Result of FASTA (omim) for
pF1KA0072
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0072, 504 aa
1>>>pF1KA0072 504 - 504 aa - 504 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.2032+/-0.000491; mu= 12.9380+/- 0.030
mean_var=74.9404+/-15.110, 0's: 0 Z-trim(109.0): 20 B-trim: 492 in 1/49
Lambda= 0.148155
statistics sampled from 17126 (17134) to 17126 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.557), E-opt: 0.2 (0.201), width: 16
Scan time: 9.140
The best scores are: opt bits E(85289)
NP_005038 (OMIM: 604452) 26S proteasome non-ATPase ( 504) 3208 695.8 7.7e-200
XP_011517168 (OMIM: 604452) PREDICTED: 26S proteas ( 440) 2659 578.4 1.4e-164
XP_016870416 (OMIM: 604452) PREDICTED: 26S proteas ( 440) 2659 578.4 1.4e-164
NP_001257356 (OMIM: 604452) 26S proteasome non-ATP ( 461) 2080 454.7 2.7e-127
XP_016870417 (OMIM: 604452) PREDICTED: 26S proteas ( 290) 1848 405.0 1.5e-112
>>NP_005038 (OMIM: 604452) 26S proteasome non-ATPase reg (504 aa)
initn: 3208 init1: 3208 opt: 3208 Z-score: 3708.7 bits: 695.8 E(85289): 7.7e-200
Smith-Waterman score: 3208; 100.0% identity (100.0% similar) in 504 aa overlap (1-504:1-504)
10 20 30 40 50 60
pF1KA0 MAAQALALLREVARLEAPLEELRALHSVLQAVPLNELRQQAAELRLGPLFSLLNENHREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MAAQALALLREVARLEAPLEELRALHSVLQAVPLNELRQQAAELRLGPLFSLLNENHREK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 TTLCVSILERLLQAMEPVHVARNLRVDLQRGLIHPDDSVKILTLSQIGRIVENSDAVTEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TTLCVSILERLLQAMEPVHVARNLRVDLQRGLIHPDDSVKILTLSQIGRIVENSDAVTEI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LNNAELLKQIVYCIGGENLSVAKAAIKSLSRISLTQAGLEALFESNLLDDLKSVMKTNDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LNNAELLKQIVYCIGGENLSVAKAAIKSLSRISLTQAGLEALFESNLLDDLKSVMKTNDI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 VRYRVYELIIEISSVSPESLNYCTTSGLVTQLLRELTGEDVLVRATCIEMVTSLAYTHHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VRYRVYELIIEISSVSPESLNYCTTSGLVTQLLRELTGEDVLVRATCIEMVTSLAYTHHG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 RQYLAQEGVIDQISNIIVGADSDPFSSFYLPGFVKFFGNLAVMDSPQQICERYPIFVEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RQYLAQEGVIDQISNIIVGADSDPFSSFYLPGFVKFFGNLAVMDSPQQICERYPIFVEKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 FEMIESQDPTMIGVAVDTVGILGSNVEGKQVLQKTGTRFERLLMRIGHQSKNAPVELKIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FEMIESQDPTMIGVAVDTVGILGSNVEGKQVLQKTGTRFERLLMRIGHQSKNAPVELKIR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 CLDAISSLLYLPPEQQTDDLLRMTESWFSSLSRDPLELFRGISSQPFPELHCAALKVFTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CLDAISSLLYLPPEQQTDDLLRMTESWFSSLSRDPLELFRGISSQPFPELHCAALKVFTA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 IANQPWAQKLMFNSPGFVEYVVDRSVEHDKASKDAKYELVKALANSKTIAEIFGNPNYLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IANQPWAQKLMFNSPGFVEYVVDRSVEHDKASKDAKYELVKALANSKTIAEIFGNPNYLR
430 440 450 460 470 480
490 500
pF1KA0 LRTYLSEGPYYVKPVSTTAVEGAE
::::::::::::::::::::::::
NP_005 LRTYLSEGPYYVKPVSTTAVEGAE
490 500
>>XP_011517168 (OMIM: 604452) PREDICTED: 26S proteasome (440 aa)
initn: 2659 init1: 2659 opt: 2659 Z-score: 3075.5 bits: 578.4 E(85289): 1.4e-164
Smith-Waterman score: 2659; 100.0% identity (100.0% similar) in 419 aa overlap (1-419:1-419)
10 20 30 40 50 60
pF1KA0 MAAQALALLREVARLEAPLEELRALHSVLQAVPLNELRQQAAELRLGPLFSLLNENHREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAQALALLREVARLEAPLEELRALHSVLQAVPLNELRQQAAELRLGPLFSLLNENHREK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 TTLCVSILERLLQAMEPVHVARNLRVDLQRGLIHPDDSVKILTLSQIGRIVENSDAVTEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTLCVSILERLLQAMEPVHVARNLRVDLQRGLIHPDDSVKILTLSQIGRIVENSDAVTEI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LNNAELLKQIVYCIGGENLSVAKAAIKSLSRISLTQAGLEALFESNLLDDLKSVMKTNDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNNAELLKQIVYCIGGENLSVAKAAIKSLSRISLTQAGLEALFESNLLDDLKSVMKTNDI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 VRYRVYELIIEISSVSPESLNYCTTSGLVTQLLRELTGEDVLVRATCIEMVTSLAYTHHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRYRVYELIIEISSVSPESLNYCTTSGLVTQLLRELTGEDVLVRATCIEMVTSLAYTHHG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 RQYLAQEGVIDQISNIIVGADSDPFSSFYLPGFVKFFGNLAVMDSPQQICERYPIFVEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQYLAQEGVIDQISNIIVGADSDPFSSFYLPGFVKFFGNLAVMDSPQQICERYPIFVEKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 FEMIESQDPTMIGVAVDTVGILGSNVEGKQVLQKTGTRFERLLMRIGHQSKNAPVELKIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FEMIESQDPTMIGVAVDTVGILGSNVEGKQVLQKTGTRFERLLMRIGHQSKNAPVELKIR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 CLDAISSLLYLPPEQQTDDLLRMTESWFSSLSRDPLELFRGISSQPFPELHCAALKVFTA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLDAISSLLYLPPEQQTDDLLRMTESWFSSLSRDPLELFRGISSQPFPELHCAALKVFTG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 IANQPWAQKLMFNSPGFVEYVVDRSVEHDKASKDAKYELVKALANSKTIAEIFGNPNYLR
XP_011 RKHLHLEELVGGNQVKNTVE
430 440
>>XP_016870416 (OMIM: 604452) PREDICTED: 26S proteasome (440 aa)
initn: 2659 init1: 2659 opt: 2659 Z-score: 3075.5 bits: 578.4 E(85289): 1.4e-164
Smith-Waterman score: 2659; 100.0% identity (100.0% similar) in 419 aa overlap (1-419:1-419)
10 20 30 40 50 60
pF1KA0 MAAQALALLREVARLEAPLEELRALHSVLQAVPLNELRQQAAELRLGPLFSLLNENHREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAAQALALLREVARLEAPLEELRALHSVLQAVPLNELRQQAAELRLGPLFSLLNENHREK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 TTLCVSILERLLQAMEPVHVARNLRVDLQRGLIHPDDSVKILTLSQIGRIVENSDAVTEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTLCVSILERLLQAMEPVHVARNLRVDLQRGLIHPDDSVKILTLSQIGRIVENSDAVTEI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LNNAELLKQIVYCIGGENLSVAKAAIKSLSRISLTQAGLEALFESNLLDDLKSVMKTNDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNNAELLKQIVYCIGGENLSVAKAAIKSLSRISLTQAGLEALFESNLLDDLKSVMKTNDI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 VRYRVYELIIEISSVSPESLNYCTTSGLVTQLLRELTGEDVLVRATCIEMVTSLAYTHHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRYRVYELIIEISSVSPESLNYCTTSGLVTQLLRELTGEDVLVRATCIEMVTSLAYTHHG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 RQYLAQEGVIDQISNIIVGADSDPFSSFYLPGFVKFFGNLAVMDSPQQICERYPIFVEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQYLAQEGVIDQISNIIVGADSDPFSSFYLPGFVKFFGNLAVMDSPQQICERYPIFVEKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 FEMIESQDPTMIGVAVDTVGILGSNVEGKQVLQKTGTRFERLLMRIGHQSKNAPVELKIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FEMIESQDPTMIGVAVDTVGILGSNVEGKQVLQKTGTRFERLLMRIGHQSKNAPVELKIR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 CLDAISSLLYLPPEQQTDDLLRMTESWFSSLSRDPLELFRGISSQPFPELHCAALKVFTA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLDAISSLLYLPPEQQTDDLLRMTESWFSSLSRDPLELFRGISSQPFPELHCAALKVFTG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 IANQPWAQKLMFNSPGFVEYVVDRSVEHDKASKDAKYELVKALANSKTIAEIFGNPNYLR
XP_016 RKHLHLEELVGGNQVKNTVE
430 440
>>NP_001257356 (OMIM: 604452) 26S proteasome non-ATPase (461 aa)
initn: 2089 init1: 2062 opt: 2080 Z-score: 2406.3 bits: 454.7 E(85289): 2.7e-127
Smith-Waterman score: 2856; 91.5% identity (91.5% similar) in 504 aa overlap (1-504:1-461)
10 20 30 40 50 60
pF1KA0 MAAQALALLREVARLEAPLEELRALHSVLQAVPLNELRQQAAELRLGPLFSLLNENHREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAQALALLREVARLEAPLEELRALHSVLQAVPLNELRQQAAELRLGPLFSLLNENHREK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 TTLCVSILERLLQAMEPVHVARNLRVDLQRGLIHPDDSVKILTLSQIGRIVENSDAVTEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTLCVSILERLLQAMEPVHVARNLRVDLQRGLIHPDDSVKILTLSQIGRIVENSDAVTEI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LNNAELLKQIVYCIGGENLSVAKAAIKSLSRISLTQAGLEALFESNLLDDLKSVMKTNDI
::::::::::::::::::::::::
NP_001 LNNAELLKQIVYCIGGENLSVAKA------------------------------------
130 140
190 200 210 220 230 240
pF1KA0 VRYRVYELIIEISSVSPESLNYCTTSGLVTQLLRELTGEDVLVRATCIEMVTSLAYTHHG
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -------LIIEISSVSPESLNYCTTSGLVTQLLRELTGEDVLVRATCIEMVTSLAYTHHG
150 160 170 180 190
250 260 270 280 290 300
pF1KA0 RQYLAQEGVIDQISNIIVGADSDPFSSFYLPGFVKFFGNLAVMDSPQQICERYPIFVEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQYLAQEGVIDQISNIIVGADSDPFSSFYLPGFVKFFGNLAVMDSPQQICERYPIFVEKV
200 210 220 230 240 250
310 320 330 340 350 360
pF1KA0 FEMIESQDPTMIGVAVDTVGILGSNVEGKQVLQKTGTRFERLLMRIGHQSKNAPVELKIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEMIESQDPTMIGVAVDTVGILGSNVEGKQVLQKTGTRFERLLMRIGHQSKNAPVELKIR
260 270 280 290 300 310
370 380 390 400 410 420
pF1KA0 CLDAISSLLYLPPEQQTDDLLRMTESWFSSLSRDPLELFRGISSQPFPELHCAALKVFTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLDAISSLLYLPPEQQTDDLLRMTESWFSSLSRDPLELFRGISSQPFPELHCAALKVFTA
320 330 340 350 360 370
430 440 450 460 470 480
pF1KA0 IANQPWAQKLMFNSPGFVEYVVDRSVEHDKASKDAKYELVKALANSKTIAEIFGNPNYLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IANQPWAQKLMFNSPGFVEYVVDRSVEHDKASKDAKYELVKALANSKTIAEIFGNPNYLR
380 390 400 410 420 430
490 500
pF1KA0 LRTYLSEGPYYVKPVSTTAVEGAE
::::::::::::::::::::::::
NP_001 LRTYLSEGPYYVKPVSTTAVEGAE
440 450 460
>>XP_016870417 (OMIM: 604452) PREDICTED: 26S proteasome (290 aa)
initn: 1848 init1: 1848 opt: 1848 Z-score: 2141.7 bits: 405.0 E(85289): 1.5e-112
Smith-Waterman score: 1848; 99.6% identity (100.0% similar) in 282 aa overlap (223-504:9-290)
200 210 220 230 240 250
pF1KA0 SSVSPESLNYCTTSGLVTQLLRELTGEDVLVRATCIEMVTSLAYTHHGRQYLAQEGVIDQ
.:::::::::::::::::::::::::::::
XP_016 MTLFDTGCMRATCIEMVTSLAYTHHGRQYLAQEGVIDQ
10 20 30
260 270 280 290 300 310
pF1KA0 ISNIIVGADSDPFSSFYLPGFVKFFGNLAVMDSPQQICERYPIFVEKVFEMIESQDPTMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISNIIVGADSDPFSSFYLPGFVKFFGNLAVMDSPQQICERYPIFVEKVFEMIESQDPTMI
40 50 60 70 80 90
320 330 340 350 360 370
pF1KA0 GVAVDTVGILGSNVEGKQVLQKTGTRFERLLMRIGHQSKNAPVELKIRCLDAISSLLYLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVAVDTVGILGSNVEGKQVLQKTGTRFERLLMRIGHQSKNAPVELKIRCLDAISSLLYLP
100 110 120 130 140 150
380 390 400 410 420 430
pF1KA0 PEQQTDDLLRMTESWFSSLSRDPLELFRGISSQPFPELHCAALKVFTAIANQPWAQKLMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEQQTDDLLRMTESWFSSLSRDPLELFRGISSQPFPELHCAALKVFTAIANQPWAQKLMF
160 170 180 190 200 210
440 450 460 470 480 490
pF1KA0 NSPGFVEYVVDRSVEHDKASKDAKYELVKALANSKTIAEIFGNPNYLRLRTYLSEGPYYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSPGFVEYVVDRSVEHDKASKDAKYELVKALANSKTIAEIFGNPNYLRLRTYLSEGPYYV
220 230 240 250 260 270
500
pF1KA0 KPVSTTAVEGAE
::::::::::::
XP_016 KPVSTTAVEGAE
280 290
504 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 00:25:18 2016 done: Fri Nov 4 00:25:20 2016
Total Scan time: 9.140 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]