::::::::::::::::::::::::::::::::::::::::. ...: : :. :
CCDS57 PHLLKSKSEASLLQLLAGAGTHGTPSAPSRSLSELCLAVPAPA--QEADPGPALPNQDHP
880 890 900 910 920
990 1000 1010 1020 1030 1040
pF1KA0 GAPSPGSGPGLVGCLAGEPAGSHRKRCGDLPSGASPRVQPEPPPGVSAQHRKLTLAQLYR
CCDS57 AA
930
>>CCDS44808.1 PLEKHG6 gene_id:55200|Hs108|chr12 (758 aa)
initn: 1467 init1: 1272 opt: 1391 Z-score: 823.4 bits: 163.6 E(32554): 1.5e-39
Smith-Waterman score: 1458; 36.7% identity (62.0% similar) in 768 aa overlap (305-1062:50-758)
280 290 300 310 320 330
pF1KA0 EPPTPSSCSLPSGSSGSTNSGDSWKNRAASRFSGFFSSGPSTSAFGREVDKMEQLEGKLH
: .: ..: : .:. : ..:: .::
CCDS44 RLQQYVPFARGSGQARGLSPMRLRDPEPEKRHGGHVGAGLLHSPKLKELTKAHELEVRLH
20 30 40 50 60 70
340 350 360 370 380 390
pF1KA0 TYSLFGLPRLPRGLRFDHDSWEEEYDEDEDEDNACLRLEDSWRELIDGHEKLTRRQCHQQ
:.:.::.:::: :. :: : :.. : .: :::::. ::...... ::::
CCDS44 TFSMFGMPRLP---PEDRRHWEI----GEGGDSG-LTIEKSWRELVPGHKEMSQELCHQQ
80 90 100 110 120 130
400 410 420 430 440 450
pF1KA0 EAVWELLHTEASYIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNIPEIAQLHRRLW
::.:::: :: :.:::... .:. :::::. ::: :: :: ::.:.: . . :: .:
CCDS44 EALWELLTTELIYVRKLKIMTDLLAAGLLNLQRVGLLMEVSAETLFGNVPSLIRTHRSFW
140 150 160 170 180 190
460 470 480 490 500 510
pF1KA0 ASVMAPVLEKARRTRALLQPGDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDL
:..:.::..: . :.: . .:: ::. :.::..::.. . : : : . : :
CCDS44 DEVLGPTLEETRASGQPLDPIGLQSGFLTFGQRFHPYVQYCLRVKQTMAYAREQQETNPL
200 210 220 230 240 250
520 530 540 550 560 570
pF1KA0 FRAYITWAEKHPQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTEEPRAKEAVVAMIGSV
:.:.. : ::: . : : :.: :::::.:::::::..::... : ::.::. ::: .:
CCDS44 FHAFVQWCEKHKRSGRQMLCDLLIKPHQRITKYPLLLHAVLKRSPEARAQEALNAMIEAV
260 270 280 290 300 310
580 590 600 610 620 630
pF1KA0 ERFIHHVNACMRQRQERQRLAAVVSRIDAYEVVESSSDEVDKLLKEFLHLDLTAPIPGAS
: :..:.:. .:: .:.. :::...:: :::.: ::::.: :. : ::::.:. :..
CCDS44 ESFLRHINGQVRQGEEQESLAAAAQRIGPYEVLEPPSDEVEKNLRPFSTLDLTSPMLGVA
320 330 340 350 360 370
640 650 660 670 680 690
pF1KA0 PEETRQLLLEGSLRMKEGKDSKMDVYCFLFTDLLLVTKAVKKAERTRVIRPPLLVDKIVC
:.:::::::: .:.:::...:.::: :::.:.::::: .::....::::::...:.::
CCDS44 SEHTRQLLLEGPVRVKEGREGKLDVYLFLFSDVLLVTKPQRKADKAKVIRPPLMLEKLVC
380 390 400 410 420 430
700 710 720 730 740 750
pF1KA0 RELRDPGSFLLIYLNEFHSAVGAYTFQASGQALCRGWVDTIYNAQNQLQQLRAQEPPGSQ
. ::::.:::::.:.::. . .: . . . :.. .:: ::.:.:.: ..
CCDS44 QPLRDPNSFLLIHLTEFQCVSSALLVHCPSPTDRAQWLEKTQQAQAALQKLKAEEYVQQK
440 450 460 470 480 490
760 770 780 790 800 810
pF1KA0 QPLQSLEEEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASDGSTET
. : .: ...:.. ::. : :. : .... ...: :
CCDS44 RELLTLYRDQDRE----------------------SPST-RPSTPSLEGSQSSAEGRTPE
500 510 520
820 830 840 850 860 870
pF1KA0 LAMVVVEPGDTLSSPEFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVDGRSCSMDSA
.. .. : ... ...:. .. : : .:::. ::. . :. :
CCDS44 FSTII--PHLVVTEDTDEDAPLVPDDTSDSGYGTLIPGTPTGSRSPLSRLRQRALRRDPR
530 540 550 560 570 580
880 890 900 910 920 930
pF1KA0 YGTLSPTSLQDFVAPGPMAELVPRAPESPRVPSPPPSPRLRRRTPVQLLSCPPHLLKSKS
:.: :.:. :. : :..:. : : :. . :: . ..
CCDS44 L-TFSTLELRDI----PLRPHPPD-PQAPQRRSAPELPEGILKGGSLPQEDPPTWSEEED
590 600 610 620 630 640
940 950 960 970 980
pF1KA0 EAS-----LLQLLAGAGTHGT-PSAPSRSLSELCLAVPAPGIRTQGSPQEAGPSWDCRGA
:: ... : : .: ::.:... : : .: ...: .: :: . :
CCDS44 GASERGNVVVETLHRARLRGQLPSSPTHADS----AGESPW-ESSGEEEEEGPLFLKAGH
650 660 670 680 690
990 1000 1010 1020 1030 1040
pF1KA0 PS--PGSGPGLVGCLAGEPAGSHRKRCGDLPSGASPRVQPEPPPGVSAQHRKLTLAQLYR
: : . .. . : : :.: . .. : . :: ::: ::: :
CCDS44 TSLRPMRAEDMLREIREELA-SQRIEGAEEPRDSRPR--------------KLTRAQLQR
700 710 720 730 740
1050 1060
pF1KA0 IRTT--LLLNSTLTASEV
.: . :.. :.::::
CCDS44 MRGPHIIQLDTPLSASEV
750
>>CCDS8541.1 PLEKHG6 gene_id:55200|Hs108|chr12 (790 aa)
initn: 1435 init1: 1272 opt: 1391 Z-score: 823.1 bits: 163.6 E(32554): 1.6e-39
Smith-Waterman score: 1458; 36.7% identity (62.0% similar) in 768 aa overlap (305-1062:82-790)
280 290 300 310 320 330
pF1KA0 EPPTPSSCSLPSGSSGSTNSGDSWKNRAASRFSGFFSSGPSTSAFGREVDKMEQLEGKLH
: .: ..: : .:. : ..:: .::
CCDS85 RLQQYVPFARGSGQARGLSPMRLRDPEPEKRHGGHVGAGLLHSPKLKELTKAHELEVRLH
60 70 80 90 100 110
340 350 360 370 380 390
pF1KA0 TYSLFGLPRLPRGLRFDHDSWEEEYDEDEDEDNACLRLEDSWRELIDGHEKLTRRQCHQQ
:.:.::.:::: :. :: : :.. : .: :::::. ::...... ::::
CCDS85 TFSMFGMPRLP---PEDRRHWEI----GEGGDSG-LTIEKSWRELVPGHKEMSQELCHQQ
120 130 140 150 160
400 410 420 430 440 450
pF1KA0 EAVWELLHTEASYIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNIPEIAQLHRRLW
::.:::: :: :.:::... .:. :::::. ::: :: :: ::.:.: . . :: .:
CCDS85 EALWELLTTELIYVRKLKIMTDLLAAGLLNLQRVGLLMEVSAETLFGNVPSLIRTHRSFW
170 180 190 200 210 220
460 470 480 490 500 510
pF1KA0 ASVMAPVLEKARRTRALLQPGDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDL
:..:.::..: . :.: . .:: ::. :.::..::.. . : : : . : :
CCDS85 DEVLGPTLEETRASGQPLDPIGLQSGFLTFGQRFHPYVQYCLRVKQTMAYAREQQETNPL
230 240 250 260 270 280
520 530 540 550 560 570
pF1KA0 FRAYITWAEKHPQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTEEPRAKEAVVAMIGSV
:.:.. : ::: . : : :.: :::::.:::::::..::... : ::.::. ::: .:
CCDS85 FHAFVQWCEKHKRSGRQMLCDLLIKPHQRITKYPLLLHAVLKRSPEARAQEALNAMIEAV
290 300 310 320 330 340
580 590 600 610 620 630
pF1KA0 ERFIHHVNACMRQRQERQRLAAVVSRIDAYEVVESSSDEVDKLLKEFLHLDLTAPIPGAS
: :..:.:. .:: .:.. :::...:: :::.: ::::.: :. : ::::.:. :..
CCDS85 ESFLRHINGQVRQGEEQESLAAAAQRIGPYEVLEPPSDEVEKNLRPFSTLDLTSPMLGVA
350 360 370 380 390 400
640 650 660 670 680 690
pF1KA0 PEETRQLLLEGSLRMKEGKDSKMDVYCFLFTDLLLVTKAVKKAERTRVIRPPLLVDKIVC
:.:::::::: .:.:::...:.::: :::.:.::::: .::....::::::...:.::
CCDS85 SEHTRQLLLEGPVRVKEGREGKLDVYLFLFSDVLLVTKPQRKADKAKVIRPPLMLEKLVC
410 420 430 440 450 460
700 710 720 730 740 750
pF1KA0 RELRDPGSFLLIYLNEFHSAVGAYTFQASGQALCRGWVDTIYNAQNQLQQLRAQEPPGSQ
. ::::.:::::.:.::. . .: . . . :.. .:: ::.:.:.: ..
CCDS85 QPLRDPNSFLLIHLTEFQCVSSALLVHCPSPTDRAQWLEKTQQAQAALQKLKAEEYVQQK
470 480 490 500 510 520
760 770 780 790 800 810
pF1KA0 QPLQSLEEEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASDGSTET
. : .: ...:.. ::. : :. : .... ...: :
CCDS85 RELLTLYRDQDRE----------------------SPST-RPSTPSLEGSQSSAEGRTPE
530 540 550 560
820 830 840 850 860 870
pF1KA0 LAMVVVEPGDTLSSPEFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVDGRSCSMDSA
.. .. : ... ...:. .. : : .:::. ::. . :. :
CCDS85 FSTII--PHLVVTEDTDEDAPLVPDDTSDSGYGTLIPGTPTGSRSPLSRLRQRALRRDPR
570 580 590 600 610
880 890 900 910 920 930
pF1KA0 YGTLSPTSLQDFVAPGPMAELVPRAPESPRVPSPPPSPRLRRRTPVQLLSCPPHLLKSKS
:.: :.:. :. : :..:. : : :. . :: . ..
CCDS85 L-TFSTLELRDI----PLRPHPPD-PQAPQRRSAPELPEGILKGGSLPQEDPPTWSEEED
620 630 640 650 660 670
940 950 960 970 980
pF1KA0 EAS-----LLQLLAGAGTHGT-PSAPSRSLSELCLAVPAPGIRTQGSPQEAGPSWDCRGA
:: ... : : .: ::.:... : : .: ...: .: :: . :
CCDS85 GASERGNVVVETLHRARLRGQLPSSPTHADS----AGESPW-ESSGEEEEEGPLFLKAGH
680 690 700 710 720
990 1000 1010 1020 1030 1040
pF1KA0 PS--PGSGPGLVGCLAGEPAGSHRKRCGDLPSGASPRVQPEPPPGVSAQHRKLTLAQLYR
: : . .. . : : :.: . .. : . :: ::: ::: :
CCDS85 TSLRPMRAEDMLREIREELA-SQRIEGAEEPRDSRPR--------------KLTRAQLQR
730 740 750 760 770
1050 1060
pF1KA0 IRTT--LLLNSTLTASEV
.: . :.. :.::::
CCDS85 MRGPHIIQLDTPLSASEV
780 790
1062 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 10:05:27 2016 done: Thu Nov 3 10:05:28 2016
Total Scan time: 6.020 Total Display time: 0.370
Function used was FASTA [36.3.4 Apr, 2011]