Result of FASTA (omim) for
pF1KA0581
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0581, 1216 aa
1>>>pF1KA0581 1216 - 1216 aa - 1216 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.6902+/-0.000617; mu= -1.4546+/- 0.038
mean_var=397.0296+/-81.510, 0's: 0 Z-trim(117.1): 141 B-trim: 985 in 1/52
Lambda= 0.064367
statistics sampled from 28749 (28892) to 28749 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.656), E-opt: 0.2 (0.339), width: 16
Scan time: 15.200
The best scores are: opt bits E(85289)
NP_056007 (OMIM: 607120,613722) 1-phosphatidylinos (1216) 7962 755.3 5.3e-217
XP_011527501 (OMIM: 607120,613722) PREDICTED: 1-ph (1153) 7478 710.4 1.7e-203
XP_016883241 (OMIM: 607120,613722) PREDICTED: 1-ph (1143) 7470 709.6 2.9e-203
NP_877398 (OMIM: 607120,613722) 1-phosphatidylinos (1173) 7469 709.5 3.1e-203
XP_011527502 (OMIM: 607120,613722) PREDICTED: 1-ph (1144) 7398 702.9 2.9e-201
XP_016883242 (OMIM: 607120,613722) PREDICTED: 1-ph (1115) 7273 691.3 9e-198
XP_011527503 (OMIM: 607120,613722) PREDICTED: 1-ph (1115) 7273 691.3 9e-198
XP_011527505 (OMIM: 607120,613722) PREDICTED: 1-ph ( 625) 4062 392.9 3.5e-108
NP_001271226 (OMIM: 604114) 1-phosphatidylinositol (1181) 3238 316.6 5.9e-85
XP_016877805 (OMIM: 604114) PREDICTED: 1-phosphati (1201) 2282 227.9 3.1e-58
XP_016877806 (OMIM: 604114) PREDICTED: 1-phosphati (1198) 2263 226.1 1.1e-57
XP_016877803 (OMIM: 604114) PREDICTED: 1-phosphati (1205) 2253 225.2 2e-57
XP_016873414 (OMIM: 600230) PREDICTED: 1-phosphati ( 703) 2218 221.7 1.3e-56
XP_011543403 (OMIM: 600230) PREDICTED: 1-phosphati (1154) 2218 221.9 1.9e-56
NP_000923 (OMIM: 600230) 1-phosphatidylinositol 4, (1234) 2218 221.9 2e-56
NP_001303243 (OMIM: 600230) 1-phosphatidylinositol (1234) 2218 221.9 2e-56
XP_016877808 (OMIM: 604114) PREDICTED: 1-phosphati (1136) 2217 221.8 2e-56
XP_016877804 (OMIM: 604114) PREDICTED: 1-phosphati (1204) 2142 214.9 2.6e-54
NP_004564 (OMIM: 604114) 1-phosphatidylinositol 4, (1185) 1951 197.1 5.6e-49
XP_011519976 (OMIM: 604114) PREDICTED: 1-phosphati (1192) 1930 195.2 2.2e-48
NP_001271227 (OMIM: 604114) 1-phosphatidylinositol (1170) 1927 194.9 2.6e-48
XP_016877807 (OMIM: 604114) PREDICTED: 1-phosphati (1190) 1927 194.9 2.6e-48
NP_001171812 (OMIM: 600230) 1-phosphatidylinositol (1167) 1847 187.5 4.5e-46
XP_016883370 (OMIM: 600810,614669) PREDICTED: 1-ph (1175) 1436 149.3 1.4e-34
NP_877949 (OMIM: 600810,614669) 1-phosphatidylinos (1175) 1436 149.3 1.4e-34
NP_001166117 (OMIM: 600810,614669) 1-phosphatidyli (1187) 1436 149.3 1.4e-34
XP_016883375 (OMIM: 600810,614669) PREDICTED: 1-ph ( 926) 1416 147.3 4.2e-34
XP_005260785 (OMIM: 600810,614669) PREDICTED: 1-ph ( 938) 1416 147.3 4.3e-34
XP_011527556 (OMIM: 600810,614669) PREDICTED: 1-ph (1046) 1416 147.4 4.6e-34
XP_016883373 (OMIM: 600810,614669) PREDICTED: 1-ph (1093) 1416 147.4 4.8e-34
XP_016883374 (OMIM: 600810,614669) PREDICTED: 1-ph (1093) 1416 147.4 4.8e-34
XP_016883372 (OMIM: 600810,614669) PREDICTED: 1-ph (1141) 1416 147.4 4.9e-34
XP_016883371 (OMIM: 600810,614669) PREDICTED: 1-ph (1153) 1416 147.4 4.9e-34
XP_016883369 (OMIM: 600810,614669) PREDICTED: 1-ph (1194) 1416 147.5 5.1e-34
NP_000924 (OMIM: 600810,614669) 1-phosphatidylinos (1194) 1416 147.5 5.1e-34
XP_006723631 (OMIM: 600810,614669) PREDICTED: 1-ph (1206) 1416 147.5 5.1e-34
XP_006723632 (OMIM: 600810,614669) PREDICTED: 1-ph (1206) 1416 147.5 5.1e-34
XP_005260781 (OMIM: 600810,614669) PREDICTED: 1-ph (1206) 1416 147.5 5.1e-34
XP_016859829 (OMIM: 600597) PREDICTED: inactive ph ( 997) 644 75.7 1.7e-12
XP_016859828 (OMIM: 600597) PREDICTED: inactive ph (1016) 644 75.7 1.7e-12
XP_005246701 (OMIM: 600597) PREDICTED: inactive ph (1016) 644 75.7 1.7e-12
XP_011509653 (OMIM: 600597) PREDICTED: inactive ph (1016) 644 75.7 1.7e-12
XP_005246700 (OMIM: 600597) PREDICTED: inactive ph (1021) 644 75.7 1.7e-12
NP_006217 (OMIM: 600597) inactive phospholipase C- (1095) 644 75.7 1.8e-12
XP_011538152 (OMIM: 608414,610725) PREDICTED: 1-ph (1931) 650 76.5 1.8e-12
XP_006717953 (OMIM: 608414,610725) PREDICTED: 1-ph (2008) 650 76.6 1.9e-12
XP_006717952 (OMIM: 608414,610725) PREDICTED: 1-ph (2300) 650 76.6 2.1e-12
XP_006717948 (OMIM: 608414,610725) PREDICTED: 1-ph (2316) 650 76.6 2.1e-12
XP_016871800 (OMIM: 608414,610725) PREDICTED: 1-ph (2316) 650 76.6 2.1e-12
XP_016871799 (OMIM: 608414,610725) PREDICTED: 1-ph (2316) 650 76.6 2.1e-12
>>NP_056007 (OMIM: 607120,613722) 1-phosphatidylinositol (1216 aa)
initn: 7962 init1: 7962 opt: 7962 Z-score: 4016.9 bits: 755.3 E(85289): 5.3e-217
Smith-Waterman score: 7962; 100.0% identity (100.0% similar) in 1216 aa overlap (1-1216:1-1216)
10 20 30 40 50 60
pF1KA0 MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 TELLDLSLVKDARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TELLDLSLVKDARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 AFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 DRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 TVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 GEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 ELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 QAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 KLSEQASNTYSDSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KLSEQASNTYSDSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 SNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 GTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 HFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 HFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 NAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNER
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 NQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKK
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 EADPGETPSEAPSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EADPGETPSEAPSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 VLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 RRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 QEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKI
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 TEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 KLQVELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KLQVELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSS
1150 1160 1170 1180 1190 1200
1210
pF1KA0 EELGGDIPGKEFDTPL
::::::::::::::::
NP_056 EELGGDIPGKEFDTPL
1210
>>XP_011527501 (OMIM: 607120,613722) PREDICTED: 1-phosph (1153 aa)
initn: 7578 init1: 7478 opt: 7478 Z-score: 3774.3 bits: 710.4 E(85289): 1.7e-203
Smith-Waterman score: 7478; 99.9% identity (100.0% similar) in 1143 aa overlap (1-1143:1-1143)
10 20 30 40 50 60
pF1KA0 MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 TELLDLSLVKDARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TELLDLSLVKDARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 AFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 DRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 TVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 GEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 ELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 QAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 KLSEQASNTYSDSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLSEQASNTYSDSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 SNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 GTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 HFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 NAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNER
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 NQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKK
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 EADPGETPSEAPSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EADPGETPSEAPSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 VLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 RRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 QEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKI
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 TEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 KLQVELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSS
:.:
XP_011 KIQTVNSVMRWLP
1150
>>XP_016883241 (OMIM: 607120,613722) PREDICTED: 1-phosph (1143 aa)
initn: 7570 init1: 7470 opt: 7470 Z-score: 3770.3 bits: 709.6 E(85289): 2.9e-203
Smith-Waterman score: 7470; 99.9% identity (100.0% similar) in 1142 aa overlap (1-1142:1-1142)
10 20 30 40 50 60
pF1KA0 MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 TELLDLSLVKDARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TELLDLSLVKDARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 AFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 DRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 TVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 GEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 ELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 QAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 KLSEQASNTYSDSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLSEQASNTYSDSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 SNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 GTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 HFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 NAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNER
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 NQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKK
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 EADPGETPSEAPSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EADPGETPSEAPSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 VLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 RRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 QEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKI
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 TEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 KLQVELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSS
:.
XP_016 KVP
>>NP_877398 (OMIM: 607120,613722) 1-phosphatidylinositol (1173 aa)
initn: 7469 init1: 7469 opt: 7469 Z-score: 3769.7 bits: 709.5 E(85289): 3.1e-203
Smith-Waterman score: 7469; 100.0% identity (100.0% similar) in 1141 aa overlap (1-1141:1-1141)
10 20 30 40 50 60
pF1KA0 MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 TELLDLSLVKDARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 TELLDLSLVKDARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 AFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 AFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 DRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 DRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 TVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 TVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 GEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 GEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 ELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 ELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 QAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 QAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 KLSEQASNTYSDSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 KLSEQASNTYSDSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 SNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 SNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 GTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 GTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 HFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 HFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 NAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 NAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNER
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 NQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 NQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKK
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 EADPGETPSEAPSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 EADPGETPSEAPSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 VLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 VLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 RRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 RRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 QEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 QEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKI
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 TEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 TEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 KLQVELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSS
:
NP_877 KGEGSSSFLSETCHEDPSVSPNFTPPNPQALKW
1150 1160 1170
>>XP_011527502 (OMIM: 607120,613722) PREDICTED: 1-phosph (1144 aa)
initn: 7398 init1: 7398 opt: 7398 Z-score: 3734.2 bits: 702.9 E(85289): 2.9e-201
Smith-Waterman score: 7398; 100.0% identity (100.0% similar) in 1134 aa overlap (83-1216:11-1144)
60 70 80 90 100 110
pF1KA0 YWTDQNKETELLDLSLVKDARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLV
::::::::::::::::::::::::::::::
XP_011 MGALNSYNFLDPKLRELLDVGNIGRLEQRMITVVYGPDLV
10 20 30 40
120 130 140 150 160 170
pF1KA0 NISHLNLVAFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NISHLNLVAFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLK
50 60 70 80 90 100
180 190 200 210 220 230
pF1KA0 NIYRLFSADRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NIYRLFSADRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEF
110 120 130 140 150 160
240 250 260 270 280 290
pF1KA0 GAKSKPYLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAKSKPYLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISV
170 180 190 200 210 220
300 310 320 330 340 350
pF1KA0 DGFMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGFMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQV
230 240 250 260 270 280
360 370 380 390 400 410
pF1KA0 LLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFE
290 300 310 320 330 340
420 430 440 450 460 470
pF1KA0 NHVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NHVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHK
350 360 370 380 390 400
480 490 500 510 520 530
pF1KA0 SSEGSGKKKLSEQASNTYSDSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSEGSGKKKLSEQASNTYSDSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGS
410 420 430 440 450 460
540 550 560 570 580 590
pF1KA0 EAMATEEMSNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAMATEEMSNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKM
470 480 490 500 510 520
600 610 620 630 640 650
pF1KA0 QLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKP
530 540 550 560 570 580
660 670 680 690 700 710
pF1KA0 EFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKA
590 600 610 620 630 640
720 730 740 750 760 770
pF1KA0 FKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYH
650 660 670 680 690 700
780 790 800 810 820 830
pF1KA0 YICLRNERNQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YICLRNERNQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTL
710 720 730 740 750 760
840 850 860 870 880 890
pF1KA0 EDEEEVKKEADPGETPSEAPSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDEEEVKKEADPGETPSEAPSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPA
770 780 790 800 810 820
900 910 920 930 940 950
pF1KA0 KTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKY
830 840 850 860 870 880
960 970 980 990 1000 1010
pF1KA0 NEIQNDYLRRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NEIQNDYLRRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQ
890 900 910 920 930 940
1020 1030 1040 1050 1060 1070
pF1KA0 QQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKM
950 960 970 980 990 1000
1080 1090 1100 1110 1120 1130
pF1KA0 DKKRQEKITEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKKRQEKITEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIR
1010 1020 1030 1040 1050 1060
1140 1150 1160 1170 1180 1190
pF1KA0 QQILDEKPKLQVELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHGSAPLSLSSDPGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQILDEKPKLQVELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHGSAPLSLSSDPGK
1070 1080 1090 1100 1110 1120
1200 1210
pF1KA0 VNHKTPSSEELGGDIPGKEFDTPL
::::::::::::::::::::::::
XP_011 VNHKTPSSEELGGDIPGKEFDTPL
1130 1140
>>XP_016883242 (OMIM: 607120,613722) PREDICTED: 1-phosph (1115 aa)
initn: 7273 init1: 7273 opt: 7273 Z-score: 3671.6 bits: 691.3 E(85289): 9e-198
Smith-Waterman score: 7273; 100.0% identity (100.0% similar) in 1115 aa overlap (102-1216:1-1115)
80 90 100 110 120 130
pF1KA0 ARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLVAFQEEVAKEWT
::::::::::::::::::::::::::::::
XP_016 MITVVYGPDLVNISHLNLVAFQEEVAKEWT
10 20 30
140 150 160 170 180 190
pF1KA0 NEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADRKRVETALEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADRKRVETALEA
40 50 60 70 80 90
200 210 220 230 240 250
pF1KA0 CSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYLTVDQMMDFINL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYLTVDQMMDFINL
100 110 120 130 140 150
260 270 280 290 300 310
pF1KA0 KQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLSGEENGVVSPEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLSGEENGVVSPEK
160 170 180 190 200 210
320 330 340 350 360 370
pF1KA0 LDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAE
220 230 240 250 260 270
380 390 400 410 420 430
pF1KA0 EEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLI
280 290 300 310 320 330
440 450 460 470 480 490
pF1KA0 FGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKKKLSEQASNTYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKKKLSEQASNTYS
340 350 360 370 380 390
500 510 520 530 540 550
pF1KA0 DSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVK
400 410 420 430 440 450
560 570 580 590 600 610
pF1KA0 FESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMP
460 470 480 490 500 510
620 630 640 650 660 670
pF1KA0 QLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVD
520 530 540 550 560 570
680 690 700 710 720 730
pF1KA0 GIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEP
580 590 600 610 620 630
740 750 760 770 780 790
pF1KA0 IVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNERNQPLTLPAVFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNERNQPLTLPAVFV
640 650 660 670 680 690
800 810 820 830 840 850
pF1KA0 YIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGETPSEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGETPSEA
700 710 720 730 740 750
860 870 880 890 900 910
pF1KA0 PSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIE
760 770 780 790 800 810
920 930 940 950 960 970
pF1KA0 ELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYLRRRAALEKSAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYLRRRAALEKSAK
820 830 840 850 860 870
980 990 1000 1010 1020 1030
pF1KA0 KDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQK
880 890 900 910 920 930
1040 1050 1060 1070 1080 1090
pF1KA0 REHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQM
940 950 960 970 980 990
1100 1110 1120 1130 1140 1150
pF1KA0 EEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQVELEQEYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQVELEQEYQ
1000 1010 1020 1030 1040 1050
1160 1170 1180 1190 1200 1210
pF1KA0 DKFKRLPLEILEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSSEELGGDIPGKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKFKRLPLEILEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSSEELGGDIPGKE
1060 1070 1080 1090 1100 1110
pF1KA0 FDTPL
:::::
XP_016 FDTPL
>>XP_011527503 (OMIM: 607120,613722) PREDICTED: 1-phosph (1115 aa)
initn: 7273 init1: 7273 opt: 7273 Z-score: 3671.6 bits: 691.3 E(85289): 9e-198
Smith-Waterman score: 7273; 100.0% identity (100.0% similar) in 1115 aa overlap (102-1216:1-1115)
80 90 100 110 120 130
pF1KA0 ARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLVAFQEEVAKEWT
::::::::::::::::::::::::::::::
XP_011 MITVVYGPDLVNISHLNLVAFQEEVAKEWT
10 20 30
140 150 160 170 180 190
pF1KA0 NEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADRKRVETALEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADRKRVETALEA
40 50 60 70 80 90
200 210 220 230 240 250
pF1KA0 CSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYLTVDQMMDFINL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYLTVDQMMDFINL
100 110 120 130 140 150
260 270 280 290 300 310
pF1KA0 KQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLSGEENGVVSPEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLSGEENGVVSPEK
160 170 180 190 200 210
320 330 340 350 360 370
pF1KA0 LDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAE
220 230 240 250 260 270
380 390 400 410 420 430
pF1KA0 EEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLI
280 290 300 310 320 330
440 450 460 470 480 490
pF1KA0 FGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKKKLSEQASNTYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKKKLSEQASNTYS
340 350 360 370 380 390
500 510 520 530 540 550
pF1KA0 DSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVK
400 410 420 430 440 450
560 570 580 590 600 610
pF1KA0 FESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMP
460 470 480 490 500 510
620 630 640 650 660 670
pF1KA0 QLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVD
520 530 540 550 560 570
680 690 700 710 720 730
pF1KA0 GIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEP
580 590 600 610 620 630
740 750 760 770 780 790
pF1KA0 IVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNERNQPLTLPAVFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNERNQPLTLPAVFV
640 650 660 670 680 690
800 810 820 830 840 850
pF1KA0 YIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGETPSEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGETPSEA
700 710 720 730 740 750
860 870 880 890 900 910
pF1KA0 PSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIE
760 770 780 790 800 810
920 930 940 950 960 970
pF1KA0 ELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYLRRRAALEKSAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYLRRRAALEKSAK
820 830 840 850 860 870
980 990 1000 1010 1020 1030
pF1KA0 KDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQK
880 890 900 910 920 930
1040 1050 1060 1070 1080 1090
pF1KA0 REHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQM
940 950 960 970 980 990
1100 1110 1120 1130 1140 1150
pF1KA0 EEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQVELEQEYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQVELEQEYQ
1000 1010 1020 1030 1040 1050
1160 1170 1180 1190 1200 1210
pF1KA0 DKFKRLPLEILEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSSEELGGDIPGKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKFKRLPLEILEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSSEELGGDIPGKE
1060 1070 1080 1090 1100 1110
pF1KA0 FDTPL
:::::
XP_011 FDTPL
>>XP_011527505 (OMIM: 607120,613722) PREDICTED: 1-phosph (625 aa)
initn: 4062 init1: 4062 opt: 4062 Z-score: 2063.2 bits: 392.9 E(85289): 3.5e-108
Smith-Waterman score: 4062; 100.0% identity (100.0% similar) in 625 aa overlap (592-1216:1-625)
570 580 590 600 610 620
pF1KA0 NKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQM
::::::::::::::::::::::::::::::
XP_011 MQLSRIYPKGTRVDSSNYMPQLFWNAGCQM
10 20 30
630 640 650 660 670 680
pF1KA0 VALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVK
40 50 60 70 80 90
690 700 710 720 730 740
pF1KA0 IISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPT
100 110 120 130 140 150
750 760 770 780 790 800
pF1KA0 LACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNERNQPLTLPAVFVYIEVKDYVPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNERNQPLTLPAVFVYIEVKDYVPD
160 170 180 190 200 210
810 820 830 840 850 860
pF1KA0 TYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGETPSEAPSEARTTPAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGETPSEAPSEARTTPAE
220 230 240 250 260 270
870 880 890 900 910 920
pF1KA0 NGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVK
280 290 300 310 320 330
930 940 950 960 970 980
pF1KA0 LQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYLRRRAALEKSAKKDSKKKSEPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYLRRRAALEKSAKKDSKKKSEPS
340 350 360 370 380 390
990 1000 1010 1020 1030 1040
pF1KA0 SPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQK
400 410 420 430 440 450
1050 1060 1070 1080 1090 1100
pF1KA0 LTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQMEEEKTEMIRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQMEEEKTEMIRS
460 470 480 490 500 510
1110 1120 1130 1140 1150 1160
pF1KA0 YIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQVELEQEYQDKFKRLPLEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQVELEQEYQDKFKRLPLEI
520 530 540 550 560 570
1170 1180 1190 1200 1210
pF1KA0 LEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSSEELGGDIPGKEFDTPL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSSEELGGDIPGKEFDTPL
580 590 600 610 620
>>NP_001271226 (OMIM: 604114) 1-phosphatidylinositol 4,5 (1181 aa)
initn: 3658 init1: 1618 opt: 3238 Z-score: 1646.3 bits: 316.6 E(85289): 5.9e-85
Smith-Waterman score: 3622; 48.6% identity (74.9% similar) in 1178 aa overlap (13-1170:8-1143)
10 20 30 40 50 60
pF1KA0 MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKE
: : :. :..: .:.::::..:...:.:::.::.:...::: :.::
NP_001 MSLLNPVLLPPKVKAYLSQGERFIKWDDETTVASPVILRVDPKGYYLYWTYQSKE
10 20 30 40 50
70 80 90 100 110
pF1KA0 TELLDLSLVKDARCGRHAKAPKDPKLREL--LDVGNIGRLEQRMITVVYGPDLVNISHLN
:.::.. ..:.: :. :: ::. :::.. .: . . : . .::: :::.:... :
NP_001 MEFLDITSIRDTRFGKFAKMPKSQKLRDVFNMDFPDNSFL-LKTLTVVSGPDMVDLTFHN
60 70 80 90 100 110
120 130 140 150 160 170
pF1KA0 LVAFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLF
.:...:.:.: :...:..:. . :. : ::..::.: .:::.:.. ::.::.::....:
NP_001 FVSYKENVGKAWAEDVLALVKHPLTANASRSTFLDKILVKLKMQLNSEGKIPVKNFFQMF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KA0 SADRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKP
:::::::.:: :: ::...::.: ::: ::. :: .::::::::.::. . ::.::
NP_001 PADRKRVEAALSACHLPKGKNDAINPEDFPEPVYKSFLMSLCPRPEIDEIFTSYHAKAKP
180 190 200 210 220 230
240 250 260 270 280 290
pF1KA0 YLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRY
:.: ... ::: :::: ::: .:.:: . .::: ::.::::.. :..::.: .:.. .
NP_001 YMTKEHLTKFINQKQRDSRLNSLLFPPARPDQVQGLIDKYEPSGINAQRGQLSPEGMVWF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KA0 LSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCR
: : ::.:.. .:: :..::.:::.::::::::::::::::..: ::.::::::::::::
NP_001 LCGPENSVLAQDKLLLHHDMTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLSGCR
300 310 320 330 340 350
360 370 380 390 400 410
pF1KA0 CVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSP
:::::::::. .:::.:::::::::.: :::.:::::: ::::::.::.::::::::::
NP_001 CVELDCWKGKPPDEEPIITHGFTMTTDIFFKEAIEAIAESAFKTSPYPIILSFENHVDSP
360 370 380 390 400 410
420 430 440 450 460 470
pF1KA0 KQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSG
.:::::::::: :::: :: :::::.::. ::::::: :: :::.::::.. .. .:.
NP_001 RQQAKMAEYCRTIFGDMLLTEPLEKFPLKPGVPLPSPEDLRGKILIKNKKNQFSGPTSSS
420 430 440 450 460 470
480 490 500 510 520
pF1KA0 KKKLSEQASNTYSDSSSMFEPSSPG--AGEADTESDDDD------------DDDDCKKSS
: .: ...:: ::.:. ::: :: .... :... :: .
NP_001 KDTGGE------AEGSS--PPSAPAVWAGEEGTELEEEEVEEEEEEESGNLDEEEIKKMQ
480 490 500 510 520
530 540 550 560 570 580
pF1KA0 MDEGTAGSEAMATEEMSNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPV
:::::: :. : ::::.:::::::.:: :::.: ..:.:. .:::.: :. . :.:. :
NP_001 SDEGTAGLEVTAYEEMSSLVNYIQPTKFVSFEFSAQKNRSYVISSFTELKAYDLLSKASV
530 540 550 560 570 580
590 600 610 620 630 640
pF1KA0 EFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNG
.::.::: :.:::::::::.::::::::.:::::::::::::::::: :: ::...:.::
NP_001 QFVDYNKRQMSRIYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMAVFEFNG
590 600 610 620 630 640
650 660 670 680 690 700
pF1KA0 KSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGL
.::: :: ::::::::.:.::. .: .::.:::. .:::::::...: :::::..:::
NP_001 QSGYLLKHEFMRRPDKQFNPFSVDRIDVVVATTLSITVISGQFLSERSVRTYVEVELFGL
650 660 670 680 690 700
710 720 730 740 750 760
pF1KA0 PVDTRRKAFKTKTSQG-NAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILP
: : .:. ..:: : . :..::::.:::.::.:...: :: ::.::.:::.::.::::.:
NP_001 PGDPKRR-YRTKLSPSTNSINPVWKEEPFVFEKILMPELASLRVAVMEEGNKFLGHRIIP
710 720 730 740 750 760
770 780 790 800 810 820
pF1KA0 VQAIRPGYHYICLRNERNQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQR
..:. :::..::..: :.:::.::.:...:.:::.: ..::. ::.:::..
NP_001 INALNSGYHHLCLHSESNMPLTMPALFIFLEMKDYIPGAWADLTVALANPIKF-------
770 780 790 800 810
830 840 850 860 870 880
pF1KA0 AKQLAALTLEDEEEVKKEADPGETPSEAPSEARTTPAENGVNHTTTLTPKPPSQALHSQP
.. .: . :: . : : : : ..:. . :: . :.: :.
NP_001 ------FSAHDTKSVKLKEAMGGLP-EKPFPL-ASPVASQVNGA--LAPT-------SNG
820 830 840 850 860
890 900 910 920 930 940
pF1KA0 APGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTD
.: ...: :. : . .. .: .. ..:::.. :. ::::..: ::...: .: .. .
NP_001 SP-AARAGAREEAMKEA--AEPRTASLEELRELKGVVKLQRRHEKELRELERRGARRWEE
870 880 890 900 910
950 960 970 980 990 1000
pF1KA0 LIKEHTTKYNEIQNDYLRRRAALEKSAKKDSKKK-SEPSSPDHGSSTIEQDLAALDAEMT
:... ... :. . .: . . : :.:: : : . :.. : ..:...
NP_001 LLQRGAAQLAELGPPGVGGVGACKLGPGKGSRKKRSLPREESAGAAPGEGP-EGVDGRVR
920 930 940 950 960 970
1010 1020 1030 1040 1050 1060
pF1KA0 QKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICE
.:::. . .:: .::: .:..:. :.:. ..:.: : .:: ::: :
NP_001 ----ELKDRLELELLRQGEEQYECVLKRKEQHVAEQISKMMELAREKQAAELKALKETSE
980 990 1000 1010 1020 1030
1070 1080 1090 1100 1110 1120
pF1KA0 KEKKELKKKMDKKRQEKITEAK--SKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKR
.. ::.:::.. :: :.: . :: .:. : :. :.:::::: ::.. : ..
NP_001 NDTKEMKKKLETKRLERIQGMTKVTTDKMAQERLKREINNSHIQEVVQVIKQMTENLERH
1040 1050 1060 1070 1080 1090
1130 1140 1150 1160 1170 1180
pF1KA0 QEKLVEKHKEIRQQILDEKPKLQVELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHG
:::: ::. .:: . . ..: : ::. ..: : :. : :. ..
NP_001 QEKLEEKQAACLEQIREMEKQFQKEALAEYEARMKGLEAEVKESVRACLRTCFPSEAKDK
1100 1110 1120 1130 1140 1150
1190 1200 1210
pF1KA0 SAPLSLSSDPGKVNHKTPSSEELGGDIPGKEFDTPL
NP_001 PERACECPPELCEQDPLIAKADAQESRL
1160 1170 1180
>>XP_016877805 (OMIM: 604114) PREDICTED: 1-phosphatidyli (1201 aa)
initn: 3327 init1: 1618 opt: 2282 Z-score: 1166.4 bits: 227.9 E(85289): 3.1e-58
Smith-Waterman score: 3581; 48.1% identity (73.9% similar) in 1198 aa overlap (13-1170:8-1163)
10 20 30 40 50 60
pF1KA0 MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKE
: : :. :..: .:.::::..:...:.:::.::.:...::: :.::
XP_016 MSLLNPVLLPPKVKAYLSQGERFIKWDDETTVASPVILRVDPKGYYLYWTYQSKE
10 20 30 40 50
70 80 90 100 110
pF1KA0 TELLDLSLVKDARCGRHAKAPKDPKLREL--LDVGNIGRLEQRMITVVYGPDLVNISHLN
:.::.. ..:.: :. :: ::. :::.. .: . . : . .::: :::.:... :
XP_016 MEFLDITSIRDTRFGKFAKMPKSQKLRDVFNMDFPDNSFL-LKTLTVVSGPDMVDLTFHN
60 70 80 90 100 110
120 130 140 150 160 170
pF1KA0 LVAFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLF
.:...:.:.: :...:..:. . :. : ::..::.: .:::.:.. ::.::.::....:
XP_016 FVSYKENVGKAWAEDVLALVKHPLTANASRSTFLDKILVKLKMQLNSEGKIPVKNFFQMF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KA0 SADRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKP
:::::::.:: :: ::...::.: ::: ::. :: .::::::::.::. . ::.::
XP_016 PADRKRVEAALSACHLPKGKNDAINPEDFPEPVYKSFLMSLCPRPEIDEIFTSYHAKAKP
180 190 200 210 220 230
240 250 260 270 280 290
pF1KA0 YLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRY
:.: ... ::: :::: ::: .:.:: . .::: ::.::::.. :..::.: .:.. .
XP_016 YMTKEHLTKFINQKQRDSRLNSLLFPPARPDQVQGLIDKYEPSGINAQRGQLSPEGMVWF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KA0 LSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCR
: : ::.:.. .:: :..::.:::.::::::::::::::::..: ::.::::::::::::
XP_016 LCGPENSVLAQDKLLLHHDMTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLSGCR
300 310 320 330 340 350
360 370 380 390 400 410
pF1KA0 CVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSP
:::::::::. .:::.:::::::::.: :::.:::::: ::::::.::.::::::::::
XP_016 CVELDCWKGKPPDEEPIITHGFTMTTDIFFKEAIEAIAESAFKTSPYPIILSFENHVDSP
360 370 380 390 400 410
420 430 440 450 460 470
pF1KA0 KQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSG
.:::::::::: :::: :: :::::.::. ::::::: :: :::.::::.. .. .:.
XP_016 RQQAKMAEYCRTIFGDMLLTEPLEKFPLKPGVPLPSPEDLRGKILIKNKKNQFSGPTSSS
420 430 440 450 460 470
480 490 500 510 520
pF1KA0 KKKLSEQASNTYSDSSSMFEPSSPG--AGEADTESDDDD------------DDDDCKKSS
: .: ...:: ::.:. ::: :: .... :... :: .
XP_016 KDTGGE------AEGSS--PPSAPAVWAGEEGTELEEEEVEEEEEEESGNLDEEEIKKMQ
480 490 500 510 520
530 540 550 560 570
pF1KA0 MDEGTAGSEAMATEEMSNLVNYIQPVKFESFEIS-------------KKRNKSFEMSSFV
:::::: :. : ::::.:::::::.:: :::.: .:.:.:. .:::.
XP_016 SDEGTAGLEVTAYEEMSSLVNYIQPTKFVSFEFSAPRLFTCIFSGHKHKKNRSYVISSFT
530 540 550 560 570 580
580 590 600 610 620 630
pF1KA0 ETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDL
: :. . :.:. :.::.::: :.:::::::::.::::::::.::::::::::::::::::
XP_016 ELKAYDLLSKASVQFVDYNKRQMSRIYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDL
590 600 610 620 630 640
640 650 660 670 680 690
pF1KA0 AMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDK
:: ::...:.::.::: :: ::::::::.:.::. .: .::.:::. .:::::::..
XP_016 PMQQNMAVFEFNGQSGYLLKHEFMRRPDKQFNPFSVDRIDVVVATTLSITVISGQFLSER
650 660 670 680 690 700
700 710 720 730 740 750
pF1KA0 KVGTYVEVDMFGLPVDTRRKAFKTKTSQG-NAVNPVWEEEPIVFKKVVLPTLACLRIAVY
.: :::::..:::: : .:. ..:: : . :..::::.:::.::.:...: :: ::.::.
XP_016 SVRTYVEVELFGLPGDPKRR-YRTKLSPSTNSINPVWKEEPFVFEKILMPELASLRVAVM
710 720 730 740 750 760
760 770 780 790 800 810
pF1KA0 EEGGKFIGHRILPVQAIRPGYHYICLRNERNQPLTLPAVFVYIEVKDYVPDTYADVIEAL
:::.::.::::.:..:. :::..::..: :.:::.::.:...:.:::.: ..::. ::
XP_016 EEGNKFLGHRIIPINALNSGYHHLCLHSESNMPLTMPALFIFLEMKDYIPGAWADLTVAL
770 780 790 800 810 820
820 830 840 850 860 870
pF1KA0 SNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGETPSEAPSEARTTPAENGVNHTTTL
.:::.. .. .: . :: . : : : : ..:. . :: . :
XP_016 ANPIKF-------------FSAHDTKSVKLKEAMGGLP-EKPFPL-ASPVASQVNGA--L
830 840 850 860
880 890 900 910 920 930
pF1KA0 TPKPPSQALHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEM
.: :. .: ...: :. : . .. .: .. ..:::.. :. ::::..: ::.
XP_016 APT-------SNGSP-AARAGAREEAMKEA--AEPRTASLEELRELKGVVKLQRRHEKEL
870 880 890 900 910
940 950 960 970 980
pF1KA0 KDLVKRHHKKTTDLIKEHTTKYNEIQNDYLRRRAALEKSAKKDSKKK-SEPSSPDHGSST
..: .: .. .:... ... :. . .: . . : :.:: : : . :..
XP_016 RELERRGARRWEELLQRGAAQLAELGPPGVGGVGACKLGPGKGSRKKRSLPREESAGAAP
920 930 940 950 960 970
990 1000 1010 1020 1030 1040
pF1KA0 IEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEEC
: ..:... .:::. . .:: .::: .:..:. :.:. ..:.:
XP_016 GEGP-EGVDGRVR----ELKDRLELELLRQGEEQYECVLKRKEQHVAEQISKMMELAREK
980 990 1000 1010 1020 1030
1050 1060 1070 1080 1090 1100
pF1KA0 QNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAK--SKDKSQMEEEKTEMIRSYIQEVV
: .:: ::: :.. ::.:::.. :: :.: . :: .:. : :. :.:::::
XP_016 QAAELKALKETSENDTKEMKKKLETKRLERIQGMTKVTTDKMAQERLKREINNSHIQEVV
1040 1050 1060 1070 1080 1090
1110 1120 1130 1140 1150 1160
pF1KA0 QYIKRLEEAQSKRQEKLVEKHKEIRQQILD-EK------PKLQVELEQEYQDKFKRLPLE
: ::.. : ..:::: ::. .:: . :: :..: : ::. ..: : :
XP_016 QVIKQMTENLERHQEKLEEKQAACLEQIREMEKQGSLLSPQFQKEALAEYEARMKGLEAE
1100 1110 1120 1130 1140 1150
1170 1180 1190 1200 1210
pF1KA0 ILEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSSEELGGDIPGKEFDTPL
. : :. ..
XP_016 VKESVRACLRTCFPSEAKDKPERACECPPELCEQDPLIAKADAQESRL
1160 1170 1180 1190 1200
1216 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 00:46:08 2016 done: Fri Nov 4 00:46:10 2016
Total Scan time: 15.200 Total Display time: 0.550
Function used was FASTA [36.3.4 Apr, 2011]