Result of FASTA (omim) for
pF1KA0404
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0404, 1938 aa
1>>>pF1KA0404 1938 - 1938 aa - 1938 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.5986+/-0.000339; mu= 15.5035+/- 0.021
mean_var=158.0237+/-33.109, 0's: 0 Z-trim(120.0): 16 B-trim: 1161 in 1/57
Lambda= 0.102027
statistics sampled from 34637 (34653) to 34637 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.71), E-opt: 0.2 (0.406), width: 16
Scan time: 17.090
The best scores are: opt bits E(85289)
NP_055919 (OMIM: 616225) autophagy-related protein (1938) 13101 1941.6 0
XP_011543165 (OMIM: 616225) PREDICTED: autophagy-r (1940) 13087 1939.5 0
XP_005273907 (OMIM: 616225) PREDICTED: autophagy-r (1930) 13014 1928.8 0
XP_011543166 (OMIM: 616225) PREDICTED: autophagy-r (1935) 13002 1927.0 0
XP_005273906 (OMIM: 616225) PREDICTED: autophagy-r (1932) 13000 1926.7 0
XP_011543167 (OMIM: 616225) PREDICTED: autophagy-r (1875) 12621 1870.9 0
XP_011543168 (OMIM: 616225) PREDICTED: autophagy-r (1762) 11916 1767.1 0
XP_011543169 (OMIM: 616225) PREDICTED: autophagy-r (1346) 8778 1305.2 0
XP_011543170 (OMIM: 616225) PREDICTED: autophagy-r (1152) 7780 1158.2 0
NP_060506 (OMIM: 616226) autophagy-related protein (2078) 2276 348.3 5e-94
XP_016876886 (OMIM: 616226) PREDICTED: autophagy-r (1957) 2274 347.9 5.9e-94
XP_006720250 (OMIM: 616226) PREDICTED: autophagy-r (2077) 2274 348.0 6.1e-94
>>NP_055919 (OMIM: 616225) autophagy-related protein 2 h (1938 aa)
initn: 13101 init1: 13101 opt: 13101 Z-score: 10420.7 bits: 1941.6 E(85289): 0
Smith-Waterman score: 13101; 99.9% identity (99.9% similar) in 1938 aa overlap (1-1938:1-1938)
10 20 30 40 50 60
pF1KA0 MSRWLWPWSNCVKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MSRWLWPWSNCVKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 EVLESMESPLELVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRRGPAPGAADSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EVLESMESPLELVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRRGPAPGAADSQS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 WASCMTTSLQLAQECLRDGLPEPSEPPQPLEGLEMFAQTIETVLRRIKVTFLDTVVRVEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 WASCMTTSLQLAQECLRDGLPEPSEPPQPLEGLEMFAQTIETVLRRIKVTFLDTVVRVEH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 SPGDGERGVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQPPAFLHKLLQLAGVRLHYEELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SPGDGERGVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQPPAFLHKLLQLAGVRLHYEELP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 AQEEPPEPPLQIGSCSGYMELMVKLKQNEAFPGPKLEVAGQLGSLHLLLTPRQLQQLQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AQEEPPEPPLQIGSCSGYMELMVKLKQNEAFPGPKLEVAGQLGSLHLLLTPRQLQQLQEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LSAVSLTDHEGLADKLNKSRPLGAEDLWLIEQDLNQQLQAGAVAEPLSPDPLTNPLLNLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LSAVSLTDHEGLADKLNKSRPLGAEDLWLIEQDLNQQLQAGAVAEPLSPDPLTNPLLNLD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 NTDLFFSMAGLTSSVASALSELSLSDVDLASSVRSDMASRRLSAQAHPAGKMAPNPLLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NTDLFFSMAGLTSSVASALSELSLSDVDLASSVRSDMASRRLSAQAHPAGKMAPNPLLDT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 MRPDSLLKMTLGGVTLTLLQTSAPSSGPPDLATHFFTEFDATKDGPFGSRDFHHLRPRFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MRPDSLLKMTLGGVTLTLLQTSAPSSGPPDLATHFFTEFDATKDGPFGSRDFHHLRPRFQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 RACPCSHVRLTGTAVQLSWELRTGSRGRRTTSMEVHFGQLEVLECLWPRGTSEPEYTEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RACPCSHVRLTGTAVQLSWELRTGSRGRRTTSMEVHFGQLEVLECLWPRGTSEPEYTEIL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 TFPGTLGSQASARPCAHLRHTQILRRVPKSRPRRSVACHCHSELALDLANFQADVELGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TFPGTLGSQASARPCAHLRHTQILRRVPKSRPRRSVACHCHSELALDLANFQADVELGAL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 DRLAALLRLATVPAEPPAGLLTEPLPAMEQQTVFRLSAPRATLRLRFPIADLRPERDPWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
NP_055 DRLAALLRLATVPAEPPAGLLTEPLPAMEQQTVFRLSAPRATLRLRFPIADLRPEPDPWA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 GQAVRAEQLRLELSEPQFRSELSSGPGPPVPTHLELTCSDLHGIYEDGGKPPVPCLRVSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GQAVRAEQLRLELSEPQFRSELSSGPGPPVPTHLELTCSDLHGIYEDGGKPPVPCLRVSK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 ALDPKSTGRKYFLPQVVVTVNPQSSSTQWEVAPEKGEELELSVESPCELREPEPSPFSSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ALDPKSTGRKYFLPQVVVTVNPQSSSTQWEVAPEKGEELELSVESPCELREPEPSPFSSK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 RTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEVILPSVHIFLPSKEVYESIYNRINND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEVILPSVHIFLPSKEVYESIYNRINND
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 LLMWEPADLLPTPDPAAQPSGFPGPSGFWHDSFKMCKSAFKLANCFDLTPDSDSDDEDAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LLMWEPADLLPTPDPAAQPSGFPGPSGFWHDSFKMCKSAFKLANCFDLTPDSDSDDEDAH
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 FFSVGASGGPQAAAPEAPSLHLQSTFSTLVTVLKGRITALCETKDEGGKRLEAVHGELVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FFSVGASGGPQAAAPEAPSLHLQSTFSTLVTVLKGRITALCETKDEGGKRLEAVHGELVL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 DMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVDDYPLPSHLDLPSFAPPAQLAPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVDDYPLPSHLDLPSFAPPAQLAPT
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 IYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLDPHKNVKEFLVTLRLHKATLRHYMAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLDPHKNVKEFLVTLRLHKATLRHYMAL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 PEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTHLFSCSVDYRPLYLPVRVLITAETFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTHLFSCSVDYRPLYLPVRVLITAETFT
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 LSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDLRRDYVCVLDVDLLELVIKTWKGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDLRRDYVCVLDVDLLELVIKTWKGST
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 EGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVMSTGDLHPPPRPPSPTEIAGQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVMSTGDLHPPPRPPSPTEIAGQKL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 SESPASLPSCPPVETALINQRDLADALLDTERSLRELAQPSGGHLPQASPISVYLFPGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SESPASLPSCPPVETALINQRDLADALLDTERSLRELAQPSGGHLPQASPISVYLFPGER
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 SGAPPPSPPVGGPAGSLGSCSEEKEDEREEEGDGDTLDSDEFCILDAPGLGIPPRDGEPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SGAPPPSPPVGGPAGSLGSCSEEKEDEREEEGDGDTLDSDEFCILDAPGLGIPPRDGEPV
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 VTQLHPGPIVVRDGYFSRPIGSTDLLRAPAHFPVPSTRVVLREVSLVWHLYGGRDFGPHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VTQLHPGPIVVRDGYFSRPIGSTDLLRAPAHFPVPSTRVVLREVSLVWHLYGGRDFGPHP
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 GHRARTGLSGPRSSPSRCSGPNRPQNSWRTQGGSGRQHHVLMEIQLSKVSFQHEVYPAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GHRARTGLSGPRSSPSRCSGPNRPQNSWRTQGGSGRQHHVLMEIQLSKVSFQHEVYPAEP
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 ATGPAAPSQELEERPLSRQVFIVQELEVRDRLASSQINKFLYLHTSERMPRRAHSNMLTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ATGPAAPSQELEERPLSRQVFIVQELEVRDRLASSQINKFLYLHTSERMPRRAHSNMLTI
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KA0 KALHVAPTTNLGGPECCLRVSLMPLRLNVDQDALFFLKDFFTSLVAGINPVVPGETSAEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KALHVAPTTNLGGPECCLRVSLMPLRLNVDQDALFFLKDFFTSLVAGINPVVPGETSAEA
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KA0 RPETRAQPSSPLEGQAEGVETTGSQEAPGGGHSPSPPDQQPIYFREFRFTSEVPIWLDYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RPETRAQPSSPLEGQAEGVETTGSQEAPGGGHSPSPPDQQPIYFREFRFTSEVPIWLDYH
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KA0 GKHVTMDQVGTFAGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLGYALNEWLQDIRKNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GKHVTMDQVGTFAGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLGYALNEWLQDIRKNQ
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KA0 LPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLMRGLQRGAASFGSSTASAALEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLMRGLQRGAASFGSSTASAALEL
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KA0 SNRLVQAIQATAETVYDILSPAAPVSRSLQDKRSARRLRRGQQPADLREGVAKAYDTVRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SNRLVQAIQATAETVYDILSPAAPVSRSLQDKRSARRLRRGQQPADLREGVAKAYDTVRE
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KA0 GILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVKPLILATEATSSLLGGMRNQIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVKPLILATEATSSLLGGMRNQIV
1870 1880 1890 1900 1910 1920
1930
pF1KA0 PDAHKDHALKWRSDSAQD
::::::::::::::::::
NP_055 PDAHKDHALKWRSDSAQD
1930
>>XP_011543165 (OMIM: 616225) PREDICTED: autophagy-relat (1940 aa)
initn: 8544 init1: 8506 opt: 13087 Z-score: 10409.6 bits: 1939.5 E(85289): 0
Smith-Waterman score: 13087; 99.8% identity (99.8% similar) in 1940 aa overlap (1-1938:1-1940)
10 20 30 40 50 60
pF1KA0 MSRWLWPWSNCVKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSRWLWPWSNCVKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 EVLESMESPLELVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRRGPAPGAADSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVLESMESPLELVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRRGPAPGAADSQS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 WASCMTTSLQLAQECLRDGLPEPSEPPQPLEGLEMFAQTIETVLRRIKVTFLDTVVRVEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WASCMTTSLQLAQECLRDGLPEPSEPPQPLEGLEMFAQTIETVLRRIKVTFLDTVVRVEH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 SPGDGERGVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQPPAFLHKLLQLAGVRLHYEELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPGDGERGVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQPPAFLHKLLQLAGVRLHYEELP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 AQEEPPEPPLQIGSCSGYMELMVKLKQNEAFPGPKLEVAGQLGSLHLLLTPRQLQQLQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQEEPPEPPLQIGSCSGYMELMVKLKQNEAFPGPKLEVAGQLGSLHLLLTPRQLQQLQEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LSAVSLTDHEGLADKLNKSRPLGAEDLWLIEQDLNQQLQAGAVAEPLSPDPLTNPLLNLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSAVSLTDHEGLADKLNKSRPLGAEDLWLIEQDLNQQLQAGAVAEPLSPDPLTNPLLNLD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 NTDLFFSMAGLTSSVASALSELSLSDVDLASSVRSDMASRRLSAQAHPAGKMAPNPLLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTDLFFSMAGLTSSVASALSELSLSDVDLASSVRSDMASRRLSAQAHPAGKMAPNPLLDT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 MRPDSLLKMTLGGVTLTLLQTSAPSSGPPDLATHFFTEFDATKDGPFGSRDFHHLRPRFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRPDSLLKMTLGGVTLTLLQTSAPSSGPPDLATHFFTEFDATKDGPFGSRDFHHLRPRFQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 RACPCSHVRLTGTAVQLSWELRTGSRGRRTTSMEVHFGQLEVLECLWPRGTSEPEYTEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RACPCSHVRLTGTAVQLSWELRTGSRGRRTTSMEVHFGQLEVLECLWPRGTSEPEYTEIL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 TFPGTLGSQASARPCAHLRHTQILRRVPKSRPRRSVACHCHSELALDLANFQADVELGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFPGTLGSQASARPCAHLRHTQILRRVPKSRPRRSVACHCHSELALDLANFQADVELGAL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 DRLAALLRLATVPAEPPAGLLTEPLPAMEQQTVFRLSAPRATLRLRFPIADLRPERDPWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
XP_011 DRLAALLRLATVPAEPPAGLLTEPLPAMEQQTVFRLSAPRATLRLRFPIADLRPEPDPWA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 GQAVRAEQLRLELSEPQFRSELSSGPGPPVPTHLELTCSDLHGIYEDGGKPPVPCLRVSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQAVRAEQLRLELSEPQFRSELSSGPGPPVPTHLELTCSDLHGIYEDGGKPPVPCLRVSK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 ALDPKSTGRKYFLPQVVVTVNPQSSSTQWEVAPEKGEELELSVESPCELREPEPSPFSSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALDPKSTGRKYFLPQVVVTVNPQSSSTQWEVAPEKGEELELSVESPCELREPEPSPFSSK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 RTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEVILPSVHIFLPSKEVYESIYNRINND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEVILPSVHIFLPSKEVYESIYNRINND
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 LLMWEPADLLPTPDPAAQPSGFPGPSGFWHDSFKMCKSAFKLANCFDLTPDSDSDDEDAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLMWEPADLLPTPDPAAQPSGFPGPSGFWHDSFKMCKSAFKLANCFDLTPDSDSDDEDAH
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 FFSVGASGGPQAAAPEAPSLHLQSTFSTLVTVLKGRITALCETKDEGGKRLEAVHGELVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FFSVGASGGPQAAAPEAPSLHLQSTFSTLVTVLKGRITALCETKDEGGKRLEAVHGELVL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 DMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVDDYPLPSHLDLPSFAPPAQLAPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVDDYPLPSHLDLPSFAPPAQLAPT
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 IYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLDPHKNVKEFLVTLRLHKATLRHYMAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLDPHKNVKEFLVTLRLHKATLRHYMAL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 PEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTHLFSCSVDYRPLYLPVRVLITAETFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTHLFSCSVDYRPLYLPVRVLITAETFT
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 LSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDLRRDYVCVLDVDLLELVIKTWKGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDLRRDYVCVLDVDLLELVIKTWKGST
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250
pF1KA0 EGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVMSTGDLHPPPRPPSPTEIAGQK-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVMSTGDLHPPPRPPSPTEIAGQKV
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KA0 -LSESPASLPSCPPVETALINQRDLADALLDTERSLRELAQPSGGHLPQASPISVYLFPG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLSESPASLPSCPPVETALINQRDLADALLDTERSLRELAQPSGGHLPQASPISVYLFPG
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KA0 ERSGAPPPSPPVGGPAGSLGSCSEEKEDEREEEGDGDTLDSDEFCILDAPGLGIPPRDGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERSGAPPPSPPVGGPAGSLGSCSEEKEDEREEEGDGDTLDSDEFCILDAPGLGIPPRDGE
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410 1420 1430
pF1KA0 PVVTQLHPGPIVVRDGYFSRPIGSTDLLRAPAHFPVPSTRVVLREVSLVWHLYGGRDFGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVVTQLHPGPIVVRDGYFSRPIGSTDLLRAPAHFPVPSTRVVLREVSLVWHLYGGRDFGP
1390 1400 1410 1420 1430 1440
1440 1450 1460 1470 1480 1490
pF1KA0 HPGHRARTGLSGPRSSPSRCSGPNRPQNSWRTQGGSGRQHHVLMEIQLSKVSFQHEVYPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPGHRARTGLSGPRSSPSRCSGPNRPQNSWRTQGGSGRQHHVLMEIQLSKVSFQHEVYPA
1450 1460 1470 1480 1490 1500
1500 1510 1520 1530 1540 1550
pF1KA0 EPATGPAAPSQELEERPLSRQVFIVQELEVRDRLASSQINKFLYLHTSERMPRRAHSNML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPATGPAAPSQELEERPLSRQVFIVQELEVRDRLASSQINKFLYLHTSERMPRRAHSNML
1510 1520 1530 1540 1550 1560
1560 1570 1580 1590 1600 1610
pF1KA0 TIKALHVAPTTNLGGPECCLRVSLMPLRLNVDQDALFFLKDFFTSLVAGINPVVPGETSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIKALHVAPTTNLGGPECCLRVSLMPLRLNVDQDALFFLKDFFTSLVAGINPVVPGETSA
1570 1580 1590 1600 1610 1620
1620 1630 1640 1650 1660 1670
pF1KA0 EARPETRAQPSSPLEGQAEGVETTGSQEAPGGGHSPSPPDQQPIYFREFRFTSEVPIWLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EARPETRAQPSSPLEGQAEGVETTGSQEAPGGGHSPSPPDQQPIYFREFRFTSEVPIWLD
1630 1640 1650 1660 1670 1680
1680 1690 1700 1710 1720 1730
pF1KA0 YHGKHVTMDQVGTFAGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLGYALNEWLQDIRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YHGKHVTMDQVGTFAGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLGYALNEWLQDIRK
1690 1700 1710 1720 1730 1740
1740 1750 1760 1770 1780 1790
pF1KA0 NQLPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLMRGLQRGAASFGSSTASAAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQLPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLMRGLQRGAASFGSSTASAAL
1750 1760 1770 1780 1790 1800
1800 1810 1820 1830 1840 1850
pF1KA0 ELSNRLVQAIQATAETVYDILSPAAPVSRSLQDKRSARRLRRGQQPADLREGVAKAYDTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELSNRLVQAIQATAETVYDILSPAAPVSRSLQDKRSARRLRRGQQPADLREGVAKAYDTV
1810 1820 1830 1840 1850 1860
1860 1870 1880 1890 1900 1910
pF1KA0 REGILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVKPLILATEATSSLLGGMRNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REGILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVKPLILATEATSSLLGGMRNQ
1870 1880 1890 1900 1910 1920
1920 1930
pF1KA0 IVPDAHKDHALKWRSDSAQD
::::::::::::::::::::
XP_011 IVPDAHKDHALKWRSDSAQD
1930 1940
>>XP_005273907 (OMIM: 616225) PREDICTED: autophagy-relat (1930 aa)
initn: 13026 init1: 7075 opt: 13014 Z-score: 10351.6 bits: 1928.8 E(85289): 0
Smith-Waterman score: 13014; 99.5% identity (99.5% similar) in 1938 aa overlap (1-1938:1-1930)
10 20 30 40 50 60
pF1KA0 MSRWLWPWSNCVKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSRWLWPWSNCVKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 EVLESMESPLELVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRRGPAPGAADSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVLESMESPLELVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRRGPAPGAADSQS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 WASCMTTSLQLAQECLRDGLPEPSEPPQPLEGLEMFAQTIETVLRRIKVTFLDTVVRVEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WASCMTTSLQLAQECLRDGLPEPSEPPQPLEGLEMFAQTIETVLRRIKVTFLDTVVRVEH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 SPGDGERGVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQPPAFLHKLLQLAGVRLHYEELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPGDGERGVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQPPAFLHKLLQLAGVRLHYEELP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 AQEEPPEPPLQIGSCSGYMELMVKLKQNEAFPGPKLEVAGQLGSLHLLLTPRQLQQLQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQEEPPEPPLQIGSCSGYMELMVKLKQNEAFPGPKLEVAGQLGSLHLLLTPRQLQQLQEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LSAVSLTDHEGLADKLNKSRPLGAEDLWLIEQDLNQQLQAGAVAEPLSPDPLTNPLLNLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSAVSLTDHEGLADKLNKSRPLGAEDLWLIEQDLNQQLQAGAVAEPLSPDPLTNPLLNLD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 NTDLFFSMAGLTSSVASALSELSLSDVDLASSVRSDMASRRLSAQAHPAGKMAPNPLLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NTDLFFSMAGLTSSVASALSELSLSDVDLASSVRSDMASRRLSAQAHPAGKMAPNPLLDT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 MRPDSLLKMTLGGVTLTLLQTSAPSSGPPDLATHFFTEFDATKDGPFGSRDFHHLRPRFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MRPDSLLKMTLGGVTLTLLQTSAPSSGPPDLATHFFTEFDATKDGPFGSRDFHHLRPRFQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 RACPCSHVRLTGTAVQLSWELRTGSRGRRTTSMEVHFGQLEVLECLWPRGTSEPEYTEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RACPCSHVRLTGTAVQLSWELRTGSRGRRTTSMEVHFGQLEVLECLWPRGTSEPEYTEIL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 TFPGTLGSQASARPCAHLRHTQILRRVPKSRPRRSVACHCHSELALDLANFQADVELGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TFPGTLGSQASARPCAHLRHTQILRRVPKSRPRRSVACHCHSELALDLANFQADVELGAL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 DRLAALLRLATVPAEPPAGLLTEPLPAMEQQTVFRLSAPRATLRLRFPIADLRPERDPWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
XP_005 DRLAALLRLATVPAEPPAGLLTEPLPAMEQQTVFRLSAPRATLRLRFPIADLRPEPDPWA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 GQAVRAEQLRLELSEPQFRSELSSGPGPPVPTHLELTCSDLHGIYEDGGKPPVPCLRVSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GQAVRAEQLRLELSEPQFRSELSSGPGPPVPTHLELTCSDLHGIYEDGGKPPVPCLRVSK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 ALDPKSTGRKYFLPQVVVTVNPQSSSTQWEVAPEKGEELELSVESPCELREPEPSPFSSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALDPKSTGRKYFLPQVVVTVNPQSSSTQWEVAPEKGEELELSVESPCELREPEPSPFSSK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 RTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEVILPSVHIFLPSKEVYESIYNRINND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEVILPSVHIFLPSKEVYESIYNRINND
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 LLMWEPADLLPTPDPAAQPSGFPGPSGFWHDSFKMCKSAFKLANCFDLTPDSDSDDEDAH
:::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_005 LLMWEPADLLPTPDPAAQPSGFPGPSGFWHDSFKMCKSAFKL--------DSDSDDEDAH
850 860 870 880 890
910 920 930 940 950 960
pF1KA0 FFSVGASGGPQAAAPEAPSLHLQSTFSTLVTVLKGRITALCETKDEGGKRLEAVHGELVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FFSVGASGGPQAAAPEAPSLHLQSTFSTLVTVLKGRITALCETKDEGGKRLEAVHGELVL
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KA0 DMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVDDYPLPSHLDLPSFAPPAQLAPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVDDYPLPSHLDLPSFAPPAQLAPT
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KA0 IYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLDPHKNVKEFLVTLRLHKATLRHYMAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLDPHKNVKEFLVTLRLHKATLRHYMAL
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KA0 PEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTHLFSCSVDYRPLYLPVRVLITAETFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTHLFSCSVDYRPLYLPVRVLITAETFT
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KA0 LSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDLRRDYVCVLDVDLLELVIKTWKGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDLRRDYVCVLDVDLLELVIKTWKGST
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KA0 EGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVMSTGDLHPPPRPPSPTEIAGQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVMSTGDLHPPPRPPSPTEIAGQKL
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KA0 SESPASLPSCPPVETALINQRDLADALLDTERSLRELAQPSGGHLPQASPISVYLFPGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SESPASLPSCPPVETALINQRDLADALLDTERSLRELAQPSGGHLPQASPISVYLFPGER
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KA0 SGAPPPSPPVGGPAGSLGSCSEEKEDEREEEGDGDTLDSDEFCILDAPGLGIPPRDGEPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGAPPPSPPVGGPAGSLGSCSEEKEDEREEEGDGDTLDSDEFCILDAPGLGIPPRDGEPV
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KA0 VTQLHPGPIVVRDGYFSRPIGSTDLLRAPAHFPVPSTRVVLREVSLVWHLYGGRDFGPHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTQLHPGPIVVRDGYFSRPIGSTDLLRAPAHFPVPSTRVVLREVSLVWHLYGGRDFGPHP
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490 1500
pF1KA0 GHRARTGLSGPRSSPSRCSGPNRPQNSWRTQGGSGRQHHVLMEIQLSKVSFQHEVYPAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GHRARTGLSGPRSSPSRCSGPNRPQNSWRTQGGSGRQHHVLMEIQLSKVSFQHEVYPAEP
1440 1450 1460 1470 1480 1490
1510 1520 1530 1540 1550 1560
pF1KA0 ATGPAAPSQELEERPLSRQVFIVQELEVRDRLASSQINKFLYLHTSERMPRRAHSNMLTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATGPAAPSQELEERPLSRQVFIVQELEVRDRLASSQINKFLYLHTSERMPRRAHSNMLTI
1500 1510 1520 1530 1540 1550
1570 1580 1590 1600 1610 1620
pF1KA0 KALHVAPTTNLGGPECCLRVSLMPLRLNVDQDALFFLKDFFTSLVAGINPVVPGETSAEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KALHVAPTTNLGGPECCLRVSLMPLRLNVDQDALFFLKDFFTSLVAGINPVVPGETSAEA
1560 1570 1580 1590 1600 1610
1630 1640 1650 1660 1670 1680
pF1KA0 RPETRAQPSSPLEGQAEGVETTGSQEAPGGGHSPSPPDQQPIYFREFRFTSEVPIWLDYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RPETRAQPSSPLEGQAEGVETTGSQEAPGGGHSPSPPDQQPIYFREFRFTSEVPIWLDYH
1620 1630 1640 1650 1660 1670
1690 1700 1710 1720 1730 1740
pF1KA0 GKHVTMDQVGTFAGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLGYALNEWLQDIRKNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GKHVTMDQVGTFAGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLGYALNEWLQDIRKNQ
1680 1690 1700 1710 1720 1730
1750 1760 1770 1780 1790 1800
pF1KA0 LPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLMRGLQRGAASFGSSTASAALEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLMRGLQRGAASFGSSTASAALEL
1740 1750 1760 1770 1780 1790
1810 1820 1830 1840 1850 1860
pF1KA0 SNRLVQAIQATAETVYDILSPAAPVSRSLQDKRSARRLRRGQQPADLREGVAKAYDTVRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SNRLVQAIQATAETVYDILSPAAPVSRSLQDKRSARRLRRGQQPADLREGVAKAYDTVRE
1800 1810 1820 1830 1840 1850
1870 1880 1890 1900 1910 1920
pF1KA0 GILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVKPLILATEATSSLLGGMRNQIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVKPLILATEATSSLLGGMRNQIV
1860 1870 1880 1890 1900 1910
1930
pF1KA0 PDAHKDHALKWRSDSAQD
::::::::::::::::::
XP_005 PDAHKDHALKWRSDSAQD
1920 1930
>>XP_011543166 (OMIM: 616225) PREDICTED: autophagy-relat (1935 aa)
initn: 10553 init1: 5967 opt: 13002 Z-score: 10342.0 bits: 1927.0 E(85289): 0
Smith-Waterman score: 13002; 99.4% identity (99.5% similar) in 1940 aa overlap (1-1938:1-1935)
10 20 30 40 50 60
pF1KA0 MSRWLWPWSNCVKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSRWLWPWSNCVKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 EVLESMESPLELVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRRGPAPGAADSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVLESMESPLELVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRRGPAPGAADSQS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 WASCMTTSLQLAQECLRDGLPEPSEPPQPLEGLEMFAQTIETVLRRIKVTFLDTVVRVEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WASCMTTSLQLAQECLRDGLPEPSEPPQPLEGLEMFAQTIETVLRRIKVTFLDTVVRVEH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 SPGDGERGVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQPPAFLHKLLQLAGVRLHYEELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPGDGERGVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQPPAFLHKLLQLAGVRLHYEELP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 AQEEPPEPPLQIGSCSGYMELMVKLKQNEAFPGPKLEVAGQLGSLHLLLTPRQLQQLQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQEEPPEPPLQIGSCSGYMELMVKLKQNEAFPGPKLEVAGQLGSLHLLLTPRQLQQLQEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LSAVSLTDHEGLADKLNKSRPLGAEDLWLIEQDLNQQLQAGAVAEPLSPDPLTNPLLNLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSAVSLTDHEGLADKLNKSRPLGAEDLWLIEQDLNQQLQAGAVAEPLSPDPLTNPLLNLD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 NTDLFFSMAGLTSSVASALSELSLSDVDLASSVRSDMASRRLSAQAHPAGKMAPNPLLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTDLFFSMAGLTSSVASALSELSLSDVDLASSVRSDMASRRLSAQAHPAGKMAPNPLLDT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 MRPDSLLKMTLGGVTLTLLQTSAPSSGPPDLATHFFTEFDATKDGPFGSRDFHHLRPRFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRPDSLLKMTLGGVTLTLLQTSAPSSGPPDLATHFFTEFDATKDGPFGSRDFHHLRPRFQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 RACPCSHVRLTGTAVQLSWELRTGSRGRRTTSMEVHFGQLEVLECLWPRGTSEPEYTEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RACPCSHVRLTGTAVQLSWELRTGSRGRRTTSMEVHFGQLEVLECLWPRGTSEPEYTEIL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 TFPGTLGSQASARPCAHLRHTQILRRVPKSRPRRSVACHCHSELALDLANFQADVELGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFPGTLGSQASARPCAHLRHTQILRRVPKSRPRRSVACHCHSELALDLANFQADVELGAL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 DRLAALLRLATVPAEPPAGLLTEPLPAMEQQTVFRLSAPRATLRLRFPIADLRPERDPWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
XP_011 DRLAALLRLATVPAEPPAGLLTEPLPAMEQQTVFRLSAPRATLRLRFPIADLRPEPDPWA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 GQAVRAEQLRLELSEPQFRSELSSGPGPPVPTHLELTCSDLHGIYEDGGKPPVPCLRVSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQAVRAEQLRLELSEPQFRSELSSGPGPPVPTHLELTCSDLHGIYEDGGKPPVPCLRVSK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 ALDPKSTGRKYFLPQVVVTVNPQSSSTQWEVAPEKGEELELSVESPCELREPEPSPFSSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALDPKSTGRKYFLPQVVVTVNPQSSSTQWEVAPEKGEELELSVESPCELREPEPSPFSSK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 RTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEVILPSVHIFLPSKEVYESIYNRINND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEVILPSVHIFLPSKEVYESIYNRINND
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 LLMWEPADLLPTPDPAAQPSGFPGPSGFWHDSFKMCKSAFKLANCFDLTPDSDSDDEDAH
::::::::::::::::::::::::::::::::::::::::::. ::::::::::
XP_011 LLMWEPADLLPTPDPAAQPSGFPGPSGFWHDSFKMCKSAFKLG-----MRDSDSDDEDAH
850 860 870 880 890
910 920 930 940 950 960
pF1KA0 FFSVGASGGPQAAAPEAPSLHLQSTFSTLVTVLKGRITALCETKDEGGKRLEAVHGELVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FFSVGASGGPQAAAPEAPSLHLQSTFSTLVTVLKGRITALCETKDEGGKRLEAVHGELVL
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KA0 DMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVDDYPLPSHLDLPSFAPPAQLAPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVDDYPLPSHLDLPSFAPPAQLAPT
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KA0 IYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLDPHKNVKEFLVTLRLHKATLRHYMAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLDPHKNVKEFLVTLRLHKATLRHYMAL
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KA0 PEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTHLFSCSVDYRPLYLPVRVLITAETFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTHLFSCSVDYRPLYLPVRVLITAETFT
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KA0 LSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDLRRDYVCVLDVDLLELVIKTWKGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDLRRDYVCVLDVDLLELVIKTWKGST
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250
pF1KA0 EGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVMSTGDLHPPPRPPSPTEIAGQK-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVMSTGDLHPPPRPPSPTEIAGQKV
1200 1210 1220 1230 1240 1250
1260 1270 1280 1290 1300 1310
pF1KA0 -LSESPASLPSCPPVETALINQRDLADALLDTERSLRELAQPSGGHLPQASPISVYLFPG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLSESPASLPSCPPVETALINQRDLADALLDTERSLRELAQPSGGHLPQASPISVYLFPG
1260 1270 1280 1290 1300 1310
1320 1330 1340 1350 1360 1370
pF1KA0 ERSGAPPPSPPVGGPAGSLGSCSEEKEDEREEEGDGDTLDSDEFCILDAPGLGIPPRDGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERSGAPPPSPPVGGPAGSLGSCSEEKEDEREEEGDGDTLDSDEFCILDAPGLGIPPRDGE
1320 1330 1340 1350 1360 1370
1380 1390 1400 1410 1420 1430
pF1KA0 PVVTQLHPGPIVVRDGYFSRPIGSTDLLRAPAHFPVPSTRVVLREVSLVWHLYGGRDFGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVVTQLHPGPIVVRDGYFSRPIGSTDLLRAPAHFPVPSTRVVLREVSLVWHLYGGRDFGP
1380 1390 1400 1410 1420 1430
1440 1450 1460 1470 1480 1490
pF1KA0 HPGHRARTGLSGPRSSPSRCSGPNRPQNSWRTQGGSGRQHHVLMEIQLSKVSFQHEVYPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPGHRARTGLSGPRSSPSRCSGPNRPQNSWRTQGGSGRQHHVLMEIQLSKVSFQHEVYPA
1440 1450 1460 1470 1480 1490
1500 1510 1520 1530 1540 1550
pF1KA0 EPATGPAAPSQELEERPLSRQVFIVQELEVRDRLASSQINKFLYLHTSERMPRRAHSNML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPATGPAAPSQELEERPLSRQVFIVQELEVRDRLASSQINKFLYLHTSERMPRRAHSNML
1500 1510 1520 1530 1540 1550
1560 1570 1580 1590 1600 1610
pF1KA0 TIKALHVAPTTNLGGPECCLRVSLMPLRLNVDQDALFFLKDFFTSLVAGINPVVPGETSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIKALHVAPTTNLGGPECCLRVSLMPLRLNVDQDALFFLKDFFTSLVAGINPVVPGETSA
1560 1570 1580 1590 1600 1610
1620 1630 1640 1650 1660 1670
pF1KA0 EARPETRAQPSSPLEGQAEGVETTGSQEAPGGGHSPSPPDQQPIYFREFRFTSEVPIWLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EARPETRAQPSSPLEGQAEGVETTGSQEAPGGGHSPSPPDQQPIYFREFRFTSEVPIWLD
1620 1630 1640 1650 1660 1670
1680 1690 1700 1710 1720 1730
pF1KA0 YHGKHVTMDQVGTFAGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLGYALNEWLQDIRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YHGKHVTMDQVGTFAGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLGYALNEWLQDIRK
1680 1690 1700 1710 1720 1730
1740 1750 1760 1770 1780 1790
pF1KA0 NQLPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLMRGLQRGAASFGSSTASAAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQLPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLMRGLQRGAASFGSSTASAAL
1740 1750 1760 1770 1780 1790
1800 1810 1820 1830 1840 1850
pF1KA0 ELSNRLVQAIQATAETVYDILSPAAPVSRSLQDKRSARRLRRGQQPADLREGVAKAYDTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELSNRLVQAIQATAETVYDILSPAAPVSRSLQDKRSARRLRRGQQPADLREGVAKAYDTV
1800 1810 1820 1830 1840 1850
1860 1870 1880 1890 1900 1910
pF1KA0 REGILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVKPLILATEATSSLLGGMRNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REGILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVKPLILATEATSSLLGGMRNQ
1860 1870 1880 1890 1900 1910
1920 1930
pF1KA0 IVPDAHKDHALKWRSDSAQD
::::::::::::::::::::
XP_011 IVPDAHKDHALKWRSDSAQD
1920 1930
>>XP_005273906 (OMIM: 616225) PREDICTED: autophagy-relat (1932 aa)
initn: 10551 init1: 5965 opt: 13000 Z-score: 10340.4 bits: 1926.7 E(85289): 0
Smith-Waterman score: 13000; 99.4% identity (99.4% similar) in 1940 aa overlap (1-1938:1-1932)
10 20 30 40 50 60
pF1KA0 MSRWLWPWSNCVKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSRWLWPWSNCVKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 EVLESMESPLELVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRRGPAPGAADSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVLESMESPLELVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRRGPAPGAADSQS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 WASCMTTSLQLAQECLRDGLPEPSEPPQPLEGLEMFAQTIETVLRRIKVTFLDTVVRVEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WASCMTTSLQLAQECLRDGLPEPSEPPQPLEGLEMFAQTIETVLRRIKVTFLDTVVRVEH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 SPGDGERGVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQPPAFLHKLLQLAGVRLHYEELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPGDGERGVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQPPAFLHKLLQLAGVRLHYEELP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 AQEEPPEPPLQIGSCSGYMELMVKLKQNEAFPGPKLEVAGQLGSLHLLLTPRQLQQLQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQEEPPEPPLQIGSCSGYMELMVKLKQNEAFPGPKLEVAGQLGSLHLLLTPRQLQQLQEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LSAVSLTDHEGLADKLNKSRPLGAEDLWLIEQDLNQQLQAGAVAEPLSPDPLTNPLLNLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSAVSLTDHEGLADKLNKSRPLGAEDLWLIEQDLNQQLQAGAVAEPLSPDPLTNPLLNLD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 NTDLFFSMAGLTSSVASALSELSLSDVDLASSVRSDMASRRLSAQAHPAGKMAPNPLLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NTDLFFSMAGLTSSVASALSELSLSDVDLASSVRSDMASRRLSAQAHPAGKMAPNPLLDT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 MRPDSLLKMTLGGVTLTLLQTSAPSSGPPDLATHFFTEFDATKDGPFGSRDFHHLRPRFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MRPDSLLKMTLGGVTLTLLQTSAPSSGPPDLATHFFTEFDATKDGPFGSRDFHHLRPRFQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 RACPCSHVRLTGTAVQLSWELRTGSRGRRTTSMEVHFGQLEVLECLWPRGTSEPEYTEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RACPCSHVRLTGTAVQLSWELRTGSRGRRTTSMEVHFGQLEVLECLWPRGTSEPEYTEIL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 TFPGTLGSQASARPCAHLRHTQILRRVPKSRPRRSVACHCHSELALDLANFQADVELGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TFPGTLGSQASARPCAHLRHTQILRRVPKSRPRRSVACHCHSELALDLANFQADVELGAL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 DRLAALLRLATVPAEPPAGLLTEPLPAMEQQTVFRLSAPRATLRLRFPIADLRPERDPWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
XP_005 DRLAALLRLATVPAEPPAGLLTEPLPAMEQQTVFRLSAPRATLRLRFPIADLRPEPDPWA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 GQAVRAEQLRLELSEPQFRSELSSGPGPPVPTHLELTCSDLHGIYEDGGKPPVPCLRVSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GQAVRAEQLRLELSEPQFRSELSSGPGPPVPTHLELTCSDLHGIYEDGGKPPVPCLRVSK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 ALDPKSTGRKYFLPQVVVTVNPQSSSTQWEVAPEKGEELELSVESPCELREPEPSPFSSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALDPKSTGRKYFLPQVVVTVNPQSSSTQWEVAPEKGEELELSVESPCELREPEPSPFSSK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 RTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEVILPSVHIFLPSKEVYESIYNRINND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEVILPSVHIFLPSKEVYESIYNRINND
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 LLMWEPADLLPTPDPAAQPSGFPGPSGFWHDSFKMCKSAFKLANCFDLTPDSDSDDEDAH
:::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_005 LLMWEPADLLPTPDPAAQPSGFPGPSGFWHDSFKMCKSAFKL--------DSDSDDEDAH
850 860 870 880 890
910 920 930 940 950 960
pF1KA0 FFSVGASGGPQAAAPEAPSLHLQSTFSTLVTVLKGRITALCETKDEGGKRLEAVHGELVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FFSVGASGGPQAAAPEAPSLHLQSTFSTLVTVLKGRITALCETKDEGGKRLEAVHGELVL
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KA0 DMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVDDYPLPSHLDLPSFAPPAQLAPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVDDYPLPSHLDLPSFAPPAQLAPT
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KA0 IYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLDPHKNVKEFLVTLRLHKATLRHYMAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLDPHKNVKEFLVTLRLHKATLRHYMAL
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KA0 PEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTHLFSCSVDYRPLYLPVRVLITAETFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTHLFSCSVDYRPLYLPVRVLITAETFT
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KA0 LSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDLRRDYVCVLDVDLLELVIKTWKGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDLRRDYVCVLDVDLLELVIKTWKGST
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250
pF1KA0 EGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVMSTGDLHPPPRPPSPTEIAGQK-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVMSTGDLHPPPRPPSPTEIAGQKV
1200 1210 1220 1230 1240 1250
1260 1270 1280 1290 1300 1310
pF1KA0 -LSESPASLPSCPPVETALINQRDLADALLDTERSLRELAQPSGGHLPQASPISVYLFPG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLSESPASLPSCPPVETALINQRDLADALLDTERSLRELAQPSGGHLPQASPISVYLFPG
1260 1270 1280 1290 1300 1310
1320 1330 1340 1350 1360 1370
pF1KA0 ERSGAPPPSPPVGGPAGSLGSCSEEKEDEREEEGDGDTLDSDEFCILDAPGLGIPPRDGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERSGAPPPSPPVGGPAGSLGSCSEEKEDEREEEGDGDTLDSDEFCILDAPGLGIPPRDGE
1320 1330 1340 1350 1360 1370
1380 1390 1400 1410 1420 1430
pF1KA0 PVVTQLHPGPIVVRDGYFSRPIGSTDLLRAPAHFPVPSTRVVLREVSLVWHLYGGRDFGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVVTQLHPGPIVVRDGYFSRPIGSTDLLRAPAHFPVPSTRVVLREVSLVWHLYGGRDFGP
1380 1390 1400 1410 1420 1430
1440 1450 1460 1470 1480 1490
pF1KA0 HPGHRARTGLSGPRSSPSRCSGPNRPQNSWRTQGGSGRQHHVLMEIQLSKVSFQHEVYPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HPGHRARTGLSGPRSSPSRCSGPNRPQNSWRTQGGSGRQHHVLMEIQLSKVSFQHEVYPA
1440 1450 1460 1470 1480 1490
1500 1510 1520 1530 1540 1550
pF1KA0 EPATGPAAPSQELEERPLSRQVFIVQELEVRDRLASSQINKFLYLHTSERMPRRAHSNML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EPATGPAAPSQELEERPLSRQVFIVQELEVRDRLASSQINKFLYLHTSERMPRRAHSNML
1500 1510 1520 1530 1540 1550
1560 1570 1580 1590 1600 1610
pF1KA0 TIKALHVAPTTNLGGPECCLRVSLMPLRLNVDQDALFFLKDFFTSLVAGINPVVPGETSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TIKALHVAPTTNLGGPECCLRVSLMPLRLNVDQDALFFLKDFFTSLVAGINPVVPGETSA
1560 1570 1580 1590 1600 1610
1620 1630 1640 1650 1660 1670
pF1KA0 EARPETRAQPSSPLEGQAEGVETTGSQEAPGGGHSPSPPDQQPIYFREFRFTSEVPIWLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EARPETRAQPSSPLEGQAEGVETTGSQEAPGGGHSPSPPDQQPIYFREFRFTSEVPIWLD
1620 1630 1640 1650 1660 1670
1680 1690 1700 1710 1720 1730
pF1KA0 YHGKHVTMDQVGTFAGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLGYALNEWLQDIRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YHGKHVTMDQVGTFAGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLGYALNEWLQDIRK
1680 1690 1700 1710 1720 1730
1740 1750 1760 1770 1780 1790
pF1KA0 NQLPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLMRGLQRGAASFGSSTASAAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQLPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLMRGLQRGAASFGSSTASAAL
1740 1750 1760 1770 1780 1790
1800 1810 1820 1830 1840 1850
pF1KA0 ELSNRLVQAIQATAETVYDILSPAAPVSRSLQDKRSARRLRRGQQPADLREGVAKAYDTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELSNRLVQAIQATAETVYDILSPAAPVSRSLQDKRSARRLRRGQQPADLREGVAKAYDTV
1800 1810 1820 1830 1840 1850
1860 1870 1880 1890 1900 1910
pF1KA0 REGILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVKPLILATEATSSLLGGMRNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 REGILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVKPLILATEATSSLLGGMRNQ
1860 1870 1880 1890 1900 1910
1920 1930
pF1KA0 IVPDAHKDHALKWRSDSAQD
::::::::::::::::::::
XP_005 IVPDAHKDHALKWRSDSAQD
1920 1930
>>XP_011543167 (OMIM: 616225) PREDICTED: autophagy-relat (1875 aa)
initn: 8078 init1: 8040 opt: 12621 Z-score: 10039.1 bits: 1870.9 E(85289): 0
Smith-Waterman score: 12621; 99.8% identity (99.8% similar) in 1875 aa overlap (66-1938:1-1875)
40 50 60 70 80 90
pF1KA0 DQLSLDLYKGSVALRDIHLEIWSVNEVLESMESPLELVEGFVGSIEVAVPWAALLTDHCT
::::::::::::::::::::::::::::::
XP_011 MESPLELVEGFVGSIEVAVPWAALLTDHCT
10 20 30
100 110 120 130 140 150
pF1KA0 VRVSGLQLTLQPRRGPAPGAADSQSWASCMTTSLQLAQECLRDGLPEPSEPPQPLEGLEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRVSGLQLTLQPRRGPAPGAADSQSWASCMTTSLQLAQECLRDGLPEPSEPPQPLEGLEM
40 50 60 70 80 90
160 170 180 190 200 210
pF1KA0 FAQTIETVLRRIKVTFLDTVVRVEHSPGDGERGVAVEVRVQRLEYCDEAVRDPSQAPPVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FAQTIETVLRRIKVTFLDTVVRVEHSPGDGERGVAVEVRVQRLEYCDEAVRDPSQAPPVD
100 110 120 130 140 150
220 230 240 250 260 270
pF1KA0 VHQPPAFLHKLLQLAGVRLHYEELPAQEEPPEPPLQIGSCSGYMELMVKLKQNEAFPGPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHQPPAFLHKLLQLAGVRLHYEELPAQEEPPEPPLQIGSCSGYMELMVKLKQNEAFPGPK
160 170 180 190 200 210
280 290 300 310 320 330
pF1KA0 LEVAGQLGSLHLLLTPRQLQQLQELLSAVSLTDHEGLADKLNKSRPLGAEDLWLIEQDLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEVAGQLGSLHLLLTPRQLQQLQELLSAVSLTDHEGLADKLNKSRPLGAEDLWLIEQDLN
220 230 240 250 260 270
340 350 360 370 380 390
pF1KA0 QQLQAGAVAEPLSPDPLTNPLLNLDNTDLFFSMAGLTSSVASALSELSLSDVDLASSVRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQLQAGAVAEPLSPDPLTNPLLNLDNTDLFFSMAGLTSSVASALSELSLSDVDLASSVRS
280 290 300 310 320 330
400 410 420 430 440 450
pF1KA0 DMASRRLSAQAHPAGKMAPNPLLDTMRPDSLLKMTLGGVTLTLLQTSAPSSGPPDLATHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DMASRRLSAQAHPAGKMAPNPLLDTMRPDSLLKMTLGGVTLTLLQTSAPSSGPPDLATHF
340 350 360 370 380 390
460 470 480 490 500 510
pF1KA0 FTEFDATKDGPFGSRDFHHLRPRFQRACPCSHVRLTGTAVQLSWELRTGSRGRRTTSMEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTEFDATKDGPFGSRDFHHLRPRFQRACPCSHVRLTGTAVQLSWELRTGSRGRRTTSMEV
400 410 420 430 440 450
520 530 540 550 560 570
pF1KA0 HFGQLEVLECLWPRGTSEPEYTEILTFPGTLGSQASARPCAHLRHTQILRRVPKSRPRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HFGQLEVLECLWPRGTSEPEYTEILTFPGTLGSQASARPCAHLRHTQILRRVPKSRPRRS
460 470 480 490 500 510
580 590 600 610 620 630
pF1KA0 VACHCHSELALDLANFQADVELGALDRLAALLRLATVPAEPPAGLLTEPLPAMEQQTVFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VACHCHSELALDLANFQADVELGALDRLAALLRLATVPAEPPAGLLTEPLPAMEQQTVFR
520 530 540 550 560 570
640 650 660 670 680 690
pF1KA0 LSAPRATLRLRFPIADLRPERDPWAGQAVRAEQLRLELSEPQFRSELSSGPGPPVPTHLE
:::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::
XP_011 LSAPRATLRLRFPIADLRPEPDPWAGQAVRAEQLRLELSEPQFRSELSSGPGPPVPTHLE
580 590 600 610 620 630
700 710 720 730 740 750
pF1KA0 LTCSDLHGIYEDGGKPPVPCLRVSKALDPKSTGRKYFLPQVVVTVNPQSSSTQWEVAPEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTCSDLHGIYEDGGKPPVPCLRVSKALDPKSTGRKYFLPQVVVTVNPQSSSTQWEVAPEK
640 650 660 670 680 690
760 770 780 790 800 810
pF1KA0 GEELELSVESPCELREPEPSPFSSKRTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEELELSVESPCELREPEPSPFSSKRTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEV
700 710 720 730 740 750
820 830 840 850 860 870
pF1KA0 ILPSVHIFLPSKEVYESIYNRINNDLLMWEPADLLPTPDPAAQPSGFPGPSGFWHDSFKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILPSVHIFLPSKEVYESIYNRINNDLLMWEPADLLPTPDPAAQPSGFPGPSGFWHDSFKM
760 770 780 790 800 810
880 890 900 910 920 930
pF1KA0 CKSAFKLANCFDLTPDSDSDDEDAHFFSVGASGGPQAAAPEAPSLHLQSTFSTLVTVLKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CKSAFKLANCFDLTPDSDSDDEDAHFFSVGASGGPQAAAPEAPSLHLQSTFSTLVTVLKG
820 830 840 850 860 870
940 950 960 970 980 990
pF1KA0 RITALCETKDEGGKRLEAVHGELVLDMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RITALCETKDEGGKRLEAVHGELVLDMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRA
880 890 900 910 920 930
1000 1010 1020 1030 1040 1050
pF1KA0 AVDDYPLPSHLDLPSFAPPAQLAPTIYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVDDYPLPSHLDLPSFAPPAQLAPTIYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLD
940 950 960 970 980 990
1060 1070 1080 1090 1100 1110
pF1KA0 PHKNVKEFLVTLRLHKATLRHYMALPEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHKNVKEFLVTLRLHKATLRHYMALPEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTH
1000 1010 1020 1030 1040 1050
1120 1130 1140 1150 1160 1170
pF1KA0 LFSCSVDYRPLYLPVRVLITAETFTLSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFSCSVDYRPLYLPVRVLITAETFTLSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLD
1060 1070 1080 1090 1100 1110
1180 1190 1200 1210 1220 1230
pF1KA0 LRRDYVCVLDVDLLELVIKTWKGSTEGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRRDYVCVLDVDLLELVIKTWKGSTEGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQ
1120 1130 1140 1150 1160 1170
1240 1250 1260 1270 1280 1290
pF1KA0 YVMSTGDLHPPPRPPSPTEIAGQK--LSESPASLPSCPPVETALINQRDLADALLDTERS
:::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
XP_011 YVMSTGDLHPPPRPPSPTEIAGQKVQLSESPASLPSCPPVETALINQRDLADALLDTERS
1180 1190 1200 1210 1220 1230
1300 1310 1320 1330 1340 1350
pF1KA0 LRELAQPSGGHLPQASPISVYLFPGERSGAPPPSPPVGGPAGSLGSCSEEKEDEREEEGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRELAQPSGGHLPQASPISVYLFPGERSGAPPPSPPVGGPAGSLGSCSEEKEDEREEEGD
1240 1250 1260 1270 1280 1290
1360 1370 1380 1390 1400 1410
pF1KA0 GDTLDSDEFCILDAPGLGIPPRDGEPVVTQLHPGPIVVRDGYFSRPIGSTDLLRAPAHFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDTLDSDEFCILDAPGLGIPPRDGEPVVTQLHPGPIVVRDGYFSRPIGSTDLLRAPAHFP
1300 1310 1320 1330 1340 1350
1420 1430 1440 1450 1460 1470
pF1KA0 VPSTRVVLREVSLVWHLYGGRDFGPHPGHRARTGLSGPRSSPSRCSGPNRPQNSWRTQGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPSTRVVLREVSLVWHLYGGRDFGPHPGHRARTGLSGPRSSPSRCSGPNRPQNSWRTQGG
1360 1370 1380 1390 1400 1410
1480 1490 1500 1510 1520 1530
pF1KA0 SGRQHHVLMEIQLSKVSFQHEVYPAEPATGPAAPSQELEERPLSRQVFIVQELEVRDRLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGRQHHVLMEIQLSKVSFQHEVYPAEPATGPAAPSQELEERPLSRQVFIVQELEVRDRLA
1420 1430 1440 1450 1460 1470
1540 1550 1560 1570 1580 1590
pF1KA0 SSQINKFLYLHTSERMPRRAHSNMLTIKALHVAPTTNLGGPECCLRVSLMPLRLNVDQDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSQINKFLYLHTSERMPRRAHSNMLTIKALHVAPTTNLGGPECCLRVSLMPLRLNVDQDA
1480 1490 1500 1510 1520 1530
1600 1610 1620 1630 1640 1650
pF1KA0 LFFLKDFFTSLVAGINPVVPGETSAEARPETRAQPSSPLEGQAEGVETTGSQEAPGGGHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFFLKDFFTSLVAGINPVVPGETSAEARPETRAQPSSPLEGQAEGVETTGSQEAPGGGHS
1540 1550 1560 1570 1580 1590
1660 1670 1680 1690 1700 1710
pF1KA0 PSPPDQQPIYFREFRFTSEVPIWLDYHGKHVTMDQVGTFAGLLIGLAQLNCSELKLKRLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSPPDQQPIYFREFRFTSEVPIWLDYHGKHVTMDQVGTFAGLLIGLAQLNCSELKLKRLC
1600 1610 1620 1630 1640 1650
1720 1730 1740 1750 1760 1770
pF1KA0 CRHGLLGVDKVLGYALNEWLQDIRKNQLPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRHGLLGVDKVLGYALNEWLQDIRKNQLPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYR
1660 1670 1680 1690 1700 1710
1780 1790 1800 1810 1820 1830
pF1KA0 KDGRLMRGLQRGAASFGSSTASAALELSNRLVQAIQATAETVYDILSPAAPVSRSLQDKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDGRLMRGLQRGAASFGSSTASAALELSNRLVQAIQATAETVYDILSPAAPVSRSLQDKR
1720 1730 1740 1750 1760 1770
1840 1850 1860 1870 1880 1890
pF1KA0 SARRLRRGQQPADLREGVAKAYDTVREGILDTAQTICDVASRGHEQKGLTGAVGGVIRQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SARRLRRGQQPADLREGVAKAYDTVREGILDTAQTICDVASRGHEQKGLTGAVGGVIRQL
1780 1790 1800 1810 1820 1830
1900 1910 1920 1930
pF1KA0 PPTVVKPLILATEATSSLLGGMRNQIVPDAHKDHALKWRSDSAQD
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPTVVKPLILATEATSSLLGGMRNQIVPDAHKDHALKWRSDSAQD
1840 1850 1860 1870
>>XP_011543168 (OMIM: 616225) PREDICTED: autophagy-relat (1762 aa)
initn: 8544 init1: 8506 opt: 11916 Z-score: 9478.7 bits: 1767.1 E(85289): 0
Smith-Waterman score: 11916; 99.8% identity (99.8% similar) in 1759 aa overlap (1-1757:1-1759)
10 20 30 40 50 60
pF1KA0 MSRWLWPWSNCVKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSRWLWPWSNCVKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 EVLESMESPLELVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRRGPAPGAADSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVLESMESPLELVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRRGPAPGAADSQS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 WASCMTTSLQLAQECLRDGLPEPSEPPQPLEGLEMFAQTIETVLRRIKVTFLDTVVRVEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WASCMTTSLQLAQECLRDGLPEPSEPPQPLEGLEMFAQTIETVLRRIKVTFLDTVVRVEH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 SPGDGERGVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQPPAFLHKLLQLAGVRLHYEELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPGDGERGVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQPPAFLHKLLQLAGVRLHYEELP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 AQEEPPEPPLQIGSCSGYMELMVKLKQNEAFPGPKLEVAGQLGSLHLLLTPRQLQQLQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQEEPPEPPLQIGSCSGYMELMVKLKQNEAFPGPKLEVAGQLGSLHLLLTPRQLQQLQEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LSAVSLTDHEGLADKLNKSRPLGAEDLWLIEQDLNQQLQAGAVAEPLSPDPLTNPLLNLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSAVSLTDHEGLADKLNKSRPLGAEDLWLIEQDLNQQLQAGAVAEPLSPDPLTNPLLNLD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 NTDLFFSMAGLTSSVASALSELSLSDVDLASSVRSDMASRRLSAQAHPAGKMAPNPLLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTDLFFSMAGLTSSVASALSELSLSDVDLASSVRSDMASRRLSAQAHPAGKMAPNPLLDT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 MRPDSLLKMTLGGVTLTLLQTSAPSSGPPDLATHFFTEFDATKDGPFGSRDFHHLRPRFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRPDSLLKMTLGGVTLTLLQTSAPSSGPPDLATHFFTEFDATKDGPFGSRDFHHLRPRFQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 RACPCSHVRLTGTAVQLSWELRTGSRGRRTTSMEVHFGQLEVLECLWPRGTSEPEYTEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RACPCSHVRLTGTAVQLSWELRTGSRGRRTTSMEVHFGQLEVLECLWPRGTSEPEYTEIL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 TFPGTLGSQASARPCAHLRHTQILRRVPKSRPRRSVACHCHSELALDLANFQADVELGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFPGTLGSQASARPCAHLRHTQILRRVPKSRPRRSVACHCHSELALDLANFQADVELGAL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 DRLAALLRLATVPAEPPAGLLTEPLPAMEQQTVFRLSAPRATLRLRFPIADLRPERDPWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
XP_011 DRLAALLRLATVPAEPPAGLLTEPLPAMEQQTVFRLSAPRATLRLRFPIADLRPEPDPWA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 GQAVRAEQLRLELSEPQFRSELSSGPGPPVPTHLELTCSDLHGIYEDGGKPPVPCLRVSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQAVRAEQLRLELSEPQFRSELSSGPGPPVPTHLELTCSDLHGIYEDGGKPPVPCLRVSK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 ALDPKSTGRKYFLPQVVVTVNPQSSSTQWEVAPEKGEELELSVESPCELREPEPSPFSSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALDPKSTGRKYFLPQVVVTVNPQSSSTQWEVAPEKGEELELSVESPCELREPEPSPFSSK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 RTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEVILPSVHIFLPSKEVYESIYNRINND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEVILPSVHIFLPSKEVYESIYNRINND
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 LLMWEPADLLPTPDPAAQPSGFPGPSGFWHDSFKMCKSAFKLANCFDLTPDSDSDDEDAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLMWEPADLLPTPDPAAQPSGFPGPSGFWHDSFKMCKSAFKLANCFDLTPDSDSDDEDAH
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 FFSVGASGGPQAAAPEAPSLHLQSTFSTLVTVLKGRITALCETKDEGGKRLEAVHGELVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FFSVGASGGPQAAAPEAPSLHLQSTFSTLVTVLKGRITALCETKDEGGKRLEAVHGELVL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 DMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVDDYPLPSHLDLPSFAPPAQLAPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVDDYPLPSHLDLPSFAPPAQLAPT
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 IYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLDPHKNVKEFLVTLRLHKATLRHYMAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLDPHKNVKEFLVTLRLHKATLRHYMAL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 PEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTHLFSCSVDYRPLYLPVRVLITAETFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTHLFSCSVDYRPLYLPVRVLITAETFT
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 LSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDLRRDYVCVLDVDLLELVIKTWKGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDLRRDYVCVLDVDLLELVIKTWKGST
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250
pF1KA0 EGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVMSTGDLHPPPRPPSPTEIAGQK-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVMSTGDLHPPPRPPSPTEIAGQKV
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KA0 -LSESPASLPSCPPVETALINQRDLADALLDTERSLRELAQPSGGHLPQASPISVYLFPG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLSESPASLPSCPPVETALINQRDLADALLDTERSLRELAQPSGGHLPQASPISVYLFPG
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KA0 ERSGAPPPSPPVGGPAGSLGSCSEEKEDEREEEGDGDTLDSDEFCILDAPGLGIPPRDGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERSGAPPPSPPVGGPAGSLGSCSEEKEDEREEEGDGDTLDSDEFCILDAPGLGIPPRDGE
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410 1420 1430
pF1KA0 PVVTQLHPGPIVVRDGYFSRPIGSTDLLRAPAHFPVPSTRVVLREVSLVWHLYGGRDFGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVVTQLHPGPIVVRDGYFSRPIGSTDLLRAPAHFPVPSTRVVLREVSLVWHLYGGRDFGP
1390 1400 1410 1420 1430 1440
1440 1450 1460 1470 1480 1490
pF1KA0 HPGHRARTGLSGPRSSPSRCSGPNRPQNSWRTQGGSGRQHHVLMEIQLSKVSFQHEVYPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPGHRARTGLSGPRSSPSRCSGPNRPQNSWRTQGGSGRQHHVLMEIQLSKVSFQHEVYPA
1450 1460 1470 1480 1490 1500
1500 1510 1520 1530 1540 1550
pF1KA0 EPATGPAAPSQELEERPLSRQVFIVQELEVRDRLASSQINKFLYLHTSERMPRRAHSNML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPATGPAAPSQELEERPLSRQVFIVQELEVRDRLASSQINKFLYLHTSERMPRRAHSNML
1510 1520 1530 1540 1550 1560
1560 1570 1580 1590 1600 1610
pF1KA0 TIKALHVAPTTNLGGPECCLRVSLMPLRLNVDQDALFFLKDFFTSLVAGINPVVPGETSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIKALHVAPTTNLGGPECCLRVSLMPLRLNVDQDALFFLKDFFTSLVAGINPVVPGETSA
1570 1580 1590 1600 1610 1620
1620 1630 1640 1650 1660 1670
pF1KA0 EARPETRAQPSSPLEGQAEGVETTGSQEAPGGGHSPSPPDQQPIYFREFRFTSEVPIWLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EARPETRAQPSSPLEGQAEGVETTGSQEAPGGGHSPSPPDQQPIYFREFRFTSEVPIWLD
1630 1640 1650 1660 1670 1680
1680 1690 1700 1710 1720 1730
pF1KA0 YHGKHVTMDQVGTFAGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLGYALNEWLQDIRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YHGKHVTMDQVGTFAGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLGYALNEWLQDIRK
1690 1700 1710 1720 1730 1740
1740 1750 1760 1770 1780 1790
pF1KA0 NQLPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLMRGLQRGAASFGSSTASAAL
:::::::::::::::::::
XP_011 NQLPGLLGGVGPMHSVVQLCHS
1750 1760
>>XP_011543169 (OMIM: 616225) PREDICTED: autophagy-relat (1346 aa)
initn: 8506 init1: 8506 opt: 8778 Z-score: 6984.0 bits: 1305.2 E(85289): 0
Smith-Waterman score: 8778; 98.4% identity (98.9% similar) in 1330 aa overlap (1-1323:1-1330)
10 20 30 40 50 60
pF1KA0 MSRWLWPWSNCVKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSRWLWPWSNCVKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 EVLESMESPLELVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRRGPAPGAADSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVLESMESPLELVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRRGPAPGAADSQS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 WASCMTTSLQLAQECLRDGLPEPSEPPQPLEGLEMFAQTIETVLRRIKVTFLDTVVRVEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WASCMTTSLQLAQECLRDGLPEPSEPPQPLEGLEMFAQTIETVLRRIKVTFLDTVVRVEH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 SPGDGERGVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQPPAFLHKLLQLAGVRLHYEELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPGDGERGVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQPPAFLHKLLQLAGVRLHYEELP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 AQEEPPEPPLQIGSCSGYMELMVKLKQNEAFPGPKLEVAGQLGSLHLLLTPRQLQQLQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQEEPPEPPLQIGSCSGYMELMVKLKQNEAFPGPKLEVAGQLGSLHLLLTPRQLQQLQEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 LSAVSLTDHEGLADKLNKSRPLGAEDLWLIEQDLNQQLQAGAVAEPLSPDPLTNPLLNLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSAVSLTDHEGLADKLNKSRPLGAEDLWLIEQDLNQQLQAGAVAEPLSPDPLTNPLLNLD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 NTDLFFSMAGLTSSVASALSELSLSDVDLASSVRSDMASRRLSAQAHPAGKMAPNPLLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTDLFFSMAGLTSSVASALSELSLSDVDLASSVRSDMASRRLSAQAHPAGKMAPNPLLDT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 MRPDSLLKMTLGGVTLTLLQTSAPSSGPPDLATHFFTEFDATKDGPFGSRDFHHLRPRFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRPDSLLKMTLGGVTLTLLQTSAPSSGPPDLATHFFTEFDATKDGPFGSRDFHHLRPRFQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 RACPCSHVRLTGTAVQLSWELRTGSRGRRTTSMEVHFGQLEVLECLWPRGTSEPEYTEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RACPCSHVRLTGTAVQLSWELRTGSRGRRTTSMEVHFGQLEVLECLWPRGTSEPEYTEIL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 TFPGTLGSQASARPCAHLRHTQILRRVPKSRPRRSVACHCHSELALDLANFQADVELGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFPGTLGSQASARPCAHLRHTQILRRVPKSRPRRSVACHCHSELALDLANFQADVELGAL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 DRLAALLRLATVPAEPPAGLLTEPLPAMEQQTVFRLSAPRATLRLRFPIADLRPERDPWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
XP_011 DRLAALLRLATVPAEPPAGLLTEPLPAMEQQTVFRLSAPRATLRLRFPIADLRPEPDPWA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 GQAVRAEQLRLELSEPQFRSELSSGPGPPVPTHLELTCSDLHGIYEDGGKPPVPCLRVSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQAVRAEQLRLELSEPQFRSELSSGPGPPVPTHLELTCSDLHGIYEDGGKPPVPCLRVSK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 ALDPKSTGRKYFLPQVVVTVNPQSSSTQWEVAPEKGEELELSVESPCELREPEPSPFSSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALDPKSTGRKYFLPQVVVTVNPQSSSTQWEVAPEKGEELELSVESPCELREPEPSPFSSK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 RTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEVILPSVHIFLPSKEVYESIYNRINND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEVILPSVHIFLPSKEVYESIYNRINND
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 LLMWEPADLLPTPDPAAQPSGFPGPSGFWHDSFKMCKSAFKLANCFDLTPDSDSDDEDAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLMWEPADLLPTPDPAAQPSGFPGPSGFWHDSFKMCKSAFKLANCFDLTPDSDSDDEDAH
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 FFSVGASGGPQAAAPEAPSLHLQSTFSTLVTVLKGRITALCETKDEGGKRLEAVHGELVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FFSVGASGGPQAAAPEAPSLHLQSTFSTLVTVLKGRITALCETKDEGGKRLEAVHGELVL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 DMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVDDYPLPSHLDLPSFAPPAQLAPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVDDYPLPSHLDLPSFAPPAQLAPT
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 IYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLDPHKNVKEFLVTLRLHKATLRHYMAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLDPHKNVKEFLVTLRLHKATLRHYMAL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 PEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTHLFSCSVDYRPLYLPVRVLITAETFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTHLFSCSVDYRPLYLPVRVLITAETFT
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 LSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDLRRDYVCVLDVDLLELVIKTWKGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDLRRDYVCVLDVDLLELVIKTWKGST
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250
pF1KA0 EGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVMSTGDLHPPPRPPSPTEIAGQK-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVMSTGDLHPPPRPPSPTEIAGQKV
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KA0 -LSESPASLPSCPPVETALINQRDLADALLDTERSLRELAQPSGGHLPQ---ASPISVYL
::::::::::::::::::::::::::::::::::::::::::: .: . ..:. . :
XP_011 QLSESPASLPSCPPVETALINQRDLADALLDTERSLRELAQPSGQELASQVPGAPLPAAL
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KA0 FP-GERS-GAPPPSPPVGGPAGSLGSCSEEKEDEREEEGDGDTLDSDEFCILDAPGLGIP
: : :. ::
XP_011 APTGPRTHGARRGAAGGSTMSSWRSS
1330 1340
>>XP_011543170 (OMIM: 616225) PREDICTED: autophagy-relat (1152 aa)
initn: 4600 init1: 4600 opt: 7780 Z-score: 6191.1 bits: 1158.2 E(85289): 0
Smith-Waterman score: 7780; 99.8% identity (99.8% similar) in 1152 aa overlap (789-1938:1-1152)
760 770 780 790 800 810
pF1KA0 LELSVESPCELREPEPSPFSSKRTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEVILP
::::::::::::::::::::::::::::::
XP_011 MVIPGDPEEMRTFQSRTLALSRCSLEVILP
10 20 30
820 830 840 850 860 870
pF1KA0 SVHIFLPSKEVYESIYNRINNDLLMWEPADLLPTPDPAAQPSGFPGPSGFWHDSFKMCKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVHIFLPSKEVYESIYNRINNDLLMWEPADLLPTPDPAAQPSGFPGPSGFWHDSFKMCKS
40 50 60 70 80 90
880 890 900 910 920 930
pF1KA0 AFKLANCFDLTPDSDSDDEDAHFFSVGASGGPQAAAPEAPSLHLQSTFSTLVTVLKGRIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFKLANCFDLTPDSDSDDEDAHFFSVGASGGPQAAAPEAPSLHLQSTFSTLVTVLKGRIT
100 110 120 130 140 150
940 950 960 970 980 990
pF1KA0 ALCETKDEGGKRLEAVHGELVLDMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALCETKDEGGKRLEAVHGELVLDMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVD
160 170 180 190 200 210
1000 1010 1020 1030 1040 1050
pF1KA0 DYPLPSHLDLPSFAPPAQLAPTIYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLDPHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DYPLPSHLDLPSFAPPAQLAPTIYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLDPHK
220 230 240 250 260 270
1060 1070 1080 1090 1100 1110
pF1KA0 NVKEFLVTLRLHKATLRHYMALPEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTHLFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVKEFLVTLRLHKATLRHYMALPEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTHLFS
280 290 300 310 320 330
1120 1130 1140 1150 1160 1170
pF1KA0 CSVDYRPLYLPVRVLITAETFTLSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSVDYRPLYLPVRVLITAETFTLSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDLRR
340 350 360 370 380 390
1180 1190 1200 1210 1220 1230
pF1KA0 DYVCVLDVDLLELVIKTWKGSTEGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DYVCVLDVDLLELVIKTWKGSTEGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVM
400 410 420 430 440 450
1240 1250 1260 1270 1280 1290
pF1KA0 STGDLHPPPRPPSPTEIAGQK--LSESPASLPSCPPVETALINQRDLADALLDTERSLRE
::::::::::::::::::::: :::::::::::::::::::::::::::::::::::::
XP_011 STGDLHPPPRPPSPTEIAGQKVQLSESPASLPSCPPVETALINQRDLADALLDTERSLRE
460 470 480 490 500 510
1300 1310 1320 1330 1340 1350
pF1KA0 LAQPSGGHLPQASPISVYLFPGERSGAPPPSPPVGGPAGSLGSCSEEKEDEREEEGDGDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAQPSGGHLPQASPISVYLFPGERSGAPPPSPPVGGPAGSLGSCSEEKEDEREEEGDGDT
520 530 540 550 560 570
1360 1370 1380 1390 1400 1410
pF1KA0 LDSDEFCILDAPGLGIPPRDGEPVVTQLHPGPIVVRDGYFSRPIGSTDLLRAPAHFPVPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDSDEFCILDAPGLGIPPRDGEPVVTQLHPGPIVVRDGYFSRPIGSTDLLRAPAHFPVPS
580 590 600 610 620 630
1420 1430 1440 1450 1460 1470
pF1KA0 TRVVLREVSLVWHLYGGRDFGPHPGHRARTGLSGPRSSPSRCSGPNRPQNSWRTQGGSGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRVVLREVSLVWHLYGGRDFGPHPGHRARTGLSGPRSSPSRCSGPNRPQNSWRTQGGSGR
640 650 660 670 680 690
1480 1490 1500 1510 1520 1530
pF1KA0 QHHVLMEIQLSKVSFQHEVYPAEPATGPAAPSQELEERPLSRQVFIVQELEVRDRLASSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHHVLMEIQLSKVSFQHEVYPAEPATGPAAPSQELEERPLSRQVFIVQELEVRDRLASSQ
700 710 720 730 740 750
1540 1550 1560 1570 1580 1590
pF1KA0 INKFLYLHTSERMPRRAHSNMLTIKALHVAPTTNLGGPECCLRVSLMPLRLNVDQDALFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 INKFLYLHTSERMPRRAHSNMLTIKALHVAPTTNLGGPECCLRVSLMPLRLNVDQDALFF
760 770 780 790 800 810
1600 1610 1620 1630 1640 1650
pF1KA0 LKDFFTSLVAGINPVVPGETSAEARPETRAQPSSPLEGQAEGVETTGSQEAPGGGHSPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKDFFTSLVAGINPVVPGETSAEARPETRAQPSSPLEGQAEGVETTGSQEAPGGGHSPSP
820 830 840 850 860 870
1660 1670 1680 1690 1700 1710
pF1KA0 PDQQPIYFREFRFTSEVPIWLDYHGKHVTMDQVGTFAGLLIGLAQLNCSELKLKRLCCRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDQQPIYFREFRFTSEVPIWLDYHGKHVTMDQVGTFAGLLIGLAQLNCSELKLKRLCCRH
880 890 900 910 920 930
1720 1730 1740 1750 1760 1770
pF1KA0 GLLGVDKVLGYALNEWLQDIRKNQLPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLLGVDKVLGYALNEWLQDIRKNQLPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDG
940 950 960 970 980 990
1780 1790 1800 1810 1820 1830
pF1KA0 RLMRGLQRGAASFGSSTASAALELSNRLVQAIQATAETVYDILSPAAPVSRSLQDKRSAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLMRGLQRGAASFGSSTASAALELSNRLVQAIQATAETVYDILSPAAPVSRSLQDKRSAR
1000 1010 1020 1030 1040 1050
1840 1850 1860 1870 1880 1890
pF1KA0 RLRRGQQPADLREGVAKAYDTVREGILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLRRGQQPADLREGVAKAYDTVREGILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPT
1060 1070 1080 1090 1100 1110
1900 1910 1920 1930
pF1KA0 VVKPLILATEATSSLLGGMRNQIVPDAHKDHALKWRSDSAQD
::::::::::::::::::::::::::::::::::::::::::
XP_011 VVKPLILATEATSSLLGGMRNQIVPDAHKDHALKWRSDSAQD
1120 1130 1140 1150
>>NP_060506 (OMIM: 616226) autophagy-related protein 2 h (2078 aa)
initn: 4375 init1: 951 opt: 2276 Z-score: 1809.1 bits: 348.3 E(85289): 5e-94
Smith-Waterman score: 4658; 42.6% identity (67.4% similar) in 2022 aa overlap (98-1932:95-2074)
70 80 90 100 110 120
pF1KA0 SPLELVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRRGPAPGAADSQSWASCMTT
: ::.....:: :: :. . . :.: ::.
NP_060 APLEVTEGFIQSISLSVPWGSLLQDNCALEVRGLEMVFRPRPRPATGS-EPMYWSSFMTS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 SLQLAQECLRDGLP-EPSEPPQPLEGLEMFAQTIETVLRRIKVTFLDTVVRVEHSPGDGE
:.:::.::: . : : .: ::.:::: ::.::::::::.::::.:::.:.:: : ...
NP_060 SMQLAKECLSQKLTDEQGEGSQPFEGLEKFAETIETVLRRVKVTFIDTVLRIEHVPENSK
130 140 150 160 170 180
190 200 210 220 230
pF1KA0 RGVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQPPAFLHKLLQLAGVRLHYEEL-------
:.:.:.:..: ::::.. : :.. ..:::: :: ::::::.:: : ..:.
NP_060 TGTALEIRIERTVYCDETA-DESSG--INVHQPTAFAHKLLQLSGVSLFWDEFSASAKSS
190 200 210 220 230 240
240 250 260
pF1KA0 ------PAQEEP-------------PEP-------------PLQIGSCSGYMELMVKLKQ
:.. :: :.: :.::: : .:: . :::
NP_060 PVCSTAPVETEPKLSPSWNPKIIYEPHPQLTRNLPEIAPSDPVQIGRLIGRLELSLTLKQ
250 260 270 280 290 300
270 280 290 300 310 320
pF1KA0 NEAFPGPKLEVAGQLGSLHLLLTPRQLQQLQELLSAVSLTDHE---GLADKLNKSRPLGA
::..:: ::.: ::. :.::::.:::.. : ..:.:.. .. :::.: :.::.
NP_060 NEVLPGAKLDVDGQIDSIHLLLSPRQVHLLLDMLAAIAGPENSSKIGLANKDRKNRPMQQ
310 320 330 340 350 360
330 340 350 360 370
pF1KA0 EDLWLIEQDLNQ------QLQAGAVAEPLSPDPLTNPLLNLDNTDLFFSMAGLTSSVASA
:: . :...::. .:..:. .: . : . . ..::::: . ... .
NP_060 EDEYRIQMELNRYYLRKDSLSVGVSSEQSFYETETARTPSSREEEVFFSMADM--DMSHS
370 380 390 400 410
380 390 400
pF1KA0 LSELS-LSD---VDLASSVRSDM----ASRRLSAQA----------H-----------PA
:: : :.: .:: :. : . :. ::: . : :.
NP_060 LSSLPPLGDPPNMDLELSLTSTYTNTPAGSPLSATVLQPTWGEFLDHHKEQPVRGSTFPS
420 430 440 450 460 470
410 420 430 440 450
pF1KA0 GKMAPNPL-----------LDTMRPDSLLKMTLGGVTLTLLQTSAPSSGPPD--------
. . :.:: .: ::. ......: ....:. . : : ::.
NP_060 NLVHPTPLQKTSLPSRSVSVDESRPELIFRLAVGTFSISVLHID-PLS-PPETSQNLNPL
480 490 500 510 520 530
460 470 480 490 500
pF1KA0 --LATHFFTEFDATKDGPFGSRDFHHLRPRFQRACPCSHVRLTGTAVQLSWELRTGSRGR
.:. ::: .. . :...::. .: : .:: .:.:. ::....:.: : : .
NP_060 TPMAVAFFTCIEKIDPARFSTEDFKSFRAVFAEACSHDHLRFIGTGIKVSYEQRQRS-AS
540 550 560 570 580 590
510 520 530 540 550 560
pF1KA0 RTTSMEVHFGQLEVLECLWPRG--TSEPEYTEILTFPGTLGSQASARPCAHLRHTQILRR
: : .. .::.: ::::.: . :.:::.::: . . . . : .:.. . :
NP_060 RYFSTDMSIGQMEFLECLFPTDFHSVPPHYTELLTFHSKEETGSHSPVCLQLHYKHSENR
600 610 620 630 640 650
570 580 590 600 610
pF1KA0 VPKSRPRRSVACHCHSELALDLANFQADVELGALDRLAALL---RLATVPA---------
:.. : . ..:: . : ..... .::: .:: .::::
NP_060 GPQGNQARLSSVPHKAELQIKLNPVCCELDISIVDRLNSLLQPQKLATVEMMASHMYTSY
660 670 680 690 700 710
620 630 640 650 660
pF1KA0 EPPAGL---LTEPL------PAMEQQTVFRLSAPRATLRLRFPIADLRP--ERDPWAGQA
. .: .:: . :: . .: ....: .: .:::: ::: :: :: ..
NP_060 NKHISLHKAFTEVFLDDSHSPANCRISV-QVATPALNLSVRFPIPDLRSDQERGPWFKKS
720 730 740 750 760 770
670 680 690 700 710 720
pF1KA0 VRAEQLRLELSEPQFRSELSSGPGPPVPTHLELTCSDLHGIY-EDGGKPPVPCLRVSKAL
.. : : : ... .:..:. .: . : .:::: .: : . :. : : . ..::...
NP_060 LQKEILYLAFTDLEFKTEFIGG-STPEQIKLELTFRELIGSFQEEKGDPSIKFFHVSSGV
780 790 800 810 820 830
730 740 750 760
pF1KA0 DPKSTGRKYF-LPQVVVTVNPQSSSTQWE-VAPEKGEELE-----------LSVESPCEL
: .:. : :..:. .:: . . : .: :. :: . :... :.:
NP_060 DGDTTSSDDFDWPRIVLKINPPAMHSILERIAAEEEEENDGHYQEEEEGGAHSLKDVCDL
840 850 860 870 880 890
770 780 790 800 810 820
pF1KA0 REPEPSPFSSKRTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEVILPSVHIFLPSKEV
:.: ::::::.:.:.:.:.::.:::: :: ::..... :. ::. ::.... ::.:
NP_060 RRPAPSPFSSRRVMFENEQMVMPGDPVEMTEFQDKAISNSHYVLELTLPNIYVTLPNKSF
900 910 920 930 940 950
830 840 850 860 870 880
pF1KA0 YESIYNRINNDLLMWEPADLLPTP----DPAAQPSGFPGPSG----FWHDSFKMCKSAFK
::..:::: ::::.:::. :.: . . :. : : .::: ::::
NP_060 YEKLYNRIFNDLLLWEPTA--PSPVETFENISYGIGLSVASQLINTFNKDSF----SAFK
960 970 980 990 1000
890 900 910 920 930
pF1KA0 LANCFDLTPDSDSDDEDAHFFSVGASG--GPQAAAPEAPSLHLQSTFSTLVTVLKGRITA
: .: .: :..: ..::. . . . .. . . :: .:.:... .: :..
NP_060 SAVHYD--EESGSEEETLQYFSTVDPNYRSRRKKKLDSQNKNSQSFLSVLLNINHGLIAV
1010 1020 1030 1040 1050 1060
940 950 960 970 980 990
pF1KA0 LCETKDEGGKRLEAVHGELVLDMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVDD
. ..:...: :: :::. :... :.:: :..: : :.::.. . .:::.. :.
NP_060 FTDVKQDNGDLLENKHGEFWLEFNSGSLFCVTKYEGFDDKHYICLHSSSFSLYHKGIVNG
1070 1080 1090 1100 1110 1120
1000 1010 1020 1030 1040 1050
pF1KA0 YPLPSHLDLPSFAPPAQLAPTIYPSEE-GVTERGASGRKGQGRGPHMLSTAVRIHLDPHK
::.. ::: . : : :::: ::: :... ...: :.. .:::.::.: : .
NP_060 VILPTETRLPSSTRPHWLEPTIYSSEEDGLSKTSSDGVGGDSL--NMLSVAVKILSDKSE
1130 1140 1150 1160 1170 1180
1060 1070 1080 1090 1100 1110
pF1KA0 -NVKEFLVTLRLHKATLRHYMALPEQ-SWHSQLLEFLDVLDDPVLGYLPPTVITILHTHL
:.::::... :. :::.: : :: ::: :.: ::.. :.::::: ::: .: .:.::
NP_060 SNTKEFLIAVGLKGATLQHRM-LPSGLSWHEQILYFLNIADEPVLGYNPPTSFTTFHVHL
1190 1200 1210 1220 1230 1240
1120 1130 1140 1150 1160 1170
pF1KA0 FSCSVDYRPLYLPVRVLITAETFTLSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDL
.::..::::::::.: :.:.:::..::.. .: :. ::.:::..::.:::::.. :..:
NP_060 WSCALDYRPLYLPIRSLLTVETFSVSSSVALDKSSSTLRIILDEAALHLSDKCNTVTINL
1250 1260 1270 1280 1290 1300
1180 1190 1200 1210 1220 1230
pF1KA0 RRDYVCVLDVDLLELVIKTWKGSTEGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQY
:::: :.:. ::::.: . :....:. ..: :::.::..:::...:.:::: :.::.::
NP_060 SRDYVRVMDMGLLELTITAVKSDSDGEQTEPRFELHCSSDVVHIRTCSDSCAALMNLIQY
1310 1320 1330 1340 1350 1360
1240 1250 1260 1270 1280 1290
pF1KA0 VMSTGDLHPPPRPP-SPTEIAGQKLSESPASLPSCPPVETALINQ--RDL-ADAL--LDT
. : :::. : . .: . .. .: . : :: .: ::: .::. .:
NP_060 IASYGDLQTPNKADMKPGAFQRRSKVDSSGRSSSRGPVLPEADQQMLRDLMSDAMEEIDM
1370 1380 1390 1400 1410 1420
1300 1310 1320 1330 1340
pF1KA0 ERSLRELAQPSGGHLPQASPIS------VYLFPGERSGAPPPSPPVGGPAGSLGSCSEEK
... . ..: : . : :. ..::: : ... : : . .: :..
NP_060 QQGTSSVKPQANGVLDEKSQIQEPCCSDLFLFPDESGNVSQESGP------TYASFSHHF
1430 1440 1450 1460 1470
1350 1360 1370 1380 1390 1400
pF1KA0 EDEREEEGDGDTLDSDEFCILDAPGLGIPPRDGEPVVTQLHPGPIVVRDGYFSRPIGSTD
.. : ..:.:::: :: .. .. :::. . ::.::.::: :...::
NP_060 ISDAMT---GVPTENDDFCILFAPKAAMQEKEEEPVIKIMVDDAIVIRDNYFSLPVNKTD
1480 1490 1500 1510 1520 1530
1410 1420 1430 1440 1450 1460
pF1KA0 LLRAPAHFPVPSTRVVLREVSLVWHLYGGRDFGPHPGHRARTGLSGPRSSPSRCSGPNRP
.:: :::.: : :..:::::::::::.::: : . .:.::::. :.:
NP_060 TSKAPLHFPIPVIRYVVKEVSLVWHLYGGKDFGTVPPTSPAKSYISPHSSPSHT--PTR-
1540 1550 1560 1570 1580 1590
1470 1480 1490 1500 1510 1520
pF1KA0 QNSWRTQGGSGRQHHVLMEIQLSKVSFQHEVYPAEPATGPAAPSQELEERPLSRQVFIVQ
.. . ::.::.: :::::::::.::::::: : : :. : :.:.::::::::
NP_060 HGRNTVCGGKGRNHDFLMEIQLSKVKFQHEVYP--PCK-PDCDSS-LSEHPVSRQVFIVQ
1600 1610 1620 1630 1640
1530 1540 1550 1560 1570 1580
pF1KA0 ELEVRDRLASSQINKFLYLHTSERMPRRAHSNMLTIKALHVAPTTNLGGPECCLRVSLMP
.::.:::::.::.::::::. :..:::.:::::::.::::: : .. . ::::::::::
NP_060 DLEIRDRLATSQMNKFLYLYCSKEMPRKAHSNMLTVKALHVCPESGRSPQECCLRVSLMP
1650 1660 1670 1680 1690 1700
1590 1600 1610 1620
pF1KA0 LRLNVDQDALFFLKDFFTSLVAGI------NPVV---PGETSAEARPE---TRAQP----
::::.::::::::::::::: : . .: : :: . . :. : .:
NP_060 LRLNIDQDALFFLKDFFTSLSAEVELQMTPDPEVKKSPGADVTCSLPRHLSTSKEPNLVI
1710 1720 1730 1740 1750 1760
1630 1640 1650 1660 1670 1680
pF1KA0 --SSPLE----GQAEGVETTGSQEAPGGGHSPSPPDQQPIYFREFRFTSEVPIWLDYHGK
:.: . .:..::.....: . . . .::..:::::::::::: ::::::
NP_060 SFSGPKQPSQNDSANSVEVVNGMEEKNFSAEEASFRDQPVFFREFRFTSEVPIRLDYHGK
1770 1780 1790 1800 1810 1820
1690 1700 1710 1720 1730 1740
pF1KA0 HVTMDQVGTFAGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLGYALNEWLQDIRKNQLP
::.::: ::.::.::::::::::::::::: :::::::::...::..:::.::.:::::
NP_060 HVSMDQ-GTLAGILIGLAQLNCSELKLKRLSYRHGLLGVDKLFSYAITEWLNDIKKNQLP
1830 1840 1850 1860 1870 1880
1750 1760 1770 1780 1790 1800
pF1KA0 GLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLMRGLQRGAASFGSSTASAALELSN
:.:::::::::.::: ::..::.::::::::::::..::.::::::::.::: :::::.:
NP_060 GILGGVGPMHSLVQLVQGLKDLVWLPIEQYRKDGRIVRGFQRGAASFGTSTAMAALELTN
1890 1900 1910 1920 1930 1940
1810 1820 1830 1840 1850 1860
pF1KA0 RLVQAIQATAETVYDILSPAAPVSRSLQDKRSAR--RLRRGQQPADLREGVAKAYDTVRE
:.::.:::.:::.::..::. . :.. :.. : . : ..::.::::::::::..:.:
NP_060 RMVQTIQAAAETAYDMVSPG---TLSIEPKKTKRFPHHRLAHQPVDLREGVAKAYSVVKE
1950 1960 1970 1980 1990 2000
1870 1880 1890 1900 1910 1920
pF1KA0 GILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVKPLILATEATSSLLGGMRNQIV
:: :::::: ..:.: ::..:.::::: :.::.::.::::::.::::::..::::::::
NP_060 GITDTAQTIYETAAREHESRGVTGAVGEVLRQIPPAVVKPLIVATEATSNVLGGMRNQIR
2010 2020 2030 2040 2050 2060
1930
pF1KA0 PDAHKDHALKWRSDSAQD
::...:.. :::
NP_060 PDVRQDESQKWRHGDD
2070
>--
initn: 419 init1: 388 opt: 388 Z-score: 307.2 bits: 70.4 E(85289): 2.3e-10
Smith-Waterman score: 388; 56.0% identity (89.0% similar) in 91 aa overlap (6-96:3-93)
10 20 30 40 50 60
pF1KA0 MSRWLWPWSNCVKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVN
::.:. .:.:.:::::..:::::.::.:::.:::::::.:. .: .. :. : .:
NP_060 MPWPFSESIKKRACRYLLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLN
10 20 30 40 50
70 80 90 100 110 120
pF1KA0 EVLESMESPLELVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRRGPAPGAADSQS
:.::: ..:::..:::. :: ..:::..:: :.:..
NP_060 EILESADAPLEVTEGFIQSISLSVPWGSLLQDNCALEVRGLEMVFRPRPRPATGSEPMYW
60 70 80 90 100 110
130 140 150 160 170 180
pF1KA0 WASCMTTSLQLAQECLRDGLPEPSEPPQPLEGLEMFAQTIETVLRRIKVTFLDTVVRVEH
NP_060 SSFMTSSMQLAKECLSQKLTDEQGEGSQPFEGLEKFAETIETVLRRVKVTFIDTVLRIEH
120 130 140 150 160 170
1938 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 18:48:17 2016 done: Wed Nov 2 18:48:19 2016
Total Scan time: 17.090 Total Display time: 1.130
Function used was FASTA [36.3.4 Apr, 2011]