Result of FASTA (omim) for
pF1KA0090
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0090, 992 aa
1>>>pF1KA0090 992 - 992 aa - 992 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1849+/-0.000469; mu= 16.3963+/- 0.029
mean_var=71.7888+/-14.457, 0's: 0 Z-trim(109.0): 30 B-trim: 0 in 0/50
Lambda= 0.151372
statistics sampled from 17166 (17174) to 17166 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.538), E-opt: 0.2 (0.201), width: 16
Scan time: 11.340
The best scores are: opt bits E(85289)
NP_001258356 (OMIM: 616846,616875) ER membrane pro ( 992) 6507 1431.2 0
NP_055862 (OMIM: 616846,616875) ER membrane protei ( 993) 6495 1428.6 0
XP_005245845 (OMIM: 616846,616875) PREDICTED: ER m ( 995) 6491 1427.7 0
XP_005245844 (OMIM: 616846,616875) PREDICTED: ER m ( 996) 6479 1425.1 0
NP_001258357 (OMIM: 616846,616875) ER membrane pro ( 992) 6478 1424.8 0
NP_001258358 (OMIM: 616846,616875) ER membrane pro ( 971) 5854 1288.6 0
>>NP_001258356 (OMIM: 616846,616875) ER membrane protein (992 aa)
initn: 6507 init1: 6507 opt: 6507 Z-score: 7672.6 bits: 1431.2 E(85289): 0
Smith-Waterman score: 6507; 100.0% identity (100.0% similar) in 992 aa overlap (1-992:1-992)
10 20 30 40 50 60
pF1KA0 MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 NVIAALNSRTGEILWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVIAALNSRTGEILWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEVKSSSSEDGSMGSFSEKSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEVKSSSSEDGSMGSFSEKSS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 SKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYRA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 LVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKADGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKADGLL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 GMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVTA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 SGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSSL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 YVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRNVLRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRNVLRQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 LHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVHS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 QGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKKAKGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKKAKGP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 VHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQSYIFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQSYIFP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 SSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPYSPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPYSPD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 VQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKDDYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKDDYD
910 920 930 940 950 960
970 980 990
pF1KA0 YVLISSVLFGLVFATMITKRLAQVKLLNRAWR
::::::::::::::::::::::::::::::::
NP_001 YVLISSVLFGLVFATMITKRLAQVKLLNRAWR
970 980 990
>>NP_055862 (OMIM: 616846,616875) ER membrane protein co (993 aa)
initn: 4231 init1: 4231 opt: 6495 Z-score: 7658.5 bits: 1428.6 E(85289): 0
Smith-Waterman score: 6495; 99.9% identity (99.9% similar) in 993 aa overlap (1-992:1-993)
10 20 30 40 50 60
pF1KA0 MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 NVIAALNSRTGEILWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NVIAALNSRTGEILWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY
250 260 270 280 290 300
310 320 330 340 350
pF1KA0 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEV-KSSSSEDGSMGSFSEKS
:::::::::::::::::::::::::::::::::::::::::: :::::::::::::::::
NP_055 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEVQKSSSSEDGSMGSFSEKS
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA0 SSKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SSKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYR
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA0 ALVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKADGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ALVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKADGL
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA0 LGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVT
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA0 ASGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ASGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSS
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA0 LYVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRNVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LYVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRNVLR
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA0 QLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVH
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA0 SQGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKKAKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SQGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKKAKG
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA0 PVHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQSYIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PVHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQSYIF
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA0 PSSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPYSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PSSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPYSP
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA0 DVQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKDDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DVQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKDDY
910 920 930 940 950 960
960 970 980 990
pF1KA0 DYVLISSVLFGLVFATMITKRLAQVKLLNRAWR
:::::::::::::::::::::::::::::::::
NP_055 DYVLISSVLFGLVFATMITKRLAQVKLLNRAWR
970 980 990
>>XP_005245845 (OMIM: 616846,616875) PREDICTED: ER membr (995 aa)
initn: 6493 init1: 3387 opt: 6491 Z-score: 7653.7 bits: 1427.7 E(85289): 0
Smith-Waterman score: 6491; 99.7% identity (99.7% similar) in 995 aa overlap (1-992:1-995)
10 20 30 40 50 60
pF1KA0 MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 NVIAALNSRTGEILWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NVIAALNSRTGEILWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEVKSSSSEDGSMGSFSEKSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEVKSSSSEDGSMGSFSEKSS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 SKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYRA
370 380 390 400 410 420
430 440 450 460 470
pF1KA0 LVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKA---D
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
XP_005 LVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKAAIQD
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA0 GLLGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLLGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVM
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA0 VTASGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTASGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGM
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA0 SSLYVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSLYVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRNV
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA0 LRQLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRQLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEH
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA0 VHSQGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VHSQGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKKA
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA0 KGPVHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KGPVHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQSY
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA0 IFPSSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IFPSSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPY
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA0 SPDVQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPDVQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKD
910 920 930 940 950 960
960 970 980 990
pF1KA0 DYDYVLISSVLFGLVFATMITKRLAQVKLLNRAWR
:::::::::::::::::::::::::::::::::::
XP_005 DYDYVLISSVLFGLVFATMITKRLAQVKLLNRAWR
970 980 990
>>XP_005245844 (OMIM: 616846,616875) PREDICTED: ER membr (996 aa)
initn: 5667 init1: 3387 opt: 6479 Z-score: 7639.5 bits: 1425.1 E(85289): 0
Smith-Waterman score: 6479; 99.6% identity (99.6% similar) in 996 aa overlap (1-992:1-996)
10 20 30 40 50 60
pF1KA0 MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 NVIAALNSRTGEILWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NVIAALNSRTGEILWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY
250 260 270 280 290 300
310 320 330 340 350
pF1KA0 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEV-KSSSSEDGSMGSFSEKS
:::::::::::::::::::::::::::::::::::::::::: :::::::::::::::::
XP_005 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEVQKSSSSEDGSMGSFSEKS
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA0 SSKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYR
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA0 ALVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKA---
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKAAIQ
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA0 DGLLGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DGLLGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMV
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA0 MVTASGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVTASGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESG
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA0 MSSLYVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSSLYVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRN
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA0 VLRQLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLRQLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSE
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA0 HVHSQGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HVHSQGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKK
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA0 AKGPVHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKGPVHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQS
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA0 YIFPSSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YIFPSSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIP
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA0 YSPDVQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YSPDVQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLK
910 920 930 940 950 960
960 970 980 990
pF1KA0 DDYDYVLISSVLFGLVFATMITKRLAQVKLLNRAWR
::::::::::::::::::::::::::::::::::::
XP_005 DDYDYVLISSVLFGLVFATMITKRLAQVKLLNRAWR
970 980 990
>>NP_001258357 (OMIM: 616846,616875) ER membrane protein (992 aa)
initn: 5883 init1: 5883 opt: 6478 Z-score: 7638.4 bits: 1424.8 E(85289): 0
Smith-Waterman score: 6478; 99.8% identity (99.8% similar) in 993 aa overlap (1-992:1-992)
10 20 30 40 50 60
pF1KA0 MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 NVIAALNSRTGEILWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVIAALNSRTGEILWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY
250 260 270 280 290 300
310 320 330 340 350
pF1KA0 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEV-KSSSSEDGSMGSFSEKS
:::::::::::::::::::::::::::::::::::::::::: :::::::::::::::::
NP_001 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEVQKSSSSEDGSMGSFSEKS
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA0 SSKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYR
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA0 ALVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKADGL
:::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
NP_001 ALVQTEDHLLLFLQQL-GKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKADGL
430 440 450 460 470
480 490 500 510 520 530
pF1KA0 LGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVT
480 490 500 510 520 530
540 550 560 570 580 590
pF1KA0 ASGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSS
540 550 560 570 580 590
600 610 620 630 640 650
pF1KA0 LYVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRNVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRNVLR
600 610 620 630 640 650
660 670 680 690 700 710
pF1KA0 QLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVH
660 670 680 690 700 710
720 730 740 750 760 770
pF1KA0 SQGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKKAKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKKAKG
720 730 740 750 760 770
780 790 800 810 820 830
pF1KA0 PVHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQSYIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQSYIF
780 790 800 810 820 830
840 850 860 870 880 890
pF1KA0 PSSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPYSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPYSP
840 850 860 870 880 890
900 910 920 930 940 950
pF1KA0 DVQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKDDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKDDY
900 910 920 930 940 950
960 970 980 990
pF1KA0 DYVLISSVLFGLVFATMITKRLAQVKLLNRAWR
:::::::::::::::::::::::::::::::::
NP_001 DYVLISSVLFGLVFATMITKRLAQVKLLNRAWR
960 970 980 990
>>NP_001258358 (OMIM: 616846,616875) ER membrane protein (971 aa)
initn: 4700 init1: 4231 opt: 5854 Z-score: 6902.1 bits: 1288.6 E(85289): 0
Smith-Waterman score: 6279; 97.6% identity (97.6% similar) in 993 aa overlap (1-992:1-971)
10 20 30 40 50 60
pF1KA0 MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 NVIAALNSRTGEILWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWE
::::::::::::: ::::::::::::::::::::::::
NP_001 NVIAALNSRTGEIY----------------------VITVSNGGRIMRSWETNIGGLNWE
70 80 90
130 140 150 160 170 180
pF1KA0 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS
100 110 120 130 140 150
190 200 210 220 230 240
pF1KA0 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP
160 170 180 190 200 210
250 260 270 280 290 300
pF1KA0 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY
220 230 240 250 260 270
310 320 330 340 350
pF1KA0 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEV-KSSSSEDGSMGSFSEKS
:::::::::::::::::::::::::::::::::::::::::: :::::::::::::::::
NP_001 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEVQKSSSSEDGSMGSFSEKS
280 290 300 310 320 330
360 370 380 390 400 410
pF1KA0 SSKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYR
340 350 360 370 380 390
420 430 440 450 460 470
pF1KA0 ALVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKADGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKADGL
400 410 420 430 440 450
480 490 500 510 520 530
pF1KA0 LGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVT
460 470 480 490 500 510
540 550 560 570 580 590
pF1KA0 ASGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSS
520 530 540 550 560 570
600 610 620 630 640 650
pF1KA0 LYVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRNVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRNVLR
580 590 600 610 620 630
660 670 680 690 700 710
pF1KA0 QLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVH
640 650 660 670 680 690
720 730 740 750 760 770
pF1KA0 SQGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKKAKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKKAKG
700 710 720 730 740 750
780 790 800 810 820 830
pF1KA0 PVHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQSYIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQSYIF
760 770 780 790 800 810
840 850 860 870 880 890
pF1KA0 PSSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPYSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPYSP
820 830 840 850 860 870
900 910 920 930 940 950
pF1KA0 DVQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKDDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKDDY
880 890 900 910 920 930
960 970 980 990
pF1KA0 DYVLISSVLFGLVFATMITKRLAQVKLLNRAWR
:::::::::::::::::::::::::::::::::
NP_001 DYVLISSVLFGLVFATMITKRLAQVKLLNRAWR
940 950 960 970
992 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 18:00:56 2016 done: Wed Nov 2 18:00:57 2016
Total Scan time: 11.340 Total Display time: 0.230
Function used was FASTA [36.3.4 Apr, 2011]