Result of FASTA (omim) for
pF1KA0411
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0411, 1075 aa
1>>>pF1KA0411 1075 - 1075 aa - 1075 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.4830+/-0.000464; mu= 9.6187+/- 0.029
mean_var=291.7092+/-63.770, 0's: 0 Z-trim(117.3): 391 B-trim: 1722 in 1/61
Lambda= 0.075093
statistics sampled from 28773 (29190) to 28773 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.674), E-opt: 0.2 (0.342), width: 16
Scan time: 11.440
The best scores are: opt bits E(85289)
NP_001028289 (OMIM: 606525) SLIT-ROBO Rho GTPase-a (1075) 7085 782.6 0
XP_016863064 (OMIM: 606525) PREDICTED: SLIT-ROBO R (1093) 6954 768.4 0
NP_001333130 (OMIM: 188470,606523) SLIT-ROBO Rho G (1062) 4812 536.4 3.3e-151
XP_016863069 (OMIM: 606525) PREDICTED: SLIT-ROBO R ( 709) 4689 522.8 2.7e-147
XP_011532603 (OMIM: 606525) PREDICTED: SLIT-ROBO R ( 941) 4004 448.8 7e-125
XP_011532598 (OMIM: 606525) PREDICTED: SLIT-ROBO R (1085) 4004 448.8 7.6e-125
XP_011532597 (OMIM: 606525) PREDICTED: SLIT-ROBO R (1104) 4004 448.9 7.7e-125
XP_011532605 (OMIM: 606525) PREDICTED: SLIT-ROBO R ( 591) 3944 442.0 4.7e-123
XP_016863067 (OMIM: 606525) PREDICTED: SLIT-ROBO R ( 979) 3938 441.6 1e-122
XP_016863065 (OMIM: 606525) PREDICTED: SLIT-ROBO R ( 979) 3938 441.6 1e-122
XP_016863066 (OMIM: 606525) PREDICTED: SLIT-ROBO R ( 979) 3938 441.6 1e-122
NP_055665 (OMIM: 606525) SLIT-ROBO Rho GTPase-acti (1099) 3938 441.7 1.1e-122
XP_016863063 (OMIM: 606525) PREDICTED: SLIT-ROBO R (1117) 3938 441.7 1.1e-122
NP_001164108 (OMIM: 606524) SLIT-ROBO Rho GTPase-a (1070) 3367 379.8 4.5e-104
XP_005277568 (OMIM: 606524) PREDICTED: SLIT-ROBO R (1070) 3367 379.8 4.5e-104
NP_056141 (OMIM: 606524) SLIT-ROBO Rho GTPase-acti (1071) 3355 378.5 1.1e-103
XP_005277567 (OMIM: 606524) PREDICTED: SLIT-ROBO R (1071) 3355 378.5 1.1e-103
XP_011507657 (OMIM: 606524) PREDICTED: SLIT-ROBO R (1083) 3202 362.0 1.1e-98
XP_011507656 (OMIM: 606524) PREDICTED: SLIT-ROBO R (1084) 3190 360.7 2.7e-98
XP_016856328 (OMIM: 606524) PREDICTED: SLIT-ROBO R ( 931) 3184 359.9 3.8e-98
XP_016856329 (OMIM: 606524) PREDICTED: SLIT-ROBO R ( 931) 3184 359.9 3.8e-98
XP_016856327 (OMIM: 606524) PREDICTED: SLIT-ROBO R ( 931) 3184 359.9 3.8e-98
XP_011507658 (OMIM: 606524) PREDICTED: SLIT-ROBO R ( 986) 2966 336.3 5.1e-91
XP_016863068 (OMIM: 606525) PREDICTED: SLIT-ROBO R ( 876) 2951 334.7 1.5e-90
XP_016856330 (OMIM: 606524) PREDICTED: SLIT-ROBO R ( 840) 2893 328.4 1.1e-88
XP_011507661 (OMIM: 606524) PREDICTED: SLIT-ROBO R ( 841) 2881 327.1 2.7e-88
NP_001287881 (OMIM: 606524) SLIT-ROBO Rho GTPase-a ( 789) 2848 323.4 3.1e-87
XP_005277572 (OMIM: 606524) PREDICTED: SLIT-ROBO R ( 789) 2848 323.4 3.1e-87
XP_005277571 (OMIM: 606524) PREDICTED: SLIT-ROBO R ( 790) 2836 322.1 7.7e-87
NP_065813 (OMIM: 188470,606523) SLIT-ROBO Rho GTPa (1085) 2427 278.0 2e-73
XP_011536883 (OMIM: 188470,606523) PREDICTED: SLIT (1045) 2222 255.8 9.7e-67
XP_011536882 (OMIM: 188470,606523) PREDICTED: SLIT (1045) 2222 255.8 9.7e-67
XP_016857581 (OMIM: 614703) PREDICTED: SLIT-ROBO R ( 305) 1212 145.7 3.8e-34
NP_001317613 (OMIM: 614703) SLIT-ROBO Rho GTPase-a ( 305) 1212 145.7 3.8e-34
XP_016857580 (OMIM: 614703) PREDICTED: SLIT-ROBO R ( 305) 1212 145.7 3.8e-34
XP_016857574 (OMIM: 614703) PREDICTED: SLIT-ROBO R ( 458) 1212 145.9 5e-34
NP_001258801 (OMIM: 614704) SLIT-ROBO Rho GTPase-a ( 458) 1205 145.2 8.4e-34
XP_016857578 (OMIM: 614703) PREDICTED: SLIT-ROBO R ( 306) 1200 144.4 9.5e-34
XP_016857577 (OMIM: 614703) PREDICTED: SLIT-ROBO R ( 306) 1200 144.4 9.5e-34
XP_005277479 (OMIM: 614703) PREDICTED: SLIT-ROBO R ( 306) 1200 144.4 9.5e-34
XP_005277478 (OMIM: 614703) PREDICTED: SLIT-ROBO R ( 306) 1200 144.4 9.5e-34
XP_016857575 (OMIM: 614703) PREDICTED: SLIT-ROBO R ( 428) 1200 144.6 1.2e-33
XP_011540317 (OMIM: 614704) PREDICTED: SLIT-ROBO R ( 428) 1184 142.9 3.9e-33
XP_016857638 (OMIM: 614704) PREDICTED: SLIT-ROBO R ( 306) 1177 141.9 5.3e-33
XP_005277556 (OMIM: 614704) PREDICTED: SLIT-ROBO R ( 306) 1177 141.9 5.3e-33
NP_001657 (OMIM: 300023) rho GTPase-activating pro ( 946) 1091 133.2 7e-30
NP_001158213 (OMIM: 300023) rho GTPase-activating ( 986) 1091 133.2 7.2e-30
XP_016857576 (OMIM: 614703) PREDICTED: SLIT-ROBO R ( 307) 945 116.8 2e-25
NP_001258799 (OMIM: 614703) SLIT-ROBO Rho GTPase-a ( 459) 945 117.0 2.5e-25
NP_001316913 (OMIM: 614704) SLIT-ROBO Rho GTPase-a ( 459) 936 116.0 5e-25
>>NP_001028289 (OMIM: 606525) SLIT-ROBO Rho GTPase-activ (1075 aa)
initn: 7085 init1: 7085 opt: 7085 Z-score: 4166.3 bits: 782.6 E(85289): 0
Smith-Waterman score: 7085; 100.0% identity (100.0% similar) in 1075 aa overlap (1-1075:1-1075)
10 20 30 40 50 60
pF1KA0 MSSQTKFKKDKEIIAEYEAQIKEIRTQLVEQFKCLEQQSESRLQLLQDLQEFFRRKAEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSQTKFKKDKEIIAEYEAQIKEIRTQLVEQFKCLEQQSESRLQLLQDLQEFFRRKAEIE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LEYSRSLEKLAERFSSKIRSSREHQFKKDQYLLSPVNCWYLVLHQTRRESRDHATLNDIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEYSRSLEKLAERFSSKIRSSREHQFKKDQYLLSPVNCWYLVLHQTRRESRDHATLNDIF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 MNNVIVRLSQISEDVIRLFKKSKEIGLQMHEELLKVTNELYTVMKTYHMYHAESISAESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNNVIVRLSQISEDVIRLFKKSKEIGLQMHEELLKVTNELYTVMKTYHMYHAESISAESK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKEAEKQEEKQFNKSGDLSMNLLRHEDRPQRRSSVKKIEKMKEKRQAKYSENKLKCTKAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKEAEKQEEKQFNKSGDLSMNLLRHEDRPQRRSSVKKIEKMKEKRQAKYSENKLKCTKAR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 NDYLLNLAATNAAISKYYIHDVSDLIDCCDLGFHASLARTFRTYLSAEYNLETSRHEGLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NDYLLNLAATNAAISKYYIHDVSDLIDCCDLGFHASLARTFRTYLSAEYNLETSRHEGLD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 VIENAVDNLDSRSDKHTVMDMCNQVFCPPLKFEFQPHMGDEVCQVSAQQPVQTELLMRYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIENAVDNLDSRSDKHTVMDMCNQVFCPPLKFEFQPHMGDEVCQVSAQQPVQTELLMRYH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 QLQSRLATLKIENEEVRKTLDATMQTLQDMLTVEDFDVSDAFQHSRSTESVKSAASETYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLQSRLATLKIENEEVRKTLDATMQTLQDMLTVEDFDVSDAFQHSRSTESVKSAASETYM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 SKINIAKRRANQQETEMFYFTKFKEYVNGSNLITKLQAKHDLLKQTLGEGERAECGTTRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKINIAKRRANQQETEMFYFTKFKEYVNGSNLITKLQAKHDLLKQTLGEGERAECGTTRG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 RRNARTRNQDSGQAIPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRNARTRNQDSGQAIPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 VDDQNERDINSVAGVLKLYFRGLENPLFPKERFQDLISTIKLENPAERVHQIQQILVTLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDDQNERDINSVAGVLKLYFRGLENPLFPKERFQDLISTIKLENPAERVHQIQQILVTLP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 RVVIVVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVSCQAHINEVIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVVIVVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVSCQAHINEVIK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 TIIIHHEAIFPSPRELEGPVYEKCMAGGEEYCDSPHSEPGAIDEVDHDNGTEPHTSDEEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIIIHHEAIFPSPRELEGPVYEKCMAGGEEYCDSPHSEPGAIDEVDHDNGTEPHTSDEEV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 EQIEAIAKFDYMGRSPRELSFKKGASLLLYHRASEDWWEGRHNGVDGLIPHQYIVVQDMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQIEAIAKFDYMGRSPRELSFKKGASLLLYHRASEDWWEGRHNGVDGLIPHQYIVVQDMD
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 DAFSDSLSQKADSEASSGPLLDDKASSKNDLQSPTEHISDYGFGGVMGRVRLRSDGAAIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DAFSDSLSQKADSEASSGPLLDDKASSKNDLQSPTEHISDYGFGGVMGRVRLRSDGAAIP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 RRRSGGDTHSPPRGLGPSIDTPPRAAACPSSPHKIPLTRGRIESPEKRRMATFGSAGSIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRRSGGDTHSPPRGLGPSIDTPPRAAACPSSPHKIPLTRGRIESPEKRRMATFGSAGSIN
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 YPDKKALSEGHSMRSTCGSTRHSSLGDHKSLEAEALAEDIEKTMSTALHELRELERQNTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPDKKALSEGHSMRSTCGSTRHSSLGDHKSLEAEALAEDIEKTMSTALHELRELERQNTV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 KQAPDVVLDTLEPLKNPPGPVSSEPASPLHTIVIRDPDAAMRRSSSSSTEMMTTFKPALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQAPDVVLDTLEPLKNPPGPVSSEPASPLHTIVIRDPDAAMRRSSSSSTEMMTTFKPALS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KA0 ARLAGAQLRPPPMRPVRPVVQHRSSSSSSSGVGSPAVTPTEKMFPNSSADKSGTM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARLAGAQLRPPPMRPVRPVVQHRSSSSSSSGVGSPAVTPTEKMFPNSSADKSGTM
1030 1040 1050 1060 1070
>>XP_016863064 (OMIM: 606525) PREDICTED: SLIT-ROBO Rho G (1093 aa)
initn: 6954 init1: 6954 opt: 6954 Z-score: 4089.5 bits: 768.4 E(85289): 0
Smith-Waterman score: 6954; 99.9% identity (100.0% similar) in 1054 aa overlap (22-1075:40-1093)
10 20 30 40 50
pF1KA0 MSSQTKFKKDKEIIAEYEAQIKEIRTQLVEQFKCLEQQSESRLQLLQDLQE
.:::::::::::::::::::::::::::::
XP_016 AGGAGGCLLMPCSTQDLQWELGSALGAAFRQEIRTQLVEQFKCLEQQSESRLQLLQDLQE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KA0 FFRRKAEIELEYSRSLEKLAERFSSKIRSSREHQFKKDQYLLSPVNCWYLVLHQTRRESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFRRKAEIELEYSRSLEKLAERFSSKIRSSREHQFKKDQYLLSPVNCWYLVLHQTRRESR
70 80 90 100 110 120
120 130 140 150 160 170
pF1KA0 DHATLNDIFMNNVIVRLSQISEDVIRLFKKSKEIGLQMHEELLKVTNELYTVMKTYHMYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DHATLNDIFMNNVIVRLSQISEDVIRLFKKSKEIGLQMHEELLKVTNELYTVMKTYHMYH
130 140 150 160 170 180
180 190 200 210 220 230
pF1KA0 AESISAESKLKEAEKQEEKQFNKSGDLSMNLLRHEDRPQRRSSVKKIEKMKEKRQAKYSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AESISAESKLKEAEKQEEKQFNKSGDLSMNLLRHEDRPQRRSSVKKIEKMKEKRQAKYSE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KA0 NKLKCTKARNDYLLNLAATNAAISKYYIHDVSDLIDCCDLGFHASLARTFRTYLSAEYNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKLKCTKARNDYLLNLAATNAAISKYYIHDVSDLIDCCDLGFHASLARTFRTYLSAEYNL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KA0 ETSRHEGLDVIENAVDNLDSRSDKHTVMDMCNQVFCPPLKFEFQPHMGDEVCQVSAQQPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETSRHEGLDVIENAVDNLDSRSDKHTVMDMCNQVFCPPLKFEFQPHMGDEVCQVSAQQPV
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA0 QTELLMRYHQLQSRLATLKIENEEVRKTLDATMQTLQDMLTVEDFDVSDAFQHSRSTESV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTELLMRYHQLQSRLATLKIENEEVRKTLDATMQTLQDMLTVEDFDVSDAFQHSRSTESV
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA0 KSAASETYMSKINIAKRRANQQETEMFYFTKFKEYVNGSNLITKLQAKHDLLKQTLGEGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSAASETYMSKINIAKRRANQQETEMFYFTKFKEYVNGSNLITKLQAKHDLLKQTLGEGE
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA0 RAECGTTRGRRNARTRNQDSGQAIPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAECGTTRGRRNARTRNQDSGQAIPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKN
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA0 SFERGEDPLVDDQNERDINSVAGVLKLYFRGLENPLFPKERFQDLISTIKLENPAERVHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFERGEDPLVDDQNERDINSVAGVLKLYFRGLENPLFPKERFQDLISTIKLENPAERVHQ
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA0 IQQILVTLPRVVIVVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQQILVTLPRVVIVVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVSC
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA0 QAHINEVIKTIIIHHEAIFPSPRELEGPVYEKCMAGGEEYCDSPHSEPGAIDEVDHDNGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAHINEVIKTIIIHHEAIFPSPRELEGPVYEKCMAGGEEYCDSPHSEPGAIDEVDHDNGT
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA0 EPHTSDEEVEQIEAIAKFDYMGRSPRELSFKKGASLLLYHRASEDWWEGRHNGVDGLIPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPHTSDEEVEQIEAIAKFDYMGRSPRELSFKKGASLLLYHRASEDWWEGRHNGVDGLIPH
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA0 QYIVVQDMDDAFSDSLSQKADSEASSGPLLDDKASSKNDLQSPTEHISDYGFGGVMGRVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYIVVQDMDDAFSDSLSQKADSEASSGPLLDDKASSKNDLQSPTEHISDYGFGGVMGRVR
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA0 LRSDGAAIPRRRSGGDTHSPPRGLGPSIDTPPRAAACPSSPHKIPLTRGRIESPEKRRMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRSDGAAIPRRRSGGDTHSPPRGLGPSIDTPPRAAACPSSPHKIPLTRGRIESPEKRRMA
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA0 TFGSAGSINYPDKKALSEGHSMRSTCGSTRHSSLGDHKSLEAEALAEDIEKTMSTALHEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFGSAGSINYPDKKALSEGHSMRSTCGSTRHSSLGDHKSLEAEALAEDIEKTMSTALHEL
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KA0 RELERQNTVKQAPDVVLDTLEPLKNPPGPVSSEPASPLHTIVIRDPDAAMRRSSSSSTEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RELERQNTVKQAPDVVLDTLEPLKNPPGPVSSEPASPLHTIVIRDPDAAMRRSSSSSTEM
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KA0 MTTFKPALSARLAGAQLRPPPMRPVRPVVQHRSSSSSSSGVGSPAVTPTEKMFPNSSADK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTTFKPALSARLAGAQLRPPPMRPVRPVVQHRSSSSSSSGVGSPAVTPTEKMFPNSSADK
1030 1040 1050 1060 1070 1080
pF1KA0 SGTM
::::
XP_016 SGTM
1090
>>NP_001333130 (OMIM: 188470,606523) SLIT-ROBO Rho GTPas (1062 aa)
initn: 3768 init1: 2247 opt: 4812 Z-score: 2835.5 bits: 536.4 E(85289): 3.3e-151
Smith-Waterman score: 4812; 68.9% identity (87.2% similar) in 1072 aa overlap (1-1062:1-1058)
10 20 30 40 50 60
pF1KA0 MSSQTKFKKDKEIIAEYEAQIKEIRTQLVEQFKCLEQQSESRLQLLQDLQEFFRRKAEIE
::. ..::::::::::::.:.::::.::::: ::::::.: :.:::::::.:::.:::::
NP_001 MSTPSRFKKDKEIIAEYESQVKEIRAQLVEQQKCLEQQTEMRVQLLQDLQDFFRKKAEIE
10 20 30 40 50 60
70 80 90 100 110
pF1KA0 LEYSRSLEKLAERFSSKIRSSREHQ-FKKDQYLLSPVNCWYLVLHQTRRESRDHATLNDI
::::.:::::::: .: ::...:: .:::: ::::::::::.:.:.::::.:::::.::
NP_001 TEYSRNLEKLAERFMAKTRSTKDHQQYKKDQNLLSPVNCWYLLLNQVRRESKDHATLSDI
70 80 90 100 110 120
120 130 140 150 160 170
pF1KA0 FMNNVIVRLSQISEDVIRLFKKSKEIGLQMHEELLKVTNELYTVMKTYHMYHAESISAES
..::::.:. ::::: :.:::::::..:.::.:.:: ::::::::::::::::::::::
NP_001 YLNNVIMRFMQISEDSTRMFKKSKEIAFQLHEDLMKVLNELYTVMKTYHMYHAESISAES
130 140 150 160 170 180
180 190 200 210 220 230
pF1KA0 KLKEAEKQEEKQFNKSGDLSMNLLRHEDRPQRRSSVKKIEKMKEKRQAKYSENKLKCTKA
::::::::::::...::: ... : :.: :::::::::::::::::::::::::: ::
NP_001 KLKEAEKQEEKQIGRSGDPVFHI-RLEERHQRRSSVKKIEKMKEKRQAKYSENKLKSIKA
190 200 210 220 230
240 250 260 270 280 290
pF1KA0 RNDYLLNLAATNAAISKYYIHDVSDLIDCCDLGFHASLARTFRTYLSAEYNLETSRHEGL
::.:::.: ::::.. ::::::.::::::::::.:::: :..::::::::::::::::::
NP_001 RNEYLLTLEATNASVFKYYIHDLSDLIDCCDLGYHASLNRALRTYLSAEYNLETSRHEGL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KA0 DVIENAVDNLDSRSDKHTVMDMCNQVFCPPLKFEFQPHMGDEVCQVSAQQPVQTELLMRY
:.::::::::. ::::. :.: .::::.::::: ::::::::::::::::.::..::
NP_001 DIIENAVDNLEPRSDKQRFMEMYPAAFCPPMKFEFQSHMGDEVCQVSAQQPVQAELMLRY
300 310 320 330 340 350
360 370 380 390 400 410
pF1KA0 HQLQSRLATLKIENEEVRKTLDATMQTLQDMLTVEDFDVSDAFQHSRSTESVKSAASETY
.::::::::::::::::.:: .::.::.:::.:.::.:::. ::::::::::::..::::
NP_001 QQLQSRLATLKIENEEVKKTTEATLQTIQDMVTIEDYDVSECFQHSRSTESVKSTVSETY
360 370 380 390 400 410
420 430 440 450 460 470
pF1KA0 MSKINIAKRRANQQETEMFYFTKFKEYVNGSNLITKLQAKHDLLKQTLGEGERAECGTT-
.:: .::::::::::::.::: :..::..:::::::::::::::..:::::.::: ::
NP_001 LSKPSIAKRRANQQETEQFYFMKLREYLEGSNLITKLQAKHDLLQRTLGEGHRAEYMTTS
420 430 440 450 460 470
480 490 500 510 520 530
pF1KA0 RGRRNARTRNQDSGQAIPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGED
:::::..::.:::::.:::.::::::.:::::::.:::::: :::::::::::::::::.
NP_001 RGRRNSHTRHQDSGQVIPLIVESCIRFINLYGLQHQGIFRVSGSQVEVNDIKNSFERGEN
480 490 500 510 520 530
540 550 560 570 580 590
pF1KA0 PLVDDQNERDINSVAGVLKLYFRGLENPLFPKERFQDLISTIKLENPAERVHQIQQILVT
::.:::...::::::::::::::::::::::::::.:::: :...: ::. .:...:.:
NP_001 PLADDQSNHDINSVAGVLKLYFRGLENPLFPKERFNDLISCIRIDNLYERALHIRKLLLT
540 550 560 570 580 590
600 610 620 630 640 650
pF1KA0 LPRVVIVVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVSCQAHINEV
::: :..::::::::::::::::::::::::::::::::::: .:. :: ::::::.::.
NP_001 LPRSVLIVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMPVPEIQDQVSCQAHVNEI
600 610 620 630 640 650
660 670 680 690 700 710
pF1KA0 IKTIIIHHEAIFPSPRELEGPVYEKCMAGGEEYCDSPHSEPGAIDEVDHDNGTEPHTSDE
:::::::::.:::. .::.:::::::::: ..:::::.:: :...:::.: :::::::..
NP_001 IKTIIIHHETIFPDAKELDGPVYEKCMAG-DDYCDSPYSEHGTLEEVDQDAGTEPHTSED
660 670 680 690 700 710
720 730 740 750 760 770
pF1KA0 EVEQIEAIAKFDYMGRSPRELSFKKGASLLLYHRASEDWWEGRHNGVDGLIPHQYIVVQD
: : :::::::::.::: ::::::::::::::::::::::::::::.:::.:::::::::
NP_001 ECEPIEAIAKFDYVGRSARELSFKKGASLLLYHRASEDWWEGRHNGIDGLVPHQYIVVQD
720 730 740 750 760 770
780 790 800 810 820 830
pF1KA0 MDDAFSDSLSQKADSEASSGPLLDDKASSKNDLQSPTEHISDYGFGGVMGRVRLRSDGAA
:::.:::.:::::::::::::. .::.::: :..:::.. : : ..: : :..
NP_001 MDDTFSDTLSQKADSEASSGPVTEDKSSSK-DMNSPTDRHPD----GYLARQRKRGEPPP
780 790 800 810 820 830
840 850 860 870 880 890
pF1KA0 IPRRRSG--GDTHSP---PRGLG-PSIDTPPRAAACPSSPHKIPLTRG-RIESPEKRRMA
: :: : .: : : :..:. :.: . : : :. . .:: .:::.::
NP_001 -PVRRPGRTSDGHCPLHPPHALSNSSVDLGSPSLA--SHPRGLLQNRGLNNDSPERRRRP
840 850 860 870 880 890
900 910 920 930 940 950
pF1KA0 TFGSAGSINYPDKKALSEGHSMRSTCGSTRHSSLGDHKSLEAEALAEDIEKTMSTALHEL
:: .:. :. .. .: . .: ......::: :. :..:.:::.::.:::.::
NP_001 GHGSLTNISRHDSLKKIDSPPIRRSTSSGQYTGFNDHKPLDPETIAQDIEETMNTALNEL
900 910 920 930 940 950
960 970 980 990 1000 1010
pF1KA0 RELERQNTVKQAPDVVLDTLEPLKNPPGPVSS-EPASPLHTIVIRDPDAAMRRSSSSSTE
::::::.:.:.:::::::::: .:: : :..: : ::::....:. . .:::.:::..
NP_001 RELERQSTAKHAPDVVLDTLEQVKNSPTPATSTESLSPLHNVALRSSEPQIRRSTSSSSD
960 970 980 990 1000 1010
1020 1030 1040 1050 1060 1070
pF1KA0 MMTTFKPALSARLAGAQLRPPPMRPVRPVVQHRSSSSSSSGVGSPAVTPTEKMFPNSSAD
:.:::: .. :. :.::.:: .:: .:.: ... . : . : ::.:
NP_001 TMSTFKPMVAPRM-GVQLKPPALRP-KPAVLPKTNPT--IGPAPPPQGPTDKSCTM
1020 1030 1040 1050 1060
pF1KA0 KSGTM
>>XP_016863069 (OMIM: 606525) PREDICTED: SLIT-ROBO Rho G (709 aa)
initn: 4689 init1: 4689 opt: 4689 Z-score: 2765.5 bits: 522.8 E(85289): 2.7e-147
Smith-Waterman score: 4689; 100.0% identity (100.0% similar) in 709 aa overlap (121-829:1-709)
100 110 120 130 140 150
pF1KA0 YLLSPVNCWYLVLHQTRRESRDHATLNDIFMNNVIVRLSQISEDVIRLFKKSKEIGLQMH
::::::::::::::::::::::::::::::
XP_016 MNNVIVRLSQISEDVIRLFKKSKEIGLQMH
10 20 30
160 170 180 190 200 210
pF1KA0 EELLKVTNELYTVMKTYHMYHAESISAESKLKEAEKQEEKQFNKSGDLSMNLLRHEDRPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EELLKVTNELYTVMKTYHMYHAESISAESKLKEAEKQEEKQFNKSGDLSMNLLRHEDRPQ
40 50 60 70 80 90
220 230 240 250 260 270
pF1KA0 RRSSVKKIEKMKEKRQAKYSENKLKCTKARNDYLLNLAATNAAISKYYIHDVSDLIDCCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRSSVKKIEKMKEKRQAKYSENKLKCTKARNDYLLNLAATNAAISKYYIHDVSDLIDCCD
100 110 120 130 140 150
280 290 300 310 320 330
pF1KA0 LGFHASLARTFRTYLSAEYNLETSRHEGLDVIENAVDNLDSRSDKHTVMDMCNQVFCPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGFHASLARTFRTYLSAEYNLETSRHEGLDVIENAVDNLDSRSDKHTVMDMCNQVFCPPL
160 170 180 190 200 210
340 350 360 370 380 390
pF1KA0 KFEFQPHMGDEVCQVSAQQPVQTELLMRYHQLQSRLATLKIENEEVRKTLDATMQTLQDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFEFQPHMGDEVCQVSAQQPVQTELLMRYHQLQSRLATLKIENEEVRKTLDATMQTLQDM
220 230 240 250 260 270
400 410 420 430 440 450
pF1KA0 LTVEDFDVSDAFQHSRSTESVKSAASETYMSKINIAKRRANQQETEMFYFTKFKEYVNGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTVEDFDVSDAFQHSRSTESVKSAASETYMSKINIAKRRANQQETEMFYFTKFKEYVNGS
280 290 300 310 320 330
460 470 480 490 500 510
pF1KA0 NLITKLQAKHDLLKQTLGEGERAECGTTRGRRNARTRNQDSGQAIPLVVESCIRYINLYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLITKLQAKHDLLKQTLGEGERAECGTTRGRRNARTRNQDSGQAIPLVVESCIRYINLYG
340 350 360 370 380 390
520 530 540 550 560 570
pF1KA0 LQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAGVLKLYFRGLENPLFPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAGVLKLYFRGLENPLFPK
400 410 420 430 440 450
580 590 600 610 620 630
pF1KA0 ERFQDLISTIKLENPAERVHQIQQILVTLPRVVIVVMRYLFAFLNHLSQYSDENMMDPYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERFQDLISTIKLENPAERVHQIQQILVTLPRVVIVVMRYLFAFLNHLSQYSDENMMDPYN
460 470 480 490 500 510
640 650 660 670 680 690
pF1KA0 LAICFGPTLMHIPDGQDPVSCQAHINEVIKTIIIHHEAIFPSPRELEGPVYEKCMAGGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAICFGPTLMHIPDGQDPVSCQAHINEVIKTIIIHHEAIFPSPRELEGPVYEKCMAGGEE
520 530 540 550 560 570
700 710 720 730 740 750
pF1KA0 YCDSPHSEPGAIDEVDHDNGTEPHTSDEEVEQIEAIAKFDYMGRSPRELSFKKGASLLLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YCDSPHSEPGAIDEVDHDNGTEPHTSDEEVEQIEAIAKFDYMGRSPRELSFKKGASLLLY
580 590 600 610 620 630
760 770 780 790 800 810
pF1KA0 HRASEDWWEGRHNGVDGLIPHQYIVVQDMDDAFSDSLSQKADSEASSGPLLDDKASSKND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HRASEDWWEGRHNGVDGLIPHQYIVVQDMDDAFSDSLSQKADSEASSGPLLDDKASSKND
640 650 660 670 680 690
820 830 840 850 860 870
pF1KA0 LQSPTEHISDYGFGGVMGRVRLRSDGAAIPRRRSGGDTHSPPRGLGPSIDTPPRAAACPS
:::::::::::::::::::
XP_016 LQSPTEHISDYGFGGVMGR
700
>>XP_011532603 (OMIM: 606525) PREDICTED: SLIT-ROBO Rho G (941 aa)
initn: 4004 init1: 4004 opt: 4004 Z-score: 2363.1 bits: 448.8 E(85289): 7e-125
Smith-Waterman score: 5980; 96.8% identity (96.9% similar) in 941 aa overlap (164-1075:1-941)
140 150 160 170 180 190
pF1KA0 DVIRLFKKSKEIGLQMHEELLKVTNELYTVMKTYHMYHAESISAESKLKEAEKQEEKQFN
::::::::::::::::::::::::::::::
XP_011 MKTYHMYHAESISAESKLKEAEKQEEKQFN
10 20 30
200 210 220 230 240 250
pF1KA0 KSGDLSMNLLRHEDRPQRRSSVKKIEKMKEKRQAKYSENKLKCTKARNDYLLNLAATNAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSGDLSMNLLRHEDRPQRRSSVKKIEKMKEKRQAKYSENKLKCTKARNDYLLNLAATNAA
40 50 60 70 80 90
260 270 280 290 300 310
pF1KA0 ISKYYIHDVSDLIDCCDLGFHASLARTFRTYLSAEYNLETSRHEGLDVIENAVDNLDSRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISKYYIHDVSDLIDCCDLGFHASLARTFRTYLSAEYNLETSRHEGLDVIENAVDNLDSRS
100 110 120 130 140 150
320 330 340 350 360 370
pF1KA0 DKHTVMDMCNQVFCPPLKFEFQPHMGDEVCQVSAQQPVQTELLMRYHQLQSRLATLKIEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKHTVMDMCNQVFCPPLKFEFQPHMGDEVCQVSAQQPVQTELLMRYHQLQSRLATLKIEN
160 170 180 190 200 210
380 390 400 410 420 430
pF1KA0 EEVRKTLDATMQTLQDMLTVEDFDVSDAFQHSRSTESVKSAASETYMSKINIAKRRANQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEVRKTLDATMQTLQDMLTVEDFDVSDAFQHSRSTESVKSAASETYMSKINIAKRRANQQ
220 230 240 250 260 270
440 450 460 470
pF1KA0 ETEMFYFTKFKEYVNGSNLITKLQAKHDLLKQTLGEGERAECGTT---------------
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETEMFYFTKFKEYVNGSNLITKLQAKHDLLKQTLGEGERAECGTTSRRDGRLRLPHFPWP
280 290 300 310 320 330
480 490 500 510 520
pF1KA0 --------------RGRRNARTRNQDSGQAIPLVVESCIRYINLYGLQQQGIFRVPGSQV
.:::::::::::::::::::::::::::::::::::::::::::::
XP_011 SCPPAPHFVPHPALQGRRNARTRNQDSGQAIPLVVESCIRYINLYGLQQQGIFRVPGSQV
340 350 360 370 380 390
530 540 550 560 570 580
pF1KA0 EVNDIKNSFERGEDPLVDDQNERDINSVAGVLKLYFRGLENPLFPKERFQDLISTIKLEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVNDIKNSFERGEDPLVDDQNERDINSVAGVLKLYFRGLENPLFPKERFQDLISTIKLEN
400 410 420 430 440 450
590 600 610 620 630 640
pF1KA0 PAERVHQIQQILVTLPRVVIVVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMHIPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAERVHQIQQILVTLPRVVIVVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMHIPD
460 470 480 490 500 510
650 660 670 680 690 700
pF1KA0 GQDPVSCQAHINEVIKTIIIHHEAIFPSPRELEGPVYEKCMAGGEEYCDSPHSEPGAIDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQDPVSCQAHINEVIKTIIIHHEAIFPSPRELEGPVYEKCMAGGEEYCDSPHSEPGAIDE
520 530 540 550 560 570
710 720 730 740 750 760
pF1KA0 VDHDNGTEPHTSDEEVEQIEAIAKFDYMGRSPRELSFKKGASLLLYHRASEDWWEGRHNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDHDNGTEPHTSDEEVEQIEAIAKFDYMGRSPRELSFKKGASLLLYHRASEDWWEGRHNG
580 590 600 610 620 630
770 780 790 800 810 820
pF1KA0 VDGLIPHQYIVVQDMDDAFSDSLSQKADSEASSGPLLDDKASSKNDLQSPTEHISDYGFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDGLIPHQYIVVQDMDDAFSDSLSQKADSEASSGPLLDDKASSKNDLQSPTEHISDYGFG
640 650 660 670 680 690
830 840 850 860 870 880
pF1KA0 GVMGRVRLRSDGAAIPRRRSGGDTHSPPRGLGPSIDTPPRAAACPSSPHKIPLTRGRIES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVMGRVRLRSDGAAIPRRRSGGDTHSPPRGLGPSIDTPPRAAACPSSPHKIPLTRGRIES
700 710 720 730 740 750
890 900 910 920 930 940
pF1KA0 PEKRRMATFGSAGSINYPDKKALSEGHSMRSTCGSTRHSSLGDHKSLEAEALAEDIEKTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEKRRMATFGSAGSINYPDKKALSEGHSMRSTCGSTRHSSLGDHKSLEAEALAEDIEKTM
760 770 780 790 800 810
950 960 970 980 990 1000
pF1KA0 STALHELRELERQNTVKQAPDVVLDTLEPLKNPPGPVSSEPASPLHTIVIRDPDAAMRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STALHELRELERQNTVKQAPDVVLDTLEPLKNPPGPVSSEPASPLHTIVIRDPDAAMRRS
820 830 840 850 860 870
1010 1020 1030 1040 1050 1060
pF1KA0 SSSSTEMMTTFKPALSARLAGAQLRPPPMRPVRPVVQHRSSSSSSSGVGSPAVTPTEKMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSSSTEMMTTFKPALSARLAGAQLRPPPMRPVRPVVQHRSSSSSSSGVGSPAVTPTEKMF
880 890 900 910 920 930
1070
pF1KA0 PNSSADKSGTM
:::::::::::
XP_011 PNSSADKSGTM
940
>>XP_011532598 (OMIM: 606525) PREDICTED: SLIT-ROBO Rho G (1085 aa)
initn: 4004 init1: 4004 opt: 4004 Z-score: 2362.3 bits: 448.8 E(85289): 7.6e-125
Smith-Waterman score: 6884; 97.2% identity (97.3% similar) in 1083 aa overlap (22-1075:3-1085)
10 20 30 40 50 60
pF1KA0 MSSQTKFKKDKEIIAEYEAQIKEIRTQLVEQFKCLEQQSESRLQLLQDLQEFFRRKAEIE
:::::::::::::::::::::::::::::::::::::::
XP_011 MCKEIRTQLVEQFKCLEQQSESRLQLLQDLQEFFRRKAEIE
10 20 30 40
70 80 90 100 110 120
pF1KA0 LEYSRSLEKLAERFSSKIRSSREHQFKKDQYLLSPVNCWYLVLHQTRRESRDHATLNDIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEYSRSLEKLAERFSSKIRSSREHQFKKDQYLLSPVNCWYLVLHQTRRESRDHATLNDIF
50 60 70 80 90 100
130 140 150 160 170 180
pF1KA0 MNNVIVRLSQISEDVIRLFKKSKEIGLQMHEELLKVTNELYTVMKTYHMYHAESISAESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNNVIVRLSQISEDVIRLFKKSKEIGLQMHEELLKVTNELYTVMKTYHMYHAESISAESK
110 120 130 140 150 160
190 200 210 220 230 240
pF1KA0 LKEAEKQEEKQFNKSGDLSMNLLRHEDRPQRRSSVKKIEKMKEKRQAKYSENKLKCTKAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKEAEKQEEKQFNKSGDLSMNLLRHEDRPQRRSSVKKIEKMKEKRQAKYSENKLKCTKAR
170 180 190 200 210 220
250 260 270 280 290 300
pF1KA0 NDYLLNLAATNAAISKYYIHDVSDLIDCCDLGFHASLARTFRTYLSAEYNLETSRHEGLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NDYLLNLAATNAAISKYYIHDVSDLIDCCDLGFHASLARTFRTYLSAEYNLETSRHEGLD
230 240 250 260 270 280
310 320 330 340 350 360
pF1KA0 VIENAVDNLDSRSDKHTVMDMCNQVFCPPLKFEFQPHMGDEVCQVSAQQPVQTELLMRYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIENAVDNLDSRSDKHTVMDMCNQVFCPPLKFEFQPHMGDEVCQVSAQQPVQTELLMRYH
290 300 310 320 330 340
370 380 390 400 410 420
pF1KA0 QLQSRLATLKIENEEVRKTLDATMQTLQDMLTVEDFDVSDAFQHSRSTESVKSAASETYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLQSRLATLKIENEEVRKTLDATMQTLQDMLTVEDFDVSDAFQHSRSTESVKSAASETYM
350 360 370 380 390 400
430 440 450 460 470
pF1KA0 SKINIAKRRANQQETEMFYFTKFKEYVNGSNLITKLQAKHDLLKQTLGEGERAECGTT--
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKINIAKRRANQQETEMFYFTKFKEYVNGSNLITKLQAKHDLLKQTLGEGERAECGTTSR
410 420 430 440 450 460
480 490 500 510
pF1KA0 ---------------------------RGRRNARTRNQDSGQAIPLVVESCIRYINLYGL
.::::::::::::::::::::::::::::::::
XP_011 RDGRLRLPHFPWPSCPPAPHFVPHPALQGRRNARTRNQDSGQAIPLVVESCIRYINLYGL
470 480 490 500 510 520
520 530 540 550 560 570
pF1KA0 QQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAGVLKLYFRGLENPLFPKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAGVLKLYFRGLENPLFPKE
530 540 550 560 570 580
580 590 600 610 620 630
pF1KA0 RFQDLISTIKLENPAERVHQIQQILVTLPRVVIVVMRYLFAFLNHLSQYSDENMMDPYNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFQDLISTIKLENPAERVHQIQQILVTLPRVVIVVMRYLFAFLNHLSQYSDENMMDPYNL
590 600 610 620 630 640
640 650 660 670 680 690
pF1KA0 AICFGPTLMHIPDGQDPVSCQAHINEVIKTIIIHHEAIFPSPRELEGPVYEKCMAGGEEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AICFGPTLMHIPDGQDPVSCQAHINEVIKTIIIHHEAIFPSPRELEGPVYEKCMAGGEEY
650 660 670 680 690 700
700 710 720 730 740 750
pF1KA0 CDSPHSEPGAIDEVDHDNGTEPHTSDEEVEQIEAIAKFDYMGRSPRELSFKKGASLLLYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CDSPHSEPGAIDEVDHDNGTEPHTSDEEVEQIEAIAKFDYMGRSPRELSFKKGASLLLYH
710 720 730 740 750 760
760 770 780 790 800 810
pF1KA0 RASEDWWEGRHNGVDGLIPHQYIVVQDMDDAFSDSLSQKADSEASSGPLLDDKASSKNDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RASEDWWEGRHNGVDGLIPHQYIVVQDMDDAFSDSLSQKADSEASSGPLLDDKASSKNDL
770 780 790 800 810 820
820 830 840 850 860 870
pF1KA0 QSPTEHISDYGFGGVMGRVRLRSDGAAIPRRRSGGDTHSPPRGLGPSIDTPPRAAACPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSPTEHISDYGFGGVMGRVRLRSDGAAIPRRRSGGDTHSPPRGLGPSIDTPPRAAACPSS
830 840 850 860 870 880
880 890 900 910 920 930
pF1KA0 PHKIPLTRGRIESPEKRRMATFGSAGSINYPDKKALSEGHSMRSTCGSTRHSSLGDHKSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHKIPLTRGRIESPEKRRMATFGSAGSINYPDKKALSEGHSMRSTCGSTRHSSLGDHKSL
890 900 910 920 930 940
940 950 960 970 980 990
pF1KA0 EAEALAEDIEKTMSTALHELRELERQNTVKQAPDVVLDTLEPLKNPPGPVSSEPASPLHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAEALAEDIEKTMSTALHELRELERQNTVKQAPDVVLDTLEPLKNPPGPVSSEPASPLHT
950 960 970 980 990 1000
1000 1010 1020 1030 1040 1050
pF1KA0 IVIRDPDAAMRRSSSSSTEMMTTFKPALSARLAGAQLRPPPMRPVRPVVQHRSSSSSSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVIRDPDAAMRRSSSSSTEMMTTFKPALSARLAGAQLRPPPMRPVRPVVQHRSSSSSSSG
1010 1020 1030 1040 1050 1060
1060 1070
pF1KA0 VGSPAVTPTEKMFPNSSADKSGTM
::::::::::::::::::::::::
XP_011 VGSPAVTPTEKMFPNSSADKSGTM
1070 1080
>>XP_011532597 (OMIM: 606525) PREDICTED: SLIT-ROBO Rho G (1104 aa)
initn: 4004 init1: 4004 opt: 4004 Z-score: 2362.3 bits: 448.9 E(85289): 7.7e-125
Smith-Waterman score: 7011; 97.3% identity (97.4% similar) in 1104 aa overlap (1-1075:1-1104)
10 20 30 40 50 60
pF1KA0 MSSQTKFKKDKEIIAEYEAQIKEIRTQLVEQFKCLEQQSESRLQLLQDLQEFFRRKAEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSSQTKFKKDKEIIAEYEAQIKEIRTQLVEQFKCLEQQSESRLQLLQDLQEFFRRKAEIE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LEYSRSLEKLAERFSSKIRSSREHQFKKDQYLLSPVNCWYLVLHQTRRESRDHATLNDIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEYSRSLEKLAERFSSKIRSSREHQFKKDQYLLSPVNCWYLVLHQTRRESRDHATLNDIF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 MNNVIVRLSQISEDVIRLFKKSKEIGLQMHEELLKVTNELYTVMKTYHMYHAESISAESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNNVIVRLSQISEDVIRLFKKSKEIGLQMHEELLKVTNELYTVMKTYHMYHAESISAESK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKEAEKQEEKQFNKSGDLSMNLLRHEDRPQRRSSVKKIEKMKEKRQAKYSENKLKCTKAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKEAEKQEEKQFNKSGDLSMNLLRHEDRPQRRSSVKKIEKMKEKRQAKYSENKLKCTKAR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 NDYLLNLAATNAAISKYYIHDVSDLIDCCDLGFHASLARTFRTYLSAEYNLETSRHEGLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NDYLLNLAATNAAISKYYIHDVSDLIDCCDLGFHASLARTFRTYLSAEYNLETSRHEGLD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 VIENAVDNLDSRSDKHTVMDMCNQVFCPPLKFEFQPHMGDEVCQVSAQQPVQTELLMRYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIENAVDNLDSRSDKHTVMDMCNQVFCPPLKFEFQPHMGDEVCQVSAQQPVQTELLMRYH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 QLQSRLATLKIENEEVRKTLDATMQTLQDMLTVEDFDVSDAFQHSRSTESVKSAASETYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLQSRLATLKIENEEVRKTLDATMQTLQDMLTVEDFDVSDAFQHSRSTESVKSAASETYM
370 380 390 400 410 420
430 440 450 460 470
pF1KA0 SKINIAKRRANQQETEMFYFTKFKEYVNGSNLITKLQAKHDLLKQTLGEGERAECGTT--
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKINIAKRRANQQETEMFYFTKFKEYVNGSNLITKLQAKHDLLKQTLGEGERAECGTTSR
430 440 450 460 470 480
480 490 500 510
pF1KA0 ---------------------------RGRRNARTRNQDSGQAIPLVVESCIRYINLYGL
.::::::::::::::::::::::::::::::::
XP_011 RDGRLRLPHFPWPSCPPAPHFVPHPALQGRRNARTRNQDSGQAIPLVVESCIRYINLYGL
490 500 510 520 530 540
520 530 540 550 560 570
pF1KA0 QQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAGVLKLYFRGLENPLFPKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAGVLKLYFRGLENPLFPKE
550 560 570 580 590 600
580 590 600 610 620 630
pF1KA0 RFQDLISTIKLENPAERVHQIQQILVTLPRVVIVVMRYLFAFLNHLSQYSDENMMDPYNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFQDLISTIKLENPAERVHQIQQILVTLPRVVIVVMRYLFAFLNHLSQYSDENMMDPYNL
610 620 630 640 650 660
640 650 660 670 680 690
pF1KA0 AICFGPTLMHIPDGQDPVSCQAHINEVIKTIIIHHEAIFPSPRELEGPVYEKCMAGGEEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AICFGPTLMHIPDGQDPVSCQAHINEVIKTIIIHHEAIFPSPRELEGPVYEKCMAGGEEY
670 680 690 700 710 720
700 710 720 730 740 750
pF1KA0 CDSPHSEPGAIDEVDHDNGTEPHTSDEEVEQIEAIAKFDYMGRSPRELSFKKGASLLLYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CDSPHSEPGAIDEVDHDNGTEPHTSDEEVEQIEAIAKFDYMGRSPRELSFKKGASLLLYH
730 740 750 760 770 780
760 770 780 790 800 810
pF1KA0 RASEDWWEGRHNGVDGLIPHQYIVVQDMDDAFSDSLSQKADSEASSGPLLDDKASSKNDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RASEDWWEGRHNGVDGLIPHQYIVVQDMDDAFSDSLSQKADSEASSGPLLDDKASSKNDL
790 800 810 820 830 840
820 830 840 850 860 870
pF1KA0 QSPTEHISDYGFGGVMGRVRLRSDGAAIPRRRSGGDTHSPPRGLGPSIDTPPRAAACPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSPTEHISDYGFGGVMGRVRLRSDGAAIPRRRSGGDTHSPPRGLGPSIDTPPRAAACPSS
850 860 870 880 890 900
880 890 900 910 920 930
pF1KA0 PHKIPLTRGRIESPEKRRMATFGSAGSINYPDKKALSEGHSMRSTCGSTRHSSLGDHKSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHKIPLTRGRIESPEKRRMATFGSAGSINYPDKKALSEGHSMRSTCGSTRHSSLGDHKSL
910 920 930 940 950 960
940 950 960 970 980 990
pF1KA0 EAEALAEDIEKTMSTALHELRELERQNTVKQAPDVVLDTLEPLKNPPGPVSSEPASPLHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAEALAEDIEKTMSTALHELRELERQNTVKQAPDVVLDTLEPLKNPPGPVSSEPASPLHT
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KA0 IVIRDPDAAMRRSSSSSTEMMTTFKPALSARLAGAQLRPPPMRPVRPVVQHRSSSSSSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVIRDPDAAMRRSSSSSTEMMTTFKPALSARLAGAQLRPPPMRPVRPVVQHRSSSSSSSG
1030 1040 1050 1060 1070 1080
1060 1070
pF1KA0 VGSPAVTPTEKMFPNSSADKSGTM
::::::::::::::::::::::::
XP_011 VGSPAVTPTEKMFPNSSADKSGTM
1090 1100
>>XP_011532605 (OMIM: 606525) PREDICTED: SLIT-ROBO Rho G (591 aa)
initn: 3944 init1: 3944 opt: 3944 Z-score: 2330.2 bits: 442.0 E(85289): 4.7e-123
Smith-Waterman score: 3944; 99.8% identity (100.0% similar) in 588 aa overlap (488-1075:4-591)
460 470 480 490 500 510
pF1KA0 AKHDLLKQTLGEGERAECGTTRGRRNARTRNQDSGQAIPLVVESCIRYINLYGLQQQGIF
.:::::::::::::::::::::::::::::
XP_011 MRHHQDSGQAIPLVVESCIRYINLYGLQQQGIF
10 20 30
520 530 540 550 560 570
pF1KA0 RVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAGVLKLYFRGLENPLFPKERFQDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAGVLKLYFRGLENPLFPKERFQDLI
40 50 60 70 80 90
580 590 600 610 620 630
pF1KA0 STIKLENPAERVHQIQQILVTLPRVVIVVMRYLFAFLNHLSQYSDENMMDPYNLAICFGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STIKLENPAERVHQIQQILVTLPRVVIVVMRYLFAFLNHLSQYSDENMMDPYNLAICFGP
100 110 120 130 140 150
640 650 660 670 680 690
pF1KA0 TLMHIPDGQDPVSCQAHINEVIKTIIIHHEAIFPSPRELEGPVYEKCMAGGEEYCDSPHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLMHIPDGQDPVSCQAHINEVIKTIIIHHEAIFPSPRELEGPVYEKCMAGGEEYCDSPHS
160 170 180 190 200 210
700 710 720 730 740 750
pF1KA0 EPGAIDEVDHDNGTEPHTSDEEVEQIEAIAKFDYMGRSPRELSFKKGASLLLYHRASEDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPGAIDEVDHDNGTEPHTSDEEVEQIEAIAKFDYMGRSPRELSFKKGASLLLYHRASEDW
220 230 240 250 260 270
760 770 780 790 800 810
pF1KA0 WEGRHNGVDGLIPHQYIVVQDMDDAFSDSLSQKADSEASSGPLLDDKASSKNDLQSPTEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WEGRHNGVDGLIPHQYIVVQDMDDAFSDSLSQKADSEASSGPLLDDKASSKNDLQSPTEH
280 290 300 310 320 330
820 830 840 850 860 870
pF1KA0 ISDYGFGGVMGRVRLRSDGAAIPRRRSGGDTHSPPRGLGPSIDTPPRAAACPSSPHKIPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISDYGFGGVMGRVRLRSDGAAIPRRRSGGDTHSPPRGLGPSIDTPPRAAACPSSPHKIPL
340 350 360 370 380 390
880 890 900 910 920 930
pF1KA0 TRGRIESPEKRRMATFGSAGSINYPDKKALSEGHSMRSTCGSTRHSSLGDHKSLEAEALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRGRIESPEKRRMATFGSAGSINYPDKKALSEGHSMRSTCGSTRHSSLGDHKSLEAEALA
400 410 420 430 440 450
940 950 960 970 980 990
pF1KA0 EDIEKTMSTALHELRELERQNTVKQAPDVVLDTLEPLKNPPGPVSSEPASPLHTIVIRDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDIEKTMSTALHELRELERQNTVKQAPDVVLDTLEPLKNPPGPVSSEPASPLHTIVIRDP
460 470 480 490 500 510
1000 1010 1020 1030 1040 1050
pF1KA0 DAAMRRSSSSSTEMMTTFKPALSARLAGAQLRPPPMRPVRPVVQHRSSSSSSSGVGSPAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAAMRRSSSSSTEMMTTFKPALSARLAGAQLRPPPMRPVRPVVQHRSSSSSSSGVGSPAV
520 530 540 550 560 570
1060 1070
pF1KA0 TPTEKMFPNSSADKSGTM
::::::::::::::::::
XP_011 TPTEKMFPNSSADKSGTM
580 590
>>XP_016863067 (OMIM: 606525) PREDICTED: SLIT-ROBO Rho G (979 aa)
initn: 6234 init1: 3938 opt: 3938 Z-score: 2324.2 bits: 441.6 E(85289): 1e-122
Smith-Waterman score: 6189; 96.7% identity (97.0% similar) in 979 aa overlap (121-1075:1-979)
100 110 120 130 140 150
pF1KA0 YLLSPVNCWYLVLHQTRRESRDHATLNDIFMNNVIVRLSQISEDVIRLFKKSKEIGLQMH
::::::::::::::::::::::::::::::
XP_016 MNNVIVRLSQISEDVIRLFKKSKEIGLQMH
10 20 30
160 170 180 190 200 210
pF1KA0 EELLKVTNELYTVMKTYHMYHAESISAESKLKEAEKQEEKQFNKSGDLSMNLLRHEDRPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EELLKVTNELYTVMKTYHMYHAESISAESKLKEAEKQEEKQFNKSGDLSMNLLRHEDRPQ
40 50 60 70 80 90
220 230 240 250 260 270
pF1KA0 RRSSVKKIEKMKEKRQAKYSENKLKCTKARNDYLLNLAATNAAISKYYIHDVSDLIDCCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRSSVKKIEKMKEKRQAKYSENKLKCTKARNDYLLNLAATNAAISKYYIHDVSDLIDCCD
100 110 120 130 140 150
280 290 300 310 320 330
pF1KA0 LGFHASLARTFRTYLSAEYNLETSRHEGLDVIENAVDNLDSRSDKHTVMDMCNQVFCPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGFHASLARTFRTYLSAEYNLETSRHEGLDVIENAVDNLDSRSDKHTVMDMCNQVFCPPL
160 170 180 190 200 210
340 350 360 370 380 390
pF1KA0 KFEFQPHMGDEVCQVSAQQPVQTELLMRYHQLQSRLATLKIENEEVRKTLDATMQTLQDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFEFQPHMGDEVCQVSAQQPVQTELLMRYHQLQSRLATLKIENEEVRKTLDATMQTLQDM
220 230 240 250 260 270
400 410 420 430 440 450
pF1KA0 LTVEDFDVSDAFQHSRSTESVKSAASETYMSKINIAKRRANQQETEMFYFTKFKEYVNGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTVEDFDVSDAFQHSRSTESVKSAASETYMSKINIAKRRANQQETEMFYFTKFKEYVNGS
280 290 300 310 320 330
460 470 480
pF1KA0 NLITKLQAKHDLLKQTLGEGERAECGTTRG-------RRNARTRN---------------
::::::::::::::::::::::::::::: .. : :
XP_016 NLITKLQAKHDLLKQTLGEGERAECGTTRPPCLPPKPQKMRRPRPLSVYSHKLFNGSMEA
340 350 360 370 380 390
490 500 510 520 530 540
pF1KA0 --QDSGQAIPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNE
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIKDSGQAIPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNE
400 410 420 430 440 450
550 560 570 580 590 600
pF1KA0 RDINSVAGVLKLYFRGLENPLFPKERFQDLISTIKLENPAERVHQIQQILVTLPRVVIVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDINSVAGVLKLYFRGLENPLFPKERFQDLISTIKLENPAERVHQIQQILVTLPRVVIVV
460 470 480 490 500 510
610 620 630 640 650 660
pF1KA0 MRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVSCQAHINEVIKTIIIHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVSCQAHINEVIKTIIIHH
520 530 540 550 560 570
670 680 690 700 710 720
pF1KA0 EAIFPSPRELEGPVYEKCMAGGEEYCDSPHSEPGAIDEVDHDNGTEPHTSDEEVEQIEAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAIFPSPRELEGPVYEKCMAGGEEYCDSPHSEPGAIDEVDHDNGTEPHTSDEEVEQIEAI
580 590 600 610 620 630
730 740 750 760 770 780
pF1KA0 AKFDYMGRSPRELSFKKGASLLLYHRASEDWWEGRHNGVDGLIPHQYIVVQDMDDAFSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKFDYMGRSPRELSFKKGASLLLYHRASEDWWEGRHNGVDGLIPHQYIVVQDMDDAFSDS
640 650 660 670 680 690
790 800 810 820 830 840
pF1KA0 LSQKADSEASSGPLLDDKASSKNDLQSPTEHISDYGFGGVMGRVRLRSDGAAIPRRRSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSQKADSEASSGPLLDDKASSKNDLQSPTEHISDYGFGGVMGRVRLRSDGAAIPRRRSGG
700 710 720 730 740 750
850 860 870 880 890 900
pF1KA0 DTHSPPRGLGPSIDTPPRAAACPSSPHKIPLTRGRIESPEKRRMATFGSAGSINYPDKKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTHSPPRGLGPSIDTPPRAAACPSSPHKIPLTRGRIESPEKRRMATFGSAGSINYPDKKA
760 770 780 790 800 810
910 920 930 940 950 960
pF1KA0 LSEGHSMRSTCGSTRHSSLGDHKSLEAEALAEDIEKTMSTALHELRELERQNTVKQAPDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSEGHSMRSTCGSTRHSSLGDHKSLEAEALAEDIEKTMSTALHELRELERQNTVKQAPDV
820 830 840 850 860 870
970 980 990 1000 1010 1020
pF1KA0 VLDTLEPLKNPPGPVSSEPASPLHTIVIRDPDAAMRRSSSSSTEMMTTFKPALSARLAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLDTLEPLKNPPGPVSSEPASPLHTIVIRDPDAAMRRSSSSSTEMMTTFKPALSARLAGA
880 890 900 910 920 930
1030 1040 1050 1060 1070
pF1KA0 QLRPPPMRPVRPVVQHRSSSSSSSGVGSPAVTPTEKMFPNSSADKSGTM
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLRPPPMRPVRPVVQHRSSSSSSSGVGSPAVTPTEKMFPNSSADKSGTM
940 950 960 970
>>XP_016863065 (OMIM: 606525) PREDICTED: SLIT-ROBO Rho G (979 aa)
initn: 6234 init1: 3938 opt: 3938 Z-score: 2324.2 bits: 441.6 E(85289): 1e-122
Smith-Waterman score: 6189; 96.7% identity (97.0% similar) in 979 aa overlap (121-1075:1-979)
100 110 120 130 140 150
pF1KA0 YLLSPVNCWYLVLHQTRRESRDHATLNDIFMNNVIVRLSQISEDVIRLFKKSKEIGLQMH
::::::::::::::::::::::::::::::
XP_016 MNNVIVRLSQISEDVIRLFKKSKEIGLQMH
10 20 30
160 170 180 190 200 210
pF1KA0 EELLKVTNELYTVMKTYHMYHAESISAESKLKEAEKQEEKQFNKSGDLSMNLLRHEDRPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EELLKVTNELYTVMKTYHMYHAESISAESKLKEAEKQEEKQFNKSGDLSMNLLRHEDRPQ
40 50 60 70 80 90
220 230 240 250 260 270
pF1KA0 RRSSVKKIEKMKEKRQAKYSENKLKCTKARNDYLLNLAATNAAISKYYIHDVSDLIDCCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRSSVKKIEKMKEKRQAKYSENKLKCTKARNDYLLNLAATNAAISKYYIHDVSDLIDCCD
100 110 120 130 140 150
280 290 300 310 320 330
pF1KA0 LGFHASLARTFRTYLSAEYNLETSRHEGLDVIENAVDNLDSRSDKHTVMDMCNQVFCPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGFHASLARTFRTYLSAEYNLETSRHEGLDVIENAVDNLDSRSDKHTVMDMCNQVFCPPL
160 170 180 190 200 210
340 350 360 370 380 390
pF1KA0 KFEFQPHMGDEVCQVSAQQPVQTELLMRYHQLQSRLATLKIENEEVRKTLDATMQTLQDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFEFQPHMGDEVCQVSAQQPVQTELLMRYHQLQSRLATLKIENEEVRKTLDATMQTLQDM
220 230 240 250 260 270
400 410 420 430 440 450
pF1KA0 LTVEDFDVSDAFQHSRSTESVKSAASETYMSKINIAKRRANQQETEMFYFTKFKEYVNGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTVEDFDVSDAFQHSRSTESVKSAASETYMSKINIAKRRANQQETEMFYFTKFKEYVNGS
280 290 300 310 320 330
460 470 480
pF1KA0 NLITKLQAKHDLLKQTLGEGERAECGTTRG-------RRNARTRN---------------
::::::::::::::::::::::::::::: .. : :
XP_016 NLITKLQAKHDLLKQTLGEGERAECGTTRPPCLPPKPQKMRRPRPLSVYSHKLFNGSMEA
340 350 360 370 380 390
490 500 510 520 530 540
pF1KA0 --QDSGQAIPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNE
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIKDSGQAIPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNE
400 410 420 430 440 450
550 560 570 580 590 600
pF1KA0 RDINSVAGVLKLYFRGLENPLFPKERFQDLISTIKLENPAERVHQIQQILVTLPRVVIVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDINSVAGVLKLYFRGLENPLFPKERFQDLISTIKLENPAERVHQIQQILVTLPRVVIVV
460 470 480 490 500 510
610 620 630 640 650 660
pF1KA0 MRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVSCQAHINEVIKTIIIHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVSCQAHINEVIKTIIIHH
520 530 540 550 560 570
670 680 690 700 710 720
pF1KA0 EAIFPSPRELEGPVYEKCMAGGEEYCDSPHSEPGAIDEVDHDNGTEPHTSDEEVEQIEAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAIFPSPRELEGPVYEKCMAGGEEYCDSPHSEPGAIDEVDHDNGTEPHTSDEEVEQIEAI
580 590 600 610 620 630
730 740 750 760 770 780
pF1KA0 AKFDYMGRSPRELSFKKGASLLLYHRASEDWWEGRHNGVDGLIPHQYIVVQDMDDAFSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKFDYMGRSPRELSFKKGASLLLYHRASEDWWEGRHNGVDGLIPHQYIVVQDMDDAFSDS
640 650 660 670 680 690
790 800 810 820 830 840
pF1KA0 LSQKADSEASSGPLLDDKASSKNDLQSPTEHISDYGFGGVMGRVRLRSDGAAIPRRRSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSQKADSEASSGPLLDDKASSKNDLQSPTEHISDYGFGGVMGRVRLRSDGAAIPRRRSGG
700 710 720 730 740 750
850 860 870 880 890 900
pF1KA0 DTHSPPRGLGPSIDTPPRAAACPSSPHKIPLTRGRIESPEKRRMATFGSAGSINYPDKKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTHSPPRGLGPSIDTPPRAAACPSSPHKIPLTRGRIESPEKRRMATFGSAGSINYPDKKA
760 770 780 790 800 810
910 920 930 940 950 960
pF1KA0 LSEGHSMRSTCGSTRHSSLGDHKSLEAEALAEDIEKTMSTALHELRELERQNTVKQAPDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSEGHSMRSTCGSTRHSSLGDHKSLEAEALAEDIEKTMSTALHELRELERQNTVKQAPDV
820 830 840 850 860 870
970 980 990 1000 1010 1020
pF1KA0 VLDTLEPLKNPPGPVSSEPASPLHTIVIRDPDAAMRRSSSSSTEMMTTFKPALSARLAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLDTLEPLKNPPGPVSSEPASPLHTIVIRDPDAAMRRSSSSSTEMMTTFKPALSARLAGA
880 890 900 910 920 930
1030 1040 1050 1060 1070
pF1KA0 QLRPPPMRPVRPVVQHRSSSSSSSGVGSPAVTPTEKMFPNSSADKSGTM
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLRPPPMRPVRPVVQHRSSSSSSSGVGSPAVTPTEKMFPNSSADKSGTM
940 950 960 970
1075 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 18:50:15 2016 done: Wed Nov 2 18:50:17 2016
Total Scan time: 11.440 Total Display time: 0.350
Function used was FASTA [36.3.4 Apr, 2011]