Result of FASTA (omim) for
pF1KA0569
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0569, 1214 aa
1>>>pF1KA0569 1214 - 1214 aa - 1214 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.3198+/-0.000524; mu= -4.1089+/- 0.033
mean_var=509.9157+/-110.270, 0's: 0 Z-trim(119.7): 1404 B-trim: 0 in 0/55
Lambda= 0.056797
statistics sampled from 32376 (34109) to 32376 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.717), E-opt: 0.2 (0.4), width: 16
Scan time: 14.360
The best scores are: opt bits E(85289)
XP_006712945 (OMIM: 235730,605802) PREDICTED: zinc (1214) 8206 688.8 5.6e-197
XP_006712944 (OMIM: 235730,605802) PREDICTED: zinc (1214) 8206 688.8 5.6e-197
NP_055610 (OMIM: 235730,605802) zinc finger E-box- (1214) 8206 688.8 5.6e-197
XP_011510534 (OMIM: 235730,605802) PREDICTED: zinc (1207) 8031 674.5 1.2e-192
XP_016860903 (OMIM: 235730,605802) PREDICTED: zinc (1102) 7437 625.7 4.9e-178
XP_016860904 (OMIM: 235730,605802) PREDICTED: zinc (1102) 7437 625.7 4.9e-178
NP_001165124 (OMIM: 235730,605802) zinc finger E-b (1190) 7315 615.8 5.3e-175
NP_001310580 (OMIM: 189909,609141,613270) zinc fin ( 906) 1071 104.0 4.6e-21
NP_001310591 (OMIM: 189909,609141,613270) zinc fin ( 906) 1071 104.0 4.6e-21
XP_016872092 (OMIM: 189909,609141,613270) PREDICTE ( 906) 1071 104.0 4.6e-21
NP_001310579 (OMIM: 189909,609141,613270) zinc fin ( 906) 1071 104.0 4.6e-21
XP_016872089 (OMIM: 189909,609141,613270) PREDICTE ( 906) 1071 104.0 4.6e-21
NP_001310583 (OMIM: 189909,609141,613270) zinc fin ( 906) 1071 104.0 4.6e-21
XP_016872087 (OMIM: 189909,609141,613270) PREDICTE ( 906) 1071 104.0 4.6e-21
XP_016872086 (OMIM: 189909,609141,613270) PREDICTE ( 906) 1071 104.0 4.6e-21
XP_011517945 (OMIM: 189909,609141,613270) PREDICTE ( 906) 1071 104.0 4.6e-21
NP_001310570 (OMIM: 189909,609141,613270) zinc fin ( 906) 1071 104.0 4.6e-21
NP_001310588 (OMIM: 189909,609141,613270) zinc fin ( 906) 1071 104.0 4.6e-21
NP_001310585 (OMIM: 189909,609141,613270) zinc fin ( 906) 1071 104.0 4.6e-21
NP_001310578 (OMIM: 189909,609141,613270) zinc fin ( 906) 1071 104.0 4.6e-21
NP_001310572 (OMIM: 189909,609141,613270) zinc fin ( 906) 1071 104.0 4.6e-21
NP_001310590 (OMIM: 189909,609141,613270) zinc fin ( 906) 1071 104.0 4.6e-21
NP_001310602 (OMIM: 189909,609141,613270) zinc fin ( 906) 1071 104.0 4.6e-21
NP_001310592 (OMIM: 189909,609141,613270) zinc fin ( 906) 1071 104.0 4.6e-21
NP_001310574 (OMIM: 189909,609141,613270) zinc fin ( 906) 1071 104.0 4.6e-21
NP_001310581 (OMIM: 189909,609141,613270) zinc fin ( 906) 1071 104.0 4.6e-21
NP_001310577 (OMIM: 189909,609141,613270) zinc fin ( 906) 1071 104.0 4.6e-21
NP_001310571 (OMIM: 189909,609141,613270) zinc fin ( 906) 1071 104.0 4.6e-21
NP_001310600 (OMIM: 189909,609141,613270) zinc fin ( 906) 1071 104.0 4.6e-21
NP_001310595 (OMIM: 189909,609141,613270) zinc fin ( 906) 1071 104.0 4.6e-21
NP_001310582 (OMIM: 189909,609141,613270) zinc fin ( 906) 1071 104.0 4.6e-21
XP_016872090 (OMIM: 189909,609141,613270) PREDICTE ( 906) 1071 104.0 4.6e-21
NP_001310573 (OMIM: 189909,609141,613270) zinc fin ( 906) 1071 104.0 4.6e-21
XP_016872088 (OMIM: 189909,609141,613270) PREDICTE ( 906) 1071 104.0 4.6e-21
NP_001310589 (OMIM: 189909,609141,613270) zinc fin ( 906) 1071 104.0 4.6e-21
NP_001310576 (OMIM: 189909,609141,613270) zinc fin ( 906) 1071 104.0 4.6e-21
NP_001310601 (OMIM: 189909,609141,613270) zinc fin ( 906) 1071 104.0 4.6e-21
NP_001310587 (OMIM: 189909,609141,613270) zinc fin ( 906) 1071 104.0 4.6e-21
XP_006717561 (OMIM: 189909,609141,613270) PREDICTE ( 906) 1071 104.0 4.6e-21
NP_001310584 (OMIM: 189909,609141,613270) zinc fin ( 906) 1071 104.0 4.6e-21
NP_001310594 (OMIM: 189909,609141,613270) zinc fin ( 906) 1071 104.0 4.6e-21
XP_016872091 (OMIM: 189909,609141,613270) PREDICTE ( 906) 1071 104.0 4.6e-21
NP_001310575 (OMIM: 189909,609141,613270) zinc fin ( 906) 1071 104.0 4.6e-21
NP_001310567 (OMIM: 189909,609141,613270) zinc fin ( 906) 1071 104.0 4.6e-21
NP_001310593 (OMIM: 189909,609141,613270) zinc fin ( 906) 1071 104.0 4.6e-21
NP_001310586 (OMIM: 189909,609141,613270) zinc fin ( 906) 1071 104.0 4.6e-21
NP_001310607 (OMIM: 189909,609141,613270) zinc fin (1033) 1071 104.1 5e-21
NP_001310604 (OMIM: 189909,609141,613270) zinc fin (1036) 1071 104.1 5e-21
NP_001310603 (OMIM: 189909,609141,613270) zinc fin (1050) 1071 104.1 5.1e-21
NP_001167566 (OMIM: 189909,609141,613270) zinc fin (1057) 1071 104.1 5.1e-21
>>XP_006712945 (OMIM: 235730,605802) PREDICTED: zinc fin (1214 aa)
initn: 8206 init1: 8206 opt: 8206 Z-score: 3657.3 bits: 688.8 E(85289): 5.6e-197
Smith-Waterman score: 8206; 100.0% identity (100.0% similar) in 1214 aa overlap (1-1214:1-1214)
10 20 30 40 50 60
pF1KA0 MKQPIMADGPRCKRRKQANPRRKNVVNYDNVVDTGSETDEEDKLHIAEDDGIANPLDQET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MKQPIMADGPRCKRRKQANPRRKNVVNYDNVVDTGSETDEEDKLHIAEDDGIANPLDQET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 SPASVPNHESSPHVSQALLPREEEEDEIREGGVEHPWHNNEILQASVDGPEEMKEDYDTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SPASVPNHESSPHVSQALLPREEEEDEIREGGVEHPWHNNEILQASVDGPEEMKEDYDTM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GPEATIQTAINNGTVKNANCTSDFEEYFAKRKLEERDGHAVSIEEYLQRSDTAIIYPEAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GPEATIQTAINNGTVKNANCTSDFEEYFAKRKLEERDGHAVSIEEYLQRSDTAIIYPEAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 EELSRLGTPEANGQEENDLPPGTPDAFAQLLTCPYCDRGYKRLTSLKEHIKYRHEKNEEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EELSRLGTPEANGQEENDLPPGTPDAFAQLLTCPYCDRGYKRLTSLKEHIKYRHEKNEEN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 FSCPLCSYTFAYRTQLERHMVTHKPGTDQHQMLTQGAGNRKFKCTECGKAFKYKHHLKEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FSCPLCSYTFAYRTQLERHMVTHKPGTDQHQMLTQGAGNRKFKCTECGKAFKYKHHLKEH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCIGLISVNGRMRNNIKTGSSPNSVSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCIGLISVNGRMRNNIKTGSSPNSVSSS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 PTNSAITQLRNKLENGKPLSMSEQTGLLKIKTEPLDFNDYKVLMATHGFSGTSPFMNGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PTNSAITQLRNKLENGKPLSMSEQTGLLKIKTEPLDFNDYKVLMATHGFSGTSPFMNGGL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 GATSPLGVHPSAQSPMQHLGVGMEAPLLGFPTMNSNLSEVQKVLQIVDNTVSRQKMDCKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GATSPLGVHPSAQSPMQHLGVGMEAPLLGFPTMNSNLSEVQKVLQIVDNTVSRQKMDCKA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 EEISKLKGYHMKDPCSQPEEQGVTSPNIPPVGLPVVSHNGATKSIIDYTLEKVNEAKACL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EEISKLKGYHMKDPCSQPEEQGVTSPNIPPVGLPVVSHNGATKSIIDYTLEKVNEAKACL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 QSLTTDSRRQISNIKKEKLRTLIDLVTDDKMIENHNISTPFSCQFCKESFPGPIPLHQHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QSLTTDSRRQISNIKKEKLRTLIDLVTDDKMIENHNISTPFSCQFCKESFPGPIPLHQHE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 RYLCKMNEEIKAVLQPHENIVPNKAGVFVDNKALLLSSVLSEKGMTSPINPYKDHMSVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RYLCKMNEEIKAVLQPHENIVPNKAGVFVDNKALLLSSVLSEKGMTSPINPYKDHMSVLK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 AYYAMNMEPNSDELLKISIAVGLPQEFVKEWFEQRKVYQYSNSRSPSLERSSKPLAPNSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AYYAMNMEPNSDELLKISIAVGLPQEFVKEWFEQRKVYQYSNSRSPSLERSSKPLAPNSN
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 PPTKDSLLPRSPVKPMDSITSPSIAELHNSVTNCDPPLRLTKPSHFTNIKPVEKLDHSRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPTKDSLLPRSPVKPMDSITSPSIAELHNSVTNCDPPLRLTKPSHFTNIKPVEKLDHSRS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 NTPSPLNLSSTSSKNSHSSSYTPNSFSSEELQAEPLDLSLPKQMKEPKSIIATKNKTKAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NTPSPLNLSSTSSKNSHSSSYTPNSFSSEELQAEPLDLSLPKQMKEPKSIIATKNKTKAS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 SISLDHNSVSSSSENSDEPLNLTFIKKEFSNSNNLDNKSTNPVFSMNPFSAKPLYTALPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SISLDHNSVSSSSENSDEPLNLTFIKKEFSNSNNLDNKSTNPVFSMNPFSAKPLYTALPP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 QSAFPPATFMPPVQTSIPGLRPYPGLDQMSFLPHMAYTYPTGAATFADMQQRRKYQRKQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QSAFPPATFMPPVQTSIPGLRPYPGLDQMSFLPHMAYTYPTGAATFADMQQRRKYQRKQG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 FQGELLDGAQDYMSGLDDMTDSDSCLSRKKIKKTESGMYACDLCDKTFQKSSSLLRHKYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FQGELLDGAQDYMSGLDDMTDSDSCLSRKKIKKTESGMYACDLCDKTFQKSSSLLRHKYE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 HTGKRPHQCQICKKAFKHKHHLIEHSRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HTGKRPHQCQICKKAFKHKHHLIEHSRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSY
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 CKREAEEREAAEREAREKGHLEPTELLMNRAYLQSITPQGYSDSEERESMPRDGESEKEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CKREAEEREAAEREAREKGHLEPTELLMNRAYLQSITPQGYSDSEERESMPRDGESEKEH
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 EKEGEDGYGKLGRQDGDEEFEEEEEESENKSMDTDPETIRDEEETGDHSMDDSSEDGKME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EKEGEDGYGKLGRQDGDEEFEEEEEESENKSMDTDPETIRDEEETGDHSMDDSSEDGKME
1150 1160 1170 1180 1190 1200
1210
pF1KA0 TKSDHEEDNMEDGM
::::::::::::::
XP_006 TKSDHEEDNMEDGM
1210
>>XP_006712944 (OMIM: 235730,605802) PREDICTED: zinc fin (1214 aa)
initn: 8206 init1: 8206 opt: 8206 Z-score: 3657.3 bits: 688.8 E(85289): 5.6e-197
Smith-Waterman score: 8206; 100.0% identity (100.0% similar) in 1214 aa overlap (1-1214:1-1214)
10 20 30 40 50 60
pF1KA0 MKQPIMADGPRCKRRKQANPRRKNVVNYDNVVDTGSETDEEDKLHIAEDDGIANPLDQET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MKQPIMADGPRCKRRKQANPRRKNVVNYDNVVDTGSETDEEDKLHIAEDDGIANPLDQET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 SPASVPNHESSPHVSQALLPREEEEDEIREGGVEHPWHNNEILQASVDGPEEMKEDYDTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SPASVPNHESSPHVSQALLPREEEEDEIREGGVEHPWHNNEILQASVDGPEEMKEDYDTM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GPEATIQTAINNGTVKNANCTSDFEEYFAKRKLEERDGHAVSIEEYLQRSDTAIIYPEAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GPEATIQTAINNGTVKNANCTSDFEEYFAKRKLEERDGHAVSIEEYLQRSDTAIIYPEAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 EELSRLGTPEANGQEENDLPPGTPDAFAQLLTCPYCDRGYKRLTSLKEHIKYRHEKNEEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EELSRLGTPEANGQEENDLPPGTPDAFAQLLTCPYCDRGYKRLTSLKEHIKYRHEKNEEN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 FSCPLCSYTFAYRTQLERHMVTHKPGTDQHQMLTQGAGNRKFKCTECGKAFKYKHHLKEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FSCPLCSYTFAYRTQLERHMVTHKPGTDQHQMLTQGAGNRKFKCTECGKAFKYKHHLKEH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCIGLISVNGRMRNNIKTGSSPNSVSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCIGLISVNGRMRNNIKTGSSPNSVSSS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 PTNSAITQLRNKLENGKPLSMSEQTGLLKIKTEPLDFNDYKVLMATHGFSGTSPFMNGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PTNSAITQLRNKLENGKPLSMSEQTGLLKIKTEPLDFNDYKVLMATHGFSGTSPFMNGGL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 GATSPLGVHPSAQSPMQHLGVGMEAPLLGFPTMNSNLSEVQKVLQIVDNTVSRQKMDCKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GATSPLGVHPSAQSPMQHLGVGMEAPLLGFPTMNSNLSEVQKVLQIVDNTVSRQKMDCKA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 EEISKLKGYHMKDPCSQPEEQGVTSPNIPPVGLPVVSHNGATKSIIDYTLEKVNEAKACL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EEISKLKGYHMKDPCSQPEEQGVTSPNIPPVGLPVVSHNGATKSIIDYTLEKVNEAKACL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 QSLTTDSRRQISNIKKEKLRTLIDLVTDDKMIENHNISTPFSCQFCKESFPGPIPLHQHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QSLTTDSRRQISNIKKEKLRTLIDLVTDDKMIENHNISTPFSCQFCKESFPGPIPLHQHE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 RYLCKMNEEIKAVLQPHENIVPNKAGVFVDNKALLLSSVLSEKGMTSPINPYKDHMSVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RYLCKMNEEIKAVLQPHENIVPNKAGVFVDNKALLLSSVLSEKGMTSPINPYKDHMSVLK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 AYYAMNMEPNSDELLKISIAVGLPQEFVKEWFEQRKVYQYSNSRSPSLERSSKPLAPNSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AYYAMNMEPNSDELLKISIAVGLPQEFVKEWFEQRKVYQYSNSRSPSLERSSKPLAPNSN
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 PPTKDSLLPRSPVKPMDSITSPSIAELHNSVTNCDPPLRLTKPSHFTNIKPVEKLDHSRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPTKDSLLPRSPVKPMDSITSPSIAELHNSVTNCDPPLRLTKPSHFTNIKPVEKLDHSRS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 NTPSPLNLSSTSSKNSHSSSYTPNSFSSEELQAEPLDLSLPKQMKEPKSIIATKNKTKAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NTPSPLNLSSTSSKNSHSSSYTPNSFSSEELQAEPLDLSLPKQMKEPKSIIATKNKTKAS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 SISLDHNSVSSSSENSDEPLNLTFIKKEFSNSNNLDNKSTNPVFSMNPFSAKPLYTALPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SISLDHNSVSSSSENSDEPLNLTFIKKEFSNSNNLDNKSTNPVFSMNPFSAKPLYTALPP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 QSAFPPATFMPPVQTSIPGLRPYPGLDQMSFLPHMAYTYPTGAATFADMQQRRKYQRKQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QSAFPPATFMPPVQTSIPGLRPYPGLDQMSFLPHMAYTYPTGAATFADMQQRRKYQRKQG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 FQGELLDGAQDYMSGLDDMTDSDSCLSRKKIKKTESGMYACDLCDKTFQKSSSLLRHKYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FQGELLDGAQDYMSGLDDMTDSDSCLSRKKIKKTESGMYACDLCDKTFQKSSSLLRHKYE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 HTGKRPHQCQICKKAFKHKHHLIEHSRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HTGKRPHQCQICKKAFKHKHHLIEHSRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSY
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 CKREAEEREAAEREAREKGHLEPTELLMNRAYLQSITPQGYSDSEERESMPRDGESEKEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CKREAEEREAAEREAREKGHLEPTELLMNRAYLQSITPQGYSDSEERESMPRDGESEKEH
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 EKEGEDGYGKLGRQDGDEEFEEEEEESENKSMDTDPETIRDEEETGDHSMDDSSEDGKME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EKEGEDGYGKLGRQDGDEEFEEEEEESENKSMDTDPETIRDEEETGDHSMDDSSEDGKME
1150 1160 1170 1180 1190 1200
1210
pF1KA0 TKSDHEEDNMEDGM
::::::::::::::
XP_006 TKSDHEEDNMEDGM
1210
>>NP_055610 (OMIM: 235730,605802) zinc finger E-box-bind (1214 aa)
initn: 8206 init1: 8206 opt: 8206 Z-score: 3657.3 bits: 688.8 E(85289): 5.6e-197
Smith-Waterman score: 8206; 100.0% identity (100.0% similar) in 1214 aa overlap (1-1214:1-1214)
10 20 30 40 50 60
pF1KA0 MKQPIMADGPRCKRRKQANPRRKNVVNYDNVVDTGSETDEEDKLHIAEDDGIANPLDQET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MKQPIMADGPRCKRRKQANPRRKNVVNYDNVVDTGSETDEEDKLHIAEDDGIANPLDQET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 SPASVPNHESSPHVSQALLPREEEEDEIREGGVEHPWHNNEILQASVDGPEEMKEDYDTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SPASVPNHESSPHVSQALLPREEEEDEIREGGVEHPWHNNEILQASVDGPEEMKEDYDTM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GPEATIQTAINNGTVKNANCTSDFEEYFAKRKLEERDGHAVSIEEYLQRSDTAIIYPEAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GPEATIQTAINNGTVKNANCTSDFEEYFAKRKLEERDGHAVSIEEYLQRSDTAIIYPEAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 EELSRLGTPEANGQEENDLPPGTPDAFAQLLTCPYCDRGYKRLTSLKEHIKYRHEKNEEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EELSRLGTPEANGQEENDLPPGTPDAFAQLLTCPYCDRGYKRLTSLKEHIKYRHEKNEEN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 FSCPLCSYTFAYRTQLERHMVTHKPGTDQHQMLTQGAGNRKFKCTECGKAFKYKHHLKEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FSCPLCSYTFAYRTQLERHMVTHKPGTDQHQMLTQGAGNRKFKCTECGKAFKYKHHLKEH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCIGLISVNGRMRNNIKTGSSPNSVSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCIGLISVNGRMRNNIKTGSSPNSVSSS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 PTNSAITQLRNKLENGKPLSMSEQTGLLKIKTEPLDFNDYKVLMATHGFSGTSPFMNGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PTNSAITQLRNKLENGKPLSMSEQTGLLKIKTEPLDFNDYKVLMATHGFSGTSPFMNGGL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 GATSPLGVHPSAQSPMQHLGVGMEAPLLGFPTMNSNLSEVQKVLQIVDNTVSRQKMDCKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GATSPLGVHPSAQSPMQHLGVGMEAPLLGFPTMNSNLSEVQKVLQIVDNTVSRQKMDCKA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 EEISKLKGYHMKDPCSQPEEQGVTSPNIPPVGLPVVSHNGATKSIIDYTLEKVNEAKACL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EEISKLKGYHMKDPCSQPEEQGVTSPNIPPVGLPVVSHNGATKSIIDYTLEKVNEAKACL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 QSLTTDSRRQISNIKKEKLRTLIDLVTDDKMIENHNISTPFSCQFCKESFPGPIPLHQHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QSLTTDSRRQISNIKKEKLRTLIDLVTDDKMIENHNISTPFSCQFCKESFPGPIPLHQHE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 RYLCKMNEEIKAVLQPHENIVPNKAGVFVDNKALLLSSVLSEKGMTSPINPYKDHMSVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RYLCKMNEEIKAVLQPHENIVPNKAGVFVDNKALLLSSVLSEKGMTSPINPYKDHMSVLK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 AYYAMNMEPNSDELLKISIAVGLPQEFVKEWFEQRKVYQYSNSRSPSLERSSKPLAPNSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AYYAMNMEPNSDELLKISIAVGLPQEFVKEWFEQRKVYQYSNSRSPSLERSSKPLAPNSN
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 PPTKDSLLPRSPVKPMDSITSPSIAELHNSVTNCDPPLRLTKPSHFTNIKPVEKLDHSRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PPTKDSLLPRSPVKPMDSITSPSIAELHNSVTNCDPPLRLTKPSHFTNIKPVEKLDHSRS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 NTPSPLNLSSTSSKNSHSSSYTPNSFSSEELQAEPLDLSLPKQMKEPKSIIATKNKTKAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NTPSPLNLSSTSSKNSHSSSYTPNSFSSEELQAEPLDLSLPKQMKEPKSIIATKNKTKAS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 SISLDHNSVSSSSENSDEPLNLTFIKKEFSNSNNLDNKSTNPVFSMNPFSAKPLYTALPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SISLDHNSVSSSSENSDEPLNLTFIKKEFSNSNNLDNKSTNPVFSMNPFSAKPLYTALPP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 QSAFPPATFMPPVQTSIPGLRPYPGLDQMSFLPHMAYTYPTGAATFADMQQRRKYQRKQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QSAFPPATFMPPVQTSIPGLRPYPGLDQMSFLPHMAYTYPTGAATFADMQQRRKYQRKQG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 FQGELLDGAQDYMSGLDDMTDSDSCLSRKKIKKTESGMYACDLCDKTFQKSSSLLRHKYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FQGELLDGAQDYMSGLDDMTDSDSCLSRKKIKKTESGMYACDLCDKTFQKSSSLLRHKYE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 HTGKRPHQCQICKKAFKHKHHLIEHSRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 HTGKRPHQCQICKKAFKHKHHLIEHSRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSY
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 CKREAEEREAAEREAREKGHLEPTELLMNRAYLQSITPQGYSDSEERESMPRDGESEKEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CKREAEEREAAEREAREKGHLEPTELLMNRAYLQSITPQGYSDSEERESMPRDGESEKEH
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 EKEGEDGYGKLGRQDGDEEFEEEEEESENKSMDTDPETIRDEEETGDHSMDDSSEDGKME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EKEGEDGYGKLGRQDGDEEFEEEEEESENKSMDTDPETIRDEEETGDHSMDDSSEDGKME
1150 1160 1170 1180 1190 1200
1210
pF1KA0 TKSDHEEDNMEDGM
::::::::::::::
NP_055 TKSDHEEDNMEDGM
1210
>>XP_011510534 (OMIM: 235730,605802) PREDICTED: zinc fin (1207 aa)
initn: 8031 init1: 8031 opt: 8031 Z-score: 3579.9 bits: 674.5 E(85289): 1.2e-192
Smith-Waterman score: 8031; 100.0% identity (100.0% similar) in 1190 aa overlap (25-1214:18-1207)
10 20 30 40 50 60
pF1KA0 MKQPIMADGPRCKRRKQANPRRKNVVNYDNVVDTGSETDEEDKLHIAEDDGIANPLDQET
::::::::::::::::::::::::::::::::::::
XP_011 MLFLLTISGQNYKQDFAVVNYDNVVDTGSETDEEDKLHIAEDDGIANPLDQET
10 20 30 40 50
70 80 90 100 110 120
pF1KA0 SPASVPNHESSPHVSQALLPREEEEDEIREGGVEHPWHNNEILQASVDGPEEMKEDYDTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPASVPNHESSPHVSQALLPREEEEDEIREGGVEHPWHNNEILQASVDGPEEMKEDYDTM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KA0 GPEATIQTAINNGTVKNANCTSDFEEYFAKRKLEERDGHAVSIEEYLQRSDTAIIYPEAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPEATIQTAINNGTVKNANCTSDFEEYFAKRKLEERDGHAVSIEEYLQRSDTAIIYPEAP
120 130 140 150 160 170
190 200 210 220 230 240
pF1KA0 EELSRLGTPEANGQEENDLPPGTPDAFAQLLTCPYCDRGYKRLTSLKEHIKYRHEKNEEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EELSRLGTPEANGQEENDLPPGTPDAFAQLLTCPYCDRGYKRLTSLKEHIKYRHEKNEEN
180 190 200 210 220 230
250 260 270 280 290 300
pF1KA0 FSCPLCSYTFAYRTQLERHMVTHKPGTDQHQMLTQGAGNRKFKCTECGKAFKYKHHLKEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSCPLCSYTFAYRTQLERHMVTHKPGTDQHQMLTQGAGNRKFKCTECGKAFKYKHHLKEH
240 250 260 270 280 290
310 320 330 340 350 360
pF1KA0 LRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCIGLISVNGRMRNNIKTGSSPNSVSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCIGLISVNGRMRNNIKTGSSPNSVSSS
300 310 320 330 340 350
370 380 390 400 410 420
pF1KA0 PTNSAITQLRNKLENGKPLSMSEQTGLLKIKTEPLDFNDYKVLMATHGFSGTSPFMNGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTNSAITQLRNKLENGKPLSMSEQTGLLKIKTEPLDFNDYKVLMATHGFSGTSPFMNGGL
360 370 380 390 400 410
430 440 450 460 470 480
pF1KA0 GATSPLGVHPSAQSPMQHLGVGMEAPLLGFPTMNSNLSEVQKVLQIVDNTVSRQKMDCKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GATSPLGVHPSAQSPMQHLGVGMEAPLLGFPTMNSNLSEVQKVLQIVDNTVSRQKMDCKA
420 430 440 450 460 470
490 500 510 520 530 540
pF1KA0 EEISKLKGYHMKDPCSQPEEQGVTSPNIPPVGLPVVSHNGATKSIIDYTLEKVNEAKACL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEISKLKGYHMKDPCSQPEEQGVTSPNIPPVGLPVVSHNGATKSIIDYTLEKVNEAKACL
480 490 500 510 520 530
550 560 570 580 590 600
pF1KA0 QSLTTDSRRQISNIKKEKLRTLIDLVTDDKMIENHNISTPFSCQFCKESFPGPIPLHQHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSLTTDSRRQISNIKKEKLRTLIDLVTDDKMIENHNISTPFSCQFCKESFPGPIPLHQHE
540 550 560 570 580 590
610 620 630 640 650 660
pF1KA0 RYLCKMNEEIKAVLQPHENIVPNKAGVFVDNKALLLSSVLSEKGMTSPINPYKDHMSVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYLCKMNEEIKAVLQPHENIVPNKAGVFVDNKALLLSSVLSEKGMTSPINPYKDHMSVLK
600 610 620 630 640 650
670 680 690 700 710 720
pF1KA0 AYYAMNMEPNSDELLKISIAVGLPQEFVKEWFEQRKVYQYSNSRSPSLERSSKPLAPNSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AYYAMNMEPNSDELLKISIAVGLPQEFVKEWFEQRKVYQYSNSRSPSLERSSKPLAPNSN
660 670 680 690 700 710
730 740 750 760 770 780
pF1KA0 PPTKDSLLPRSPVKPMDSITSPSIAELHNSVTNCDPPLRLTKPSHFTNIKPVEKLDHSRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPTKDSLLPRSPVKPMDSITSPSIAELHNSVTNCDPPLRLTKPSHFTNIKPVEKLDHSRS
720 730 740 750 760 770
790 800 810 820 830 840
pF1KA0 NTPSPLNLSSTSSKNSHSSSYTPNSFSSEELQAEPLDLSLPKQMKEPKSIIATKNKTKAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTPSPLNLSSTSSKNSHSSSYTPNSFSSEELQAEPLDLSLPKQMKEPKSIIATKNKTKAS
780 790 800 810 820 830
850 860 870 880 890 900
pF1KA0 SISLDHNSVSSSSENSDEPLNLTFIKKEFSNSNNLDNKSTNPVFSMNPFSAKPLYTALPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SISLDHNSVSSSSENSDEPLNLTFIKKEFSNSNNLDNKSTNPVFSMNPFSAKPLYTALPP
840 850 860 870 880 890
910 920 930 940 950 960
pF1KA0 QSAFPPATFMPPVQTSIPGLRPYPGLDQMSFLPHMAYTYPTGAATFADMQQRRKYQRKQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSAFPPATFMPPVQTSIPGLRPYPGLDQMSFLPHMAYTYPTGAATFADMQQRRKYQRKQG
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KA0 FQGELLDGAQDYMSGLDDMTDSDSCLSRKKIKKTESGMYACDLCDKTFQKSSSLLRHKYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQGELLDGAQDYMSGLDDMTDSDSCLSRKKIKKTESGMYACDLCDKTFQKSSSLLRHKYE
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KA0 HTGKRPHQCQICKKAFKHKHHLIEHSRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HTGKRPHQCQICKKAFKHKHHLIEHSRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSY
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KA0 CKREAEEREAAEREAREKGHLEPTELLMNRAYLQSITPQGYSDSEERESMPRDGESEKEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CKREAEEREAAEREAREKGHLEPTELLMNRAYLQSITPQGYSDSEERESMPRDGESEKEH
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KA0 EKEGEDGYGKLGRQDGDEEFEEEEEESENKSMDTDPETIRDEEETGDHSMDDSSEDGKME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKEGEDGYGKLGRQDGDEEFEEEEEESENKSMDTDPETIRDEEETGDHSMDDSSEDGKME
1140 1150 1160 1170 1180 1190
1210
pF1KA0 TKSDHEEDNMEDGM
::::::::::::::
XP_011 TKSDHEEDNMEDGM
1200
>>XP_016860903 (OMIM: 235730,605802) PREDICTED: zinc fin (1102 aa)
initn: 7437 init1: 7437 opt: 7437 Z-score: 3317.3 bits: 625.7 E(85289): 4.9e-178
Smith-Waterman score: 7437; 100.0% identity (100.0% similar) in 1102 aa overlap (113-1214:1-1102)
90 100 110 120 130 140
pF1KA0 EEEDEIREGGVEHPWHNNEILQASVDGPEEMKEDYDTMGPEATIQTAINNGTVKNANCTS
::::::::::::::::::::::::::::::
XP_016 MKEDYDTMGPEATIQTAINNGTVKNANCTS
10 20 30
150 160 170 180 190 200
pF1KA0 DFEEYFAKRKLEERDGHAVSIEEYLQRSDTAIIYPEAPEELSRLGTPEANGQEENDLPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFEEYFAKRKLEERDGHAVSIEEYLQRSDTAIIYPEAPEELSRLGTPEANGQEENDLPPG
40 50 60 70 80 90
210 220 230 240 250 260
pF1KA0 TPDAFAQLLTCPYCDRGYKRLTSLKEHIKYRHEKNEENFSCPLCSYTFAYRTQLERHMVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPDAFAQLLTCPYCDRGYKRLTSLKEHIKYRHEKNEENFSCPLCSYTFAYRTQLERHMVT
100 110 120 130 140 150
270 280 290 300 310 320
pF1KA0 HKPGTDQHQMLTQGAGNRKFKCTECGKAFKYKHHLKEHLRIHSGEKPYECPNCKKRFSHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HKPGTDQHQMLTQGAGNRKFKCTECGKAFKYKHHLKEHLRIHSGEKPYECPNCKKRFSHS
160 170 180 190 200 210
330 340 350 360 370 380
pF1KA0 GSYSSHISSKKCIGLISVNGRMRNNIKTGSSPNSVSSSPTNSAITQLRNKLENGKPLSMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSYSSHISSKKCIGLISVNGRMRNNIKTGSSPNSVSSSPTNSAITQLRNKLENGKPLSMS
220 230 240 250 260 270
390 400 410 420 430 440
pF1KA0 EQTGLLKIKTEPLDFNDYKVLMATHGFSGTSPFMNGGLGATSPLGVHPSAQSPMQHLGVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQTGLLKIKTEPLDFNDYKVLMATHGFSGTSPFMNGGLGATSPLGVHPSAQSPMQHLGVG
280 290 300 310 320 330
450 460 470 480 490 500
pF1KA0 MEAPLLGFPTMNSNLSEVQKVLQIVDNTVSRQKMDCKAEEISKLKGYHMKDPCSQPEEQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEAPLLGFPTMNSNLSEVQKVLQIVDNTVSRQKMDCKAEEISKLKGYHMKDPCSQPEEQG
340 350 360 370 380 390
510 520 530 540 550 560
pF1KA0 VTSPNIPPVGLPVVSHNGATKSIIDYTLEKVNEAKACLQSLTTDSRRQISNIKKEKLRTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTSPNIPPVGLPVVSHNGATKSIIDYTLEKVNEAKACLQSLTTDSRRQISNIKKEKLRTL
400 410 420 430 440 450
570 580 590 600 610 620
pF1KA0 IDLVTDDKMIENHNISTPFSCQFCKESFPGPIPLHQHERYLCKMNEEIKAVLQPHENIVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDLVTDDKMIENHNISTPFSCQFCKESFPGPIPLHQHERYLCKMNEEIKAVLQPHENIVP
460 470 480 490 500 510
630 640 650 660 670 680
pF1KA0 NKAGVFVDNKALLLSSVLSEKGMTSPINPYKDHMSVLKAYYAMNMEPNSDELLKISIAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKAGVFVDNKALLLSSVLSEKGMTSPINPYKDHMSVLKAYYAMNMEPNSDELLKISIAVG
520 530 540 550 560 570
690 700 710 720 730 740
pF1KA0 LPQEFVKEWFEQRKVYQYSNSRSPSLERSSKPLAPNSNPPTKDSLLPRSPVKPMDSITSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPQEFVKEWFEQRKVYQYSNSRSPSLERSSKPLAPNSNPPTKDSLLPRSPVKPMDSITSP
580 590 600 610 620 630
750 760 770 780 790 800
pF1KA0 SIAELHNSVTNCDPPLRLTKPSHFTNIKPVEKLDHSRSNTPSPLNLSSTSSKNSHSSSYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIAELHNSVTNCDPPLRLTKPSHFTNIKPVEKLDHSRSNTPSPLNLSSTSSKNSHSSSYT
640 650 660 670 680 690
810 820 830 840 850 860
pF1KA0 PNSFSSEELQAEPLDLSLPKQMKEPKSIIATKNKTKASSISLDHNSVSSSSENSDEPLNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNSFSSEELQAEPLDLSLPKQMKEPKSIIATKNKTKASSISLDHNSVSSSSENSDEPLNL
700 710 720 730 740 750
870 880 890 900 910 920
pF1KA0 TFIKKEFSNSNNLDNKSTNPVFSMNPFSAKPLYTALPPQSAFPPATFMPPVQTSIPGLRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFIKKEFSNSNNLDNKSTNPVFSMNPFSAKPLYTALPPQSAFPPATFMPPVQTSIPGLRP
760 770 780 790 800 810
930 940 950 960 970 980
pF1KA0 YPGLDQMSFLPHMAYTYPTGAATFADMQQRRKYQRKQGFQGELLDGAQDYMSGLDDMTDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YPGLDQMSFLPHMAYTYPTGAATFADMQQRRKYQRKQGFQGELLDGAQDYMSGLDDMTDS
820 830 840 850 860 870
990 1000 1010 1020 1030 1040
pF1KA0 DSCLSRKKIKKTESGMYACDLCDKTFQKSSSLLRHKYEHTGKRPHQCQICKKAFKHKHHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSCLSRKKIKKTESGMYACDLCDKTFQKSSSLLRHKYEHTGKRPHQCQICKKAFKHKHHL
880 890 900 910 920 930
1050 1060 1070 1080 1090 1100
pF1KA0 IEHSRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSYCKREAEEREAAEREAREKGHLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEHSRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSYCKREAEEREAAEREAREKGHLE
940 950 960 970 980 990
1110 1120 1130 1140 1150 1160
pF1KA0 PTELLMNRAYLQSITPQGYSDSEERESMPRDGESEKEHEKEGEDGYGKLGRQDGDEEFEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTELLMNRAYLQSITPQGYSDSEERESMPRDGESEKEHEKEGEDGYGKLGRQDGDEEFEE
1000 1010 1020 1030 1040 1050
1170 1180 1190 1200 1210
pF1KA0 EEEESENKSMDTDPETIRDEEETGDHSMDDSSEDGKMETKSDHEEDNMEDGM
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEESENKSMDTDPETIRDEEETGDHSMDDSSEDGKMETKSDHEEDNMEDGM
1060 1070 1080 1090 1100
>>XP_016860904 (OMIM: 235730,605802) PREDICTED: zinc fin (1102 aa)
initn: 7437 init1: 7437 opt: 7437 Z-score: 3317.3 bits: 625.7 E(85289): 4.9e-178
Smith-Waterman score: 7437; 100.0% identity (100.0% similar) in 1102 aa overlap (113-1214:1-1102)
90 100 110 120 130 140
pF1KA0 EEEDEIREGGVEHPWHNNEILQASVDGPEEMKEDYDTMGPEATIQTAINNGTVKNANCTS
::::::::::::::::::::::::::::::
XP_016 MKEDYDTMGPEATIQTAINNGTVKNANCTS
10 20 30
150 160 170 180 190 200
pF1KA0 DFEEYFAKRKLEERDGHAVSIEEYLQRSDTAIIYPEAPEELSRLGTPEANGQEENDLPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFEEYFAKRKLEERDGHAVSIEEYLQRSDTAIIYPEAPEELSRLGTPEANGQEENDLPPG
40 50 60 70 80 90
210 220 230 240 250 260
pF1KA0 TPDAFAQLLTCPYCDRGYKRLTSLKEHIKYRHEKNEENFSCPLCSYTFAYRTQLERHMVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPDAFAQLLTCPYCDRGYKRLTSLKEHIKYRHEKNEENFSCPLCSYTFAYRTQLERHMVT
100 110 120 130 140 150
270 280 290 300 310 320
pF1KA0 HKPGTDQHQMLTQGAGNRKFKCTECGKAFKYKHHLKEHLRIHSGEKPYECPNCKKRFSHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HKPGTDQHQMLTQGAGNRKFKCTECGKAFKYKHHLKEHLRIHSGEKPYECPNCKKRFSHS
160 170 180 190 200 210
330 340 350 360 370 380
pF1KA0 GSYSSHISSKKCIGLISVNGRMRNNIKTGSSPNSVSSSPTNSAITQLRNKLENGKPLSMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSYSSHISSKKCIGLISVNGRMRNNIKTGSSPNSVSSSPTNSAITQLRNKLENGKPLSMS
220 230 240 250 260 270
390 400 410 420 430 440
pF1KA0 EQTGLLKIKTEPLDFNDYKVLMATHGFSGTSPFMNGGLGATSPLGVHPSAQSPMQHLGVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQTGLLKIKTEPLDFNDYKVLMATHGFSGTSPFMNGGLGATSPLGVHPSAQSPMQHLGVG
280 290 300 310 320 330
450 460 470 480 490 500
pF1KA0 MEAPLLGFPTMNSNLSEVQKVLQIVDNTVSRQKMDCKAEEISKLKGYHMKDPCSQPEEQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEAPLLGFPTMNSNLSEVQKVLQIVDNTVSRQKMDCKAEEISKLKGYHMKDPCSQPEEQG
340 350 360 370 380 390
510 520 530 540 550 560
pF1KA0 VTSPNIPPVGLPVVSHNGATKSIIDYTLEKVNEAKACLQSLTTDSRRQISNIKKEKLRTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTSPNIPPVGLPVVSHNGATKSIIDYTLEKVNEAKACLQSLTTDSRRQISNIKKEKLRTL
400 410 420 430 440 450
570 580 590 600 610 620
pF1KA0 IDLVTDDKMIENHNISTPFSCQFCKESFPGPIPLHQHERYLCKMNEEIKAVLQPHENIVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDLVTDDKMIENHNISTPFSCQFCKESFPGPIPLHQHERYLCKMNEEIKAVLQPHENIVP
460 470 480 490 500 510
630 640 650 660 670 680
pF1KA0 NKAGVFVDNKALLLSSVLSEKGMTSPINPYKDHMSVLKAYYAMNMEPNSDELLKISIAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKAGVFVDNKALLLSSVLSEKGMTSPINPYKDHMSVLKAYYAMNMEPNSDELLKISIAVG
520 530 540 550 560 570
690 700 710 720 730 740
pF1KA0 LPQEFVKEWFEQRKVYQYSNSRSPSLERSSKPLAPNSNPPTKDSLLPRSPVKPMDSITSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPQEFVKEWFEQRKVYQYSNSRSPSLERSSKPLAPNSNPPTKDSLLPRSPVKPMDSITSP
580 590 600 610 620 630
750 760 770 780 790 800
pF1KA0 SIAELHNSVTNCDPPLRLTKPSHFTNIKPVEKLDHSRSNTPSPLNLSSTSSKNSHSSSYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIAELHNSVTNCDPPLRLTKPSHFTNIKPVEKLDHSRSNTPSPLNLSSTSSKNSHSSSYT
640 650 660 670 680 690
810 820 830 840 850 860
pF1KA0 PNSFSSEELQAEPLDLSLPKQMKEPKSIIATKNKTKASSISLDHNSVSSSSENSDEPLNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNSFSSEELQAEPLDLSLPKQMKEPKSIIATKNKTKASSISLDHNSVSSSSENSDEPLNL
700 710 720 730 740 750
870 880 890 900 910 920
pF1KA0 TFIKKEFSNSNNLDNKSTNPVFSMNPFSAKPLYTALPPQSAFPPATFMPPVQTSIPGLRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFIKKEFSNSNNLDNKSTNPVFSMNPFSAKPLYTALPPQSAFPPATFMPPVQTSIPGLRP
760 770 780 790 800 810
930 940 950 960 970 980
pF1KA0 YPGLDQMSFLPHMAYTYPTGAATFADMQQRRKYQRKQGFQGELLDGAQDYMSGLDDMTDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YPGLDQMSFLPHMAYTYPTGAATFADMQQRRKYQRKQGFQGELLDGAQDYMSGLDDMTDS
820 830 840 850 860 870
990 1000 1010 1020 1030 1040
pF1KA0 DSCLSRKKIKKTESGMYACDLCDKTFQKSSSLLRHKYEHTGKRPHQCQICKKAFKHKHHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSCLSRKKIKKTESGMYACDLCDKTFQKSSSLLRHKYEHTGKRPHQCQICKKAFKHKHHL
880 890 900 910 920 930
1050 1060 1070 1080 1090 1100
pF1KA0 IEHSRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSYCKREAEEREAAEREAREKGHLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEHSRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSYCKREAEEREAAEREAREKGHLE
940 950 960 970 980 990
1110 1120 1130 1140 1150 1160
pF1KA0 PTELLMNRAYLQSITPQGYSDSEERESMPRDGESEKEHEKEGEDGYGKLGRQDGDEEFEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTELLMNRAYLQSITPQGYSDSEERESMPRDGESEKEHEKEGEDGYGKLGRQDGDEEFEE
1000 1010 1020 1030 1040 1050
1170 1180 1190 1200 1210
pF1KA0 EEEESENKSMDTDPETIRDEEETGDHSMDDSSEDGKMETKSDHEEDNMEDGM
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEESENKSMDTDPETIRDEEETGDHSMDDSSEDGKMETKSDHEEDNMEDGM
1060 1070 1080 1090 1100
>>NP_001165124 (OMIM: 235730,605802) zinc finger E-box-b (1190 aa)
initn: 7303 init1: 7303 opt: 7315 Z-score: 3262.9 bits: 615.8 E(85289): 5.3e-175
Smith-Waterman score: 7993; 98.0% identity (98.0% similar) in 1214 aa overlap (1-1214:1-1190)
10 20 30 40 50 60
pF1KA0 MKQPIMADGPRCKRRKQANPRRKNVVNYDNVVDTGSETDEEDKLHIAEDDGIANPLDQET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKQPIMADGPRCKRRKQANPRRKNVVNYDNVVDTGSETDEEDKLHIAEDDGIANPLDQET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 SPASVPNHESSPHVSQALLPREEEEDEIREGGVEHPWHNNEILQASVDGPEEMKEDYDTM
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPASVPNHESSPHVSQALLPREEEEDEIREGGVEHPWHNNEILQASVDGP----------
70 80 90 100 110
130 140 150 160 170 180
pF1KA0 GPEATIQTAINNGTVKNANCTSDFEEYFAKRKLEERDGHAVSIEEYLQRSDTAIIYPEAP
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --------------VKNANCTSDFEEYFAKRKLEERDGHAVSIEEYLQRSDTAIIYPEAP
120 130 140 150
190 200 210 220 230 240
pF1KA0 EELSRLGTPEANGQEENDLPPGTPDAFAQLLTCPYCDRGYKRLTSLKEHIKYRHEKNEEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EELSRLGTPEANGQEENDLPPGTPDAFAQLLTCPYCDRGYKRLTSLKEHIKYRHEKNEEN
160 170 180 190 200 210
250 260 270 280 290 300
pF1KA0 FSCPLCSYTFAYRTQLERHMVTHKPGTDQHQMLTQGAGNRKFKCTECGKAFKYKHHLKEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSCPLCSYTFAYRTQLERHMVTHKPGTDQHQMLTQGAGNRKFKCTECGKAFKYKHHLKEH
220 230 240 250 260 270
310 320 330 340 350 360
pF1KA0 LRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCIGLISVNGRMRNNIKTGSSPNSVSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCIGLISVNGRMRNNIKTGSSPNSVSSS
280 290 300 310 320 330
370 380 390 400 410 420
pF1KA0 PTNSAITQLRNKLENGKPLSMSEQTGLLKIKTEPLDFNDYKVLMATHGFSGTSPFMNGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTNSAITQLRNKLENGKPLSMSEQTGLLKIKTEPLDFNDYKVLMATHGFSGTSPFMNGGL
340 350 360 370 380 390
430 440 450 460 470 480
pF1KA0 GATSPLGVHPSAQSPMQHLGVGMEAPLLGFPTMNSNLSEVQKVLQIVDNTVSRQKMDCKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GATSPLGVHPSAQSPMQHLGVGMEAPLLGFPTMNSNLSEVQKVLQIVDNTVSRQKMDCKA
400 410 420 430 440 450
490 500 510 520 530 540
pF1KA0 EEISKLKGYHMKDPCSQPEEQGVTSPNIPPVGLPVVSHNGATKSIIDYTLEKVNEAKACL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEISKLKGYHMKDPCSQPEEQGVTSPNIPPVGLPVVSHNGATKSIIDYTLEKVNEAKACL
460 470 480 490 500 510
550 560 570 580 590 600
pF1KA0 QSLTTDSRRQISNIKKEKLRTLIDLVTDDKMIENHNISTPFSCQFCKESFPGPIPLHQHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSLTTDSRRQISNIKKEKLRTLIDLVTDDKMIENHNISTPFSCQFCKESFPGPIPLHQHE
520 530 540 550 560 570
610 620 630 640 650 660
pF1KA0 RYLCKMNEEIKAVLQPHENIVPNKAGVFVDNKALLLSSVLSEKGMTSPINPYKDHMSVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYLCKMNEEIKAVLQPHENIVPNKAGVFVDNKALLLSSVLSEKGMTSPINPYKDHMSVLK
580 590 600 610 620 630
670 680 690 700 710 720
pF1KA0 AYYAMNMEPNSDELLKISIAVGLPQEFVKEWFEQRKVYQYSNSRSPSLERSSKPLAPNSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYYAMNMEPNSDELLKISIAVGLPQEFVKEWFEQRKVYQYSNSRSPSLERSSKPLAPNSN
640 650 660 670 680 690
730 740 750 760 770 780
pF1KA0 PPTKDSLLPRSPVKPMDSITSPSIAELHNSVTNCDPPLRLTKPSHFTNIKPVEKLDHSRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPTKDSLLPRSPVKPMDSITSPSIAELHNSVTNCDPPLRLTKPSHFTNIKPVEKLDHSRS
700 710 720 730 740 750
790 800 810 820 830 840
pF1KA0 NTPSPLNLSSTSSKNSHSSSYTPNSFSSEELQAEPLDLSLPKQMKEPKSIIATKNKTKAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTPSPLNLSSTSSKNSHSSSYTPNSFSSEELQAEPLDLSLPKQMKEPKSIIATKNKTKAS
760 770 780 790 800 810
850 860 870 880 890 900
pF1KA0 SISLDHNSVSSSSENSDEPLNLTFIKKEFSNSNNLDNKSTNPVFSMNPFSAKPLYTALPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SISLDHNSVSSSSENSDEPLNLTFIKKEFSNSNNLDNKSTNPVFSMNPFSAKPLYTALPP
820 830 840 850 860 870
910 920 930 940 950 960
pF1KA0 QSAFPPATFMPPVQTSIPGLRPYPGLDQMSFLPHMAYTYPTGAATFADMQQRRKYQRKQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSAFPPATFMPPVQTSIPGLRPYPGLDQMSFLPHMAYTYPTGAATFADMQQRRKYQRKQG
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KA0 FQGELLDGAQDYMSGLDDMTDSDSCLSRKKIKKTESGMYACDLCDKTFQKSSSLLRHKYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQGELLDGAQDYMSGLDDMTDSDSCLSRKKIKKTESGMYACDLCDKTFQKSSSLLRHKYE
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KA0 HTGKRPHQCQICKKAFKHKHHLIEHSRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HTGKRPHQCQICKKAFKHKHHLIEHSRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSY
1000 1010 1020 1030 1040 1050
1090 1100 1110 1120 1130 1140
pF1KA0 CKREAEEREAAEREAREKGHLEPTELLMNRAYLQSITPQGYSDSEERESMPRDGESEKEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CKREAEEREAAEREAREKGHLEPTELLMNRAYLQSITPQGYSDSEERESMPRDGESEKEH
1060 1070 1080 1090 1100 1110
1150 1160 1170 1180 1190 1200
pF1KA0 EKEGEDGYGKLGRQDGDEEFEEEEEESENKSMDTDPETIRDEEETGDHSMDDSSEDGKME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKEGEDGYGKLGRQDGDEEFEEEEEESENKSMDTDPETIRDEEETGDHSMDDSSEDGKME
1120 1130 1140 1150 1160 1170
1210
pF1KA0 TKSDHEEDNMEDGM
::::::::::::::
NP_001 TKSDHEEDNMEDGM
1180 1190
>>NP_001310580 (OMIM: 189909,609141,613270) zinc finger (906 aa)
initn: 1664 init1: 781 opt: 1071 Z-score: 499.1 bits: 104.0 E(85289): 4.6e-21
Smith-Waterman score: 2167; 43.6% identity (68.9% similar) in 952 aa overlap (260-1195:1-881)
230 240 250 260 270 280
pF1KA0 IKYRHEKNEENFSCPLCSYTFAYRTQLERHMVTHKPGTDQHQMLTQGAGNRKFKCTECGK
:..:: : ::... ::.. :::::::::::
NP_001 MTSHKSGRDQRHV-TQSGCNRKFKCTECGK
10 20
290 300 310 320 330 340
pF1KA0 AFKYKHHLKEHLRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCIGLISVNGRMRNNIK
::::::::::::::::::::::::::::::::::::::::::::::.:: :::: :...:
NP_001 AFKYKHHLKEHLRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCISLIPVNGRPRTGLK
30 40 50 60 70 80
350 360 370 380 390 400
pF1KA0 TG--SSPNSVSSSPTNSAITQLRNKLENGKPLSMSEQTGLLKIKTEPLDFNDYKVLMATH
:. ::: :.:.:: . . :.:.:.:: ::: .:: .. .:::::.:. ..: ....
NP_001 TSQCSSP-SLSASPGSPTRPQIRQKIEN-KPL--QEQLSVNQIKTEPVDY-EFKPIVVAS
90 100 110 120 130 140
410 420 430 440 450 460
pF1KA0 GFSGTSPFMNGGLGATSPLGVHPSAQSPMQHLGVGMEAPLLGFPT-MNSNLSEVQKVLQI
:.. ..:..:: . . .:: . : :. .: . . : .:. . .. :::..:.::..
NP_001 GINCSTPLQNGVFTGGGPLQATSSPQGMVQAVVL----PTVGLVSPISINLSDIQNVLKV
150 160 170 180 190 200
470 480 490 500 510 520
pF1KA0 -VDNTVSRQKMDCKAEEISKLKGYHMKDPCSQPEEQGVTSPNIPPVGLPVVSHNGATKSI
::..: :: .. . ..: . ... ..: .:: : : ..::.:...:.:: :
NP_001 AVDGNVIRQVLENNQ---ANLASKEQETINASPIQQGGHSV-ISAISLPLVDQDGTTKII
210 220 230 240 250
530 540 550 560 570 580
pF1KA0 IDYTLEKVNEAKACLQSLTTDSRRQISNIKKEKLRTLIDLVTD-DKMIENH-NISTPFSC
:.:.::. .. .. :.: .. .. :.::: . . .. :: .:. : :: . :
NP_001 INYSLEQPSQLQVVPQNLKKENPVATNSCKSEKLPEDLTVKSEKDKSFEGGVNDSTCLLC
260 270 280 290 300 310
590 600 610 620 630 640
pF1KA0 QFCKESFPGPI-PLHQHERYLCKMNEEIKAVLQPHENIVPNKAGVFVDNKALLLSSVLSE
. : :: : : . ..: ..: :: : .. ... .::. ..
NP_001 DDC----PGDINALPELKHY------DLKQPTQP-----PPLPAAEAEKPESSVSSATGD
320 330 340 350 360
650 660 670 680 690 700
pF1KA0 KGMTSPINPYKDHMSVLKAYYAMNMEPNSDELLKISIAVGLPQEFVKEWFEQRKVYQYSN
... : :. .:.::::::.: .:...:: ::. .:.:: . ::.:::. .. : :
NP_001 GNLSPSQPPLKNLLSLLKAYYALNAQPSAEELSKIADSVNLPLDVVKKWFEKMQAGQISV
370 380 390 400 410 420
710 720 730 740 750 760
pF1KA0 SRSPSLERSSKPLAPNSNPPTKDSLLPRSPVKPMDSITSPSIAELHNSVTNCDPPLRLTK
.::.: .:. : : .. :.: :. : . : ..:..: . ::..:.
NP_001 -------QSSEPSSPE---PGKVNI----PAKNNDQPQSANANEPQDSTVNLQSPLKMTN
430 440 450 460
770 780 790 800 810 820
pF1KA0 PSHFTNIKPV-EKLDHSRSNTPSPLNLSSTSSKNSHSSSYTPNSFSSEELQAEPLDLSLP
. . :: . :::.:::: :. .::.:... :: .. ..:: :.::::::::
NP_001 ----SPVLPVGSTTNGSRSSTPSPSPLNLSSSRNTQGYLYTAEG-AQEEPQVEPLDLSLP
470 480 490 500 510 520
830 840 850 860 870 880
pF1KA0 KQMKEPKSIIATKNKTKASSISLDHNSVSSSSENSDEPLNLTFIKKEFSNSNNLDNKSTN
::. : .. ... :. .::: : .: :::::. ::: .... . . ..
NP_001 KQQGE---LL-----ERSTITSVYQNSVYSVQE---EPLNLSCAKKEPQKDSCVTD--SE
530 540 550 560
890 900 910 920 930 940
pF1KA0 PVFSMNPFSAKPLYTALPPQSAFPPATFMPPVQTSIPGLRPYPGLDQMSFLPHMAYTYPT
:: .. : ::.:. :.: .: :. :.:.: :: . : ..:..:::: :
NP_001 PVVNVIPPSANPINIAIPTVTAQLPTIVAIADQNSVPCLRALAANKQTILIPQVAYTYST
570 580 590 600 610 620
950 960 970 980 990 1000
pF1KA0 GAATFADMQQRRKYQRKQGFQGELLDGAQDYMSGLDDMTDSDSCLSRKKIKKTESGMYAC
... : .. : . .: : : : ... .:...:..:::: .::..:::.:::::
NP_001 -TVSPAVQEPPLKVIQPNGNQDERQDTSSEGVSNVEDQNDSDSTPPKKKMRKTENGMYAC
630 640 650 660 670 680
1010 1020 1030 1040 1050 1060
pF1KA0 DLCDKTFQKSSSLLRHKYEHTGKRPHQCQICKKAFKHKHHLIEHSRLHSGEKPYQCDKCG
::::: ::::::::::::::::::::.: ::::::::::::::: :::::::::::::::
NP_001 DLCDKIFQKSSSLLRHKYEHTGKRPHECGICKKAFKHKHHLIEHMRLHSGEKPYQCDKCG
690 700 710 720 730 740
1070 1080 1090 1100 1110 1120
pF1KA0 KRFSHSGSYSQHMNHRYSYCKREAEEREAAEREAREKGHLEPTELLMNRAYLQSITP-QG
:::::::::::::::::::::::::::...:.: : : : :.: :. .: ::
NP_001 KRFSHSGSYSQHMNHRYSYCKREAEERDSTEQE--EAG---P-EILSNEHVGARASPSQG
750 760 770 780 790 800
1130 1140 1150 1160 1170
pF1KA0 YSDSEERESMPR--DGESEKEHEKEGEDGY-----GKLGRQDGDEEFEEEEEESENKSMD
::.::::. : : .::::.:.: .. . . .:::: :::::: :.. ..
NP_001 --DSDERESLTREEDEDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEVE
810 820 830 840 850 860
1180 1190 1200 1210
pF1KA0 TDPETIRDEEETGDHSMDDSSEDGKMETKSDHEEDNMEDGM
. :. .: .: :: .:
NP_001 -EAENEGEEAKTEGLMKDDRAESQASSLGQKVGESSEQVSEEKTNEA
870 880 890 900
>>NP_001310591 (OMIM: 189909,609141,613270) zinc finger (906 aa)
initn: 1664 init1: 781 opt: 1071 Z-score: 499.1 bits: 104.0 E(85289): 4.6e-21
Smith-Waterman score: 2167; 43.6% identity (68.9% similar) in 952 aa overlap (260-1195:1-881)
230 240 250 260 270 280
pF1KA0 IKYRHEKNEENFSCPLCSYTFAYRTQLERHMVTHKPGTDQHQMLTQGAGNRKFKCTECGK
:..:: : ::... ::.. :::::::::::
NP_001 MTSHKSGRDQRHV-TQSGCNRKFKCTECGK
10 20
290 300 310 320 330 340
pF1KA0 AFKYKHHLKEHLRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCIGLISVNGRMRNNIK
::::::::::::::::::::::::::::::::::::::::::::::.:: :::: :...:
NP_001 AFKYKHHLKEHLRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCISLIPVNGRPRTGLK
30 40 50 60 70 80
350 360 370 380 390 400
pF1KA0 TG--SSPNSVSSSPTNSAITQLRNKLENGKPLSMSEQTGLLKIKTEPLDFNDYKVLMATH
:. ::: :.:.:: . . :.:.:.:: ::: .:: .. .:::::.:. ..: ....
NP_001 TSQCSSP-SLSASPGSPTRPQIRQKIEN-KPL--QEQLSVNQIKTEPVDY-EFKPIVVAS
90 100 110 120 130 140
410 420 430 440 450 460
pF1KA0 GFSGTSPFMNGGLGATSPLGVHPSAQSPMQHLGVGMEAPLLGFPT-MNSNLSEVQKVLQI
:.. ..:..:: . . .:: . : :. .: . . : .:. . .. :::..:.::..
NP_001 GINCSTPLQNGVFTGGGPLQATSSPQGMVQAVVL----PTVGLVSPISINLSDIQNVLKV
150 160 170 180 190 200
470 480 490 500 510 520
pF1KA0 -VDNTVSRQKMDCKAEEISKLKGYHMKDPCSQPEEQGVTSPNIPPVGLPVVSHNGATKSI
::..: :: .. . ..: . ... ..: .:: : : ..::.:...:.:: :
NP_001 AVDGNVIRQVLENNQ---ANLASKEQETINASPIQQGGHSV-ISAISLPLVDQDGTTKII
210 220 230 240 250
530 540 550 560 570 580
pF1KA0 IDYTLEKVNEAKACLQSLTTDSRRQISNIKKEKLRTLIDLVTD-DKMIENH-NISTPFSC
:.:.::. .. .. :.: .. .. :.::: . . .. :: .:. : :: . :
NP_001 INYSLEQPSQLQVVPQNLKKENPVATNSCKSEKLPEDLTVKSEKDKSFEGGVNDSTCLLC
260 270 280 290 300 310
590 600 610 620 630 640
pF1KA0 QFCKESFPGPI-PLHQHERYLCKMNEEIKAVLQPHENIVPNKAGVFVDNKALLLSSVLSE
. : :: : : . ..: ..: :: : .. ... .::. ..
NP_001 DDC----PGDINALPELKHY------DLKQPTQP-----PPLPAAEAEKPESSVSSATGD
320 330 340 350 360
650 660 670 680 690 700
pF1KA0 KGMTSPINPYKDHMSVLKAYYAMNMEPNSDELLKISIAVGLPQEFVKEWFEQRKVYQYSN
... : :. .:.::::::.: .:...:: ::. .:.:: . ::.:::. .. : :
NP_001 GNLSPSQPPLKNLLSLLKAYYALNAQPSAEELSKIADSVNLPLDVVKKWFEKMQAGQISV
370 380 390 400 410 420
710 720 730 740 750 760
pF1KA0 SRSPSLERSSKPLAPNSNPPTKDSLLPRSPVKPMDSITSPSIAELHNSVTNCDPPLRLTK
.::.: .:. : : .. :.: :. : . : ..:..: . ::..:.
NP_001 -------QSSEPSSPE---PGKVNI----PAKNNDQPQSANANEPQDSTVNLQSPLKMTN
430 440 450 460
770 780 790 800 810 820
pF1KA0 PSHFTNIKPV-EKLDHSRSNTPSPLNLSSTSSKNSHSSSYTPNSFSSEELQAEPLDLSLP
. . :: . :::.:::: :. .::.:... :: .. ..:: :.::::::::
NP_001 ----SPVLPVGSTTNGSRSSTPSPSPLNLSSSRNTQGYLYTAEG-AQEEPQVEPLDLSLP
470 480 490 500 510 520
830 840 850 860 870 880
pF1KA0 KQMKEPKSIIATKNKTKASSISLDHNSVSSSSENSDEPLNLTFIKKEFSNSNNLDNKSTN
::. : .. ... :. .::: : .: :::::. ::: .... . . ..
NP_001 KQQGE---LL-----ERSTITSVYQNSVYSVQE---EPLNLSCAKKEPQKDSCVTD--SE
530 540 550 560
890 900 910 920 930 940
pF1KA0 PVFSMNPFSAKPLYTALPPQSAFPPATFMPPVQTSIPGLRPYPGLDQMSFLPHMAYTYPT
:: .. : ::.:. :.: .: :. :.:.: :: . : ..:..:::: :
NP_001 PVVNVIPPSANPINIAIPTVTAQLPTIVAIADQNSVPCLRALAANKQTILIPQVAYTYST
570 580 590 600 610 620
950 960 970 980 990 1000
pF1KA0 GAATFADMQQRRKYQRKQGFQGELLDGAQDYMSGLDDMTDSDSCLSRKKIKKTESGMYAC
... : .. : . .: : : : ... .:...:..:::: .::..:::.:::::
NP_001 -TVSPAVQEPPLKVIQPNGNQDERQDTSSEGVSNVEDQNDSDSTPPKKKMRKTENGMYAC
630 640 650 660 670 680
1010 1020 1030 1040 1050 1060
pF1KA0 DLCDKTFQKSSSLLRHKYEHTGKRPHQCQICKKAFKHKHHLIEHSRLHSGEKPYQCDKCG
::::: ::::::::::::::::::::.: ::::::::::::::: :::::::::::::::
NP_001 DLCDKIFQKSSSLLRHKYEHTGKRPHECGICKKAFKHKHHLIEHMRLHSGEKPYQCDKCG
690 700 710 720 730 740
1070 1080 1090 1100 1110 1120
pF1KA0 KRFSHSGSYSQHMNHRYSYCKREAEEREAAEREAREKGHLEPTELLMNRAYLQSITP-QG
:::::::::::::::::::::::::::...:.: : : : :.: :. .: ::
NP_001 KRFSHSGSYSQHMNHRYSYCKREAEERDSTEQE--EAG---P-EILSNEHVGARASPSQG
750 760 770 780 790 800
1130 1140 1150 1160 1170
pF1KA0 YSDSEERESMPR--DGESEKEHEKEGEDGY-----GKLGRQDGDEEFEEEEEESENKSMD
::.::::. : : .::::.:.: .. . . .:::: :::::: :.. ..
NP_001 --DSDERESLTREEDEDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEVE
810 820 830 840 850 860
1180 1190 1200 1210
pF1KA0 TDPETIRDEEETGDHSMDDSSEDGKMETKSDHEEDNMEDGM
. :. .: .: :: .:
NP_001 -EAENEGEEAKTEGLMKDDRAESQASSLGQKVGESSEQVSEEKTNEA
870 880 890 900
>>XP_016872092 (OMIM: 189909,609141,613270) PREDICTED: z (906 aa)
initn: 1664 init1: 781 opt: 1071 Z-score: 499.1 bits: 104.0 E(85289): 4.6e-21
Smith-Waterman score: 2167; 43.6% identity (68.9% similar) in 952 aa overlap (260-1195:1-881)
230 240 250 260 270 280
pF1KA0 IKYRHEKNEENFSCPLCSYTFAYRTQLERHMVTHKPGTDQHQMLTQGAGNRKFKCTECGK
:..:: : ::... ::.. :::::::::::
XP_016 MTSHKSGRDQRHV-TQSGCNRKFKCTECGK
10 20
290 300 310 320 330 340
pF1KA0 AFKYKHHLKEHLRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCIGLISVNGRMRNNIK
::::::::::::::::::::::::::::::::::::::::::::::.:: :::: :...:
XP_016 AFKYKHHLKEHLRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCISLIPVNGRPRTGLK
30 40 50 60 70 80
350 360 370 380 390 400
pF1KA0 TG--SSPNSVSSSPTNSAITQLRNKLENGKPLSMSEQTGLLKIKTEPLDFNDYKVLMATH
:. ::: :.:.:: . . :.:.:.:: ::: .:: .. .:::::.:. ..: ....
XP_016 TSQCSSP-SLSASPGSPTRPQIRQKIEN-KPL--QEQLSVNQIKTEPVDY-EFKPIVVAS
90 100 110 120 130 140
410 420 430 440 450 460
pF1KA0 GFSGTSPFMNGGLGATSPLGVHPSAQSPMQHLGVGMEAPLLGFPT-MNSNLSEVQKVLQI
:.. ..:..:: . . .:: . : :. .: . . : .:. . .. :::..:.::..
XP_016 GINCSTPLQNGVFTGGGPLQATSSPQGMVQAVVL----PTVGLVSPISINLSDIQNVLKV
150 160 170 180 190 200
470 480 490 500 510 520
pF1KA0 -VDNTVSRQKMDCKAEEISKLKGYHMKDPCSQPEEQGVTSPNIPPVGLPVVSHNGATKSI
::..: :: .. . ..: . ... ..: .:: : : ..::.:...:.:: :
XP_016 AVDGNVIRQVLENNQ---ANLASKEQETINASPIQQGGHSV-ISAISLPLVDQDGTTKII
210 220 230 240 250
530 540 550 560 570 580
pF1KA0 IDYTLEKVNEAKACLQSLTTDSRRQISNIKKEKLRTLIDLVTD-DKMIENH-NISTPFSC
:.:.::. .. .. :.: .. .. :.::: . . .. :: .:. : :: . :
XP_016 INYSLEQPSQLQVVPQNLKKENPVATNSCKSEKLPEDLTVKSEKDKSFEGGVNDSTCLLC
260 270 280 290 300 310
590 600 610 620 630 640
pF1KA0 QFCKESFPGPI-PLHQHERYLCKMNEEIKAVLQPHENIVPNKAGVFVDNKALLLSSVLSE
. : :: : : . ..: ..: :: : .. ... .::. ..
XP_016 DDC----PGDINALPELKHY------DLKQPTQP-----PPLPAAEAEKPESSVSSATGD
320 330 340 350 360
650 660 670 680 690 700
pF1KA0 KGMTSPINPYKDHMSVLKAYYAMNMEPNSDELLKISIAVGLPQEFVKEWFEQRKVYQYSN
... : :. .:.::::::.: .:...:: ::. .:.:: . ::.:::. .. : :
XP_016 GNLSPSQPPLKNLLSLLKAYYALNAQPSAEELSKIADSVNLPLDVVKKWFEKMQAGQISV
370 380 390 400 410 420
710 720 730 740 750 760
pF1KA0 SRSPSLERSSKPLAPNSNPPTKDSLLPRSPVKPMDSITSPSIAELHNSVTNCDPPLRLTK
.::.: .:. : : .. :.: :. : . : ..:..: . ::..:.
XP_016 -------QSSEPSSPE---PGKVNI----PAKNNDQPQSANANEPQDSTVNLQSPLKMTN
430 440 450 460
770 780 790 800 810 820
pF1KA0 PSHFTNIKPV-EKLDHSRSNTPSPLNLSSTSSKNSHSSSYTPNSFSSEELQAEPLDLSLP
. . :: . :::.:::: :. .::.:... :: .. ..:: :.::::::::
XP_016 ----SPVLPVGSTTNGSRSSTPSPSPLNLSSSRNTQGYLYTAEG-AQEEPQVEPLDLSLP
470 480 490 500 510 520
830 840 850 860 870 880
pF1KA0 KQMKEPKSIIATKNKTKASSISLDHNSVSSSSENSDEPLNLTFIKKEFSNSNNLDNKSTN
::. : .. ... :. .::: : .: :::::. ::: .... . . ..
XP_016 KQQGE---LL-----ERSTITSVYQNSVYSVQE---EPLNLSCAKKEPQKDSCVTD--SE
530 540 550 560
890 900 910 920 930 940
pF1KA0 PVFSMNPFSAKPLYTALPPQSAFPPATFMPPVQTSIPGLRPYPGLDQMSFLPHMAYTYPT
:: .. : ::.:. :.: .: :. :.:.: :: . : ..:..:::: :
XP_016 PVVNVIPPSANPINIAIPTVTAQLPTIVAIADQNSVPCLRALAANKQTILIPQVAYTYST
570 580 590 600 610 620
950 960 970 980 990 1000
pF1KA0 GAATFADMQQRRKYQRKQGFQGELLDGAQDYMSGLDDMTDSDSCLSRKKIKKTESGMYAC
... : .. : . .: : : : ... .:...:..:::: .::..:::.:::::
XP_016 -TVSPAVQEPPLKVIQPNGNQDERQDTSSEGVSNVEDQNDSDSTPPKKKMRKTENGMYAC
630 640 650 660 670 680
1010 1020 1030 1040 1050 1060
pF1KA0 DLCDKTFQKSSSLLRHKYEHTGKRPHQCQICKKAFKHKHHLIEHSRLHSGEKPYQCDKCG
::::: ::::::::::::::::::::.: ::::::::::::::: :::::::::::::::
XP_016 DLCDKIFQKSSSLLRHKYEHTGKRPHECGICKKAFKHKHHLIEHMRLHSGEKPYQCDKCG
690 700 710 720 730 740
1070 1080 1090 1100 1110 1120
pF1KA0 KRFSHSGSYSQHMNHRYSYCKREAEEREAAEREAREKGHLEPTELLMNRAYLQSITP-QG
:::::::::::::::::::::::::::...:.: : : : :.: :. .: ::
XP_016 KRFSHSGSYSQHMNHRYSYCKREAEERDSTEQE--EAG---P-EILSNEHVGARASPSQG
750 760 770 780 790 800
1130 1140 1150 1160 1170
pF1KA0 YSDSEERESMPR--DGESEKEHEKEGEDGY-----GKLGRQDGDEEFEEEEEESENKSMD
::.::::. : : .::::.:.: .. . . .:::: :::::: :.. ..
XP_016 --DSDERESLTREEDEDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEVE
810 820 830 840 850 860
1180 1190 1200 1210
pF1KA0 TDPETIRDEEETGDHSMDDSSEDGKMETKSDHEEDNMEDGM
. :. .: .: :: .:
XP_016 -EAENEGEEAKTEGLMKDDRAESQASSLGQKVGESSEQVSEEKTNEA
870 880 890 900
1214 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 00:45:19 2016 done: Fri Nov 4 00:45:21 2016
Total Scan time: 14.360 Total Display time: 0.500
Function used was FASTA [36.3.4 Apr, 2011]