Result of FASTA (omim) for
pF1KA0336
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0336, 1583 aa
1>>>pF1KA0336 1583 - 1583 aa - 1583 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 16.8971+/-0.000846; mu= -30.6419+/- 0.052
mean_var=806.9301+/-172.962, 0's: 0 Z-trim(114.2): 707 B-trim: 0 in 0/53
Lambda= 0.045150
statistics sampled from 23287 (23980) to 23287 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.556), E-opt: 0.2 (0.281), width: 16
Scan time: 16.260
The best scores are: opt bits E(85289)
NP_852118 (OMIM: 612711) GRIP and coiled-coil doma (1684) 9811 656.9 4.1e-187
XP_006712934 (OMIM: 612711) PREDICTED: GRIP and co (1583) 9807 656.6 4.7e-187
XP_006712933 (OMIM: 612711) PREDICTED: GRIP and co (1687) 9807 656.6 4.9e-187
XP_011510515 (OMIM: 612711) PREDICTED: GRIP and co (1572) 9741 652.3 9.2e-186
XP_006712935 (OMIM: 612711) PREDICTED: GRIP and co ( 977) 5306 363.3 5.9e-99
XP_016860333 (OMIM: 612709) PREDICTED: RANBP2-like (1480) 766 67.7 8.5e-10
XP_016860571 (OMIM: 612708) PREDICTED: RANBP2-like (1480) 766 67.7 8.5e-10
XP_016860569 (OMIM: 612708) PREDICTED: RANBP2-like (1739) 766 67.7 9.6e-10
XP_016860331 (OMIM: 612709) PREDICTED: RANBP2-like (1739) 766 67.7 9.6e-10
NP_005045 (OMIM: 612708) RANBP2-like and GRIP doma (1765) 766 67.7 9.7e-10
NP_001116835 (OMIM: 612709) RANBP2-like and GRIP d (1765) 766 67.7 9.7e-10
XP_006712857 (OMIM: 612708) PREDICTED: RANBP2-like (1791) 766 67.7 9.8e-10
XP_011510068 (OMIM: 612709) PREDICTED: RANBP2-like (1794) 766 67.7 9.8e-10
NP_001157935 (OMIM: 602752) RANBP2-like and GRIP d (1765) 760 67.3 1.3e-09
XP_011510069 (OMIM: 612709) PREDICTED: RANBP2-like (1785) 715 64.4 9.8e-09
XP_016863148 (OMIM: 117143,616051) PREDICTED: cent (2551) 715 64.5 1.3e-08
NP_001273663 (OMIM: 117143,616051) centromere-asso (2580) 715 64.5 1.3e-08
NP_872394 (OMIM: 612707) ranBP2-like and GRIP doma (1758) 704 63.7 1.6e-08
XP_011529850 (OMIM: 117143,616051) PREDICTED: cent (2604) 704 63.8 2.1e-08
XP_011529849 (OMIM: 117143,616051) PREDICTED: cent (2605) 704 63.8 2.1e-08
NP_001137485 (OMIM: 612706) ranBP2-like and GRIP d (1758) 686 62.5 3.6e-08
XP_016860227 (OMIM: 612706) PREDICTED: ranBP2-like (1766) 686 62.5 3.6e-08
NP_001019628 (OMIM: 612704) RANBP2-like and GRIP d (1748) 665 61.2 9.2e-08
NP_001071638 (OMIM: 612705) RANBP2-like and GRIP d (1756) 665 61.2 9.2e-08
XP_011531147 (OMIM: 612704) PREDICTED: RANBP2-like (1801) 665 61.2 9.4e-08
XP_016860334 (OMIM: 612705) PREDICTED: RANBP2-like (1917) 665 61.2 9.8e-08
XP_016860336 (OMIM: 612705) PREDICTED: RANBP2-like (1759) 653 60.4 1.6e-07
XP_016859594 (OMIM: 612704) PREDICTED: RANBP2-like (1760) 653 60.4 1.6e-07
XP_016859595 (OMIM: 612704) PREDICTED: RANBP2-like (1760) 653 60.4 1.6e-07
XP_016860335 (OMIM: 612705) PREDICTED: RANBP2-like (1760) 653 60.4 1.6e-07
XP_016859593 (OMIM: 612704) PREDICTED: RANBP2-like (1780) 653 60.4 1.6e-07
XP_016859592 (OMIM: 612704) PREDICTED: RANBP2-like (1805) 653 60.4 1.6e-07
NP_958783 (OMIM: 131950,226670,226730,601282,61213 (4515) 614 58.2 1.9e-06
XP_005251041 (OMIM: 131950,226670,226730,601282,61 (4520) 614 58.2 1.9e-06
XP_011515433 (OMIM: 131950,226670,226730,601282,61 (4524) 614 58.2 1.9e-06
XP_005251040 (OMIM: 131950,226670,226730,601282,61 (4524) 614 58.2 1.9e-06
NP_958781 (OMIM: 131950,226670,226730,601282,61213 (4525) 614 58.2 1.9e-06
XP_006716652 (OMIM: 131950,226670,226730,601282,61 (4529) 614 58.2 1.9e-06
XP_006716653 (OMIM: 131950,226670,226730,601282,61 (4529) 614 58.2 1.9e-06
XP_005251039 (OMIM: 131950,226670,226730,601282,61 (4530) 614 58.2 1.9e-06
NP_958780 (OMIM: 131950,226670,226730,601282,61213 (4533) 614 58.2 1.9e-06
XP_005251038 (OMIM: 131950,226670,226730,601282,61 (4538) 614 58.2 1.9e-06
NP_958784 (OMIM: 131950,226670,226730,601282,61213 (4547) 614 58.2 1.9e-06
NP_958786 (OMIM: 131950,226670,226730,601282,61213 (4547) 614 58.2 1.9e-06
NP_958785 (OMIM: 131950,226670,226730,601282,61213 (4551) 614 58.2 1.9e-06
XP_005251036 (OMIM: 131950,226670,226730,601282,61 (4552) 614 58.2 1.9e-06
XP_011515432 (OMIM: 131950,226670,226730,601282,61 (4552) 614 58.2 1.9e-06
XP_005251037 (OMIM: 131950,226670,226730,601282,61 (4552) 614 58.2 1.9e-06
XP_005251035 (OMIM: 131950,226670,226730,601282,61 (4556) 614 58.2 1.9e-06
NP_000436 (OMIM: 131950,226670,226730,601282,61213 (4574) 614 58.2 1.9e-06
>>NP_852118 (OMIM: 612711) GRIP and coiled-coil domain-c (1684 aa)
initn: 9811 init1: 9811 opt: 9811 Z-score: 3480.3 bits: 656.9 E(85289): 4.1e-187
Smith-Waterman score: 9811; 100.0% identity (100.0% similar) in 1583 aa overlap (1-1583:102-1684)
10 20 30
pF1KA0 MKQEVEDSVTKMGDAHKELEQSHINYVKEI
::::::::::::::::::::::::::::::
NP_852 KALTERLDALLLEKAETEQQCLSLKKENIKMKQEVEDSVTKMGDAHKELEQSHINYVKEI
80 90 100 110 120 130
40 50 60 70 80 90
pF1KA0 ENLKNELMAVRSKYSEDKANLQKQLEEAMNTQLELSEQLKFQNNSEDNVKKLQEEIEKIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 ENLKNELMAVRSKYSEDKANLQKQLEEAMNTQLELSEQLKFQNNSEDNVKKLQEEIEKIR
140 150 160 170 180 190
100 110 120 130 140 150
pF1KA0 PGFEEQILYLQKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 PGFEEQILYLQKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQEE
200 210 220 230 240 250
160 170 180 190 200 210
pF1KA0 VKELMCQIEASAKEHEAEINKLNELKENLVKQCEASEKNIQKKYECELENLRKATSNANQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 VKELMCQIEASAKEHEAEINKLNELKENLVKQCEASEKNIQKKYECELENLRKATSNANQ
260 270 280 290 300 310
220 230 240 250 260 270
pF1KA0 DNQICSILLQENTFVEQVVNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 DNQICSILLQENTFVEQVVNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQH
320 330 340 350 360 370
280 290 300 310 320 330
pF1KA0 IKDEFFHEREDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQFCYTVEQHNREVQSLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 IKDEFFHEREDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQFCYTVEQHNREVQSLKE
380 390 400 410 420 430
340 350 360 370 380 390
pF1KA0 QHQKEISELNETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQEAILNYESLREIMEILQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 QHQKEISELNETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQEAILNYESLREIMEILQ
440 450 460 470 480 490
400 410 420 430 440 450
pF1KA0 TELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNRLQGENEKLLSQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 TELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNRLQGENEKLLSQQ
500 510 520 530 540 550
460 470 480 490 500 510
pF1KA0 ELVPELENTIKNLQEKNGVYLLSLSQRDTMLKELEGKINSLTEEKDDFINKLKNSHEEMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 ELVPELENTIKNLQEKNGVYLLSLSQRDTMLKELEGKINSLTEEKDDFINKLKNSHEEMD
560 570 580 590 600 610
520 530 540 550 560 570
pF1KA0 NFHKKCEREERLILELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 NFHKKCEREERLILELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMV
620 630 640 650 660 670
580 590 600 610 620 630
pF1KA0 QMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKEDVILKEHITQLEKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 QMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKEDVILKEHITQLEKKL
680 690 700 710 720 730
640 650 660 670 680 690
pF1KA0 QLMVEEQDNLNKLLENEQVQKLFVKTQLYGFLKEMGSEVSEDSEEKDVVNVLQAVGESLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 QLMVEEQDNLNKLLENEQVQKLFVKTQLYGFLKEMGSEVSEDSEEKDVVNVLQAVGESLA
740 750 760 770 780 790
700 710 720 730 740 750
pF1KA0 KINEEKCNLAFQRDEKVLELEKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 KINEEKCNLAFQRDEKVLELEKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQ
800 810 820 830 840 850
760 770 780 790 800 810
pF1KA0 SEKEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 SEKEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKP
860 870 880 890 900 910
820 830 840 850 860 870
pF1KA0 LLEQKELRDRRAELILLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 LLEQKELRDRRAELILLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIK
920 930 940 950 960 970
880 890 900 910 920 930
pF1KA0 LVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 LVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSE
980 990 1000 1010 1020 1030
940 950 960 970 980 990
pF1KA0 QLDVEKERANNFEHRIEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 QLDVEKERANNFEHRIEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILE
1040 1050 1060 1070 1080 1090
1000 1010 1020 1030 1040 1050
pF1KA0 VQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 VQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKD
1100 1110 1120 1130 1140 1150
1060 1070 1080 1090 1100 1110
pF1KA0 AQQTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 AQQTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSV
1160 1170 1180 1190 1200 1210
1120 1130 1140 1150 1160 1170
pF1KA0 QQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 QQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEIT
1220 1230 1240 1250 1260 1270
1180 1190 1200 1210 1220 1230
pF1KA0 SEKHKIHEHLKTSAEQHQRTLSAYQQRVTALQEECRAAKAEQATVTSEFESYKVRVHNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 SEKHKIHEHLKTSAEQHQRTLSAYQQRVTALQEECRAAKAEQATVTSEFESYKVRVHNVL
1280 1290 1300 1310 1320 1330
1240 1250 1260 1270 1280 1290
pF1KA0 KQQKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQINVSELQTLQSEHDTLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 KQQKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQINVSELQTLQSEHDTLLE
1340 1350 1360 1370 1380 1390
1300 1310 1320 1330 1340 1350
pF1KA0 RHNKMLQETVSKEAELREKLCSIQSENMMMKSEHTQTVSQLTSQNEVLRNSFRDQVRHLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 RHNKMLQETVSKEAELREKLCSIQSENMMMKSEHTQTVSQLTSQNEVLRNSFRDQVRHLQ
1400 1410 1420 1430 1440 1450
1360 1370 1380 1390 1400 1410
pF1KA0 EEHRKTVETLQQQLSKMEAQLFQLKNEPTTRSPVSSQQSLKNLRERRNTDLPLLDMHTVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 EEHRKTVETLQQQLSKMEAQLFQLKNEPTTRSPVSSQQSLKNLRERRNTDLPLLDMHTVT
1460 1470 1480 1490 1500 1510
1420 1430 1440 1450 1460 1470
pF1KA0 REEGEGMETTDTESVSSASTYTQSLEQLLNSPETKLEPPLWHAEFTKEELVQKLSSTTKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 REEGEGMETTDTESVSSASTYTQSLEQLLNSPETKLEPPLWHAEFTKEELVQKLSSTTKS
1520 1530 1540 1550 1560 1570
1480 1490 1500 1510 1520 1530
pF1KA0 ADHLNGLLRETEATNAILMEQIKLLKSEIRRLERNQEREKSAANLEYLKNVLLQFIFLKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 ADHLNGLLRETEATNAILMEQIKLLKSEIRRLERNQEREKSAANLEYLKNVLLQFIFLKP
1580 1590 1600 1610 1620 1630
1540 1550 1560 1570 1580
pF1KA0 GSERERLLPVINTMLQLSPEEKGKLAAVAQGEEENASRSSGWASYLHSWSGLR
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 GSERERLLPVINTMLQLSPEEKGKLAAVAQGEEENASRSSGWASYLHSWSGLR
1640 1650 1660 1670 1680
>>XP_006712934 (OMIM: 612711) PREDICTED: GRIP and coiled (1583 aa)
initn: 9807 init1: 9807 opt: 9807 Z-score: 3479.2 bits: 656.6 E(85289): 4.7e-187
Smith-Waterman score: 9807; 99.9% identity (100.0% similar) in 1583 aa overlap (1-1583:1-1583)
10 20 30 40 50 60
pF1KA0 MKQEVEDSVTKMGDAHKELEQSHINYVKEIENLKNELMAVRSKYSEDKANLQKQLEEAMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MKQEVEDSVTKMGDAHKELEQSHINYVKEIENLKNELMAVRSKYSEDKANLQKQLEEAMN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 TQLELSEQLKFQNNSEDNVKKLQEEIEKIRPGFEEQILYLQKQLDATTDEKKETVTQLQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TQLELSEQLKFQNNSEDNVKKLQEEIEKIRPGFEEQILYLQKQLDATTDEKKETVTQLQN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 IIEANSQHYQKNINSLQEELLQLKAIHQEEVKELMCQIEASAKEHEAEINKLNELKENLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IIEANSQHYQKNINSLQEELLQLKAIHQEEVKELMCQIEASAKEHEAEINKLNELKENLV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 KQCEASEKNIQKKYECELENLRKATSNANQDNQICSILLQENTFVEQVVNEKVKHLEDTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KQCEASEKNIQKKYECELENLRKATSNANQDNQICSILLQENTFVEQVVNEKVKHLEDTL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 KELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHEREDLEFKINELLLAKEEQGCVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHEREDLEFKINELLLAKEEQGCVI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 EKLKSELAGLNKQFCYTVEQHNREVQSLKEQHQKEISELNETFLSDSEKEKLTLMFEIQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EKLKSELAGLNKQFCYTVEQHNREVQSLKEQHQKEISELNETFLSDSEKEKLTLMFEIQG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 LKEQCENLQQEKQEAILNYESLREIMEILQTELGESAGKISQEFESMKQQQASDVHELQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LKEQCENLQQEKQEAILNYESLREIMEILQTELGESAGKISQEFESMKQQQASDVHELQQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 KLRTAFTEKDALLETVNRLQGENEKLLSQQELVPELENTIKNLQEKNGVYLLSLSQRDTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KLRTAFTEKDALLETVNRLQGENEKLLSQQELVPELENTIKNLQEKNGVYLLSLSQRDTM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 LKELEGKINSLTEEKDDFINKLKNSHEEMDNFHKKCEREERLILELGKKVEQTIQYNSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LKELEGKINSLTEEKDDFINKLKNSHEEMDNFHKKCEREERLILELGKKVEQTIQYNSEL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 EQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 KQLSRDLEVFLSQKEDVILKEHITQLEKKLQLMVEEQDNLNKLLENEQVQKLFVKTQLYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KQLSRDLEVFLSQKEDVILKEHITQLEKKLQLMVEEQDNLNKLLENEQVQKLFVKTQLYG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 FLKEMGSEVSEDSEEKDVVNVLQAVGESLAKINEEKCNLAFQRDEKVLELEKEIKCLQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FLKEMGSEVSEDSEEKDVVNVLQAVGESLAKINEEKCNLAFQRDEKVLELEKEIKCLQEE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 SVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 VEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSLAKSPSVKND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSLAKSPSVKND
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 PLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 KDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQC
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 ETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTV
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 NELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNN
::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NELEELQVQLQKQKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNN
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 KIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETD
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 HLILQASLKGELEASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQHQRTLSAYQQRVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HLILQASLKGELEASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQHQRTLSAYQQRVTA
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 LQEECRAAKAEQATVTSEFESYKVRVHNVLKQQKNKSMSQAETEGAKQEREHLEMLIDQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQEECRAAKAEQATVTSEFESYKVRVHNVLKQQKNKSMSQAETEGAKQEREHLEMLIDQL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 KIKLQDSQNNLQINVSELQTLQSEHDTLLERHNKMLQETVSKEAELREKLCSIQSENMMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KIKLQDSQNNLQINVSELQTLQSEHDTLLERHNKMLQETVSKEAELREKLCSIQSENMMM
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 KSEHTQTVSQLTSQNEVLRNSFRDQVRHLQEEHRKTVETLQQQLSKMEAQLFQLKNEPTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KSEHTQTVSQLTSQNEVLRNSFRDQVRHLQEEHRKTVETLQQQLSKMEAQLFQLKNEPTT
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 RSPVSSQQSLKNLRERRNTDLPLLDMHTVTREEGEGMETTDTESVSSASTYTQSLEQLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RSPVSSQQSLKNLRERRNTDLPLLDMHTVTREEGEGMETTDTESVSSASTYTQSLEQLLN
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 SPETKLEPPLWHAEFTKEELVQKLSSTTKSADHLNGLLRETEATNAILMEQIKLLKSEIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SPETKLEPPLWHAEFTKEELVQKLSSTTKSADHLNGLLRETEATNAILMEQIKLLKSEIR
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 RLERNQEREKSAANLEYLKNVLLQFIFLKPGSERERLLPVINTMLQLSPEEKGKLAAVAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLERNQEREKSAANLEYLKNVLLQFIFLKPGSERERLLPVINTMLQLSPEEKGKLAAVAQ
1510 1520 1530 1540 1550 1560
1570 1580
pF1KA0 GEEENASRSSGWASYLHSWSGLR
:::::::::::::::::::::::
XP_006 GEEENASRSSGWASYLHSWSGLR
1570 1580
>>XP_006712933 (OMIM: 612711) PREDICTED: GRIP and coiled (1687 aa)
initn: 9807 init1: 9807 opt: 9807 Z-score: 3478.9 bits: 656.6 E(85289): 4.9e-187
Smith-Waterman score: 9807; 99.9% identity (100.0% similar) in 1583 aa overlap (1-1583:105-1687)
10 20 30
pF1KA0 MKQEVEDSVTKMGDAHKELEQSHINYVKEI
::::::::::::::::::::::::::::::
XP_006 KALTERLDALLLEKAETEQQCLSLKKENIKMKQEVEDSVTKMGDAHKELEQSHINYVKEI
80 90 100 110 120 130
40 50 60 70 80 90
pF1KA0 ENLKNELMAVRSKYSEDKANLQKQLEEAMNTQLELSEQLKFQNNSEDNVKKLQEEIEKIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ENLKNELMAVRSKYSEDKANLQKQLEEAMNTQLELSEQLKFQNNSEDNVKKLQEEIEKIR
140 150 160 170 180 190
100 110 120 130 140 150
pF1KA0 PGFEEQILYLQKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PGFEEQILYLQKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQEE
200 210 220 230 240 250
160 170 180 190 200 210
pF1KA0 VKELMCQIEASAKEHEAEINKLNELKENLVKQCEASEKNIQKKYECELENLRKATSNANQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VKELMCQIEASAKEHEAEINKLNELKENLVKQCEASEKNIQKKYECELENLRKATSNANQ
260 270 280 290 300 310
220 230 240 250 260 270
pF1KA0 DNQICSILLQENTFVEQVVNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DNQICSILLQENTFVEQVVNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQH
320 330 340 350 360 370
280 290 300 310 320 330
pF1KA0 IKDEFFHEREDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQFCYTVEQHNREVQSLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IKDEFFHEREDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQFCYTVEQHNREVQSLKE
380 390 400 410 420 430
340 350 360 370 380 390
pF1KA0 QHQKEISELNETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQEAILNYESLREIMEILQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QHQKEISELNETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQEAILNYESLREIMEILQ
440 450 460 470 480 490
400 410 420 430 440 450
pF1KA0 TELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNRLQGENEKLLSQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNRLQGENEKLLSQQ
500 510 520 530 540 550
460 470 480 490 500 510
pF1KA0 ELVPELENTIKNLQEKNGVYLLSLSQRDTMLKELEGKINSLTEEKDDFINKLKNSHEEMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELVPELENTIKNLQEKNGVYLLSLSQRDTMLKELEGKINSLTEEKDDFINKLKNSHEEMD
560 570 580 590 600 610
520 530 540 550 560 570
pF1KA0 NFHKKCEREERLILELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NFHKKCEREERLILELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMV
620 630 640 650 660 670
580 590 600 610 620 630
pF1KA0 QMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKEDVILKEHITQLEKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKEDVILKEHITQLEKKL
680 690 700 710 720 730
640 650 660 670 680 690
pF1KA0 QLMVEEQDNLNKLLENEQVQKLFVKTQLYGFLKEMGSEVSEDSEEKDVVNVLQAVGESLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QLMVEEQDNLNKLLENEQVQKLFVKTQLYGFLKEMGSEVSEDSEEKDVVNVLQAVGESLA
740 750 760 770 780 790
700 710 720 730 740 750
pF1KA0 KINEEKCNLAFQRDEKVLELEKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KINEEKCNLAFQRDEKVLELEKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQ
800 810 820 830 840 850
760 770 780 790 800 810
pF1KA0 SEKEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SEKEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKP
860 870 880 890 900 910
820 830 840 850 860 870
pF1KA0 LLEQKELRDRRAELILLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLEQKELRDRRAELILLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIK
920 930 940 950 960 970
880 890 900 910 920 930
pF1KA0 LVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSE
980 990 1000 1010 1020 1030
940 950 960 970 980 990
pF1KA0 QLDVEKERANNFEHRIEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QLDVEKERANNFEHRIEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILE
1040 1050 1060 1070 1080 1090
1000 1010 1020 1030 1040 1050
pF1KA0 VQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKD
::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::
XP_006 VQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKQKKQLQKTMQELELVKKD
1100 1110 1120 1130 1140 1150
1060 1070 1080 1090 1100 1110
pF1KA0 AQQTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AQQTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSV
1160 1170 1180 1190 1200 1210
1120 1130 1140 1150 1160 1170
pF1KA0 QQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEIT
1220 1230 1240 1250 1260 1270
1180 1190 1200 1210 1220 1230
pF1KA0 SEKHKIHEHLKTSAEQHQRTLSAYQQRVTALQEECRAAKAEQATVTSEFESYKVRVHNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SEKHKIHEHLKTSAEQHQRTLSAYQQRVTALQEECRAAKAEQATVTSEFESYKVRVHNVL
1280 1290 1300 1310 1320 1330
1240 1250 1260 1270 1280 1290
pF1KA0 KQQKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQINVSELQTLQSEHDTLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KQQKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQINVSELQTLQSEHDTLLE
1340 1350 1360 1370 1380 1390
1300 1310 1320 1330 1340 1350
pF1KA0 RHNKMLQETVSKEAELREKLCSIQSENMMMKSEHTQTVSQLTSQNEVLRNSFRDQVRHLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RHNKMLQETVSKEAELREKLCSIQSENMMMKSEHTQTVSQLTSQNEVLRNSFRDQVRHLQ
1400 1410 1420 1430 1440 1450
1360 1370 1380 1390 1400 1410
pF1KA0 EEHRKTVETLQQQLSKMEAQLFQLKNEPTTRSPVSSQQSLKNLRERRNTDLPLLDMHTVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EEHRKTVETLQQQLSKMEAQLFQLKNEPTTRSPVSSQQSLKNLRERRNTDLPLLDMHTVT
1460 1470 1480 1490 1500 1510
1420 1430 1440 1450 1460 1470
pF1KA0 REEGEGMETTDTESVSSASTYTQSLEQLLNSPETKLEPPLWHAEFTKEELVQKLSSTTKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 REEGEGMETTDTESVSSASTYTQSLEQLLNSPETKLEPPLWHAEFTKEELVQKLSSTTKS
1520 1530 1540 1550 1560 1570
1480 1490 1500 1510 1520 1530
pF1KA0 ADHLNGLLRETEATNAILMEQIKLLKSEIRRLERNQEREKSAANLEYLKNVLLQFIFLKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ADHLNGLLRETEATNAILMEQIKLLKSEIRRLERNQEREKSAANLEYLKNVLLQFIFLKP
1580 1590 1600 1610 1620 1630
1540 1550 1560 1570 1580
pF1KA0 GSERERLLPVINTMLQLSPEEKGKLAAVAQGEEENASRSSGWASYLHSWSGLR
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GSERERLLPVINTMLQLSPEEKGKLAAVAQGEEENASRSSGWASYLHSWSGLR
1640 1650 1660 1670 1680
>>XP_011510515 (OMIM: 612711) PREDICTED: GRIP and coiled (1572 aa)
initn: 9741 init1: 9741 opt: 9741 Z-score: 3456.0 bits: 652.3 E(85289): 9.2e-186
Smith-Waterman score: 9741; 99.9% identity (100.0% similar) in 1572 aa overlap (12-1583:1-1572)
10 20 30 40 50 60
pF1KA0 MKQEVEDSVTKMGDAHKELEQSHINYVKEIENLKNELMAVRSKYSEDKANLQKQLEEAMN
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGDAHKELEQSHINYVKEIENLKNELMAVRSKYSEDKANLQKQLEEAMN
10 20 30 40
70 80 90 100 110 120
pF1KA0 TQLELSEQLKFQNNSEDNVKKLQEEIEKIRPGFEEQILYLQKQLDATTDEKKETVTQLQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQLELSEQLKFQNNSEDNVKKLQEEIEKIRPGFEEQILYLQKQLDATTDEKKETVTQLQN
50 60 70 80 90 100
130 140 150 160 170 180
pF1KA0 IIEANSQHYQKNINSLQEELLQLKAIHQEEVKELMCQIEASAKEHEAEINKLNELKENLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IIEANSQHYQKNINSLQEELLQLKAIHQEEVKELMCQIEASAKEHEAEINKLNELKENLV
110 120 130 140 150 160
190 200 210 220 230 240
pF1KA0 KQCEASEKNIQKKYECELENLRKATSNANQDNQICSILLQENTFVEQVVNEKVKHLEDTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQCEASEKNIQKKYECELENLRKATSNANQDNQICSILLQENTFVEQVVNEKVKHLEDTL
170 180 190 200 210 220
250 260 270 280 290 300
pF1KA0 KELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHEREDLEFKINELLLAKEEQGCVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHEREDLEFKINELLLAKEEQGCVI
230 240 250 260 270 280
310 320 330 340 350 360
pF1KA0 EKLKSELAGLNKQFCYTVEQHNREVQSLKEQHQKEISELNETFLSDSEKEKLTLMFEIQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLKSELAGLNKQFCYTVEQHNREVQSLKEQHQKEISELNETFLSDSEKEKLTLMFEIQG
290 300 310 320 330 340
370 380 390 400 410 420
pF1KA0 LKEQCENLQQEKQEAILNYESLREIMEILQTELGESAGKISQEFESMKQQQASDVHELQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKEQCENLQQEKQEAILNYESLREIMEILQTELGESAGKISQEFESMKQQQASDVHELQQ
350 360 370 380 390 400
430 440 450 460 470 480
pF1KA0 KLRTAFTEKDALLETVNRLQGENEKLLSQQELVPELENTIKNLQEKNGVYLLSLSQRDTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLRTAFTEKDALLETVNRLQGENEKLLSQQELVPELENTIKNLQEKNGVYLLSLSQRDTM
410 420 430 440 450 460
490 500 510 520 530 540
pF1KA0 LKELEGKINSLTEEKDDFINKLKNSHEEMDNFHKKCEREERLILELGKKVEQTIQYNSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKELEGKINSLTEEKDDFINKLKNSHEEMDNFHKKCEREERLILELGKKVEQTIQYNSEL
470 480 490 500 510 520
550 560 570 580 590 600
pF1KA0 EQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEK
530 540 550 560 570 580
610 620 630 640 650 660
pF1KA0 KQLSRDLEVFLSQKEDVILKEHITQLEKKLQLMVEEQDNLNKLLENEQVQKLFVKTQLYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQLSRDLEVFLSQKEDVILKEHITQLEKKLQLMVEEQDNLNKLLENEQVQKLFVKTQLYG
590 600 610 620 630 640
670 680 690 700 710 720
pF1KA0 FLKEMGSEVSEDSEEKDVVNVLQAVGESLAKINEEKCNLAFQRDEKVLELEKEIKCLQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLKEMGSEVSEDSEEKDVVNVLQAVGESLAKINEEKCNLAFQRDEKVLELEKEIKCLQEE
650 660 670 680 690 700
730 740 750 760 770 780
pF1KA0 SVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQ
710 720 730 740 750 760
790 800 810 820 830 840
pF1KA0 VEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSLAKSPSVKND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSLAKSPSVKND
770 780 790 800 810 820
850 860 870 880 890 900
pF1KA0 PLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSE
830 840 850 860 870 880
910 920 930 940 950 960
pF1KA0 KDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQC
890 900 910 920 930 940
970 980 990 1000 1010 1020
pF1KA0 ETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTV
950 960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KA0 NELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNN
::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NELEELQVQLQKQKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNN
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KA0 KIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETD
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KA0 HLILQASLKGELEASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQHQRTLSAYQQRVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLILQASLKGELEASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQHQRTLSAYQQRVTA
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KA0 LQEECRAAKAEQATVTSEFESYKVRVHNVLKQQKNKSMSQAETEGAKQEREHLEMLIDQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQEECRAAKAEQATVTSEFESYKVRVHNVLKQQKNKSMSQAETEGAKQEREHLEMLIDQL
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
pF1KA0 KIKLQDSQNNLQINVSELQTLQSEHDTLLERHNKMLQETVSKEAELREKLCSIQSENMMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIKLQDSQNNLQINVSELQTLQSEHDTLLERHNKMLQETVSKEAELREKLCSIQSENMMM
1250 1260 1270 1280 1290 1300
1330 1340 1350 1360 1370 1380
pF1KA0 KSEHTQTVSQLTSQNEVLRNSFRDQVRHLQEEHRKTVETLQQQLSKMEAQLFQLKNEPTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSEHTQTVSQLTSQNEVLRNSFRDQVRHLQEEHRKTVETLQQQLSKMEAQLFQLKNEPTT
1310 1320 1330 1340 1350 1360
1390 1400 1410 1420 1430 1440
pF1KA0 RSPVSSQQSLKNLRERRNTDLPLLDMHTVTREEGEGMETTDTESVSSASTYTQSLEQLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSPVSSQQSLKNLRERRNTDLPLLDMHTVTREEGEGMETTDTESVSSASTYTQSLEQLLN
1370 1380 1390 1400 1410 1420
1450 1460 1470 1480 1490 1500
pF1KA0 SPETKLEPPLWHAEFTKEELVQKLSSTTKSADHLNGLLRETEATNAILMEQIKLLKSEIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPETKLEPPLWHAEFTKEELVQKLSSTTKSADHLNGLLRETEATNAILMEQIKLLKSEIR
1430 1440 1450 1460 1470 1480
1510 1520 1530 1540 1550 1560
pF1KA0 RLERNQEREKSAANLEYLKNVLLQFIFLKPGSERERLLPVINTMLQLSPEEKGKLAAVAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLERNQEREKSAANLEYLKNVLLQFIFLKPGSERERLLPVINTMLQLSPEEKGKLAAVAQ
1490 1500 1510 1520 1530 1540
1570 1580
pF1KA0 GEEENASRSSGWASYLHSWSGLR
:::::::::::::::::::::::
XP_011 GEEENASRSSGWASYLHSWSGLR
1550 1560 1570
>>XP_006712935 (OMIM: 612711) PREDICTED: GRIP and coiled (977 aa)
initn: 5306 init1: 5306 opt: 5306 Z-score: 1897.6 bits: 363.3 E(85289): 5.9e-99
Smith-Waterman score: 5306; 100.0% identity (100.0% similar) in 852 aa overlap (1-852:105-956)
10 20 30
pF1KA0 MKQEVEDSVTKMGDAHKELEQSHINYVKEI
::::::::::::::::::::::::::::::
XP_006 KALTERLDALLLEKAETEQQCLSLKKENIKMKQEVEDSVTKMGDAHKELEQSHINYVKEI
80 90 100 110 120 130
40 50 60 70 80 90
pF1KA0 ENLKNELMAVRSKYSEDKANLQKQLEEAMNTQLELSEQLKFQNNSEDNVKKLQEEIEKIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ENLKNELMAVRSKYSEDKANLQKQLEEAMNTQLELSEQLKFQNNSEDNVKKLQEEIEKIR
140 150 160 170 180 190
100 110 120 130 140 150
pF1KA0 PGFEEQILYLQKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PGFEEQILYLQKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQEE
200 210 220 230 240 250
160 170 180 190 200 210
pF1KA0 VKELMCQIEASAKEHEAEINKLNELKENLVKQCEASEKNIQKKYECELENLRKATSNANQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VKELMCQIEASAKEHEAEINKLNELKENLVKQCEASEKNIQKKYECELENLRKATSNANQ
260 270 280 290 300 310
220 230 240 250 260 270
pF1KA0 DNQICSILLQENTFVEQVVNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DNQICSILLQENTFVEQVVNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQH
320 330 340 350 360 370
280 290 300 310 320 330
pF1KA0 IKDEFFHEREDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQFCYTVEQHNREVQSLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IKDEFFHEREDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQFCYTVEQHNREVQSLKE
380 390 400 410 420 430
340 350 360 370 380 390
pF1KA0 QHQKEISELNETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQEAILNYESLREIMEILQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QHQKEISELNETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQEAILNYESLREIMEILQ
440 450 460 470 480 490
400 410 420 430 440 450
pF1KA0 TELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNRLQGENEKLLSQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNRLQGENEKLLSQQ
500 510 520 530 540 550
460 470 480 490 500 510
pF1KA0 ELVPELENTIKNLQEKNGVYLLSLSQRDTMLKELEGKINSLTEEKDDFINKLKNSHEEMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELVPELENTIKNLQEKNGVYLLSLSQRDTMLKELEGKINSLTEEKDDFINKLKNSHEEMD
560 570 580 590 600 610
520 530 540 550 560 570
pF1KA0 NFHKKCEREERLILELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NFHKKCEREERLILELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMV
620 630 640 650 660 670
580 590 600 610 620 630
pF1KA0 QMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKEDVILKEHITQLEKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKEDVILKEHITQLEKKL
680 690 700 710 720 730
640 650 660 670 680 690
pF1KA0 QLMVEEQDNLNKLLENEQVQKLFVKTQLYGFLKEMGSEVSEDSEEKDVVNVLQAVGESLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QLMVEEQDNLNKLLENEQVQKLFVKTQLYGFLKEMGSEVSEDSEEKDVVNVLQAVGESLA
740 750 760 770 780 790
700 710 720 730 740 750
pF1KA0 KINEEKCNLAFQRDEKVLELEKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KINEEKCNLAFQRDEKVLELEKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQ
800 810 820 830 840 850
760 770 780 790 800 810
pF1KA0 SEKEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SEKEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKP
860 870 880 890 900 910
820 830 840 850 860 870
pF1KA0 LLEQKELRDRRAELILLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIK
::::::::::::::::::::::::::::::::::::::::::
XP_006 LLEQKELRDRRAELILLKDSLAKSPSVKNDPLSSVKELEEKIGKNRLERGKLLLQKKEGE
920 930 940 950 960 970
880 890 900 910 920 930
pF1KA0 LVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSE
XP_006 LLL
>>XP_016860333 (OMIM: 612709) PREDICTED: RANBP2-like and (1480 aa)
initn: 789 init1: 753 opt: 766 Z-score: 296.9 bits: 67.7 E(85289): 8.5e-10
Smith-Waterman score: 809; 29.7% identity (59.1% similar) in 750 aa overlap (851-1571:780-1480)
830 840 850 860 870
pF1KA0 RAELILLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKE-KEEKINKIKLVAVKAKKE
:. .. : .. ::. ....:.. ... .
XP_016 IHFEPVVQMPEKVELVTGEEGEKVLYSQGVKLFRFDAEVRQWKERGLGNLKILKNEVNGK
750 760 770 780 790 800
880 890 900 910 920 930
pF1KA0 LDSSRKETQTVK---EELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEK
: .. :..: .. . . ::.: : . .: .... . :. . .. .
XP_016 LRMLMRREQVLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGDAKLERLAAKFKTP-
810 820 830 840 850 860
940 950 960 970 980 990
pF1KA0 ERANNFEHRIEDLTRQLRNSTLQCETINSDN---EDLLARIETLQSNAKLLEVQILEVQR
: :..:....:. : : . :: :. :. : : ..:. : ... .: ..
XP_016 ELAEEFKQKFEECQRLLLDIPLQTPHKLVDTGRAAKLIQRAEEMKSGLKDFKT-FLTNDQ
870 880 890 900 910 920
1000 1010 1020 1030 1040 1050
pF1KA0 AKAMVDKELEAEKLQKEQKIKEHATTVN-ELEELQVQLQKEKKQLQKTMQELELVKKDAQ
.:. : .: . ::.. . :. :. .. .:.. . . .....
XP_016 TKV----TEEENKGSGTGAAGASDTTIKPNAENTGPTLEWDNYDLREDALDDSVSSSSVH
930 940 950 960 970 980
1060 1070 1080 1090 1100 1110
pF1KA0 QTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQ
. : . . .. . ..... :..: .... . : . ... :. .: : :
XP_016 ASPLASSPV---RKNLFRFDESTTGSNFSFKSALSLSKSPAKLNQSGTSVGTDEESVVTQ
990 1000 1010 1020 1030 1040
1120 1130 1140 1150 1160 1170
pF1KA0 YEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSE
::.. . . .: . :. :....... ...:.:. . .. .
XP_016 EEERDGQYFEPVVPLPDLVEVSSGEENEQVVFS-----------HRAEIYRYD-KDVGQW
1050 1060 1070 1080
1180 1190 1200 1210 1220 1230
pF1KA0 KHKIHEHLKTSAEQHQRTLSAYQQRVTALQEECRAAKAEQATVTSEFESYKVRVHNVLKQ
:.. .: . .. . ..: .:. : . .: . . ..:.
XP_016 KERGIGDIKILQNYDNKQVRIVMRRDQVLKL-CANHR-----ITPD-----MSLQNMKGT
1090 1100 1110 1120 1130
1240 1250 1260 1270 1280 1290
pF1KA0 QKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQINVSELQTLQSEHDTLLERH
.. . . .... ::: . ..:::: .... .: .: : :.:.:. :
XP_016 ERVWVWTACDFADGERKVEHLAV-----RFKLQDVADSFKKIFDEAKTAQ-EKDSLITPH
1140 1150 1160 1170 1180 1190
1300 1310 1320 1330 1340 1350
pF1KA0 NKMLQETVSKEAELREKLCSIQSENMMMKSEHTQTVSQLTSQNEVLRNSFRDQVRHLQEE
::. . ::. :. . .. : :. ... . ..: . . .: .:
XP_016 -------VSRSSTPRESPCGKIAVAIL--EETTRERTDVIQGDDVADAASEVEVSSTSET
1200 1210 1220 1230 1240
1360 1370 1380 1390
pF1KA0 HRKTV----------ETLQQQLSKMEAQLFQLKNEPTTRS--------PVSSQQSLKNLR
:.: :.... .:. ... : . : .: : :..:..: .
XP_016 TTKAVVSPPKFVFVSESVKRIFSSEKSKPFVFGNSSATGSLFGFSFNAPLKSNNSETSSV
1250 1260 1270 1280 1290 1300
1400 1410 1420 1430 1440 1450
pF1KA0 ERRNTDLPLLDMHTVTREEGEGMETTDTESVS-SASTYTQ--SLEQLLNSPETKLEPPLW
. ... . . .... ...:.. . ::: :. :.. ...:: :::::
XP_016 AQSGSESKVEPKKCELSKNSDIEQSSDSKVKNLSASFPTEESSINYTFKTPEK--EPPLW
1310 1320 1330 1340 1350 1360
1460 1470 1480 1490 1500 1510
pF1KA0 HAEFTKEELVQKLSSTTKSADHLNGLLRETEATNAILMEQIKLLKSEIRRLERNQEREKS
::::::::::::: ::::::::::::::: :::::.::::::::::::::::::::::::
XP_016 HAEFTKEELVQKLRSTTKSADHLNGLLREIEATNAVLMEQIKLLKSEIRRLERNQEREKS
1370 1380 1390 1400 1410 1420
1520 1530 1540 1550 1560 1570
pF1KA0 AANLEYLKNVLLQFIFLKPGSERERLLPVINTMLQLSPEEKGKLAAVAQGEEENASRSSG
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_016 AANLEYLKNVLLQFIFLKPGSERERLLPVINTMLQLSPEEKGKLAAVAQDEEENASRSSG
1430 1440 1450 1460 1470 1480
1580
pF1KA0 WASYLHSWSGLR
>>XP_016860571 (OMIM: 612708) PREDICTED: RANBP2-like and (1480 aa)
initn: 789 init1: 753 opt: 766 Z-score: 296.9 bits: 67.7 E(85289): 8.5e-10
Smith-Waterman score: 809; 29.7% identity (59.1% similar) in 750 aa overlap (851-1571:780-1480)
830 840 850 860 870
pF1KA0 RAELILLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKE-KEEKINKIKLVAVKAKKE
:. .. : .. ::. ....:.. ... .
XP_016 IHFEPVVQMPEKVELVTGEEGEKVLYSQGVKLFRFDAEVRQWKERGLGNLKILKNEVNGK
750 760 770 780 790 800
880 890 900 910 920 930
pF1KA0 LDSSRKETQTVK---EELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEK
: .. :..: .. . . ::.: : . .: .... . :. . .. .
XP_016 LRMLMRREQVLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGDAKLERLAAKFKTP-
810 820 830 840 850 860
940 950 960 970 980 990
pF1KA0 ERANNFEHRIEDLTRQLRNSTLQCETINSDN---EDLLARIETLQSNAKLLEVQILEVQR
: :..:....:. : : . :: :. :. : : ..:. : ... .: ..
XP_016 ELAEEFKQKFEECQRLLLDIPLQTPHKLVDTGRAAKLIQRAEEMKSGLKDFKT-FLTNDQ
870 880 890 900 910 920
1000 1010 1020 1030 1040 1050
pF1KA0 AKAMVDKELEAEKLQKEQKIKEHATTVN-ELEELQVQLQKEKKQLQKTMQELELVKKDAQ
.:. : .: . ::.. . :. :. .. .:.. . . .....
XP_016 TKV----TEEENKGSGTGAAGASDTTIKPNAENTGPTLEWDNYDLREDALDDSVSSSSVH
930 940 950 960 970 980
1060 1070 1080 1090 1100 1110
pF1KA0 QTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQ
. : . . .. . ..... :..: .... . : . ... :. .: : :
XP_016 ASPLASSPV---RKNLFRFDESTTGSNFSFKSALSLSKSPAKLNQSGTSVGTDEESVVTQ
990 1000 1010 1020 1030 1040
1120 1130 1140 1150 1160 1170
pF1KA0 YEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSE
::.. . . .: . :. :....... ...:.:. . .. .
XP_016 EEERDGQYFEPVVPLPDLVEVSSGEENEQVVFS-----------HRAEIYRYD-KDVGQW
1050 1060 1070 1080
1180 1190 1200 1210 1220 1230
pF1KA0 KHKIHEHLKTSAEQHQRTLSAYQQRVTALQEECRAAKAEQATVTSEFESYKVRVHNVLKQ
:.. .: . .. . ..: .:. : . .: . . ..:.
XP_016 KERGIGDIKILQNYDNKQVRIVMRRDQVLKL-CANHR-----ITPD-----MSLQNMKGT
1090 1100 1110 1120 1130
1240 1250 1260 1270 1280 1290
pF1KA0 QKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQINVSELQTLQSEHDTLLERH
.. . . .... ::: . ..:::: .... .: .: : :.:.:. :
XP_016 ERVWVWTACDFADGERKVEHLAV-----RFKLQDVADSFKKIFDEAKTAQ-EKDSLITPH
1140 1150 1160 1170 1180 1190
1300 1310 1320 1330 1340 1350
pF1KA0 NKMLQETVSKEAELREKLCSIQSENMMMKSEHTQTVSQLTSQNEVLRNSFRDQVRHLQEE
::. . ::. :. . .. : :. ... . ..: . . .: .:
XP_016 -------VSRSSTPRESPCGKIAVAIL--EETTRERTDVIQGDDVADAASEVEVSSTSET
1200 1210 1220 1230 1240
1360 1370 1380 1390
pF1KA0 HRKTV----------ETLQQQLSKMEAQLFQLKNEPTTRS--------PVSSQQSLKNLR
:.: :.... .:. ... : . : .: : :..:..: .
XP_016 TTKAVVSPPKFVFVSESVKRIFSSEKSKPFVFGNSSATGSLFGFSFNAPLKSNNSETSSV
1250 1260 1270 1280 1290 1300
1400 1410 1420 1430 1440 1450
pF1KA0 ERRNTDLPLLDMHTVTREEGEGMETTDTESVS-SASTYTQ--SLEQLLNSPETKLEPPLW
. ... . . .... ...:.. . ::: :. :.. ...:: :::::
XP_016 AQSGSESKVEPKKCELSKNSDIEQSSDSKVKNLSASFPTEESSINYTFKTPEK--EPPLW
1310 1320 1330 1340 1350 1360
1460 1470 1480 1490 1500 1510
pF1KA0 HAEFTKEELVQKLSSTTKSADHLNGLLRETEATNAILMEQIKLLKSEIRRLERNQEREKS
::::::::::::: ::::::::::::::: :::::.::::::::::::::::::::::::
XP_016 HAEFTKEELVQKLRSTTKSADHLNGLLREIEATNAVLMEQIKLLKSEIRRLERNQEREKS
1370 1380 1390 1400 1410 1420
1520 1530 1540 1550 1560 1570
pF1KA0 AANLEYLKNVLLQFIFLKPGSERERLLPVINTMLQLSPEEKGKLAAVAQGEEENASRSSG
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_016 AANLEYLKNVLLQFIFLKPGSERERLLPVINTMLQLSPEEKGKLAAVAQDEEENASRSSG
1430 1440 1450 1460 1470 1480
1580
pF1KA0 WASYLHSWSGLR
>>XP_016860569 (OMIM: 612708) PREDICTED: RANBP2-like and (1739 aa)
initn: 789 init1: 753 opt: 766 Z-score: 296.0 bits: 67.7 E(85289): 9.6e-10
Smith-Waterman score: 809; 29.7% identity (59.1% similar) in 750 aa overlap (851-1571:1039-1739)
830 840 850 860 870
pF1KA0 RAELILLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKE-KEEKINKIKLVAVKAKKE
:. .. : .. ::. ....:.. ... .
XP_016 IHFEPVVQMPEKVELVTGEEGEKVLYSQGVKLFRFDAEVRQWKERGLGNLKILKNEVNGK
1010 1020 1030 1040 1050 1060
880 890 900 910 920 930
pF1KA0 LDSSRKETQTVK---EELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEK
: .. :..: .. . . ::.: : . .: .... . :. . .. .
XP_016 LRMLMRREQVLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGDAKLERLAAKFKTP-
1070 1080 1090 1100 1110 1120
940 950 960 970 980 990
pF1KA0 ERANNFEHRIEDLTRQLRNSTLQCETINSDN---EDLLARIETLQSNAKLLEVQILEVQR
: :..:....:. : : . :: :. :. : : ..:. : ... .: ..
XP_016 ELAEEFKQKFEECQRLLLDIPLQTPHKLVDTGRAAKLIQRAEEMKSGLKDFKT-FLTNDQ
1130 1140 1150 1160 1170 1180
1000 1010 1020 1030 1040 1050
pF1KA0 AKAMVDKELEAEKLQKEQKIKEHATTVN-ELEELQVQLQKEKKQLQKTMQELELVKKDAQ
.:. : .: . ::.. . :. :. .. .:.. . . .....
XP_016 TKV----TEEENKGSGTGAAGASDTTIKPNAENTGPTLEWDNYDLREDALDDSVSSSSVH
1190 1200 1210 1220 1230 1240
1060 1070 1080 1090 1100 1110
pF1KA0 QTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQ
. : . . .. . ..... :..: .... . : . ... :. .: : :
XP_016 ASPLASSPV---RKNLFRFDESTTGSNFSFKSALSLSKSPAKLNQSGTSVGTDEESVVTQ
1250 1260 1270 1280 1290
1120 1130 1140 1150 1160 1170
pF1KA0 YEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSE
::.. . . .: . :. :....... ...:.:. . .. .
XP_016 EEERDGQYFEPVVPLPDLVEVSSGEENEQVVFS-----------HRAEIYRYD-KDVGQW
1300 1310 1320 1330 1340
1180 1190 1200 1210 1220 1230
pF1KA0 KHKIHEHLKTSAEQHQRTLSAYQQRVTALQEECRAAKAEQATVTSEFESYKVRVHNVLKQ
:.. .: . .. . ..: .:. : . .: . . ..:.
XP_016 KERGIGDIKILQNYDNKQVRIVMRRDQVLKL-CANHR-----ITPD-----MSLQNMKGT
1350 1360 1370 1380 1390
1240 1250 1260 1270 1280 1290
pF1KA0 QKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQINVSELQTLQSEHDTLLERH
.. . . .... ::: . ..:::: .... .: .: : :.:.:. :
XP_016 ERVWVWTACDFADGERKVEHLAV-----RFKLQDVADSFKKIFDEAKTAQ-EKDSLITPH
1400 1410 1420 1430 1440 1450
1300 1310 1320 1330 1340 1350
pF1KA0 NKMLQETVSKEAELREKLCSIQSENMMMKSEHTQTVSQLTSQNEVLRNSFRDQVRHLQEE
::. . ::. :. . .. : :. ... . ..: . . .: .:
XP_016 -------VSRSSTPRESPCGKIAVAIL--EETTRERTDVIQGDDVADAASEVEVSSTSET
1460 1470 1480 1490 1500
1360 1370 1380 1390
pF1KA0 HRKTV----------ETLQQQLSKMEAQLFQLKNEPTTRS--------PVSSQQSLKNLR
:.: :.... .:. ... : . : .: : :..:..: .
XP_016 TTKAVVSPPKFVFVSESVKRIFSSEKSKPFVFGNSSATGSLFGFSFNAPLKSNNSETSSV
1510 1520 1530 1540 1550 1560
1400 1410 1420 1430 1440 1450
pF1KA0 ERRNTDLPLLDMHTVTREEGEGMETTDTESVS-SASTYTQ--SLEQLLNSPETKLEPPLW
. ... . . .... ...:.. . ::: :. :.. ...:: :::::
XP_016 AQSGSESKVEPKKCELSKNSDIEQSSDSKVKNLSASFPTEESSINYTFKTPEK--EPPLW
1570 1580 1590 1600 1610
1460 1470 1480 1490 1500 1510
pF1KA0 HAEFTKEELVQKLSSTTKSADHLNGLLRETEATNAILMEQIKLLKSEIRRLERNQEREKS
::::::::::::: ::::::::::::::: :::::.::::::::::::::::::::::::
XP_016 HAEFTKEELVQKLRSTTKSADHLNGLLREIEATNAVLMEQIKLLKSEIRRLERNQEREKS
1620 1630 1640 1650 1660 1670
1520 1530 1540 1550 1560 1570
pF1KA0 AANLEYLKNVLLQFIFLKPGSERERLLPVINTMLQLSPEEKGKLAAVAQGEEENASRSSG
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_016 AANLEYLKNVLLQFIFLKPGSERERLLPVINTMLQLSPEEKGKLAAVAQDEEENASRSSG
1680 1690 1700 1710 1720 1730
1580
pF1KA0 WASYLHSWSGLR
>>XP_016860331 (OMIM: 612709) PREDICTED: RANBP2-like and (1739 aa)
initn: 789 init1: 753 opt: 766 Z-score: 296.0 bits: 67.7 E(85289): 9.6e-10
Smith-Waterman score: 809; 29.7% identity (59.1% similar) in 750 aa overlap (851-1571:1039-1739)
830 840 850 860 870
pF1KA0 RAELILLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKE-KEEKINKIKLVAVKAKKE
:. .. : .. ::. ....:.. ... .
XP_016 IHFEPVVQMPEKVELVTGEEGEKVLYSQGVKLFRFDAEVRQWKERGLGNLKILKNEVNGK
1010 1020 1030 1040 1050 1060
880 890 900 910 920 930
pF1KA0 LDSSRKETQTVK---EELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEK
: .. :..: .. . . ::.: : . .: .... . :. . .. .
XP_016 LRMLMRREQVLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGDAKLERLAAKFKTP-
1070 1080 1090 1100 1110 1120
940 950 960 970 980 990
pF1KA0 ERANNFEHRIEDLTRQLRNSTLQCETINSDN---EDLLARIETLQSNAKLLEVQILEVQR
: :..:....:. : : . :: :. :. : : ..:. : ... .: ..
XP_016 ELAEEFKQKFEECQRLLLDIPLQTPHKLVDTGRAAKLIQRAEEMKSGLKDFKT-FLTNDQ
1130 1140 1150 1160 1170 1180
1000 1010 1020 1030 1040 1050
pF1KA0 AKAMVDKELEAEKLQKEQKIKEHATTVN-ELEELQVQLQKEKKQLQKTMQELELVKKDAQ
.:. : .: . ::.. . :. :. .. .:.. . . .....
XP_016 TKV----TEEENKGSGTGAAGASDTTIKPNAENTGPTLEWDNYDLREDALDDSVSSSSVH
1190 1200 1210 1220 1230 1240
1060 1070 1080 1090 1100 1110
pF1KA0 QTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQ
. : . . .. . ..... :..: .... . : . ... :. .: : :
XP_016 ASPLASSPV---RKNLFRFDESTTGSNFSFKSALSLSKSPAKLNQSGTSVGTDEESVVTQ
1250 1260 1270 1280 1290
1120 1130 1140 1150 1160 1170
pF1KA0 YEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSE
::.. . . .: . :. :....... ...:.:. . .. .
XP_016 EEERDGQYFEPVVPLPDLVEVSSGEENEQVVFS-----------HRAEIYRYD-KDVGQW
1300 1310 1320 1330 1340
1180 1190 1200 1210 1220 1230
pF1KA0 KHKIHEHLKTSAEQHQRTLSAYQQRVTALQEECRAAKAEQATVTSEFESYKVRVHNVLKQ
:.. .: . .. . ..: .:. : . .: . . ..:.
XP_016 KERGIGDIKILQNYDNKQVRIVMRRDQVLKL-CANHR-----ITPD-----MSLQNMKGT
1350 1360 1370 1380 1390
1240 1250 1260 1270 1280 1290
pF1KA0 QKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQINVSELQTLQSEHDTLLERH
.. . . .... ::: . ..:::: .... .: .: : :.:.:. :
XP_016 ERVWVWTACDFADGERKVEHLAV-----RFKLQDVADSFKKIFDEAKTAQ-EKDSLITPH
1400 1410 1420 1430 1440 1450
1300 1310 1320 1330 1340 1350
pF1KA0 NKMLQETVSKEAELREKLCSIQSENMMMKSEHTQTVSQLTSQNEVLRNSFRDQVRHLQEE
::. . ::. :. . .. : :. ... . ..: . . .: .:
XP_016 -------VSRSSTPRESPCGKIAVAIL--EETTRERTDVIQGDDVADAASEVEVSSTSET
1460 1470 1480 1490 1500
1360 1370 1380 1390
pF1KA0 HRKTV----------ETLQQQLSKMEAQLFQLKNEPTTRS--------PVSSQQSLKNLR
:.: :.... .:. ... : . : .: : :..:..: .
XP_016 TTKAVVSPPKFVFVSESVKRIFSSEKSKPFVFGNSSATGSLFGFSFNAPLKSNNSETSSV
1510 1520 1530 1540 1550 1560
1400 1410 1420 1430 1440 1450
pF1KA0 ERRNTDLPLLDMHTVTREEGEGMETTDTESVS-SASTYTQ--SLEQLLNSPETKLEPPLW
. ... . . .... ...:.. . ::: :. :.. ...:: :::::
XP_016 AQSGSESKVEPKKCELSKNSDIEQSSDSKVKNLSASFPTEESSINYTFKTPEK--EPPLW
1570 1580 1590 1600 1610
1460 1470 1480 1490 1500 1510
pF1KA0 HAEFTKEELVQKLSSTTKSADHLNGLLRETEATNAILMEQIKLLKSEIRRLERNQEREKS
::::::::::::: ::::::::::::::: :::::.::::::::::::::::::::::::
XP_016 HAEFTKEELVQKLRSTTKSADHLNGLLREIEATNAVLMEQIKLLKSEIRRLERNQEREKS
1620 1630 1640 1650 1660 1670
1520 1530 1540 1550 1560 1570
pF1KA0 AANLEYLKNVLLQFIFLKPGSERERLLPVINTMLQLSPEEKGKLAAVAQGEEENASRSSG
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_016 AANLEYLKNVLLQFIFLKPGSERERLLPVINTMLQLSPEEKGKLAAVAQDEEENASRSSG
1680 1690 1700 1710 1720 1730
1580
pF1KA0 WASYLHSWSGLR
>>NP_005045 (OMIM: 612708) RANBP2-like and GRIP domain-c (1765 aa)
initn: 789 init1: 753 opt: 766 Z-score: 295.9 bits: 67.7 E(85289): 9.7e-10
Smith-Waterman score: 809; 29.7% identity (59.1% similar) in 750 aa overlap (851-1571:1065-1765)
830 840 850 860 870
pF1KA0 RAELILLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKE-KEEKINKIKLVAVKAKKE
:. .. : .. ::. ....:.. ... .
NP_005 IHFEPVVQMPEKVELVTGEEGEKVLYSQGVKLFRFDAEVRQWKERGLGNLKILKNEVNGK
1040 1050 1060 1070 1080 1090
880 890 900 910 920 930
pF1KA0 LDSSRKETQTVK---EELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEK
: .. :..: .. . . ::.: : . .: .... . :. . .. .
NP_005 LRMLMRREQVLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGDAKLERLAAKFKTP-
1100 1110 1120 1130 1140 1150
940 950 960 970 980 990
pF1KA0 ERANNFEHRIEDLTRQLRNSTLQCETINSDN---EDLLARIETLQSNAKLLEVQILEVQR
: :..:....:. : : . :: :. :. : : ..:. : ... .: ..
NP_005 ELAEEFKQKFEECQRLLLDIPLQTPHKLVDTGRAAKLIQRAEEMKSGLKDFKT-FLTNDQ
1160 1170 1180 1190 1200 1210
1000 1010 1020 1030 1040 1050
pF1KA0 AKAMVDKELEAEKLQKEQKIKEHATTVN-ELEELQVQLQKEKKQLQKTMQELELVKKDAQ
.:. : .: . ::.. . :. :. .. .:.. . . .....
NP_005 TKV----TEEENKGSGTGAAGASDTTIKPNAENTGPTLEWDNYDLREDALDDSVSSSSVH
1220 1230 1240 1250 1260
1060 1070 1080 1090 1100 1110
pF1KA0 QTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQ
. : . . .. . ..... :..: .... . : . ... :. .: : :
NP_005 ASPLASSPV---RKNLFRFDESTTGSNFSFKSALSLSKSPAKLNQSGTSVGTDEESVVTQ
1270 1280 1290 1300 1310 1320
1120 1130 1140 1150 1160 1170
pF1KA0 YEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSE
::.. . . .: . :. :....... ...:.:. . .. .
NP_005 EEERDGQYFEPVVPLPDLVEVSSGEENEQVVFS-----------HRAEIYRYD-KDVGQW
1330 1340 1350 1360 1370
1180 1190 1200 1210 1220 1230
pF1KA0 KHKIHEHLKTSAEQHQRTLSAYQQRVTALQEECRAAKAEQATVTSEFESYKVRVHNVLKQ
:.. .: . .. . ..: .:. : . .: . . ..:.
NP_005 KERGIGDIKILQNYDNKQVRIVMRRDQVLKL-CANHR-----ITPD-----MSLQNMKGT
1380 1390 1400 1410 1420
1240 1250 1260 1270 1280 1290
pF1KA0 QKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQINVSELQTLQSEHDTLLERH
.. . . .... ::: . ..:::: .... .: .: : :.:.:. :
NP_005 ERVWVWTACDFADGERKVEHLAV-----RFKLQDVADSFKKIFDEAKTAQ-EKDSLITPH
1430 1440 1450 1460 1470
1300 1310 1320 1330 1340 1350
pF1KA0 NKMLQETVSKEAELREKLCSIQSENMMMKSEHTQTVSQLTSQNEVLRNSFRDQVRHLQEE
::. . ::. :. . .. : :. ... . ..: . . .: .:
NP_005 -------VSRSSTPRESPCGKIAVAIL--EETTRERTDVIQGDDVADAASEVEVSSTSET
1480 1490 1500 1510 1520
1360 1370 1380 1390
pF1KA0 HRKTV----------ETLQQQLSKMEAQLFQLKNEPTTRS--------PVSSQQSLKNLR
:.: :.... .:. ... : . : .: : :..:..: .
NP_005 TTKAVVSPPKFVFVSESVKRIFSSEKSKPFVFGNSSATGSLFGFSFNAPLKSNNSETSSV
1530 1540 1550 1560 1570 1580
1400 1410 1420 1430 1440 1450
pF1KA0 ERRNTDLPLLDMHTVTREEGEGMETTDTESVS-SASTYTQ--SLEQLLNSPETKLEPPLW
. ... . . .... ...:.. . ::: :. :.. ...:: :::::
NP_005 AQSGSESKVEPKKCELSKNSDIEQSSDSKVKNLSASFPTEESSINYTFKTPEK--EPPLW
1590 1600 1610 1620 1630 1640
1460 1470 1480 1490 1500 1510
pF1KA0 HAEFTKEELVQKLSSTTKSADHLNGLLRETEATNAILMEQIKLLKSEIRRLERNQEREKS
::::::::::::: ::::::::::::::: :::::.::::::::::::::::::::::::
NP_005 HAEFTKEELVQKLRSTTKSADHLNGLLREIEATNAVLMEQIKLLKSEIRRLERNQEREKS
1650 1660 1670 1680 1690 1700
1520 1530 1540 1550 1560 1570
pF1KA0 AANLEYLKNVLLQFIFLKPGSERERLLPVINTMLQLSPEEKGKLAAVAQGEEENASRSSG
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
NP_005 AANLEYLKNVLLQFIFLKPGSERERLLPVINTMLQLSPEEKGKLAAVAQDEEENASRSSG
1710 1720 1730 1740 1750 1760
1580
pF1KA0 WASYLHSWSGLR
1583 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 18:37:58 2016 done: Wed Nov 2 18:38:01 2016
Total Scan time: 16.260 Total Display time: 0.790
Function used was FASTA [36.3.4 Apr, 2011]