Result of FASTA (omim) for
pF1KA0619
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0619, 1388 aa
1>>>pF1KA0619 1388 - 1388 aa - 1388 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 21.0215+/-0.000682; mu= -53.8955+/- 0.042
mean_var=1189.4978+/-249.658, 0's: 0 Z-trim(118.1): 1392 B-trim: 0 in 0/58
Lambda= 0.037187
statistics sampled from 29131 (30679) to 29131 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.663), E-opt: 0.2 (0.36), width: 16
Scan time: 19.250
The best scores are: opt bits E(85289)
NP_004841 (OMIM: 604002) rho-associated protein ki (1388) 9053 503.6 4.1e-141
XP_016860867 (OMIM: 604002) PREDICTED: rho-associa (1404) 9048 503.3 5e-141
XP_005246247 (OMIM: 604002) PREDICTED: rho-associa (1417) 9048 503.3 5e-141
NP_001308572 (OMIM: 604002) rho-associated protein (1302) 8483 473.0 6.3e-132
XP_016860868 (OMIM: 604002) PREDICTED: rho-associa (1331) 8478 472.7 7.7e-132
XP_011508719 (OMIM: 604002) PREDICTED: rho-associa (1331) 8478 472.7 7.7e-132
NP_005397 (OMIM: 601702) rho-associated protein ki (1354) 4176 241.9 2.3e-62
XP_011524439 (OMIM: 601702) PREDICTED: rho-associa ( 891) 1918 120.7 5e-26
XP_011542610 (OMIM: 603412) PREDICTED: serine/thre (1783) 1570 102.2 3.6e-20
XP_011542608 (OMIM: 603412) PREDICTED: serine/thre (1845) 1570 102.2 3.7e-20
XP_016858071 (OMIM: 603412) PREDICTED: serine/thre (1589) 1516 99.3 2.4e-19
NP_003598 (OMIM: 603412) serine/threonine-protein (1719) 1516 99.3 2.6e-19
XP_005273381 (OMIM: 603412) PREDICTED: serine/thre (1732) 1516 99.3 2.6e-19
XP_005273379 (OMIM: 603412) PREDICTED: serine/thre (1754) 1516 99.3 2.6e-19
XP_016858067 (OMIM: 603412) PREDICTED: serine/thre (1767) 1516 99.3 2.6e-19
XP_005273378 (OMIM: 603412) PREDICTED: serine/thre (1781) 1516 99.3 2.6e-19
XP_005273377 (OMIM: 603412) PREDICTED: serine/thre (1794) 1516 99.3 2.7e-19
XP_006711898 (OMIM: 603412) PREDICTED: serine/thre (1797) 1516 99.3 2.7e-19
XP_011542609 (OMIM: 603412) PREDICTED: serine/thre (1810) 1516 99.3 2.7e-19
XP_006711897 (OMIM: 603412) PREDICTED: serine/thre (1816) 1516 99.3 2.7e-19
XP_005273375 (OMIM: 603412) PREDICTED: serine/thre (1829) 1516 99.3 2.7e-19
XP_005273374 (OMIM: 603412) PREDICTED: serine/thre (1832) 1516 99.3 2.7e-19
XP_011535689 (OMIM: 614062) PREDICTED: serine/thre (1460) 1486 97.7 6.9e-19
XP_005268287 (OMIM: 614062) PREDICTED: serine/thre (1490) 1486 97.7 7e-19
XP_005268286 (OMIM: 614062) PREDICTED: serine/thre (1685) 1486 97.7 7.7e-19
XP_005268285 (OMIM: 614062) PREDICTED: serine/thre (1702) 1486 97.7 7.8e-19
NP_006026 (OMIM: 614062) serine/threonine-protein (1711) 1486 97.7 7.8e-19
XP_005268284 (OMIM: 614062) PREDICTED: serine/thre (1728) 1486 97.7 7.9e-19
XP_011542611 (OMIM: 603412) PREDICTED: serine/thre (1764) 1479 97.3 1e-18
NP_055641 (OMIM: 603412) serine/threonine-protein (1638) 1476 97.2 1.1e-18
XP_011543458 (OMIM: 613991) PREDICTED: serine/thre (1562) 1429 94.6 6.1e-18
XP_016873487 (OMIM: 613991) PREDICTED: serine/thre (1081) 1398 92.8 1.4e-17
XP_011543463 (OMIM: 613991) PREDICTED: serine/thre (1135) 1398 92.9 1.5e-17
XP_011536090 (OMIM: 605629,617090) PREDICTED: citr (2011) 1410 93.7 1.5e-17
XP_011536089 (OMIM: 605629,617090) PREDICTED: citr (2012) 1410 93.7 1.5e-17
XP_016873486 (OMIM: 613991) PREDICTED: serine/thre (1139) 1398 92.9 1.5e-17
NP_009105 (OMIM: 605629,617090) citron Rho-interac (2027) 1410 93.7 1.5e-17
XP_011543461 (OMIM: 613991) PREDICTED: serine/thre (1481) 1398 92.9 1.8e-17
XP_011543460 (OMIM: 613991) PREDICTED: serine/thre (1495) 1398 92.9 1.9e-17
XP_011543459 (OMIM: 613991) PREDICTED: serine/thre (1530) 1398 92.9 1.9e-17
NP_059995 (OMIM: 613991) serine/threonine-protein (1551) 1398 93.0 1.9e-17
XP_016873485 (OMIM: 613991) PREDICTED: serine/thre (1568) 1398 93.0 1.9e-17
XP_011543457 (OMIM: 613991) PREDICTED: serine/thre (1569) 1398 93.0 1.9e-17
XP_016874226 (OMIM: 605629,617090) PREDICTED: citr (2053) 1396 92.9 2.6e-17
XP_006719269 (OMIM: 605629,617090) PREDICTED: citr (2054) 1396 92.9 2.6e-17
XP_016874225 (OMIM: 605629,617090) PREDICTED: citr (2068) 1396 92.9 2.6e-17
XP_016874224 (OMIM: 605629,617090) PREDICTED: citr (2068) 1396 92.9 2.6e-17
NP_001193928 (OMIM: 605629,617090) citron Rho-inte (2069) 1396 92.9 2.6e-17
XP_011536087 (OMIM: 605629,617090) PREDICTED: citr (2069) 1396 92.9 2.6e-17
XP_011536086 (OMIM: 605629,617090) PREDICTED: citr (2083) 1396 92.9 2.6e-17
>>NP_004841 (OMIM: 604002) rho-associated protein kinase (1388 aa)
initn: 9053 init1: 9053 opt: 9053 Z-score: 2654.4 bits: 503.6 E(85289): 4.1e-141
Smith-Waterman score: 9053; 99.9% identity (100.0% similar) in 1388 aa overlap (1-1388:1-1388)
10 20 30 40 50 60
pF1KA0 MSRPPPTGKMPGAPETAPGDGAGASRQRKLEALIRDPRSPINVESLLDGLNSLVLDLDFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSRPPPTGKMPGAPETAPGDGAGASRQRKLEALIRDPRSPINVESLLDGLNSLVLDLDFP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 ALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 MSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ETGMVHCDTAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ETGMVHCDTAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 GTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIRQHPFFKNDQWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIRQHPFFKNDQWH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 WDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYYRENL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 WDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYYRENL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 LLSDSPSCRENDSIQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKT
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LLSDSPSCRETDSIQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 AKELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AKELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 EDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 DLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEEDLKNGKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEEDLKNGKI
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 LLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 IYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 QKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMN
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 LEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQK
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 KQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAIKAQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAIKAQF
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 EKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREKLTQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREKLTQQ
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 MIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIGSGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIGSGPG
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 DAEADDGFPESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNPYMVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DAEADDGFPESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNPYMVL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 DIDKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNYICHKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DIDKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNYICHKG
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 HEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCKVYYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCKVYYD
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 ISTAKNLLLLANSTEEQQKWVSRLVKKIPKKPPAPDPFARSSPRTSMKIQQNQSIRRPSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ISTAKNLLLLANSTEEQQKWVSRLVKKIPKKPPAPDPFARSSPRTSMKIQQNQSIRRPSR
1330 1340 1350 1360 1370 1380
pF1KA0 QLAPNKPS
::::::::
NP_004 QLAPNKPS
>>XP_016860867 (OMIM: 604002) PREDICTED: rho-associated (1404 aa)
initn: 9048 init1: 9048 opt: 9048 Z-score: 2652.9 bits: 503.3 E(85289): 5e-141
Smith-Waterman score: 9048; 99.9% identity (100.0% similar) in 1387 aa overlap (1-1387:1-1387)
10 20 30 40 50 60
pF1KA0 MSRPPPTGKMPGAPETAPGDGAGASRQRKLEALIRDPRSPINVESLLDGLNSLVLDLDFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSRPPPTGKMPGAPETAPGDGAGASRQRKLEALIRDPRSPINVESLLDGLNSLVLDLDFP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 ALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 MSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ETGMVHCDTAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETGMVHCDTAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 GTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIRQHPFFKNDQWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIRQHPFFKNDQWH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 WDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYYRENL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYYRENL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 LLSDSPSCRENDSIQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKT
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLSDSPSCRETDSIQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 AKELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 EDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 DLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEEDLKNGKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEEDLKNGKI
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 LLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 IYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 QKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMN
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 LEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQK
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 KQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAIKAQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAIKAQF
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 EKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREKLTQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREKLTQQ
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 MIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIGSGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIGSGPG
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 DAEADDGFPESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNPYMVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DAEADDGFPESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNPYMVL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 DIDKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNYICHKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIDKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNYICHKG
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 HEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCKVYYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCKVYYD
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 ISTAKNLLLLANSTEEQQKWVSRLVKKIPKKPPAPDPFARSSPRTSMKIQQNQSIRRPSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISTAKNLLLLANSTEEQQKWVSRLVKKIPKKPPAPDPFARSSPRTSMKIQQNQSIRRPSR
1330 1340 1350 1360 1370 1380
pF1KA0 QLAPNKPS
:::::::
XP_016 QLAPNKPRDEQSAWGNEGSMENSA
1390 1400
>>XP_005246247 (OMIM: 604002) PREDICTED: rho-associated (1417 aa)
initn: 9048 init1: 9048 opt: 9048 Z-score: 2652.8 bits: 503.3 E(85289): 5e-141
Smith-Waterman score: 9048; 99.9% identity (100.0% similar) in 1387 aa overlap (1-1387:1-1387)
10 20 30 40 50 60
pF1KA0 MSRPPPTGKMPGAPETAPGDGAGASRQRKLEALIRDPRSPINVESLLDGLNSLVLDLDFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSRPPPTGKMPGAPETAPGDGAGASRQRKLEALIRDPRSPINVESLLDGLNSLVLDLDFP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 ALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 MSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ETGMVHCDTAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ETGMVHCDTAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 GTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIRQHPFFKNDQWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIRQHPFFKNDQWH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 WDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYYRENL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYYRENL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 LLSDSPSCRENDSIQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKT
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLSDSPSCRETDSIQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 AKELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 EDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 DLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEEDLKNGKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEEDLKNGKI
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 LLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 IYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 QKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMN
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 LEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQK
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 KQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAIKAQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAIKAQF
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 EKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREKLTQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREKLTQQ
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 MIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIGSGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIGSGPG
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 DAEADDGFPESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNPYMVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DAEADDGFPESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNPYMVL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 DIDKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNYICHKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DIDKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNYICHKG
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 HEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCKVYYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCKVYYD
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 ISTAKNLLLLANSTEEQQKWVSRLVKKIPKKPPAPDPFARSSPRTSMKIQQNQSIRRPSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ISTAKNLLLLANSTEEQQKWVSRLVKKIPKKPPAPDPFARSSPRTSMKIQQNQSIRRPSR
1330 1340 1350 1360 1370 1380
pF1KA0 QLAPNKPS
:::::::
XP_005 QLAPNKPRLLDLAFKDWDWSFDDVDGGGDDDDDVFDF
1390 1400 1410
>>NP_001308572 (OMIM: 604002) rho-associated protein kin (1302 aa)
initn: 8483 init1: 8483 opt: 8483 Z-score: 2489.5 bits: 473.0 E(85289): 6.3e-132
Smith-Waterman score: 8483; 99.9% identity (100.0% similar) in 1302 aa overlap (87-1388:1-1302)
60 70 80 90 100 110
pF1KA0 LDFPALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQK
::::::::::::::::::::::::::::::
NP_001 MKAEDYDVVKVIGRGAFGEVQLVRHKASQK
10 20 30
120 130 140 150 160 170
pF1KA0 VYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGD
40 50 60 70 80 90
180 190 200 210 220 230
pF1KA0 LVNLMSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVNLMSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTC
100 110 120 130 140 150
240 250 260 270 280 290
pF1KA0 MKMDETGMVHCDTAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKMDETGMVHCDTAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYA
160 170 180 190 200 210
300 310 320 330 340 350
pF1KA0 DSLVGTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIRQHPFFKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSLVGTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIRQHPFFKN
220 230 240 250 260 270
360 370 380 390 400 410
pF1KA0 DQWHWDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQWHWDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYY
280 290 300 310 320 330
420 430 440 450 460 470
pF1KA0 RENLLLSDSPSCRENDSIQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTR
::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::
NP_001 RENLLLSDSPSCRETDSIQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTR
340 350 360 370 380 390
480 490 500 510 520 530
pF1KA0 LEKTAKELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEKTAKELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSL
400 410 420 430 440 450
540 550 560 570 580 590
pF1KA0 KDQLEDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDQLEDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLE
460 470 480 490 500 510
600 610 620 630 640 650
pF1KA0 SNNRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEEDLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNNRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEEDLK
520 530 540 550 560 570
660 670 680 690 700 710
pF1KA0 NGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLA
580 590 600 610 620 630
720 730 740 750 760 770
pF1KA0 DKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKIN
640 650 660 670 680 690
780 790 800 810 820 830
pF1KA0 ELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLME
700 710 720 730 740 750
840 850 860 870 880 890
pF1KA0 MKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKE
760 770 780 790 800 810
900 910 920 930 940 950
pF1KA0 LQQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMAR
820 830 840 850 860 870
960 970 980 990 1000 1010
pF1KA0 HKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAI
880 890 900 910 920 930
1020 1030 1040 1050 1060 1070
pF1KA0 KAQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREK
940 950 960 970 980 990
1080 1090 1100 1110 1120 1130
pF1KA0 LTQQMIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTQQMIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIG
1000 1010 1020 1030 1040 1050
1140 1150 1160 1170 1180 1190
pF1KA0 SGPGDAEADDGFPESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGPGDAEADDGFPESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNP
1060 1070 1080 1090 1100 1110
1200 1210 1220 1230 1240 1250
pF1KA0 YMVLDIDKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YMVLDIDKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNYI
1120 1130 1140 1150 1160 1170
1260 1270 1280 1290 1300 1310
pF1KA0 CHKGHEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CHKGHEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCK
1180 1190 1200 1210 1220 1230
1320 1330 1340 1350 1360 1370
pF1KA0 VYYDISTAKNLLLLANSTEEQQKWVSRLVKKIPKKPPAPDPFARSSPRTSMKIQQNQSIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYYDISTAKNLLLLANSTEEQQKWVSRLVKKIPKKPPAPDPFARSSPRTSMKIQQNQSIR
1240 1250 1260 1270 1280 1290
1380
pF1KA0 RPSRQLAPNKPS
::::::::::::
NP_001 RPSRQLAPNKPS
1300
>>XP_016860868 (OMIM: 604002) PREDICTED: rho-associated (1331 aa)
initn: 8478 init1: 8478 opt: 8478 Z-score: 2487.9 bits: 472.7 E(85289): 7.7e-132
Smith-Waterman score: 8478; 99.9% identity (100.0% similar) in 1301 aa overlap (87-1387:1-1301)
60 70 80 90 100 110
pF1KA0 LDFPALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQK
::::::::::::::::::::::::::::::
XP_016 MKAEDYDVVKVIGRGAFGEVQLVRHKASQK
10 20 30
120 130 140 150 160 170
pF1KA0 VYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGD
40 50 60 70 80 90
180 190 200 210 220 230
pF1KA0 LVNLMSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVNLMSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTC
100 110 120 130 140 150
240 250 260 270 280 290
pF1KA0 MKMDETGMVHCDTAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKMDETGMVHCDTAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYA
160 170 180 190 200 210
300 310 320 330 340 350
pF1KA0 DSLVGTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIRQHPFFKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSLVGTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIRQHPFFKN
220 230 240 250 260 270
360 370 380 390 400 410
pF1KA0 DQWHWDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQWHWDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYY
280 290 300 310 320 330
420 430 440 450 460 470
pF1KA0 RENLLLSDSPSCRENDSIQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTR
::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::
XP_016 RENLLLSDSPSCRETDSIQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTR
340 350 360 370 380 390
480 490 500 510 520 530
pF1KA0 LEKTAKELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEKTAKELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSL
400 410 420 430 440 450
540 550 560 570 580 590
pF1KA0 KDQLEDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDQLEDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLE
460 470 480 490 500 510
600 610 620 630 640 650
pF1KA0 SNNRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEEDLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNNRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEEDLK
520 530 540 550 560 570
660 670 680 690 700 710
pF1KA0 NGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLA
580 590 600 610 620 630
720 730 740 750 760 770
pF1KA0 DKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKIN
640 650 660 670 680 690
780 790 800 810 820 830
pF1KA0 ELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLME
700 710 720 730 740 750
840 850 860 870 880 890
pF1KA0 MKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKE
760 770 780 790 800 810
900 910 920 930 940 950
pF1KA0 LQQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMAR
820 830 840 850 860 870
960 970 980 990 1000 1010
pF1KA0 HKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAI
880 890 900 910 920 930
1020 1030 1040 1050 1060 1070
pF1KA0 KAQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREK
940 950 960 970 980 990
1080 1090 1100 1110 1120 1130
pF1KA0 LTQQMIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTQQMIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIG
1000 1010 1020 1030 1040 1050
1140 1150 1160 1170 1180 1190
pF1KA0 SGPGDAEADDGFPESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGPGDAEADDGFPESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNP
1060 1070 1080 1090 1100 1110
1200 1210 1220 1230 1240 1250
pF1KA0 YMVLDIDKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YMVLDIDKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNYI
1120 1130 1140 1150 1160 1170
1260 1270 1280 1290 1300 1310
pF1KA0 CHKGHEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CHKGHEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCK
1180 1190 1200 1210 1220 1230
1320 1330 1340 1350 1360 1370
pF1KA0 VYYDISTAKNLLLLANSTEEQQKWVSRLVKKIPKKPPAPDPFARSSPRTSMKIQQNQSIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VYYDISTAKNLLLLANSTEEQQKWVSRLVKKIPKKPPAPDPFARSSPRTSMKIQQNQSIR
1240 1250 1260 1270 1280 1290
1380
pF1KA0 RPSRQLAPNKPS
:::::::::::
XP_016 RPSRQLAPNKPRLLDLAFKDWDWSFDDVDGGGDDDDDVFDF
1300 1310 1320 1330
>>XP_011508719 (OMIM: 604002) PREDICTED: rho-associated (1331 aa)
initn: 8478 init1: 8478 opt: 8478 Z-score: 2487.9 bits: 472.7 E(85289): 7.7e-132
Smith-Waterman score: 8478; 99.9% identity (100.0% similar) in 1301 aa overlap (87-1387:1-1301)
60 70 80 90 100 110
pF1KA0 LDFPALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQK
::::::::::::::::::::::::::::::
XP_011 MKAEDYDVVKVIGRGAFGEVQLVRHKASQK
10 20 30
120 130 140 150 160 170
pF1KA0 VYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGD
40 50 60 70 80 90
180 190 200 210 220 230
pF1KA0 LVNLMSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVNLMSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTC
100 110 120 130 140 150
240 250 260 270 280 290
pF1KA0 MKMDETGMVHCDTAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKMDETGMVHCDTAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYA
160 170 180 190 200 210
300 310 320 330 340 350
pF1KA0 DSLVGTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIRQHPFFKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSLVGTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIRQHPFFKN
220 230 240 250 260 270
360 370 380 390 400 410
pF1KA0 DQWHWDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DQWHWDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYY
280 290 300 310 320 330
420 430 440 450 460 470
pF1KA0 RENLLLSDSPSCRENDSIQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTR
::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::
XP_011 RENLLLSDSPSCRETDSIQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTR
340 350 360 370 380 390
480 490 500 510 520 530
pF1KA0 LEKTAKELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEKTAKELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSL
400 410 420 430 440 450
540 550 560 570 580 590
pF1KA0 KDQLEDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDQLEDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLE
460 470 480 490 500 510
600 610 620 630 640 650
pF1KA0 SNNRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEEDLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNNRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEEDLK
520 530 540 550 560 570
660 670 680 690 700 710
pF1KA0 NGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLA
580 590 600 610 620 630
720 730 740 750 760 770
pF1KA0 DKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKIN
640 650 660 670 680 690
780 790 800 810 820 830
pF1KA0 ELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLME
700 710 720 730 740 750
840 850 860 870 880 890
pF1KA0 MKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKE
760 770 780 790 800 810
900 910 920 930 940 950
pF1KA0 LQQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMAR
820 830 840 850 860 870
960 970 980 990 1000 1010
pF1KA0 HKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAI
880 890 900 910 920 930
1020 1030 1040 1050 1060 1070
pF1KA0 KAQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREK
940 950 960 970 980 990
1080 1090 1100 1110 1120 1130
pF1KA0 LTQQMIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTQQMIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIG
1000 1010 1020 1030 1040 1050
1140 1150 1160 1170 1180 1190
pF1KA0 SGPGDAEADDGFPESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGPGDAEADDGFPESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNP
1060 1070 1080 1090 1100 1110
1200 1210 1220 1230 1240 1250
pF1KA0 YMVLDIDKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YMVLDIDKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNYI
1120 1130 1140 1150 1160 1170
1260 1270 1280 1290 1300 1310
pF1KA0 CHKGHEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CHKGHEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCK
1180 1190 1200 1210 1220 1230
1320 1330 1340 1350 1360 1370
pF1KA0 VYYDISTAKNLLLLANSTEEQQKWVSRLVKKIPKKPPAPDPFARSSPRTSMKIQQNQSIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VYYDISTAKNLLLLANSTEEQQKWVSRLVKKIPKKPPAPDPFARSSPRTSMKIQQNQSIR
1240 1250 1260 1270 1280 1290
1380
pF1KA0 RPSRQLAPNKPS
:::::::::::
XP_011 RPSRQLAPNKPRLLDLAFKDWDWSFDDVDGGGDDDDDVFDF
1300 1310 1320 1330
>>NP_005397 (OMIM: 601702) rho-associated protein kinase (1354 aa)
initn: 5013 init1: 2349 opt: 4176 Z-score: 1240.5 bits: 241.9 E(85289): 2.3e-62
Smith-Waterman score: 5872; 65.9% identity (86.1% similar) in 1361 aa overlap (25-1377:9-1344)
10 20 30 40 50 60
pF1KA0 MSRPPPTGKMPGAPETAPGDGAGASRQRKLEALIRDPRSPINVESLLDGLNSLVLDLDFP
.: .:.. :.:::.: .: . :::::..:: :::::
NP_005 MSTGDSFETRFEKMDNLLRDPKSEVNSDCLLDGLDALVYDLDFP
10 20 30 40
70 80 90 100 110 120
pF1KA0 ALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAM
::::::::::::.::. ..::: :.::::::.:::::::::::::::::::...:::::
NP_005 ALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAM
50 60 70 80 90 100
130 140 150 160 170 180
pF1KA0 KLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNL
110 120 130 140 150 160
190 200 210 220 230 240
pF1KA0 MSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMD
:::::::::::.:::::::::::::::::.:::::::::::::: ::::::::::::::.
NP_005 MSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMN
170 180 190 200 210 220
250 260 270 280 290 300
pF1KA0 ETGMVHCDTAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLV
. :::.:::::::::::::::::::::::.::::::::::::::::::::::::::::::
NP_005 KEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLV
230 240 250 260 270 280
310 320 330 340 350 360
pF1KA0 GTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIRQHPFFKNDQWH
:::::::.::::: ::.: .:::.::::::::::::::::::::::::..: :::::::
NP_005 GTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWA
290 300 310 320 330 340
370 380 390 400 410 420
pF1KA0 WDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYYRENL
:...:.:.:::::.::::::.:::::.:.:::. ::::::::::::::::.::::: .
NP_005 WETLRDTVAPVVPDLSSDIDTSNFDDLEEDKGEEETFPIPKAFVGNQLPFVGFTYYSNRR
350 360 370 380 390 400
430 440 450 460 470
pF1KA0 LLSDSPSCRENDSIQSRKNEES-QE-IQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLE
:: : ::. : . ..: :: .:: .: :::.: :::: :.:.::::.. : .:.
NP_005 YLS---SANPNDNRTSSNADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLD
410 420 430 440 450 460
480 490 500 510 520 530
pF1KA0 KTAKELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKD
: :::.:: . :...::.. :.:.:: ::::. ::::::..: .:.::.::.:..:::
NP_005 KIMKELDEEGNQRRNLESTVSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKD
470 480 490 500 510 520
540 550 560 570 580 590
pF1KA0 QLEDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESN
::::::: .::::...::..:::.::.:.: :::::::::.::::...: ::.:.::::
NP_005 QLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESL
530 540 550 560 570 580
600 610 620 630 640 650
pF1KA0 NRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEEDLKNG
::.::..: .::..: . .:.. .::. ::.::::: : ::.:.:::.:: .:.:..:.
NP_005 NRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHL
590 600 610 620 630 640
660 670 680 690 700 710
pF1KA0 KILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADK
: : ::: :... :. .. ::::.:.:::..:.:: .:: :::: :::.:::::.::
NP_005 KHNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDK
650 660 670 680 690 700
720 730 740 750 760 770
pF1KA0 NKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINEL
..::::::: :: :::::: ::: ..:.:: ... ::.::.:: ::::::::...:
NP_005 ---HQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHL
710 720 730 740 750
780 790 800 810 820 830
pF1KA0 LKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMK
.:. ....:.::::..:::..:: : ::.:: :. ....:: :::.::: : :.: :
NP_005 TGNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAK
760 770 780 790 800 810
840 850 860 870 880 890
pF1KA0 MNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQ
:: . :.: :. . .:::.::::::::::::::::::::.::::: :::.. :
NP_005 RLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNR---ENL
820 830 840 850 860 870
900 910 920 930 940 950
pF1KA0 QKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHK
.: ::::.:...::.::... :::.::::::.. :::: .: .:. :. .:..
NP_005 KKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYFELTQES-------KKAASRNR
880 890 900 910 920
960 970 980 990 1000 1010
pF1KA0 QELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAIKA
::.:.:: :.. :::.: ::.:. : :.:::..:.: ..:. . :.:::: .::
NP_005 QEITDKDHTVSRLEEANSMLTKDIEILRRENEELTEKMKKAEEEYKLEKEEEISN--LKA
930 940 950 960 970 980
1020 1030 1040 1050 1060 1070
pF1KA0 QFEKQLLTERTLKTQAVNKLAEIMNRKE---PVKRGNDTDVRRKEKENRKLHMELKSERE
:::.. ::::::::::::::::::::. :..: :.:.::::::::..::..:::
NP_005 AFEKNINTERTLKTQAVNKLAEIMNRKDFKIDRKKANTQDLRKKEKENRKLQLELNQERE
990 1000 1010 1020 1030 1040
1080 1090 1100 1110 1120 1130
pF1KA0 KLTQQMIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSI
:..:...:.:::::.::::..:: : :::: : ::.:::::::..: : ::.:.
NP_005 KFNQMVVKHQKELNDMQAQLVEECAHRNELQMQLASKESDIEQLRAKLLDLS---DSTSV
1050 1060 1070 1080 1090 1100
1140 1150 1160 1170 1180 1190
pF1KA0 GSGPGDAEADDGFPESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSN
.: :. :.: ..::::.:::::.: :.: :..:: :.::.:::::::::..::::::::
NP_005 ASFPSADETDGNLPESRIEGWLSVPNRGNIKRYGWKKQYVVVSSKKILFYNDEQDKEQSN
1110 1120 1130 1140 1150 1160
1200 1210 1220 1230 1240 1250
pF1KA0 PYMVLDIDKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPV--GEKS
: :::::::::::::::: :::::...:::.::::::::::: .:. : .::: .::.
NP_005 PSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILYANEGECRKDVE--MEPVQQAEKT
1170 1180 1190 1200 1210 1220
1260 1270 1280 1290 1300 1310
pF1KA0 NYICHKGHEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIA
:. ::::::::::::::.::.:: :::::.:::::::::::::.:::.::.::::..:
NP_005 NFQNHKGHEFIPTLYHFPANCDACAKPLWHVFKPPPALECRRCHVKCHRDHLDKKEDLIC
1230 1240 1250 1260 1270 1280
1320 1330 1340 1350 1360 1370
pF1KA0 PCKVYYDISTAKNLLLLANSTEEQQKWVSRLVKKIPKKPPAPDPFARSSPRT-SMKIQQN
:::: ::...:...:::: : .::.:::..:::::::.::. :.:.:::: : . :
NP_005 PCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNPPSG--FVRASPRTLSTRSTAN
1290 1300 1310 1320 1330
1380
pF1KA0 QSIRRPSRQLAPNKPS
::.:.
NP_005 QSFRKVVKNTSGKTS
1340 1350
>>XP_011524439 (OMIM: 601702) PREDICTED: rho-associated (891 aa)
initn: 2535 init1: 1238 opt: 1918 Z-score: 588.3 bits: 120.7 E(85289): 5e-26
Smith-Waterman score: 3385; 59.2% identity (83.5% similar) in 902 aa overlap (482-1377:2-881)
460 470 480 490 500 510
pF1KA0 LEEHLSNEMQAKEELEQKCKSVNTRLEKTAKELEEEITLRKSVESALRQLEREKALLQHK
:::.:: . :...::.. :.:.:: ::::.
XP_011 MKELDEEGNQRRNLESTVSQIEKEKMLLQHR
10 20 30
520 530 540 550 560 570
pF1KA0 NAEYQRKADHEADKKRNLENDVNSLKDQLEDLKKRNQNSQISTEKVNQLQRQLDETNALL
::::::..: .:.::.::.:..:::::::::: .::::...::..:::.::.:.: ::
XP_011 INEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLL
40 50 60 70 80 90
580 590 600 610 620 630
pF1KA0 RTESDTAARLRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLKLEKEFINLQSALESER
:::::::.::::...: ::.:.:::: ::.::..: .::..: . .:.. .::. ::.::
XP_011 RTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKDYYQLQAILEAER
100 110 120 130 140 150
640 650 660 670 680 690
pF1KA0 RDRTHGSEIINDLQGRICGLEEDLKNGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMT
::: : ::.:.:::.:: .:.:..:. : : ::: :... :. .. ::::.:.:::..
XP_011 RDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEIDLN
160 170 180 190 200 210
700 710 720 730 740 750
pF1KA0 YQLKVIQQSLEQEEAEHKATKARLADKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVE
:.:: .:: :::: :::.:::::.:: ..::::::: :: :::::: ::: ..:.:
XP_011 YKLKSLQQRLEQEVNEHKVTKARLTDK---HQSIEEAKSVAMCEMEKKLKEEREAREKAE
220 230 240 250 260
760 770 780 790 800 810
pF1KA0 NLLLEAEKRCSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLK
: ... ::.::.:: ::::::::...: .:. ....:.::::..:::..:: : ::.::
XP_011 NRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELK
270 280 290 300 310 320
820 830 840 850 860 870
pF1KA0 MQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQY
:. ....:: :::.::: : :.: : :: . :.: :. . .:::.:::::::::::
XP_011 TQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQY
330 340 350 360 370 380
880 890 900 910 920 930
pF1KA0 FSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKADSEQLARSI
:::::::::.::::: :::. .: .: ::::.:...::.::... :::.::::::..
XP_011 FSTLYKTQVKELKEEIEEKN---RENLKKIQELQNEKETLATQLDLAETKAESEQLARGL
390 400 410 420 430 440
940 950 960 970 980 990
pF1KA0 AEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEE
:::: .: .:. :. .:..::.:.:: :.. :::.: ::.:. : :.::
XP_011 LEEQYFELTQES-------KKAASRNRQEITDKDHTVSRLEEANSMLTKDIEILRRENEE
450 460 470 480 490
1000 1010 1020 1030 1040
pF1KA0 LNNKLKDVQEQLSRLKDEEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIMNRKE---PV
:..:.: ..:. . :.:::: .:: :::.. ::::::::::::::::::::.
XP_011 LTEKMKKAEEEYKLEKEEEISN--LKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKIDR
500 510 520 530 540 550
1050 1060 1070 1080 1090 1100
pF1KA0 KRGNDTDVRRKEKENRKLHMELKSEREKLTQQMIKYQKELNEMQAQIAEESQIRIELQMT
:..: :.:.::::::::..::..::::..:...:.:::::.::::..:: : ::::
XP_011 KKANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECAHRNELQMQ
560 570 580 590 600 610
1110 1120 1130 1140 1150 1160
pF1KA0 LDSKDSDIEQLRSQLQALHIGLDSSSIGSGPGDAEADDGFPESRLEGWLSLPVRNNTKKF
: ::.:::::::..: : ::.:..: :. :.: ..::::.:::::.: :.: :..
XP_011 LASKESDIEQLRAKLLDLS---DSTSVASFPSADETDGNLPESRIEGWLSVPNRGNIKRY
620 630 640 650 660 670
1170 1180 1190 1200 1210 1220
pF1KA0 GWVKKYVIVSSKKILFYDSEQDKEQSNPYMVLDIDKLFHVRPVTQTDVYRADAKEIPRIF
:: :.::.:::::::::..::::::::: :::::::::::::::: :::::...:::.::
XP_011 GWKKQYVVVSSKKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIF
680 690 700 710 720 730
1230 1240 1250 1260 1270 1280
pF1KA0 QILYANEGESKKEQEFPVEPV--GEKSNYICHKGHEFIPTLYHFPTNCEACMKPLWHMFK
::::::::: .:. : .::: .::.:. ::::::::::::::.::.:: :::::.::
XP_011 QILYANEGECRKDVE--MEPVQQAEKTNFQNHKGHEFIPTLYHFPANCDACAKPLWHVFK
740 750 760 770 780 790
1290 1300 1310 1320 1330 1340
pF1KA0 PPPALECRRCHIKCHKDHMDKKEEIIAPCKVYYDISTAKNLLLLANSTEEQQKWVSRLVK
:::::::::::.:::.::.::::..: :::: ::...:...:::: : .::.:::..:::
XP_011 PPPALECRRCHVKCHRDHLDKKEDLICPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVK
800 810 820 830 840 850
1350 1360 1370 1380
pF1KA0 KIPKKPPAPDPFARSSPRT-SMKIQQNQSIRRPSRQLAPNKPS
::::.::. :.:.:::: : . :::.:.
XP_011 KIPKNPPS--GFVRASPRTLSTRSTANQSFRKVVKNTSGKTS
860 870 880 890
>>XP_011542610 (OMIM: 603412) PREDICTED: serine/threonin (1783 aa)
initn: 1310 init1: 449 opt: 1570 Z-score: 483.2 bits: 102.2 E(85289): 3.6e-20
Smith-Waterman score: 1642; 29.5% identity (62.4% similar) in 1273 aa overlap (22-1230:2-1216)
10 20 30 40 50
pF1KA0 MSRPPPTGKMPGAPETAPGDGAGASRQRKLEALIRDPRSPIN-----VESLLDGLNSLVL
.: : :.:: .: : . : ::.::: : :
XP_011 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYD
10 20 30 40
60 70 80 90 100 110
pF1KA0 DLDFPALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQ
. . ::..::: ..:. . ...:.. .... ::....::::::::::: .:. : ..
XP_011 ECNNSPLRREKNILEYLEWAKPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNAD
50 60 70 80 90 100
120 130 140 150 160 170
pF1KA0 KVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGG
::.:::.:.:.::.::...: : ::::... ... :.. : :::::: ::.::.:. ::
XP_011 KVFAMKILNKWEMLKRAETACFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGG
110 120 130 140 150 160
180 190 200 210 220 230
pF1KA0 DLVNLMSNYD--VPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADF
::..:.:... .:: :.:: ::.:.:.:..:.. .:::.::::.:.: .::..::::
XP_011 DLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADF
170 180 190 200 210 220
240 250 260 270 280 290
pF1KA0 GTCMKMDETGMVHCDTAVGTPDYISPEVLKS-QGGDGFYGRECDWWSVGVFLYEMLVGDT
:.:.:. : : :. ..:::::::::::.:.. . : : :: ::::::.:: .:::: :.:
XP_011 GSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGET
230 240 250 260 270 280
300 310 320 330 340 350
pF1KA0 PFYADSLVGTYSKIMDHKNSLCFPEDA-EISKHAKNLICAFLTDREVRLGRNGVEEIRQH
::::.::: ::.:::.::. . :: .. ..:..::.:: .. .:: :::.::.:....:
XP_011 PFYAESLVETYGKIMNHKERFQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKH
290 300 310 320 330 340
360 370 380 390 400
pF1KA0 PFFKNDQWHWDNIRETAAPVVPELSSDIDSSNFDDIEDDK-GDVETFPIPK--AFVGNQL
:::.. . :::::. :: .::.:: :.:::: ..:: . ::.: : :: :..:
XP_011 PFFSGID--WDNIRNCEAPYIPEVSSPTDTSNFD-VDDDCLKNSETMPPPTHTAFSGHHL
350 360 370 380 390
410 420 430 440 450 460
pF1KA0 PFIGFTYYRENLLLSDSPSCRENDSIQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQ
::.:::: . .::: :: .. . : ... .... :.:.. : : :.
XP_011 PFVGFTY-TSSCVLSDR-SC-----LRVTAGPTSLDLD---VNVQRTLDNNL-ATEAYER
400 410 420 430 440
470 480 490 500 510 520
pF1KA0 KCKSVNTRLEKTAKELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRN
. : :::. :: .. :..:.... .:: :.... : ...
XP_011 RIK----RLEQEKLELSRK--LQESTQTV-------QAL-QYSTV------DGPLTASKD
450 460 470 480
530 540 550 560 570 580
pF1KA0 LENDVNSLKDQLEDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAES
:: ...::...: :.:. .: ..:..::.:.::. : : : : .:. .:
XP_011 LE--IKNLKEEIEKLRKQVTES-------SHLEQQLEEANAV-RQELDDA--FRQIKAYE
490 500 510 520 530
590 600 610 620 630 640
pF1KA0 SKQIQQLESNNRDLQDKNCLLETAKLKLE-KEFINLQSALESERRDRTHGSEIINDLQGR
:::. :... .:: .:. . . .:: . ::. . . . .. . .: ...:. .
XP_011 -KQIKTLQQEREDL-NKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQ
540 550 560 570 580 590
650 660 670 680 690 700
pF1KA0 ICGLEEDLKNGKILLAKVELEKRQLQERFTDLEKEKSNMEIDM-TYQLKVIQQSLEQEEA
: . ... . . : . ..:.... :. :...:. . .. .. .:..
XP_011 KQKLARHVRDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQS
600 610 620 630 640 650
710 720 730 740 750 760
pF1KA0 EHKATKARLADKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAE--KRCSLL
:: . . . .. ..: . . : .... . .: .: .... : : :: ..
XP_011 EHYSKQLENELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEK-KSIFYEEELSKREGIH
660 670 680 690 700 710
770 780 790 800 810 820
pF1KA0 DCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQ---ETQ-KRCLTQNDLKMQTQQVNTL
..:. ...... :. .::... : :.:. :.: .: ....:.: .. ..:
XP_011 ANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVL
720 730 740 750 760 770
830 840 850 860
pF1KA0 KMSE-KQLKQENNHLMEMKMNLEKQNAELRKERQD-AD---------GQMKEL----QDQ
: :.: .: ..: . :: .: .:..: .: :: .:. :. .:.
XP_011 LTEENKKLTSELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDE
780 790 800 810 820 830
870 880 890 900 910 920
pF1KA0 LEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQD-ERDSLAAQLEITLTKADS
.:. :...: . ...:: : ....:: . . ... . ...:.::. . :.
XP_011 KDARGYLQALASKMTEEL--EALRNSSLGTRATDMPWKMRRFAKLDMSARLELQ-SALDA
840 850 860 870 880
930 940 950 960 970
pF1KA0 EQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIASLEE-----------
: :.. .:. . .. .:. : ..:. .. . :.: . : . ::
XP_011 EIRAKQAIQEELNKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQD
890 900 910 920 930 940
980 990 1000 1010 1020
pF1KA0 TNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAIKAQFEKQLLTERT----
..... . . . .. ......... . .: . :.. . . .. .. .: :
XP_011 SQHSFLAFLNTPTDALDQFEDSFSSSSSSLIDFLDDRSPSCTPASKGRRTDPVENTYVWN
950 960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KA0 ----LKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKS---EREKLTQQMI
.. :. . .. :::: ..: . . :: .. ..: : ..
XP_011 PSVKFHIQSRSTSPSTSSEAEPVKTVDSTPLSVHTPTLRKKGCPGSTGFPPKRKTHQFFV
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KA0 K-YQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIGSGPGD
: . . : . :: . . . . : . . . . .... ::
XP_011 KSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTK---GPLG
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KA0 AEADDGFPESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNPYMVL-
. . :. . :: . .: ..:: :: . .:: . :...:: . : :.: .:.
XP_011 IDPQKGIGTAY-EGHVRIPKPAGVKK-GWQRALAIVCDFKLFLYDIAEGKA-SQPSVVIS
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250
pF1KA0 ---DI-DKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNYI
:. :. : : : .:: .:. :.:: ::..
XP_011 QVIDMRDEEFSVSSVLASDVIHASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNK
1190 1200 1210 1220 1230 1240
1260 1270 1280 1290 1300 1310
pF1KA0 CHKGHEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCK
XP_011 WVGVLSELHKILKKNKFRDRSVYVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFV
1250 1260 1270 1280 1290 1300
>>XP_011542608 (OMIM: 603412) PREDICTED: serine/threonin (1845 aa)
initn: 1310 init1: 449 opt: 1570 Z-score: 483.0 bits: 102.2 E(85289): 3.7e-20
Smith-Waterman score: 1642; 29.5% identity (62.4% similar) in 1273 aa overlap (22-1230:2-1216)
10 20 30 40 50
pF1KA0 MSRPPPTGKMPGAPETAPGDGAGASRQRKLEALIRDPRSPIN-----VESLLDGLNSLVL
.: : :.:: .: : . : ::.::: : :
XP_011 MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYD
10 20 30 40
60 70 80 90 100 110
pF1KA0 DLDFPALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQ
. . ::..::: ..:. . ...:.. .... ::....::::::::::: .:. : ..
XP_011 ECNNSPLRREKNILEYLEWAKPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNAD
50 60 70 80 90 100
120 130 140 150 160 170
pF1KA0 KVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGG
::.:::.:.:.::.::...: : ::::... ... :.. : :::::: ::.::.:. ::
XP_011 KVFAMKILNKWEMLKRAETACFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGG
110 120 130 140 150 160
180 190 200 210 220 230
pF1KA0 DLVNLMSNYD--VPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADF
::..:.:... .:: :.:: ::.:.:.:..:.. .:::.::::.:.: .::..::::
XP_011 DLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADF
170 180 190 200 210 220
240 250 260 270 280 290
pF1KA0 GTCMKMDETGMVHCDTAVGTPDYISPEVLKS-QGGDGFYGRECDWWSVGVFLYEMLVGDT
:.:.:. : : :. ..:::::::::::.:.. . : : :: ::::::.:: .:::: :.:
XP_011 GSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGET
230 240 250 260 270 280
300 310 320 330 340 350
pF1KA0 PFYADSLVGTYSKIMDHKNSLCFPEDA-EISKHAKNLICAFLTDREVRLGRNGVEEIRQH
::::.::: ::.:::.::. . :: .. ..:..::.:: .. .:: :::.::.:....:
XP_011 PFYAESLVETYGKIMNHKERFQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKH
290 300 310 320 330 340
360 370 380 390 400
pF1KA0 PFFKNDQWHWDNIRETAAPVVPELSSDIDSSNFDDIEDDK-GDVETFPIPK--AFVGNQL
:::.. . :::::. :: .::.:: :.:::: ..:: . ::.: : :: :..:
XP_011 PFFSGID--WDNIRNCEAPYIPEVSSPTDTSNFD-VDDDCLKNSETMPPPTHTAFSGHHL
350 360 370 380 390
410 420 430 440 450 460
pF1KA0 PFIGFTYYRENLLLSDSPSCRENDSIQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQ
::.:::: . .::: :: .. . : ... .... :.:.. : : :.
XP_011 PFVGFTY-TSSCVLSDR-SC-----LRVTAGPTSLDLD---VNVQRTLDNNL-ATEAYER
400 410 420 430 440
470 480 490 500 510 520
pF1KA0 KCKSVNTRLEKTAKELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRN
. : :::. :: .. :..:.... .:: :.... : ...
XP_011 RIK----RLEQEKLELSRK--LQESTQTV-------QAL-QYSTV------DGPLTASKD
450 460 470 480
530 540 550 560 570 580
pF1KA0 LENDVNSLKDQLEDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAES
:: ...::...: :.:. .: ..:..::.:.::. : : : : .:. .:
XP_011 LE--IKNLKEEIEKLRKQVTES-------SHLEQQLEEANAV-RQELDDA--FRQIKAYE
490 500 510 520 530
590 600 610 620 630 640
pF1KA0 SKQIQQLESNNRDLQDKNCLLETAKLKLE-KEFINLQSALESERRDRTHGSEIINDLQGR
:::. :... .:: .:. . . .:: . ::. . . . .. . .: ...:. .
XP_011 -KQIKTLQQEREDL-NKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQ
540 550 560 570 580 590
650 660 670 680 690 700
pF1KA0 ICGLEEDLKNGKILLAKVELEKRQLQERFTDLEKEKSNMEIDM-TYQLKVIQQSLEQEEA
: . ... . . : . ..:.... :. :...:. . .. .. .:..
XP_011 KQKLARHVRDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQS
600 610 620 630 640 650
710 720 730 740 750 760
pF1KA0 EHKATKARLADKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAE--KRCSLL
:: . . . .. ..: . . : .... . .: .: .... : : :: ..
XP_011 EHYSKQLENELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEK-KSIFYEEELSKREGIH
660 670 680 690 700 710
770 780 790 800 810 820
pF1KA0 DCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQ---ETQ-KRCLTQNDLKMQTQQVNTL
..:. ...... :. .::... : :.:. :.: .: ....:.: .. ..:
XP_011 ANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVL
720 730 740 750 760 770
830 840 850 860
pF1KA0 KMSE-KQLKQENNHLMEMKMNLEKQNAELRKERQD-AD---------GQMKEL----QDQ
: :.: .: ..: . :: .: .:..: .: :: .:. :. .:.
XP_011 LTEENKKLTSELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDE
780 790 800 810 820 830
870 880 890 900 910 920
pF1KA0 LEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQD-ERDSLAAQLEITLTKADS
.:. :...: . ...:: : ....:: . . ... . ...:.::. . :.
XP_011 KDARGYLQALASKMTEEL--EALRNSSLGTRATDMPWKMRRFAKLDMSARLELQ-SALDA
840 850 860 870 880
930 940 950 960 970
pF1KA0 EQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIASLEE-----------
: :.. .:. . .. .:. : ..:. .. . :.: . : . ::
XP_011 EIRAKQAIQEELNKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQD
890 900 910 920 930 940
980 990 1000 1010 1020
pF1KA0 TNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAIKAQFEKQLLTERT----
..... . . . .. ......... . .: . :.. . . .. .. .: :
XP_011 SQHSFLAFLNTPTDALDQFEDSFSSSSSSLIDFLDDRSPSCTPASKGRRTDPVENTYVWN
950 960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KA0 ----LKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKS---EREKLTQQMI
.. :. . .. :::: ..: . . :: .. ..: : ..
XP_011 PSVKFHIQSRSTSPSTSSEAEPVKTVDSTPLSVHTPTLRKKGCPGSTGFPPKRKTHQFFV
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KA0 K-YQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIGSGPGD
: . . : . :: . . . . : . . . . .... ::
XP_011 KSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTK---GPLG
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KA0 AEADDGFPESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNPYMVL-
. . :. . :: . .: ..:: :: . .:: . :...:: . : :.: .:.
XP_011 IDPQKGIGTAY-EGHVRIPKPAGVKK-GWQRALAIVCDFKLFLYDIAEGKA-SQPSVVIS
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250
pF1KA0 ---DI-DKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNYI
:. :. : : : .:: .:. :.:: ::..
XP_011 QVIDMRDEEFSVSSVLASDVIHASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNK
1190 1200 1210 1220 1230 1240
1260 1270 1280 1290 1300 1310
pF1KA0 CHKGHEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCK
XP_011 WVGVLSELHKILKKNKFRDRSVYVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFV
1250 1260 1270 1280 1290 1300
1388 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 09:58:16 2016 done: Thu Nov 3 09:58:19 2016
Total Scan time: 19.250 Total Display time: 0.610
Function used was FASTA [36.3.4 Apr, 2011]