Result of FASTA (omim) for
pF1KA0542
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0542, 1211 aa
1>>>pF1KA0542 1211 - 1211 aa - 1211 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.5415+/-0.000519; mu= -17.9897+/- 0.032
mean_var=385.2008+/-78.872, 0's: 0 Z-trim(118.4): 57 B-trim: 277 in 1/53
Lambda= 0.065348
statistics sampled from 31167 (31223) to 31167 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.692), E-opt: 0.2 (0.366), width: 16
Scan time: 15.580
The best scores are: opt bits E(85289)
XP_016884640 (OMIM: 612765) PREDICTED: protein SFI (1211) 8346 802.2 0
NP_055590 (OMIM: 612765) protein SFI1 homolog isof (1211) 8346 802.2 0
XP_016884633 (OMIM: 612765) PREDICTED: protein SFI (1240) 8136 782.4 0
XP_016884628 (OMIM: 612765) PREDICTED: protein SFI (1243) 8120 780.9 0
XP_016884632 (OMIM: 612765) PREDICTED: protein SFI (1243) 8120 780.9 0
NP_001245254 (OMIM: 612765) protein SFI1 homolog i (1187) 7613 733.1 2.5e-210
XP_016884643 (OMIM: 612765) PREDICTED: protein SFI (1187) 7613 733.1 2.5e-210
XP_016884645 (OMIM: 612765) PREDICTED: protein SFI (1129) 7603 732.2 4.6e-210
XP_016884634 (OMIM: 612765) PREDICTED: protein SFI (1216) 7403 713.3 2.3e-204
XP_016884644 (OMIM: 612765) PREDICTED: protein SFI (1158) 7393 712.4 4.3e-204
XP_016884637 (OMIM: 612765) PREDICTED: protein SFI (1219) 7387 711.8 6.6e-204
XP_016884636 (OMIM: 612765) PREDICTED: protein SFI (1219) 7387 711.8 6.6e-204
XP_016884639 (OMIM: 612765) PREDICTED: protein SFI (1218) 6412 619.9 3.1e-176
XP_016884638 (OMIM: 612765) PREDICTED: protein SFI (1218) 6412 619.9 3.1e-176
XP_016884631 (OMIM: 612765) PREDICTED: protein SFI (1250) 6186 598.6 8.2e-170
XP_006724453 (OMIM: 612765) PREDICTED: protein SFI (1160) 5862 568.0 1.2e-160
NP_001245255 (OMIM: 612765) protein SFI1 homolog i (1160) 5862 568.0 1.2e-160
NP_001007468 (OMIM: 612765) protein SFI1 homolog i (1242) 5862 568.1 1.3e-160
XP_005261925 (OMIM: 612765) PREDICTED: protein SFI (1271) 5652 548.3 1.2e-154
XP_016884630 (OMIM: 612765) PREDICTED: protein SFI (1228) 5643 547.4 2.1e-154
XP_016884642 (OMIM: 612765) PREDICTED: protein SFI (1192) 5636 546.7 3.2e-154
XP_011528877 (OMIM: 612765) PREDICTED: protein SFI (1274) 5636 546.8 3.4e-154
XP_011528882 (OMIM: 612765) PREDICTED: protein SFI (1260) 5626 545.8 6.5e-154
XP_016884629 (OMIM: 612765) PREDICTED: protein SFI (1236) 4893 476.7 4e-133
XP_016884641 (OMIM: 612765) PREDICTED: protein SFI (1178) 4883 475.7 7.4e-133
XP_016884651 (OMIM: 612765) PREDICTED: protein SFI ( 632) 3873 380.4 2e-104
XP_016884650 (OMIM: 612765) PREDICTED: protein SFI ( 635) 3857 378.9 5.6e-104
XP_011528879 (OMIM: 612765) PREDICTED: protein SFI (1267) 3692 363.5 5e-99
XP_011528878 (OMIM: 612765) PREDICTED: protein SFI (1267) 3692 363.5 5e-99
NP_001245256 (OMIM: 612765) protein SFI1 homolog i (1148) 3586 353.5 4.7e-96
XP_011528883 (OMIM: 612765) PREDICTED: protein SFI (1259) 3159 313.2 6.7e-84
XP_011528876 (OMIM: 612765) PREDICTED: protein SFI (1288) 3153 312.7 1e-83
XP_011528885 (OMIM: 612765) PREDICTED: protein SFI (1209) 3142 311.6 2e-83
XP_011528884 (OMIM: 612765) PREDICTED: protein SFI (1209) 3142 311.6 2e-83
XP_011528881 (OMIM: 612765) PREDICTED: protein SFI (1262) 3142 311.6 2e-83
XP_011528873 (OMIM: 612765) PREDICTED: protein SFI (1291) 3142 311.6 2.1e-83
XP_011528872 (OMIM: 612765) PREDICTED: protein SFI (1291) 3142 311.6 2.1e-83
XP_016884647 (OMIM: 612765) PREDICTED: protein SFI ( 909) 3125 310.0 4.6e-83
XP_016884646 (OMIM: 612765) PREDICTED: protein SFI (1105) 3118 309.3 8.6e-83
XP_016884635 (OMIM: 612765) PREDICTED: protein SFI (1204) 3009 299.1 1.2e-79
XP_016884648 (OMIM: 612765) PREDICTED: protein SFI ( 724) 1444 151.4 1.9e-35
XP_011528889 (OMIM: 612765) PREDICTED: protein SFI ( 724) 1444 151.4 1.9e-35
XP_016884649 (OMIM: 612765) PREDICTED: protein SFI ( 652) 1363 143.8 3.5e-33
>>XP_016884640 (OMIM: 612765) PREDICTED: protein SFI1 ho (1211 aa)
initn: 8346 init1: 8346 opt: 8346 Z-score: 4270.4 bits: 802.2 E(85289): 0
Smith-Waterman score: 8346; 99.8% identity (99.9% similar) in 1211 aa overlap (1-1211:1-1211)
10 20 30 40 50 60
pF1KA0 MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 ELPSTSHLVQYRGTHTCTRQGRLRELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELPSTSHLVQYRGTHTCTRQGRLRELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 RVKRQQNEMAERFHHVTVLQIHFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK
:::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::
XP_016 RVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 HYMLLCAEEAAQFEMAEEHHRHSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HYMLLCAEEAAQFEMAEEHHRHSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 LLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARAT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 RFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 WQTVACAHHRHGRLKKAFCLWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQWRECLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WQTVACAHHRHGRLKKAFCLWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQWRECLAL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 RGAERQKLMRADLHHQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQLLRGALRRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGAERQKLMRADLHHQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQLLRGALRRW
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 KENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMYYRQQEDCAIWEAQKVLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMYYRQQEDCAIWEAQKVLDR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 GCLRTWFQRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHHLQCVRKRLLHRQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCLRTWFQRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHHLQCVRKRLLHRQS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 TQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFSLQAKVWATWLAFVLERRRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFSLQAKVWATWLAFVLERRRKK
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 ARLQWALQAYQGQLLQEGATRLLRFAASMKASRQQLQAQQQVQAAHSLHRAVRRCATLWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARLQWALQAYQGQLLQEGATRLLRFAASMKASRQQLQAQQQVQAAHSLHRAVRRCATLWK
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 QKVLGRGGKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKVLGRGGKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLAA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 EEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAP
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 TALVPHSPLPGALSSAPGPKQPPTASTGPELLLLPPSSFMPCGAAAPARVSAQRATPRDK
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
XP_016 TALVPHSPLPGALSSAPGPKQPPTASTGPELLLLPLSSFMPCGAAAPARVSAQRATPRDK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 PPVPSSLASVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAELEEIQQQLLHYQTTKQNLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPVPSSLASVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAELEEIQQQLLHYQTTKQNLW
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 SCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELEQVEMQIQLLAEELQAQRQPIGACV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELEQVEMQIQLLAEELQAQRQPIGACV
1150 1160 1170 1180 1190 1200
1210
pF1KA0 ARIQALRQALC
:::::::::::
XP_016 ARIQALRQALC
1210
>>NP_055590 (OMIM: 612765) protein SFI1 homolog isoform (1211 aa)
initn: 8346 init1: 8346 opt: 8346 Z-score: 4270.4 bits: 802.2 E(85289): 0
Smith-Waterman score: 8346; 99.8% identity (99.9% similar) in 1211 aa overlap (1-1211:1-1211)
10 20 30 40 50 60
pF1KA0 MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 ELPSTSHLVQYRGTHTCTRQGRLRELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ELPSTSHLVQYRGTHTCTRQGRLRELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 RVKRQQNEMAERFHHVTVLQIHFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK
:::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::
NP_055 RVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 HYMLLCAEEAAQFEMAEEHHRHSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 HYMLLCAEEAAQFEMAEEHHRHSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 LLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARAT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 RFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 WQTVACAHHRHGRLKKAFCLWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQWRECLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 WQTVACAHHRHGRLKKAFCLWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQWRECLAL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 RGAERQKLMRADLHHQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQLLRGALRRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RGAERQKLMRADLHHQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQLLRGALRRW
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 KENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMYYRQQEDCAIWEAQKVLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMYYRQQEDCAIWEAQKVLDR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 GCLRTWFQRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHHLQCVRKRLLHRQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GCLRTWFQRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHHLQCVRKRLLHRQS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 TQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFSLQAKVWATWLAFVLERRRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFSLQAKVWATWLAFVLERRRKK
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 ARLQWALQAYQGQLLQEGATRLLRFAASMKASRQQLQAQQQVQAAHSLHRAVRRCATLWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ARLQWALQAYQGQLLQEGATRLLRFAASMKASRQQLQAQQQVQAAHSLHRAVRRCATLWK
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 QKVLGRGGKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QKVLGRGGKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLAA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 EEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAP
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 TALVPHSPLPGALSSAPGPKQPPTASTGPELLLLPPSSFMPCGAAAPARVSAQRATPRDK
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
NP_055 TALVPHSPLPGALSSAPGPKQPPTASTGPELLLLPLSSFMPCGAAAPARVSAQRATPRDK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 PPVPSSLASVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAELEEIQQQLLHYQTTKQNLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PPVPSSLASVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAELEEIQQQLLHYQTTKQNLW
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 SCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELEQVEMQIQLLAEELQAQRQPIGACV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELEQVEMQIQLLAEELQAQRQPIGACV
1150 1160 1170 1180 1190 1200
1210
pF1KA0 ARIQALRQALC
:::::::::::
NP_055 ARIQALRQALC
1210
>>XP_016884633 (OMIM: 612765) PREDICTED: protein SFI1 ho (1240 aa)
initn: 8511 init1: 8136 opt: 8136 Z-score: 4163.3 bits: 782.4 E(85289): 0
Smith-Waterman score: 8278; 97.5% identity (97.6% similar) in 1240 aa overlap (1-1211:1-1240)
10 20 30 40 50 60
pF1KA0 MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 ELPSTSHLVQYRGTHTCTRQGRLRELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELPSTSHLVQYRGTHTCTRQGRLRELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 RVKRQQNEMAERFHHVTVLQIHFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK
:::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::
XP_016 RVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 HYMLLCAEEAAQFEMAEEHHRHSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HYMLLCAEEAAQFEMAEEHHRHSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 LLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARAT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 RFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 WQTVACAHHRHGRLKKAFCLWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQWRECLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WQTVACAHHRHGRLKKAFCLWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQWRECLAL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 RGAERQKLMRADLHHQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQLLRGALRRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGAERQKLMRADLHHQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQLLRGALRRW
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 KENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMYYRQQEDCAIWEAQKVLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMYYRQQEDCAIWEAQKVLDR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 GCLRTWFQRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHHLQCVRKRLLHRQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCLRTWFQRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHHLQCVRKRLLHRQS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 TQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFSLQAKVWATWLAFVLERRRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFSLQAKVWATWLAFVLERRRKK
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 ARLQWALQAYQGQLLQEGATRLLRFAASMKASRQQLQAQQQVQAAHSLHRAVRRCATLWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARLQWALQAYQGQLLQEGATRLLRFAASMKASRQQLQAQQQVQAAHSLHRAVRRCATLWK
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 QKVLGRGGKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKVLGRGGKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLAA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 EEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAP
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 TALVPHSPLPGALSSAPGPKQPPTASTGPELLLLPPSSFMPCGAAAPARVSAQRATPRDK
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
XP_016 TALVPHSPLPGALSSAPGPKQPPTASTGPELLLLPLSSFMPCGAAAPARVSAQRATPRDK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 PPVPSSLASVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAELEEIQQQLLHYQTTKQNLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPVPSSLASVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAELEEIQQQLLHYQTTKQNLW
1090 1100 1110 1120 1130 1140
1150 1160 1170
pF1KA0 SCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELEQV----------------------
::::::::::::::::::::::::::::::::::::::
XP_016 SCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELEQVRPQAIPRCPWGRPGLCSLSALP
1150 1160 1170 1180 1190 1200
1180 1190 1200 1210
pF1KA0 -------EMQIQLLAEELQAQRQPIGACVARIQALRQALC
:::::::::::::::::::::::::::::::::
XP_016 VPPWPQVEMQIQLLAEELQAQRQPIGACVARIQALRQALC
1210 1220 1230 1240
>>XP_016884628 (OMIM: 612765) PREDICTED: protein SFI1 ho (1243 aa)
initn: 8510 init1: 6893 opt: 8120 Z-score: 4155.1 bits: 780.9 E(85289): 0
Smith-Waterman score: 8262; 97.3% identity (97.3% similar) in 1243 aa overlap (1-1211:1-1243)
10 20 30 40 50 60
pF1KA0 MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 ELPSTSHLVQYRGTHTCTRQGRLRELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELPSTSHLVQYRGTHTCTRQGRLRELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 RVKRQQNEMAERFHHVTVLQIHFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK
:::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::
XP_016 RVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 HYMLLCAEEAAQFEMAEEHHRHSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HYMLLCAEEAAQFEMAEEHHRHSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 LLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARAT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 RFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 WQTVACAHHRHGRLKKAFCLWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQWRECLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WQTVACAHHRHGRLKKAFCLWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQWRECLAL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 RGAERQKLMRADLHHQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQLLRGALRRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGAERQKLMRADLHHQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQLLRGALRRW
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 KENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMYYRQQEDCAIWEAQKVLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMYYRQQEDCAIWEAQKVLDR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 GCLRTWFQRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHHLQCVRKRLLHRQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCLRTWFQRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHHLQCVRKRLLHRQS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 TQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFSLQAKVWATWLAFVLERRRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFSLQAKVWATWLAFVLERRRKK
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 ARLQWALQAYQGQLLQEGATRLLRFAASMKASRQQLQAQQQVQAAHSLHRAVRRCATLWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARLQWALQAYQGQLLQEGATRLLRFAASMKASRQQLQAQQQVQAAHSLHRAVRRCATLWK
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 QKVLGRGGKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKVLGRGGKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLAA
910 920 930 940 950 960
970 980 990 1000 1010
pF1KA0 EEPHALELNTAHSARKQPRRPHFLLEPAQSQR---PQKPQEHGLGMAQPAAPSLTRPFLA
:::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
XP_016 EEPHALELNTAHSARKQPRRPHFLLEPAQSQRSLGPQKPQEHGLGMAQPAAPSLTRPFLA
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KA0 EAPTALVPHSPLPGALSSAPGPKQPPTASTGPELLLLPPSSFMPCGAAAPARVSAQRATP
:::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::
XP_016 EAPTALVPHSPLPGALSSAPGPKQPPTASTGPELLLLPLSSFMPCGAAAPARVSAQRATP
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KA0 RDKPPVPSSLASVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAELEEIQQQLLHYQTTKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDKPPVPSSLASVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAELEEIQQQLLHYQTTKQ
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170
pF1KA0 NLWSCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELEQV-------------------
:::::::::::::::::::::::::::::::::::::::::
XP_016 NLWSCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELEQVRPQAIPRCPWGRPGLCSLS
1150 1160 1170 1180 1190 1200
1180 1190 1200 1210
pF1KA0 ----------EMQIQLLAEELQAQRQPIGACVARIQALRQALC
:::::::::::::::::::::::::::::::::
XP_016 ALPVPPWPQVEMQIQLLAEELQAQRQPIGACVARIQALRQALC
1210 1220 1230 1240
>>XP_016884632 (OMIM: 612765) PREDICTED: protein SFI1 ho (1243 aa)
initn: 8510 init1: 6893 opt: 8120 Z-score: 4155.1 bits: 780.9 E(85289): 0
Smith-Waterman score: 8262; 97.3% identity (97.3% similar) in 1243 aa overlap (1-1211:1-1243)
10 20 30 40 50 60
pF1KA0 MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 ELPSTSHLVQYRGTHTCTRQGRLRELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELPSTSHLVQYRGTHTCTRQGRLRELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 RVKRQQNEMAERFHHVTVLQIHFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK
:::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::
XP_016 RVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 HYMLLCAEEAAQFEMAEEHHRHSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HYMLLCAEEAAQFEMAEEHHRHSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 LLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARAT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 RFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 WQTVACAHHRHGRLKKAFCLWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQWRECLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WQTVACAHHRHGRLKKAFCLWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQWRECLAL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 RGAERQKLMRADLHHQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQLLRGALRRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGAERQKLMRADLHHQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQLLRGALRRW
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 KENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMYYRQQEDCAIWEAQKVLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMYYRQQEDCAIWEAQKVLDR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 GCLRTWFQRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHHLQCVRKRLLHRQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCLRTWFQRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHHLQCVRKRLLHRQS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 TQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFSLQAKVWATWLAFVLERRRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFSLQAKVWATWLAFVLERRRKK
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 ARLQWALQAYQGQLLQEGATRLLRFAASMKASRQQLQAQQQVQAAHSLHRAVRRCATLWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARLQWALQAYQGQLLQEGATRLLRFAASMKASRQQLQAQQQVQAAHSLHRAVRRCATLWK
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 QKVLGRGGKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKVLGRGGKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLAA
910 920 930 940 950 960
970 980 990 1000 1010
pF1KA0 EEPHALELNTAHSARKQPRRPHFLLEPAQSQR---PQKPQEHGLGMAQPAAPSLTRPFLA
:::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
XP_016 EEPHALELNTAHSARKQPRRPHFLLEPAQSQRSLGPQKPQEHGLGMAQPAAPSLTRPFLA
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KA0 EAPTALVPHSPLPGALSSAPGPKQPPTASTGPELLLLPPSSFMPCGAAAPARVSAQRATP
:::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::
XP_016 EAPTALVPHSPLPGALSSAPGPKQPPTASTGPELLLLPLSSFMPCGAAAPARVSAQRATP
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KA0 RDKPPVPSSLASVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAELEEIQQQLLHYQTTKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDKPPVPSSLASVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAELEEIQQQLLHYQTTKQ
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170
pF1KA0 NLWSCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELEQV-------------------
:::::::::::::::::::::::::::::::::::::::::
XP_016 NLWSCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELEQVRPQAIPRCPWGRPGLCSLS
1150 1160 1170 1180 1190 1200
1180 1190 1200 1210
pF1KA0 ----------EMQIQLLAEELQAQRQPIGACVARIQALRQALC
:::::::::::::::::::::::::::::::::
XP_016 ALPVPPWPQVEMQIQLLAEELQAQRQPIGACVARIQALRQALC
1210 1220 1230 1240
>>NP_001245254 (OMIM: 612765) protein SFI1 homolog isofo (1187 aa)
initn: 7613 init1: 7613 opt: 7613 Z-score: 3897.1 bits: 733.1 E(85289): 2.5e-210
Smith-Waterman score: 8118; 97.9% identity (97.9% similar) in 1211 aa overlap (1-1211:1-1187)
10 20 30 40 50 60
pF1KA0 MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 ELPSTSHLVQYRGTHTCTRQGRLRELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRL
::::::::::::::::::::::::::::: :::::::
NP_001 ELPSTSHLVQYRGTHTCTRQGRLRELRIR------------------------FYYEQRL
70 80 90
130 140 150 160 170 180
pF1KA0 LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV
100 110 120 130 140 150
190 200 210 220 230 240
pF1KA0 HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL
160 170 180 190 200 210
250 260 270 280 290 300
pF1KA0 HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR
220 230 240 250 260 270
310 320 330 340 350 360
pF1KA0 RVKRQQNEMAERFHHVTVLQIHFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK
:::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::
NP_001 RVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK
280 290 300 310 320 330
370 380 390 400 410 420
pF1KA0 HYMLLCAEEAAQFEMAEEHHRHSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HYMLLCAEEAAQFEMAEEHHRHSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIA
340 350 360 370 380 390
430 440 450 460 470 480
pF1KA0 LLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARAT
400 410 420 430 440 450
490 500 510 520 530 540
pF1KA0 RFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQE
460 470 480 490 500 510
550 560 570 580 590 600
pF1KA0 WQTVACAHHRHGRLKKAFCLWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQWRECLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WQTVACAHHRHGRLKKAFCLWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQWRECLAL
520 530 540 550 560 570
610 620 630 640 650 660
pF1KA0 RGAERQKLMRADLHHQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQLLRGALRRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGAERQKLMRADLHHQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQLLRGALRRW
580 590 600 610 620 630
670 680 690 700 710 720
pF1KA0 KENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMYYRQQEDCAIWEAQKVLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMYYRQQEDCAIWEAQKVLDR
640 650 660 670 680 690
730 740 750 760 770 780
pF1KA0 GCLRTWFQRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHHLQCVRKRLLHRQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GCLRTWFQRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHHLQCVRKRLLHRQS
700 710 720 730 740 750
790 800 810 820 830 840
pF1KA0 TQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFSLQAKVWATWLAFVLERRRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFSLQAKVWATWLAFVLERRRKK
760 770 780 790 800 810
850 860 870 880 890 900
pF1KA0 ARLQWALQAYQGQLLQEGATRLLRFAASMKASRQQLQAQQQVQAAHSLHRAVRRCATLWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARLQWALQAYQGQLLQEGATRLLRFAASMKASRQQLQAQQQVQAAHSLHRAVRRCATLWK
820 830 840 850 860 870
910 920 930 940 950 960
pF1KA0 QKVLGRGGKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKVLGRGGKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLAA
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KA0 EEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAP
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KA0 TALVPHSPLPGALSSAPGPKQPPTASTGPELLLLPPSSFMPCGAAAPARVSAQRATPRDK
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
NP_001 TALVPHSPLPGALSSAPGPKQPPTASTGPELLLLPLSSFMPCGAAAPARVSAQRATPRDK
1000 1010 1020 1030 1040 1050
1090 1100 1110 1120 1130 1140
pF1KA0 PPVPSSLASVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAELEEIQQQLLHYQTTKQNLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPVPSSLASVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAELEEIQQQLLHYQTTKQNLW
1060 1070 1080 1090 1100 1110
1150 1160 1170 1180 1190 1200
pF1KA0 SCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELEQVEMQIQLLAEELQAQRQPIGACV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELEQVEMQIQLLAEELQAQRQPIGACV
1120 1130 1140 1150 1160 1170
1210
pF1KA0 ARIQALRQALC
:::::::::::
NP_001 ARIQALRQALC
1180
>>XP_016884643 (OMIM: 612765) PREDICTED: protein SFI1 ho (1187 aa)
initn: 7613 init1: 7613 opt: 7613 Z-score: 3897.1 bits: 733.1 E(85289): 2.5e-210
Smith-Waterman score: 8118; 97.9% identity (97.9% similar) in 1211 aa overlap (1-1211:1-1187)
10 20 30 40 50 60
pF1KA0 MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 ELPSTSHLVQYRGTHTCTRQGRLRELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRL
::::::::::::::::::::::::::::: :::::::
XP_016 ELPSTSHLVQYRGTHTCTRQGRLRELRIR------------------------FYYEQRL
70 80 90
130 140 150 160 170 180
pF1KA0 LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV
100 110 120 130 140 150
190 200 210 220 230 240
pF1KA0 HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL
160 170 180 190 200 210
250 260 270 280 290 300
pF1KA0 HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR
220 230 240 250 260 270
310 320 330 340 350 360
pF1KA0 RVKRQQNEMAERFHHVTVLQIHFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK
:::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::
XP_016 RVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK
280 290 300 310 320 330
370 380 390 400 410 420
pF1KA0 HYMLLCAEEAAQFEMAEEHHRHSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HYMLLCAEEAAQFEMAEEHHRHSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIA
340 350 360 370 380 390
430 440 450 460 470 480
pF1KA0 LLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARAT
400 410 420 430 440 450
490 500 510 520 530 540
pF1KA0 RFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQE
460 470 480 490 500 510
550 560 570 580 590 600
pF1KA0 WQTVACAHHRHGRLKKAFCLWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQWRECLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WQTVACAHHRHGRLKKAFCLWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQWRECLAL
520 530 540 550 560 570
610 620 630 640 650 660
pF1KA0 RGAERQKLMRADLHHQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQLLRGALRRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGAERQKLMRADLHHQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQLLRGALRRW
580 590 600 610 620 630
670 680 690 700 710 720
pF1KA0 KENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMYYRQQEDCAIWEAQKVLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMYYRQQEDCAIWEAQKVLDR
640 650 660 670 680 690
730 740 750 760 770 780
pF1KA0 GCLRTWFQRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHHLQCVRKRLLHRQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCLRTWFQRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHHLQCVRKRLLHRQS
700 710 720 730 740 750
790 800 810 820 830 840
pF1KA0 TQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFSLQAKVWATWLAFVLERRRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFSLQAKVWATWLAFVLERRRKK
760 770 780 790 800 810
850 860 870 880 890 900
pF1KA0 ARLQWALQAYQGQLLQEGATRLLRFAASMKASRQQLQAQQQVQAAHSLHRAVRRCATLWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARLQWALQAYQGQLLQEGATRLLRFAASMKASRQQLQAQQQVQAAHSLHRAVRRCATLWK
820 830 840 850 860 870
910 920 930 940 950 960
pF1KA0 QKVLGRGGKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKVLGRGGKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLAA
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KA0 EEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAP
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KA0 TALVPHSPLPGALSSAPGPKQPPTASTGPELLLLPPSSFMPCGAAAPARVSAQRATPRDK
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
XP_016 TALVPHSPLPGALSSAPGPKQPPTASTGPELLLLPLSSFMPCGAAAPARVSAQRATPRDK
1000 1010 1020 1030 1040 1050
1090 1100 1110 1120 1130 1140
pF1KA0 PPVPSSLASVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAELEEIQQQLLHYQTTKQNLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPVPSSLASVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAELEEIQQQLLHYQTTKQNLW
1060 1070 1080 1090 1100 1110
1150 1160 1170 1180 1190 1200
pF1KA0 SCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELEQVEMQIQLLAEELQAQRQPIGACV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELEQVEMQIQLLAEELQAQRQPIGACV
1120 1130 1140 1150 1160 1170
1210
pF1KA0 ARIQALRQALC
:::::::::::
XP_016 ARIQALRQALC
1180
>>XP_016884645 (OMIM: 612765) PREDICTED: protein SFI1 ho (1129 aa)
initn: 7603 init1: 7603 opt: 7603 Z-score: 3892.3 bits: 732.2 E(85289): 4.6e-210
Smith-Waterman score: 7624; 93.1% identity (93.1% similar) in 1211 aa overlap (1-1211:1-1129)
10 20 30 40 50 60
pF1KA0 MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRR
:::::::::::::::::::::::::::::::
XP_016 MKNLLTEKCISSHNFHQKVIKQRMEKKVDSR-----------------------------
10 20 30
70 80 90 100 110 120
pF1KA0 ELPSTSHLVQYRGTHTCTRQGRLRELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRL
:::::::
XP_016 -----------------------------------------------------FYYEQRL
130 140 150 160 170 180
pF1KA0 LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV
40 50 60 70 80 90
190 200 210 220 230 240
pF1KA0 HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL
100 110 120 130 140 150
250 260 270 280 290 300
pF1KA0 HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR
160 170 180 190 200 210
310 320 330 340 350 360
pF1KA0 RVKRQQNEMAERFHHVTVLQIHFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK
:::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::
XP_016 RVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK
220 230 240 250 260 270
370 380 390 400 410 420
pF1KA0 HYMLLCAEEAAQFEMAEEHHRHSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HYMLLCAEEAAQFEMAEEHHRHSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIA
280 290 300 310 320 330
430 440 450 460 470 480
pF1KA0 LLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARAT
340 350 360 370 380 390
490 500 510 520 530 540
pF1KA0 RFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQE
400 410 420 430 440 450
550 560 570 580 590 600
pF1KA0 WQTVACAHHRHGRLKKAFCLWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQWRECLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WQTVACAHHRHGRLKKAFCLWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQWRECLAL
460 470 480 490 500 510
610 620 630 640 650 660
pF1KA0 RGAERQKLMRADLHHQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQLLRGALRRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGAERQKLMRADLHHQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQLLRGALRRW
520 530 540 550 560 570
670 680 690 700 710 720
pF1KA0 KENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMYYRQQEDCAIWEAQKVLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMYYRQQEDCAIWEAQKVLDR
580 590 600 610 620 630
730 740 750 760 770 780
pF1KA0 GCLRTWFQRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHHLQCVRKRLLHRQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCLRTWFQRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHHLQCVRKRLLHRQS
640 650 660 670 680 690
790 800 810 820 830 840
pF1KA0 TQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFSLQAKVWATWLAFVLERRRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFSLQAKVWATWLAFVLERRRKK
700 710 720 730 740 750
850 860 870 880 890 900
pF1KA0 ARLQWALQAYQGQLLQEGATRLLRFAASMKASRQQLQAQQQVQAAHSLHRAVRRCATLWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARLQWALQAYQGQLLQEGATRLLRFAASMKASRQQLQAQQQVQAAHSLHRAVRRCATLWK
760 770 780 790 800 810
910 920 930 940 950 960
pF1KA0 QKVLGRGGKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKVLGRGGKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLAA
820 830 840 850 860 870
970 980 990 1000 1010 1020
pF1KA0 EEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAP
880 890 900 910 920 930
1030 1040 1050 1060 1070 1080
pF1KA0 TALVPHSPLPGALSSAPGPKQPPTASTGPELLLLPPSSFMPCGAAAPARVSAQRATPRDK
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
XP_016 TALVPHSPLPGALSSAPGPKQPPTASTGPELLLLPLSSFMPCGAAAPARVSAQRATPRDK
940 950 960 970 980 990
1090 1100 1110 1120 1130 1140
pF1KA0 PPVPSSLASVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAELEEIQQQLLHYQTTKQNLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPVPSSLASVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAELEEIQQQLLHYQTTKQNLW
1000 1010 1020 1030 1040 1050
1150 1160 1170 1180 1190 1200
pF1KA0 SCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELEQVEMQIQLLAEELQAQRQPIGACV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELEQVEMQIQLLAEELQAQRQPIGACV
1060 1070 1080 1090 1100 1110
1210
pF1KA0 ARIQALRQALC
:::::::::::
XP_016 ARIQALRQALC
1120
>>XP_016884634 (OMIM: 612765) PREDICTED: protein SFI1 ho (1216 aa)
initn: 8345 init1: 7403 opt: 7403 Z-score: 3789.9 bits: 713.3 E(85289): 2.3e-204
Smith-Waterman score: 8050; 95.6% identity (95.6% similar) in 1240 aa overlap (1-1211:1-1216)
10 20 30 40 50 60
pF1KA0 MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 ELPSTSHLVQYRGTHTCTRQGRLRELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRL
::::::::::::::::::::::::::::: :::::::
XP_016 ELPSTSHLVQYRGTHTCTRQGRLRELRIR------------------------FYYEQRL
70 80 90
130 140 150 160 170 180
pF1KA0 LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV
100 110 120 130 140 150
190 200 210 220 230 240
pF1KA0 HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL
160 170 180 190 200 210
250 260 270 280 290 300
pF1KA0 HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR
220 230 240 250 260 270
310 320 330 340 350 360
pF1KA0 RVKRQQNEMAERFHHVTVLQIHFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK
:::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::
XP_016 RVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK
280 290 300 310 320 330
370 380 390 400 410 420
pF1KA0 HYMLLCAEEAAQFEMAEEHHRHSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HYMLLCAEEAAQFEMAEEHHRHSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIA
340 350 360 370 380 390
430 440 450 460 470 480
pF1KA0 LLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARAT
400 410 420 430 440 450
490 500 510 520 530 540
pF1KA0 RFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQE
460 470 480 490 500 510
550 560 570 580 590 600
pF1KA0 WQTVACAHHRHGRLKKAFCLWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQWRECLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WQTVACAHHRHGRLKKAFCLWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQWRECLAL
520 530 540 550 560 570
610 620 630 640 650 660
pF1KA0 RGAERQKLMRADLHHQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQLLRGALRRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGAERQKLMRADLHHQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQLLRGALRRW
580 590 600 610 620 630
670 680 690 700 710 720
pF1KA0 KENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMYYRQQEDCAIWEAQKVLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMYYRQQEDCAIWEAQKVLDR
640 650 660 670 680 690
730 740 750 760 770 780
pF1KA0 GCLRTWFQRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHHLQCVRKRLLHRQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCLRTWFQRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHHLQCVRKRLLHRQS
700 710 720 730 740 750
790 800 810 820 830 840
pF1KA0 TQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFSLQAKVWATWLAFVLERRRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFSLQAKVWATWLAFVLERRRKK
760 770 780 790 800 810
850 860 870 880 890 900
pF1KA0 ARLQWALQAYQGQLLQEGATRLLRFAASMKASRQQLQAQQQVQAAHSLHRAVRRCATLWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARLQWALQAYQGQLLQEGATRLLRFAASMKASRQQLQAQQQVQAAHSLHRAVRRCATLWK
820 830 840 850 860 870
910 920 930 940 950 960
pF1KA0 QKVLGRGGKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKVLGRGGKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLAA
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KA0 EEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAP
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KA0 TALVPHSPLPGALSSAPGPKQPPTASTGPELLLLPPSSFMPCGAAAPARVSAQRATPRDK
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
XP_016 TALVPHSPLPGALSSAPGPKQPPTASTGPELLLLPLSSFMPCGAAAPARVSAQRATPRDK
1000 1010 1020 1030 1040 1050
1090 1100 1110 1120 1130 1140
pF1KA0 PPVPSSLASVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAELEEIQQQLLHYQTTKQNLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPVPSSLASVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAELEEIQQQLLHYQTTKQNLW
1060 1070 1080 1090 1100 1110
1150 1160 1170
pF1KA0 SCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELEQV----------------------
::::::::::::::::::::::::::::::::::::::
XP_016 SCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELEQVRPQAIPRCPWGRPGLCSLSALP
1120 1130 1140 1150 1160 1170
1180 1190 1200 1210
pF1KA0 -------EMQIQLLAEELQAQRQPIGACVARIQALRQALC
:::::::::::::::::::::::::::::::::
XP_016 VPPWPQVEMQIQLLAEELQAQRQPIGACVARIQALRQALC
1180 1190 1200 1210
>>XP_016884644 (OMIM: 612765) PREDICTED: protein SFI1 ho (1158 aa)
initn: 7964 init1: 7392 opt: 7393 Z-score: 3785.2 bits: 712.4 E(85289): 4.3e-204
Smith-Waterman score: 7556; 90.9% identity (91.0% similar) in 1240 aa overlap (1-1211:1-1158)
10 20 30 40 50 60
pF1KA0 MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRR
:::::::::::::::::::::::::::::::
XP_016 MKNLLTEKCISSHNFHQKVIKQRMEKKVDSR-----------------------------
10 20 30
70 80 90 100 110 120
pF1KA0 ELPSTSHLVQYRGTHTCTRQGRLRELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRL
:::::::
XP_016 -----------------------------------------------------FYYEQRL
130 140 150 160 170 180
pF1KA0 LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV
40 50 60 70 80 90
190 200 210 220 230 240
pF1KA0 HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL
100 110 120 130 140 150
250 260 270 280 290 300
pF1KA0 HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR
160 170 180 190 200 210
310 320 330 340 350 360
pF1KA0 RVKRQQNEMAERFHHVTVLQIHFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK
:::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::
XP_016 RVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK
220 230 240 250 260 270
370 380 390 400 410 420
pF1KA0 HYMLLCAEEAAQFEMAEEHHRHSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HYMLLCAEEAAQFEMAEEHHRHSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIA
280 290 300 310 320 330
430 440 450 460 470 480
pF1KA0 LLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARAT
340 350 360 370 380 390
490 500 510 520 530 540
pF1KA0 RFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQE
400 410 420 430 440 450
550 560 570 580 590 600
pF1KA0 WQTVACAHHRHGRLKKAFCLWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQWRECLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WQTVACAHHRHGRLKKAFCLWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQWRECLAL
460 470 480 490 500 510
610 620 630 640 650 660
pF1KA0 RGAERQKLMRADLHHQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQLLRGALRRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGAERQKLMRADLHHQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQLLRGALRRW
520 530 540 550 560 570
670 680 690 700 710 720
pF1KA0 KENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMYYRQQEDCAIWEAQKVLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMYYRQQEDCAIWEAQKVLDR
580 590 600 610 620 630
730 740 750 760 770 780
pF1KA0 GCLRTWFQRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHHLQCVRKRLLHRQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCLRTWFQRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHHLQCVRKRLLHRQS
640 650 660 670 680 690
790 800 810 820 830 840
pF1KA0 TQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFSLQAKVWATWLAFVLERRRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFSLQAKVWATWLAFVLERRRKK
700 710 720 730 740 750
850 860 870 880 890 900
pF1KA0 ARLQWALQAYQGQLLQEGATRLLRFAASMKASRQQLQAQQQVQAAHSLHRAVRRCATLWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARLQWALQAYQGQLLQEGATRLLRFAASMKASRQQLQAQQQVQAAHSLHRAVRRCATLWK
760 770 780 790 800 810
910 920 930 940 950 960
pF1KA0 QKVLGRGGKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKVLGRGGKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLAA
820 830 840 850 860 870
970 980 990 1000 1010 1020
pF1KA0 EEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAP
880 890 900 910 920 930
1030 1040 1050 1060 1070 1080
pF1KA0 TALVPHSPLPGALSSAPGPKQPPTASTGPELLLLPPSSFMPCGAAAPARVSAQRATPRDK
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
XP_016 TALVPHSPLPGALSSAPGPKQPPTASTGPELLLLPLSSFMPCGAAAPARVSAQRATPRDK
940 950 960 970 980 990
1090 1100 1110 1120 1130 1140
pF1KA0 PPVPSSLASVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAELEEIQQQLLHYQTTKQNLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPVPSSLASVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAELEEIQQQLLHYQTTKQNLW
1000 1010 1020 1030 1040 1050
1150 1160 1170
pF1KA0 SCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELEQV----------------------
::::::::::::::::::::::::::::::::::::::
XP_016 SCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELEQVRPQAIPRCPWGRPGLCSLSALP
1060 1070 1080 1090 1100 1110
1180 1190 1200 1210
pF1KA0 -------EMQIQLLAEELQAQRQPIGACVARIQALRQALC
:::::::::::::::::::::::::::::::::
XP_016 VPPWPQVEMQIQLLAEELQAQRQPIGACVARIQALRQALC
1120 1130 1140 1150
1211 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 09:40:43 2016 done: Thu Nov 3 09:40:45 2016
Total Scan time: 15.580 Total Display time: 0.570
Function used was FASTA [36.3.4 Apr, 2011]