Result of FASTA (omim) for
pF1KA0675
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0675, 1208 aa
1>>>pF1KA0675 1208 - 1208 aa - 1208 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.4187+/-0.0004; mu= 10.6657+/- 0.025
mean_var=243.3426+/-50.316, 0's: 0 Z-trim(119.7): 114 B-trim: 390 in 2/54
Lambda= 0.082218
statistics sampled from 33954 (34111) to 33954 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.718), E-opt: 0.2 (0.4), width: 16
Scan time: 16.270
The best scores are: opt bits E(85289)
XP_005247975 (OMIM: 608672) PREDICTED: E3 ubiquiti (1208) 8093 974.2 0
NP_055463 (OMIM: 608672) E3 ubiquitin-protein liga (1208) 8093 974.2 0
XP_005247972 (OMIM: 608672) PREDICTED: E3 ubiquiti (1208) 8093 974.2 0
XP_005247974 (OMIM: 608672) PREDICTED: E3 ubiquiti (1208) 8093 974.2 0
XP_005247971 (OMIM: 608672) PREDICTED: E3 ubiquiti (1208) 8093 974.2 0
XP_016863029 (OMIM: 608672) PREDICTED: E3 ubiquiti (1208) 8093 974.2 0
XP_005247973 (OMIM: 608672) PREDICTED: E3 ubiquiti (1208) 8093 974.2 0
XP_005247976 (OMIM: 608672) PREDICTED: E3 ubiquiti (1002) 4182 510.2 2.6e-143
NP_001317611 (OMIM: 602259) E3 ubiquitin-protein l (1715) 333 53.9 1e-05
NP_001317610 (OMIM: 602259) E3 ubiquitin-protein l (1715) 333 53.9 1e-05
XP_016883954 (OMIM: 602259) PREDICTED: E3 ubiquiti (1733) 333 53.9 1e-05
XP_005261112 (OMIM: 602259) PREDICTED: E3 ubiquiti (1733) 333 53.9 1e-05
XP_005261113 (OMIM: 602259) PREDICTED: E3 ubiquiti (1733) 333 53.9 1e-05
XP_016883953 (OMIM: 602259) PREDICTED: E3 ubiquiti (1782) 333 54.0 1.1e-05
XP_011528042 (OMIM: 602259) PREDICTED: E3 ubiquiti (1792) 333 54.0 1.1e-05
XP_011528041 (OMIM: 602259) PREDICTED: E3 ubiquiti (1810) 333 54.0 1.1e-05
NP_003307 (OMIM: 602259) E3 ubiquitin-protein liga (2025) 333 54.0 1.2e-05
NP_001001894 (OMIM: 602259) E3 ubiquitin-protein l (2025) 333 54.0 1.2e-05
NP_001317612 (OMIM: 602259) E3 ubiquitin-protein l (2025) 333 54.0 1.2e-05
XP_016883950 (OMIM: 602259) PREDICTED: E3 ubiquiti (2041) 333 54.0 1.2e-05
XP_016883951 (OMIM: 602259) PREDICTED: E3 ubiquiti (2041) 333 54.0 1.2e-05
XP_005261111 (OMIM: 602259) PREDICTED: E3 ubiquiti (2043) 333 54.0 1.2e-05
XP_005261109 (OMIM: 602259) PREDICTED: E3 ubiquiti (2043) 333 54.0 1.2e-05
NP_001307633 (OMIM: 602259) E3 ubiquitin-protein l (2043) 333 54.0 1.2e-05
XP_016883949 (OMIM: 602259) PREDICTED: E3 ubiquiti (2047) 333 54.0 1.2e-05
XP_005261107 (OMIM: 602259) PREDICTED: E3 ubiquiti (2059) 333 54.0 1.2e-05
XP_005261105 (OMIM: 602259) PREDICTED: E3 ubiquiti (2059) 333 54.0 1.2e-05
XP_005261106 (OMIM: 602259) PREDICTED: E3 ubiquiti (2059) 333 54.0 1.2e-05
XP_016883948 (OMIM: 602259) PREDICTED: E3 ubiquiti (2063) 333 54.0 1.2e-05
NP_001307632 (OMIM: 602259) E3 ubiquitin-protein l (2065) 333 54.0 1.2e-05
XP_016883947 (OMIM: 602259) PREDICTED: E3 ubiquiti (2081) 333 54.0 1.2e-05
XP_011528044 (OMIM: 602259) PREDICTED: E3 ubiquiti (1059) 296 49.3 0.00015
>>XP_005247975 (OMIM: 608672) PREDICTED: E3 ubiquitin-pr (1208 aa)
initn: 8093 init1: 8093 opt: 8093 Z-score: 5200.0 bits: 974.2 E(85289): 0
Smith-Waterman score: 8093; 100.0% identity (100.0% similar) in 1208 aa overlap (1-1208:1-1208)
10 20 30 40 50 60
pF1KA0 MDSLPDEFFVRHPAVEDQRKEETENKLEKSSGQLNKQENDIPTDLVPVNLLLEVKKLLNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDSLPDEFFVRHPAVEDQRKEETENKLEKSSGQLNKQENDIPTDLVPVNLLLEVKKLLNA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 INTLPKGVVPHIKKFLQEDFSFQTMQREVAANSQNGEEIVPALTLRFLITQLEAALRNIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 INTLPKGVVPHIKKFLQEDFSFQTMQREVAANSQNGEEIVPALTLRFLITQLEAALRNIQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 AGNYTAHQINIGYYLTLLFLYGVALTERGKKEDYTEAENKFLVMKMMIQENEICENFMSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGNYTAHQINIGYYLTLLFLYGVALTERGKKEDYTEAENKFLVMKMMIQENEICENFMSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 VYFGRGLLRCAQKRYNGGLLEFHKSLQEIGDKNDHWFDIDPTEDEDLPTTFKDLLNNFIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VYFGRGLLRCAQKRYNGGLLEFHKSLQEIGDKNDHWFDIDPTEDEDLPTTFKDLLNNFIK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 TTESNIMKQTICSYLDCERSCEADILKNTSYKGFFQLMCSKSCCVYFHKICWKKFKNLKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TTESNIMKQTICSYLDCERSCEADILKNTSYKGFFQLMCSKSCCVYFHKICWKKFKNLKY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PGENDQSFSGKKCLKEGCTGDMVRMLQCDVPGIVKILFEVVRKDEYITIENLGASYRKLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGENDQSFSGKKCLKEGCTGDMVRMLQCDVPGIVKILFEVVRKDEYITIENLGASYRKLI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 SLKITDTDIRPKISLKFNTKDEMPIFKLDYNYFYHLLHIIIISGTDIVRQIFDEAMPPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLKITDTDIRPKISLKFNTKDEMPIFKLDYNYFYHLLHIIIISGTDIVRQIFDEAMPPPL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 LKKELLIHKNVLESYYNHLWTNHPLGGSWHLLYPPNKELPQSKQFDLCLLLALIKHLNVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKKELLIHKNVLESYYNHLWTNHPLGGSWHLLYPPNKELPQSKQFDLCLLLALIKHLNVF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 PAPKKGWNMEPPSSDISKSADILRLCKYRDILLSEILMNGLTESQFNSIWKKVSDILLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PAPKKGWNMEPPSSDISKSADILRLCKYRDILLSEILMNGLTESQFNSIWKKVSDILLRL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 GMMQEDIDKVKENPIENISLDYHQLSVYLGIPVPEIIQRMLSCYQQGIALQSITGSQRIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GMMQEDIDKVKENPIENISLDYHQLSVYLGIPVPEIIQRMLSCYQQGIALQSITGSQRIE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 IEELQNEEEELSPPLMEYNINVKSHPEIQFAEINKDGTSIPSESSTESLKDLQEVKSKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEELQNEEEELSPPLMEYNINVKSHPEIQFAEINKDGTSIPSESSTESLKDLQEVKSKQR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 KKKKTKNKKNKDSKEDQVPYVVEKEEQLRKEQANPHSVSRLIKDDASDVQEDSAMEDKFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKKKTKNKKNKDSKEDQVPYVVEKEEQLRKEQANPHSVSRLIKDDASDVQEDSAMEDKFY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 SLDELHILDMIEQGSAGKVTTDYGETEKERLARQRQLYKLHYQCEDFKRQLRTVTFRWQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLDELHILDMIEQGSAGKVTTDYGETEKERLARQRQLYKLHYQCEDFKRQLRTVTFRWQE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 NQMQIKKKDKIIASLNQQVAFGINKVSKLQRQIHAKDNEIKNLKEQLSMKRSQWEMEKHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQMQIKKKDKIIASLNQQVAFGINKVSKLQRQIHAKDNEIKNLKEQLSMKRSQWEMEKHN
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 LESTMKTYVSKLNAETSRALTAEVYFLQCRRDFGLLHLEQTEKECLNQLARVTHMAASNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LESTMKTYVSKLNAETSRALTAEVYFLQCRRDFGLLHLEQTEKECLNQLARVTHMAASNL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 ESLQLKAAVDSWNAIVADVRNKIAFLRTQYNEQINKVKQGFALSTLPPVQLPPPPPSPEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESLQLKAAVDSWNAIVADVRNKIAFLRTQYNEQINKVKQGFALSTLPPVQLPPPPPSPEI
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LMQQFLGRPLVKESFFRPILTVPQMPAVCPGVVSATGQPRAPLMTGIAWALPAPVGDAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LMQQFLGRPLVKESFFRPILTVPQMPAVCPGVVSATGQPRAPLMTGIAWALPAPVGDAVP
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 PSAGLRSDPSIMNWERITDRLKTAFPQQTRKELTDFLRKLKDAYGKSLSELTFDEIVCKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSAGLRSDPSIMNWERITDRLKTAFPQQTRKELTDFLRKLKDAYGKSLSELTFDEIVCKI
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 SQFIDPKKSQSQGKSVSNVNCVSPSHSPSQPDAAQPPKPAWRPLTSQGPATWEGASNPDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQFIDPKKSQSQGKSVSNVNCVSPSHSPSQPDAAQPPKPAWRPLTSQGPATWEGASNPDE
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 EEEEEEPCVICHENLSPENLSVLPCAHKFHAQCIRPWLMQQGTCPTCRLHVLLPEEFPGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEEEEEPCVICHENLSPENLSVLPCAHKFHAQCIRPWLMQQGTCPTCRLHVLLPEEFPGH
1150 1160 1170 1180 1190 1200
pF1KA0 PSRQLPKI
::::::::
XP_005 PSRQLPKI
>>NP_055463 (OMIM: 608672) E3 ubiquitin-protein ligase D (1208 aa)
initn: 8093 init1: 8093 opt: 8093 Z-score: 5200.0 bits: 974.2 E(85289): 0
Smith-Waterman score: 8093; 100.0% identity (100.0% similar) in 1208 aa overlap (1-1208:1-1208)
10 20 30 40 50 60
pF1KA0 MDSLPDEFFVRHPAVEDQRKEETENKLEKSSGQLNKQENDIPTDLVPVNLLLEVKKLLNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MDSLPDEFFVRHPAVEDQRKEETENKLEKSSGQLNKQENDIPTDLVPVNLLLEVKKLLNA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 INTLPKGVVPHIKKFLQEDFSFQTMQREVAANSQNGEEIVPALTLRFLITQLEAALRNIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 INTLPKGVVPHIKKFLQEDFSFQTMQREVAANSQNGEEIVPALTLRFLITQLEAALRNIQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 AGNYTAHQINIGYYLTLLFLYGVALTERGKKEDYTEAENKFLVMKMMIQENEICENFMSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AGNYTAHQINIGYYLTLLFLYGVALTERGKKEDYTEAENKFLVMKMMIQENEICENFMSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 VYFGRGLLRCAQKRYNGGLLEFHKSLQEIGDKNDHWFDIDPTEDEDLPTTFKDLLNNFIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VYFGRGLLRCAQKRYNGGLLEFHKSLQEIGDKNDHWFDIDPTEDEDLPTTFKDLLNNFIK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 TTESNIMKQTICSYLDCERSCEADILKNTSYKGFFQLMCSKSCCVYFHKICWKKFKNLKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TTESNIMKQTICSYLDCERSCEADILKNTSYKGFFQLMCSKSCCVYFHKICWKKFKNLKY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PGENDQSFSGKKCLKEGCTGDMVRMLQCDVPGIVKILFEVVRKDEYITIENLGASYRKLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PGENDQSFSGKKCLKEGCTGDMVRMLQCDVPGIVKILFEVVRKDEYITIENLGASYRKLI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 SLKITDTDIRPKISLKFNTKDEMPIFKLDYNYFYHLLHIIIISGTDIVRQIFDEAMPPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SLKITDTDIRPKISLKFNTKDEMPIFKLDYNYFYHLLHIIIISGTDIVRQIFDEAMPPPL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 LKKELLIHKNVLESYYNHLWTNHPLGGSWHLLYPPNKELPQSKQFDLCLLLALIKHLNVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LKKELLIHKNVLESYYNHLWTNHPLGGSWHLLYPPNKELPQSKQFDLCLLLALIKHLNVF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 PAPKKGWNMEPPSSDISKSADILRLCKYRDILLSEILMNGLTESQFNSIWKKVSDILLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PAPKKGWNMEPPSSDISKSADILRLCKYRDILLSEILMNGLTESQFNSIWKKVSDILLRL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 GMMQEDIDKVKENPIENISLDYHQLSVYLGIPVPEIIQRMLSCYQQGIALQSITGSQRIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GMMQEDIDKVKENPIENISLDYHQLSVYLGIPVPEIIQRMLSCYQQGIALQSITGSQRIE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 IEELQNEEEELSPPLMEYNINVKSHPEIQFAEINKDGTSIPSESSTESLKDLQEVKSKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IEELQNEEEELSPPLMEYNINVKSHPEIQFAEINKDGTSIPSESSTESLKDLQEVKSKQR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 KKKKTKNKKNKDSKEDQVPYVVEKEEQLRKEQANPHSVSRLIKDDASDVQEDSAMEDKFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KKKKTKNKKNKDSKEDQVPYVVEKEEQLRKEQANPHSVSRLIKDDASDVQEDSAMEDKFY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 SLDELHILDMIEQGSAGKVTTDYGETEKERLARQRQLYKLHYQCEDFKRQLRTVTFRWQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SLDELHILDMIEQGSAGKVTTDYGETEKERLARQRQLYKLHYQCEDFKRQLRTVTFRWQE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 NQMQIKKKDKIIASLNQQVAFGINKVSKLQRQIHAKDNEIKNLKEQLSMKRSQWEMEKHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NQMQIKKKDKIIASLNQQVAFGINKVSKLQRQIHAKDNEIKNLKEQLSMKRSQWEMEKHN
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 LESTMKTYVSKLNAETSRALTAEVYFLQCRRDFGLLHLEQTEKECLNQLARVTHMAASNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LESTMKTYVSKLNAETSRALTAEVYFLQCRRDFGLLHLEQTEKECLNQLARVTHMAASNL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 ESLQLKAAVDSWNAIVADVRNKIAFLRTQYNEQINKVKQGFALSTLPPVQLPPPPPSPEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ESLQLKAAVDSWNAIVADVRNKIAFLRTQYNEQINKVKQGFALSTLPPVQLPPPPPSPEI
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LMQQFLGRPLVKESFFRPILTVPQMPAVCPGVVSATGQPRAPLMTGIAWALPAPVGDAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LMQQFLGRPLVKESFFRPILTVPQMPAVCPGVVSATGQPRAPLMTGIAWALPAPVGDAVP
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 PSAGLRSDPSIMNWERITDRLKTAFPQQTRKELTDFLRKLKDAYGKSLSELTFDEIVCKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PSAGLRSDPSIMNWERITDRLKTAFPQQTRKELTDFLRKLKDAYGKSLSELTFDEIVCKI
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 SQFIDPKKSQSQGKSVSNVNCVSPSHSPSQPDAAQPPKPAWRPLTSQGPATWEGASNPDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SQFIDPKKSQSQGKSVSNVNCVSPSHSPSQPDAAQPPKPAWRPLTSQGPATWEGASNPDE
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 EEEEEEPCVICHENLSPENLSVLPCAHKFHAQCIRPWLMQQGTCPTCRLHVLLPEEFPGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EEEEEEPCVICHENLSPENLSVLPCAHKFHAQCIRPWLMQQGTCPTCRLHVLLPEEFPGH
1150 1160 1170 1180 1190 1200
pF1KA0 PSRQLPKI
::::::::
NP_055 PSRQLPKI
>>XP_005247972 (OMIM: 608672) PREDICTED: E3 ubiquitin-pr (1208 aa)
initn: 8093 init1: 8093 opt: 8093 Z-score: 5200.0 bits: 974.2 E(85289): 0
Smith-Waterman score: 8093; 100.0% identity (100.0% similar) in 1208 aa overlap (1-1208:1-1208)
10 20 30 40 50 60
pF1KA0 MDSLPDEFFVRHPAVEDQRKEETENKLEKSSGQLNKQENDIPTDLVPVNLLLEVKKLLNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDSLPDEFFVRHPAVEDQRKEETENKLEKSSGQLNKQENDIPTDLVPVNLLLEVKKLLNA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 INTLPKGVVPHIKKFLQEDFSFQTMQREVAANSQNGEEIVPALTLRFLITQLEAALRNIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 INTLPKGVVPHIKKFLQEDFSFQTMQREVAANSQNGEEIVPALTLRFLITQLEAALRNIQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 AGNYTAHQINIGYYLTLLFLYGVALTERGKKEDYTEAENKFLVMKMMIQENEICENFMSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGNYTAHQINIGYYLTLLFLYGVALTERGKKEDYTEAENKFLVMKMMIQENEICENFMSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 VYFGRGLLRCAQKRYNGGLLEFHKSLQEIGDKNDHWFDIDPTEDEDLPTTFKDLLNNFIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VYFGRGLLRCAQKRYNGGLLEFHKSLQEIGDKNDHWFDIDPTEDEDLPTTFKDLLNNFIK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 TTESNIMKQTICSYLDCERSCEADILKNTSYKGFFQLMCSKSCCVYFHKICWKKFKNLKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TTESNIMKQTICSYLDCERSCEADILKNTSYKGFFQLMCSKSCCVYFHKICWKKFKNLKY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PGENDQSFSGKKCLKEGCTGDMVRMLQCDVPGIVKILFEVVRKDEYITIENLGASYRKLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGENDQSFSGKKCLKEGCTGDMVRMLQCDVPGIVKILFEVVRKDEYITIENLGASYRKLI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 SLKITDTDIRPKISLKFNTKDEMPIFKLDYNYFYHLLHIIIISGTDIVRQIFDEAMPPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLKITDTDIRPKISLKFNTKDEMPIFKLDYNYFYHLLHIIIISGTDIVRQIFDEAMPPPL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 LKKELLIHKNVLESYYNHLWTNHPLGGSWHLLYPPNKELPQSKQFDLCLLLALIKHLNVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKKELLIHKNVLESYYNHLWTNHPLGGSWHLLYPPNKELPQSKQFDLCLLLALIKHLNVF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 PAPKKGWNMEPPSSDISKSADILRLCKYRDILLSEILMNGLTESQFNSIWKKVSDILLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PAPKKGWNMEPPSSDISKSADILRLCKYRDILLSEILMNGLTESQFNSIWKKVSDILLRL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 GMMQEDIDKVKENPIENISLDYHQLSVYLGIPVPEIIQRMLSCYQQGIALQSITGSQRIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GMMQEDIDKVKENPIENISLDYHQLSVYLGIPVPEIIQRMLSCYQQGIALQSITGSQRIE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 IEELQNEEEELSPPLMEYNINVKSHPEIQFAEINKDGTSIPSESSTESLKDLQEVKSKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEELQNEEEELSPPLMEYNINVKSHPEIQFAEINKDGTSIPSESSTESLKDLQEVKSKQR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 KKKKTKNKKNKDSKEDQVPYVVEKEEQLRKEQANPHSVSRLIKDDASDVQEDSAMEDKFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKKKTKNKKNKDSKEDQVPYVVEKEEQLRKEQANPHSVSRLIKDDASDVQEDSAMEDKFY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 SLDELHILDMIEQGSAGKVTTDYGETEKERLARQRQLYKLHYQCEDFKRQLRTVTFRWQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLDELHILDMIEQGSAGKVTTDYGETEKERLARQRQLYKLHYQCEDFKRQLRTVTFRWQE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 NQMQIKKKDKIIASLNQQVAFGINKVSKLQRQIHAKDNEIKNLKEQLSMKRSQWEMEKHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQMQIKKKDKIIASLNQQVAFGINKVSKLQRQIHAKDNEIKNLKEQLSMKRSQWEMEKHN
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 LESTMKTYVSKLNAETSRALTAEVYFLQCRRDFGLLHLEQTEKECLNQLARVTHMAASNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LESTMKTYVSKLNAETSRALTAEVYFLQCRRDFGLLHLEQTEKECLNQLARVTHMAASNL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 ESLQLKAAVDSWNAIVADVRNKIAFLRTQYNEQINKVKQGFALSTLPPVQLPPPPPSPEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESLQLKAAVDSWNAIVADVRNKIAFLRTQYNEQINKVKQGFALSTLPPVQLPPPPPSPEI
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LMQQFLGRPLVKESFFRPILTVPQMPAVCPGVVSATGQPRAPLMTGIAWALPAPVGDAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LMQQFLGRPLVKESFFRPILTVPQMPAVCPGVVSATGQPRAPLMTGIAWALPAPVGDAVP
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 PSAGLRSDPSIMNWERITDRLKTAFPQQTRKELTDFLRKLKDAYGKSLSELTFDEIVCKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSAGLRSDPSIMNWERITDRLKTAFPQQTRKELTDFLRKLKDAYGKSLSELTFDEIVCKI
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 SQFIDPKKSQSQGKSVSNVNCVSPSHSPSQPDAAQPPKPAWRPLTSQGPATWEGASNPDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQFIDPKKSQSQGKSVSNVNCVSPSHSPSQPDAAQPPKPAWRPLTSQGPATWEGASNPDE
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 EEEEEEPCVICHENLSPENLSVLPCAHKFHAQCIRPWLMQQGTCPTCRLHVLLPEEFPGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEEEEEPCVICHENLSPENLSVLPCAHKFHAQCIRPWLMQQGTCPTCRLHVLLPEEFPGH
1150 1160 1170 1180 1190 1200
pF1KA0 PSRQLPKI
::::::::
XP_005 PSRQLPKI
>>XP_005247974 (OMIM: 608672) PREDICTED: E3 ubiquitin-pr (1208 aa)
initn: 8093 init1: 8093 opt: 8093 Z-score: 5200.0 bits: 974.2 E(85289): 0
Smith-Waterman score: 8093; 100.0% identity (100.0% similar) in 1208 aa overlap (1-1208:1-1208)
10 20 30 40 50 60
pF1KA0 MDSLPDEFFVRHPAVEDQRKEETENKLEKSSGQLNKQENDIPTDLVPVNLLLEVKKLLNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDSLPDEFFVRHPAVEDQRKEETENKLEKSSGQLNKQENDIPTDLVPVNLLLEVKKLLNA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 INTLPKGVVPHIKKFLQEDFSFQTMQREVAANSQNGEEIVPALTLRFLITQLEAALRNIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 INTLPKGVVPHIKKFLQEDFSFQTMQREVAANSQNGEEIVPALTLRFLITQLEAALRNIQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 AGNYTAHQINIGYYLTLLFLYGVALTERGKKEDYTEAENKFLVMKMMIQENEICENFMSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGNYTAHQINIGYYLTLLFLYGVALTERGKKEDYTEAENKFLVMKMMIQENEICENFMSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 VYFGRGLLRCAQKRYNGGLLEFHKSLQEIGDKNDHWFDIDPTEDEDLPTTFKDLLNNFIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VYFGRGLLRCAQKRYNGGLLEFHKSLQEIGDKNDHWFDIDPTEDEDLPTTFKDLLNNFIK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 TTESNIMKQTICSYLDCERSCEADILKNTSYKGFFQLMCSKSCCVYFHKICWKKFKNLKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TTESNIMKQTICSYLDCERSCEADILKNTSYKGFFQLMCSKSCCVYFHKICWKKFKNLKY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PGENDQSFSGKKCLKEGCTGDMVRMLQCDVPGIVKILFEVVRKDEYITIENLGASYRKLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGENDQSFSGKKCLKEGCTGDMVRMLQCDVPGIVKILFEVVRKDEYITIENLGASYRKLI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 SLKITDTDIRPKISLKFNTKDEMPIFKLDYNYFYHLLHIIIISGTDIVRQIFDEAMPPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLKITDTDIRPKISLKFNTKDEMPIFKLDYNYFYHLLHIIIISGTDIVRQIFDEAMPPPL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 LKKELLIHKNVLESYYNHLWTNHPLGGSWHLLYPPNKELPQSKQFDLCLLLALIKHLNVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKKELLIHKNVLESYYNHLWTNHPLGGSWHLLYPPNKELPQSKQFDLCLLLALIKHLNVF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 PAPKKGWNMEPPSSDISKSADILRLCKYRDILLSEILMNGLTESQFNSIWKKVSDILLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PAPKKGWNMEPPSSDISKSADILRLCKYRDILLSEILMNGLTESQFNSIWKKVSDILLRL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 GMMQEDIDKVKENPIENISLDYHQLSVYLGIPVPEIIQRMLSCYQQGIALQSITGSQRIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GMMQEDIDKVKENPIENISLDYHQLSVYLGIPVPEIIQRMLSCYQQGIALQSITGSQRIE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 IEELQNEEEELSPPLMEYNINVKSHPEIQFAEINKDGTSIPSESSTESLKDLQEVKSKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEELQNEEEELSPPLMEYNINVKSHPEIQFAEINKDGTSIPSESSTESLKDLQEVKSKQR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 KKKKTKNKKNKDSKEDQVPYVVEKEEQLRKEQANPHSVSRLIKDDASDVQEDSAMEDKFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKKKTKNKKNKDSKEDQVPYVVEKEEQLRKEQANPHSVSRLIKDDASDVQEDSAMEDKFY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 SLDELHILDMIEQGSAGKVTTDYGETEKERLARQRQLYKLHYQCEDFKRQLRTVTFRWQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLDELHILDMIEQGSAGKVTTDYGETEKERLARQRQLYKLHYQCEDFKRQLRTVTFRWQE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 NQMQIKKKDKIIASLNQQVAFGINKVSKLQRQIHAKDNEIKNLKEQLSMKRSQWEMEKHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQMQIKKKDKIIASLNQQVAFGINKVSKLQRQIHAKDNEIKNLKEQLSMKRSQWEMEKHN
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 LESTMKTYVSKLNAETSRALTAEVYFLQCRRDFGLLHLEQTEKECLNQLARVTHMAASNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LESTMKTYVSKLNAETSRALTAEVYFLQCRRDFGLLHLEQTEKECLNQLARVTHMAASNL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 ESLQLKAAVDSWNAIVADVRNKIAFLRTQYNEQINKVKQGFALSTLPPVQLPPPPPSPEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESLQLKAAVDSWNAIVADVRNKIAFLRTQYNEQINKVKQGFALSTLPPVQLPPPPPSPEI
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LMQQFLGRPLVKESFFRPILTVPQMPAVCPGVVSATGQPRAPLMTGIAWALPAPVGDAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LMQQFLGRPLVKESFFRPILTVPQMPAVCPGVVSATGQPRAPLMTGIAWALPAPVGDAVP
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 PSAGLRSDPSIMNWERITDRLKTAFPQQTRKELTDFLRKLKDAYGKSLSELTFDEIVCKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSAGLRSDPSIMNWERITDRLKTAFPQQTRKELTDFLRKLKDAYGKSLSELTFDEIVCKI
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 SQFIDPKKSQSQGKSVSNVNCVSPSHSPSQPDAAQPPKPAWRPLTSQGPATWEGASNPDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQFIDPKKSQSQGKSVSNVNCVSPSHSPSQPDAAQPPKPAWRPLTSQGPATWEGASNPDE
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 EEEEEEPCVICHENLSPENLSVLPCAHKFHAQCIRPWLMQQGTCPTCRLHVLLPEEFPGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEEEEEPCVICHENLSPENLSVLPCAHKFHAQCIRPWLMQQGTCPTCRLHVLLPEEFPGH
1150 1160 1170 1180 1190 1200
pF1KA0 PSRQLPKI
::::::::
XP_005 PSRQLPKI
>>XP_005247971 (OMIM: 608672) PREDICTED: E3 ubiquitin-pr (1208 aa)
initn: 8093 init1: 8093 opt: 8093 Z-score: 5200.0 bits: 974.2 E(85289): 0
Smith-Waterman score: 8093; 100.0% identity (100.0% similar) in 1208 aa overlap (1-1208:1-1208)
10 20 30 40 50 60
pF1KA0 MDSLPDEFFVRHPAVEDQRKEETENKLEKSSGQLNKQENDIPTDLVPVNLLLEVKKLLNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDSLPDEFFVRHPAVEDQRKEETENKLEKSSGQLNKQENDIPTDLVPVNLLLEVKKLLNA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 INTLPKGVVPHIKKFLQEDFSFQTMQREVAANSQNGEEIVPALTLRFLITQLEAALRNIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 INTLPKGVVPHIKKFLQEDFSFQTMQREVAANSQNGEEIVPALTLRFLITQLEAALRNIQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 AGNYTAHQINIGYYLTLLFLYGVALTERGKKEDYTEAENKFLVMKMMIQENEICENFMSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGNYTAHQINIGYYLTLLFLYGVALTERGKKEDYTEAENKFLVMKMMIQENEICENFMSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 VYFGRGLLRCAQKRYNGGLLEFHKSLQEIGDKNDHWFDIDPTEDEDLPTTFKDLLNNFIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VYFGRGLLRCAQKRYNGGLLEFHKSLQEIGDKNDHWFDIDPTEDEDLPTTFKDLLNNFIK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 TTESNIMKQTICSYLDCERSCEADILKNTSYKGFFQLMCSKSCCVYFHKICWKKFKNLKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TTESNIMKQTICSYLDCERSCEADILKNTSYKGFFQLMCSKSCCVYFHKICWKKFKNLKY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PGENDQSFSGKKCLKEGCTGDMVRMLQCDVPGIVKILFEVVRKDEYITIENLGASYRKLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGENDQSFSGKKCLKEGCTGDMVRMLQCDVPGIVKILFEVVRKDEYITIENLGASYRKLI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 SLKITDTDIRPKISLKFNTKDEMPIFKLDYNYFYHLLHIIIISGTDIVRQIFDEAMPPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLKITDTDIRPKISLKFNTKDEMPIFKLDYNYFYHLLHIIIISGTDIVRQIFDEAMPPPL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 LKKELLIHKNVLESYYNHLWTNHPLGGSWHLLYPPNKELPQSKQFDLCLLLALIKHLNVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKKELLIHKNVLESYYNHLWTNHPLGGSWHLLYPPNKELPQSKQFDLCLLLALIKHLNVF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 PAPKKGWNMEPPSSDISKSADILRLCKYRDILLSEILMNGLTESQFNSIWKKVSDILLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PAPKKGWNMEPPSSDISKSADILRLCKYRDILLSEILMNGLTESQFNSIWKKVSDILLRL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 GMMQEDIDKVKENPIENISLDYHQLSVYLGIPVPEIIQRMLSCYQQGIALQSITGSQRIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GMMQEDIDKVKENPIENISLDYHQLSVYLGIPVPEIIQRMLSCYQQGIALQSITGSQRIE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 IEELQNEEEELSPPLMEYNINVKSHPEIQFAEINKDGTSIPSESSTESLKDLQEVKSKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEELQNEEEELSPPLMEYNINVKSHPEIQFAEINKDGTSIPSESSTESLKDLQEVKSKQR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 KKKKTKNKKNKDSKEDQVPYVVEKEEQLRKEQANPHSVSRLIKDDASDVQEDSAMEDKFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKKKTKNKKNKDSKEDQVPYVVEKEEQLRKEQANPHSVSRLIKDDASDVQEDSAMEDKFY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 SLDELHILDMIEQGSAGKVTTDYGETEKERLARQRQLYKLHYQCEDFKRQLRTVTFRWQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLDELHILDMIEQGSAGKVTTDYGETEKERLARQRQLYKLHYQCEDFKRQLRTVTFRWQE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 NQMQIKKKDKIIASLNQQVAFGINKVSKLQRQIHAKDNEIKNLKEQLSMKRSQWEMEKHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQMQIKKKDKIIASLNQQVAFGINKVSKLQRQIHAKDNEIKNLKEQLSMKRSQWEMEKHN
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 LESTMKTYVSKLNAETSRALTAEVYFLQCRRDFGLLHLEQTEKECLNQLARVTHMAASNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LESTMKTYVSKLNAETSRALTAEVYFLQCRRDFGLLHLEQTEKECLNQLARVTHMAASNL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 ESLQLKAAVDSWNAIVADVRNKIAFLRTQYNEQINKVKQGFALSTLPPVQLPPPPPSPEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESLQLKAAVDSWNAIVADVRNKIAFLRTQYNEQINKVKQGFALSTLPPVQLPPPPPSPEI
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LMQQFLGRPLVKESFFRPILTVPQMPAVCPGVVSATGQPRAPLMTGIAWALPAPVGDAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LMQQFLGRPLVKESFFRPILTVPQMPAVCPGVVSATGQPRAPLMTGIAWALPAPVGDAVP
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 PSAGLRSDPSIMNWERITDRLKTAFPQQTRKELTDFLRKLKDAYGKSLSELTFDEIVCKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSAGLRSDPSIMNWERITDRLKTAFPQQTRKELTDFLRKLKDAYGKSLSELTFDEIVCKI
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 SQFIDPKKSQSQGKSVSNVNCVSPSHSPSQPDAAQPPKPAWRPLTSQGPATWEGASNPDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQFIDPKKSQSQGKSVSNVNCVSPSHSPSQPDAAQPPKPAWRPLTSQGPATWEGASNPDE
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 EEEEEEPCVICHENLSPENLSVLPCAHKFHAQCIRPWLMQQGTCPTCRLHVLLPEEFPGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEEEEEPCVICHENLSPENLSVLPCAHKFHAQCIRPWLMQQGTCPTCRLHVLLPEEFPGH
1150 1160 1170 1180 1190 1200
pF1KA0 PSRQLPKI
::::::::
XP_005 PSRQLPKI
>>XP_016863029 (OMIM: 608672) PREDICTED: E3 ubiquitin-pr (1208 aa)
initn: 8093 init1: 8093 opt: 8093 Z-score: 5200.0 bits: 974.2 E(85289): 0
Smith-Waterman score: 8093; 100.0% identity (100.0% similar) in 1208 aa overlap (1-1208:1-1208)
10 20 30 40 50 60
pF1KA0 MDSLPDEFFVRHPAVEDQRKEETENKLEKSSGQLNKQENDIPTDLVPVNLLLEVKKLLNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDSLPDEFFVRHPAVEDQRKEETENKLEKSSGQLNKQENDIPTDLVPVNLLLEVKKLLNA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 INTLPKGVVPHIKKFLQEDFSFQTMQREVAANSQNGEEIVPALTLRFLITQLEAALRNIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INTLPKGVVPHIKKFLQEDFSFQTMQREVAANSQNGEEIVPALTLRFLITQLEAALRNIQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 AGNYTAHQINIGYYLTLLFLYGVALTERGKKEDYTEAENKFLVMKMMIQENEICENFMSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGNYTAHQINIGYYLTLLFLYGVALTERGKKEDYTEAENKFLVMKMMIQENEICENFMSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 VYFGRGLLRCAQKRYNGGLLEFHKSLQEIGDKNDHWFDIDPTEDEDLPTTFKDLLNNFIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VYFGRGLLRCAQKRYNGGLLEFHKSLQEIGDKNDHWFDIDPTEDEDLPTTFKDLLNNFIK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 TTESNIMKQTICSYLDCERSCEADILKNTSYKGFFQLMCSKSCCVYFHKICWKKFKNLKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTESNIMKQTICSYLDCERSCEADILKNTSYKGFFQLMCSKSCCVYFHKICWKKFKNLKY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PGENDQSFSGKKCLKEGCTGDMVRMLQCDVPGIVKILFEVVRKDEYITIENLGASYRKLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGENDQSFSGKKCLKEGCTGDMVRMLQCDVPGIVKILFEVVRKDEYITIENLGASYRKLI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 SLKITDTDIRPKISLKFNTKDEMPIFKLDYNYFYHLLHIIIISGTDIVRQIFDEAMPPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLKITDTDIRPKISLKFNTKDEMPIFKLDYNYFYHLLHIIIISGTDIVRQIFDEAMPPPL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 LKKELLIHKNVLESYYNHLWTNHPLGGSWHLLYPPNKELPQSKQFDLCLLLALIKHLNVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKKELLIHKNVLESYYNHLWTNHPLGGSWHLLYPPNKELPQSKQFDLCLLLALIKHLNVF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 PAPKKGWNMEPPSSDISKSADILRLCKYRDILLSEILMNGLTESQFNSIWKKVSDILLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAPKKGWNMEPPSSDISKSADILRLCKYRDILLSEILMNGLTESQFNSIWKKVSDILLRL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 GMMQEDIDKVKENPIENISLDYHQLSVYLGIPVPEIIQRMLSCYQQGIALQSITGSQRIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GMMQEDIDKVKENPIENISLDYHQLSVYLGIPVPEIIQRMLSCYQQGIALQSITGSQRIE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 IEELQNEEEELSPPLMEYNINVKSHPEIQFAEINKDGTSIPSESSTESLKDLQEVKSKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEELQNEEEELSPPLMEYNINVKSHPEIQFAEINKDGTSIPSESSTESLKDLQEVKSKQR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 KKKKTKNKKNKDSKEDQVPYVVEKEEQLRKEQANPHSVSRLIKDDASDVQEDSAMEDKFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKKKTKNKKNKDSKEDQVPYVVEKEEQLRKEQANPHSVSRLIKDDASDVQEDSAMEDKFY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 SLDELHILDMIEQGSAGKVTTDYGETEKERLARQRQLYKLHYQCEDFKRQLRTVTFRWQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLDELHILDMIEQGSAGKVTTDYGETEKERLARQRQLYKLHYQCEDFKRQLRTVTFRWQE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 NQMQIKKKDKIIASLNQQVAFGINKVSKLQRQIHAKDNEIKNLKEQLSMKRSQWEMEKHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQMQIKKKDKIIASLNQQVAFGINKVSKLQRQIHAKDNEIKNLKEQLSMKRSQWEMEKHN
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 LESTMKTYVSKLNAETSRALTAEVYFLQCRRDFGLLHLEQTEKECLNQLARVTHMAASNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LESTMKTYVSKLNAETSRALTAEVYFLQCRRDFGLLHLEQTEKECLNQLARVTHMAASNL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 ESLQLKAAVDSWNAIVADVRNKIAFLRTQYNEQINKVKQGFALSTLPPVQLPPPPPSPEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESLQLKAAVDSWNAIVADVRNKIAFLRTQYNEQINKVKQGFALSTLPPVQLPPPPPSPEI
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LMQQFLGRPLVKESFFRPILTVPQMPAVCPGVVSATGQPRAPLMTGIAWALPAPVGDAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMQQFLGRPLVKESFFRPILTVPQMPAVCPGVVSATGQPRAPLMTGIAWALPAPVGDAVP
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 PSAGLRSDPSIMNWERITDRLKTAFPQQTRKELTDFLRKLKDAYGKSLSELTFDEIVCKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSAGLRSDPSIMNWERITDRLKTAFPQQTRKELTDFLRKLKDAYGKSLSELTFDEIVCKI
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 SQFIDPKKSQSQGKSVSNVNCVSPSHSPSQPDAAQPPKPAWRPLTSQGPATWEGASNPDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQFIDPKKSQSQGKSVSNVNCVSPSHSPSQPDAAQPPKPAWRPLTSQGPATWEGASNPDE
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 EEEEEEPCVICHENLSPENLSVLPCAHKFHAQCIRPWLMQQGTCPTCRLHVLLPEEFPGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEEEEPCVICHENLSPENLSVLPCAHKFHAQCIRPWLMQQGTCPTCRLHVLLPEEFPGH
1150 1160 1170 1180 1190 1200
pF1KA0 PSRQLPKI
::::::::
XP_016 PSRQLPKI
>>XP_005247973 (OMIM: 608672) PREDICTED: E3 ubiquitin-pr (1208 aa)
initn: 8093 init1: 8093 opt: 8093 Z-score: 5200.0 bits: 974.2 E(85289): 0
Smith-Waterman score: 8093; 100.0% identity (100.0% similar) in 1208 aa overlap (1-1208:1-1208)
10 20 30 40 50 60
pF1KA0 MDSLPDEFFVRHPAVEDQRKEETENKLEKSSGQLNKQENDIPTDLVPVNLLLEVKKLLNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDSLPDEFFVRHPAVEDQRKEETENKLEKSSGQLNKQENDIPTDLVPVNLLLEVKKLLNA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 INTLPKGVVPHIKKFLQEDFSFQTMQREVAANSQNGEEIVPALTLRFLITQLEAALRNIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 INTLPKGVVPHIKKFLQEDFSFQTMQREVAANSQNGEEIVPALTLRFLITQLEAALRNIQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 AGNYTAHQINIGYYLTLLFLYGVALTERGKKEDYTEAENKFLVMKMMIQENEICENFMSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGNYTAHQINIGYYLTLLFLYGVALTERGKKEDYTEAENKFLVMKMMIQENEICENFMSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 VYFGRGLLRCAQKRYNGGLLEFHKSLQEIGDKNDHWFDIDPTEDEDLPTTFKDLLNNFIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VYFGRGLLRCAQKRYNGGLLEFHKSLQEIGDKNDHWFDIDPTEDEDLPTTFKDLLNNFIK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 TTESNIMKQTICSYLDCERSCEADILKNTSYKGFFQLMCSKSCCVYFHKICWKKFKNLKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TTESNIMKQTICSYLDCERSCEADILKNTSYKGFFQLMCSKSCCVYFHKICWKKFKNLKY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PGENDQSFSGKKCLKEGCTGDMVRMLQCDVPGIVKILFEVVRKDEYITIENLGASYRKLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGENDQSFSGKKCLKEGCTGDMVRMLQCDVPGIVKILFEVVRKDEYITIENLGASYRKLI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 SLKITDTDIRPKISLKFNTKDEMPIFKLDYNYFYHLLHIIIISGTDIVRQIFDEAMPPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLKITDTDIRPKISLKFNTKDEMPIFKLDYNYFYHLLHIIIISGTDIVRQIFDEAMPPPL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 LKKELLIHKNVLESYYNHLWTNHPLGGSWHLLYPPNKELPQSKQFDLCLLLALIKHLNVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKKELLIHKNVLESYYNHLWTNHPLGGSWHLLYPPNKELPQSKQFDLCLLLALIKHLNVF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 PAPKKGWNMEPPSSDISKSADILRLCKYRDILLSEILMNGLTESQFNSIWKKVSDILLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PAPKKGWNMEPPSSDISKSADILRLCKYRDILLSEILMNGLTESQFNSIWKKVSDILLRL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 GMMQEDIDKVKENPIENISLDYHQLSVYLGIPVPEIIQRMLSCYQQGIALQSITGSQRIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GMMQEDIDKVKENPIENISLDYHQLSVYLGIPVPEIIQRMLSCYQQGIALQSITGSQRIE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 IEELQNEEEELSPPLMEYNINVKSHPEIQFAEINKDGTSIPSESSTESLKDLQEVKSKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEELQNEEEELSPPLMEYNINVKSHPEIQFAEINKDGTSIPSESSTESLKDLQEVKSKQR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 KKKKTKNKKNKDSKEDQVPYVVEKEEQLRKEQANPHSVSRLIKDDASDVQEDSAMEDKFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKKKTKNKKNKDSKEDQVPYVVEKEEQLRKEQANPHSVSRLIKDDASDVQEDSAMEDKFY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 SLDELHILDMIEQGSAGKVTTDYGETEKERLARQRQLYKLHYQCEDFKRQLRTVTFRWQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLDELHILDMIEQGSAGKVTTDYGETEKERLARQRQLYKLHYQCEDFKRQLRTVTFRWQE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 NQMQIKKKDKIIASLNQQVAFGINKVSKLQRQIHAKDNEIKNLKEQLSMKRSQWEMEKHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQMQIKKKDKIIASLNQQVAFGINKVSKLQRQIHAKDNEIKNLKEQLSMKRSQWEMEKHN
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 LESTMKTYVSKLNAETSRALTAEVYFLQCRRDFGLLHLEQTEKECLNQLARVTHMAASNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LESTMKTYVSKLNAETSRALTAEVYFLQCRRDFGLLHLEQTEKECLNQLARVTHMAASNL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 ESLQLKAAVDSWNAIVADVRNKIAFLRTQYNEQINKVKQGFALSTLPPVQLPPPPPSPEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESLQLKAAVDSWNAIVADVRNKIAFLRTQYNEQINKVKQGFALSTLPPVQLPPPPPSPEI
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LMQQFLGRPLVKESFFRPILTVPQMPAVCPGVVSATGQPRAPLMTGIAWALPAPVGDAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LMQQFLGRPLVKESFFRPILTVPQMPAVCPGVVSATGQPRAPLMTGIAWALPAPVGDAVP
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 PSAGLRSDPSIMNWERITDRLKTAFPQQTRKELTDFLRKLKDAYGKSLSELTFDEIVCKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSAGLRSDPSIMNWERITDRLKTAFPQQTRKELTDFLRKLKDAYGKSLSELTFDEIVCKI
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 SQFIDPKKSQSQGKSVSNVNCVSPSHSPSQPDAAQPPKPAWRPLTSQGPATWEGASNPDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQFIDPKKSQSQGKSVSNVNCVSPSHSPSQPDAAQPPKPAWRPLTSQGPATWEGASNPDE
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 EEEEEEPCVICHENLSPENLSVLPCAHKFHAQCIRPWLMQQGTCPTCRLHVLLPEEFPGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEEEEEPCVICHENLSPENLSVLPCAHKFHAQCIRPWLMQQGTCPTCRLHVLLPEEFPGH
1150 1160 1170 1180 1190 1200
pF1KA0 PSRQLPKI
::::::::
XP_005 PSRQLPKI
>>XP_005247976 (OMIM: 608672) PREDICTED: E3 ubiquitin-pr (1002 aa)
initn: 4162 init1: 4162 opt: 4182 Z-score: 2693.9 bits: 510.2 E(85289): 2.6e-143
Smith-Waterman score: 6266; 82.9% identity (82.9% similar) in 1208 aa overlap (1-1208:1-1002)
10 20 30 40 50 60
pF1KA0 MDSLPDEFFVRHPAVEDQRKEETENKLEKSSGQLNKQENDIPTDLVPVNLLLEVKKLLNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDSLPDEFFVRHPAVEDQRKEETENKLEKSSGQLNKQENDIPTDLVPVNLLLEVKKLLNA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 INTLPKGVVPHIKKFLQEDFSFQTMQREVAANSQNGEEIVPALTLRFLITQLEAALRNIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 INTLPKGVVPHIKKFLQEDFSFQTMQREVAANSQNGEEIVPALTLRFLITQLEAALRNIQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 AGNYTAHQINIGYYLTLLFLYGVALTERGKKEDYTEAENKFLVMKMMIQENEICENFMSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGNYTAHQINIGYYLTLLFLYGVALTERGKKEDYTEAENKFLVMKMMIQENEICENFMSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 VYFGRGLLRCAQKRYNGGLLEFHKSLQEIGDKNDHWFDIDPTEDEDLPTTFKDLLNNFIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VYFGRGLLRCAQKRYNGGLLEFHKSLQEIGDKNDHWFDIDPTEDEDLPTTFKDLLNNFIK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 TTESNIMKQTICSYLDCERSCEADILKNTSYKGFFQLMCSKSCCVYFHKICWKKFKNLKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TTESNIMKQTICSYLDCERSCEADILKNTSYKGFFQLMCSKSCCVYFHKICWKKFKNLKY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PGENDQSFSGKKCLKEGCTGDMVRMLQCDVPGIVKILFEVVRKDEYITIENLGASYRKLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGENDQSFSGKKCLKEGCTGDMVRMLQCDVPGIVKILFEVVRKDEYITIENLGASYRKLI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 SLKITDTDIRPKISLKFNTKDEMPIFKLDYNYFYHLLHIIIISGTDIVRQIFDEAMPPPL
::::::::::::::::::::
XP_005 SLKITDTDIRPKISLKFNTK----------------------------------------
370 380
430 440 450 460 470 480
pF1KA0 LKKELLIHKNVLESYYNHLWTNHPLGGSWHLLYPPNKELPQSKQFDLCLLLALIKHLNVF
XP_005 ------------------------------------------------------------
490 500 510 520 530 540
pF1KA0 PAPKKGWNMEPPSSDISKSADILRLCKYRDILLSEILMNGLTESQFNSIWKKVSDILLRL
XP_005 ------------------------------------------------------------
550 560 570 580 590 600
pF1KA0 GMMQEDIDKVKENPIENISLDYHQLSVYLGIPVPEIIQRMLSCYQQGIALQSITGSQRIE
::::::::::::::
XP_005 ----------------------------------------------GIALQSITGSQRIE
390
610 620 630 640 650 660
pF1KA0 IEELQNEEEELSPPLMEYNINVKSHPEIQFAEINKDGTSIPSESSTESLKDLQEVKSKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEELQNEEEELSPPLMEYNINVKSHPEIQFAEINKDGTSIPSESSTESLKDLQEVKSKQR
400 410 420 430 440 450
670 680 690 700 710 720
pF1KA0 KKKKTKNKKNKDSKEDQVPYVVEKEEQLRKEQANPHSVSRLIKDDASDVQEDSAMEDKFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKKKTKNKKNKDSKEDQVPYVVEKEEQLRKEQANPHSVSRLIKDDASDVQEDSAMEDKFY
460 470 480 490 500 510
730 740 750 760 770 780
pF1KA0 SLDELHILDMIEQGSAGKVTTDYGETEKERLARQRQLYKLHYQCEDFKRQLRTVTFRWQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLDELHILDMIEQGSAGKVTTDYGETEKERLARQRQLYKLHYQCEDFKRQLRTVTFRWQE
520 530 540 550 560 570
790 800 810 820 830 840
pF1KA0 NQMQIKKKDKIIASLNQQVAFGINKVSKLQRQIHAKDNEIKNLKEQLSMKRSQWEMEKHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQMQIKKKDKIIASLNQQVAFGINKVSKLQRQIHAKDNEIKNLKEQLSMKRSQWEMEKHN
580 590 600 610 620 630
850 860 870 880 890 900
pF1KA0 LESTMKTYVSKLNAETSRALTAEVYFLQCRRDFGLLHLEQTEKECLNQLARVTHMAASNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LESTMKTYVSKLNAETSRALTAEVYFLQCRRDFGLLHLEQTEKECLNQLARVTHMAASNL
640 650 660 670 680 690
910 920 930 940 950 960
pF1KA0 ESLQLKAAVDSWNAIVADVRNKIAFLRTQYNEQINKVKQGFALSTLPPVQLPPPPPSPEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESLQLKAAVDSWNAIVADVRNKIAFLRTQYNEQINKVKQGFALSTLPPVQLPPPPPSPEI
700 710 720 730 740 750
970 980 990 1000 1010 1020
pF1KA0 LMQQFLGRPLVKESFFRPILTVPQMPAVCPGVVSATGQPRAPLMTGIAWALPAPVGDAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LMQQFLGRPLVKESFFRPILTVPQMPAVCPGVVSATGQPRAPLMTGIAWALPAPVGDAVP
760 770 780 790 800 810
1030 1040 1050 1060 1070 1080
pF1KA0 PSAGLRSDPSIMNWERITDRLKTAFPQQTRKELTDFLRKLKDAYGKSLSELTFDEIVCKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSAGLRSDPSIMNWERITDRLKTAFPQQTRKELTDFLRKLKDAYGKSLSELTFDEIVCKI
820 830 840 850 860 870
1090 1100 1110 1120 1130 1140
pF1KA0 SQFIDPKKSQSQGKSVSNVNCVSPSHSPSQPDAAQPPKPAWRPLTSQGPATWEGASNPDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQFIDPKKSQSQGKSVSNVNCVSPSHSPSQPDAAQPPKPAWRPLTSQGPATWEGASNPDE
880 890 900 910 920 930
1150 1160 1170 1180 1190 1200
pF1KA0 EEEEEEPCVICHENLSPENLSVLPCAHKFHAQCIRPWLMQQGTCPTCRLHVLLPEEFPGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEEEEEPCVICHENLSPENLSVLPCAHKFHAQCIRPWLMQQGTCPTCRLHVLLPEEFPGH
940 950 960 970 980 990
pF1KA0 PSRQLPKI
::::::::
XP_005 PSRQLPKI
1000
>>NP_001317611 (OMIM: 602259) E3 ubiquitin-protein ligas (1715 aa)
initn: 557 init1: 183 opt: 333 Z-score: 223.6 bits: 53.9 E(85289): 1e-05
Smith-Waterman score: 485; 25.0% identity (55.0% similar) in 651 aa overlap (621-1206:1084-1710)
600 610 620 630 640
pF1KA0 QSITGSQRIEIEELQNEEEELSPPLMEYNINVKSHP---EIQFAEINKDGTSIPSESSTE
:: .: : :. : .. : :. :. ::
NP_001 SVPVVPSFVANDRADKNAAAYFEGHHLNAENVAGHQIASETQILE-GSLGISVKSHCST-
1060 1070 1080 1090 1100 1110
650 660 670 680 690 700
pF1KA0 SLKDLQEVKSKQRKKKKTKNKKNKDSKEDQVPYVVEKEEQLRKEQANPHSVSRLIKDDAS
: . : :. .... .. :...: . .: . .. . : .:: : .
NP_001 --GDAHTVLSE--SNRNDEHCGNSNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEV
1120 1130 1140 1150 1160
710 720 730 740 750 760
pF1KA0 DVQEDSAMEDKFYSLDELHILDMIEQGSAGKVTTDYGETEKERLARQRQLY-KLHYQCED
... . .:.. ..... .. : . .: .: . . . : . :.: ::. . :.
NP_001 NTEPYNPFEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEE
1170 1180 1190 1200 1210 1220
770 780 790 800 810
pF1KA0 ----------FKRQLRTVTFRWQENQMQIKKKDKIIASLNQQVAFGINKVSKLQRQIHAK
: ..:. .::... .:... : ::... :.:::. .....
NP_001 NKISKTELDWFLQDLEREIKKWQQEKKEIQERLK---SLKKK----IKKVSN-ASEMYTQ
1230 1240 1250 1260 1270
820 830 840 850 860 870
pF1KA0 DNEIKNLKEQLSMKRS-----QWEMEKHNLESTMKTYVSKLNAETSRALTAEVYFLQCRR
:. :. ...: . .: :: ..: .: . .::..::: :. .
NP_001 KNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWK
1280 1290 1300 1310 1320 1330
880 890 900 910 920 930
pF1KA0 DFGLLHLEQTEKECLNQLARVTHMAASNLESLQLKAAVDSWNAIVADVRNKIAFLRTQYN
. . .:. :.. : .. .. . .... . ::. ....: ..: ..:..
NP_001 ESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFE
1340 1350 1360 1370 1380 1390
940 950 960 970
pF1KA0 EQINKVKQGFALSTLPPVQLPPPP-PS-----PEILMQQFL--GRPLV---------KES
:::. .:.: :: : ::. :. ::.: .. :. :: . .
NP_001 EQIKAIKNGSRLSELSKVQISELSFPACNTVHPELLPESSGDDGQGLVTSASDVTGNHAA
1400 1410 1420 1430 1440 1450
980 990 1000 1010 1020
pF1KA0 FFR-P-ILTVPQMPAVCPGVV---SATGQPRAPLMTGIAWALPA------PVGD---AVP
. : : .... . :. :... :::.: .:: : : ::.: ::
NP_001 LHRDPSVFSAGDSPGEAPSALLPGPPPGQPEATQLTGPKRAGQAALSERSPVADRKQPVP
1460 1470 1480 1490 1500 1510
1030 1040 1050 1060 1070
pF1KA0 PSAGLRSDPSIMN-WERITDRLKTAFPQQTRKELTDFLRKLKDAYGKSLSELTFDEIVCK
:. . ::. : . .. : ..:...:: . ::. :..:... .::: :..:::: .
NP_001 PGRAARSSQSPKKPFNSIIEHLSVVFPCYNSTELAGFIKKVRSKNKNSLSGLSIDEIVQR
1520 1530 1540 1550 1560 1570
1080 1090 1100 1110 1120 1130
pF1KA0 ISQFI---DPKKSQSQGKSVSNV--NCVSPSHSPSQ--PDAAQPPKPAWRPLTSQG-PAT
... : . ::. . ::. . . ..: :: :... :.: . .. :.
NP_001 VTEHILDEQKKKKPNPGKDKRTYEPSSATPVTRSSQGSPSVVVAPSPKTKGQKAEDVPVR
1580 1590 1600 1610 1620 1630
1140 1150 1160 1170 1180 1190
pF1KA0 WE-GASNPDEEEEEEEPCVICHENLSPENLSVLPCAHKFHAQCIRPWLMQQGTCPTCRLH
:::. : :::: .. .:. :: :.::.: :.. :: :..::.:. .
NP_001 IALGASS----------CEICHEVFKSKNVRVLKCGHKYHKGCFKQWLKGQSACPACQGR
1640 1650 1660 1670 1680
1200
pF1KA0 VLLPEEFP---GHPSR--QLPKI
:: :: : : ::. .::
NP_001 DLLTEESPSGRGWPSQNQELPSCSSR
1690 1700 1710
>--
initn: 210 init1: 171 opt: 296 Z-score: 199.9 bits: 49.5 E(85289): 0.00022
Smith-Waterman score: 296; 27.3% identity (54.6% similar) in 260 aa overlap (128-380:217-472)
100 110 120 130 140 150
pF1KA0 EIVPALTLRFLITQLEAALRNIQAGNYTAHQINIGYYLTLLFLYGVALTERG--KKEDYT
:.:... .: .::.:.. : . :. .
NP_001 GYMALLEQRCRSAAQAFTELLNGLDPQKIKQLNLAMINYVLVVYGLAISLLGIGQPEELS
190 200 210 220 230 240
160 170 180 190 200 210
pF1KA0 EAENKFLVMKMMIQENEICENFMSLVYFGRGLLRCAQKRYNGGLLEFHKSLQEIGDKND-
::::.: : .: :. :.. :.: : : . ..:. .: .:.:. :
NP_001 EAENQF---KRII-EHYPSEGLDCLAYCGIGKVYLKKNRFLEALNHFEKARTLIYRLPGV
250 260 270 280 290 300
220 230 240 250 260 270
pF1KA0 -HWFDIDPTEDEDLPTTFKDLLNNFIKTTESNIMKQTICSYLDCERSCEADI-LKNTSYK
: . .:. : .: ::..:.. . . ..:: : :. . .: . . ..:
NP_001 LTWPTSNVIIEESQPQKIKMLLEKFVEECKFPPVPDAICCYQKCHGYSKIQIYITDPDFK
310 320 330 340 350 360
280 290 300 310 320 330
pF1KA0 GFFQLMCSKSCCVYFHKICWKKFKNLKYPGENDQSFSGKKCLKEGCTGDMVRMLQCDVPG
::... : . : . :: ::::.:. . . :..: :: : : . ... . :
NP_001 GFIRISCCQYCKIEFHMNCWKKLKTTTFNDKIDKDFLQGICLTPDCEGVISKIIIFSSGG
370 380 390 400 410 420
340 350 360 370 380 390
pF1KA0 IVKILFE-VVRKDEYITIENLGASYRKLISLKIT-DTDIRPKISLKFNTKDEMPIFKLDY
:: :: : :.. : . .: .:.. : .. ::. : :
NP_001 EVKCEFEHKVIKEKVPPRPILKQKCSSLEKLRLKEDKKLKRKIQKKEAKKLAQERMEEDL
430 440 450 460 470 480
400 410 420 430 440 450
pF1KA0 NYFYHLLHIIIISGTDIVRQIFDEAMPPPLLKKELLIHKNVLESYYNHLWTNHPLGGSWH
NP_001 RESNPPKNEEQKETVDNVQRCQFLDDRILQCIKQYADKIKSGIQNTAMLLKELLSWKVLS
490 500 510 520 530 540
>>NP_001317610 (OMIM: 602259) E3 ubiquitin-protein ligas (1715 aa)
initn: 557 init1: 183 opt: 333 Z-score: 223.6 bits: 53.9 E(85289): 1e-05
Smith-Waterman score: 485; 25.0% identity (55.0% similar) in 651 aa overlap (621-1206:1084-1710)
600 610 620 630 640
pF1KA0 QSITGSQRIEIEELQNEEEELSPPLMEYNINVKSHP---EIQFAEINKDGTSIPSESSTE
:: .: : :. : .. : :. :. ::
NP_001 SVPVVPSFVANDRADKNAAAYFEGHHLNAENVAGHQIASETQILE-GSLGISVKSHCST-
1060 1070 1080 1090 1100 1110
650 660 670 680 690 700
pF1KA0 SLKDLQEVKSKQRKKKKTKNKKNKDSKEDQVPYVVEKEEQLRKEQANPHSVSRLIKDDAS
: . : :. .... .. :...: . .: . .. . : .:: : .
NP_001 --GDAHTVLSE--SNRNDEHCGNSNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEV
1120 1130 1140 1150 1160
710 720 730 740 750 760
pF1KA0 DVQEDSAMEDKFYSLDELHILDMIEQGSAGKVTTDYGETEKERLARQRQLY-KLHYQCED
... . .:.. ..... .. : . .: .: . . . : . :.: ::. . :.
NP_001 NTEPYNPFEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEE
1170 1180 1190 1200 1210 1220
770 780 790 800 810
pF1KA0 ----------FKRQLRTVTFRWQENQMQIKKKDKIIASLNQQVAFGINKVSKLQRQIHAK
: ..:. .::... .:... : ::... :.:::. .....
NP_001 NKISKTELDWFLQDLEREIKKWQQEKKEIQERLK---SLKKK----IKKVSN-ASEMYTQ
1230 1240 1250 1260 1270
820 830 840 850 860 870
pF1KA0 DNEIKNLKEQLSMKRS-----QWEMEKHNLESTMKTYVSKLNAETSRALTAEVYFLQCRR
:. :. ...: . .: :: ..: .: . .::..::: :. .
NP_001 KNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWK
1280 1290 1300 1310 1320 1330
880 890 900 910 920 930
pF1KA0 DFGLLHLEQTEKECLNQLARVTHMAASNLESLQLKAAVDSWNAIVADVRNKIAFLRTQYN
. . .:. :.. : .. .. . .... . ::. ....: ..: ..:..
NP_001 ESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFE
1340 1350 1360 1370 1380 1390
940 950 960 970
pF1KA0 EQINKVKQGFALSTLPPVQLPPPP-PS-----PEILMQQFL--GRPLV---------KES
:::. .:.: :: : ::. :. ::.: .. :. :: . .
NP_001 EQIKAIKNGSRLSELSKVQISELSFPACNTVHPELLPESSGDDGQGLVTSASDVTGNHAA
1400 1410 1420 1430 1440 1450
980 990 1000 1010 1020
pF1KA0 FFR-P-ILTVPQMPAVCPGVV---SATGQPRAPLMTGIAWALPA------PVGD---AVP
. : : .... . :. :... :::.: .:: : : ::.: ::
NP_001 LHRDPSVFSAGDSPGEAPSALLPGPPPGQPEATQLTGPKRAGQAALSERSPVADRKQPVP
1460 1470 1480 1490 1500 1510
1030 1040 1050 1060 1070
pF1KA0 PSAGLRSDPSIMN-WERITDRLKTAFPQQTRKELTDFLRKLKDAYGKSLSELTFDEIVCK
:. . ::. : . .. : ..:...:: . ::. :..:... .::: :..:::: .
NP_001 PGRAARSSQSPKKPFNSIIEHLSVVFPCYNSTELAGFIKKVRSKNKNSLSGLSIDEIVQR
1520 1530 1540 1550 1560 1570
1080 1090 1100 1110 1120 1130
pF1KA0 ISQFI---DPKKSQSQGKSVSNV--NCVSPSHSPSQ--PDAAQPPKPAWRPLTSQG-PAT
... : . ::. . ::. . . ..: :: :... :.: . .. :.
NP_001 VTEHILDEQKKKKPNPGKDKRTYEPSSATPVTRSSQGSPSVVVAPSPKTKGQKAEDVPVR
1580 1590 1600 1610 1620 1630
1140 1150 1160 1170 1180 1190
pF1KA0 WE-GASNPDEEEEEEEPCVICHENLSPENLSVLPCAHKFHAQCIRPWLMQQGTCPTCRLH
:::. : :::: .. .:. :: :.::.: :.. :: :..::.:. .
NP_001 IALGASS----------CEICHEVFKSKNVRVLKCGHKYHKGCFKQWLKGQSACPACQGR
1640 1650 1660 1670 1680
1200
pF1KA0 VLLPEEFP---GHPSR--QLPKI
:: :: : : ::. .::
NP_001 DLLTEESPSGRGWPSQNQELPSCSSR
1690 1700 1710
>--
initn: 210 init1: 171 opt: 296 Z-score: 199.9 bits: 49.5 E(85289): 0.00022
Smith-Waterman score: 296; 27.3% identity (54.6% similar) in 260 aa overlap (128-380:217-472)
100 110 120 130 140 150
pF1KA0 EIVPALTLRFLITQLEAALRNIQAGNYTAHQINIGYYLTLLFLYGVALTERG--KKEDYT
:.:... .: .::.:.. : . :. .
NP_001 GYMALLEQRCRSAAQAFTELLNGLDPQKIKQLNLAMINYVLVVYGLAISLLGIGQPEELS
190 200 210 220 230 240
160 170 180 190 200 210
pF1KA0 EAENKFLVMKMMIQENEICENFMSLVYFGRGLLRCAQKRYNGGLLEFHKSLQEIGDKND-
::::.: : .: :. :.. :.: : : . ..:. .: .:.:. :
NP_001 EAENQF---KRII-EHYPSEGLDCLAYCGIGKVYLKKNRFLEALNHFEKARTLIYRLPGV
250 260 270 280 290 300
220 230 240 250 260 270
pF1KA0 -HWFDIDPTEDEDLPTTFKDLLNNFIKTTESNIMKQTICSYLDCERSCEADI-LKNTSYK
: . .:. : .: ::..:.. . . ..:: : :. . .: . . ..:
NP_001 LTWPTSNVIIEESQPQKIKMLLEKFVEECKFPPVPDAICCYQKCHGYSKIQIYITDPDFK
310 320 330 340 350 360
280 290 300 310 320 330
pF1KA0 GFFQLMCSKSCCVYFHKICWKKFKNLKYPGENDQSFSGKKCLKEGCTGDMVRMLQCDVPG
::... : . : . :: ::::.:. . . :..: :: : : . ... . :
NP_001 GFIRISCCQYCKIEFHMNCWKKLKTTTFNDKIDKDFLQGICLTPDCEGVISKIIIFSSGG
370 380 390 400 410 420
340 350 360 370 380 390
pF1KA0 IVKILFE-VVRKDEYITIENLGASYRKLISLKIT-DTDIRPKISLKFNTKDEMPIFKLDY
:: :: : :.. : . .: .:.. : .. ::. : :
NP_001 EVKCEFEHKVIKEKVPPRPILKQKCSSLEKLRLKEDKKLKRKIQKKEAKKLAQERMEEDL
430 440 450 460 470 480
400 410 420 430 440 450
pF1KA0 NYFYHLLHIIIISGTDIVRQIFDEAMPPPLLKKELLIHKNVLESYYNHLWTNHPLGGSWH
NP_001 RESNPPKNEEQKETVDNVQRCQFLDDRILQCIKQYADKIKSGIQNTAMLLKELLSWKVLS
490 500 510 520 530 540
1208 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 00:55:34 2016 done: Fri Nov 4 00:55:37 2016
Total Scan time: 16.270 Total Display time: 0.570
Function used was FASTA [36.3.4 Apr, 2011]