FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0597, 910 aa
1>>>pF1KA0597 910 - 910 aa - 910 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.2114+/-0.00042; mu= 17.7335+/- 0.026
mean_var=129.9156+/-25.398, 0's: 0 Z-trim(115.9): 66 B-trim: 29 in 1/49
Lambda= 0.112524
statistics sampled from 26537 (26603) to 26537 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.643), E-opt: 0.2 (0.312), width: 16
Scan time: 14.170
The best scores are: opt bits E(85289)
NP_005876 (OMIM: 613297) E3 ubiquitin-protein liga ( 910) 6182 1016.0 0
XP_011512234 (OMIM: 613297) PREDICTED: E3 ubiquiti ( 842) 5672 933.2 0
NP_001257589 (OMIM: 613297) E3 ubiquitin-protein l ( 862) 5380 885.8 0
NP_001257590 (OMIM: 613297) E3 ubiquitin-protein l ( 805) 5369 884.0 0
XP_011512236 (OMIM: 613297) PREDICTED: E3 ubiquiti ( 791) 5213 858.6 0
XP_011512238 (OMIM: 613297) PREDICTED: E3 ubiquiti ( 637) 4341 717.0 7.3e-206
XP_011512239 (OMIM: 613297) PREDICTED: E3 ubiquiti ( 510) 3398 563.8 7.6e-160
XP_016864433 (OMIM: 613297) PREDICTED: E3 ubiquiti ( 460) 3075 511.3 4.3e-144
XP_011537797 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 291) 260 54.1 1.1e-06
NP_001002266 (OMIM: 613335) E3 ubiquitin-protein l ( 291) 260 54.1 1.1e-06
XP_016871383 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 291) 260 54.1 1.1e-06
NP_659458 (OMIM: 613335) E3 ubiquitin-protein liga ( 291) 260 54.1 1.1e-06
NP_060393 (OMIM: 613331) E3 ubiquitin-protein liga ( 272) 258 53.8 1.4e-06
XP_016863824 (OMIM: 613331) PREDICTED: E3 ubiquiti ( 285) 258 53.8 1.4e-06
XP_016863825 (OMIM: 613331) PREDICTED: E3 ubiquiti ( 285) 258 53.8 1.4e-06
XP_016863823 (OMIM: 613331) PREDICTED: E3 ubiquiti ( 289) 258 53.8 1.4e-06
NP_001159845 (OMIM: 613331) E3 ubiquitin-protein l ( 289) 258 53.8 1.4e-06
XP_011537795 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 573) 257 53.9 2.6e-06
NP_001269795 (OMIM: 613335) E3 ubiquitin-protein l ( 573) 257 53.9 2.6e-06
XP_011537794 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 573) 257 53.9 2.6e-06
XP_006717767 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 573) 257 53.9 2.6e-06
XP_011537796 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 573) 257 53.9 2.6e-06
XP_005271861 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 573) 257 53.9 2.6e-06
XP_011530357 (OMIM: 613331) PREDICTED: E3 ubiquiti ( 545) 249 52.6 6.1e-06
XP_016864504 (OMIM: 613333) PREDICTED: E3 ubiquiti ( 154) 210 45.7 0.0002
NP_848545 (OMIM: 613333) E3 ubiquitin-protein liga ( 253) 210 46.0 0.00029
XP_011541432 (OMIM: 613333) PREDICTED: E3 ubiquiti ( 280) 210 46.0 0.00031
XP_011541433 (OMIM: 613333) PREDICTED: E3 ubiquiti ( 280) 210 46.0 0.00031
XP_011541431 (OMIM: 613333) PREDICTED: E3 ubiquiti ( 280) 210 46.0 0.00031
XP_005257163 (OMIM: 613337) PREDICTED: probable E3 ( 752) 210 46.4 0.00061
XP_005257160 (OMIM: 613337) PREDICTED: probable E3 ( 799) 210 46.5 0.00064
NP_001275709 (OMIM: 613337) probable E3 ubiquitin- ( 799) 210 46.5 0.00064
XP_011522739 (OMIM: 613337) PREDICTED: probable E3 ( 807) 210 46.5 0.00065
NP_001094345 (OMIM: 613337) probable E3 ubiquitin- ( 808) 210 46.5 0.00065
NP_689811 (OMIM: 613337) probable E3 ubiquitin-pro ( 808) 210 46.5 0.00065
XP_005257159 (OMIM: 613337) PREDICTED: probable E3 ( 824) 210 46.5 0.00066
XP_005257157 (OMIM: 613337) PREDICTED: probable E3 ( 825) 210 46.5 0.00066
XP_011522738 (OMIM: 613337) PREDICTED: probable E3 ( 825) 210 46.5 0.00066
NP_001275708 (OMIM: 613337) probable E3 ubiquitin- ( 846) 210 46.5 0.00067
XP_011522737 (OMIM: 613337) PREDICTED: probable E3 ( 862) 210 46.5 0.00068
XP_005257155 (OMIM: 613337) PREDICTED: probable E3 ( 862) 210 46.5 0.00068
XP_005257153 (OMIM: 613337) PREDICTED: probable E3 ( 863) 210 46.5 0.00068
XP_005257152 (OMIM: 613337) PREDICTED: probable E3 ( 863) 210 46.5 0.00068
XP_005257154 (OMIM: 613337) PREDICTED: probable E3 ( 863) 210 46.5 0.00068
NP_001005416 (OMIM: 613332) E3 ubiquitin-protein l ( 176) 190 42.6 0.0021
XP_006722826 (OMIM: 613332) PREDICTED: E3 ubiquiti ( 176) 190 42.6 0.0021
XP_016882342 (OMIM: 613332) PREDICTED: E3 ubiquiti ( 246) 190 42.7 0.0027
NP_057580 (OMIM: 613332) E3 ubiquitin-protein liga ( 246) 190 42.7 0.0027
NP_001005415 (OMIM: 613332) E3 ubiquitin-protein l ( 246) 190 42.7 0.0027
XP_011526348 (OMIM: 613332) PREDICTED: E3 ubiquiti ( 256) 190 42.7 0.0027
>>NP_005876 (OMIM: 613297) E3 ubiquitin-protein ligase M (910 aa)
initn: 6182 init1: 6182 opt: 6182 Z-score: 5430.1 bits: 1016.0 E(85289): 0
Smith-Waterman score: 6182; 100.0% identity (100.0% similar) in 910 aa overlap (1-910:1-910)
10 20 30 40 50 60
pF1KA0 MDTAEEDICRVCRSEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MDTAEEDICRVCRSEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 FTPIYSPDMPSRLPIQDIFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FTPIYSPDMPSRLPIQDIFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 PPFNAAGHHQNEAPAGGNGAENVAADQPANPPAENAVVGENPDAQDDQAEEEEEDNEEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PPFNAAGHHQNEAPAGGNGAENVAADQPANPPAENAVVGENPDAQDDQAEEEEEDNEEED
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 DAGVEDAADANNGAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DAGVEDAADANNGAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 ILVFAFCPYHIGHFSLVGLGFEEHVQASHFEGLITTIVGYILLAITLIICHGLATLVKFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ILVFAFCPYHIGHFSLVGLGFEEHVQASHFEGLITTIVGYILLAITLIICHGLATLVKFH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 RSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 MFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 ILSVIVFGSIVLLMLWLPIRIIKSVLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ILSVIVFGSIVLLMLWLPIRIIKSVLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 EQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEENENSANQQVNNNQHARNNNAIPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEENENSANQQVNNNQHARNNNAIPVV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 GEGLHAAHQAILQQGGPVGFQPYRRPLNFPLRIFLLIVFMCITLLIASLICLTLPVFAGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GEGLHAAHQAILQQGGPVGFQPYRRPLNFPLRIFLLIVFMCITLLIASLICLTLPVFAGR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 WLMSFWTGTAKIHELYTAACGLYVCWLTIRAVTVMVAWMPQGRRVIFQKVKEWSLMIMKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 WLMSFWTGTAKIHELYTAACGLYVCWLTIRAVTVMVAWMPQGRRVIFQKVKEWSLMIMKT
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 LIVAVLLAGVVPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LIVAVLLAGVVPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 PQWWLKTVIEQVYANGIRNIDLHYIVRKLAAPVISVLLLSLCVPYVIASGVVPLLGVTAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PQWWLKTVIEQVYANGIRNIDLHYIVRKLAAPVISVLLLSLCVPYVIASGVVPLLGVTAE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 MQNLVHRRIYPFLLMVVVLMAILSFQVRQFKRLYEHIKNDKYLVGQRLVNYERKSGKQGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MQNLVHRRIYPFLLMVVVLMAILSFQVRQFKRLYEHIKNDKYLVGQRLVNYERKSGKQGS
850 860 870 880 890 900
910
pF1KA0 SPPPPQSSQE
::::::::::
NP_005 SPPPPQSSQE
910
>>XP_011512234 (OMIM: 613297) PREDICTED: E3 ubiquitin-pr (842 aa)
initn: 5672 init1: 5672 opt: 5672 Z-score: 4983.1 bits: 933.2 E(85289): 0
Smith-Waterman score: 5672; 100.0% identity (100.0% similar) in 842 aa overlap (69-910:1-842)
40 50 60 70 80 90
pF1KA0 CLVQWLKHSRKEYCELCKHRFAFTPIYSPDMPSRLPIQDIFAGLVTSIGTAIRYWFHYTL
::::::::::::::::::::::::::::::
XP_011 MPSRLPIQDIFAGLVTSIGTAIRYWFHYTL
10 20 30
100 110 120 130 140 150
pF1KA0 VAFAWLGVVPLTACRIYKCLFTGSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAFAWLGVVPLTACRIYKCLFTGSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFI
40 50 60 70 80 90
160 170 180 190 200 210
pF1KA0 SLVWLREQIVHGGAPIWLEHAAPPFNAAGHHQNEAPAGGNGAENVAADQPANPPAENAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLVWLREQIVHGGAPIWLEHAAPPFNAAGHHQNEAPAGGNGAENVAADQPANPPAENAVV
100 110 120 130 140 150
220 230 240 250 260 270
pF1KA0 GENPDAQDDQAEEEEEDNEEEDDAGVEDAADANNGAQDDMNWNALEWDRAAEELTWERML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GENPDAQDDQAEEEEEDNEEEDDAGVEDAADANNGAQDDMNWNALEWDRAAEELTWERML
160 170 180 190 200 210
280 290 300 310 320 330
pF1KA0 GLDGSLVFLEHVFWVVSLNTLFILVFAFCPYHIGHFSLVGLGFEEHVQASHFEGLITTIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLDGSLVFLEHVFWVVSLNTLFILVFAFCPYHIGHFSLVGLGFEEHVQASHFEGLITTIV
220 230 240 250 260 270
340 350 360 370 380 390
pF1KA0 GYILLAITLIICHGLATLVKFHRSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GYILLAITLIICHGLATLVKFHRSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICS
280 290 300 310 320 330
400 410 420 430 440 450
pF1KA0 LEMFDATLKDRELSFQSAPGTTMFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEMFDATLKDRELSFQSAPGTTMFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLN
340 350 360 370 380 390
460 470 480 490 500 510
pF1KA0 DPDFNPVQEMIHLPIYRHLRRFILSVIVFGSIVLLMLWLPIRIIKSVLPNFLPYNVMLYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPDFNPVQEMIHLPIYRHLRRFILSVIVFGSIVLLMLWLPIRIIKSVLPNFLPYNVMLYS
400 410 420 430 440 450
520 530 540 550 560 570
pF1KA0 DAPVSELSLELLLLQVVLPALLEQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEENE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAPVSELSLELLLLQVVLPALLEQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEENE
460 470 480 490 500 510
580 590 600 610 620 630
pF1KA0 NSANQQVNNNQHARNNNAIPVVGEGLHAAHQAILQQGGPVGFQPYRRPLNFPLRIFLLIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSANQQVNNNQHARNNNAIPVVGEGLHAAHQAILQQGGPVGFQPYRRPLNFPLRIFLLIV
520 530 540 550 560 570
640 650 660 670 680 690
pF1KA0 FMCITLLIASLICLTLPVFAGRWLMSFWTGTAKIHELYTAACGLYVCWLTIRAVTVMVAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FMCITLLIASLICLTLPVFAGRWLMSFWTGTAKIHELYTAACGLYVCWLTIRAVTVMVAW
580 590 600 610 620 630
700 710 720 730 740 750
pF1KA0 MPQGRRVIFQKVKEWSLMIMKTLIVAVLLAGVVPLLLGLLFELVIVAPLRVPLDQTPLFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPQGRRVIFQKVKEWSLMIMKTLIVAVLLAGVVPLLLGLLFELVIVAPLRVPLDQTPLFY
640 650 660 670 680 690
760 770 780 790 800 810
pF1KA0 PWQDWALGVLHAKIIAAITLMGPQWWLKTVIEQVYANGIRNIDLHYIVRKLAAPVISVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PWQDWALGVLHAKIIAAITLMGPQWWLKTVIEQVYANGIRNIDLHYIVRKLAAPVISVLL
700 710 720 730 740 750
820 830 840 850 860 870
pF1KA0 LSLCVPYVIASGVVPLLGVTAEMQNLVHRRIYPFLLMVVVLMAILSFQVRQFKRLYEHIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSLCVPYVIASGVVPLLGVTAEMQNLVHRRIYPFLLMVVVLMAILSFQVRQFKRLYEHIK
760 770 780 790 800 810
880 890 900 910
pF1KA0 NDKYLVGQRLVNYERKSGKQGSSPPPPQSSQE
::::::::::::::::::::::::::::::::
XP_011 NDKYLVGQRLVNYERKSGKQGSSPPPPQSSQE
820 830 840
>>NP_001257589 (OMIM: 613297) E3 ubiquitin-protein ligas (862 aa)
initn: 5373 init1: 5373 opt: 5380 Z-score: 4726.8 bits: 885.8 E(85289): 0
Smith-Waterman score: 5736; 94.6% identity (94.6% similar) in 910 aa overlap (1-910:1-862)
10 20 30 40 50 60
pF1KA0 MDTAEEDICRVCRSEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDTAEEDICRVCRSEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 FTPIYSPDMPSRLPIQDIFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFT
::: ::::::::
NP_001 FTP------------------------------------------------SRIYKCLFT
70
130 140 150 160 170 180
pF1KA0 GSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAA
80 90 100 110 120 130
190 200 210 220 230 240
pF1KA0 PPFNAAGHHQNEAPAGGNGAENVAADQPANPPAENAVVGENPDAQDDQAEEEEEDNEEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPFNAAGHHQNEAPAGGNGAENVAADQPANPPAENAVVGENPDAQDDQAEEEEEDNEEED
140 150 160 170 180 190
250 260 270 280 290 300
pF1KA0 DAGVEDAADANNGAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DAGVEDAADANNGAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLF
200 210 220 230 240 250
310 320 330 340 350 360
pF1KA0 ILVFAFCPYHIGHFSLVGLGFEEHVQASHFEGLITTIVGYILLAITLIICHGLATLVKFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILVFAFCPYHIGHFSLVGLGFEEHVQASHFEGLITTIVGYILLAITLIICHGLATLVKFH
260 270 280 290 300 310
370 380 390 400 410 420
pF1KA0 RSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTT
320 330 340 350 360 370
430 440 450 460 470 480
pF1KA0 MFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRF
380 390 400 410 420 430
490 500 510 520 530 540
pF1KA0 ILSVIVFGSIVLLMLWLPIRIIKSVLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILSVIVFGSIVLLMLWLPIRIIKSVLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALL
440 450 460 470 480 490
550 560 570 580 590 600
pF1KA0 EQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEENENSANQQVNNNQHARNNNAIPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEENENSANQQVNNNQHARNNNAIPVV
500 510 520 530 540 550
610 620 630 640 650 660
pF1KA0 GEGLHAAHQAILQQGGPVGFQPYRRPLNFPLRIFLLIVFMCITLLIASLICLTLPVFAGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEGLHAAHQAILQQGGPVGFQPYRRPLNFPLRIFLLIVFMCITLLIASLICLTLPVFAGR
560 570 580 590 600 610
670 680 690 700 710 720
pF1KA0 WLMSFWTGTAKIHELYTAACGLYVCWLTIRAVTVMVAWMPQGRRVIFQKVKEWSLMIMKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WLMSFWTGTAKIHELYTAACGLYVCWLTIRAVTVMVAWMPQGRRVIFQKVKEWSLMIMKT
620 630 640 650 660 670
730 740 750 760 770 780
pF1KA0 LIVAVLLAGVVPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIVAVLLAGVVPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMG
680 690 700 710 720 730
790 800 810 820 830 840
pF1KA0 PQWWLKTVIEQVYANGIRNIDLHYIVRKLAAPVISVLLLSLCVPYVIASGVVPLLGVTAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQWWLKTVIEQVYANGIRNIDLHYIVRKLAAPVISVLLLSLCVPYVIASGVVPLLGVTAE
740 750 760 770 780 790
850 860 870 880 890 900
pF1KA0 MQNLVHRRIYPFLLMVVVLMAILSFQVRQFKRLYEHIKNDKYLVGQRLVNYERKSGKQGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQNLVHRRIYPFLLMVVVLMAILSFQVRQFKRLYEHIKNDKYLVGQRLVNYERKSGKQGS
800 810 820 830 840 850
910
pF1KA0 SPPPPQSSQE
::::::::::
NP_001 SPPPPQSSQE
860
>>NP_001257590 (OMIM: 613297) E3 ubiquitin-protein ligas (805 aa)
initn: 5369 init1: 5369 opt: 5369 Z-score: 4717.5 bits: 884.0 E(85289): 0
Smith-Waterman score: 5369; 100.0% identity (100.0% similar) in 798 aa overlap (113-910:8-805)
90 100 110 120 130 140
pF1KA0 VTSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFTGSVSSLLTLPLDMLSTENLLAD
::::::::::::::::::::::::::::::
NP_001 MDTAEEGRIYKCLFTGSVSSLLTLPLDMLSTENLLAD
10 20 30
150 160 170 180 190 200
pF1KA0 CLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAAPPFNAAGHHQNEAPAGGNGAEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAAPPFNAAGHHQNEAPAGGNGAEN
40 50 60 70 80 90
210 220 230 240 250 260
pF1KA0 VAADQPANPPAENAVVGENPDAQDDQAEEEEEDNEEEDDAGVEDAADANNGAQDDMNWNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAADQPANPPAENAVVGENPDAQDDQAEEEEEDNEEEDDAGVEDAADANNGAQDDMNWNA
100 110 120 130 140 150
270 280 290 300 310 320
pF1KA0 LEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLFILVFAFCPYHIGHFSLVGLGFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLFILVFAFCPYHIGHFSLVGLGFE
160 170 180 190 200 210
330 340 350 360 370 380
pF1KA0 EHVQASHFEGLITTIVGYILLAITLIICHGLATLVKFHRSRRLLGVCYIVVKVSLLVVVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHVQASHFEGLITTIVGYILLAITLIICHGLATLVKFHRSRRLLGVCYIVVKVSLLVVVE
220 230 240 250 260 270
390 400 410 420 430 440
pF1KA0 IGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTTMFLHWLVGMVYVFYFASFILLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTTMFLHWLVGMVYVFYFASFILLL
280 290 300 310 320 330
450 460 470 480 490 500
pF1KA0 REVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVIVFGSIVLLMLWLPIRII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVIVFGSIVLLMLWLPIRII
340 350 360 370 380 390
510 520 530 540 550 560
pF1KA0 KSVLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLKGLVRAWTVTAGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSVLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLKGLVRAWTVTAGY
400 410 420 430 440 450
570 580 590 600 610 620
pF1KA0 LLDLHSYLLGDQEENENSANQQVNNNQHARNNNAIPVVGEGLHAAHQAILQQGGPVGFQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLDLHSYLLGDQEENENSANQQVNNNQHARNNNAIPVVGEGLHAAHQAILQQGGPVGFQP
460 470 480 490 500 510
630 640 650 660 670 680
pF1KA0 YRRPLNFPLRIFLLIVFMCITLLIASLICLTLPVFAGRWLMSFWTGTAKIHELYTAACGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YRRPLNFPLRIFLLIVFMCITLLIASLICLTLPVFAGRWLMSFWTGTAKIHELYTAACGL
520 530 540 550 560 570
690 700 710 720 730 740
pF1KA0 YVCWLTIRAVTVMVAWMPQGRRVIFQKVKEWSLMIMKTLIVAVLLAGVVPLLLGLLFELV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVCWLTIRAVTVMVAWMPQGRRVIFQKVKEWSLMIMKTLIVAVLLAGVVPLLLGLLFELV
580 590 600 610 620 630
750 760 770 780 790 800
pF1KA0 IVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLKTVIEQVYANGIRNIDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLKTVIEQVYANGIRNIDL
640 650 660 670 680 690
810 820 830 840 850 860
pF1KA0 HYIVRKLAAPVISVLLLSLCVPYVIASGVVPLLGVTAEMQNLVHRRIYPFLLMVVVLMAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HYIVRKLAAPVISVLLLSLCVPYVIASGVVPLLGVTAEMQNLVHRRIYPFLLMVVVLMAI
700 710 720 730 740 750
870 880 890 900 910
pF1KA0 LSFQVRQFKRLYEHIKNDKYLVGQRLVNYERKSGKQGSSPPPPQSSQE
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSFQVRQFKRLYEHIKNDKYLVGQRLVNYERKSGKQGSSPPPPQSSQE
760 770 780 790 800
>>XP_011512236 (OMIM: 613297) PREDICTED: E3 ubiquitin-pr (791 aa)
initn: 5213 init1: 5213 opt: 5213 Z-score: 4580.7 bits: 858.6 E(85289): 0
Smith-Waterman score: 5213; 99.3% identity (99.3% similar) in 769 aa overlap (1-769:1-769)
10 20 30 40 50 60
pF1KA0 MDTAEEDICRVCRSEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDTAEEDICRVCRSEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 FTPIYSPDMPSRLPIQDIFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTPIYSPDMPSRLPIQDIFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 PPFNAAGHHQNEAPAGGNGAENVAADQPANPPAENAVVGENPDAQDDQAEEEEEDNEEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPFNAAGHHQNEAPAGGNGAENVAADQPANPPAENAVVGENPDAQDDQAEEEEEDNEEED
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 DAGVEDAADANNGAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAGVEDAADANNGAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 ILVFAFCPYHIGHFSLVGLGFEEHVQASHFEGLITTIVGYILLAITLIICHGLATLVKFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILVFAFCPYHIGHFSLVGLGFEEHVQASHFEGLITTIVGYILLAITLIICHGLATLVKFH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 RSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 MFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 ILSVIVFGSIVLLMLWLPIRIIKSVLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILSVIVFGSIVLLMLWLPIRIIKSVLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 EQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEENENSANQQVNNNQHARNNNAIPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEENENSANQQVNNNQHARNNNAIPVV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 GEGLHAAHQAILQQGGPVGFQPYRRPLNFPLRIFLLIVFMCITLLIASLICLTLPVFAGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEGLHAAHQAILQQGGPVGFQPYRRPLNFPLRIFLLIVFMCITLLIASLICLTLPVFAGR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 WLMSFWTGTAKIHELYTAACGLYVCWLTIRAVTVMVAWMPQGRRVIFQKVKEWSLMIMKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WLMSFWTGTAKIHELYTAACGLYVCWLTIRAVTVMVAWMPQGRRVIFQKVKEWSLMIMKT
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 LIVAVLLAGVVPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMG
::::::::::::::::::::::::::::::::::::::::: : ::
XP_011 LIVAVLLAGVVPLLLGLLFELVIVAPLRVPLDQTPLFYPWQMENLHKLHLPENFYLSAFN
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 PQWWLKTVIEQVYANGIRNIDLHYIVRKLAAPVISVLLLSLCVPYVIASGVVPLLGVTAE
XP_011 GVPTPWIVSPR
790
>>XP_011512238 (OMIM: 613297) PREDICTED: E3 ubiquitin-pr (637 aa)
initn: 4341 init1: 4341 opt: 4341 Z-score: 3816.9 bits: 717.0 E(85289): 7.3e-206
Smith-Waterman score: 4341; 100.0% identity (100.0% similar) in 632 aa overlap (1-632:1-632)
10 20 30 40 50 60
pF1KA0 MDTAEEDICRVCRSEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDTAEEDICRVCRSEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 FTPIYSPDMPSRLPIQDIFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTPIYSPDMPSRLPIQDIFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 PPFNAAGHHQNEAPAGGNGAENVAADQPANPPAENAVVGENPDAQDDQAEEEEEDNEEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPFNAAGHHQNEAPAGGNGAENVAADQPANPPAENAVVGENPDAQDDQAEEEEEDNEEED
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 DAGVEDAADANNGAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAGVEDAADANNGAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 ILVFAFCPYHIGHFSLVGLGFEEHVQASHFEGLITTIVGYILLAITLIICHGLATLVKFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILVFAFCPYHIGHFSLVGLGFEEHVQASHFEGLITTIVGYILLAITLIICHGLATLVKFH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 RSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 MFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 ILSVIVFGSIVLLMLWLPIRIIKSVLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILSVIVFGSIVLLMLWLPIRIIKSVLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 EQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEENENSANQQVNNNQHARNNNAIPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEENENSANQQVNNNQHARNNNAIPVV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 GEGLHAAHQAILQQGGPVGFQPYRRPLNFPLRIFLLIVFMCITLLIASLICLTLPVFAGR
::::::::::::::::::::::::::::::::
XP_011 GEGLHAAHQAILQQGGPVGFQPYRRPLNFPLRTKKAF
610 620 630
670 680 690 700 710 720
pF1KA0 WLMSFWTGTAKIHELYTAACGLYVCWLTIRAVTVMVAWMPQGRRVIFQKVKEWSLMIMKT
>>XP_011512239 (OMIM: 613297) PREDICTED: E3 ubiquitin-pr (510 aa)
initn: 3398 init1: 3398 opt: 3398 Z-score: 2990.8 bits: 563.8 E(85289): 7.6e-160
Smith-Waterman score: 3398; 100.0% identity (100.0% similar) in 510 aa overlap (401-910:1-510)
380 390 400 410 420 430
pF1KA0 IVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTTMFLHWLVGMV
::::::::::::::::::::::::::::::
XP_011 MFDATLKDRELSFQSAPGTTMFLHWLVGMV
10 20 30
440 450 460 470 480 490
pF1KA0 YVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVIVFGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVIVFGSI
40 50 60 70 80 90
500 510 520 530 540 550
pF1KA0 VLLMLWLPIRIIKSVLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLLMLWLPIRIIKSVLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLK
100 110 120 130 140 150
560 570 580 590 600 610
pF1KA0 GLVRAWTVTAGYLLDLHSYLLGDQEENENSANQQVNNNQHARNNNAIPVVGEGLHAAHQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLVRAWTVTAGYLLDLHSYLLGDQEENENSANQQVNNNQHARNNNAIPVVGEGLHAAHQA
160 170 180 190 200 210
620 630 640 650 660 670
pF1KA0 ILQQGGPVGFQPYRRPLNFPLRIFLLIVFMCITLLIASLICLTLPVFAGRWLMSFWTGTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILQQGGPVGFQPYRRPLNFPLRIFLLIVFMCITLLIASLICLTLPVFAGRWLMSFWTGTA
220 230 240 250 260 270
680 690 700 710 720 730
pF1KA0 KIHELYTAACGLYVCWLTIRAVTVMVAWMPQGRRVIFQKVKEWSLMIMKTLIVAVLLAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIHELYTAACGLYVCWLTIRAVTVMVAWMPQGRRVIFQKVKEWSLMIMKTLIVAVLLAGV
280 290 300 310 320 330
740 750 760 770 780 790
pF1KA0 VPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLKTVIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLKTVIE
340 350 360 370 380 390
800 810 820 830 840 850
pF1KA0 QVYANGIRNIDLHYIVRKLAAPVISVLLLSLCVPYVIASGVVPLLGVTAEMQNLVHRRIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVYANGIRNIDLHYIVRKLAAPVISVLLLSLCVPYVIASGVVPLLGVTAEMQNLVHRRIY
400 410 420 430 440 450
860 870 880 890 900 910
pF1KA0 PFLLMVVVLMAILSFQVRQFKRLYEHIKNDKYLVGQRLVNYERKSGKQGSSPPPPQSSQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PFLLMVVVLMAILSFQVRQFKRLYEHIKNDKYLVGQRLVNYERKSGKQGSSPPPPQSSQE
460 470 480 490 500 510
>>XP_016864433 (OMIM: 613297) PREDICTED: E3 ubiquitin-pr (460 aa)
initn: 3075 init1: 3075 opt: 3075 Z-score: 2707.9 bits: 511.3 E(85289): 4.3e-144
Smith-Waterman score: 3075; 100.0% identity (100.0% similar) in 444 aa overlap (1-444:1-444)
10 20 30 40 50 60
pF1KA0 MDTAEEDICRVCRSEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDTAEEDICRVCRSEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 FTPIYSPDMPSRLPIQDIFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTPIYSPDMPSRLPIQDIFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 PPFNAAGHHQNEAPAGGNGAENVAADQPANPPAENAVVGENPDAQDDQAEEEEEDNEEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPFNAAGHHQNEAPAGGNGAENVAADQPANPPAENAVVGENPDAQDDQAEEEEEDNEEED
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 DAGVEDAADANNGAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DAGVEDAADANNGAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 ILVFAFCPYHIGHFSLVGLGFEEHVQASHFEGLITTIVGYILLAITLIICHGLATLVKFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILVFAFCPYHIGHFSLVGLGFEEHVQASHFEGLITTIVGYILLAITLIICHGLATLVKFH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 RSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 MFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRF
::::::::::::::::::::::::
XP_016 MFLHWLVGMVYVFYFASFILLLREPENEYSIENVGLHGDG
430 440 450 460
>>XP_011537797 (OMIM: 613335) PREDICTED: E3 ubiquitin-pr (291 aa)
initn: 255 init1: 255 opt: 260 Z-score: 240.7 bits: 54.1 E(85289): 1.1e-06
Smith-Waterman score: 260; 51.6% identity (72.6% similar) in 62 aa overlap (6-67:77-138)
10 20 30
pF1KA0 MDTAEEDICRVCRSEGTPEKPLYHPCVCTGSIKFI
.::::.:. :: :.:: :: ::::..:.
XP_011 SNISKAGSPPSASAPAPVSSFSRTSITPSSQDICRICHCEGDDESPLITPCHCTGSLHFV
50 60 70 80 90 100
40 50 60 70 80 90
pF1KA0 HQECLVQWLKHSRKEYCELCKHRFAFTPIYSPDMPSRLPIQDIFAGLVTSIGTAIRYWFH
:: :: ::.: : . :::::..: . .:
XP_011 HQACLQQWIKSSDTRCCELCKYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAI
110 120 130 140 150 160
100 110 120 130 140 150
pF1KA0 YTLVAFAWLGVVPLTACRIYKCLFTGSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLC
XP_011 TCVVWSLYVLIDRTAEEIKQGQATGILEWPFWTKLVVVAIGFTGGLLFMYVQCKVYVQLW
170 180 190 200 210 220
>>NP_001002266 (OMIM: 613335) E3 ubiquitin-protein ligas (291 aa)
initn: 255 init1: 255 opt: 260 Z-score: 240.7 bits: 54.1 E(85289): 1.1e-06
Smith-Waterman score: 260; 51.6% identity (72.6% similar) in 62 aa overlap (6-67:77-138)
10 20 30
pF1KA0 MDTAEEDICRVCRSEGTPEKPLYHPCVCTGSIKFI
.::::.:. :: :.:: :: ::::..:.
NP_001 SNISKAGSPPSASAPAPVSSFSRTSITPSSQDICRICHCEGDDESPLITPCHCTGSLHFV
50 60 70 80 90 100
40 50 60 70 80 90
pF1KA0 HQECLVQWLKHSRKEYCELCKHRFAFTPIYSPDMPSRLPIQDIFAGLVTSIGTAIRYWFH
:: :: ::.: : . :::::..: . .:
NP_001 HQACLQQWIKSSDTRCCELCKYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAI
110 120 130 140 150 160
100 110 120 130 140 150
pF1KA0 YTLVAFAWLGVVPLTACRIYKCLFTGSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLC
NP_001 TCVVWSLYVLIDRTAEEIKQGQATGILEWPFWTKLVVVAIGFTGGLLFMYVQCKVYVQLW
170 180 190 200 210 220
910 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 09:50:15 2016 done: Thu Nov 3 09:50:17 2016
Total Scan time: 14.170 Total Display time: 0.220
Function used was FASTA [36.3.4 Apr, 2011]