Result of FASTA (ccds) for
pF1KA0351
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0351, 557 aa
1>>>pF1KA0351 557 - 557 aa - 557 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.0528+/-0.000946; mu= 10.4691+/- 0.057
mean_var=107.7833+/-21.226, 0's: 0 Z-trim(108.4): 67 B-trim: 0 in 0/50
Lambda= 0.123537
statistics sampled from 10149 (10216) to 10149 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.687), E-opt: 0.2 (0.314), width: 16
Scan time: 3.010
The best scores are: opt bits E(32554)
CCDS35143.1 RALGPS1 gene_id:9649|Hs108|chr9 ( 557) 3650 661.5 7.7e-190
CCDS65733.1 RALGPS2 gene_id:55103|Hs108|chr1 ( 557) 2324 425.1 1.1e-118
CCDS55346.1 RALGPS1 gene_id:9649|Hs108|chr9 ( 529) 2232 408.7 8.8e-114
CCDS55345.1 RALGPS1 gene_id:9649|Hs108|chr9 ( 537) 2232 408.7 8.9e-114
CCDS55344.1 RALGPS1 gene_id:9649|Hs108|chr9 ( 305) 1928 354.4 1.1e-97
CCDS1325.1 RALGPS2 gene_id:55103|Hs108|chr1 ( 583) 1758 324.3 2.6e-88
CCDS4052.1 RASGRF2 gene_id:5924|Hs108|chr5 (1237) 412 84.5 8.1e-16
CCDS42065.1 RASGRF1 gene_id:5923|Hs108|chr15 ( 489) 396 81.5 2.6e-15
CCDS1802.1 SOS1 gene_id:6654|Hs108|chr2 (1333) 400 82.4 3.8e-15
CCDS45320.1 RASGRF1 gene_id:5923|Hs108|chr15 (1257) 396 81.7 6e-15
CCDS10309.1 RASGRF1 gene_id:5923|Hs108|chr15 (1273) 396 81.7 6e-15
CCDS9697.1 SOS2 gene_id:6655|Hs108|chr14 (1332) 362 75.6 4.2e-13
CCDS48047.1 RAPGEF1 gene_id:2889|Hs108|chr9 (1077) 323 68.6 4.3e-11
CCDS78450.1 RAPGEF1 gene_id:2889|Hs108|chr9 (1094) 323 68.6 4.4e-11
CCDS48048.1 RAPGEF1 gene_id:2889|Hs108|chr9 (1095) 323 68.6 4.4e-11
>>CCDS35143.1 RALGPS1 gene_id:9649|Hs108|chr9 (557 aa)
initn: 3650 init1: 3650 opt: 3650 Z-score: 3521.7 bits: 661.5 E(32554): 7.7e-190
Smith-Waterman score: 3650; 100.0% identity (100.0% similar) in 557 aa overlap (1-557:1-557)
10 20 30 40 50 60
pF1KA0 MYKRNGLMASVLVTSATPQGSSSSDSLEGQSCDYASKSYDAVVFDVLKVTPEEFASQITL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 MYKRNGLMASVLVTSATPQGSSSSDSLEGQSCDYASKSYDAVVFDVLKVTPEEFASQITL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 MDIPVFKAIQPEELASCGWSKKEKHSLAPNVVAFTRRFNQVSFWVVREILTAQTLKIRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 MDIPVFKAIQPEELASCGWSKKEKHSLAPNVVAFTRRFNQVSFWVVREILTAQTLKIRAE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 ILSHFVKIAKKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKTTFEKLDYLMSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 ILSHFVKIAKKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKTTFEKLDYLMSK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 EDNYKRTREYIRSLKMVPSIPYLGIYLLDLIYIDSAYPASGSIMENEQRSNQMNNILRII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 EDNYKRTREYIRSLKMVPSIPYLGIYLLDLIYIDSAYPASGSIMENEQRSNQMNNILRII
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ADLQVSCSYDHLTTLPHVQKYLKSVRYIEELQKFVEDDNYKLSLRIEPGSSSPRLVSSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 ADLQVSCSYDHLTTLPHVQKYLKSVRYIEELQKFVEDDNYKLSLRIEPGSSSPRLVSSKE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 DLAGPSAGSGSARFSRRPTCPDTSVAGSLPTPPVPRHRKSHSLGNNMMCQLSVVESKSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 DLAGPSAGSGSARFSRRPTCPDTSVAGSLPTPPVPRHRKSHSLGNNMMCQLSVVESKSAT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 FPSEKARHLLDDSVLESRSPRRGLALTSSSAVTNGLSLGSSESSEFSEEMSSGLESPTGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 FPSEKARHLLDDSVLESRSPRRGLALTSSSAVTNGLSLGSSESSEFSEEMSSGLESPTGP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 CICSLGNSAAVPTMEGPLRRKTLLKEGRKPALSSWTRYWVILSGSTLLYYGAKSLRGTDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 CICSLGNSAAVPTMEGPLRRKTLLKEGRKPALSSWTRYWVILSGSTLLYYGAKSLRGTDR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 KHYKSTPGKKVSIVGWMVQLPDDPEHPDIFQLNNPDKGNVYKFQTGSRFHAILWHKHLDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 KHYKSTPGKKVSIVGWMVQLPDDPEHPDIFQLNNPDKGNVYKFQTGSRFHAILWHKHLDD
490 500 510 520 530 540
550
pF1KA0 ACKSNRPQVPANLMSFE
:::::::::::::::::
CCDS35 ACKSNRPQVPANLMSFE
550
>>CCDS65733.1 RALGPS2 gene_id:55103|Hs108|chr1 (557 aa)
initn: 2249 init1: 1189 opt: 2324 Z-score: 2244.5 bits: 425.1 E(32554): 1.1e-118
Smith-Waterman score: 2324; 64.0% identity (85.0% similar) in 561 aa overlap (5-557:5-557)
10 20 30 40 50 60
pF1KA0 MYKRNGLMASVLVTSATPQGSSSSDSLEGQSCDYASKSYDAVVFDVLKVTPEEFASQITL
:: .:: ..... . ::::.:: .. . .::.::::::::::::::.:.::::
CCDS65 MDLMNGQASSVNIAATASEKSSSSESLSDKGSEL-KKSFDAVVFDVLKVTPEEYAGQITL
10 20 30 40 50
70 80 90 100 110 120
pF1KA0 MDIPVFKAIQPEELASCGWSKKEKHSLAPNVVAFTRRFNQVSFWVVREILTAQTLKIRAE
::.::::::::.::.::::.::::.: :::.::::::::.:::::::::: :::::::::
CCDS65 MDVPVFKAIQPDELSSCGWNKKEKYSSAPNAVAFTRRFNHVSFWVVREILHAQTLKIRAE
60 70 80 90 100 110
130 140 150 160 170 180
pF1KA0 ILSHFVKIAKKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKTTFEKLDYLMSK
.:::..: :::: ::::::.::.:::.::::::::::::::::.::::::::::.:.:::
CCDS65 VLSHYIKTAKKLYELNNLHALMAVVSGLQSAPIFRLTKTWALLSRKDKTTFEKLEYVMSK
120 130 140 150 160 170
190 200 210 220 230 240
pF1KA0 EDNYKRTREYIRSLKMVPSIPYLGIYLLDLIYIDSAYPASGSIMENEQRSNQMNNILRII
:::::: :.:: ::::.: :::::::: :: :::::::..:::.::::::: ::::::::
CCDS65 EDNYKRLRDYISSLKMTPCIPYLGIYLSDLTYIDSAYPSTGSILENEQRSNLMNNILRII
180 190 200 210 220 230
250 260 270 280 290 300
pF1KA0 ADLQVSCSYDHLTTLPHVQKYLKSVRYIEELQKFVEDDNYKLSLRIEPGSSSPRLVSSKE
.::: :: :: . ::::::::.::.::::::::::::::::::.::::.:.:: ..:.:
CCDS65 SDLQQSCEYD-IPMLPHVQKYLNSVQYIEELQKFVEDDNYKLSLKIEPGTSTPRSAASRE
240 250 260 270 280 290
310 320 330 340 350
pF1KA0 DLAGPSAGSGSARFSRRPTCPDTSVAGSLP-TPPVPR------HRKSHSLGNNMMCQLSV
::.:: .:. : . .:. . . .. :: ::: :: ::: :::: :.. ....
CCDS65 DLVGPEVGA-SPQSGRKSVAAEGAL---LPQTPPSPRNLIPHGHRKCHSLGYNFIHKMNT
300 310 320 330 340 350
360 370 380 390 400 410
pF1KA0 VESKSATFPSEKARHLLDDSVLESRSPRRGLALTSSSAVTNGLSLGSSESSEFSEEMS-S
.: ::::::. ::::::::.: ..: :: : ::....:.:.:::..::.::: :
CCDS65 AEFKSATFPNAGPRHLLDDSVMEPHAPSRGQA--ESSTLSSGISIGSSDGSELSEETSWP
360 370 380 390 400 410
420 430 440 450 460 470
pF1KA0 GLESPTGPCICSLGNSAAVPTMEGPLRRKTLLKEGRKPALSSWTRYWVILSGSTLLYYGA
..:: . .. .. :..: ::::::::::.::...:::.::. : :. :.::.:
CCDS65 AFESSAESEDLAVHLYPGAVTIQGVLRRKTLLKEGKKPTVASWTKYWAALCGTQLFYYAA
420 430 440 450 460 470
480 490 500 510 520 530
pF1KA0 KSLRGTDRKHYKSTPGKKVSIVGWMVQLPDDPEHPDIFQLNNPDKGNVYKFQTGSRFHAI
:::..:.:::.::: .:.::..::::.. :::::::.: :.. .::: ::::.:.:..:.
CCDS65 KSLKATERKHFKSTSNKNVSVIGWMVMMADDPEHPDLFLLTDSEKGNSYKFQAGNRMNAM
480 490 500 510 520 530
540 550
pF1KA0 LWHKHLDDACKSNRPQVPANLMSFE
:: :::. ::.::. :::.:::.::
CCDS65 LWFKHLSAACQSNKQQVPTNLMTFE
540 550
>>CCDS55346.1 RALGPS1 gene_id:9649|Hs108|chr9 (529 aa)
initn: 2678 init1: 2232 opt: 2232 Z-score: 2156.3 bits: 408.7 E(32554): 8.8e-114
Smith-Waterman score: 2998; 87.2% identity (88.7% similar) in 548 aa overlap (1-548:1-498)
10 20 30 40 50 60
pF1KA0 MYKRNGLMASVLVTSATPQGSSSSDSLEGQSCDYASKSYDAVVFDVLKVTPEEFASQITL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 MYKRNGLMASVLVTSATPQGSSSSDSLEGQSCDYASKSYDAVVFDVLKVTPEEFASQITL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 MDIPVFKAIQPEELASCGWSKKEKHSLAPNVVAFTRRFNQVSFWVVREILTAQTLKIRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 MDIPVFKAIQPEELASCGWSKKEKHSLAPNVVAFTRRFNQVSFWVVREILTAQTLKIRAE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 ILSHFVKIAKKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKTTFEKLDYLMSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 ILSHFVKIAKKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKTTFEKLDYLMSK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 EDNYKRTREYIRSLKMVPSIPYLGIYLLDLIYIDSAYPASGSIMENEQRSNQMNNILRII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 EDNYKRTREYIRSLKMVPSIPYLGIYLLDLIYIDSAYPASGSIMENEQRSNQMNNILRII
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ADLQVSCSYDHLTTLPHVQKYLKSVRYIEELQKFVEDDNYKLSLRIEPGSSSPRLVSSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 ADLQVSCSYDHLTTLPHVQKYLKSVRYIEELQKFVEDDNYKLSLRIEPGSSSPRLVSSKE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 DLAGPSAGSGSARFSRRPTCPDTSVAGSLPTPPVPRHRKSHSLGNNMMCQLSVVESKSAT
:::::::::::::::::::::::::::::::::::::::::::::: .: .. . .
CCDS55 DLAGPSAGSGSARFSRRPTCPDTSVAGSLPTPPVPRHRKSHSLGNNRG-RLYATLGPNWR
310 320 330 340 350
370 380 390 400 410 420
pF1KA0 FPSEKARHLLDDSVLESRSPRRGLALTSSSAVTNGLSLGSSESSEFSEEMSSGLESPTGP
: .:. ::: : . :::::
CCDS55 VP---VRN----------SPRT----------------------------RSCVYSPTGP
360 370
430 440 450 460 470 480
pF1KA0 CICSLGNSAAVPTMEGPLRRKTLLKEGRKPALSSWTRYWVILSGSTLLYYGAKSLRGTDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 CICSLGNSAAVPTMEGPLRRKTLLKEGRKPALSSWTRYWVILSGSTLLYYGAKSLRGTDR
380 390 400 410 420 430
490 500 510 520 530 540
pF1KA0 KHYKSTPGKKVSIVGWMVQLPDDPEHPDIFQLNNPDKGNVYKFQTGSRFHAILWHKHLDD
:: ::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 KH--------VSIVGWMVQLPDDPEHPDIFQLNNPDKGNVYKFQTGSRFHAILWHKHLDD
440 450 460 470 480 490
550
pF1KA0 ACKSNRPQVPANLMSFE
::::::::
CCDS55 ACKSNRPQEAGAAPGPTGTDSHEVDHLEGGAGKEAGPCA
500 510 520
>>CCDS55345.1 RALGPS1 gene_id:9649|Hs108|chr9 (537 aa)
initn: 3161 init1: 2232 opt: 2232 Z-score: 2156.2 bits: 408.7 E(32554): 8.9e-114
Smith-Waterman score: 3078; 88.7% identity (90.1% similar) in 548 aa overlap (1-548:1-506)
10 20 30 40 50 60
pF1KA0 MYKRNGLMASVLVTSATPQGSSSSDSLEGQSCDYASKSYDAVVFDVLKVTPEEFASQITL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 MYKRNGLMASVLVTSATPQGSSSSDSLEGQSCDYASKSYDAVVFDVLKVTPEEFASQITL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 MDIPVFKAIQPEELASCGWSKKEKHSLAPNVVAFTRRFNQVSFWVVREILTAQTLKIRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 MDIPVFKAIQPEELASCGWSKKEKHSLAPNVVAFTRRFNQVSFWVVREILTAQTLKIRAE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 ILSHFVKIAKKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKTTFEKLDYLMSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 ILSHFVKIAKKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKTTFEKLDYLMSK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 EDNYKRTREYIRSLKMVPSIPYLGIYLLDLIYIDSAYPASGSIMENEQRSNQMNNILRII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 EDNYKRTREYIRSLKMVPSIPYLGIYLLDLIYIDSAYPASGSIMENEQRSNQMNNILRII
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ADLQVSCSYDHLTTLPHVQKYLKSVRYIEELQKFVEDDNYKLSLRIEPGSSSPRLVSSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 ADLQVSCSYDHLTTLPHVQKYLKSVRYIEELQKFVEDDNYKLSLRIEPGSSSPRLVSSKE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 DLAGPSAGSGSARFSRRPTCPDTSVAGSLPTPPVPRHRKSHSLGNNMMCQLSVVESKSAT
:::::::::::::::::::::::::::::::::::::::::::::: .: .. . .
CCDS55 DLAGPSAGSGSARFSRRPTCPDTSVAGSLPTPPVPRHRKSHSLGNNRG-RLYATLGPNWR
310 320 330 340 350
370 380 390 400 410 420
pF1KA0 FPSEKARHLLDDSVLESRSPRRGLALTSSSAVTNGLSLGSSESSEFSEEMSSGLESPTGP
: .:. ::: : . :::::
CCDS55 VP---VRN----------SPRT----------------------------RSCVYSPTGP
360 370
430 440 450 460 470 480
pF1KA0 CICSLGNSAAVPTMEGPLRRKTLLKEGRKPALSSWTRYWVILSGSTLLYYGAKSLRGTDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 CICSLGNSAAVPTMEGPLRRKTLLKEGRKPALSSWTRYWVILSGSTLLYYGAKSLRGTDR
380 390 400 410 420 430
490 500 510 520 530 540
pF1KA0 KHYKSTPGKKVSIVGWMVQLPDDPEHPDIFQLNNPDKGNVYKFQTGSRFHAILWHKHLDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 KHYKSTPGKKVSIVGWMVQLPDDPEHPDIFQLNNPDKGNVYKFQTGSRFHAILWHKHLDD
440 450 460 470 480 490
550
pF1KA0 ACKSNRPQVPANLMSFE
::::::::
CCDS55 ACKSNRPQEAGAAPGPTGTDSHEVDHLEGGAGKEAGPCA
500 510 520 530
>>CCDS55344.1 RALGPS1 gene_id:9649|Hs108|chr9 (305 aa)
initn: 1928 init1: 1928 opt: 1928 Z-score: 1867.2 bits: 354.4 E(32554): 1.1e-97
Smith-Waterman score: 1928; 100.0% identity (100.0% similar) in 303 aa overlap (1-303:1-303)
10 20 30 40 50 60
pF1KA0 MYKRNGLMASVLVTSATPQGSSSSDSLEGQSCDYASKSYDAVVFDVLKVTPEEFASQITL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 MYKRNGLMASVLVTSATPQGSSSSDSLEGQSCDYASKSYDAVVFDVLKVTPEEFASQITL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 MDIPVFKAIQPEELASCGWSKKEKHSLAPNVVAFTRRFNQVSFWVVREILTAQTLKIRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 MDIPVFKAIQPEELASCGWSKKEKHSLAPNVVAFTRRFNQVSFWVVREILTAQTLKIRAE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 ILSHFVKIAKKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKTTFEKLDYLMSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 ILSHFVKIAKKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKTTFEKLDYLMSK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 EDNYKRTREYIRSLKMVPSIPYLGIYLLDLIYIDSAYPASGSIMENEQRSNQMNNILRII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 EDNYKRTREYIRSLKMVPSIPYLGIYLLDLIYIDSAYPASGSIMENEQRSNQMNNILRII
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ADLQVSCSYDHLTTLPHVQKYLKSVRYIEELQKFVEDDNYKLSLRIEPGSSSPRLVSSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 ADLQVSCSYDHLTTLPHVQKYLKSVRYIEELQKFVEDDNYKLSLRIEPGSSSPRLVSSKE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 DLAGPSAGSGSARFSRRPTCPDTSVAGSLPTPPVPRHRKSHSLGNNMMCQLSVVESKSAT
:::
CCDS55 DLAAM
>>CCDS1325.1 RALGPS2 gene_id:55103|Hs108|chr1 (583 aa)
initn: 2252 init1: 1189 opt: 1758 Z-score: 1699.0 bits: 324.3 E(32554): 2.6e-88
Smith-Waterman score: 2287; 62.0% identity (81.6% similar) in 587 aa overlap (5-557:5-583)
10 20 30 40 50 60
pF1KA0 MYKRNGLMASVLVTSATPQGSSSSDSLEGQSCDYASKSYDAVVFDVLKVTPEEFASQITL
:: .:: ..... . ::::.:: .. . .::.::::::::::::::.:.::::
CCDS13 MDLMNGQASSVNIAATASEKSSSSESLSDKGSEL-KKSFDAVVFDVLKVTPEEYAGQITL
10 20 30 40 50
70 80 90 100 110 120
pF1KA0 MDIPVFKAIQPEELASCGWSKKEKHSLAPNVVAFTRRFNQVSFWVVREILTAQTLKIRAE
::.::::::::.::.::::.::::.: :::.::::::::.:::::::::: :::::::::
CCDS13 MDVPVFKAIQPDELSSCGWNKKEKYSSAPNAVAFTRRFNHVSFWVVREILHAQTLKIRAE
60 70 80 90 100 110
130 140 150 160 170 180
pF1KA0 ILSHFVKIAKKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKTTFEKLDYLMSK
.:::..: :::: ::::::.::.:::.::::::::::::::::.::::::::::.:.:::
CCDS13 VLSHYIKTAKKLYELNNLHALMAVVSGLQSAPIFRLTKTWALLSRKDKTTFEKLEYVMSK
120 130 140 150 160 170
190 200 210 220 230 240
pF1KA0 EDNYKRTREYIRSLKMVPSIPYLGIYLLDLIYIDSAYPASGSIMENEQRSNQMNNILRII
:::::: :.:: ::::.: :::::::: :: :::::::..:::.::::::: ::::::::
CCDS13 EDNYKRLRDYISSLKMTPCIPYLGIYLSDLTYIDSAYPSTGSILENEQRSNLMNNILRII
180 190 200 210 220 230
250 260 270 280 290 300
pF1KA0 ADLQVSCSYDHLTTLPHVQKYLKSVRYIEELQKFVEDDNYKLSLRIEPGSSSPRLVSSKE
.::: :: :: . ::::::::.::.::::::::::::::::::.::::.:.:: ..:.:
CCDS13 SDLQQSCEYD-IPMLPHVQKYLNSVQYIEELQKFVEDDNYKLSLKIEPGTSTPRSAASRE
240 250 260 270 280 290
310 320 330 340 350
pF1KA0 DLAGPSAGSGSARFSRRPTCPDTSVAGSLP-TPPVPR------HRKSHSLGNNMMCQLSV
::.:: .:. : . .:. . . .. :: ::: :: ::: :::: :.. ....
CCDS13 DLVGPEVGA-SPQSGRKSVAAEGAL---LPQTPPSPRNLIPHGHRKCHSLGYNFIHKMNT
300 310 320 330 340 350
360 370 380 390 400 410
pF1KA0 VESKSATFPSEKARHLLDDSVLESRSPRRGLALTSSSAVTNGLSLGSSESSEFSEEMS--
.: ::::::. ::::::::.: ..: :: : ::....:.:.:::..::.::: :
CCDS13 AEFKSATFPNAGPRHLLDDSVMEPHAPSRGQA--ESSTLSSGISIGSSDGSELSEETSWP
360 370 380 390 400 410
420 430 440
pF1KA0 ----SGLESPTGPC--ICSLG-------NSAA---------VP---TMEGPLRRKTLLKE
. : :: . : .:.: : :..: :::::::::
CCDS13 AFERNRLYHSLGPVTRVARNGYRSHMKASSSAESEDLAVHLYPGAVTIQGVLRRKTLLKE
420 430 440 450 460 470
450 460 470 480 490 500
pF1KA0 GRKPALSSWTRYWVILSGSTLLYYGAKSLRGTDRKHYKSTPGKKVSIVGWMVQLPDDPEH
:.::...:::.::. : :. :.::.::::..:.:::.::: .:.::..::::.. :::::
CCDS13 GKKPTVASWTKYWAALCGTQLFYYAAKSLKATERKHFKSTSNKNVSVIGWMVMMADDPEH
480 490 500 510 520 530
510 520 530 540 550
pF1KA0 PDIFQLNNPDKGNVYKFQTGSRFHAILWHKHLDDACKSNRPQVPANLMSFE
::.: :.. .::: ::::.:.:..:.:: :::. ::.::. :::.:::.::
CCDS13 PDLFLLTDSEKGNSYKFQAGNRMNAMLWFKHLSAACQSNKQQVPTNLMTFE
540 550 560 570 580
>>CCDS4052.1 RASGRF2 gene_id:5924|Hs108|chr5 (1237 aa)
initn: 387 init1: 268 opt: 412 Z-score: 397.4 bits: 84.5 E(32554): 8.1e-16
Smith-Waterman score: 412; 30.1% identity (62.4% similar) in 282 aa overlap (9-288:963-1233)
10 20 30
pF1KA0 MYKRNGLMASVLVTSATPQGSSSSDSLEGQSCDYASKS
:.. . : : .... :. .. .
CCDS40 FELNNELKMNVLNLLEEVLRDPDLLPQERKAAANILRALSQDDQDDIHLKLEDIIQMTDC
940 950 960 970 980 990
40 50 60 70 80 90
pF1KA0 YDAVVFDVLKVTPEEFASQITLMDIPVFKAIQPEELASCGWSKKEKHSLAPNVVAFTRRF
. : :. : . :.: ::::.: .:..: ::. . :: : .:. .: .. ...:
CCDS40 MKAECFESL--SAMELAEQITLLDHVIFRSIPYEEFLGQGWMKLDKNERTPYIMKTSQHF
1000 1010 1020 1030 1040 1050
100 110 120 130 140 150
pF1KA0 NQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLMSVVSALQSAPIFRLTK
:..: :. .:.. .. ::. . ..: .: :.: .... ..:::. . :.:: :
CCDS40 NDMSNLVASQIMNYADVSSRANAIEKWVAVADICRCLHNYNGVLEITSALNRSAIYRLKK
1060 1070 1080 1090 1100 1110
160 170 180 190 200 210
pF1KA0 TWALLNRKDKTTFEKLDYLMSKEDNYKRTREYIRSLKMVPSIPYLGIYLLDLIYIDSAYP
::: .... :. ..::. .:.: .: :: ... . :..::::.:: :: .:. . :
CCDS40 TWAKVSKQTKALMDKLQKTVSSEGRFKNLRETLKNCNP-PAVPYLGMYLTDLAFIEEGTP
1120 1130 1140 1150 1160
220 230 240 250 260 270
pF1KA0 A-SGSIMENEQRSNQMNNILRIIADLQ-VSCSYDHLTTLPHVQKYLKSVRYIEELQKFVE
. . : .. ....:.: : ..: .: :: :.: .:: . : . :
CCDS40 NFTEEGLVNFSKMRMISHIIREIRQFQQTSYRIDHQ---PKVAQYLLDKDLIID-----E
1170 1180 1190 1200 1210 1220
280 290 300 310 320 330
pF1KA0 DDNYKLSLRIEPGSSSPRLVSSKEDLAGPSAGSGSARFSRRPTCPDTSVAGSLPTPPVPR
: :.:::.:::
CCDS40 DTLYELSLKIEPRLPA
1230
>>CCDS42065.1 RASGRF1 gene_id:5923|Hs108|chr15 (489 aa)
initn: 382 init1: 287 opt: 396 Z-score: 388.3 bits: 81.5 E(32554): 2.6e-15
Smith-Waterman score: 404; 31.8% identity (64.4% similar) in 239 aa overlap (53-288:257-485)
30 40 50 60 70 80
pF1KA0 SSDSLEGQSCDYASKSYDAVVFDVLKVTPEEFASQITLMDIPVFKAIQPEELASCGWSKK
:.: :.::.: ::: : ::. . :: :
CCDS42 DPGDNQITLEEITQMAEGVKAEPFENHSALEIAEQLTLLDHLVFKKIPYEEFFGQGWMKL
230 240 250 260 270 280
90 100 110 120 130 140
pF1KA0 EKHSLAPNVVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLM
::. .: .. :..::..: .. ::. . .. :. . ..: .: :.: ....
CCDS42 EKNERTPYIMKTTKHFNDISNLIASEIIRNEDINARVSAIEKWVAVADICRCLHNYNAVL
290 300 310 320 330 340
150 160 170 180 190 200
pF1KA0 SVVSALQSAPIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKRTREYIRSLKMVPSIPY
..:... . :::: ::: .... :. ..::. :.:.: .: :: ... : .::
CCDS42 EITSSMNRSAIFRLKKTWLKVSKQTKALIDKLQKLVSSEGRFKNLREALKNCDP-PCVPY
350 360 370 380 390 400
210 220 230 240 250 260
pF1KA0 LGIYLLDLIYIDSAYPA-SGSIMENEQRSNQMNNILRIIADLQVSCSYDHLTTLPHVQKY
::.:: :: .:. . : . . . : .. ....:.: : ..: : ....
CCDS42 LGMYLTDLAFIEEGTPNYTEDGLVNFSKMRMISHIIREIRQFQ--------QTAYKIEHQ
410 420 430 440 450
270 280 290 300 310
pF1KA0 LKSVRYIEELQKFVEDDN--YKLSLRIEPGSSSPRLVSSKEDLAGPSAGSGSARFSRRPT
: ..:. . :.:: :.. :. ::::::
CCDS42 AKVTQYLLD-QSFVMDEESLYESSLRIEPKLPT
460 470 480
>>CCDS1802.1 SOS1 gene_id:6654|Hs108|chr2 (1333 aa)
initn: 360 init1: 294 opt: 400 Z-score: 385.4 bits: 82.4 E(32554): 3.8e-15
Smith-Waterman score: 400; 27.1% identity (62.0% similar) in 303 aa overlap (44-339:774-1062)
20 30 40 50 60 70
pF1KA0 TSATPQGSSSSDSLEGQSCDYASKSYDAVVFDVLKVTPEEFASQITLMDIPVFKAIQPEE
::.: . : :.: :.::.. ...:.:: :
CCDS18 RDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSE
750 760 770 780 790 800
80 90 100 110 120 130
pF1KA0 LASCGWSKKEKHSLAPNVVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLL
:.. :.:..:. .::.. . :. .....: . :. ...:. :. ..:....: . .
CCDS18 LVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQ
810 820 830 840 850 860
140 150 160 170 180 190
pF1KA0 ELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKRTREYIRS
::::..... ::::..:.:..:: .:. . ..: .:. : .::.::. .::
CCDS18 ELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHEL--SEDHYKKYLAKLRS
870 880 890 900 910 920
200 210 220 230 240
pF1KA0 LKMVPSIPYLGIYLLDLIYIDSAYPA----SGSIMENEQRSNQMNNILRIIADLQVSCSY
.. : .:..:::: ... . . : :. . : .. .. .: : . : . :
CCDS18 INP-PCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQ-NQPY
930 940 950 960 970
250 260 270 280 290 300
pF1KA0 DHLTTLPHVQKYLKSVRYI-EELQKFVEDDNYKLSLRIEPGSSSPRLVSSKEDLAGPSAG
: . ........ . . ..: : .. ::.::: . .: : . . : .
CCDS18 -CLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKP-LPRFPKKYSYPLKS
980 990 1000 1010 1020 1030
310 320 330 340 350 360
pF1KA0 SGSARFSRRPTCPDTSVAGSL--PTPPVPRHRKSHSLGNNMMCQLSVVESKSATFPSEKA
: ::. : :.. ::: . ::
CCDS18 PGV-----RPSNPRP---GTMRHPTPLQQEPRKISYSRIPESETESTASAPNSPRTPLTP
1040 1050 1060 1070 1080
370 380 390 400 410 420
pF1KA0 RHLLDDSVLESRSPRRGLALTSSSAVTNGLSLGSSESSEFSEEMSSGLESPTGPCICSLG
CCDS18 PPASGASSTTDVCSVFDSDHSSPFHSSNDTVFIQVTLPHGPRSASVSSISLTKGTDEVPV
1090 1100 1110 1120 1130 1140
>>CCDS45320.1 RASGRF1 gene_id:5923|Hs108|chr15 (1257 aa)
initn: 382 init1: 287 opt: 396 Z-score: 381.9 bits: 81.7 E(32554): 6e-15
Smith-Waterman score: 404; 31.8% identity (64.4% similar) in 239 aa overlap (53-288:1025-1253)
30 40 50 60 70 80
pF1KA0 SSDSLEGQSCDYASKSYDAVVFDVLKVTPEEFASQITLMDIPVFKAIQPEELASCGWSKK
:.: :.::.: ::: : ::. . :: :
CCDS45 DPGDNQITLEEITQMAEGVKAEPFENHSALEIAEQLTLLDHLVFKKIPYEEFFGQGWMKL
1000 1010 1020 1030 1040 1050
90 100 110 120 130 140
pF1KA0 EKHSLAPNVVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLM
::. .: .. :..::..: .. ::. . .. :. . ..: .: :.: ....
CCDS45 EKNERTPYIMKTTKHFNDISNLIASEIIRNEDINARVSAIEKWVAVADICRCLHNYNAVL
1060 1070 1080 1090 1100 1110
150 160 170 180 190 200
pF1KA0 SVVSALQSAPIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKRTREYIRSLKMVPSIPY
..:... . :::: ::: .... :. ..::. :.:.: .: :: ... : .::
CCDS45 EITSSMNRSAIFRLKKTWLKVSKQTKALIDKLQKLVSSEGRFKNLREALKNCDP-PCVPY
1120 1130 1140 1150 1160 1170
210 220 230 240 250 260
pF1KA0 LGIYLLDLIYIDSAYPA-SGSIMENEQRSNQMNNILRIIADLQVSCSYDHLTTLPHVQKY
::.:: :: .:. . : . . . : .. ....:.: : ..: : ....
CCDS45 LGMYLTDLAFIEEGTPNYTEDGLVNFSKMRMISHIIREIRQFQ--------QTAYKIEHQ
1180 1190 1200 1210 1220
270 280 290 300 310
pF1KA0 LKSVRYIEELQKFVEDDN--YKLSLRIEPGSSSPRLVSSKEDLAGPSAGSGSARFSRRPT
: ..:. . :.:: :.. :. ::::::
CCDS45 AKVTQYLLD-QSFVMDEESLYESSLRIEPKLPT
1230 1240 1250
557 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 18:40:57 2016 done: Wed Nov 2 18:40:58 2016
Total Scan time: 3.010 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]