Result of FASTA (omim) for
pF1KA0330
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0330, 2220 aa
1>>>pF1KA0330 2220 - 2220 aa - 2220 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 14.9633+/-0.000498; mu= -22.7014+/- 0.031
mean_var=446.9623+/-91.319, 0's: 0 Z-trim(119.9): 49 B-trim: 551 in 1/56
Lambda= 0.060665
statistics sampled from 34533 (34584) to 34533 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.705), E-opt: 0.2 (0.405), width: 16
Scan time: 16.520
The best scores are: opt bits E(85289)
NP_036427 (OMIM: 604251) calcineurin-binding prote (2220) 14867 1317.4 0
NP_001186210 (OMIM: 604251) calcineurin-binding pr (2220) 14867 1317.4 0
XP_005261474 (OMIM: 604251) PREDICTED: calcineurin (2225) 14847 1315.7 0
XP_006724244 (OMIM: 604251) PREDICTED: calcineurin (2191) 13927 1235.2 0
NP_001188358 (OMIM: 604251) calcineurin-binding pr (2170) 13116 1164.2 0
XP_006724242 (OMIM: 604251) PREDICTED: calcineurin (2226) 9860 879.2 0
XP_016884169 (OMIM: 604251) PREDICTED: calcineurin (2221) 9858 879.0 0
XP_011528332 (OMIM: 604251) PREDICTED: calcineurin (1427) 9161 818.0 0
XP_011528331 (OMIM: 604251) PREDICTED: calcineurin (2056) 9161 818.0 0
XP_005261473 (OMIM: 604251) PREDICTED: calcineurin (2250) 9161 818.0 0
XP_005261472 (OMIM: 604251) PREDICTED: calcineurin (2255) 9161 818.0 0
XP_006724243 (OMIM: 604251) PREDICTED: calcineurin (2196) 8948 799.4 0
XP_016884171 (OMIM: 604251) PREDICTED: calcineurin (2146) 8482 758.6 1.8e-217
XP_005261476 (OMIM: 604251) PREDICTED: calcineurin (2210) 8461 756.8 6.4e-217
XP_016884170 (OMIM: 604251) PREDICTED: calcineurin (2205) 7410 664.8 3.1e-189
XP_016884172 (OMIM: 604251) PREDICTED: calcineurin (2141) 7197 646.1 1.3e-183
XP_011528328 (OMIM: 604251) PREDICTED: calcineurin (2190) 4520 411.9 4.3e-113
XP_016884173 (OMIM: 604251) PREDICTED: calcineurin (1425) 3700 340.0 1.2e-91
>>NP_036427 (OMIM: 604251) calcineurin-binding protein c (2220 aa)
initn: 14867 init1: 14867 opt: 14867 Z-score: 7045.4 bits: 1317.4 E(85289): 0
Smith-Waterman score: 14867; 100.0% identity (100.0% similar) in 2220 aa overlap (1-2220:1-2220)
10 20 30 40 50 60
pF1KA0 MIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 ELLEASLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ELLEASLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 STDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 STDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 ICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 SDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLLET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLLET
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 GAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 RLRKLDPEEEDDSFNNYEVQSEAKLESFPSIGPQRLSFDSATFMESEKQDVHEFLLENLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RLRKLDPEEEDDSFNNYEVQSEAKLESFPSIGPQRLSFDSATFMESEKQDVHEFLLENLT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 NGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 NGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 MMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFAS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 SQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSTAIQVEAGAERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSTAIQVEAGAERR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 DIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCTSG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 FDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 FDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 EEWVATVTQLLMGIEQALSADSSGSILKVSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EEWVATVTQLLMGIEQALSADSSGSILKVSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 HVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEYLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 HVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEYLG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 RRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 RYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 RPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFYMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFYMH
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 DICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 SLWIEYGTMSYALHSFASRQLKQWRGELPPELVQQMEGRRDSMLETAKHCFTSAARCEGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SLWIEYGTMSYALHSFASRQLKQWRGELPPELVQQMEGRRDSMLETAKHCFTSAARCEGD
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 GDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEA
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 LEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVD
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 EDSHSSAGTLPGPGASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQATPDDRSQDSTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EDSHSSAGTLPGPGASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQATPDDRSQDSTA
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 VALSDSSSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQGATEERGKNEESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VALSDSSSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQGATEERGKNEESL
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 ESTEGFRAAEQGVQKPAAETPASACIPGKPSASTPTLWDGKKRGDLPGEPVAFPQGLPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ESTEGFRAAEQGVQKPAAETPASACIPGKPSASTPTLWDGKKRGDLPGEPVAFPQGLPAG
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 AEEQRQFLTEQCIASFRLCLSRFPQHYKSLYRLAFLYTYSKTHRNLQWARDVLLGSSIPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 AEEQRQFLTEQCIASFRLCLSRFPQHYKSLYRLAFLYTYSKTHRNLQWARDVLLGSSIPW
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KA0 QQLQHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFAWHMNRSIVLLLKVLAQLRDHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 QQLQHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFAWHMNRSIVLLLKVLAQLRDHS
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KA0 TLLKVSSMLQRTPDQGKKYLRDADRQVLAQRAFILTVKVLEDTLSELAEGSERPGPKVCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 TLLKVSSMLQRTPDQGKKYLRDADRQVLAQRAFILTVKVLEDTLSELAEGSERPGPKVCG
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KA0 LPGARMTTDVSHKASPEDGQEGLPQPKKPPLADGSGPGPEPGGKVGLLNHRPVAMDAGDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LPGARMTTDVSHKASPEDGQEGLPQPKKPPLADGSGPGPEPGGKVGLLNHRPVAMDAGDS
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KA0 ADQSGERKDKESPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ADQSGERKDKESPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLE
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KA0 ELSISARQQPTPLTPAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ELSISARQQPTPLTPAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLL
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KA0 LDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQA
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KA0 SGDTPTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SGDTPTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCP
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KA0 PSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKM
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KA0 APTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 APTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAAS
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KA0 SKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSP
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KA0 KGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDEDDDYMDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDEDDDYMDI
2170 2180 2190 2200 2210 2220
>>NP_001186210 (OMIM: 604251) calcineurin-binding protei (2220 aa)
initn: 14867 init1: 14867 opt: 14867 Z-score: 7045.4 bits: 1317.4 E(85289): 0
Smith-Waterman score: 14867; 100.0% identity (100.0% similar) in 2220 aa overlap (1-2220:1-2220)
10 20 30 40 50 60
pF1KA0 MIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 ELLEASLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELLEASLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 STDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 ICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 SDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLLET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLLET
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 GAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 RLRKLDPEEEDDSFNNYEVQSEAKLESFPSIGPQRLSFDSATFMESEKQDVHEFLLENLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLRKLDPEEEDDSFNNYEVQSEAKLESFPSIGPQRLSFDSATFMESEKQDVHEFLLENLT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 NGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 MMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFAS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 SQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSTAIQVEAGAERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSTAIQVEAGAERR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 DIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCTSG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 FDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 EEWVATVTQLLMGIEQALSADSSGSILKVSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEWVATVTQLLMGIEQALSADSSGSILKVSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 HVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEYLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEYLG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 RRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 RYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 RPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFYMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFYMH
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 DICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 SLWIEYGTMSYALHSFASRQLKQWRGELPPELVQQMEGRRDSMLETAKHCFTSAARCEGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLWIEYGTMSYALHSFASRQLKQWRGELPPELVQQMEGRRDSMLETAKHCFTSAARCEGD
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 GDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEA
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 LEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVD
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 EDSHSSAGTLPGPGASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQATPDDRSQDSTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDSHSSAGTLPGPGASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQATPDDRSQDSTA
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 VALSDSSSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQGATEERGKNEESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VALSDSSSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQGATEERGKNEESL
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 ESTEGFRAAEQGVQKPAAETPASACIPGKPSASTPTLWDGKKRGDLPGEPVAFPQGLPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESTEGFRAAEQGVQKPAAETPASACIPGKPSASTPTLWDGKKRGDLPGEPVAFPQGLPAG
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 AEEQRQFLTEQCIASFRLCLSRFPQHYKSLYRLAFLYTYSKTHRNLQWARDVLLGSSIPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEEQRQFLTEQCIASFRLCLSRFPQHYKSLYRLAFLYTYSKTHRNLQWARDVLLGSSIPW
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KA0 QQLQHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFAWHMNRSIVLLLKVLAQLRDHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQLQHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFAWHMNRSIVLLLKVLAQLRDHS
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KA0 TLLKVSSMLQRTPDQGKKYLRDADRQVLAQRAFILTVKVLEDTLSELAEGSERPGPKVCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLLKVSSMLQRTPDQGKKYLRDADRQVLAQRAFILTVKVLEDTLSELAEGSERPGPKVCG
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KA0 LPGARMTTDVSHKASPEDGQEGLPQPKKPPLADGSGPGPEPGGKVGLLNHRPVAMDAGDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPGARMTTDVSHKASPEDGQEGLPQPKKPPLADGSGPGPEPGGKVGLLNHRPVAMDAGDS
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KA0 ADQSGERKDKESPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADQSGERKDKESPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLE
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KA0 ELSISARQQPTPLTPAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELSISARQQPTPLTPAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLL
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KA0 LDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQA
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KA0 SGDTPTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGDTPTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCP
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KA0 PSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKM
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KA0 APTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAAS
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KA0 SKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSP
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KA0 KGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDEDDDYMDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDEDDDYMDI
2170 2180 2190 2200 2210 2220
>>XP_005261474 (OMIM: 604251) PREDICTED: calcineurin-bin (2225 aa)
initn: 12742 init1: 12674 opt: 14847 Z-score: 7035.9 bits: 1315.7 E(85289): 0
Smith-Waterman score: 14847; 99.8% identity (99.8% similar) in 2225 aa overlap (1-2220:1-2225)
10 20 30 40 50 60
pF1KA0 MIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 ELLEASLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELLEASLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 STDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 ICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 SDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLLET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLLET
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 GAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 RLRKLDPEEEDDSFNNYEVQSEAKLESFPSIGPQRLSFDSATFMESEKQDVHEFLLENLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLRKLDPEEEDDSFNNYEVQSEAKLESFPSIGPQRLSFDSATFMESEKQDVHEFLLENLT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 NGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 MMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFAS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 SQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSTAIQVEAGAERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSTAIQVEAGAERR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 DIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCTSG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 FDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 EEWVATVTQLLMGIEQALSADSSGSILKVSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEWVATVTQLLMGIEQALSADSSGSILKVSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 HVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEYLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEYLG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 RRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 RYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 RPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFYMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFYMH
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 DICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 SLWIEYGTMSYALHSFASRQLKQWRGELPPELVQQMEGRRDSMLETAKHCFTSAARCEGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLWIEYGTMSYALHSFASRQLKQWRGELPPELVQQMEGRRDSMLETAKHCFTSAARCEGD
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 GDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEA
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 LEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVD
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 EDSHSSAGTLPGPGASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQATPDDRSQDSTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDSHSSAGTLPGPGASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQATPDDRSQDSTA
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 VALSDSSSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQGATEERGKNEESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VALSDSSSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQGATEERGKNEESL
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 ESTEGFRAAEQGVQKPAAETPASACIPGKPSASTPTLWDGKKRGDLPGEPVAFPQGLPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESTEGFRAAEQGVQKPAAETPASACIPGKPSASTPTLWDGKKRGDLPGEPVAFPQGLPAG
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 AEEQRQFLTEQCIASFRLCLSRFPQHYKSLYRLAFLYTYSKTHRNLQWARDVLLGSSIPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AEEQRQFLTEQCIASFRLCLSRFPQHYKSLYRLAFLYTYSKTHRNLQWARDVLLGSSIPW
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KA0 QQLQHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFAWHMNRSIVLLLKVLAQLRDHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQLQHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFAWHMNRSIVLLLKVLAQLRDHS
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KA0 TLLKVSSMLQRTPDQGKKYLRDADRQVLAQRAFILTVKVLEDTLSELAEGSERPGPKVCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLLKVSSMLQRTPDQGKKYLRDADRQVLAQRAFILTVKVLEDTLSELAEGSERPGPKVCG
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KA0 LPGARMTTDVSHKASPEDGQEGLPQPKKPPLADGSGPGPEPGGKVGLLNHRPVAMDAGDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPGARMTTDVSHKASPEDGQEGLPQPKKPPLADGSGPGPEPGGKVGLLNHRPVAMDAGDS
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KA0 ADQSGERKDKESPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ADQSGERKDKESPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLE
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KA0 ELSISARQQPTPLTPAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELSISARQQPTPLTPAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLL
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910
pF1KA0 LDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQ-----VDEEAALEQAVKFCQVHLGAA
:::::::::::::::::::::::::::::::::: :::::::::::::::::::::
XP_005 LDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQHLPVKVDEEAALEQAVKFCQVHLGAA
1870 1880 1890 1900 1910 1920
1920 1930 1940 1950 1960 1970
pF1KA0 AQRQASGDTPTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQRQASGDTPTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATT
1930 1940 1950 1960 1970 1980
1980 1990 2000 2010 2020 2030
pF1KA0 IITCPPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IITCPPSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHS
1990 2000 2010 2020 2030 2040
2040 2050 2060 2070 2080 2090
pF1KA0 PQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSP
2050 2060 2070 2080 2090 2100
2100 2110 2120 2130 2140 2150
pF1KA0 PTAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTP
2110 2120 2130 2140 2150 2160
2160 2170 2180 2190 2200 2210
pF1KA0 TLLSPKGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDEDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLLSPKGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDEDD
2170 2180 2190 2200 2210 2220
2220
pF1KA0 DYMDI
:::::
XP_005 DYMDI
>>XP_006724244 (OMIM: 604251) PREDICTED: calcineurin-bin (2191 aa)
initn: 13880 init1: 13880 opt: 13927 Z-score: 6600.9 bits: 1235.2 E(85289): 0
Smith-Waterman score: 14604; 98.7% identity (98.7% similar) in 2220 aa overlap (1-2220:1-2191)
10 20 30 40 50 60
pF1KA0 MIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 ELLEASLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELLEASLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 STDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 STDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 ICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 SDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLLET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLLET
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 GAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 RLRKLDPEEEDDSFNNYEVQSEAKLESFPSIGPQRLSFDSATFMESEKQDVHEFLLENLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLRKLDPEEEDDSFNNYEVQSEAKLESFPSIGPQRLSFDSATFMESEKQDVHEFLLENLT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 NGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 MMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFAS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 SQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSTAIQVEAGAERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSTAIQVEAGAERR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 DIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCTSG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 FDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 EEWVATVTQLLMGIEQALSADSSGSILKVSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EEWVATVTQLLMGIEQALSADSSGSILKVSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 HVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEYLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEYLG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 RRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 RYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 RPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFYMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFYMH
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 DICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 SLWIEYGTMSYALHSFASRQLKQWRGELPPELVQQMEGRRDSMLETAKHCFTSAARCEGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLWIEYGTMSYALHSFASRQLKQWRGELPPELVQQMEGRRDSMLETAKHCFTSAARCEGD
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 GDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEA
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 LEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVD
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 EDSHSSAGTLPGPGASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQATPDDRSQDSTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EDSHSSAGTLPGPGASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQATPDDRSQDSTA
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 VALSDSSSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQGATEERGKNEESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VALSDSSSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQGATEERGKNEESL
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 ESTEGFRAAEQGVQKPAAETPASACIPGKPSASTPTLWDGKKRGDLPGEPVAFPQGLPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ESTEGFRAAEQGVQKPAAETPASACIPGKPSASTPTLWDGKKRGDLPGEPVAFPQGLPAG
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 AEEQRQFLTEQCIASFRLCLSRFPQHYKSLYRLAFLYTYSKTHRNLQWARDVLLGSSIPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AEEQRQFLTEQCIASFRLCLSRFPQHYKSLYRLAFLYTYSKTHRNLQWARDVLLGSSIPW
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KA0 QQLQHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFAWHMNRSIVLLLKVLAQLRDHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QQLQHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFAWHMNRSIVLLLKVLAQLRDHS
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KA0 TLLKVSSMLQRTPDQGKKYLRDADRQVLAQRAFILTVKVLEDTLSELAEGSERPGPKVCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TLLKVSSMLQRTPDQGKKYLRDADRQVLAQRAFILTVKVLEDTLSELAEGSERPGPKVCG
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KA0 LPGARMTTDVSHKASPEDGQEGLPQPKKPPLADGSGPGPEPGGKVGLLNHRPVAMDAGDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LPGARMTTDVSHKASPEDGQEGLPQPKKPPLADGSGPGPEPGGKVGLLNHRPVAMDAGDS
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KA0 ADQSGERKDKESPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ADQSGERKDKESPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLE
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KA0 ELSISARQQPTPLTPAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELSISARQQPTPLTPAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLL
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KA0 LDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQA
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KA0 SGDTPTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SGDTPTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCP
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KA0 PSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKM
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KA0 APTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAAS
:::::::::::::::::::::::::::: :::
XP_006 APTSSPAEPHCWPAEAALGTGAEPTCSQ-----------------------------AAS
2050 2060 2070
2110 2120 2130 2140 2150 2160
pF1KA0 SKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSP
2080 2090 2100 2110 2120 2130
2170 2180 2190 2200 2210 2220
pF1KA0 KGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDEDDDYMDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDEDDDYMDI
2140 2150 2160 2170 2180 2190
>>NP_001188358 (OMIM: 604251) calcineurin-binding protei (2170 aa)
initn: 14540 init1: 13107 opt: 13116 Z-score: 6217.3 bits: 1164.2 E(85289): 0
Smith-Waterman score: 14444; 97.7% identity (97.7% similar) in 2220 aa overlap (1-2220:1-2170)
10 20 30 40 50 60
pF1KA0 MIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 ELLEASLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELLEASLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 STDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 ICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEA
:::::::::::::::::::::::::::::::::::::::
NP_001 ICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKC---------------------
190 200 210
250 260 270 280 290 300
pF1KA0 LGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDL
:::::::::::::::::::::::::::::::
NP_001 -----------------------------WKCLGESLLAMYNHLTTCEPPRPSLGKRIDL
220 230 240 250
310 320 330 340 350 360
pF1KA0 SDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLLET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLLET
260 270 280 290 300 310
370 380 390 400 410 420
pF1KA0 GAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPS
320 330 340 350 360 370
430 440 450 460 470 480
pF1KA0 RLRKLDPEEEDDSFNNYEVQSEAKLESFPSIGPQRLSFDSATFMESEKQDVHEFLLENLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLRKLDPEEEDDSFNNYEVQSEAKLESFPSIGPQRLSFDSATFMESEKQDVHEFLLENLT
380 390 400 410 420 430
490 500 510 520 530 540
pF1KA0 NGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKD
440 450 460 470 480 490
550 560 570 580 590 600
pF1KA0 MMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFAS
500 510 520 530 540 550
610 620 630 640 650 660
pF1KA0 SQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSTAIQVEAGAERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSTAIQVEAGAERR
560 570 580 590 600 610
670 680 690 700 710 720
pF1KA0 DIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCTSG
620 630 640 650 660 670
730 740 750 760 770 780
pF1KA0 FDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAK
680 690 700 710 720 730
790 800 810 820 830 840
pF1KA0 EEWVATVTQLLMGIEQALSADSSGSILKVSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEWVATVTQLLMGIEQALSADSSGSILKVSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEP
740 750 760 770 780 790
850 860 870 880 890 900
pF1KA0 HVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEYLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEYLG
800 810 820 830 840 850
910 920 930 940 950 960
pF1KA0 RRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKA
860 870 880 890 900 910
970 980 990 1000 1010 1020
pF1KA0 RYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTE
920 930 940 950 960 970
1030 1040 1050 1060 1070 1080
pF1KA0 RPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFYMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFYMH
980 990 1000 1010 1020 1030
1090 1100 1110 1120 1130 1140
pF1KA0 DICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNL
1040 1050 1060 1070 1080 1090
1150 1160 1170 1180 1190 1200
pF1KA0 SLWIEYGTMSYALHSFASRQLKQWRGELPPELVQQMEGRRDSMLETAKHCFTSAARCEGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLWIEYGTMSYALHSFASRQLKQWRGELPPELVQQMEGRRDSMLETAKHCFTSAARCEGD
1100 1110 1120 1130 1140 1150
1210 1220 1230 1240 1250 1260
pF1KA0 GDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEA
1160 1170 1180 1190 1200 1210
1270 1280 1290 1300 1310 1320
pF1KA0 LEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVD
1220 1230 1240 1250 1260 1270
1330 1340 1350 1360 1370 1380
pF1KA0 EDSHSSAGTLPGPGASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQATPDDRSQDSTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDSHSSAGTLPGPGASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQATPDDRSQDSTA
1280 1290 1300 1310 1320 1330
1390 1400 1410 1420 1430 1440
pF1KA0 VALSDSSSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQGATEERGKNEESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VALSDSSSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQGATEERGKNEESL
1340 1350 1360 1370 1380 1390
1450 1460 1470 1480 1490 1500
pF1KA0 ESTEGFRAAEQGVQKPAAETPASACIPGKPSASTPTLWDGKKRGDLPGEPVAFPQGLPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESTEGFRAAEQGVQKPAAETPASACIPGKPSASTPTLWDGKKRGDLPGEPVAFPQGLPAG
1400 1410 1420 1430 1440 1450
1510 1520 1530 1540 1550 1560
pF1KA0 AEEQRQFLTEQCIASFRLCLSRFPQHYKSLYRLAFLYTYSKTHRNLQWARDVLLGSSIPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEEQRQFLTEQCIASFRLCLSRFPQHYKSLYRLAFLYTYSKTHRNLQWARDVLLGSSIPW
1460 1470 1480 1490 1500 1510
1570 1580 1590 1600 1610 1620
pF1KA0 QQLQHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFAWHMNRSIVLLLKVLAQLRDHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQLQHMPAQGLFCERNKTNFFNGIWRIPVDEIDRPGSFAWHMNRSIVLLLKVLAQLRDHS
1520 1530 1540 1550 1560 1570
1630 1640 1650 1660 1670 1680
pF1KA0 TLLKVSSMLQRTPDQGKKYLRDADRQVLAQRAFILTVKVLEDTLSELAEGSERPGPKVCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLLKVSSMLQRTPDQGKKYLRDADRQVLAQRAFILTVKVLEDTLSELAEGSERPGPKVCG
1580 1590 1600 1610 1620 1630
1690 1700 1710 1720 1730 1740
pF1KA0 LPGARMTTDVSHKASPEDGQEGLPQPKKPPLADGSGPGPEPGGKVGLLNHRPVAMDAGDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPGARMTTDVSHKASPEDGQEGLPQPKKPPLADGSGPGPEPGGKVGLLNHRPVAMDAGDS
1640 1650 1660 1670 1680 1690
1750 1760 1770 1780 1790 1800
pF1KA0 ADQSGERKDKESPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADQSGERKDKESPRAGPTEPMDTSEATVCHSDLERTPPLLPGRPARDRGPESRPTELSLE
1700 1710 1720 1730 1740 1750
1810 1820 1830 1840 1850 1860
pF1KA0 ELSISARQQPTPLTPAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELSISARQQPTPLTPAQPAPAPAPATTTGTRAGGHPEEPLSRLSRKRKLLEDTESGKTLL
1760 1770 1780 1790 1800 1810
1870 1880 1890 1900 1910 1920
pF1KA0 LDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDAYRVWQQGQKGVAYDLGRVERIMSETYMLIKQVDEEAALEQAVKFCQVHLGAAAQRQA
1820 1830 1840 1850 1860 1870
1930 1940 1950 1960 1970 1980
pF1KA0 SGDTPTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGDTPTTPKHPKDSRENFFPVTVVPTAPDPVPADSVQRPSDAHTKPRPALAAATTIITCP
1880 1890 1900 1910 1920 1930
1990 2000 2010 2020 2030 2040
pF1KA0 PSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSASASTLDQSKDPGPPRPHRPEATPSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKM
1940 1950 1960 1970 1980 1990
2050 2060 2070 2080 2090 2100
pF1KA0 APTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APTSSPAEPHCWPAEAALGTGAEPTCSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAAS
2000 2010 2020 2030 2040 2050
2110 2120 2130 2140 2150 2160
pF1KA0 SKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKAPSSGSAQPPEGHPGKPEPSRAKSRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSP
2060 2070 2080 2090 2100 2110
2170 2180 2190 2200 2210 2220
pF1KA0 KGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDEDDDYMDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGSISEETKQKLKSAILSAQSAANVRKESLCQPALEVLETSSQESSLESETDEDDDYMDI
2120 2130 2140 2150 2160 2170
>>XP_006724242 (OMIM: 604251) PREDICTED: calcineurin-bin (2226 aa)
initn: 13442 init1: 9161 opt: 9860 Z-score: 4677.0 bits: 879.2 E(85289): 0
Smith-Waterman score: 14514; 97.2% identity (97.2% similar) in 2255 aa overlap (1-2220:1-2226)
10 20 30 40 50 60
pF1KA0 MIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 ELLEASLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELLEASLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 STDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 STDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 ICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 SDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLLET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLLET
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 GAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 RLRKLDPEEEDDSFNNYEVQSEAKLESFPSIGPQRLSFDSATFMESEKQDVHEFLLENLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLRKLDPEEEDDSFNNYEVQSEAKLESFPSIGPQRLSFDSATFMESEKQDVHEFLLENLT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 NGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 MMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFAS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 SQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSTAIQVEAGAERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSTAIQVEAGAERR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 DIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCTSG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 FDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 EEWVATVTQLLMGIEQALSADSSGSILKVSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EEWVATVTQLLMGIEQALSADSSGSILKVSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 HVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEYLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEYLG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 RRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 RYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 RPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFYMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFYMH
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 DICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 SLWIEYGTMSYALHSFASRQLKQWRGELPPELVQQMEGRRDSMLETAKHCFTSAARCEGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLWIEYGTMSYALHSFASRQLKQWRGELPPELVQQMEGRRDSMLETAKHCFTSAARCEGD
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 GDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEA
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 LEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVD
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370
pF1KA0 EDSHSSAGTLPGPGASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQATPD--------
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EDSHSSAGTLPGPGASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQATPDGTVPVLPT
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410
pF1KA0 ----------------------DRSQDSTAVALSDSSSTQDFFNEPTSLLEGSRKSYTEK
::::::::::::::::::::::::::::::::::::::
XP_006 ASPGRHINHGGVLGRLILSLRFDRSQDSTAVALSDSSSTQDFFNEPTSLLEGSRKSYTEK
1390 1400 1410 1420 1430 1440
1420 1430 1440 1450 1460 1470
pF1KA0 RLPILSSQAGATGKDLQGATEERGKNEESLESTEGFRAAEQGVQKPAAETPASACIPGKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLPILSSQAGATGKDLQGATEERGKNEESLESTEGFRAAEQGVQKPAAETPASACIPGKP
1450 1460 1470 1480 1490 1500
1480 1490 1500 1510 1520 1530
pF1KA0 SASTPTLWDGKKRGDLPGEPVAFPQGLPAGAEEQRQFLTEQCIASFRLCLSRFPQHYKSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SASTPTLWDGKKRGDLPGEPVAFPQGLPAGAEEQRQFLTEQCIASFRLCLSRFPQHYKSL
1510 1520 1530 1540 1550 1560
1540 1550 1560 1570 1580 1590
pF1KA0 YRLAFLYTYSKTHRNLQWARDVLLGSSIPWQQLQHMPAQGLFCERNKTNFFNGIWRIPVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YRLAFLYTYSKTHRNLQWARDVLLGSSIPWQQLQHMPAQGLFCERNKTNFFNGIWRIPVD
1570 1580 1590 1600 1610 1620
1600 1610 1620 1630 1640 1650
pF1KA0 EIDRPGSFAWHMNRSIVLLLKVLAQLRDHSTLLKVSSMLQRTPDQGKKYLRDADRQVLAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EIDRPGSFAWHMNRSIVLLLKVLAQLRDHSTLLKVSSMLQRTPDQGKKYLRDADRQVLAQ
1630 1640 1650 1660 1670 1680
1660 1670 1680 1690 1700 1710
pF1KA0 RAFILTVKVLEDTLSELAEGSERPGPKVCGLPGARMTTDVSHKASPEDGQEGLPQPKKPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RAFILTVKVLEDTLSELAEGSERPGPKVCGLPGARMTTDVSHKASPEDGQEGLPQPKKPP
1690 1700 1710 1720 1730 1740
1720 1730 1740 1750 1760 1770
pF1KA0 LADGSGPGPEPGGKVGLLNHRPVAMDAGDSADQSGERKDKESPRAGPTEPMDTSEATVCH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LADGSGPGPEPGGKVGLLNHRPVAMDAGDSADQSGERKDKESPRAGPTEPMDTSEATVCH
1750 1760 1770 1780 1790 1800
1780 1790 1800 1810 1820 1830
pF1KA0 SDLERTPPLLPGRPARDRGPESRPTELSLEELSISARQQPTPLTPAQPAPAPAPATTTGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SDLERTPPLLPGRPARDRGPESRPTELSLEELSISARQQPTPLTPAQPAPAPAPATTTGT
1810 1820 1830 1840 1850 1860
1840 1850 1860 1870 1880 1890
pF1KA0 RAGGHPEEPLSRLSRKRKLLEDTESGKTLLLDAYRVWQQGQKGVAYDLGRVERIMSETYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RAGGHPEEPLSRLSRKRKLLEDTESGKTLLLDAYRVWQQGQKGVAYDLGRVERIMSETYM
1870 1880 1890 1900 1910 1920
1900 1910 1920 1930 1940
pF1KA0 LIKQ-----VDEEAALEQAVKFCQVHLGAAAQRQASGDTPTTPKHPKDSRENFFPVTVVP
:::: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LIKQHLPVKVDEEAALEQAVKFCQVHLGAAAQRQASGDTPTTPKHPKDSRENFFPVTVVP
1930 1940 1950 1960 1970 1980
1950 1960 1970 1980 1990 2000
pF1KA0 TAPDPVPADSVQRPSDAHTKPRPALAAATTIITCPPSASASTLDQSKDPGPPRPHRPEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TAPDPVPADSVQRPSDAHTKPRPALAAATTIITCPPSASASTLDQSKDPGPPRPHRPEAT
1990 2000 2010 2020 2030 2040
2010 2020 2030 2040 2050 2060
pF1KA0 PSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPT
2050 2060 2070 2080 2090 2100
2070 2080 2090 2100 2110 2120
pF1KA0 CSQEGKLRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSSGSAQPPEGHPGKPEPSRAK
::: ::::::::::::::::::::::::::::
XP_006 CSQ-----------------------------AASSKAPSSGSAQPPEGHPGKPEPSRAK
2110 2120 2130
2130 2140 2150 2160 2170 2180
pF1KA0 SRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAANV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SRPLPNMPKLVIPSAATKFPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAANV
2140 2150 2160 2170 2180 2190
2190 2200 2210 2220
pF1KA0 RKESLCQPALEVLETSSQESSLESETDEDDDYMDI
:::::::::::::::::::::::::::::::::::
XP_006 RKESLCQPALEVLETSSQESSLESETDEDDDYMDI
2200 2210 2220
>>XP_016884169 (OMIM: 604251) PREDICTED: calcineurin-bin (2221 aa)
initn: 13866 init1: 9161 opt: 9858 Z-score: 4676.1 bits: 879.0 E(85289): 0
Smith-Waterman score: 14534; 97.4% identity (97.4% similar) in 2250 aa overlap (1-2220:1-2221)
10 20 30 40 50 60
pF1KA0 MIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 ELLEASLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELLEASLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 STDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 ICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 SDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLLET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLLET
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 GAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 RLRKLDPEEEDDSFNNYEVQSEAKLESFPSIGPQRLSFDSATFMESEKQDVHEFLLENLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLRKLDPEEEDDSFNNYEVQSEAKLESFPSIGPQRLSFDSATFMESEKQDVHEFLLENLT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 NGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 MMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFAS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 SQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSTAIQVEAGAERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSTAIQVEAGAERR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 DIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCTSG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 FDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 EEWVATVTQLLMGIEQALSADSSGSILKVSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEWVATVTQLLMGIEQALSADSSGSILKVSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 HVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEYLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEYLG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 RRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 RYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 RPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFYMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFYMH
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 DICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 SLWIEYGTMSYALHSFASRQLKQWRGELPPELVQQMEGRRDSMLETAKHCFTSAARCEGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLWIEYGTMSYALHSFASRQLKQWRGELPPELVQQMEGRRDSMLETAKHCFTSAARCEGD
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 GDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEA
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 LEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVD
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370
pF1KA0 EDSHSSAGTLPGPGASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQATPD--------
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDSHSSAGTLPGPGASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQATPDGTVPVLPT
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410
pF1KA0 ----------------------DRSQDSTAVALSDSSSTQDFFNEPTSLLEGSRKSYTEK
::::::::::::::::::::::::::::::::::::::
XP_016 ASPGRHINHGGVLGRLILSLRFDRSQDSTAVALSDSSSTQDFFNEPTSLLEGSRKSYTEK
1390 1400 1410 1420 1430 1440
1420 1430 1440 1450 1460 1470
pF1KA0 RLPILSSQAGATGKDLQGATEERGKNEESLESTEGFRAAEQGVQKPAAETPASACIPGKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLPILSSQAGATGKDLQGATEERGKNEESLESTEGFRAAEQGVQKPAAETPASACIPGKP
1450 1460 1470 1480 1490 1500
1480 1490 1500 1510 1520 1530
pF1KA0 SASTPTLWDGKKRGDLPGEPVAFPQGLPAGAEEQRQFLTEQCIASFRLCLSRFPQHYKSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SASTPTLWDGKKRGDLPGEPVAFPQGLPAGAEEQRQFLTEQCIASFRLCLSRFPQHYKSL
1510 1520 1530 1540 1550 1560
1540 1550 1560 1570 1580 1590
pF1KA0 YRLAFLYTYSKTHRNLQWARDVLLGSSIPWQQLQHMPAQGLFCERNKTNFFNGIWRIPVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YRLAFLYTYSKTHRNLQWARDVLLGSSIPWQQLQHMPAQGLFCERNKTNFFNGIWRIPVD
1570 1580 1590 1600 1610 1620
1600 1610 1620 1630 1640 1650
pF1KA0 EIDRPGSFAWHMNRSIVLLLKVLAQLRDHSTLLKVSSMLQRTPDQGKKYLRDADRQVLAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIDRPGSFAWHMNRSIVLLLKVLAQLRDHSTLLKVSSMLQRTPDQGKKYLRDADRQVLAQ
1630 1640 1650 1660 1670 1680
1660 1670 1680 1690 1700 1710
pF1KA0 RAFILTVKVLEDTLSELAEGSERPGPKVCGLPGARMTTDVSHKASPEDGQEGLPQPKKPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAFILTVKVLEDTLSELAEGSERPGPKVCGLPGARMTTDVSHKASPEDGQEGLPQPKKPP
1690 1700 1710 1720 1730 1740
1720 1730 1740 1750 1760 1770
pF1KA0 LADGSGPGPEPGGKVGLLNHRPVAMDAGDSADQSGERKDKESPRAGPTEPMDTSEATVCH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LADGSGPGPEPGGKVGLLNHRPVAMDAGDSADQSGERKDKESPRAGPTEPMDTSEATVCH
1750 1760 1770 1780 1790 1800
1780 1790 1800 1810 1820 1830
pF1KA0 SDLERTPPLLPGRPARDRGPESRPTELSLEELSISARQQPTPLTPAQPAPAPAPATTTGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDLERTPPLLPGRPARDRGPESRPTELSLEELSISARQQPTPLTPAQPAPAPAPATTTGT
1810 1820 1830 1840 1850 1860
1840 1850 1860 1870 1880 1890
pF1KA0 RAGGHPEEPLSRLSRKRKLLEDTESGKTLLLDAYRVWQQGQKGVAYDLGRVERIMSETYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAGGHPEEPLSRLSRKRKLLEDTESGKTLLLDAYRVWQQGQKGVAYDLGRVERIMSETYM
1870 1880 1890 1900 1910 1920
1900 1910 1920 1930 1940 1950
pF1KA0 LIKQVDEEAALEQAVKFCQVHLGAAAQRQASGDTPTTPKHPKDSRENFFPVTVVPTAPDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIKQVDEEAALEQAVKFCQVHLGAAAQRQASGDTPTTPKHPKDSRENFFPVTVVPTAPDP
1930 1940 1950 1960 1970 1980
1960 1970 1980 1990 2000 2010
pF1KA0 VPADSVQRPSDAHTKPRPALAAATTIITCPPSASASTLDQSKDPGPPRPHRPEATPSMAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPADSVQRPSDAHTKPRPALAAATTIITCPPSASASTLDQSKDPGPPRPHRPEATPSMAS
1990 2000 2010 2020 2030 2040
2020 2030 2040 2050 2060 2070
pF1KA0 LGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQ--
2050 2060 2070 2080 2090
2080 2090 2100 2110 2120 2130
pF1KA0 KLRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLP
:::::::::::::::::::::::::::::::::
XP_016 ---------------------------AASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLP
2100 2110 2120 2130
2140 2150 2160 2170 2180 2190
pF1KA0 NMPKLVIPSAATKFPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAANVRKESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NMPKLVIPSAATKFPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAANVRKESL
2140 2150 2160 2170 2180 2190
2200 2210 2220
pF1KA0 CQPALEVLETSSQESSLESETDEDDDYMDI
::::::::::::::::::::::::::::::
XP_016 CQPALEVLETSSQESSLESETDEDDDYMDI
2200 2210 2220
>>XP_011528332 (OMIM: 604251) PREDICTED: calcineurin-bin (1427 aa)
initn: 9161 init1: 9161 opt: 9161 Z-score: 4349.6 bits: 818.0 E(85289): 0
Smith-Waterman score: 9161; 100.0% identity (100.0% similar) in 1372 aa overlap (1-1372:1-1372)
10 20 30 40 50 60
pF1KA0 MIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 ELLEASLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELLEASLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 STDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 ICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 SDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLLET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLLET
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 GAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 RLRKLDPEEEDDSFNNYEVQSEAKLESFPSIGPQRLSFDSATFMESEKQDVHEFLLENLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLRKLDPEEEDDSFNNYEVQSEAKLESFPSIGPQRLSFDSATFMESEKQDVHEFLLENLT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 NGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 MMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFAS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 SQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSTAIQVEAGAERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSTAIQVEAGAERR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 DIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCTSG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 FDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 EEWVATVTQLLMGIEQALSADSSGSILKVSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEWVATVTQLLMGIEQALSADSSGSILKVSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 HVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEYLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEYLG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 RRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 RYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 RPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFYMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFYMH
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 DICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 SLWIEYGTMSYALHSFASRQLKQWRGELPPELVQQMEGRRDSMLETAKHCFTSAARCEGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLWIEYGTMSYALHSFASRQLKQWRGELPPELVQQMEGRRDSMLETAKHCFTSAARCEGD
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 GDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEA
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 LEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVD
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 EDSHSSAGTLPGPGASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQATPDDRSQDSTA
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDSHSSAGTLPGPGASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQATPDGFVFLLAP
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 VALSDSSSTQDFFNEPTSLLEGSRKSYTEKRLPILSSQAGATGKDLQGATEERGKNEESL
XP_011 VTARFREQRRPACSALSPAPCYPCDQEHLHVCSPCDLESVFDALGFC
1390 1400 1410 1420
>>XP_011528331 (OMIM: 604251) PREDICTED: calcineurin-bin (2056 aa)
initn: 12728 init1: 9161 opt: 9161 Z-score: 4347.0 bits: 818.0 E(85289): 0
Smith-Waterman score: 13398; 98.3% identity (98.3% similar) in 2048 aa overlap (1-2013:1-2048)
10 20 30 40 50 60
pF1KA0 MIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 ELLEASLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELLEASLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 STDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 ICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 SDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLLET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLLET
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 GAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 RLRKLDPEEEDDSFNNYEVQSEAKLESFPSIGPQRLSFDSATFMESEKQDVHEFLLENLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLRKLDPEEEDDSFNNYEVQSEAKLESFPSIGPQRLSFDSATFMESEKQDVHEFLLENLT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 NGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 MMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFAS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 SQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSTAIQVEAGAERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSTAIQVEAGAERR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 DIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCTSG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 FDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 EEWVATVTQLLMGIEQALSADSSGSILKVSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEWVATVTQLLMGIEQALSADSSGSILKVSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 HVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEYLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEYLG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 RRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 RYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 RPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFYMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFYMH
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 DICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 SLWIEYGTMSYALHSFASRQLKQWRGELPPELVQQMEGRRDSMLETAKHCFTSAARCEGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLWIEYGTMSYALHSFASRQLKQWRGELPPELVQQMEGRRDSMLETAKHCFTSAARCEGD
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 GDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEA
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 LEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVD
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370
pF1KA0 EDSHSSAGTLPGPGASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQATPD--------
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDSHSSAGTLPGPGASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQATPDGTVPVLPT
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410
pF1KA0 ----------------------DRSQDSTAVALSDSSSTQDFFNEPTSLLEGSRKSYTEK
::::::::::::::::::::::::::::::::::::::
XP_011 ASPGRHINHGGVLGRLILSLRFDRSQDSTAVALSDSSSTQDFFNEPTSLLEGSRKSYTEK
1390 1400 1410 1420 1430 1440
1420 1430 1440 1450 1460 1470
pF1KA0 RLPILSSQAGATGKDLQGATEERGKNEESLESTEGFRAAEQGVQKPAAETPASACIPGKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLPILSSQAGATGKDLQGATEERGKNEESLESTEGFRAAEQGVQKPAAETPASACIPGKP
1450 1460 1470 1480 1490 1500
1480 1490 1500 1510 1520 1530
pF1KA0 SASTPTLWDGKKRGDLPGEPVAFPQGLPAGAEEQRQFLTEQCIASFRLCLSRFPQHYKSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SASTPTLWDGKKRGDLPGEPVAFPQGLPAGAEEQRQFLTEQCIASFRLCLSRFPQHYKSL
1510 1520 1530 1540 1550 1560
1540 1550 1560 1570 1580 1590
pF1KA0 YRLAFLYTYSKTHRNLQWARDVLLGSSIPWQQLQHMPAQGLFCERNKTNFFNGIWRIPVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRLAFLYTYSKTHRNLQWARDVLLGSSIPWQQLQHMPAQGLFCERNKTNFFNGIWRIPVD
1570 1580 1590 1600 1610 1620
1600 1610 1620 1630 1640 1650
pF1KA0 EIDRPGSFAWHMNRSIVLLLKVLAQLRDHSTLLKVSSMLQRTPDQGKKYLRDADRQVLAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIDRPGSFAWHMNRSIVLLLKVLAQLRDHSTLLKVSSMLQRTPDQGKKYLRDADRQVLAQ
1630 1640 1650 1660 1670 1680
1660 1670 1680 1690 1700 1710
pF1KA0 RAFILTVKVLEDTLSELAEGSERPGPKVCGLPGARMTTDVSHKASPEDGQEGLPQPKKPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAFILTVKVLEDTLSELAEGSERPGPKVCGLPGARMTTDVSHKASPEDGQEGLPQPKKPP
1690 1700 1710 1720 1730 1740
1720 1730 1740 1750 1760 1770
pF1KA0 LADGSGPGPEPGGKVGLLNHRPVAMDAGDSADQSGERKDKESPRAGPTEPMDTSEATVCH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LADGSGPGPEPGGKVGLLNHRPVAMDAGDSADQSGERKDKESPRAGPTEPMDTSEATVCH
1750 1760 1770 1780 1790 1800
1780 1790 1800 1810 1820 1830
pF1KA0 SDLERTPPLLPGRPARDRGPESRPTELSLEELSISARQQPTPLTPAQPAPAPAPATTTGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDLERTPPLLPGRPARDRGPESRPTELSLEELSISARQQPTPLTPAQPAPAPAPATTTGT
1810 1820 1830 1840 1850 1860
1840 1850 1860 1870 1880 1890
pF1KA0 RAGGHPEEPLSRLSRKRKLLEDTESGKTLLLDAYRVWQQGQKGVAYDLGRVERIMSETYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAGGHPEEPLSRLSRKRKLLEDTESGKTLLLDAYRVWQQGQKGVAYDLGRVERIMSETYM
1870 1880 1890 1900 1910 1920
1900 1910 1920 1930 1940
pF1KA0 LIKQ-----VDEEAALEQAVKFCQVHLGAAAQRQASGDTPTTPKHPKDSRENFFPVTVVP
:::: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIKQHLPVKVDEEAALEQAVKFCQVHLGAAAQRQASGDTPTTPKHPKDSRENFFPVTVVP
1930 1940 1950 1960 1970 1980
1950 1960 1970 1980 1990 2000
pF1KA0 TAPDPVPADSVQRPSDAHTKPRPALAAATTIITCPPSASASTLDQSKDPGPPRPHRPEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAPDPVPADSVQRPSDAHTKPRPALAAATTIITCPPSASASTLDQSKDPGPPRPHRPEAT
1990 2000 2010 2020 2030 2040
2010 2020 2030 2040 2050 2060
pF1KA0 PSMASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPT
::::::::
XP_011 PSMASLGPVSCIKWIR
2050
>>XP_005261473 (OMIM: 604251) PREDICTED: calcineurin-bin (2250 aa)
initn: 14853 init1: 9161 opt: 9161 Z-score: 4346.3 bits: 818.0 E(85289): 0
Smith-Waterman score: 14797; 98.7% identity (98.7% similar) in 2250 aa overlap (1-2220:1-2250)
10 20 30 40 50 60
pF1KA0 MIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MIRIAALNASSTIEDDHEGSFKSHKTQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 ELLEASLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELLEASLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 STDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STDVNLWYKIGHVALRLIRIPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 ICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYNHLTTCEPPRPSLGKRIDL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 SDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLLET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDYQDPSQPLESSMVVTPVNVIQPSTVSTNPAVAVAEPVVSYTSVATTSFPLHSPGLLET
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 GAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GAPVGDISGGDKSKKGVKRKKISEESGETAKRRSARVRNTKCKKEEKVDFQELLMKFLPS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 RLRKLDPEEEDDSFNNYEVQSEAKLESFPSIGPQRLSFDSATFMESEKQDVHEFLLENLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLRKLDPEEEDDSFNNYEVQSEAKLESFPSIGPQRLSFDSATFMESEKQDVHEFLLENLT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 NGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NGGILELMMRYLKAMGHKFLVRWPPGLAEVVLSVYHSWRRHSTSLPNPLLRDCSNKHIKD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 MMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MMLMSLSCMELQLDQWLLTKGRSSAVSPRNCPAGMVNGRFGPDFPGTHCLGDLLQLSFAS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 SQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSTAIQVEAGAERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQRDLFEDGWLEFVVRVYWLKARFLALQGDMEQALENYDICTEMLQSSTAIQVEAGAERR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 DIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DIVIRLPNLHNDSVVSLEEIDKNLKSLERCQSLEEIQRLYEAGDYKAVVHLLRPTLCTSG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 FDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FDRAKHLEFMTSIPERPAQLLLLQDSLLRLKDYRQCFECSDVALNEAVQQMVNSGEAAAK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 EEWVATVTQLLMGIEQALSADSSGSILKVSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEWVATVTQLLMGIEQALSADSSGSILKVSSSTTGLVRLTNNLIQVIDCSMAVQEEAKEP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 HVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEYLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HVSSVLPWIILHRIIWQEEDTFHSLCHQQQLQNPAEEGMSETPMLPSSLMLLNTAHEYLG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 RRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RRSWCCNSDGALLRFYVRVLQKELAASTSEDTHPYKEELETALEQCFYCLYSFPSKKSKA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 RYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RYLEEHSAQQVDLIWEDALFMFEYFKPKTLPEFDSYKTSTVSADLANLLKRIATIVPRTE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 RPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFYMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RPALSLDKVSAYIEGTSTEVPCLPEGADPSPPVVNELYYLLADYHFKNKEQSKAIKFYMH
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 DICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DICICPNRFDSWAGMALARASRIQDKLNSNELKSDGPIWKHATPVLNCFRRALEIDSSNL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 SLWIEYGTMSYALHSFASRQLKQWRGELPPELVQQMEGRRDSMLETAKHCFTSAARCEGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLWIEYGTMSYALHSFASRQLKQWRGELPPELVQQMEGRRDSMLETAKHCFTSAARCEGD
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 GDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GDEEEWLIHYMLGKVAEKQQQPPTVYLLHYRQAGHYLHEEAARYPKKIHYHNPPELAMEA
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 LEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEVYFRLHASILKLLGKPDSGVGAEVLVNFMKEAAEGPFARGEEKNTPKASEKEKACLVD
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370
pF1KA0 EDSHSSAGTLPGPGASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQATPD--------
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDSHSSAGTLPGPGASLPSSSGPGLTSPPYTATPIDHDYVKCKKPHQQATPDGTVPVLPT
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410
pF1KA0 ----------------------DRSQDSTAVALSDSSSTQDFFNEPTSLLEGSRKSYTEK
::::::::::::::::::::::::::::::::::::::
XP_005 ASPGRHINHGGVLGRLILSLRFDRSQDSTAVALSDSSSTQDFFNEPTSLLEGSRKSYTEK
1390 1400 1410 1420 1430 1440
1420 1430 1440 1450 1460 1470
pF1KA0 RLPILSSQAGATGKDLQGATEERGKNEESLESTEGFRAAEQGVQKPAAETPASACIPGKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLPILSSQAGATGKDLQGATEERGKNEESLESTEGFRAAEQGVQKPAAETPASACIPGKP
1450 1460 1470 1480 1490 1500
1480 1490 1500 1510 1520 1530
pF1KA0 SASTPTLWDGKKRGDLPGEPVAFPQGLPAGAEEQRQFLTEQCIASFRLCLSRFPQHYKSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SASTPTLWDGKKRGDLPGEPVAFPQGLPAGAEEQRQFLTEQCIASFRLCLSRFPQHYKSL
1510 1520 1530 1540 1550 1560
1540 1550 1560 1570 1580 1590
pF1KA0 YRLAFLYTYSKTHRNLQWARDVLLGSSIPWQQLQHMPAQGLFCERNKTNFFNGIWRIPVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YRLAFLYTYSKTHRNLQWARDVLLGSSIPWQQLQHMPAQGLFCERNKTNFFNGIWRIPVD
1570 1580 1590 1600 1610 1620
1600 1610 1620 1630 1640 1650
pF1KA0 EIDRPGSFAWHMNRSIVLLLKVLAQLRDHSTLLKVSSMLQRTPDQGKKYLRDADRQVLAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EIDRPGSFAWHMNRSIVLLLKVLAQLRDHSTLLKVSSMLQRTPDQGKKYLRDADRQVLAQ
1630 1640 1650 1660 1670 1680
1660 1670 1680 1690 1700 1710
pF1KA0 RAFILTVKVLEDTLSELAEGSERPGPKVCGLPGARMTTDVSHKASPEDGQEGLPQPKKPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RAFILTVKVLEDTLSELAEGSERPGPKVCGLPGARMTTDVSHKASPEDGQEGLPQPKKPP
1690 1700 1710 1720 1730 1740
1720 1730 1740 1750 1760 1770
pF1KA0 LADGSGPGPEPGGKVGLLNHRPVAMDAGDSADQSGERKDKESPRAGPTEPMDTSEATVCH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LADGSGPGPEPGGKVGLLNHRPVAMDAGDSADQSGERKDKESPRAGPTEPMDTSEATVCH
1750 1760 1770 1780 1790 1800
1780 1790 1800 1810 1820 1830
pF1KA0 SDLERTPPLLPGRPARDRGPESRPTELSLEELSISARQQPTPLTPAQPAPAPAPATTTGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDLERTPPLLPGRPARDRGPESRPTELSLEELSISARQQPTPLTPAQPAPAPAPATTTGT
1810 1820 1830 1840 1850 1860
1840 1850 1860 1870 1880 1890
pF1KA0 RAGGHPEEPLSRLSRKRKLLEDTESGKTLLLDAYRVWQQGQKGVAYDLGRVERIMSETYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RAGGHPEEPLSRLSRKRKLLEDTESGKTLLLDAYRVWQQGQKGVAYDLGRVERIMSETYM
1870 1880 1890 1900 1910 1920
1900 1910 1920 1930 1940 1950
pF1KA0 LIKQVDEEAALEQAVKFCQVHLGAAAQRQASGDTPTTPKHPKDSRENFFPVTVVPTAPDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIKQVDEEAALEQAVKFCQVHLGAAAQRQASGDTPTTPKHPKDSRENFFPVTVVPTAPDP
1930 1940 1950 1960 1970 1980
1960 1970 1980 1990 2000 2010
pF1KA0 VPADSVQRPSDAHTKPRPALAAATTIITCPPSASASTLDQSKDPGPPRPHRPEATPSMAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VPADSVQRPSDAHTKPRPALAAATTIITCPPSASASTLDQSKDPGPPRPHRPEATPSMAS
1990 2000 2010 2020 2030 2040
2020 2030 2040 2050 2060 2070
pF1KA0 LGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALGTGAEPTCSQEG
2050 2060 2070 2080 2090 2100
2080 2090 2100 2110 2120 2130
pF1KA0 KLRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLRPEPRRDGEAQEAASETQPLSSPPTAASSKAPSSGSAQPPEGHPGKPEPSRAKSRPLP
2110 2120 2130 2140 2150 2160
2140 2150 2160 2170 2180 2190
pF1KA0 NMPKLVIPSAATKFPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAANVRKESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NMPKLVIPSAATKFPPEITVTPPTPTLLSPKGSISEETKQKLKSAILSAQSAANVRKESL
2170 2180 2190 2200 2210 2220
2200 2210 2220
pF1KA0 CQPALEVLETSSQESSLESETDEDDDYMDI
::::::::::::::::::::::::::::::
XP_005 CQPALEVLETSSQESSLESETDEDDDYMDI
2230 2240 2250
2220 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 18:37:06 2016 done: Wed Nov 2 18:37:09 2016
Total Scan time: 16.520 Total Display time: 1.670
Function used was FASTA [36.3.4 Apr, 2011]