Result of FASTA (omim) for
pF1KA0246
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0246, 2570 aa
1>>>pF1KA0246 2570 - 2570 aa - 2570 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.5360+/-0.000561; mu= 16.1552+/- 0.035
mean_var=222.5750+/-44.880, 0's: 0 Z-trim(115.8): 554 B-trim: 295 in 2/48
Lambda= 0.085968
statistics sampled from 25827 (26508) to 25827 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.635), E-opt: 0.2 (0.311), width: 16
Scan time: 24.640
The best scores are: opt bits E(85289)
NP_055951 (OMIM: 608560) stabilin-1 precursor [Hom (2570) 18695 2334.5 0
XP_005265031 (OMIM: 608560) PREDICTED: stabilin-1 (2569) 18676 2332.1 0
XP_005265030 (OMIM: 608560) PREDICTED: stabilin-1 (2595) 17754 2217.8 0
XP_016861491 (OMIM: 608560) PREDICTED: stabilin-1 (2565) 12613 1580.2 0
XP_016861493 (OMIM: 608560) PREDICTED: stabilin-1 (1819) 11775 1476.1 0
XP_016861492 (OMIM: 608560) PREDICTED: stabilin-1 (2555) 11775 1476.2 0
XP_016861489 (OMIM: 608560) PREDICTED: stabilin-1 (2589) 11775 1476.2 0
XP_016861488 (OMIM: 608560) PREDICTED: stabilin-1 (2590) 11775 1476.2 0
XP_016861487 (OMIM: 608560) PREDICTED: stabilin-1 (2615) 11775 1476.2 0
XP_006713128 (OMIM: 608560) PREDICTED: stabilin-1 (1619) 11682 1464.5 0
XP_016861490 (OMIM: 608560) PREDICTED: stabilin-1 (2583) 7211 910.2 0
XP_011536840 (OMIM: 608561) PREDICTED: stabilin-2 (2242) 3820 489.5 2.1e-136
XP_016875074 (OMIM: 608561) PREDICTED: stabilin-2 (2246) 3820 489.5 2.1e-136
XP_011536839 (OMIM: 608561) PREDICTED: stabilin-2 (2283) 3820 489.5 2.1e-136
NP_060034 (OMIM: 608561) stabilin-2 precursor [Hom (2551) 3820 489.6 2.3e-136
XP_011536841 (OMIM: 608561) PREDICTED: stabilin-2 (1994) 3472 446.3 1.9e-123
XP_011536843 (OMIM: 608561) PREDICTED: stabilin-2 (1684) 2550 331.9 4.6e-89
XP_011536844 (OMIM: 608561) PREDICTED: stabilin-2 (1238) 2014 265.2 3.9e-69
NP_000129 (OMIM: 102370,129600,134797,154700,18490 (2871) 530 81.6 1.7e-13
XP_016882868 (OMIM: 608529) PREDICTED: fibrillin-3 (2851) 516 79.9 5.6e-13
XP_016882865 (OMIM: 608529) PREDICTED: fibrillin-3 (2766) 498 77.6 2.6e-12
XP_016882864 (OMIM: 608529) PREDICTED: fibrillin-3 (2768) 498 77.6 2.6e-12
XP_016882862 (OMIM: 608529) PREDICTED: fibrillin-3 (2789) 498 77.6 2.6e-12
XP_016882861 (OMIM: 608529) PREDICTED: fibrillin-3 (2809) 498 77.6 2.6e-12
NP_001308360 (OMIM: 608529) fibrillin-3 precursor (2809) 498 77.6 2.6e-12
NP_115823 (OMIM: 608529) fibrillin-3 precursor [Ho (2809) 498 77.6 2.6e-12
XP_011539189 (OMIM: 604266) PREDICTED: multiple ep (1395) 490 76.3 3.3e-12
XP_006710469 (OMIM: 604266) PREDICTED: multiple ep (1436) 490 76.3 3.4e-12
NP_001400 (OMIM: 604266) multiple epidermal growth (1541) 490 76.3 3.5e-12
XP_016856022 (OMIM: 604266) PREDICTED: multiple ep (1559) 490 76.4 3.5e-12
XP_011539187 (OMIM: 604266) PREDICTED: multiple ep (1603) 490 76.4 3.6e-12
XP_016882863 (OMIM: 608529) PREDICTED: fibrillin-3 (2777) 473 74.5 2.2e-11
XP_016878164 (OMIM: 612454) PREDICTED: multiple ep ( 854) 464 72.8 2.2e-11
XP_016878163 (OMIM: 612454) PREDICTED: multiple ep ( 854) 464 72.8 2.2e-11
NP_000618 (OMIM: 150390) latent-transforming growt (1395) 465 73.2 2.8e-11
NP_001159738 (OMIM: 150390) latent-transforming gr (1300) 464 73.0 2.9e-11
NP_001159736 (OMIM: 150390) latent-transforming gr (1353) 464 73.1 3e-11
NP_996826 (OMIM: 150390) latent-transforming growt (1721) 465 73.3 3.2e-11
XP_011531155 (OMIM: 150390) PREDICTED: latent-tran (1722) 465 73.3 3.2e-11
XP_011539188 (OMIM: 604266) PREDICTED: multiple ep (1560) 464 73.1 3.3e-11
XP_005264375 (OMIM: 150390) PREDICTED: latent-tran (1626) 464 73.1 3.4e-11
XP_016859598 (OMIM: 150390) PREDICTED: latent-tran (1679) 464 73.2 3.5e-11
XP_011531159 (OMIM: 150390) PREDICTED: latent-tran (1680) 464 73.2 3.5e-11
XP_011541996 (OMIM: 612453,614399) PREDICTED: mult (1140) 436 69.5 3e-10
NP_115822 (OMIM: 612453,614399) multiple epidermal (1140) 436 69.5 3e-10
NP_001243474 (OMIM: 612453,614399) multiple epider (1140) 436 69.5 3e-10
XP_016865476 (OMIM: 612453,614399) PREDICTED: mult (1195) 436 69.5 3.1e-10
XP_011507814 (OMIM: 610278) PREDICTED: platelet en ( 868) 432 68.9 3.6e-10
XP_016859599 (OMIM: 150390) PREDICTED: latent-tran (1639) 436 69.7 3.8e-10
XP_016856724 (OMIM: 610278) PREDICTED: platelet en (1081) 432 69.0 4.1e-10
>>NP_055951 (OMIM: 608560) stabilin-1 precursor [Homo sa (2570 aa)
initn: 18695 init1: 18695 opt: 18695 Z-score: 12539.7 bits: 2334.5 E(85289): 0
Smith-Waterman score: 18695; 99.9% identity (100.0% similar) in 2570 aa overlap (1-2570:1-2570)
10 20 30 40 50 60
pF1KA0 MAGPRGLLPLCLLAFCLAGFSFVRGQVLFKGCDVKTTFVTHVPCTSCAAIKKQTCPSGWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MAGPRGLLPLCLLAFCLAGFSFVRGQVLFKGCDVKTTFVTHVPCTSCAAIKKQTCPSGWL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 RELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCHECPGGAETPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCHECPGGAETPC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 NGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 CLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 CSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 TCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVGDGRACYGHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVGDGRACYGHLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 HEVQKATQTGRVFLQLRVAVAMMDQGCREILTTAGPFTVLVPSVSSFSSRTMNASLAQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 HEVQKATQTGRVFLQLRVAVAMMDQGCREILTTAGPFTVLVPSVSSFSSRTMNASLAQQL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 CRQHIIAGQHILEDTRTQQTRRWWTLAGQEITVTFNQFTKYSYKYKDQPQQTFNIYKANN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CRQHIIAGQHILEDTRTQQTRRWWTLAGQEITVTFNQFTKYSYKYKDQPQQTFNIYKANN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 IAANGVFHVVTGLRWQAPSGTPGDPKRTIGQILASTEAFSRFETILENCGLPSILDGPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IAANGVFHVVTGLRWQAPSGTPGDPKRTIGQILASTEAFSRFETILENCGLPSILDGPGP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 FTVFAPSNEAVDSLRDGRLIYLFTAGLSKLQELVRYHIYNHGQLTVEKLISKGRILTMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FTVFAPSNEAVDSLRDGRLIYLFTAGLSKLQELVRYHIYNHGQLTVEKLISKGRILTMAN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 QVLAVNISEEGRILLGPEGVPLQRVDVMAANGVIHMLDGILLPPTILPILPKHCSEEQHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QVLAVNISEEGRILLGPEGVPLQRVDVMAANGVIHMLDGILLPPTILPILPKHCSEEQHK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 IVAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IVAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGC
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 CKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQC
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 QEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 EGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 VCVAIDECELDVRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHG
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LATCRAVGGGQRVCTCPPGFGGDGFSCYGDIFRELEANAHFSIFYQWLKSAGITLPADRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LATCRAVGGGQRVCTCPPGFGGDGFSCYGDIFRELEANAHFSIFYQWLKSAGITLPADRR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 VTALVPSEAAVRQLSPEDRAFWLQPRTLPNLVRAHFLQGALFEEELARLGGQEVATLNPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VTALVPSEAAVRQLSPEDRAFWLQPRTLPNLVRAHFLQGALFEEELARLGGQEVATLNPT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 TRWEIRNISGRVWVQNASVDVADLLATNGVLHILSQVLLPPRGDVPGGQGLLQQLDLVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TRWEIRNISGRVWVQNASVDVADLLATNGVLHILSQVLLPPRGDVPGGQGLLQQLDLVPA
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 FSLFRELLQHHGLVPQIEAATAYTIFVPTNRSLEAQGNSSHLDADTVRHHVVLGEALSME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FSLFRELLQHHGLVPQIEAATAYTIFVPTNRSLEAQGNSSHLDADTVRHHVVLGEALSME
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 TLRKGGHRNSLLGPAHWIVFYNHSGQPEVNHVPLEGPMLEAPGRSLIGLSGVLTVGSSRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TLRKGGHRNSLLGPAHWIVFYNHSGQPEVNHVPLEGPMLEAPGRSLIGLSGVLTVGSSRC
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 LHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDC
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 CPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCT
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 GVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTC
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 ACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINS
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 CLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKST
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KA0 GDGQRTCTCDTAHTVGDGLTCRARVGLELLRDKHASFFSLRLLEYKELKGDGPFTIFVPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GDGQRTCTCDTAHTVGDGLTCRARVGLELLRDKHASFFSLRLLEYKELKGDGPFTIFVPH
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KA0 ADLMSNLSQDELARIRAHRQLVFRYHVVGCRRLRSEDLLEQGYATALSGHPLRFSEREGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ADLMSNLSQDELARIRAHRQLVFRYHVVGCRRLRSEDLLEQGYATALSGHPLRFSEREGS
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KA0 IYLNDFARVVSSDHEAVNGILHFIDRVLLPPEALHWEPDDAPIPRRNVTAAAQGFGYKIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IYLNDFARVVSSDHEAVNGILHFIDRVLLPPEALHWEPDDAPIPRRNVTAAAQGFGYKIF
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KA0 SGLLKVAGLLPLLREASHRPFTMLWPTDAAFRALPPDRQAWLYHEDHRDKLAAILRGHMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SGLLKVAGLLPLLREASHRPFTMLWPTDAAFRALPPDRQAWLYHEDHRDKLAAILRGHMI
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KA0 RNVEALASDLPNLGPLRTMHGTPISFSCSRTRPGELMVGEDDARIVQRHLPFEGGLAYGI
:::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
NP_055 RNVEALASDLPNLGPLRTMHGTPISFSCSRTRAGELMVGEDDARIVQRHLPFEGGLAYGI
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KA0 DQLLEPPGLGARCDHFETRPLRLNTCSICGLEPPCPEGSQEQGSPEACWRFYPKFWTSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DQLLEPPGLGARCDHFETRPLRLNTCSICGLEPPCPEGSQEQGSPEACWRFYPKFWTSPP
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KA0 LHSLGLRSVWVHPSLWGRPQGLGRGCHRNCVTTTWKPSCCPGHYGSECQACPGGPSSPCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LHSLGLRSVWVHPSLWGRPQGLGRGCHRNCVTTTWKPSCCPGHYGSECQACPGGPSSPCS
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KA0 DRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCF
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KA0 CDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSLGYEGDGRVCTVADLCQDGHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSLGYEGDGRVCTVADLCQDGHG
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KA0 GCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRC
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KA0 ECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTDLHFQEKRAGVFHLQATSGPYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTDLHFQEKRAGVFHLQATSGPYG
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KA0 LNFSEAEAACEAQGAVLASFPQLSAAQQLGFHLCLMGWLANGSTAHPVVFPVADCGNGRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LNFSEAEAACEAQGAVLASFPQLSAAQQLGFHLCLMGWLANGSTAHPVVFPVADCGNGRV
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KA0 GIVSLGARKNLSERWDAYCFRVQDVACRCRNGFVGDGISTCNGKLLDVLAATANFSTFYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GIVSLGARKNLSERWDAYCFRVQDVACRCRNGFVGDGISTCNGKLLDVLAATANFSTFYG
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KA0 MLLGYANATQRGLDFLDFLDDELTYKTLFVPVNEGFVDNMTLSGPDLELHASNATLLSAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MLLGYANATQRGLDFLDFLDDELTYKTLFVPVNEGFVDNMTLSGPDLELHASNATLLSAN
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KA0 ASQGKLLPAHSGLSLIISDAGPDNSSWAPVAPGTVVVSRIIVWDIMAFNGIIHALASPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ASQGKLLPAHSGLSLIISDAGPDNSSWAPVAPGTVVVSRIIVWDIMAFNGIIHALASPLL
2410 2420 2430 2440 2450 2460
2470 2480 2490 2500 2510 2520
pF1KA0 APPQPQAVLAPEAPPVAAGVGAVLAAGALLGLVAGALYLRARGKPMGFGFSAFQAEDDAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 APPQPQAVLAPEAPPVAAGVGAVLAAGALLGLVAGALYLRARGKPMGFGFSAFQAEDDAD
2470 2480 2490 2500 2510 2520
2530 2540 2550 2560 2570
pF1KA0 DDFSPWQEGTNPTLVSVPNPVFGSDTFCEPFDDSLLEEDFPDTQRILTVK
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DDFSPWQEGTNPTLVSVPNPVFGSDTFCEPFDDSLLEEDFPDTQRILTVK
2530 2540 2550 2560 2570
>>XP_005265031 (OMIM: 608560) PREDICTED: stabilin-1 isof (2569 aa)
initn: 17993 init1: 17993 opt: 18676 Z-score: 12526.9 bits: 2332.1 E(85289): 0
Smith-Waterman score: 18676; 99.9% identity (99.9% similar) in 2570 aa overlap (1-2570:1-2569)
10 20 30 40 50 60
pF1KA0 MAGPRGLLPLCLLAFCLAGFSFVRGQVLFKGCDVKTTFVTHVPCTSCAAIKKQTCPSGWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAGPRGLLPLCLLAFCLAGFSFVRGQVLFKGCDVKTTFVTHVPCTSCAAIKKQTCPSGWL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 RELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCHECPGGAETPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCHECPGGAETPC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 NGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 CLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 CSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 TCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVGDGRACYGHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVGDGRACYGHLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 HEVQKATQTGRVFLQLRVAVAMMDQGCREILTTAGPFTVLVPSVSSFSSRTMNASLAQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HEVQKATQTGRVFLQLRVAVAMMDQGCREILTTAGPFTVLVPSVSSFSSRTMNASLAQQL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 CRQHIIAGQHILEDTRTQQTRRWWTLAGQEITVTFNQFTKYSYKYKDQPQQTFNIYKANN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CRQHIIAGQHILEDTRTQQTRRWWTLAGQEITVTFNQFTKYSYKYKDQPQQTFNIYKANN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 IAANGVFHVVTGLRWQAPSGTPGDPKRTIGQILASTEAFSRFETILENCGLPSILDGPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IAANGVFHVVTGLRWQAPSGTPGDPKRTIGQILASTEAFSRFETILENCGLPSILDGPGP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 FTVFAPSNEAVDSLRDGRLIYLFTAGLSKLQELVRYHIYNHGQLTVEKLISKGRILTMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FTVFAPSNEAVDSLRDGRLIYLFTAGLSKLQELVRYHIYNHGQLTVEKLISKGRILTMAN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 QVLAVNISEEGRILLGPEGVPLQRVDVMAANGVIHMLDGILLPPTILPILPKHCSEEQHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QVLAVNISEEGRILLGPEGVPLQRVDVMAANGVIHMLDGILLPPTILPILPKHCSEEQHK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 IVAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IVAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGC
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 CKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQC
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 QEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 EGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 VCVAIDECELDVRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHG
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LATCRAVGGGQRVCTCPPGFGGDGFSCYGDIFRELEANAHFSIFYQWLKSAGITLPADRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LATCRAVGGGQRVCTCPPGFGGDGFSCYGDIFRELEANAHFSIFYQWLKSAGITLPADRR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 VTALVPSEAAVRQLSPEDRAFWLQPRTLPNLVRAHFLQGALFEEELARLGGQEVATLNPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTALVPSEAAVRQLSPEDRAFWLQPRTLPNLVRAHFLQGALFEEELARLGGQEVATLNPT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 TRWEIRNISGRVWVQNASVDVADLLATNGVLHILSQVLLPPRGDVPGGQGLLQQLDLVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TRWEIRNISGRVWVQNASVDVADLLATNGVLHILSQVLLPPRGDVPGGQGLLQQLDLVPA
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 FSLFRELLQHHGLVPQIEAATAYTIFVPTNRSLEAQGNSSHLDADTVRHHVVLGEALSME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FSLFRELLQHHGLVPQIEAATAYTIFVPTNRSLEAQGNSSHLDADTVRHHVVLGEALSME
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 TLRKGGHRNSLLGPAHWIVFYNHSGQPEVNHVPLEGPMLEAPGRSLIGLSGVLTVGSSRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLRKGGHRNSLLGPAHWIVFYNHSGQPEVNHVPLEGPMLEAPGRSLIGLSGVLTVGSSRC
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 LHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDC
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 CPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCT
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 GVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTC
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 ACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINS
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 CLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKST
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KA0 GDGQRTCTCDTAHTVGDGLTCRARVGLELLRDKHASFFSLRLLEYKELKGDGPFTIFVPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GDGQRTCTCDTAHTVGDGLTCRARVGLELLRDKHASFFSLRLLEYKELKGDGPFTIFVPH
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KA0 ADLMSNLSQDELARIRAHRQLVFRYHVVGCRRLRSEDLLEQGYATALSGHPLRFSEREGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ADLMSNLSQDELARIRAHRQLVFRYHVVGCRRLRSEDLLEQGYATALSGHPLRFSEREGS
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KA0 IYLNDFARVVSSDHEAVNGILHFIDRVLLPPEALHWEPDDAPIPRRNVTAAAQGFGYKIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IYLNDFARVVSSDHEAVNGILHFIDRVLLPPEALHWEPDDAPIPRRNVTAAAQGFGYKIF
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KA0 SGLLKVAGLLPLLREASHRPFTMLWPTDAAFRALPPDRQAWLYHEDHRDKLAAILRGHMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGLLKVAGLLPLLREASHRPFTMLWPTDAAFRALPPDRQAWLYHEDHRDKLAAILRGHMI
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KA0 RNVEALASDLPNLGPLRTMHGTPISFSCSRTRPGELMVGEDDARIVQRHLPFEGGLAYGI
:::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
XP_005 RNVEALASDLPNLGPLRTMHGTPISFSCSRTRAGELMVGEDDARIVQRHLPFEGGLAYGI
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KA0 DQLLEPPGLGARCDHFETRPLRLNTCSICGLEPPCPEGSQEQGSPEACWRFYPKFWTSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DQLLEPPGLGARCDHFETRPLRLNTCSICGLEPPCPEGSQEQGSPEACWRFYPKFWTSPP
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KA0 LHSLGLRSVWVHPSLWGRPQGLGRGCHRNCVTTTWKPSCCPGHYGSECQACPGGPSSPCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHSLGLRSVWVHPSLWGRPQGLGRGCHRNCVTTTWKPSCCPGHYGSECQACPGGPSSPCS
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KA0 DRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCF
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KA0 CDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSLGYEGDGRVCTVADLCQDGHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSLGYEGDGRVCTVADLCQDGHG
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KA0 GCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRC
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KA0 ECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTDLHFQEKRAGVFHLQATSGPYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTDLHFQEKRAGVFHLQATSGPYG
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KA0 LNFSEAEAACEAQGAVLASFPQLSAAQQLGFHLCLMGWLANGSTAHPVVFPVADCGNGRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNFSEAEAACEAQGAVLASFPQLSAAQQLGFHLCLMGWLANGSTAHPVVFPVADCGNGRV
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KA0 GIVSLGARKNLSERWDAYCFRVQDVACRCRNGFVGDGISTCNGKLLDVLAATANFSTFYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GIVSLGARKNLSERWDAYCFRVQDVACRCRNGFVGDGISTCNGKLLDVLAATANFSTFYG
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KA0 MLLGYANATQRGLDFLDFLDDELTYKTLFVPVNEGFVDNMTLSGPDLELHASNATLLSAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLLGYANATQRGLDFLDFLDDELTYKTLFVPVNEGFVDNMTLSGPDLELHASNATLLSAN
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KA0 ASQGKLLPAHSGLSLIISDAGPDNSSWAPVAPGTVVVSRIIVWDIMAFNGIIHALASPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASQGKLLPAHSGLSLIISDAGPDNSSWAPVAPGTVVVSRIIVWDIMAFNGIIHALASPLL
2410 2420 2430 2440 2450 2460
2470 2480 2490 2500 2510 2520
pF1KA0 APPQPQAVLAPEAPPVAAGVGAVLAAGALLGLVAGALYLRARGKPMGFGFSAFQAEDDAD
::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 APPQP-AVLAPEAPPVAAGVGAVLAAGALLGLVAGALYLRARGKPMGFGFSAFQAEDDAD
2470 2480 2490 2500 2510
2530 2540 2550 2560 2570
pF1KA0 DDFSPWQEGTNPTLVSVPNPVFGSDTFCEPFDDSLLEEDFPDTQRILTVK
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DDFSPWQEGTNPTLVSVPNPVFGSDTFCEPFDDSLLEEDFPDTQRILTVK
2520 2530 2540 2550 2560
>>XP_005265030 (OMIM: 608560) PREDICTED: stabilin-1 isof (2595 aa)
initn: 18681 init1: 17752 opt: 17754 Z-score: 11908.9 bits: 2217.8 E(85289): 0
Smith-Waterman score: 18635; 99.0% identity (99.0% similar) in 2595 aa overlap (1-2570:1-2595)
10 20 30 40 50 60
pF1KA0 MAGPRGLLPLCLLAFCLAGFSFVRGQVLFKGCDVKTTFVTHVPCTSCAAIKKQTCPSGWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAGPRGLLPLCLLAFCLAGFSFVRGQVLFKGCDVKTTFVTHVPCTSCAAIKKQTCPSGWL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 RELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCHECPGGAETPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCHECPGGAETPC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 NGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 CLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 CSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 TCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVGDGRACYGHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVGDGRACYGHLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 HEVQKATQTGRVFLQLRVAVAMMDQGCREILTTAGPFTVLVPSVSSFSSRTMNASLAQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HEVQKATQTGRVFLQLRVAVAMMDQGCREILTTAGPFTVLVPSVSSFSSRTMNASLAQQL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 CRQHIIAGQHILEDTRTQQTRRWWTLAGQEITVTFNQFTKYSYKYKDQPQQTFNIYKANN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CRQHIIAGQHILEDTRTQQTRRWWTLAGQEITVTFNQFTKYSYKYKDQPQQTFNIYKANN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 IAANGVFHVVTGLRWQAPSGTPGDPKRTIGQILASTEAFSRFETILENCGLPSILDGPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IAANGVFHVVTGLRWQAPSGTPGDPKRTIGQILASTEAFSRFETILENCGLPSILDGPGP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 FTVFAPSNEAVDSLRDGRLIYLFTAGLSKLQELVRYHIYNHGQLTVEKLISKGRILTMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FTVFAPSNEAVDSLRDGRLIYLFTAGLSKLQELVRYHIYNHGQLTVEKLISKGRILTMAN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 QVLAVNISEEGRILLGPEGVPLQRVDVMAANGVIHMLDGILLPPTILPILPKHCSEEQHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QVLAVNISEEGRILLGPEGVPLQRVDVMAANGVIHMLDGILLPPTILPILPKHCSEEQHK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 IVAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IVAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGC
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 CKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQC
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 QEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 EGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 VCVAIDECELDVRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHG
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LATCRAVGGGQRVCTCPPGFGGDGFSCYGDIFRELEANAHFSIFYQWLKSAGITLPADRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LATCRAVGGGQRVCTCPPGFGGDGFSCYGDIFRELEANAHFSIFYQWLKSAGITLPADRR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 VTALVPSEAAVRQLSPEDRAFWLQPRTLPNLVRAHFLQGALFEEELARLGGQEVATLNPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTALVPSEAAVRQLSPEDRAFWLQPRTLPNLVRAHFLQGALFEEELARLGGQEVATLNPT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 TRWEIRNISGRVWVQNASVDVADLLATNGVLHILSQVLLPPRGDVPGGQGLLQQLDLVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TRWEIRNISGRVWVQNASVDVADLLATNGVLHILSQVLLPPRGDVPGGQGLLQQLDLVPA
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 FSLFRELLQHHGLVPQIEAATAYTIFVPTNRSLEAQGNSSHLDADTVRHHVVLGEALSME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FSLFRELLQHHGLVPQIEAATAYTIFVPTNRSLEAQGNSSHLDADTVRHHVVLGEALSME
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 TLRKGGHRNSLLGPAHWIVFYNHSGQPEVNHVPLEGPMLEAPGRSLIGLSGVLTVGSSRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLRKGGHRNSLLGPAHWIVFYNHSGQPEVNHVPLEGPMLEAPGRSLIGLSGVLTVGSSRC
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 LHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDC
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 CPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCT
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 GVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTC
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 ACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINS
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 CLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKST
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KA0 GDGQRTCTCDTAHTVGDGLTCRARVGLELLRDKHASFFSLRLLEYKELKGDGPFTIFVPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GDGQRTCTCDTAHTVGDGLTCRARVGLELLRDKHASFFSLRLLEYKELKGDGPFTIFVPH
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KA0 ADLMSNLSQDELARIRAHRQLVFRYHVVGCRRLRSEDLLEQGYATALSGHPLRFSEREGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ADLMSNLSQDELARIRAHRQLVFRYHVVGCRRLRSEDLLEQGYATALSGHPLRFSEREGS
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KA0 IYLNDFARVVSSDHEAVNGILHFIDRVLLPPEALHWEPDDAPIPRRNVTAAAQGFGYKIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IYLNDFARVVSSDHEAVNGILHFIDRVLLPPEALHWEPDDAPIPRRNVTAAAQGFGYKIF
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KA0 SGLLKVAGLLPLLREASHRPFTMLWPTDAAFRALPPDRQAWLYHEDHRDKLAAILRGHMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGLLKVAGLLPLLREASHRPFTMLWPTDAAFRALPPDRQAWLYHEDHRDKLAAILRGHMI
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KA0 RNVEALASDLPNLGPLRTMHGTPISFSCSRTRPGELMVGEDDARIVQRHLPFEGGLAYGI
:::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
XP_005 RNVEALASDLPNLGPLRTMHGTPISFSCSRTRAGELMVGEDDARIVQRHLPFEGGLAYGI
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KA0 DQLLEPPGLGARCDHFETRPLRLNTCSICGLEPPCPEGSQEQGSPEACWRFYPKFWTSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DQLLEPPGLGARCDHFETRPLRLNTCSICGLEPPCPEGSQEQGSPEACWRFYPKFWTSPP
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KA0 LHSLGLRSVWVHPSLWGRPQGLGRGCHRNCVTTTWKPSCCPGHYGSECQACPGGPSSPCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHSLGLRSVWVHPSLWGRPQGLGRGCHRNCVTTTWKPSCCPGHYGSECQACPGGPSSPCS
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KA0 DRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCF
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KA0 CDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSLGYEGDGRVCTVADLCQDGHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSLGYEGDGRVCTVADLCQDGHG
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KA0 GCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRC
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KA0 ECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTDLHFQEKRAGVFHLQATSGPYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTDLHFQEKRAGVFHLQATSGPYG
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KA0 LNFSEAEAACEAQGAVLASFPQLSAAQQLGFHLCLMGWLANGSTAHPVVFPVADCGNGRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNFSEAEAACEAQGAVLASFPQLSAAQQLGFHLCLMGWLANGSTAHPVVFPVADCGNGRV
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KA0 GIVSLGARKNLSERWDAYCFRVQDVACRCRNGFVGDGISTCNGKLLDVLAATANFSTFYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GIVSLGARKNLSERWDAYCFRVQDVACRCRNGFVGDGISTCNGKLLDVLAATANFSTFYG
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KA0 MLLGYANATQRGLDFLDFLDDELTYKTLFVPVNEGFVDNMTLSGPDLELHASNATLLSAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLLGYANATQRGLDFLDFLDDELTYKTLFVPVNEGFVDNMTLSGPDLELHASNATLLSAN
2350 2360 2370 2380 2390 2400
2410 2420 2430
pF1KA0 ASQGKLLPAHSGLSLIISDAGPDNSSWAPV-------------------------APGTV
:::::::::::::::::::::::::::::: :::::
XP_005 ASQGKLLPAHSGLSLIISDAGPDNSSWAPVVSLATVPPCWPWPSLTVGLTLVSLQAPGTV
2410 2420 2430 2440 2450 2460
2440 2450 2460 2470 2480 2490
pF1KA0 VVSRIIVWDIMAFNGIIHALASPLLAPPQPQAVLAPEAPPVAAGVGAVLAAGALLGLVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVSRIIVWDIMAFNGIIHALASPLLAPPQPQAVLAPEAPPVAAGVGAVLAAGALLGLVAG
2470 2480 2490 2500 2510 2520
2500 2510 2520 2530 2540 2550
pF1KA0 ALYLRARGKPMGFGFSAFQAEDDADDDFSPWQEGTNPTLVSVPNPVFGSDTFCEPFDDSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALYLRARGKPMGFGFSAFQAEDDADDDFSPWQEGTNPTLVSVPNPVFGSDTFCEPFDDSL
2530 2540 2550 2560 2570 2580
2560 2570
pF1KA0 LEEDFPDTQRILTVK
:::::::::::::::
XP_005 LEEDFPDTQRILTVK
2590
>>XP_016861491 (OMIM: 608560) PREDICTED: stabilin-1 isof (2565 aa)
initn: 15725 init1: 11775 opt: 12613 Z-score: 8463.0 bits: 1580.2 E(85289): 0
Smith-Waterman score: 18076; 96.3% identity (96.3% similar) in 2615 aa overlap (1-2570:1-2565)
10 20 30 40 50 60
pF1KA0 MAGPRGLLPLCLLAFCLAGFSFVRGQVLFKGCDVKTTFVTHVPCTSCAAIKKQTCPSGWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGPRGLLPLCLLAFCLAGFSFVRGQVLFKGCDVKTTFVTHVPCTSCAAIKKQTCPSGWL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 RELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCHECPGGAETPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCHECPGGAETPC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 NGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 CLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 CSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 TCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVGDGRACYGHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVGDGRACYGHLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 HEVQKATQTGRVFLQLRVAVAMMDQGCREILTTAGPFTVLVPSVSSFSSRTMNASLAQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEVQKATQTGRVFLQLRVAVAMMDQGCREILTTAGPFTVLVPSVSSFSSRTMNASLAQQL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 CRQHIIAGQHILEDTRTQQTRRWWTLAGQEITVTFNQFTKYSYKYKDQPQQTFNIYKANN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRQHIIAGQHILEDTRTQQTRRWWTLAGQEITVTFNQFTKYSYKYKDQPQQTFNIYKANN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 IAANGVFHVVTGLRWQAPSGTPGDPKRTIGQILASTEAFSRFETILENCGLPSILDGPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAANGVFHVVTGLRWQAPSGTPGDPKRTIGQILASTEAFSRFETILENCGLPSILDGPGP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 FTVFAPSNEAVDSLRDGRLIYLFTAGLSKLQELVRYHIYNHGQLTVEKLISKGRILTMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTVFAPSNEAVDSLRDGRLIYLFTAGLSKLQELVRYHIYNHGQLTVEKLISKGRILTMAN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 QVLAVNISEEGRILLGPEGVPLQRVDVMAANGVIHMLDGILLPPTILPILPKHCSEEQHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVLAVNISEEGRILLGPEGVPLQRVDVMAANGVIHMLDGILLPPTILPILPKHCSEEQHK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 IVAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGC
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 CKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQC
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 QEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 EGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 VCVAIDECELDVRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHG
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LATCRAVGGGQRVCTCPPGFGGDGFSCYGDIFRELEANAHFSIFYQWLKSAGITLPADRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LATCRAVGGGQRVCTCPPGFGGDGFSCYGDIFRELEANAHFSIFYQWLKSAGITLPADRR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 VTALVPSEAAVRQLSPEDRAFWLQPRTLPNLVRAHFLQGALFEEELARLGGQEVATLNPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTALVPSEAAVRQLSPEDRAFWLQPRTLPNLVRAHFLQGALFEEELARLGGQEVATLNPT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 TRWEIRNISGRVWVQNASVDVADLLATNGVLHILSQVLLPPRGDVPGGQGLLQQLDLVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRWEIRNISGRVWVQNASVDVADLLATNGVLHILSQVLLPPRGDVPGGQGLLQQLDLVPA
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 FSLFRELLQHHGLVPQIEAATAYTIFVPTNRSLEAQGNSSHLDADTVRHHVVLGEALSME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSLFRELLQHHGLVPQIEAATAYTIFVPTNRSLEAQGNSSHLDADTVRHHVVLGEALSME
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 TLRKGGHRNSLLGPAHWIVFYNHSGQPEVNHVPLEGPMLEAPGRSLIGLSGVLTVGSSRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLRKGGHRNSLLGPAHWIVFYNHSGQPEVNHVPLEGPMLEAPGRSLIGLSGVLTVGSSRC
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 LHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDC
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 CPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCT
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 GVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTC
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 ACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINS
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 CLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKST
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600
pF1KA0 GDGQRTCTCDTAHTVGDGLTCRARVGLELLRDKHASFFSLRLLE----------------
::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDGQRTCTCDTAHTVGDGLTCRARVGLELLRDKHASFFSLRLLEIHGRLRLLPFHSCCCC
1570 1580 1590 1600 1610 1620
1610 1620 1630 1640 1650 1660
pF1KA0 ----YKELKGDGPFTIFVPHADLMSNLSQDELARIRAHRQLVFRYHVVGCRRLRSEDLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPQEYKELKGDGPFTIFVPHADLMSNLSQDELARIRAHRQLVFRYHVVGCRRLRSEDLLE
1630 1640 1650 1660 1670 1680
1670 1680 1690 1700 1710 1720
pF1KA0 QGYATALSGHPLRFSEREGSIYLNDFARVVSSDHEAVNGILHFIDRVLLPPEALHWEPDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGYATALSGHPLRFSEREGSIYLNDFARVVSSDHEAVNGILHFIDRVLLPPEALHWEPDD
1690 1700 1710 1720 1730 1740
1730 1740 1750 1760 1770 1780
pF1KA0 APIPRRNVTAAAQGFGYKIFSGLLKVAGLLPLLREASHRPFTMLWPTDAAFRALPPDRQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APIPRRNVTAAAQGFGYKIFSGLLKVAGLLPLLREASHRPFTMLWPTDAAFRALPPDRQA
1750 1760 1770 1780 1790 1800
1790 1800 1810 1820 1830 1840
pF1KA0 WLYHEDHRDKLAAILRGHMIRNVEALASDLPNLGPLRTMHGTPISFSCSRTRPGELMVGE
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_016 WLYHEDHRDKLAAILRGHMIRNVEALASDLPNLGPLRTMHGTPISFSCSRTRAGELMVGE
1810 1820 1830 1840 1850 1860
1850 1860 1870 1880 1890 1900
pF1KA0 DDARIVQRHLPFEGGLAYGIDQLLEPPGLGARCDHFETRPLRLNTCSICGLEPPCPEGSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDARIVQRHLPFEGGLAYGIDQLLEPPGLGARCDHFETRPLRLNTCSICGLEPPCPEGSQ
1870 1880 1890 1900 1910 1920
1910 1920 1930 1940 1950 1960
pF1KA0 EQGSPEACWRFYPKFWTSPPLHSLGLRSVWVHPSLWGRPQGLGRGCHRNCVTTTWKPSCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQGSPEACWRFYPKFWTSPPLHSLGLRSVWVHPSLWGRPQGLGRGCHRNCVTTTWKPSCC
1930 1940 1950 1960 1970 1980
1970 1980 1990 2000 2010 2020
pF1KA0 PGHYGSECQACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQA
:::::::::::
XP_016 PGHYGSECQAC-------------------------------------------------
1990
2030 2040 2050 2060 2070 2080
pF1KA0 CRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 -RCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSL
2000 2010 2020 2030 2040 2050
2090 2100 2110 2120 2130 2140
pF1KA0 GYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGH
2060 2070 2080 2090 2100 2110
2150 2160 2170 2180 2190 2200
pF1KA0 RGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTDL
2120 2130 2140 2150 2160 2170
2210 2220 2230 2240 2250 2260
pF1KA0 HFQEKRAGVFHLQATSGPYGLNFSEAEAACEAQGAVLASFPQLSAAQQLGFHLCLMGWLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HFQEKRAGVFHLQATSGPYGLNFSEAEAACEAQGAVLASFPQLSAAQQLGFHLCLMGWLA
2180 2190 2200 2210 2220 2230
2270 2280 2290 2300 2310 2320
pF1KA0 NGSTAHPVVFPVADCGNGRVGIVSLGARKNLSERWDAYCFRVQDVACRCRNGFVGDGIST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGSTAHPVVFPVADCGNGRVGIVSLGARKNLSERWDAYCFRVQDVACRCRNGFVGDGIST
2240 2250 2260 2270 2280 2290
2330 2340 2350 2360 2370 2380
pF1KA0 CNGKLLDVLAATANFSTFYGMLLGYANATQRGLDFLDFLDDELTYKTLFVPVNEGFVDNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CNGKLLDVLAATANFSTFYGMLLGYANATQRGLDFLDFLDDELTYKTLFVPVNEGFVDNM
2300 2310 2320 2330 2340 2350
2390 2400 2410 2420 2430
pF1KA0 TLSGPDLELHASNATLLSANASQGKLLPAHSGLSLIISDAGPDNSSWAPV----------
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLSGPDLELHASNATLLSANASQGKLLPAHSGLSLIISDAGPDNSSWAPVVSLATVPPCW
2360 2370 2380 2390 2400 2410
2440 2450 2460 2470
pF1KA0 ---------------APGTVVVSRIIVWDIMAFNGIIHALASPLLAPPQPQAVLAPEAPP
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 PWPSLTVGLTLVSLQAPGTVVVSRIIVWDIMAFNGIIHALASPLLAPPQPQAVLAPEAPP
2420 2430 2440 2450 2460 2470
2480 2490 2500 2510 2520 2530
pF1KA0 VAAGVGAVLAAGALLGLVAGALYLRARGKPMGFGFSAFQAEDDADDDFSPWQEGTNPTLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAAGVGAVLAAGALLGLVAGALYLRARGKPMGFGFSAFQAEDDADDDFSPWQEGTNPTLV
2480 2490 2500 2510 2520 2530
2540 2550 2560 2570
pF1KA0 SVPNPVFGSDTFCEPFDDSLLEEDFPDTQRILTVK
:::::::::::::::::::::::::::::::::::
XP_016 SVPNPVFGSDTFCEPFDDSLLEEDFPDTQRILTVK
2540 2550 2560
>>XP_016861493 (OMIM: 608560) PREDICTED: stabilin-1 isof (1819 aa)
initn: 11775 init1: 11775 opt: 11775 Z-score: 7903.0 bits: 1476.1 E(85289): 0
Smith-Waterman score: 12687; 98.7% identity (98.8% similar) in 1771 aa overlap (1-1751:1-1769)
10 20 30 40 50 60
pF1KA0 MAGPRGLLPLCLLAFCLAGFSFVRGQVLFKGCDVKTTFVTHVPCTSCAAIKKQTCPSGWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGPRGLLPLCLLAFCLAGFSFVRGQVLFKGCDVKTTFVTHVPCTSCAAIKKQTCPSGWL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 RELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCHECPGGAETPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCHECPGGAETPC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 NGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 CLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 CSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 TCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVGDGRACYGHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVGDGRACYGHLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 HEVQKATQTGRVFLQLRVAVAMMDQGCREILTTAGPFTVLVPSVSSFSSRTMNASLAQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEVQKATQTGRVFLQLRVAVAMMDQGCREILTTAGPFTVLVPSVSSFSSRTMNASLAQQL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 CRQHIIAGQHILEDTRTQQTRRWWTLAGQEITVTFNQFTKYSYKYKDQPQQTFNIYKANN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRQHIIAGQHILEDTRTQQTRRWWTLAGQEITVTFNQFTKYSYKYKDQPQQTFNIYKANN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 IAANGVFHVVTGLRWQAPSGTPGDPKRTIGQILASTEAFSRFETILENCGLPSILDGPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAANGVFHVVTGLRWQAPSGTPGDPKRTIGQILASTEAFSRFETILENCGLPSILDGPGP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 FTVFAPSNEAVDSLRDGRLIYLFTAGLSKLQELVRYHIYNHGQLTVEKLISKGRILTMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTVFAPSNEAVDSLRDGRLIYLFTAGLSKLQELVRYHIYNHGQLTVEKLISKGRILTMAN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 QVLAVNISEEGRILLGPEGVPLQRVDVMAANGVIHMLDGILLPPTILPILPKHCSEEQHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVLAVNISEEGRILLGPEGVPLQRVDVMAANGVIHMLDGILLPPTILPILPKHCSEEQHK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 IVAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGC
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 CKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQC
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 QEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 EGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 VCVAIDECELDVRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHG
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LATCRAVGGGQRVCTCPPGFGGDGFSCYGDIFRELEANAHFSIFYQWLKSAGITLPADRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LATCRAVGGGQRVCTCPPGFGGDGFSCYGDIFRELEANAHFSIFYQWLKSAGITLPADRR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 VTALVPSEAAVRQLSPEDRAFWLQPRTLPNLVRAHFLQGALFEEELARLGGQEVATLNPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTALVPSEAAVRQLSPEDRAFWLQPRTLPNLVRAHFLQGALFEEELARLGGQEVATLNPT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 TRWEIRNISGRVWVQNASVDVADLLATNGVLHILSQVLLPPRGDVPGGQGLLQQLDLVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRWEIRNISGRVWVQNASVDVADLLATNGVLHILSQVLLPPRGDVPGGQGLLQQLDLVPA
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 FSLFRELLQHHGLVPQIEAATAYTIFVPTNRSLEAQGNSSHLDADTVRHHVVLGEALSME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSLFRELLQHHGLVPQIEAATAYTIFVPTNRSLEAQGNSSHLDADTVRHHVVLGEALSME
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 TLRKGGHRNSLLGPAHWIVFYNHSGQPEVNHVPLEGPMLEAPGRSLIGLSGVLTVGSSRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLRKGGHRNSLLGPAHWIVFYNHSGQPEVNHVPLEGPMLEAPGRSLIGLSGVLTVGSSRC
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 LHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDC
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 CPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCT
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 GVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTC
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 ACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINS
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 CLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKST
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600
pF1KA0 GDGQRTCTCDTAHTVGDGLTCRARVGLELLRDKHASFFSLRLLE----------------
::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDGQRTCTCDTAHTVGDGLTCRARVGLELLRDKHASFFSLRLLEIHGRLRLLPFHSCCCC
1570 1580 1590 1600 1610 1620
1610 1620 1630 1640 1650 1660
pF1KA0 ----YKELKGDGPFTIFVPHADLMSNLSQDELARIRAHRQLVFRYHVVGCRRLRSEDLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPQEYKELKGDGPFTIFVPHADLMSNLSQDELARIRAHRQLVFRYHVVGCRRLRSEDLLE
1630 1640 1650 1660 1670 1680
1670 1680 1690 1700 1710 1720
pF1KA0 QGYATALSGHPLRFSEREGSIYLNDFARVVSSDHEAVNGILHFIDRVLLPPEALHWEPDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGYATALSGHPLRFSEREGSIYLNDFARVVSSDHEAVNGILHFIDRVLLPPEALHWEPDD
1690 1700 1710 1720 1730 1740
1730 1740 1750 1760 1770 1780
pF1KA0 APIPRRNVTAAAQGFGYKIFSGLLKVAGLLPLLREASHRPFTMLWPTDAAFRALPPDRQA
:::::::::::::::::::::::::: :::
XP_016 APIPRRNVTAAAQGFGYKIFSGLLKV--LLPCGPVIVDTHARQCAQLRCVHTHACLGWSQ
1750 1760 1770 1780 1790
1790 1800 1810 1820 1830 1840
pF1KA0 WLYHEDHRDKLAAILRGHMIRNVEALASDLPNLGPLRTMHGTPISFSCSRTRPGELMVGE
XP_016 MSVGECGAPSCSVAQPPAFAN
1800 1810
>>XP_016861492 (OMIM: 608560) PREDICTED: stabilin-1 isof (2555 aa)
initn: 12469 init1: 11775 opt: 11775 Z-score: 7901.3 bits: 1476.2 E(85289): 0
Smith-Waterman score: 18330; 97.8% identity (97.8% similar) in 2590 aa overlap (1-2570:1-2555)
10 20 30 40 50 60
pF1KA0 MAGPRGLLPLCLLAFCLAGFSFVRGQVLFKGCDVKTTFVTHVPCTSCAAIKKQTCPSGWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGPRGLLPLCLLAFCLAGFSFVRGQVLFKGCDVKTTFVTHVPCTSCAAIKKQTCPSGWL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 RELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCHECPGGAETPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCHECPGGAETPC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 NGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 CLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 CSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 TCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVGDGRACYGHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVGDGRACYGHLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 HEVQKATQTGRVFLQLRVAVAMMDQGCREILTTAGPFTVLVPSVSSFSSRTMNASLAQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEVQKATQTGRVFLQLRVAVAMMDQGCREILTTAGPFTVLVPSVSSFSSRTMNASLAQQL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 CRQHIIAGQHILEDTRTQQTRRWWTLAGQEITVTFNQFTKYSYKYKDQPQQTFNIYKANN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRQHIIAGQHILEDTRTQQTRRWWTLAGQEITVTFNQFTKYSYKYKDQPQQTFNIYKANN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 IAANGVFHVVTGLRWQAPSGTPGDPKRTIGQILASTEAFSRFETILENCGLPSILDGPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAANGVFHVVTGLRWQAPSGTPGDPKRTIGQILASTEAFSRFETILENCGLPSILDGPGP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 FTVFAPSNEAVDSLRDGRLIYLFTAGLSKLQELVRYHIYNHGQLTVEKLISKGRILTMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTVFAPSNEAVDSLRDGRLIYLFTAGLSKLQELVRYHIYNHGQLTVEKLISKGRILTMAN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 QVLAVNISEEGRILLGPEGVPLQRVDVMAANGVIHMLDGILLPPTILPILPKHCSEEQHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVLAVNISEEGRILLGPEGVPLQRVDVMAANGVIHMLDGILLPPTILPILPKHCSEEQHK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 IVAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGC
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 CKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQC
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 QEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 EGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 VCVAIDECELDVRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHG
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LATCRAVGGGQRVCTCPPGFGGDGFSCYGDIFRELEANAHFSIFYQWLKSAGITLPADRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LATCRAVGGGQRVCTCPPGFGGDGFSCYGDIFRELEANAHFSIFYQWLKSAGITLPADRR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 VTALVPSEAAVRQLSPEDRAFWLQPRTLPNLVRAHFLQGALFEEELARLGGQEVATLNPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTALVPSEAAVRQLSPEDRAFWLQPRTLPNLVRAHFLQGALFEEELARLGGQEVATLNPT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 TRWEIRNISGRVWVQNASVDVADLLATNGVLHILSQVLLPPRGDVPGGQGLLQQLDLVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRWEIRNISGRVWVQNASVDVADLLATNGVLHILSQVLLPPRGDVPGGQGLLQQLDLVPA
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 FSLFRELLQHHGLVPQIEAATAYTIFVPTNRSLEAQGNSSHLDADTVRHHVVLGEALSME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSLFRELLQHHGLVPQIEAATAYTIFVPTNRSLEAQGNSSHLDADTVRHHVVLGEALSME
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 TLRKGGHRNSLLGPAHWIVFYNHSGQPEVNHVPLEGPMLEAPGRSLIGLSGVLTVGSSRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLRKGGHRNSLLGPAHWIVFYNHSGQPEVNHVPLEGPMLEAPGRSLIGLSGVLTVGSSRC
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 LHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDC
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 CPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCT
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 GVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTC
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 ACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINS
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 CLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKST
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600
pF1KA0 GDGQRTCTCDTAHTVGDGLTCRARVGLELLRDKHASFFSLRLLE----------------
::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDGQRTCTCDTAHTVGDGLTCRARVGLELLRDKHASFFSLRLLEIHGRLRLLPFHSCCCC
1570 1580 1590 1600 1610 1620
1610 1620 1630 1640 1650 1660
pF1KA0 ----YKELKGDGPFTIFVPHADLMSNLSQDELARIRAHRQLVFRYHVVGCRRLRSEDLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPQEYKELKGDGPFTIFVPHADLMSNLSQDELARIRAHRQLVFRYHVVGCRRLRSEDLLE
1630 1640 1650 1660 1670 1680
1670 1680 1690 1700 1710 1720
pF1KA0 QGYATALSGHPLRFSEREGSIYLNDFARVVSSDHEAVNGILHFIDRVLLPPEALHWEPDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGYATALSGHPLRFSEREGSIYLNDFARVVSSDHEAVNGILHFIDRVLLPPEALHWEPDD
1690 1700 1710 1720 1730 1740
1730 1740 1750 1760 1770 1780
pF1KA0 APIPRRNVTAAAQGFGYKIFSGLLKVAGLLPLLREASHRPFTMLWPTDAAFRALPPDRQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APIPRRNVTAAAQGFGYKIFSGLLKVAGLLPLLREASHRPFTMLWPTDAAFRALPPDRQA
1750 1760 1770 1780 1790 1800
1790 1800 1810 1820 1830 1840
pF1KA0 WLYHEDHRDKLAAILRGHMIRNVEALASDLPNLGPLRTMHGTPISFSCSRTRPGELMVGE
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_016 WLYHEDHRDKLAAILRGHMIRNVEALASDLPNLGPLRTMHGTPISFSCSRTRAGELMVGE
1810 1820 1830 1840 1850 1860
1850 1860 1870 1880 1890 1900
pF1KA0 DDARIVQRHLPFEGGLAYGIDQLLEPPGLGARCDHFETRPLRLNTCSICGLEPPCPEGSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDARIVQRHLPFEGGLAYGIDQLLEPPGLGARCDHFETRPLRLNTCSICGLEPPCPEGSQ
1870 1880 1890 1900 1910 1920
1910 1920 1930 1940 1950 1960
pF1KA0 EQGSPEACWRFYPKFWTSPPLHSLGLRSVWVHPSLWGRPQGLGRGCHRNCVTTTWKPSCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQGSPEACWRFYPKFWTSPPLHSLGLRSVWVHPSLWGRPQGLGRGCHRNCVTTTWKPSCC
1930 1940 1950 1960 1970 1980
1970 1980 1990 2000 2010 2020
pF1KA0 PGHYGSECQACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGHYGSECQACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQA
1990 2000 2010 2020 2030 2040
2030 2040 2050 2060 2070 2080
pF1KA0 CRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSL
2050 2060 2070 2080 2090 2100
2090 2100 2110 2120 2130 2140
pF1KA0 GYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGH
2110 2120 2130 2140 2150 2160
2150 2160 2170 2180 2190 2200
pF1KA0 RGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTDL
2170 2180 2190 2200 2210 2220
2210 2220 2230 2240 2250 2260
pF1KA0 HFQEKRAGVFHLQATSGPYGLNFSEAEAACEAQGAVLASFPQLSAAQQLGFHLCLMGWLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HFQEKRAGVFHLQATSGPYGLNFSEAEAACEAQGAVLASFPQLSAAQQLGFHLCLMGWLA
2230 2240 2250 2260 2270 2280
2270 2280 2290 2300 2310 2320
pF1KA0 NGSTAHPVVFPVADCGNGRVGIVSLGARKNLSERWDAYCFRVQDVACRCRNGFVGDGIST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGSTAHPVVFPVADCGNGRVGIVSLGARKNLSERWDAYCFRVQDVACRCRNGFVGDGIST
2290 2300 2310 2320 2330 2340
2330 2340 2350 2360 2370 2380
pF1KA0 CNGKLLDVLAATANFSTFYGMLLGYANATQRGLDFLDFLDDELTYKTLFVPVNEGFVDNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CNGKLLDVLAATANFSTFYGMLLGYANATQRGLDFLDFLDDELTYKTLFVPVNEGFVDNM
2350 2360 2370 2380 2390 2400
2390 2400 2410 2420 2430 2440
pF1KA0 TLSGPDLELHASNATLLSANASQGKLLPAHSGLSLIISDAGPDNSSWAPVAPGTVVVSRI
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLSGPDLELHASNATLLSANASQGKLLPAHSGLSLIISDAGPDNSSWAPV----------
2410 2420 2430 2440 2450
2450 2460 2470 2480 2490 2500
pF1KA0 IVWDIMAFNGIIHALASPLLAPPQPQAVLAPEAPPVAAGVGAVLAAGALLGLVAGALYLR
:::::::::::::::::::::::::::::::::::
XP_016 -------------------------QAVLAPEAPPVAAGVGAVLAAGALLGLVAGALYLR
2460 2470 2480
2510 2520 2530 2540 2550 2560
pF1KA0 ARGKPMGFGFSAFQAEDDADDDFSPWQEGTNPTLVSVPNPVFGSDTFCEPFDDSLLEEDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARGKPMGFGFSAFQAEDDADDDFSPWQEGTNPTLVSVPNPVFGSDTFCEPFDDSLLEEDF
2490 2500 2510 2520 2530 2540
2570
pF1KA0 PDTQRILTVK
::::::::::
XP_016 PDTQRILTVK
2550
>>XP_016861489 (OMIM: 608560) PREDICTED: stabilin-1 isof (2589 aa)
initn: 12471 init1: 11775 opt: 11775 Z-score: 7901.2 bits: 1476.2 E(85289): 0
Smith-Waterman score: 18626; 99.1% identity (99.2% similar) in 2590 aa overlap (1-2570:1-2589)
10 20 30 40 50 60
pF1KA0 MAGPRGLLPLCLLAFCLAGFSFVRGQVLFKGCDVKTTFVTHVPCTSCAAIKKQTCPSGWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGPRGLLPLCLLAFCLAGFSFVRGQVLFKGCDVKTTFVTHVPCTSCAAIKKQTCPSGWL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 RELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCHECPGGAETPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCHECPGGAETPC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 NGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 CLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 CSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 TCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVGDGRACYGHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVGDGRACYGHLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 HEVQKATQTGRVFLQLRVAVAMMDQGCREILTTAGPFTVLVPSVSSFSSRTMNASLAQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEVQKATQTGRVFLQLRVAVAMMDQGCREILTTAGPFTVLVPSVSSFSSRTMNASLAQQL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 CRQHIIAGQHILEDTRTQQTRRWWTLAGQEITVTFNQFTKYSYKYKDQPQQTFNIYKANN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRQHIIAGQHILEDTRTQQTRRWWTLAGQEITVTFNQFTKYSYKYKDQPQQTFNIYKANN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 IAANGVFHVVTGLRWQAPSGTPGDPKRTIGQILASTEAFSRFETILENCGLPSILDGPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAANGVFHVVTGLRWQAPSGTPGDPKRTIGQILASTEAFSRFETILENCGLPSILDGPGP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 FTVFAPSNEAVDSLRDGRLIYLFTAGLSKLQELVRYHIYNHGQLTVEKLISKGRILTMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTVFAPSNEAVDSLRDGRLIYLFTAGLSKLQELVRYHIYNHGQLTVEKLISKGRILTMAN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 QVLAVNISEEGRILLGPEGVPLQRVDVMAANGVIHMLDGILLPPTILPILPKHCSEEQHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVLAVNISEEGRILLGPEGVPLQRVDVMAANGVIHMLDGILLPPTILPILPKHCSEEQHK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 IVAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGC
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 CKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQC
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 QEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 EGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 VCVAIDECELDVRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHG
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LATCRAVGGGQRVCTCPPGFGGDGFSCYGDIFRELEANAHFSIFYQWLKSAGITLPADRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LATCRAVGGGQRVCTCPPGFGGDGFSCYGDIFRELEANAHFSIFYQWLKSAGITLPADRR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 VTALVPSEAAVRQLSPEDRAFWLQPRTLPNLVRAHFLQGALFEEELARLGGQEVATLNPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTALVPSEAAVRQLSPEDRAFWLQPRTLPNLVRAHFLQGALFEEELARLGGQEVATLNPT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 TRWEIRNISGRVWVQNASVDVADLLATNGVLHILSQVLLPPRGDVPGGQGLLQQLDLVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRWEIRNISGRVWVQNASVDVADLLATNGVLHILSQVLLPPRGDVPGGQGLLQQLDLVPA
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 FSLFRELLQHHGLVPQIEAATAYTIFVPTNRSLEAQGNSSHLDADTVRHHVVLGEALSME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSLFRELLQHHGLVPQIEAATAYTIFVPTNRSLEAQGNSSHLDADTVRHHVVLGEALSME
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 TLRKGGHRNSLLGPAHWIVFYNHSGQPEVNHVPLEGPMLEAPGRSLIGLSGVLTVGSSRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLRKGGHRNSLLGPAHWIVFYNHSGQPEVNHVPLEGPMLEAPGRSLIGLSGVLTVGSSRC
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 LHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDC
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 CPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCT
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 GVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTC
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 ACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINS
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 CLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKST
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600
pF1KA0 GDGQRTCTCDTAHTVGDGLTCRARVGLELLRDKHASFFSLRLLE----------------
::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDGQRTCTCDTAHTVGDGLTCRARVGLELLRDKHASFFSLRLLEIHGRLRLLPFHSCCCC
1570 1580 1590 1600 1610 1620
1610 1620 1630 1640 1650 1660
pF1KA0 ----YKELKGDGPFTIFVPHADLMSNLSQDELARIRAHRQLVFRYHVVGCRRLRSEDLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPQEYKELKGDGPFTIFVPHADLMSNLSQDELARIRAHRQLVFRYHVVGCRRLRSEDLLE
1630 1640 1650 1660 1670 1680
1670 1680 1690 1700 1710 1720
pF1KA0 QGYATALSGHPLRFSEREGSIYLNDFARVVSSDHEAVNGILHFIDRVLLPPEALHWEPDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGYATALSGHPLRFSEREGSIYLNDFARVVSSDHEAVNGILHFIDRVLLPPEALHWEPDD
1690 1700 1710 1720 1730 1740
1730 1740 1750 1760 1770 1780
pF1KA0 APIPRRNVTAAAQGFGYKIFSGLLKVAGLLPLLREASHRPFTMLWPTDAAFRALPPDRQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APIPRRNVTAAAQGFGYKIFSGLLKVAGLLPLLREASHRPFTMLWPTDAAFRALPPDRQA
1750 1760 1770 1780 1790 1800
1790 1800 1810 1820 1830 1840
pF1KA0 WLYHEDHRDKLAAILRGHMIRNVEALASDLPNLGPLRTMHGTPISFSCSRTRPGELMVGE
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_016 WLYHEDHRDKLAAILRGHMIRNVEALASDLPNLGPLRTMHGTPISFSCSRTRAGELMVGE
1810 1820 1830 1840 1850 1860
1850 1860 1870 1880 1890 1900
pF1KA0 DDARIVQRHLPFEGGLAYGIDQLLEPPGLGARCDHFETRPLRLNTCSICGLEPPCPEGSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDARIVQRHLPFEGGLAYGIDQLLEPPGLGARCDHFETRPLRLNTCSICGLEPPCPEGSQ
1870 1880 1890 1900 1910 1920
1910 1920 1930 1940 1950 1960
pF1KA0 EQGSPEACWRFYPKFWTSPPLHSLGLRSVWVHPSLWGRPQGLGRGCHRNCVTTTWKPSCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQGSPEACWRFYPKFWTSPPLHSLGLRSVWVHPSLWGRPQGLGRGCHRNCVTTTWKPSCC
1930 1940 1950 1960 1970 1980
1970 1980 1990 2000 2010 2020
pF1KA0 PGHYGSECQACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGHYGSECQACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQA
1990 2000 2010 2020 2030 2040
2030 2040 2050 2060 2070 2080
pF1KA0 CRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSL
2050 2060 2070 2080 2090 2100
2090 2100 2110 2120 2130 2140
pF1KA0 GYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGH
2110 2120 2130 2140 2150 2160
2150 2160 2170 2180 2190 2200
pF1KA0 RGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTDL
2170 2180 2190 2200 2210 2220
2210 2220 2230 2240 2250 2260
pF1KA0 HFQEKRAGVFHLQATSGPYGLNFSEAEAACEAQGAVLASFPQLSAAQQLGFHLCLMGWLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HFQEKRAGVFHLQATSGPYGLNFSEAEAACEAQGAVLASFPQLSAAQQLGFHLCLMGWLA
2230 2240 2250 2260 2270 2280
2270 2280 2290 2300 2310 2320
pF1KA0 NGSTAHPVVFPVADCGNGRVGIVSLGARKNLSERWDAYCFRVQDVACRCRNGFVGDGIST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGSTAHPVVFPVADCGNGRVGIVSLGARKNLSERWDAYCFRVQDVACRCRNGFVGDGIST
2290 2300 2310 2320 2330 2340
2330 2340 2350 2360 2370 2380
pF1KA0 CNGKLLDVLAATANFSTFYGMLLGYANATQRGLDFLDFLDDELTYKTLFVPVNEGFVDNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CNGKLLDVLAATANFSTFYGMLLGYANATQRGLDFLDFLDDELTYKTLFVPVNEGFVDNM
2350 2360 2370 2380 2390 2400
2390 2400 2410 2420 2430 2440
pF1KA0 TLSGPDLELHASNATLLSANASQGKLLPAHSGLSLIISDAGPDNSSWAPVAPGTVVVSRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLSGPDLELHASNATLLSANASQGKLLPAHSGLSLIISDAGPDNSSWAPVAPGTVVVSRI
2410 2420 2430 2440 2450 2460
2450 2460 2470 2480 2490 2500
pF1KA0 IVWDIMAFNGIIHALASPLLAPPQPQAVLAPEAPPVAAGVGAVLAAGALLGLVAGALYLR
::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
XP_016 IVWDIMAFNGIIHALASPLLAPPQP-AVLAPEAPPVAAGVGAVLAAGALLGLVAGALYLR
2470 2480 2490 2500 2510
2510 2520 2530 2540 2550 2560
pF1KA0 ARGKPMGFGFSAFQAEDDADDDFSPWQEGTNPTLVSVPNPVFGSDTFCEPFDDSLLEEDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARGKPMGFGFSAFQAEDDADDDFSPWQEGTNPTLVSVPNPVFGSDTFCEPFDDSLLEEDF
2520 2530 2540 2550 2560 2570
2570
pF1KA0 PDTQRILTVK
::::::::::
XP_016 PDTQRILTVK
2580
>>XP_016861488 (OMIM: 608560) PREDICTED: stabilin-1 isof (2590 aa)
initn: 11775 init1: 11775 opt: 11775 Z-score: 7901.2 bits: 1476.2 E(85289): 0
Smith-Waterman score: 18645; 99.2% identity (99.2% similar) in 2590 aa overlap (1-2570:1-2590)
10 20 30 40 50 60
pF1KA0 MAGPRGLLPLCLLAFCLAGFSFVRGQVLFKGCDVKTTFVTHVPCTSCAAIKKQTCPSGWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGPRGLLPLCLLAFCLAGFSFVRGQVLFKGCDVKTTFVTHVPCTSCAAIKKQTCPSGWL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 RELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCHECPGGAETPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCHECPGGAETPC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 NGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 CLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 CSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 TCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVGDGRACYGHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVGDGRACYGHLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 HEVQKATQTGRVFLQLRVAVAMMDQGCREILTTAGPFTVLVPSVSSFSSRTMNASLAQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEVQKATQTGRVFLQLRVAVAMMDQGCREILTTAGPFTVLVPSVSSFSSRTMNASLAQQL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 CRQHIIAGQHILEDTRTQQTRRWWTLAGQEITVTFNQFTKYSYKYKDQPQQTFNIYKANN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRQHIIAGQHILEDTRTQQTRRWWTLAGQEITVTFNQFTKYSYKYKDQPQQTFNIYKANN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 IAANGVFHVVTGLRWQAPSGTPGDPKRTIGQILASTEAFSRFETILENCGLPSILDGPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAANGVFHVVTGLRWQAPSGTPGDPKRTIGQILASTEAFSRFETILENCGLPSILDGPGP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 FTVFAPSNEAVDSLRDGRLIYLFTAGLSKLQELVRYHIYNHGQLTVEKLISKGRILTMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTVFAPSNEAVDSLRDGRLIYLFTAGLSKLQELVRYHIYNHGQLTVEKLISKGRILTMAN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 QVLAVNISEEGRILLGPEGVPLQRVDVMAANGVIHMLDGILLPPTILPILPKHCSEEQHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVLAVNISEEGRILLGPEGVPLQRVDVMAANGVIHMLDGILLPPTILPILPKHCSEEQHK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 IVAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGC
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 CKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQC
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 QEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 EGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 VCVAIDECELDVRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHG
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LATCRAVGGGQRVCTCPPGFGGDGFSCYGDIFRELEANAHFSIFYQWLKSAGITLPADRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LATCRAVGGGQRVCTCPPGFGGDGFSCYGDIFRELEANAHFSIFYQWLKSAGITLPADRR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 VTALVPSEAAVRQLSPEDRAFWLQPRTLPNLVRAHFLQGALFEEELARLGGQEVATLNPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTALVPSEAAVRQLSPEDRAFWLQPRTLPNLVRAHFLQGALFEEELARLGGQEVATLNPT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 TRWEIRNISGRVWVQNASVDVADLLATNGVLHILSQVLLPPRGDVPGGQGLLQQLDLVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRWEIRNISGRVWVQNASVDVADLLATNGVLHILSQVLLPPRGDVPGGQGLLQQLDLVPA
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 FSLFRELLQHHGLVPQIEAATAYTIFVPTNRSLEAQGNSSHLDADTVRHHVVLGEALSME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSLFRELLQHHGLVPQIEAATAYTIFVPTNRSLEAQGNSSHLDADTVRHHVVLGEALSME
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 TLRKGGHRNSLLGPAHWIVFYNHSGQPEVNHVPLEGPMLEAPGRSLIGLSGVLTVGSSRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLRKGGHRNSLLGPAHWIVFYNHSGQPEVNHVPLEGPMLEAPGRSLIGLSGVLTVGSSRC
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 LHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDC
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 CPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCT
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 GVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTC
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 ACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINS
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 CLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKST
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600
pF1KA0 GDGQRTCTCDTAHTVGDGLTCRARVGLELLRDKHASFFSLRLLE----------------
::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDGQRTCTCDTAHTVGDGLTCRARVGLELLRDKHASFFSLRLLEIHGRLRLLPFHSCCCC
1570 1580 1590 1600 1610 1620
1610 1620 1630 1640 1650 1660
pF1KA0 ----YKELKGDGPFTIFVPHADLMSNLSQDELARIRAHRQLVFRYHVVGCRRLRSEDLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPQEYKELKGDGPFTIFVPHADLMSNLSQDELARIRAHRQLVFRYHVVGCRRLRSEDLLE
1630 1640 1650 1660 1670 1680
1670 1680 1690 1700 1710 1720
pF1KA0 QGYATALSGHPLRFSEREGSIYLNDFARVVSSDHEAVNGILHFIDRVLLPPEALHWEPDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGYATALSGHPLRFSEREGSIYLNDFARVVSSDHEAVNGILHFIDRVLLPPEALHWEPDD
1690 1700 1710 1720 1730 1740
1730 1740 1750 1760 1770 1780
pF1KA0 APIPRRNVTAAAQGFGYKIFSGLLKVAGLLPLLREASHRPFTMLWPTDAAFRALPPDRQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APIPRRNVTAAAQGFGYKIFSGLLKVAGLLPLLREASHRPFTMLWPTDAAFRALPPDRQA
1750 1760 1770 1780 1790 1800
1790 1800 1810 1820 1830 1840
pF1KA0 WLYHEDHRDKLAAILRGHMIRNVEALASDLPNLGPLRTMHGTPISFSCSRTRPGELMVGE
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_016 WLYHEDHRDKLAAILRGHMIRNVEALASDLPNLGPLRTMHGTPISFSCSRTRAGELMVGE
1810 1820 1830 1840 1850 1860
1850 1860 1870 1880 1890 1900
pF1KA0 DDARIVQRHLPFEGGLAYGIDQLLEPPGLGARCDHFETRPLRLNTCSICGLEPPCPEGSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDARIVQRHLPFEGGLAYGIDQLLEPPGLGARCDHFETRPLRLNTCSICGLEPPCPEGSQ
1870 1880 1890 1900 1910 1920
1910 1920 1930 1940 1950 1960
pF1KA0 EQGSPEACWRFYPKFWTSPPLHSLGLRSVWVHPSLWGRPQGLGRGCHRNCVTTTWKPSCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQGSPEACWRFYPKFWTSPPLHSLGLRSVWVHPSLWGRPQGLGRGCHRNCVTTTWKPSCC
1930 1940 1950 1960 1970 1980
1970 1980 1990 2000 2010 2020
pF1KA0 PGHYGSECQACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGHYGSECQACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQA
1990 2000 2010 2020 2030 2040
2030 2040 2050 2060 2070 2080
pF1KA0 CRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSL
2050 2060 2070 2080 2090 2100
2090 2100 2110 2120 2130 2140
pF1KA0 GYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGH
2110 2120 2130 2140 2150 2160
2150 2160 2170 2180 2190 2200
pF1KA0 RGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTDL
2170 2180 2190 2200 2210 2220
2210 2220 2230 2240 2250 2260
pF1KA0 HFQEKRAGVFHLQATSGPYGLNFSEAEAACEAQGAVLASFPQLSAAQQLGFHLCLMGWLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HFQEKRAGVFHLQATSGPYGLNFSEAEAACEAQGAVLASFPQLSAAQQLGFHLCLMGWLA
2230 2240 2250 2260 2270 2280
2270 2280 2290 2300 2310 2320
pF1KA0 NGSTAHPVVFPVADCGNGRVGIVSLGARKNLSERWDAYCFRVQDVACRCRNGFVGDGIST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGSTAHPVVFPVADCGNGRVGIVSLGARKNLSERWDAYCFRVQDVACRCRNGFVGDGIST
2290 2300 2310 2320 2330 2340
2330 2340 2350 2360 2370 2380
pF1KA0 CNGKLLDVLAATANFSTFYGMLLGYANATQRGLDFLDFLDDELTYKTLFVPVNEGFVDNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CNGKLLDVLAATANFSTFYGMLLGYANATQRGLDFLDFLDDELTYKTLFVPVNEGFVDNM
2350 2360 2370 2380 2390 2400
2390 2400 2410 2420 2430 2440
pF1KA0 TLSGPDLELHASNATLLSANASQGKLLPAHSGLSLIISDAGPDNSSWAPVAPGTVVVSRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLSGPDLELHASNATLLSANASQGKLLPAHSGLSLIISDAGPDNSSWAPVAPGTVVVSRI
2410 2420 2430 2440 2450 2460
2450 2460 2470 2480 2490 2500
pF1KA0 IVWDIMAFNGIIHALASPLLAPPQPQAVLAPEAPPVAAGVGAVLAAGALLGLVAGALYLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVWDIMAFNGIIHALASPLLAPPQPQAVLAPEAPPVAAGVGAVLAAGALLGLVAGALYLR
2470 2480 2490 2500 2510 2520
2510 2520 2530 2540 2550 2560
pF1KA0 ARGKPMGFGFSAFQAEDDADDDFSPWQEGTNPTLVSVPNPVFGSDTFCEPFDDSLLEEDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARGKPMGFGFSAFQAEDDADDDFSPWQEGTNPTLVSVPNPVFGSDTFCEPFDDSLLEEDF
2530 2540 2550 2560 2570 2580
2570
pF1KA0 PDTQRILTVK
::::::::::
XP_016 PDTQRILTVK
2590
>>XP_016861487 (OMIM: 608560) PREDICTED: stabilin-1 isof (2615 aa)
initn: 12704 init1: 11775 opt: 11775 Z-score: 7901.2 bits: 1476.2 E(85289): 0
Smith-Waterman score: 18500; 98.2% identity (98.2% similar) in 2602 aa overlap (1-2557:1-2602)
10 20 30 40 50 60
pF1KA0 MAGPRGLLPLCLLAFCLAGFSFVRGQVLFKGCDVKTTFVTHVPCTSCAAIKKQTCPSGWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGPRGLLPLCLLAFCLAGFSFVRGQVLFKGCDVKTTFVTHVPCTSCAAIKKQTCPSGWL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 RELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCHECPGGAETPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCHECPGGAETPC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 NGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 CLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 CSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 TCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVGDGRACYGHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVGDGRACYGHLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 HEVQKATQTGRVFLQLRVAVAMMDQGCREILTTAGPFTVLVPSVSSFSSRTMNASLAQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEVQKATQTGRVFLQLRVAVAMMDQGCREILTTAGPFTVLVPSVSSFSSRTMNASLAQQL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 CRQHIIAGQHILEDTRTQQTRRWWTLAGQEITVTFNQFTKYSYKYKDQPQQTFNIYKANN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRQHIIAGQHILEDTRTQQTRRWWTLAGQEITVTFNQFTKYSYKYKDQPQQTFNIYKANN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 IAANGVFHVVTGLRWQAPSGTPGDPKRTIGQILASTEAFSRFETILENCGLPSILDGPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAANGVFHVVTGLRWQAPSGTPGDPKRTIGQILASTEAFSRFETILENCGLPSILDGPGP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 FTVFAPSNEAVDSLRDGRLIYLFTAGLSKLQELVRYHIYNHGQLTVEKLISKGRILTMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTVFAPSNEAVDSLRDGRLIYLFTAGLSKLQELVRYHIYNHGQLTVEKLISKGRILTMAN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 QVLAVNISEEGRILLGPEGVPLQRVDVMAANGVIHMLDGILLPPTILPILPKHCSEEQHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVLAVNISEEGRILLGPEGVPLQRVDVMAANGVIHMLDGILLPPTILPILPKHCSEEQHK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 IVAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGC
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 CKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQC
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 QEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 EGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 VCVAIDECELDVRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHG
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LATCRAVGGGQRVCTCPPGFGGDGFSCYGDIFRELEANAHFSIFYQWLKSAGITLPADRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LATCRAVGGGQRVCTCPPGFGGDGFSCYGDIFRELEANAHFSIFYQWLKSAGITLPADRR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 VTALVPSEAAVRQLSPEDRAFWLQPRTLPNLVRAHFLQGALFEEELARLGGQEVATLNPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTALVPSEAAVRQLSPEDRAFWLQPRTLPNLVRAHFLQGALFEEELARLGGQEVATLNPT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 TRWEIRNISGRVWVQNASVDVADLLATNGVLHILSQVLLPPRGDVPGGQGLLQQLDLVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRWEIRNISGRVWVQNASVDVADLLATNGVLHILSQVLLPPRGDVPGGQGLLQQLDLVPA
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 FSLFRELLQHHGLVPQIEAATAYTIFVPTNRSLEAQGNSSHLDADTVRHHVVLGEALSME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSLFRELLQHHGLVPQIEAATAYTIFVPTNRSLEAQGNSSHLDADTVRHHVVLGEALSME
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 TLRKGGHRNSLLGPAHWIVFYNHSGQPEVNHVPLEGPMLEAPGRSLIGLSGVLTVGSSRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLRKGGHRNSLLGPAHWIVFYNHSGQPEVNHVPLEGPMLEAPGRSLIGLSGVLTVGSSRC
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 LHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDC
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 CPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCT
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 GVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTC
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 ACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINS
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 CLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKST
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600
pF1KA0 GDGQRTCTCDTAHTVGDGLTCRARVGLELLRDKHASFFSLRLLE----------------
::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDGQRTCTCDTAHTVGDGLTCRARVGLELLRDKHASFFSLRLLEIHGRLRLLPFHSCCCC
1570 1580 1590 1600 1610 1620
1610 1620 1630 1640 1650 1660
pF1KA0 ----YKELKGDGPFTIFVPHADLMSNLSQDELARIRAHRQLVFRYHVVGCRRLRSEDLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPQEYKELKGDGPFTIFVPHADLMSNLSQDELARIRAHRQLVFRYHVVGCRRLRSEDLLE
1630 1640 1650 1660 1670 1680
1670 1680 1690 1700 1710 1720
pF1KA0 QGYATALSGHPLRFSEREGSIYLNDFARVVSSDHEAVNGILHFIDRVLLPPEALHWEPDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGYATALSGHPLRFSEREGSIYLNDFARVVSSDHEAVNGILHFIDRVLLPPEALHWEPDD
1690 1700 1710 1720 1730 1740
1730 1740 1750 1760 1770 1780
pF1KA0 APIPRRNVTAAAQGFGYKIFSGLLKVAGLLPLLREASHRPFTMLWPTDAAFRALPPDRQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APIPRRNVTAAAQGFGYKIFSGLLKVAGLLPLLREASHRPFTMLWPTDAAFRALPPDRQA
1750 1760 1770 1780 1790 1800
1790 1800 1810 1820 1830 1840
pF1KA0 WLYHEDHRDKLAAILRGHMIRNVEALASDLPNLGPLRTMHGTPISFSCSRTRPGELMVGE
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_016 WLYHEDHRDKLAAILRGHMIRNVEALASDLPNLGPLRTMHGTPISFSCSRTRAGELMVGE
1810 1820 1830 1840 1850 1860
1850 1860 1870 1880 1890 1900
pF1KA0 DDARIVQRHLPFEGGLAYGIDQLLEPPGLGARCDHFETRPLRLNTCSICGLEPPCPEGSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDARIVQRHLPFEGGLAYGIDQLLEPPGLGARCDHFETRPLRLNTCSICGLEPPCPEGSQ
1870 1880 1890 1900 1910 1920
1910 1920 1930 1940 1950 1960
pF1KA0 EQGSPEACWRFYPKFWTSPPLHSLGLRSVWVHPSLWGRPQGLGRGCHRNCVTTTWKPSCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQGSPEACWRFYPKFWTSPPLHSLGLRSVWVHPSLWGRPQGLGRGCHRNCVTTTWKPSCC
1930 1940 1950 1960 1970 1980
1970 1980 1990 2000 2010 2020
pF1KA0 PGHYGSECQACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGHYGSECQACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQA
1990 2000 2010 2020 2030 2040
2030 2040 2050 2060 2070 2080
pF1KA0 CRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSL
2050 2060 2070 2080 2090 2100
2090 2100 2110 2120 2130 2140
pF1KA0 GYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGH
2110 2120 2130 2140 2150 2160
2150 2160 2170 2180 2190 2200
pF1KA0 RGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTDL
2170 2180 2190 2200 2210 2220
2210 2220 2230 2240 2250 2260
pF1KA0 HFQEKRAGVFHLQATSGPYGLNFSEAEAACEAQGAVLASFPQLSAAQQLGFHLCLMGWLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HFQEKRAGVFHLQATSGPYGLNFSEAEAACEAQGAVLASFPQLSAAQQLGFHLCLMGWLA
2230 2240 2250 2260 2270 2280
2270 2280 2290 2300 2310 2320
pF1KA0 NGSTAHPVVFPVADCGNGRVGIVSLGARKNLSERWDAYCFRVQDVACRCRNGFVGDGIST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGSTAHPVVFPVADCGNGRVGIVSLGARKNLSERWDAYCFRVQDVACRCRNGFVGDGIST
2290 2300 2310 2320 2330 2340
2330 2340 2350 2360 2370 2380
pF1KA0 CNGKLLDVLAATANFSTFYGMLLGYANATQRGLDFLDFLDDELTYKTLFVPVNEGFVDNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CNGKLLDVLAATANFSTFYGMLLGYANATQRGLDFLDFLDDELTYKTLFVPVNEGFVDNM
2350 2360 2370 2380 2390 2400
2390 2400 2410 2420 2430
pF1KA0 TLSGPDLELHASNATLLSANASQGKLLPAHSGLSLIISDAGPDNSSWAPV----------
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLSGPDLELHASNATLLSANASQGKLLPAHSGLSLIISDAGPDNSSWAPVVSLATVPPCW
2410 2420 2430 2440 2450 2460
2440 2450 2460 2470
pF1KA0 ---------------APGTVVVSRIIVWDIMAFNGIIHALASPLLAPPQPQAVLAPEAPP
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 PWPSLTVGLTLVSLQAPGTVVVSRIIVWDIMAFNGIIHALASPLLAPPQPQAVLAPEAPP
2470 2480 2490 2500 2510 2520
2480 2490 2500 2510 2520 2530
pF1KA0 VAAGVGAVLAAGALLGLVAGALYLRARGKPMGFGFSAFQAEDDADDDFSPWQEGTNPTLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAAGVGAVLAAGALLGLVAGALYLRARGKPMGFGFSAFQAEDDADDDFSPWQEGTNPTLV
2530 2540 2550 2560 2570 2580
2540 2550 2560 2570
pF1KA0 SVPNPVFGSDTFCEPFDDSLLEEDFPDTQRILTVK
::::::::::::::::::::::
XP_016 SVPNPVFGSDTFCEPFDDSLLEEDFPDTQRILTVK
2590 2600 2610
>>XP_006713128 (OMIM: 608560) PREDICTED: stabilin-1 isof (1619 aa)
initn: 12552 init1: 11676 opt: 11682 Z-score: 7841.3 bits: 1464.5 E(85289): 0
Smith-Waterman score: 11682; 99.4% identity (99.6% similar) in 1600 aa overlap (1-1597:1-1600)
10 20 30 40 50 60
pF1KA0 MAGPRGLLPLCLLAFCLAGFSFVRGQVLFKGCDVKTTFVTHVPCTSCAAIKKQTCPSGWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAGPRGLLPLCLLAFCLAGFSFVRGQVLFKGCDVKTTFVTHVPCTSCAAIKKQTCPSGWL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 RELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCHECPGGAETPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCHECPGGAETPC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 NGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 CLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 CSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 TCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVGDGRACYGHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVGDGRACYGHLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 HEVQKATQTGRVFLQLRVAVAMMDQGCREILTTAGPFTVLVPSVSSFSSRTMNASLAQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HEVQKATQTGRVFLQLRVAVAMMDQGCREILTTAGPFTVLVPSVSSFSSRTMNASLAQQL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 CRQHIIAGQHILEDTRTQQTRRWWTLAGQEITVTFNQFTKYSYKYKDQPQQTFNIYKANN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CRQHIIAGQHILEDTRTQQTRRWWTLAGQEITVTFNQFTKYSYKYKDQPQQTFNIYKANN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 IAANGVFHVVTGLRWQAPSGTPGDPKRTIGQILASTEAFSRFETILENCGLPSILDGPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IAANGVFHVVTGLRWQAPSGTPGDPKRTIGQILASTEAFSRFETILENCGLPSILDGPGP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 FTVFAPSNEAVDSLRDGRLIYLFTAGLSKLQELVRYHIYNHGQLTVEKLISKGRILTMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FTVFAPSNEAVDSLRDGRLIYLFTAGLSKLQELVRYHIYNHGQLTVEKLISKGRILTMAN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 QVLAVNISEEGRILLGPEGVPLQRVDVMAANGVIHMLDGILLPPTILPILPKHCSEEQHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QVLAVNISEEGRILLGPEGVPLQRVDVMAANGVIHMLDGILLPPTILPILPKHCSEEQHK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 IVAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IVAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGC
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 CKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQC
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 QEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 EGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 VCVAIDECELDVRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHG
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 LATCRAVGGGQRVCTCPPGFGGDGFSCYGDIFRELEANAHFSIFYQWLKSAGITLPADRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LATCRAVGGGQRVCTCPPGFGGDGFSCYGDIFRELEANAHFSIFYQWLKSAGITLPADRR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 VTALVPSEAAVRQLSPEDRAFWLQPRTLPNLVRAHFLQGALFEEELARLGGQEVATLNPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VTALVPSEAAVRQLSPEDRAFWLQPRTLPNLVRAHFLQGALFEEELARLGGQEVATLNPT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 TRWEIRNISGRVWVQNASVDVADLLATNGVLHILSQVLLPPRGDVPGGQGLLQQLDLVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TRWEIRNISGRVWVQNASVDVADLLATNGVLHILSQVLLPPRGDVPGGQGLLQQLDLVPA
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 FSLFRELLQHHGLVPQIEAATAYTIFVPTNRSLEAQGNSSHLDADTVRHHVVLGEALSME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FSLFRELLQHHGLVPQIEAATAYTIFVPTNRSLEAQGNSSHLDADTVRHHVVLGEALSME
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 TLRKGGHRNSLLGPAHWIVFYNHSGQPEVNHVPLEGPMLEAPGRSLIGLSGVLTVGSSRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TLRKGGHRNSLLGPAHWIVFYNHSGQPEVNHVPLEGPMLEAPGRSLIGLSGVLTVGSSRC
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 LHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDC
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 CPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCT
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 GVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTC
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 ACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINS
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 CLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKST
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610
pF1KA0 GDGQRTCTCDTAHTVGDGLTCRARVGLELLR---DKHASFFSLRLLEYKELKGDGPFTIF
::::::::::::::::::::::::::: : : :.: ..
XP_006 GDGQRTCTCDTAHTVGDGLTCRARVGLTLGRRCWDRHQALNGGRPKSELTLAPPGAPEG
1570 1580 1590 1600 1610
1620 1630 1640 1650 1660 1670
pF1KA0 VPHADLMSNLSQDELARIRAHRQLVFRYHVVGCRRLRSEDLLEQGYATALSGHPLRFSER
2570 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 19:35:49 2016 done: Thu Nov 3 19:35:53 2016
Total Scan time: 24.640 Total Display time: 2.320
Function used was FASTA [36.3.4 Apr, 2011]