Result of FASTA (ccds) for
pF1KA0551
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0551, 1360 aa
1>>>pF1KA0551 1360 - 1360 aa - 1360 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 16.9744+/-0.00146; mu= -30.5451+/- 0.088
mean_var=704.0381+/-149.489, 0's: 0 Z-trim(113.5): 527 B-trim: 103 in 1/53
Lambda= 0.048337
statistics sampled from 13579 (14138) to 13579 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.728), E-opt: 0.2 (0.434), width: 16
Scan time: 6.530
The best scores are: opt bits E(32554)
CCDS46956.1 TNIK gene_id:23043|Hs108|chr3 (1360) 9018 645.3 3.3e-184
CCDS54679.1 TNIK gene_id:23043|Hs108|chr3 (1352) 8943 640.1 1.2e-182
CCDS54676.1 TNIK gene_id:23043|Hs108|chr3 (1331) 6028 436.8 1.9e-121
CCDS54675.1 TNIK gene_id:23043|Hs108|chr3 (1323) 5919 429.2 3.7e-119
CCDS54678.1 TNIK gene_id:23043|Hs108|chr3 (1305) 5232 381.3 9.6e-105
CCDS54674.1 TNIK gene_id:23043|Hs108|chr3 (1276) 5217 380.2 1.9e-104
CCDS54673.1 TNIK gene_id:23043|Hs108|chr3 (1268) 5122 373.6 1.9e-102
CCDS54677.1 TNIK gene_id:23043|Hs108|chr3 (1297) 5092 371.5 8.3e-102
CCDS74546.1 MAP4K4 gene_id:9448|Hs108|chr2 (1273) 2908 219.2 5.8e-56
CCDS82487.1 MAP4K4 gene_id:9448|Hs108|chr2 (1165) 2791 211.0 1.5e-53
CCDS56130.1 MAP4K4 gene_id:9448|Hs108|chr2 (1239) 2758 208.7 7.9e-53
CCDS45588.1 MINK1 gene_id:50488|Hs108|chr17 (1332) 2529 192.8 5.4e-48
CCDS45590.1 MINK1 gene_id:50488|Hs108|chr17 (1312) 2395 183.5 3.5e-45
CCDS45589.1 MINK1 gene_id:50488|Hs108|chr17 (1303) 2344 179.9 4.1e-44
CCDS65305.1 NRK gene_id:203447|Hs108|chrX (1582) 1239 102.9 7.5e-21
CCDS7148.1 MYO3A gene_id:53904|Hs108|chr10 (1616) 1023 87.8 2.6e-16
CCDS46446.1 MYO3B gene_id:140469|Hs108|chr2 (1314) 999 86.1 7e-16
CCDS42773.1 MYO3B gene_id:140469|Hs108|chr2 (1341) 999 86.1 7.1e-16
CCDS58707.1 MAP4K3 gene_id:8491|Hs108|chr2 ( 873) 905 79.4 4.7e-14
CCDS1803.1 MAP4K3 gene_id:8491|Hs108|chr2 ( 894) 903 79.3 5.3e-14
CCDS42564.1 MAP4K1 gene_id:11184|Hs108|chr19 ( 821) 838 74.8 1.1e-12
CCDS59385.1 MAP4K1 gene_id:11184|Hs108|chr19 ( 833) 838 74.8 1.2e-12
CCDS2549.1 STK25 gene_id:10494|Hs108|chr2 ( 426) 823 73.5 1.4e-12
CCDS81582.1 MAP4K2 gene_id:5871|Hs108|chr11 ( 812) 832 74.3 1.5e-12
CCDS8082.1 MAP4K2 gene_id:5871|Hs108|chr11 ( 820) 832 74.3 1.5e-12
CCDS14631.1 STK26 gene_id:51765|Hs108|chrX ( 416) 818 73.2 1.7e-12
CCDS76334.1 SLK gene_id:9748|Hs108|chr10 (1204) 823 73.8 3.2e-12
CCDS7553.1 SLK gene_id:9748|Hs108|chr10 (1235) 823 73.8 3.3e-12
CCDS13341.1 STK4 gene_id:6789|Hs108|chr20 ( 487) 799 71.9 4.9e-12
CCDS32001.1 STK24 gene_id:8428|Hs108|chr13 ( 431) 791 71.3 6.5e-12
CCDS9488.1 STK24 gene_id:8428|Hs108|chr13 ( 443) 791 71.3 6.7e-12
CCDS47900.1 STK3 gene_id:6788|Hs108|chr8 ( 491) 779 70.5 1.3e-11
CCDS59108.1 STK3 gene_id:6788|Hs108|chr8 ( 519) 779 70.5 1.4e-11
CCDS34290.1 STK10 gene_id:6793|Hs108|chr5 ( 968) 780 70.7 2.2e-11
CCDS63200.1 STK25 gene_id:10494|Hs108|chr2 ( 349) 740 67.7 6.5e-11
CCDS48168.1 STK26 gene_id:51765|Hs108|chrX ( 339) 733 67.2 8.9e-11
>>CCDS46956.1 TNIK gene_id:23043|Hs108|chr3 (1360 aa)
initn: 9018 init1: 9018 opt: 9018 Z-score: 3420.6 bits: 645.3 E(32554): 3.3e-184
Smith-Waterman score: 9018; 100.0% identity (100.0% similar) in 1360 aa overlap (1-1360:1-1360)
10 20 30 40 50 60
pF1KA0 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360
pF1KA0 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
::::::::::::::::::::::::::::::::::::::::
CCDS46 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
1330 1340 1350 1360
>>CCDS54679.1 TNIK gene_id:23043|Hs108|chr3 (1352 aa)
initn: 5289 init1: 5289 opt: 8943 Z-score: 3392.3 bits: 640.1 E(32554): 1.2e-182
Smith-Waterman score: 8943; 99.4% identity (99.4% similar) in 1360 aa overlap (1-1360:1-1352)
10 20 30 40 50 60
pF1KA0 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
:::::::::::::: ::::::::::::::::::::::::::::::::::::::
CCDS54 PEESRDITRPSRPA--------DLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
790 800 810 820 830
850 860 870 880 890 900
pF1KA0 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
840 850 860 870 880 890
910 920 930 940 950 960
pF1KA0 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KA0 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KA0 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KA0 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KA0 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KA0 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KA0 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360
pF1KA0 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
::::::::::::::::::::::::::::::::::::::::
CCDS54 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
1320 1330 1340 1350
>>CCDS54676.1 TNIK gene_id:23043|Hs108|chr3 (1331 aa)
initn: 5911 init1: 5911 opt: 6028 Z-score: 2293.8 bits: 436.8 E(32554): 1.9e-121
Smith-Waterman score: 8771; 97.9% identity (97.9% similar) in 1360 aa overlap (1-1360:1-1331)
10 20 30 40 50 60
pF1KA0 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
:::::::::::::::::::::::::: :::::
CCDS54 REQRRHYEEQMRREEERRRAEHEQEY-----------------------------KRKQL
430 440 450
490 500 510 520 530 540
pF1KA0 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
460 470 480 490 500 510
550 560 570 580 590 600
pF1KA0 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
520 530 540 550 560 570
610 620 630 640 650 660
pF1KA0 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
580 590 600 610 620 630
670 680 690 700 710 720
pF1KA0 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
640 650 660 670 680 690
730 740 750 760 770 780
pF1KA0 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
700 710 720 730 740 750
790 800 810 820 830 840
pF1KA0 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
760 770 780 790 800 810
850 860 870 880 890 900
pF1KA0 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
820 830 840 850 860 870
910 920 930 940 950 960
pF1KA0 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KA0 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KA0 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
1000 1010 1020 1030 1040 1050
1090 1100 1110 1120 1130 1140
pF1KA0 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
1060 1070 1080 1090 1100 1110
1150 1160 1170 1180 1190 1200
pF1KA0 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
1120 1130 1140 1150 1160 1170
1210 1220 1230 1240 1250 1260
pF1KA0 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
1180 1190 1200 1210 1220 1230
1270 1280 1290 1300 1310 1320
pF1KA0 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
1240 1250 1260 1270 1280 1290
1330 1340 1350 1360
pF1KA0 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
::::::::::::::::::::::::::::::::::::::::
CCDS54 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
1300 1310 1320 1330
>>CCDS54675.1 TNIK gene_id:23043|Hs108|chr3 (1323 aa)
initn: 6747 init1: 3742 opt: 5919 Z-score: 2252.8 bits: 429.2 E(32554): 3.7e-119
Smith-Waterman score: 8696; 97.3% identity (97.3% similar) in 1360 aa overlap (1-1360:1-1323)
10 20 30 40 50 60
pF1KA0 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
:::::::::::::::::::::::::: :::::
CCDS54 REQRRHYEEQMRREEERRRAEHEQEY-----------------------------KRKQL
430 440 450
490 500 510 520 530 540
pF1KA0 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
460 470 480 490 500 510
550 560 570 580 590 600
pF1KA0 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
520 530 540 550 560 570
610 620 630 640 650 660
pF1KA0 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
580 590 600 610 620 630
670 680 690 700 710 720
pF1KA0 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
640 650 660 670 680 690
730 740 750 760 770 780
pF1KA0 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
700 710 720 730 740 750
790 800 810 820 830 840
pF1KA0 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
:::::::::::::: ::::::::::::::::::::::::::::::::::::::
CCDS54 PEESRDITRPSRPA--------DLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
760 770 780 790 800
850 860 870 880 890 900
pF1KA0 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
810 820 830 840 850 860
910 920 930 940 950 960
pF1KA0 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
870 880 890 900 910 920
970 980 990 1000 1010 1020
pF1KA0 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
930 940 950 960 970 980
1030 1040 1050 1060 1070 1080
pF1KA0 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
990 1000 1010 1020 1030 1040
1090 1100 1110 1120 1130 1140
pF1KA0 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
1050 1060 1070 1080 1090 1100
1150 1160 1170 1180 1190 1200
pF1KA0 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
1110 1120 1130 1140 1150 1160
1210 1220 1230 1240 1250 1260
pF1KA0 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
1170 1180 1190 1200 1210 1220
1270 1280 1290 1300 1310 1320
pF1KA0 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
1230 1240 1250 1260 1270 1280
1330 1340 1350 1360
pF1KA0 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
::::::::::::::::::::::::::::::::::::::::
CCDS54 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
1290 1300 1310 1320
>>CCDS54678.1 TNIK gene_id:23043|Hs108|chr3 (1305 aa)
initn: 5073 init1: 5073 opt: 5232 Z-score: 1994.0 bits: 381.3 E(32554): 9.6e-105
Smith-Waterman score: 8522; 96.0% identity (96.0% similar) in 1360 aa overlap (1-1360:1-1305)
10 20 30 40 50 60
pF1KA0 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKE----
490 500 510 520 530
550 560 570 580 590 600
pF1KA0 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
:::::::::
CCDS54 ---------------------------------------------------IPHLVAVKS
540
610 620 630 640 650 660
pF1KA0 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
550 560 570 580 590 600
670 680 690 700 710 720
pF1KA0 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
610 620 630 640 650 660
730 740 750 760 770 780
pF1KA0 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
670 680 690 700 710 720
790 800 810 820 830 840
pF1KA0 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
730 740 750 760 770 780
850 860 870 880 890 900
pF1KA0 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
790 800 810 820 830 840
910 920 930 940 950 960
pF1KA0 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
850 860 870 880 890 900
970 980 990 1000 1010 1020
pF1KA0 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
910 920 930 940 950 960
1030 1040 1050 1060 1070 1080
pF1KA0 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
970 980 990 1000 1010 1020
1090 1100 1110 1120 1130 1140
pF1KA0 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
1030 1040 1050 1060 1070 1080
1150 1160 1170 1180 1190 1200
pF1KA0 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
1090 1100 1110 1120 1130 1140
1210 1220 1230 1240 1250 1260
pF1KA0 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
1150 1160 1170 1180 1190 1200
1270 1280 1290 1300 1310 1320
pF1KA0 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
1210 1220 1230 1240 1250 1260
1330 1340 1350 1360
pF1KA0 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
::::::::::::::::::::::::::::::::::::::::
CCDS54 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
1270 1280 1290 1300
>>CCDS54674.1 TNIK gene_id:23043|Hs108|chr3 (1276 aa)
initn: 8078 init1: 5073 opt: 5217 Z-score: 1988.4 bits: 380.2 E(32554): 1.9e-104
Smith-Waterman score: 8275; 93.8% identity (93.8% similar) in 1360 aa overlap (1-1360:1-1276)
10 20 30 40 50 60
pF1KA0 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
:::::::::::::::::::::::::: :::::
CCDS54 REQRRHYEEQMRREEERRRAEHEQEY-----------------------------KRKQL
430 440 450
490 500 510 520 530 540
pF1KA0 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKE----
460 470 480 490 500
550 560 570 580 590 600
pF1KA0 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
:::::::::
CCDS54 ---------------------------------------------------IPHLVAVKS
510
610 620 630 640 650 660
pF1KA0 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
520 530 540 550 560 570
670 680 690 700 710 720
pF1KA0 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
580 590 600 610 620 630
730 740 750 760 770 780
pF1KA0 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
640 650 660 670 680 690
790 800 810 820 830 840
pF1KA0 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
700 710 720 730 740 750
850 860 870 880 890 900
pF1KA0 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
760 770 780 790 800 810
910 920 930 940 950 960
pF1KA0 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
820 830 840 850 860 870
970 980 990 1000 1010 1020
pF1KA0 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
880 890 900 910 920 930
1030 1040 1050 1060 1070 1080
pF1KA0 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
940 950 960 970 980 990
1090 1100 1110 1120 1130 1140
pF1KA0 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
1000 1010 1020 1030 1040 1050
1150 1160 1170 1180 1190 1200
pF1KA0 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
1060 1070 1080 1090 1100 1110
1210 1220 1230 1240 1250 1260
pF1KA0 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
1120 1130 1140 1150 1160 1170
1270 1280 1290 1300 1310 1320
pF1KA0 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
1180 1190 1200 1210 1220 1230
1330 1340 1350 1360
pF1KA0 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
::::::::::::::::::::::::::::::::::::::::
CCDS54 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
1240 1250 1260 1270
>>CCDS54673.1 TNIK gene_id:23043|Hs108|chr3 (1268 aa)
initn: 6747 init1: 3742 opt: 5122 Z-score: 1952.7 bits: 373.6 E(32554): 1.9e-102
Smith-Waterman score: 8200; 93.2% identity (93.2% similar) in 1360 aa overlap (1-1360:1-1268)
10 20 30 40 50 60
pF1KA0 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
:::::::::::::::::::::::::: :::::
CCDS54 REQRRHYEEQMRREEERRRAEHEQEY-----------------------------KRKQL
430 440 450
490 500 510 520 530 540
pF1KA0 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKE----
460 470 480 490 500
550 560 570 580 590 600
pF1KA0 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
:::::::::
CCDS54 ---------------------------------------------------IPHLVAVKS
510
610 620 630 640 650 660
pF1KA0 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
520 530 540 550 560 570
670 680 690 700 710 720
pF1KA0 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
580 590 600 610 620 630
730 740 750 760 770 780
pF1KA0 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
640 650 660 670 680 690
790 800 810 820 830 840
pF1KA0 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
:::::::::::::: ::::::::::::::::::::::::::::::::::::::
CCDS54 PEESRDITRPSRPA--------DLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
700 710 720 730 740
850 860 870 880 890 900
pF1KA0 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
750 760 770 780 790 800
910 920 930 940 950 960
pF1KA0 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
810 820 830 840 850 860
970 980 990 1000 1010 1020
pF1KA0 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
870 880 890 900 910 920
1030 1040 1050 1060 1070 1080
pF1KA0 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
930 940 950 960 970 980
1090 1100 1110 1120 1130 1140
pF1KA0 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
990 1000 1010 1020 1030 1040
1150 1160 1170 1180 1190 1200
pF1KA0 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
1050 1060 1070 1080 1090 1100
1210 1220 1230 1240 1250 1260
pF1KA0 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
1110 1120 1130 1140 1150 1160
1270 1280 1290 1300 1310 1320
pF1KA0 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
1170 1180 1190 1200 1210 1220
1330 1340 1350 1360
pF1KA0 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
::::::::::::::::::::::::::::::::::::::::
CCDS54 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
1230 1240 1250 1260
>>CCDS54677.1 TNIK gene_id:23043|Hs108|chr3 (1297 aa)
initn: 7304 init1: 3742 opt: 5092 Z-score: 1941.2 bits: 371.5 E(32554): 8.3e-102
Smith-Waterman score: 8447; 95.4% identity (95.4% similar) in 1360 aa overlap (1-1360:1-1297)
10 20 30 40 50 60
pF1KA0 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKE----
490 500 510 520 530
550 560 570 580 590 600
pF1KA0 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
:::::::::
CCDS54 ---------------------------------------------------IPHLVAVKS
540
610 620 630 640 650 660
pF1KA0 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
550 560 570 580 590 600
670 680 690 700 710 720
pF1KA0 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
610 620 630 640 650 660
730 740 750 760 770 780
pF1KA0 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
670 680 690 700 710 720
790 800 810 820 830 840
pF1KA0 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
:::::::::::::: ::::::::::::::::::::::::::::::::::::::
CCDS54 PEESRDITRPSRPA--------DLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
730 740 750 760 770
850 860 870 880 890 900
pF1KA0 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
780 790 800 810 820 830
910 920 930 940 950 960
pF1KA0 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
840 850 860 870 880 890
970 980 990 1000 1010 1020
pF1KA0 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
900 910 920 930 940 950
1030 1040 1050 1060 1070 1080
pF1KA0 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
960 970 980 990 1000 1010
1090 1100 1110 1120 1130 1140
pF1KA0 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
1020 1030 1040 1050 1060 1070
1150 1160 1170 1180 1190 1200
pF1KA0 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
1080 1090 1100 1110 1120 1130
1210 1220 1230 1240 1250 1260
pF1KA0 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
1140 1150 1160 1170 1180 1190
1270 1280 1290 1300 1310 1320
pF1KA0 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
1200 1210 1220 1230 1240 1250
1330 1340 1350 1360
pF1KA0 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
::::::::::::::::::::::::::::::::::::::::
CCDS54 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
1260 1270 1280 1290
>>CCDS74546.1 MAP4K4 gene_id:9448|Hs108|chr2 (1273 aa)
initn: 4503 init1: 2092 opt: 2908 Z-score: 1118.2 bits: 219.2 E(32554): 5.8e-56
Smith-Waterman score: 5478; 64.7% identity (77.3% similar) in 1399 aa overlap (1-1360:1-1273)
10 20 30 40 50 60
pF1KA0 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
::.::::.:: .::::.::::::::::::.:::::::::::::::::::::::::::::
CCDS74 MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
::::::: ::::::::::::::::::::::::.::: :::::::::::::::.:::.:::
CCDS74 DEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
:::::::.::::: :::::::.::: :.::::::::::::::::::::::::::::::::
CCDS74 KGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
:::::::::::::::::::::::::::::::..::::: :::::::::::::::::::::
CCDS74 TVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
::::::::: :::::::::::: ::::.:::::. :::.::::.::::::::::::::::
CCDS74 ALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRI
250 260 270 280 290 300
310 320 330 340 350
pF1KA0 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEE--NDSGEPSSILNLPGESTLRRDFLRLQ
:::::::::.:::::::::::::::::::::: .. ::::::.:.::::::::::::::
CCDS74 QLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQ
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA0 LANKERSEALRRQQL--EQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELR
::::::::::::: ::: ::.::.:::::::::::::.:::::::::::::::.: :
CCDS74 QENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREAR
370 380 390 400 410 420
420 430 440 450
pF1KA0 KQQEREQRRHYEEQMRR-----------------EEERRRAEHEQEYIRRQLEEEQRQLE
.::::::::. .:. :: :::.::.:.::::::::::::::.::
CCDS74 RQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLE
430 440 450 460 470 480
460 470 480 490 500 510
pF1KA0 ILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEK--KP
.::::::.:::.::. .:. ::..: : .. ::
CCDS74 VLQQQLLQEQAMLLHDHRRPHP----------------------QHSQQPPPPQQERSKP
490 500 510
520 530 540 550 560 570
pF1KA0 LYHYKEGMSPSEKPAWAKEVEERSRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQ
.: : . : :.:::.: : . .::: : ..:. .: .: :::::: .: .
CCDS74 SFHAPEPKAHYEPADRAREVEDRFRKTNHSSPEAQSKQTGRVLEPPVPSRSESFS-NGNS
520 530 540 550 560 570
580 590 600 610 620 630
pF1KA0 PARTPPMLRPVDPQIPHLVAVKSQGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPR
. : . ::..::.: : . :..:.:. .: : .: :: .
CCDS74 ESVHPALQRPAEPQVP--VRTTSRSPVLSRRDS----PLQG-SG---------------Q
580 590 600 610
640 650 660 670 680 690
pF1KA0 QNSDPTSENPPLPTRIEKFDRSSWLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGP
:::. ..: . :: : : : :. .: ::.::
CCDS74 QNSQAGQRNS--TSSIEP--RLLWERVEKLVP------------------RPGSGS----
620 630 640
700 710 720 730 740 750
pF1KA0 RLGSQPIRASNPDLRRTEPILESPLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSER
:::::.:.: : ::.::::.::.::
CCDS74 ----------------------------SSGSSNSGSQP--------GSHPGSQSGSGER
650 660 670
760 770 780 790 800 810
pF1KA0 TRVRANSKSEGSPVLPHEPAKVKPEESRDITRPSRPASYKKAIDEDLTALAKELRELRIE
:::..::::::: : : :::..... :: .:: :::::::::: .
CCDS74 FRVRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPA--------DLTALAKELRAV---
680 690 700 710 720
820 830 840 850 860 870
pF1KA0 ETNRPMKKVTDYSSSSEESESSEEEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNV
: :: .:::::::::::: ...::..: :.: : ... . : . ...: .:
CCDS74 EDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNGETESV
730 740 750 760 770 780
880 890 900 910 920 930
pF1KA0 GMVGTHG-LETSHADSFSGSISREGTLMIRETSGEKKRSGHSDSNGFAGHINL-PDLVQQ
. .: .:. : . :.::::..:... ..::..: .::::::.:.: :::.::
CCDS74 KTMIVHDDVESEPA----MTPSKEGTLIVRQSTVDQKRASHHESNGFAGRIHLLPDLLQQ
790 800 810 820 830
940 950 960 970 980
pF1KA0 SHSPAGTPTEGLGRVSTHSQEMDSGT--------EYGMGSST------KASFTPFVDPRV
::: . . : . : . :. : : .::: ..:::::.:::.
CCDS74 SHSSSTSSTSSSPSSSQPTPTMSPQTPQDKLTANETQSASSTLQKHKSSSSFTPFIDPRL
840 850 860 870 880 890
990 1000 1010 1020 1030 1040
pF1KA0 YQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKISVVNVNPTNIRPHSDTPEIRK
: ::.. .... :. . .: : . . .:: ::::::::: ::.::::::::
CCDS74 LQISPSS----GTTVTSVVGFSCDGMRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRK
900 910 920 930 940 950
1050 1060 1070 1080 1090 1100
pF1KA0 YKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYNLINRRRFQQMDVLEGLNVLV
::::::::::::::::::::::::.:::::::::::::: ::::::::::::::::::::
CCDS74 YKKRFNSEILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLV
960 970 980 990 1000 1010
1110 1120 1130 1140 1150 1160
pF1KA0 TISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGDLEGCIHYKVVKYERIKFLVIA
::::::.::::::::::::.:::::::::::::: ::::::::.::::::::::::::::
CCDS74 TISGKKDKLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIA
1020 1030 1040 1050 1060 1070
1170 1180 1190 1200 1210 1220
pF1KA0 LKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVEEGQRLKVIFGSHTGFHVIDVD
::..::.:::::::::::::::::..: :::::::::::::::::::.:: .:::..:::
CCDS74 LKSSVEVYAWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVD
1080 1090 1100 1110 1120 1130
1230 1240 1250 1260 1270 1280
pF1KA0 SGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYEDEGVYVNTYGRITKDVVLQWGE
::. ::::.:.::: .: ::::.:::.:::::.:::::::::::::::::::::::::::
CCDS74 SGSVYDIYLPTHIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGE
1140 1150 1160 1170 1180 1190
1290 1300 1310 1320 1330 1340
pF1KA0 MPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRS
::::::::.::: :::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 MPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRS
1200 1210 1220 1230 1240 1250
1350 1360
pF1KA0 GGSSQVFFMTLNRNSMMNW
::::::.::::.:.:...:
CCDS74 GGSSQVYFMTLGRTSLLSW
1260 1270
>>CCDS82487.1 MAP4K4 gene_id:9448|Hs108|chr2 (1165 aa)
initn: 4514 init1: 2088 opt: 2791 Z-score: 1074.7 bits: 211.0 E(32554): 1.5e-53
Smith-Waterman score: 5041; 63.1% identity (74.2% similar) in 1380 aa overlap (1-1360:1-1165)
10 20 30 40 50 60
pF1KA0 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
::.::::.:: .::::.::::::::::::.:::::::::::::::::::::::::::::
CCDS82 MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
::::::: ::::::::::::::::::::::::.::: :::::::::::::::.:::.:::
CCDS82 DEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
:::::::.::::: :::::::.::: :.::::::::::::::::::::::::::::::::
CCDS82 KGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
:::::::::::::::::::::::::::::::..::::: :::::::::::::::::::::
CCDS82 TVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
::::::::: :::::::::::: ::::.:::::. :::.::::.::::::::::::::::
CCDS82 ALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRI
250 260 270 280 290 300
310 320 330 340 350
pF1KA0 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEE--NDSGEPSSILNLPGESTLRRDFLRLQ
:::::::::.:::::::::::::::::::::: .. ::::::.:.::::::::::::::
CCDS82 QLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQ
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA0 LANKERSEALRRQQL--EQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELR
::::::::::::: ::: ::.::.:::::::::::::.:::::::::::::::.: :
CCDS82 QENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREAR
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA0 KQQEREQRRHYEEQMRREEE--RRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLE
.::::::::. .:. :: :: ::: :.:. ::. :::.:..: .:: :
CCDS82 RQQEREQRRREQEEKRRLEELERRRKEEEE---RRRAEEEKRRVE-------REQ----E
430 440 450 460
480 490 500 510 520 530
pF1KA0 YKRKQLEE-QRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAW
: :.:::: ::. : ::.:: ::. .:. .:.:
CCDS82 YIRRQLEEEQRHLEVLQQQLLQEQAMLLH-DHRR--------------------------
470 480 490
540 550 560 570 580 590
pF1KA0 AKEVEERSRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIP
:: : .:. :: :: ::
CCDS82 ------------------PH-----------PQHSQ-------QP---PP------PQ--
500 510
600 610 620 630 640 650
pF1KA0 HLVAVKSQGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRI
:: : :. . : ..
CCDS82 -----------------------------QE--------------RSKPSFHAPEPKAHY
520
660 670 680 690 700 710
pF1KA0 EKFDRSSWLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRR
: ::. .:: :::: ::.:.:..:: .:: :.: .:.. .
CCDS82 EPADRAR----------EVPVRTTSRSPVLSRRDSPLQGS------GQQNSQAGQRNSTS
530 540 550 560 570
720 730 740 750 760
pF1KA0 TEPIL-----ESPLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEG
:: : :. . : .:::::.::. .::: ::.::::.::.:: :::..:::::
CCDS82 IEPRLLWERVEKLVPRPGSGSSSGSSNSGSQP----GSHPGSQSGSGERFRVRSSSKSEG
580 590 600 610 620
770 780 790 800 810 820
pF1KA0 SPVLPHEPAKVKPEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTD
:: : : :::..... :: .::. . :::::::::: . : :: .::::
CCDS82 SPSQRLENAVKKPEDKKEVFRPLKPAG-----EVDLTALAKELRAV---EDVRPPHKVTD
630 640 650 660 670 680
830 840 850 860 870 880
pF1KA0 YSSSSEESESSEEEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETS
:::::::: ...::..: :.: :..:. : : : .
CCDS82 YSSSSEESGTTDEEDDDVEQE--------------------GADES-------TSGPEDT
690 700 710
890 900 910 920 930 940
pF1KA0 HADSFSGSISREGTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLG
.: : : ..: .: :: . : :.: .. :: ::..
CCDS82 RAAS-SLNLS-NG-----ETESVKTMIVHDDVES---------------EPAMTPSKEGT
720 730 740 750
950 960 970 980 990 1000
pF1KA0 RVSTHSQEMDSGTEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLR
. ..: .: . .:: :::::.:::. : ::.. .... :. . .:
CCDS82 LIVRQTQSASSTLQKHKSSS---SFTPFIDPRLLQISPSS----GTTVTSVVGFSCDGMR
760 770 780 790 800
1010 1020 1030 1040 1050 1060
pF1KA0 QEQAKLNEARKISVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGL
: . . .:: ::::::::: ::.::::::::::::::::::::::::::::::::.::
CCDS82 PEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSEILCAALWGVNLLVGTESGL
810 820 830 840 850 860
1070 1080 1090 1100 1110 1120
pF1KA0 MLLDRSGQGKVYNLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPE
:::::::::::: ::::::::::::::::::::::::::.::::::::::::.:::::::
CCDS82 MLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKDKLRVYYLSWLRNKILHNDPE
870 880 890 900 910 920
1130 1140 1150 1160 1170 1180
pF1KA0 VEKKQGWITVGDLEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADL
::::::: ::::::::.::::::::::::::::::..::.:::::::::::::::::..:
CCDS82 VEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFGEL
930 940 950 960 970 980
1190 1200 1210 1220 1230 1240
pF1KA0 QHKPLLVDLTVEEGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGN--------ITP
:::::::::::::::::::.:: .:::..:::::. ::::.:.:.. : : :
CCDS82 VHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIYLPTHVRKNPHSMIQCSIKP
990 1000 1010 1020 1030 1040
1250 1260 1270 1280 1290 1300
pF1KA0 HAIVILPKTDGMEMLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEK
:::.:::.:::::.:::::::::::::::::::::::::::::::::::.::: ::::::
CCDS82 HAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIRSNQTMGWGEK
1050 1060 1070 1080 1090 1100
1310 1320 1330 1340 1350 1360
pF1KA0 AIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
:::::::::::::::::::::::::::::::::::::::::::::::.::::.:.:...:
CCDS82 AIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLGRTSLLSW
1110 1120 1130 1140 1150 1160
1360 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 09:41:26 2016 done: Thu Nov 3 09:41:27 2016
Total Scan time: 6.530 Total Display time: 0.730
Function used was FASTA [36.3.4 Apr, 2011]