Result of FASTA (omim) for
pF1KA0231
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0231, 803 aa
1>>>pF1KA0231 803 - 803 aa - 803 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4069+/-0.000477; mu= 15.0071+/- 0.030
mean_var=106.6780+/-22.932, 0's: 0 Z-trim(111.2): 356 B-trim: 1176 in 2/49
Lambda= 0.124176
statistics sampled from 19331 (19789) to 19331 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.589), E-opt: 0.2 (0.232), width: 16
Scan time: 11.410
The best scores are: opt bits E(85289)
XP_005270759 (OMIM: 612888) PREDICTED: volume-regu ( 803) 5285 958.7 0
XP_011539448 (OMIM: 612888) PREDICTED: volume-regu ( 803) 5285 958.7 0
XP_011539447 (OMIM: 612888) PREDICTED: volume-regu ( 803) 5285 958.7 0
XP_011539446 (OMIM: 612888) PREDICTED: volume-regu ( 803) 5285 958.7 0
XP_016856373 (OMIM: 612888) PREDICTED: volume-regu ( 803) 5285 958.7 0
XP_016856372 (OMIM: 612888) PREDICTED: volume-regu ( 803) 5285 958.7 0
XP_011539445 (OMIM: 612888) PREDICTED: volume-regu ( 803) 5285 958.7 0
XP_005270758 (OMIM: 612888) PREDICTED: volume-regu ( 803) 5285 958.7 0
XP_005270760 (OMIM: 612888) PREDICTED: volume-regu ( 803) 5285 958.7 0
NP_056165 (OMIM: 612888) volume-regulated anion ch ( 803) 5285 958.7 0
NP_001127948 (OMIM: 612888) volume-regulated anion ( 803) 5285 958.7 0
XP_016856374 (OMIM: 612888) PREDICTED: volume-regu ( 803) 5285 958.7 0
XP_016856375 (OMIM: 612888) PREDICTED: volume-regu ( 731) 4676 849.5 0
XP_011539450 (OMIM: 612888) PREDICTED: volume-regu ( 731) 4676 849.5 0
XP_006717249 (OMIM: 608360,613506) PREDICTED: volu ( 810) 3188 583.0 1.8e-165
XP_011517165 (OMIM: 608360,613506) PREDICTED: volu ( 810) 3188 583.0 1.8e-165
NP_062540 (OMIM: 608360,613506) volume-regulated a ( 810) 3188 583.0 1.8e-165
XP_005252153 (OMIM: 608360,613506) PREDICTED: volu ( 810) 3188 583.0 1.8e-165
XP_005252152 (OMIM: 608360,613506) PREDICTED: volu ( 810) 3188 583.0 1.8e-165
XP_011517166 (OMIM: 608360,613506) PREDICTED: volu ( 810) 3188 583.0 1.8e-165
XP_011517167 (OMIM: 608360,613506) PREDICTED: volu ( 810) 3188 583.0 1.8e-165
NP_001120717 (OMIM: 608360,613506) volume-regulate ( 810) 3188 583.0 1.8e-165
NP_001120716 (OMIM: 608360,613506) volume-regulate ( 810) 3188 583.0 1.8e-165
NP_115646 (OMIM: 612889) volume-regulated anion ch ( 803) 2779 509.7 2e-143
XP_011540584 (OMIM: 612889) PREDICTED: volume-regu ( 803) 2778 509.5 2.2e-143
XP_016857992 (OMIM: 612889) PREDICTED: volume-regu ( 803) 2778 509.5 2.2e-143
XP_006711023 (OMIM: 612889) PREDICTED: volume-regu ( 808) 2778 509.5 2.3e-143
XP_011526621 (OMIM: 612891) PREDICTED: volume-regu ( 796) 2494 458.7 4.6e-128
NP_001255213 (OMIM: 612891) volume-regulated anion ( 796) 2494 458.7 4.6e-128
NP_079337 (OMIM: 612891) volume-regulated anion ch ( 796) 2494 458.7 4.6e-128
XP_016857089 (OMIM: 612890) PREDICTED: volume-regu ( 858) 2402 442.2 4.5e-123
XP_016857088 (OMIM: 612890) PREDICTED: volume-regu ( 858) 2402 442.2 4.5e-123
XP_016857090 (OMIM: 612890) PREDICTED: volume-regu ( 858) 2402 442.2 4.5e-123
NP_001127951 (OMIM: 612890) volume-regulated anion ( 858) 2402 442.2 4.5e-123
NP_060573 (OMIM: 612890) volume-regulated anion ch ( 858) 2402 442.2 4.5e-123
XP_016857091 (OMIM: 612890) PREDICTED: volume-regu ( 858) 2402 442.2 4.5e-123
XP_011539991 (OMIM: 612890) PREDICTED: volume-regu ( 858) 2402 442.2 4.5e-123
XP_016857993 (OMIM: 612889) PREDICTED: volume-regu ( 773) 2321 427.7 9.6e-119
XP_011540585 (OMIM: 612889) PREDICTED: volume-regu ( 778) 2321 427.7 9.7e-119
NP_001255214 (OMIM: 612891) volume-regulated anion ( 667) 2147 396.4 2.1e-109
NP_001255968 (OMIM: 602775,607721) leucine-rich re ( 536) 414 85.9 5e-16
NP_001311265 (OMIM: 602775,607721) leucine-rich re ( 582) 414 85.9 5.3e-16
NP_001311266 (OMIM: 602775,607721) leucine-rich re ( 582) 414 85.9 5.3e-16
NP_031399 (OMIM: 602775,607721) leucine-rich repea ( 582) 414 85.9 5.3e-16
XP_016872192 (OMIM: 602775,607721) PREDICTED: leuc ( 582) 414 85.9 5.3e-16
XP_016872193 (OMIM: 602775,607721) PREDICTED: leuc ( 582) 414 85.9 5.3e-16
XP_016872191 (OMIM: 602775,607721) PREDICTED: leuc ( 582) 414 85.9 5.3e-16
XP_016866486 (OMIM: 608195) PREDICTED: leucine-ric ( 331) 407 84.5 8.1e-16
NP_060684 (OMIM: 608195) leucine-rich repeat-conta ( 524) 407 84.7 1.2e-15
XP_011513028 (OMIM: 608195) PREDICTED: leucine-ric ( 524) 407 84.7 1.2e-15
>>XP_005270759 (OMIM: 612888) PREDICTED: volume-regulate (803 aa)
initn: 5285 init1: 5285 opt: 5285 Z-score: 5122.3 bits: 958.7 E(85289): 0
Smith-Waterman score: 5285; 100.0% identity (100.0% similar) in 803 aa overlap (1-803:1-803)
10 20 30 40 50 60
pF1KA0 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
730 740 750 760 770 780
790 800
pF1KA0 EENLLNTLPLPVTERLQTCLDKC
:::::::::::::::::::::::
XP_005 EENLLNTLPLPVTERLQTCLDKC
790 800
>>XP_011539448 (OMIM: 612888) PREDICTED: volume-regulate (803 aa)
initn: 5285 init1: 5285 opt: 5285 Z-score: 5122.3 bits: 958.7 E(85289): 0
Smith-Waterman score: 5285; 100.0% identity (100.0% similar) in 803 aa overlap (1-803:1-803)
10 20 30 40 50 60
pF1KA0 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
730 740 750 760 770 780
790 800
pF1KA0 EENLLNTLPLPVTERLQTCLDKC
:::::::::::::::::::::::
XP_011 EENLLNTLPLPVTERLQTCLDKC
790 800
>>XP_011539447 (OMIM: 612888) PREDICTED: volume-regulate (803 aa)
initn: 5285 init1: 5285 opt: 5285 Z-score: 5122.3 bits: 958.7 E(85289): 0
Smith-Waterman score: 5285; 100.0% identity (100.0% similar) in 803 aa overlap (1-803:1-803)
10 20 30 40 50 60
pF1KA0 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
730 740 750 760 770 780
790 800
pF1KA0 EENLLNTLPLPVTERLQTCLDKC
:::::::::::::::::::::::
XP_011 EENLLNTLPLPVTERLQTCLDKC
790 800
>>XP_011539446 (OMIM: 612888) PREDICTED: volume-regulate (803 aa)
initn: 5285 init1: 5285 opt: 5285 Z-score: 5122.3 bits: 958.7 E(85289): 0
Smith-Waterman score: 5285; 100.0% identity (100.0% similar) in 803 aa overlap (1-803:1-803)
10 20 30 40 50 60
pF1KA0 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
730 740 750 760 770 780
790 800
pF1KA0 EENLLNTLPLPVTERLQTCLDKC
:::::::::::::::::::::::
XP_011 EENLLNTLPLPVTERLQTCLDKC
790 800
>>XP_016856373 (OMIM: 612888) PREDICTED: volume-regulate (803 aa)
initn: 5285 init1: 5285 opt: 5285 Z-score: 5122.3 bits: 958.7 E(85289): 0
Smith-Waterman score: 5285; 100.0% identity (100.0% similar) in 803 aa overlap (1-803:1-803)
10 20 30 40 50 60
pF1KA0 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
730 740 750 760 770 780
790 800
pF1KA0 EENLLNTLPLPVTERLQTCLDKC
:::::::::::::::::::::::
XP_016 EENLLNTLPLPVTERLQTCLDKC
790 800
>>XP_016856372 (OMIM: 612888) PREDICTED: volume-regulate (803 aa)
initn: 5285 init1: 5285 opt: 5285 Z-score: 5122.3 bits: 958.7 E(85289): 0
Smith-Waterman score: 5285; 100.0% identity (100.0% similar) in 803 aa overlap (1-803:1-803)
10 20 30 40 50 60
pF1KA0 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
730 740 750 760 770 780
790 800
pF1KA0 EENLLNTLPLPVTERLQTCLDKC
:::::::::::::::::::::::
XP_016 EENLLNTLPLPVTERLQTCLDKC
790 800
>>XP_011539445 (OMIM: 612888) PREDICTED: volume-regulate (803 aa)
initn: 5285 init1: 5285 opt: 5285 Z-score: 5122.3 bits: 958.7 E(85289): 0
Smith-Waterman score: 5285; 100.0% identity (100.0% similar) in 803 aa overlap (1-803:1-803)
10 20 30 40 50 60
pF1KA0 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
730 740 750 760 770 780
790 800
pF1KA0 EENLLNTLPLPVTERLQTCLDKC
:::::::::::::::::::::::
XP_011 EENLLNTLPLPVTERLQTCLDKC
790 800
>>XP_005270758 (OMIM: 612888) PREDICTED: volume-regulate (803 aa)
initn: 5285 init1: 5285 opt: 5285 Z-score: 5122.3 bits: 958.7 E(85289): 0
Smith-Waterman score: 5285; 100.0% identity (100.0% similar) in 803 aa overlap (1-803:1-803)
10 20 30 40 50 60
pF1KA0 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
730 740 750 760 770 780
790 800
pF1KA0 EENLLNTLPLPVTERLQTCLDKC
:::::::::::::::::::::::
XP_005 EENLLNTLPLPVTERLQTCLDKC
790 800
>>XP_005270760 (OMIM: 612888) PREDICTED: volume-regulate (803 aa)
initn: 5285 init1: 5285 opt: 5285 Z-score: 5122.3 bits: 958.7 E(85289): 0
Smith-Waterman score: 5285; 100.0% identity (100.0% similar) in 803 aa overlap (1-803:1-803)
10 20 30 40 50 60
pF1KA0 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
730 740 750 760 770 780
790 800
pF1KA0 EENLLNTLPLPVTERLQTCLDKC
:::::::::::::::::::::::
XP_005 EENLLNTLPLPVTERLQTCLDKC
790 800
>>NP_056165 (OMIM: 612888) volume-regulated anion channe (803 aa)
initn: 5285 init1: 5285 opt: 5285 Z-score: 5122.3 bits: 958.7 E(85289): 0
Smith-Waterman score: 5285; 100.0% identity (100.0% similar) in 803 aa overlap (1-803:1-803)
10 20 30 40 50 60
pF1KA0 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 FPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAEQSVRP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQAKAIFEK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDVQAFTGYK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSKLVKNAQD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIV
730 740 750 760 770 780
790 800
pF1KA0 EENLLNTLPLPVTERLQTCLDKC
:::::::::::::::::::::::
NP_056 EENLLNTLPLPVTERLQTCLDKC
790 800
803 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 18:23:19 2016 done: Wed Nov 2 18:23:21 2016
Total Scan time: 11.410 Total Display time: 0.250
Function used was FASTA [36.3.4 Apr, 2011]