FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0103, 297 aa
  1>>>pF1KA0103 297 - 297 aa - 297 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.8165+/-0.000419; mu= 13.1507+/- 0.026
 mean_var=83.5625+/-17.003, 0's: 0 Z-trim(110.4): 61  B-trim: 65 in 1/51
 Lambda= 0.140303
 statistics sampled from 18651 (18695) to 18651 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.584), E-opt: 0.2 (0.219), width:  16
 Scan time:  6.240

The best scores are:                                      opt bits E(85289)
NP_055488 (OMIM: 607722) ER membrane protein compl ( 297) 1947 404.2 1.6e-112
NP_001316424 (OMIM: 607722) ER membrane protein co ( 298) 1867 388.0 1.2e-107
NP_001316422 (OMIM: 607722) ER membrane protein co ( 306) 1611 336.2 4.9e-92
NP_001316423 (OMIM: 607722) ER membrane protein co ( 212) 1123 237.3   2e-62


>>NP_055488 (OMIM: 607722) ER membrane protein complex s  (297 aa)
 initn: 1947 init1: 1947 opt: 1947  Z-score: 2141.1  bits: 404.2 E(85289): 1.6e-112
Smith-Waterman score: 1947; 100.0% identity (100.0% similar) in 297 aa overlap (1-297:1-297)

               10        20        30        40        50        60
pF1KA0 MAKVSELYDVTWEEMRDKMRKWREENSRNSEQIVEVGEELINEYASKLGDDIWIIYEQVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MAKVSELYDVTWEEMRDKMRKWREENSRNSEQIVEVGEELINEYASKLGDDIWIIYEQVM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 IAALDYGRDDLALFCLQELRRQFPGSHRVKRLTGMRFEAMERYDDAIQLYDRILQEDPTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IAALDYGRDDLALFCLQELRRQFPGSHRVKRLTGMRFEAMERYDDAIQLYDRILQEDPTN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 TAARKRKIAIRKAQGKNVEAIRELNEYLEQFVGDQEAWHELAELYINEHDYAKAAFCLEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TAARKRKIAIRKAQGKNVEAIRELNEYLEQFVGDQEAWHELAELYINEHDYAKAAFCLEE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LMMTNPHNHLYCQQYAEVKYTQGGLENLELSRKYFAQALKLNNRNMRALFGLYMSASHIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LMMTNPHNHLYCQQYAEVKYTQGGLENLELSRKYFAQALKLNNRNMRALFGLYMSASHIA
              190       200       210       220       230       240

              250       260       270       280       290       
pF1KA0 SNPKASAKTKKDNMKYASWAASQINRAYQFAGRSKKETKYSLKAVEDMLETLQITQS
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SNPKASAKTKKDNMKYASWAASQINRAYQFAGRSKKETKYSLKAVEDMLETLQITQS
              250       260       270       280       290       

>>NP_001316424 (OMIM: 607722) ER membrane protein comple  (298 aa)
 initn: 1867 init1: 1867 opt: 1867  Z-score: 2053.6  bits: 388.0 E(85289): 1.2e-107
Smith-Waterman score: 1867; 100.0% identity (100.0% similar) in 285 aa overlap (13-297:14-298)

                10        20        30        40        50         
pF1KA0  MAKVSELYDVTWEEMRDKMRKWREENSRNSEQIVEVGEELINEYASKLGDDIWIIYEQV
                    :::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKYSSSHTLYCLKEEMRDKMRKWREENSRNSEQIVEVGEELINEYASKLGDDIWIIYEQV
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KA0 MIAALDYGRDDLALFCLQELRRQFPGSHRVKRLTGMRFEAMERYDDAIQLYDRILQEDPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIAALDYGRDDLALFCLQELRRQFPGSHRVKRLTGMRFEAMERYDDAIQLYDRILQEDPT
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KA0 NTAARKRKIAIRKAQGKNVEAIRELNEYLEQFVGDQEAWHELAELYINEHDYAKAAFCLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTAARKRKIAIRKAQGKNVEAIRELNEYLEQFVGDQEAWHELAELYINEHDYAKAAFCLE
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KA0 ELMMTNPHNHLYCQQYAEVKYTQGGLENLELSRKYFAQALKLNNRNMRALFGLYMSASHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELMMTNPHNHLYCQQYAEVKYTQGGLENLELSRKYFAQALKLNNRNMRALFGLYMSASHI
              190       200       210       220       230       240

     240       250       260       270       280       290       
pF1KA0 ASNPKASAKTKKDNMKYASWAASQINRAYQFAGRSKKETKYSLKAVEDMLETLQITQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASNPKASAKTKKDNMKYASWAASQINRAYQFAGRSKKETKYSLKAVEDMLETLQITQS
              250       260       270       280       290        

>>NP_001316422 (OMIM: 607722) ER membrane protein comple  (306 aa)
 initn: 1611 init1: 1611 opt: 1611  Z-score: 1773.4  bits: 336.2 E(85289): 4.9e-92
Smith-Waterman score: 1919; 97.1% identity (97.1% similar) in 306 aa overlap (1-297:1-306)

               10        20        30        40        50          
pF1KA0 MAKVSELYDVTWEEMRDKMRKWREENSRNSEQIVEVGEELINEYASKLGDDI--------
       ::::::::::::::::::::::::::::::::::::::::::::::::::::        
NP_001 MAKVSELYDVTWEEMRDKMRKWREENSRNSEQIVEVGEELINEYASKLGDDIFFPLYVYL
               10        20        30        40        50        60

              60        70        80        90       100       110 
pF1KA0 -WIIYEQVMIAALDYGRDDLALFCLQELRRQFPGSHRVKRLTGMRFEAMERYDDAIQLYD
        :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VWIIYEQVMIAALDYGRDDLALFCLQELRRQFPGSHRVKRLTGMRFEAMERYDDAIQLYD
               70        80        90       100       110       120

             120       130       140       150       160       170 
pF1KA0 RILQEDPTNTAARKRKIAIRKAQGKNVEAIRELNEYLEQFVGDQEAWHELAELYINEHDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RILQEDPTNTAARKRKIAIRKAQGKNVEAIRELNEYLEQFVGDQEAWHELAELYINEHDY
              130       140       150       160       170       180

             180       190       200       210       220       230 
pF1KA0 AKAAFCLEELMMTNPHNHLYCQQYAEVKYTQGGLENLELSRKYFAQALKLNNRNMRALFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKAAFCLEELMMTNPHNHLYCQQYAEVKYTQGGLENLELSRKYFAQALKLNNRNMRALFG
              190       200       210       220       230       240

             240       250       260       270       280       290 
pF1KA0 LYMSASHIASNPKASAKTKKDNMKYASWAASQINRAYQFAGRSKKETKYSLKAVEDMLET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYMSASHIASNPKASAKTKKDNMKYASWAASQINRAYQFAGRSKKETKYSLKAVEDMLET
              250       260       270       280       290       300

             
pF1KA0 LQITQS
       ::::::
NP_001 LQITQS
             

>>NP_001316423 (OMIM: 607722) ER membrane protein comple  (212 aa)
 initn: 1121 init1: 1121 opt: 1123  Z-score: 1241.9  bits: 237.3 E(85289): 2e-62
Smith-Waterman score: 1123; 93.0% identity (96.2% similar) in 185 aa overlap (1-182:1-185)

               10        20        30        40        50        60
pF1KA0 MAKVSELYDVTWEEMRDKMRKWREENSRNSEQIVEVGEELINEYASKLGDDIWIIYEQVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAKVSELYDVTWEEMRDKMRKWREENSRNSEQIVEVGEELINEYASKLGDDIWIIYEQVM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 IAALDYGRDDLALFCLQELRRQFPGSHRVKRLTGMRFEAMERYDDAIQLYDRILQEDPTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAALDYGRDDLALFCLQELRRQFPGSHRVKRLTGMRFEAMERYDDAIQLYDRILQEDPTN
               70        80        90       100       110       120

              130       140       150       160       170          
pF1KA0 TAARKRKIAIRKAQGKNVEAIRELNEYLEQFVGDQEAWHELAELYINEHDY---AKAAFC
       :::::::::::::::::::::::::::::::::::::::::::::::::.    ..: : 
NP_001 TAARKRKIAIRKAQGKNVEAIRELNEYLEQFVGDQEAWHELAELYINEHEIESDSHAHFL
              130       140       150       160       170       180

       180       190       200       210       220       230       
pF1KA0 LEELMMTNPHNHLYCQQYAEVKYTQGGLENLELSRKYFAQALKLNNRNMRALFGLYMSAS
       ..: .                                                       
NP_001 VHEYLTLFSYYKQLMRNRMKTFVYCLWSIYIM                            
              190       200       210                              




297 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 18:05:14 2016 done: Wed Nov  2 18:05:15 2016
 Total Scan time:  6.240 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]