Result of FASTA (omim) for
pF1KA0006
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0006, 776 aa
1>>>pF1KA0006 776 - 776 aa - 776 aa
Library: /omim/omim.rfq.tfa
64369986 residues in 92320 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.4376+/-0.000505; mu= 1.0894+/- 0.031
mean_var=325.7198+/-71.186, 0's: 0 Z-trim(117.4): 329 B-trim: 893 in 2/53
Lambda= 0.071064
statistics sampled from 30027 (30480) to 30027 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.678), E-opt: 0.2 (0.33), width: 16
Scan time: 6.570
The best scores are: opt bits E(92320)
NP_004831 (OMIM: 300267) rho guanine nucleotide ex ( 776) 5090 536.9 1.3e-151
XP_011529715 (OMIM: 300267) rho guanine nucleotide ( 780) 5072 535.1 4.7e-151
XP_011529716 (OMIM: 300267) rho guanine nucleotide ( 773) 5005 528.2 5.4e-149
NP_001293106 (OMIM: 300267) rho guanine nucleotide ( 622) 4087 434.0 1e-120
XP_005262556 (OMIM: 300267) rho guanine nucleotide ( 727) 3753 399.8 2.3e-110
XP_011529718 (OMIM: 300267) rho guanine nucleotide ( 649) 3633 387.5 1.1e-106
XP_011529717 (OMIM: 300267) rho guanine nucleotide ( 746) 3633 387.5 1.2e-106
XP_011529714 (OMIM: 300267) rho guanine nucleotide ( 803) 3633 387.6 1.2e-106
XP_016885464 (OMIM: 300267) rho guanine nucleotide ( 807) 3615 385.7 4.4e-106
NP_663788 (OMIM: 605477) rho guanine nucleotide ex ( 782) 2022 222.4 6.3e-57
XP_016876303 (OMIM: 605477) rho guanine nucleotide ( 794) 2022 222.4 6.4e-57
NP_001307781 (OMIM: 605477) rho guanine nucleotide ( 803) 2022 222.4 6.5e-57
XP_006720019 (OMIM: 605477) rho guanine nucleotide ( 815) 2022 222.4 6.5e-57
NP_001340975 (OMIM: 605477) rho guanine nucleotide ( 862) 2022 222.4 6.8e-57
NP_001106983 (OMIM: 605477) rho guanine nucleotide ( 803) 2006 220.8 2e-56
NP_001307782 (OMIM: 605477) rho guanine nucleotide ( 721) 2004 220.5 2.2e-56
XP_016876305 (OMIM: 605477) rho guanine nucleotide ( 733) 2004 220.5 2.2e-56
NP_001106984 (OMIM: 605477) rho guanine nucleotide ( 753) 2003 220.4 2.4e-56
NP_001340976 (OMIM: 605477) rho guanine nucleotide ( 710) 1872 207.0 2.5e-52
XP_016876304 (OMIM: 605477) rho guanine nucleotide ( 743) 1872 207.0 2.6e-52
NP_001340989 (OMIM: 605477) rho guanine nucleotide ( 625) 1867 206.4 3.3e-52
NP_001340988 (OMIM: 605477) rho guanine nucleotide ( 625) 1867 206.4 3.3e-52
NP_001340986 (OMIM: 605477) rho guanine nucleotide ( 625) 1867 206.4 3.3e-52
NP_001317527 (OMIM: 605477) rho guanine nucleotide ( 625) 1867 206.4 3.3e-52
NP_001340985 (OMIM: 605477) rho guanine nucleotide ( 625) 1867 206.4 3.3e-52
NP_001340987 (OMIM: 605477) rho guanine nucleotide ( 625) 1867 206.4 3.3e-52
NP_001317526 (OMIM: 605477) rho guanine nucleotide ( 625) 1867 206.4 3.3e-52
NP_001340981 (OMIM: 605477) rho guanine nucleotide ( 646) 1867 206.4 3.4e-52
NP_001307780 (OMIM: 605477) rho guanine nucleotide ( 646) 1867 206.4 3.4e-52
NP_001106985 (OMIM: 605477) rho guanine nucleotide ( 646) 1867 206.4 3.4e-52
NP_001340982 (OMIM: 605477) rho guanine nucleotide ( 646) 1867 206.4 3.4e-52
NP_003890 (OMIM: 605477) rho guanine nucleotide ex ( 646) 1867 206.4 3.4e-52
XP_024305196 (OMIM: 605477) rho guanine nucleotide ( 658) 1867 206.4 3.4e-52
XP_016876310 (OMIM: 605477) rho guanine nucleotide ( 658) 1867 206.4 3.4e-52
XP_016876308 (OMIM: 605477) rho guanine nucleotide ( 658) 1867 206.4 3.4e-52
NP_001340983 (OMIM: 605477) rho guanine nucleotide ( 658) 1867 206.4 3.4e-52
XP_016876312 (OMIM: 605477) rho guanine nucleotide ( 658) 1867 206.4 3.4e-52
XP_016876311 (OMIM: 605477) rho guanine nucleotide ( 658) 1867 206.4 3.4e-52
XP_016876309 (OMIM: 605477) rho guanine nucleotide ( 658) 1867 206.4 3.4e-52
NP_001340980 (OMIM: 605477) rho guanine nucleotide ( 705) 1867 206.4 3.6e-52
NP_001340978 (OMIM: 605477) rho guanine nucleotide ( 705) 1867 206.4 3.6e-52
NP_001340979 (OMIM: 605477) rho guanine nucleotide ( 705) 1867 206.4 3.6e-52
NP_001340977 (OMIM: 605477) rho guanine nucleotide ( 705) 1867 206.4 3.6e-52
XP_011519435 (OMIM: 605477) rho guanine nucleotide ( 504) 1822 201.7 7e-51
NP_001307783 (OMIM: 605477) rho guanine nucleotide ( 547) 1413 159.8 3.1e-38
NP_001340984 (OMIM: 605477) rho guanine nucleotide ( 627) 1413 159.8 3.4e-38
XP_016876318 (OMIM: 605477) rho guanine nucleotide ( 501) 1125 130.2 2.3e-29
NP_001340990 (OMIM: 605477) rho guanine nucleotide ( 501) 1125 130.2 2.3e-29
XP_016876317 (OMIM: 605477) rho guanine nucleotide ( 534) 1125 130.2 2.4e-29
XP_024305296 (OMIM: 617940) pleckstrin homology do (1219) 367 52.9 1e-05
>>NP_004831 (OMIM: 300267) rho guanine nucleotide exchan (776 aa)
initn: 5090 init1: 5090 opt: 5090 Z-score: 2843.5 bits: 536.9 E(92320): 1.3e-151
Smith-Waterman score: 5090; 100.0% identity (100.0% similar) in 776 aa overlap (1-776:1-776)
10 20 30 40 50 60
pF1KA0 MNPEEQIVTWLISLGVLESPKKTICDPEEFLKSSLKNGVVLCKLINRLMPGSVEKFCLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MNPEEQIVTWLISLGVLESPKKTICDPEEFLKSSLKNGVVLCKLINRLMPGSVEKFCLDP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 QTEADCINNINDFLKGCATLQVEIFDPDDLYSGVNFSKVLSTLLAVNKATEDQLSERPCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QTEADCINNINDFLKGCATLQVEIFDPDDLYSGVNFSKVLSTLLAVNKATEDQLSERPCG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 RSSSLSAANTSQTNPQGAVSSTVSGLQRQSKTVEMTENGSHQLIVKARFNFKQTNEDELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RSSSLSAANTSQTNPQGAVSSTVSGLQRQSKTVEMTENGSHQLIVKARFNFKQTNEDELS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 VCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKSSERPLSPKAVKGFETAPLTKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKSSERPLSPKAVKGFETAPLTKN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 YYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEVTSLLGNFEEVCTFQQTLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEVTSLLGNFEEVCTFQQTLC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 QALEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVNVLTQHSDELEQFMENQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QALEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVNVLTQHSDELEQFMENQG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 ASSPGILILTTNLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIVAFKTLMGQCQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ASSPGILILTTNLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIVAFKTLMGQCQD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 LRKRKQLELQILSEPIQAWEGEDIKNLGNVIFMSQVMVQYGACEEKEERYLMLFSNVLIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LRKRKQLELQILSEPIQAWEGEDIKNLGNVIFMSQVMVQYGACEEKEERYLMLFSNVLIM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 LSASPRMSGFIYQGKIPIAGTVVTRLDEIEGNDCTFEITGNTVERIVVHCNNNQDFQEWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LSASPRMSGFIYQGKIPIAGTVVTRLDEIEGNDCTFEITGNTVERIVVHCNNNQDFQEWL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 EQLNRLIRGPASCSSLSKTSSSSCSAHSSFSSTGQPRGPLEPPQIIKPWSLSCLRPAPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EQLNRLIRGPASCSSLSKTSSSSCSAHSSFSSTGQPRGPLEPPQIIKPWSLSCLRPAPPL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 RPSAALGYKERMSYILKESSKSPKTMKKFLHKRKTERKPSEEEYVIRKSTAALEEDAQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RPSAALGYKERMSYILKESSKSPKTMKKFLHKRKTERKPSEEEYVIRKSTAALEEDAQIL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 KVIEAYCTSANFQQGHGSSTRKDSIPQVLLPEEEKLIIEETRSNGQTIMEEKSLVDTVYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KVIEAYCTSANFQQGHGSSTRKDSIPQVLLPEEEKLIIEETRSNGQTIMEEKSLVDTVYA
670 680 690 700 710 720
730 740 750 760 770
pF1KA0 LKDEVRELKQENKRMKQCLEEELKSRRDLEKLVRRLLKQTDECIRGESSSKTSILP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LKDEVRELKQENKRMKQCLEEELKSRRDLEKLVRRLLKQTDECIRGESSSKTSILP
730 740 750 760 770
>>XP_011529715 (OMIM: 300267) rho guanine nucleotide exc (780 aa)
initn: 3772 init1: 3772 opt: 5072 Z-score: 2833.5 bits: 535.1 E(92320): 4.7e-151
Smith-Waterman score: 5072; 99.5% identity (99.5% similar) in 780 aa overlap (1-776:1-780)
10 20 30 40 50 60
pF1KA0 MNPEEQIVTWLISLGVLESPKKTICDPEEFLKSSLKNGVVLCKLINRLMPGSVEKFCLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNPEEQIVTWLISLGVLESPKKTICDPEEFLKSSLKNGVVLCKLINRLMPGSVEKFCLDP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 QTEADCINNINDFLKGCATLQVEIFDPDDLYSGVNFSKVLSTLLAVNKATEDQLSERPCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QTEADCINNINDFLKGCATLQVEIFDPDDLYSGVNFSKVLSTLLAVNKATEDQLSERPCG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 RSSSLSAANTSQTNPQGAVSSTVSGLQRQSKTVEMTENGSHQLIVKARFNFKQTNEDELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSSSLSAANTSQTNPQGAVSSTVSGLQRQSKTVEMTENGSHQLIVKARFNFKQTNEDELS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 VCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKSSERPLSPKAVKGFETAPLTKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKSSERPLSPKAVKGFETAPLTKN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 YYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEVTSLLGNFEEVCTFQQTLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEVTSLLGNFEEVCTFQQTLC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 QALEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVNVLTQHSDELEQFMENQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QALEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVNVLTQHSDELEQFMENQG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 ASSPGILILTTNLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIVAFKTLMGQCQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASSPGILILTTNLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIVAFKTLMGQCQD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 LRKRKQLELQILSEPIQAWEGEDIKNLGNVIFMSQVMVQYGACEEKEERYLMLFSNVLIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRKRKQLELQILSEPIQAWEGEDIKNLGNVIFMSQVMVQYGACEEKEERYLMLFSNVLIM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 LSASPRMSGFIYQGKIPIAGTVVTRLDEIEGNDCTFEITGNTVERIVVHCNNNQDFQEWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSASPRMSGFIYQGKIPIAGTVVTRLDEIEGNDCTFEITGNTVERIVVHCNNNQDFQEWL
490 500 510 520 530 540
550 560 570 580 590
pF1KA0 EQLNRLIRGPASCSSLSKTSSSSCSAHS----SFSSTGQPRGPLEPPQIIKPWSLSCLRP
:::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
XP_011 EQLNRLIRGPASCSSLSKTSSSSCSAHSTFSQSFSSTGQPRGPLEPPQIIKPWSLSCLRP
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA0 APPLRPSAALGYKERMSYILKESSKSPKTMKKFLHKRKTERKPSEEEYVIRKSTAALEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APPLRPSAALGYKERMSYILKESSKSPKTMKKFLHKRKTERKPSEEEYVIRKSTAALEED
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA0 AQILKVIEAYCTSANFQQGHGSSTRKDSIPQVLLPEEEKLIIEETRSNGQTIMEEKSLVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQILKVIEAYCTSANFQQGHGSSTRKDSIPQVLLPEEEKLIIEETRSNGQTIMEEKSLVD
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA0 TVYALKDEVRELKQENKRMKQCLEEELKSRRDLEKLVRRLLKQTDECIRGESSSKTSILP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVYALKDEVRELKQENKRMKQCLEEELKSRRDLEKLVRRLLKQTDECIRGESSSKTSILP
730 740 750 760 770 780
>>XP_011529716 (OMIM: 300267) rho guanine nucleotide exc (773 aa)
initn: 4749 init1: 3767 opt: 5005 Z-score: 2796.5 bits: 528.2 E(92320): 5.4e-149
Smith-Waterman score: 5005; 98.6% identity (98.6% similar) in 780 aa overlap (1-776:1-773)
10 20 30 40 50 60
pF1KA0 MNPEEQIVTWLISLGVLESPKKTICDPEEFLKSSLKNGVVLCKLINRLMPGSVEKFCLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNPEEQIVTWLISLGVLESPKKTICDPEEFLKSSLKNGVVLCKLINRLMPGSVEKFCLDP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 QTEADCINNINDFLKGCATLQVEIFDPDDLYSGVNFSKVLSTLLAVNKATEDQLSERPCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QTEADCINNINDFLKGCATLQVEIFDPDDLYSGVNFSKVLSTLLAVNKATEDQLSERPCG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 RSSSLSAANTSQTNPQGAVSSTVSGLQRQSKTVEMTENGSHQLIVKARFNFKQTNEDELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSSSLSAANTSQTNPQGAVSSTVSGLQRQSKTVEMTENGSHQLIVKARFNFKQTNEDELS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 VCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKSSERPLSPKAVKGFETAPLTKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKSSERPLSPKAVKGFETAPLTKN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 YYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEVTSLLGNFEEVCTFQQTLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEVTSLLGNFEEVCTFQQTLC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 QALEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVNVLTQHSDELEQFMENQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QALEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVNVLTQHSDELEQFMENQG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 ASSPGILILTTNLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIVAFKTLMGQCQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASSPGILILTTNLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIVAFKTLMGQCQD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 LRKRKQLELQILSEPIQAWEGEDIKNLGNVIFMSQVMVQYGACEEKEERYLMLFSNVLIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRKRKQLELQILSEPIQAWEGEDIKNLGNVIFMSQVMVQYGACEEKEERYLMLFSNVLIM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 LSASPRMSGFIYQGKIPIAGTVVTRLDEIEGNDCTFEITGNTVERIVVHCNNNQDFQEWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSASPRMSGFIYQGKIPIAGTVVTRLDEIEGNDCTFEITGNTVERIVVHCNNNQDFQEWL
490 500 510 520 530 540
550 560 570 580 590
pF1KA0 EQLNRLIRGPASCSSLSKTSSSSCSAHS----SFSSTGQPRGPLEPPQIIKPWSLSCLRP
:::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
XP_011 EQLNRLIRGPASCSSLSKTSSSSCSAHSTFSQSFSSTGQPRGPLEPPQIIKPWSLSCLRP
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA0 APPLRPSAALGYKERMSYILKESSKSPKTMKKFLHKRKTERKPSEEEYVIRKSTAALEED
:::::::::::::: :::::::::::::::::::::::::::::::::::::::
XP_011 APPLRPSAALGYKE-------ESSKSPKTMKKFLHKRKTERKPSEEEYVIRKSTAALEED
610 620 630 640 650
660 670 680 690 700 710
pF1KA0 AQILKVIEAYCTSANFQQGHGSSTRKDSIPQVLLPEEEKLIIEETRSNGQTIMEEKSLVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQILKVIEAYCTSANFQQGHGSSTRKDSIPQVLLPEEEKLIIEETRSNGQTIMEEKSLVD
660 670 680 690 700 710
720 730 740 750 760 770
pF1KA0 TVYALKDEVRELKQENKRMKQCLEEELKSRRDLEKLVRRLLKQTDECIRGESSSKTSILP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVYALKDEVRELKQENKRMKQCLEEELKSRRDLEKLVRRLLKQTDECIRGESSSKTSILP
720 730 740 750 760 770
>>NP_001293106 (OMIM: 300267) rho guanine nucleotide exc (622 aa)
initn: 4087 init1: 4087 opt: 4087 Z-score: 2289.0 bits: 434.0 E(92320): 1e-120
Smith-Waterman score: 4087; 100.0% identity (100.0% similar) in 622 aa overlap (155-776:1-622)
130 140 150 160 170 180
pF1KA0 LSAANTSQTNPQGAVSSTVSGLQRQSKTVEMTENGSHQLIVKARFNFKQTNEDELSVCKG
::::::::::::::::::::::::::::::
NP_001 MTENGSHQLIVKARFNFKQTNEDELSVCKG
10 20 30
190 200 210 220 230 240
pF1KA0 DIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKSSERPLSPKAVKGFETAPLTKNYYTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKSSERPLSPKAVKGFETAPLTKNYYTV
40 50 60 70 80 90
250 260 270 280 290 300
pF1KA0 VLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEVTSLLGNFEEVCTFQQTLCQALE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEVTSLLGNFEEVCTFQQTLCQALE
100 110 120 130 140 150
310 320 330 340 350 360
pF1KA0 ECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVNVLTQHSDELEQFMENQGASSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVNVLTQHSDELEQFMENQGASSP
160 170 180 190 200 210
370 380 390 400 410 420
pF1KA0 GILILTTNLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIVAFKTLMGQCQDLRKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GILILTTNLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIVAFKTLMGQCQDLRKR
220 230 240 250 260 270
430 440 450 460 470 480
pF1KA0 KQLELQILSEPIQAWEGEDIKNLGNVIFMSQVMVQYGACEEKEERYLMLFSNVLIMLSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQLELQILSEPIQAWEGEDIKNLGNVIFMSQVMVQYGACEEKEERYLMLFSNVLIMLSAS
280 290 300 310 320 330
490 500 510 520 530 540
pF1KA0 PRMSGFIYQGKIPIAGTVVTRLDEIEGNDCTFEITGNTVERIVVHCNNNQDFQEWLEQLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRMSGFIYQGKIPIAGTVVTRLDEIEGNDCTFEITGNTVERIVVHCNNNQDFQEWLEQLN
340 350 360 370 380 390
550 560 570 580 590 600
pF1KA0 RLIRGPASCSSLSKTSSSSCSAHSSFSSTGQPRGPLEPPQIIKPWSLSCLRPAPPLRPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLIRGPASCSSLSKTSSSSCSAHSSFSSTGQPRGPLEPPQIIKPWSLSCLRPAPPLRPSA
400 410 420 430 440 450
610 620 630 640 650 660
pF1KA0 ALGYKERMSYILKESSKSPKTMKKFLHKRKTERKPSEEEYVIRKSTAALEEDAQILKVIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALGYKERMSYILKESSKSPKTMKKFLHKRKTERKPSEEEYVIRKSTAALEEDAQILKVIE
460 470 480 490 500 510
670 680 690 700 710 720
pF1KA0 AYCTSANFQQGHGSSTRKDSIPQVLLPEEEKLIIEETRSNGQTIMEEKSLVDTVYALKDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYCTSANFQQGHGSSTRKDSIPQVLLPEEEKLIIEETRSNGQTIMEEKSLVDTVYALKDE
520 530 540 550 560 570
730 740 750 760 770
pF1KA0 VRELKQENKRMKQCLEEELKSRRDLEKLVRRLLKQTDECIRGESSSKTSILP
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRELKQENKRMKQCLEEELKSRRDLEKLVRRLLKQTDECIRGESSSKTSILP
580 590 600 610 620
>>XP_005262556 (OMIM: 300267) rho guanine nucleotide exc (727 aa)
initn: 3753 init1: 3753 opt: 3753 Z-score: 2103.1 bits: 399.8 E(92320): 2.3e-110
Smith-Waterman score: 4637; 93.7% identity (93.7% similar) in 776 aa overlap (1-776:1-727)
10 20 30 40 50 60
pF1KA0 MNPEEQIVTWLISLGVLESPKKTICDPEEFLKSSLKNGVVLCKLINRLMPGSVEKFCLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNPEEQIVTWLISLGVLESPKKTICDPEEFLKSSLKNGVVLCKLINRLMPGSVEKFCLDP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 QTEADCINNINDFLKGCATLQVEIFDPDDLYSGVNFSKVLSTLLAVNKATEDQLSERPCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QTEADCINNINDFLKGCATLQVEIFDPDDLYSGVNFSKVLSTLLAVNKATEDQLSERPCG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 RSSSLSAANTSQTNPQGAVSSTVSGLQRQSKTVEMTENGSHQLIVKARFNFKQTNEDELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSSSLSAANTSQTNPQGAVSSTVSGLQRQSKTVEMTENGSHQLIVKARFNFKQTNEDELS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 VCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKSSERPLSPKAVKGFETAPLTKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKSSERPLSPKAVKGFETAPLTKN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 YYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEVTSLLGNFEEVCTFQQTLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEVTSLLGNFEEVCTFQQTLC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 QALEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVNVLTQHSDELEQFMENQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QALEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVNVLTQHSDELEQFMENQG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 ASSPGILILTTNLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIVAFKTLMGQCQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASSPGILILTTNLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIVAFKTLMGQCQD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 LRKRKQLELQILSEPIQAWEGEDIKNLGNVIFMSQVMVQYGACEEKEERYLMLFSNVLIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRKRKQLELQILSEPIQAWEGEDIKNLGNVIFMSQVMVQYGACEEKEERYLMLFSNVLIM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 LSASPRMSGFIYQGKIPIAGTVVTRLDEIEGNDCTFEITGNTVERIVVHCNNNQDFQEWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSASPRMSGFIYQGKIPIAGTVVTRLDEIEGNDCTFEITGNTVERIVVHCNNNQDFQEWL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 EQLNRLIRGPASCSSLSKTSSSSCSAHSSFSSTGQPRGPLEPPQIIKPWSLSCLRPAPPL
::::::::::::::::::::::::::::
XP_005 EQLNRLIRGPASCSSLSKTSSSSCSAHS--------------------------------
550 560
610 620 630 640 650 660
pF1KA0 RPSAALGYKERMSYILKESSKSPKTMKKFLHKRKTERKPSEEEYVIRKSTAALEEDAQIL
:::::::::::::::::::::::::::::::::::::::::::
XP_005 -----------------ESSKSPKTMKKFLHKRKTERKPSEEEYVIRKSTAALEEDAQIL
570 580 590 600 610
670 680 690 700 710 720
pF1KA0 KVIEAYCTSANFQQGHGSSTRKDSIPQVLLPEEEKLIIEETRSNGQTIMEEKSLVDTVYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KVIEAYCTSANFQQGHGSSTRKDSIPQVLLPEEEKLIIEETRSNGQTIMEEKSLVDTVYA
620 630 640 650 660 670
730 740 750 760 770
pF1KA0 LKDEVRELKQENKRMKQCLEEELKSRRDLEKLVRRLLKQTDECIRGESSSKTSILP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKDEVRELKQENKRMKQCLEEELKSRRDLEKLVRRLLKQTDECIRGESSSKTSILP
680 690 700 710 720
>>XP_011529718 (OMIM: 300267) rho guanine nucleotide exc (649 aa)
initn: 3633 init1: 3633 opt: 3633 Z-score: 2037.2 bits: 387.5 E(92320): 1.1e-106
Smith-Waterman score: 4019; 95.7% identity (95.8% similar) in 649 aa overlap (155-776:1-649)
130 140 150 160 170 180
pF1KA0 LSAANTSQTNPQGAVSSTVSGLQRQSKTVEMTENGSHQLIVKARFNFKQTNEDELSVCKG
::::::::::::::::::::::::::::::
XP_011 MTENGSHQLIVKARFNFKQTNEDELSVCKG
10 20 30
190 200 210 220
pF1KA0 DIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKSSE-----------------------
::::::::::::::::::::::::::::::::::::.
XP_011 DIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKSSDGVSLLLPGLECNGAISAHHNLCL
40 50 60 70 80 90
230 240 250 260 270
pF1KA0 ----RPLSPKAVKGFETAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGSKRPLSPKAVKGFETAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNL
100 110 120 130 140 150
280 290 300 310 320 330
pF1KA0 STVEVTSLLGNFEEVCTFQQTLCQALEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STVEVTSLLGNFEEVCTFQQTLCQALEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCAN
160 170 180 190 200 210
340 350 360 370 380 390
pF1KA0 HPSAVNVLTQHSDELEQFMENQGASSPGILILTTNLSKPFMRLEKYVTLLQELERHMEDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPSAVNVLTQHSDELEQFMENQGASSPGILILTTNLSKPFMRLEKYVTLLQELERHMEDT
220 230 240 250 260 270
400 410 420 430 440 450
pF1KA0 HPDHQDILKAIVAFKTLMGQCQDLRKRKQLELQILSEPIQAWEGEDIKNLGNVIFMSQVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPDHQDILKAIVAFKTLMGQCQDLRKRKQLELQILSEPIQAWEGEDIKNLGNVIFMSQVM
280 290 300 310 320 330
460 470 480 490 500 510
pF1KA0 VQYGACEEKEERYLMLFSNVLIMLSASPRMSGFIYQGKIPIAGTVVTRLDEIEGNDCTFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQYGACEEKEERYLMLFSNVLIMLSASPRMSGFIYQGKIPIAGTVVTRLDEIEGNDCTFE
340 350 360 370 380 390
520 530 540 550 560 570
pF1KA0 ITGNTVERIVVHCNNNQDFQEWLEQLNRLIRGPASCSSLSKTSSSSCSAHSSFSSTGQPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITGNTVERIVVHCNNNQDFQEWLEQLNRLIRGPASCSSLSKTSSSSCSAHSSFSSTGQPR
400 410 420 430 440 450
580 590 600 610 620 630
pF1KA0 GPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKERMSYILKESSKSPKTMKKFLHKRKTER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKERMSYILKESSKSPKTMKKFLHKRKTER
460 470 480 490 500 510
640 650 660 670 680 690
pF1KA0 KPSEEEYVIRKSTAALEEDAQILKVIEAYCTSANFQQGHGSSTRKDSIPQVLLPEEEKLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPSEEEYVIRKSTAALEEDAQILKVIEAYCTSANFQQGHGSSTRKDSIPQVLLPEEEKLI
520 530 540 550 560 570
700 710 720 730 740 750
pF1KA0 IEETRSNGQTIMEEKSLVDTVYALKDEVRELKQENKRMKQCLEEELKSRRDLEKLVRRLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IEETRSNGQTIMEEKSLVDTVYALKDEVRELKQENKRMKQCLEEELKSRRDLEKLVRRLL
580 590 600 610 620 630
760 770
pF1KA0 KQTDECIRGESSSKTSILP
:::::::::::::::::::
XP_011 KQTDECIRGESSSKTSILP
640
>>XP_011529717 (OMIM: 300267) rho guanine nucleotide exc (746 aa)
initn: 3633 init1: 3633 opt: 3633 Z-score: 2036.4 bits: 387.5 E(92320): 1.2e-106
Smith-Waterman score: 4470; 93.8% identity (94.8% similar) in 744 aa overlap (60-776:4-746)
30 40 50 60 70 80
pF1KA0 FLKSSLKNGVVLCKLINRLMPGSVEKFCLDPQTEADCINNINDFLKGCATLQVEIFDPDD
: :: .:. :. .. . :::::::
XP_011 MKSPACEAGLNTNLY-VLHEEVSSKREIFDPDD
10 20 30
90 100 110 120 130 140
pF1KA0 LYSGVNFSKVLSTLLAVNKATEDQLSERPCGRSSSLSAANTSQTNPQGAVSSTVSGLQRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYSGVNFSKVLSTLLAVNKATEDQLSERPCGRSSSLSAANTSQTNPQGAVSSTVSGLQRQ
40 50 60 70 80 90
150 160 170 180 190 200
pF1KA0 SKTVEMTENGSHQLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNGRTGWF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKTVEMTENGSHQLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNGRTGWF
100 110 120 130 140 150
210 220 230 240
pF1KA0 PSNYVREIKSSE---------------------------RPLSPKAVKGFETAPLTKNYY
:::::::::::. :::::::::::::::::::::
XP_011 PSNYVREIKSSDGVSLLLPGLECNGAISAHHNLCLPGSKRPLSPKAVKGFETAPLTKNYY
160 170 180 190 200 210
250 260 270 280 290 300
pF1KA0 TVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEVTSLLGNFEEVCTFQQTLCQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEVTSLLGNFEEVCTFQQTLCQA
220 230 240 250 260 270
310 320 330 340 350 360
pF1KA0 LEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVNVLTQHSDELEQFMENQGAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVNVLTQHSDELEQFMENQGAS
280 290 300 310 320 330
370 380 390 400 410 420
pF1KA0 SPGILILTTNLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIVAFKTLMGQCQDLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPGILILTTNLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIVAFKTLMGQCQDLR
340 350 360 370 380 390
430 440 450 460 470 480
pF1KA0 KRKQLELQILSEPIQAWEGEDIKNLGNVIFMSQVMVQYGACEEKEERYLMLFSNVLIMLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRKQLELQILSEPIQAWEGEDIKNLGNVIFMSQVMVQYGACEEKEERYLMLFSNVLIMLS
400 410 420 430 440 450
490 500 510 520 530 540
pF1KA0 ASPRMSGFIYQGKIPIAGTVVTRLDEIEGNDCTFEITGNTVERIVVHCNNNQDFQEWLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASPRMSGFIYQGKIPIAGTVVTRLDEIEGNDCTFEITGNTVERIVVHCNNNQDFQEWLEQ
460 470 480 490 500 510
550 560 570 580 590 600
pF1KA0 LNRLIRGPASCSSLSKTSSSSCSAHSSFSSTGQPRGPLEPPQIIKPWSLSCLRPAPPLRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNRLIRGPASCSSLSKTSSSSCSAHSSFSSTGQPRGPLEPPQIIKPWSLSCLRPAPPLRP
520 530 540 550 560 570
610 620 630 640 650 660
pF1KA0 SAALGYKERMSYILKESSKSPKTMKKFLHKRKTERKPSEEEYVIRKSTAALEEDAQILKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAALGYKERMSYILKESSKSPKTMKKFLHKRKTERKPSEEEYVIRKSTAALEEDAQILKV
580 590 600 610 620 630
670 680 690 700 710 720
pF1KA0 IEAYCTSANFQQGHGSSTRKDSIPQVLLPEEEKLIIEETRSNGQTIMEEKSLVDTVYALK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IEAYCTSANFQQGHGSSTRKDSIPQVLLPEEEKLIIEETRSNGQTIMEEKSLVDTVYALK
640 650 660 670 680 690
730 740 750 760 770
pF1KA0 DEVRELKQENKRMKQCLEEELKSRRDLEKLVRRLLKQTDECIRGESSSKTSILP
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEVRELKQENKRMKQCLEEELKSRRDLEKLVRRLLKQTDECIRGESSSKTSILP
700 710 720 730 740
>>XP_011529714 (OMIM: 300267) rho guanine nucleotide exc (803 aa)
initn: 3633 init1: 3633 opt: 3633 Z-score: 2036.1 bits: 387.6 E(92320): 1.2e-106
Smith-Waterman score: 5022; 96.5% identity (96.6% similar) in 803 aa overlap (1-776:1-803)
10 20 30 40 50 60
pF1KA0 MNPEEQIVTWLISLGVLESPKKTICDPEEFLKSSLKNGVVLCKLINRLMPGSVEKFCLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNPEEQIVTWLISLGVLESPKKTICDPEEFLKSSLKNGVVLCKLINRLMPGSVEKFCLDP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 QTEADCINNINDFLKGCATLQVEIFDPDDLYSGVNFSKVLSTLLAVNKATEDQLSERPCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QTEADCINNINDFLKGCATLQVEIFDPDDLYSGVNFSKVLSTLLAVNKATEDQLSERPCG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 RSSSLSAANTSQTNPQGAVSSTVSGLQRQSKTVEMTENGSHQLIVKARFNFKQTNEDELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSSSLSAANTSQTNPQGAVSSTVSGLQRQSKTVEMTENGSHQLIVKARFNFKQTNEDELS
130 140 150 160 170 180
190 200 210 220
pF1KA0 VCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKSSE-------------------
::::::::::::::::::::::::::::::::::::::::.
XP_011 VCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKSSDGVSLLLPGLECNGAISAHH
190 200 210 220 230 240
230 240 250 260 270
pF1KA0 --------RPLSPKAVKGFETAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLCLPGSKRPLSPKAVKGFETAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQS
250 260 270 280 290 300
280 290 300 310 320 330
pF1KA0 NNNLSTVEVTSLLGNFEEVCTFQQTLCQALEECSKFPENQHKVGGCLLSLMPHFKSMYLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNNLSTVEVTSLLGNFEEVCTFQQTLCQALEECSKFPENQHKVGGCLLSLMPHFKSMYLA
310 320 330 340 350 360
340 350 360 370 380 390
pF1KA0 YCANHPSAVNVLTQHSDELEQFMENQGASSPGILILTTNLSKPFMRLEKYVTLLQELERH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YCANHPSAVNVLTQHSDELEQFMENQGASSPGILILTTNLSKPFMRLEKYVTLLQELERH
370 380 390 400 410 420
400 410 420 430 440 450
pF1KA0 MEDTHPDHQDILKAIVAFKTLMGQCQDLRKRKQLELQILSEPIQAWEGEDIKNLGNVIFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEDTHPDHQDILKAIVAFKTLMGQCQDLRKRKQLELQILSEPIQAWEGEDIKNLGNVIFM
430 440 450 460 470 480
460 470 480 490 500 510
pF1KA0 SQVMVQYGACEEKEERYLMLFSNVLIMLSASPRMSGFIYQGKIPIAGTVVTRLDEIEGND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQVMVQYGACEEKEERYLMLFSNVLIMLSASPRMSGFIYQGKIPIAGTVVTRLDEIEGND
490 500 510 520 530 540
520 530 540 550 560 570
pF1KA0 CTFEITGNTVERIVVHCNNNQDFQEWLEQLNRLIRGPASCSSLSKTSSSSCSAHSSFSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CTFEITGNTVERIVVHCNNNQDFQEWLEQLNRLIRGPASCSSLSKTSSSSCSAHSSFSST
550 560 570 580 590 600
580 590 600 610 620 630
pF1KA0 GQPRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKERMSYILKESSKSPKTMKKFLHKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQPRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKERMSYILKESSKSPKTMKKFLHKR
610 620 630 640 650 660
640 650 660 670 680 690
pF1KA0 KTERKPSEEEYVIRKSTAALEEDAQILKVIEAYCTSANFQQGHGSSTRKDSIPQVLLPEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTERKPSEEEYVIRKSTAALEEDAQILKVIEAYCTSANFQQGHGSSTRKDSIPQVLLPEE
670 680 690 700 710 720
700 710 720 730 740 750
pF1KA0 EKLIIEETRSNGQTIMEEKSLVDTVYALKDEVRELKQENKRMKQCLEEELKSRRDLEKLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLIIEETRSNGQTIMEEKSLVDTVYALKDEVRELKQENKRMKQCLEEELKSRRDLEKLV
730 740 750 760 770 780
760 770
pF1KA0 RRLLKQTDECIRGESSSKTSILP
:::::::::::::::::::::::
XP_011 RRLLKQTDECIRGESSSKTSILP
790 800
>>XP_016885464 (OMIM: 300267) rho guanine nucleotide exc (807 aa)
initn: 2794 init1: 2315 opt: 3615 Z-score: 2026.1 bits: 385.7 E(92320): 4.4e-106
Smith-Waterman score: 5004; 96.0% identity (96.2% similar) in 807 aa overlap (1-776:1-807)
10 20 30 40 50 60
pF1KA0 MNPEEQIVTWLISLGVLESPKKTICDPEEFLKSSLKNGVVLCKLINRLMPGSVEKFCLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNPEEQIVTWLISLGVLESPKKTICDPEEFLKSSLKNGVVLCKLINRLMPGSVEKFCLDP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 QTEADCINNINDFLKGCATLQVEIFDPDDLYSGVNFSKVLSTLLAVNKATEDQLSERPCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTEADCINNINDFLKGCATLQVEIFDPDDLYSGVNFSKVLSTLLAVNKATEDQLSERPCG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 RSSSLSAANTSQTNPQGAVSSTVSGLQRQSKTVEMTENGSHQLIVKARFNFKQTNEDELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSSSLSAANTSQTNPQGAVSSTVSGLQRQSKTVEMTENGSHQLIVKARFNFKQTNEDELS
130 140 150 160 170 180
190 200 210 220
pF1KA0 VCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKSSE-------------------
::::::::::::::::::::::::::::::::::::::::.
XP_016 VCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKSSDGVSLLLPGLECNGAISAHH
190 200 210 220 230 240
230 240 250 260 270
pF1KA0 --------RPLSPKAVKGFETAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLCLPGSKRPLSPKAVKGFETAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQS
250 260 270 280 290 300
280 290 300 310 320 330
pF1KA0 NNNLSTVEVTSLLGNFEEVCTFQQTLCQALEECSKFPENQHKVGGCLLSLMPHFKSMYLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNNLSTVEVTSLLGNFEEVCTFQQTLCQALEECSKFPENQHKVGGCLLSLMPHFKSMYLA
310 320 330 340 350 360
340 350 360 370 380 390
pF1KA0 YCANHPSAVNVLTQHSDELEQFMENQGASSPGILILTTNLSKPFMRLEKYVTLLQELERH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YCANHPSAVNVLTQHSDELEQFMENQGASSPGILILTTNLSKPFMRLEKYVTLLQELERH
370 380 390 400 410 420
400 410 420 430 440 450
pF1KA0 MEDTHPDHQDILKAIVAFKTLMGQCQDLRKRKQLELQILSEPIQAWEGEDIKNLGNVIFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEDTHPDHQDILKAIVAFKTLMGQCQDLRKRKQLELQILSEPIQAWEGEDIKNLGNVIFM
430 440 450 460 470 480
460 470 480 490 500 510
pF1KA0 SQVMVQYGACEEKEERYLMLFSNVLIMLSASPRMSGFIYQGKIPIAGTVVTRLDEIEGND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQVMVQYGACEEKEERYLMLFSNVLIMLSASPRMSGFIYQGKIPIAGTVVTRLDEIEGND
490 500 510 520 530 540
520 530 540 550 560
pF1KA0 CTFEITGNTVERIVVHCNNNQDFQEWLEQLNRLIRGPASCSSLSKTSSSSCSAHS----S
::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
XP_016 CTFEITGNTVERIVVHCNNNQDFQEWLEQLNRLIRGPASCSSLSKTSSSSCSAHSTFSQS
550 560 570 580 590 600
570 580 590 600 610 620
pF1KA0 FSSTGQPRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKERMSYILKESSKSPKTMKKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSSTGQPRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKERMSYILKESSKSPKTMKKF
610 620 630 640 650 660
630 640 650 660 670 680
pF1KA0 LHKRKTERKPSEEEYVIRKSTAALEEDAQILKVIEAYCTSANFQQGHGSSTRKDSIPQVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHKRKTERKPSEEEYVIRKSTAALEEDAQILKVIEAYCTSANFQQGHGSSTRKDSIPQVL
670 680 690 700 710 720
690 700 710 720 730 740
pF1KA0 LPEEEKLIIEETRSNGQTIMEEKSLVDTVYALKDEVRELKQENKRMKQCLEEELKSRRDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPEEEKLIIEETRSNGQTIMEEKSLVDTVYALKDEVRELKQENKRMKQCLEEELKSRRDL
730 740 750 760 770 780
750 760 770
pF1KA0 EKLVRRLLKQTDECIRGESSSKTSILP
:::::::::::::::::::::::::::
XP_016 EKLVRRLLKQTDECIRGESSSKTSILP
790 800
>>NP_663788 (OMIM: 605477) rho guanine nucleotide exchan (782 aa)
initn: 2796 init1: 1452 opt: 2022 Z-score: 1143.6 bits: 222.4 E(92320): 6.3e-57
Smith-Waterman score: 2770; 59.0% identity (81.6% similar) in 719 aa overlap (1-679:1-712)
10 20 30 40 50 60
pF1KA0 MNPEEQIVTWLISLGVLESPKKTICDPEEFLKSSLKNGVVLCKLINRLMPGSVEKFCLDP
:: :: :::::.::::::::::: ::: ::..:::.:::::.:..::.::..:: .:
NP_663 MNSAEQTVTWLITLGVLESPKKTISDPEGFLQASLKDGVVLCRLLERLLPGTIEKVYPEP
10 20 30 40 50 60
70 80 90 100 110
pF1KA0 QTEADCINNINDFLKGC-ATLQVEIFDPDDLYSGVNFSKVLSTLLAVNKATED--QLSER
..:..:..:: .::.:: :.:..: :: .:::.: ::.::::.:...::.: : :.
NP_663 RSESECLSNIREFLRGCGASLRLETFDANDLYQGQNFNKVLSSLVTLNKVTADIGLGSDS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KA0 PCGRSSSLSAANTSQTNPQGAVSSTVSGLQRQSKTVEMTENGSHQLIVKARFNFKQTNED
:.: :: . .. . :. . : . .: : ....::.:...::.:.:.:::.:::::
NP_663 VCARPSSHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNED
130 140 150 160 170 180
180 190 200 210 220 230
pF1KA0 ELSVCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKSSERPLSPKA------VKG
::: :::.:.::::::::::::::::::::::::::::.:.::.:.:::. ::
NP_663 ELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYVREVKASEKPVSPKSGTLKSPPKG
190 200 210 220 230 240
240 250 260 270 280 290
pF1KA0 FETAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEVTSLLGNFEE
:.:. ..:.::.:::::::.::.::.::::..: :::::::....::..... :.::.::
NP_663 FDTTAINKSYYNVVLQNILETENEYSKELQTVLSTYLRPLQTSEKLSSANISYLMGNLEE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KA0 VCTFQQTLCQALEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVNVLTQHSDE
.:.::: : :.::::.:.:: :..::::.:.:::..:..::.:::::::::::::.::.:
NP_663 ICSFQQMLVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVNVLTEHSEE
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA0 LEQFMENQGASSPGILILTTNLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIVAF
: .:::..::::::::.:::.::::::::.:: :::.:::::::: : :.::: :...::
NP_663 LGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDRQDIQKSMAAF
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA0 KTLMGQCQDLRKRKQLELQILSEPIQAWEGEDIKNLGNVIFMSQVMVQYGACEEKEERYL
:.: .:::..::::.::::::.: :. :::.:::.:::: .::::..: .. :::.::::
NP_663 KNLSAQCQEVRKRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYL
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA0 MLFSNVLIMLSASPRMSGFIYQGKIPIAGTVVTRLDEIEGNDCTFEITGNTVERIVVHCN
.:: :::.::::::::::::::::.: .: ..:.:.. :.. .:::.:. .:::.: ::
NP_663 LLFPNVLLMLSASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCN
490 500 510 520 530 540
540 550 560
pF1KA0 NNQDFQEWLEQLNRLIR----G--------------------PASCSSLSKTSSSSCSAH
:.::.:::.:.:.. . : :.: . :: . . . :
NP_663 NQQDLQEWVEHLQKQTKVTSVGNPTIKPHSVPSHTLPSHPVTPSSKHADSKPAPLTPAYH
550 560 570 580 590 600
570 580 590 600 610 620
pF1KA0 S--SFSSTGQPR-----GPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKERMSYILKESS
. : : :. ::::::. :::::::::::::::::::: ::: .:
NP_663 TLPHPSHHGTPHTTINWGPLEPPKTPKPWSLSCLRPAPPLRPSAALCYKEDLS-------
610 620 630 640 650
630 640 650 660 670 680
pF1KA0 KSPKTMKKFLHKRKTERKPSEEEYVIRKSTAALEEDAQILKVIEAYCTSANFQQGHGSST
::::::::.: ::: :::::.::.. ::::::::::::::::::::::::. .: .:.
NP_663 KSPKTMKKLLPKRKPERKPSDEEFASRKSTAALEEDAQILKVIEAYCTSAKTRQTLNSTW
660 670 680 690 700 710
690 700 710 720 730 740
pF1KA0 RKDSIPQVLLPEEEKLIIEETRSNGQTIMEEKSLVDTVYALKDEVRELKQENKRMKQCLE
NP_663 QGTDLMHNHVLADDDQPSLDSLGRRSSLSRLEPSDLSEDSDYDSIWTAHSYRMGSTSRKS
720 730 740 750 760 770
776 residues in 1 query sequences
64369986 residues in 92320 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Oct 24 21:58:08 2019 done: Thu Oct 24 21:58:09 2019
Total Scan time: 6.570 Total Display time: 0.180
Function used was FASTA [36.3.4 Apr, 2011]