Gene/Protein Characteristic Table for
FHC02069
Species
human
Product ID
FHC02069
Linker Type
Cloning Site
SgfI-PmeI
Gene
KIBB2260
Description
discoidin domain receptor tyrosine kinase 1
Original Clone ID
fk11093
Characterization of the cloned ORF
N-terminal HaloTag-fusions expressed in HEK293 visualized by HaloTag TMR ligand
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Length: 2628 bp
Restriction map A
Restriction map B
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Length: 876 aa
Result of homology search against nr database (
FASTA output,
Multiple alignment)
Entry Exp ID% Protein Source CAA52915 0 100.0 TrkE [Homo sapi... Homo sapiens AAP36894 0 100.0 discoidin domai... synthetic construct AAQ02613 0 100.0 discoidin domai... synthetic construct BAE06103 0 100.0 DDR1 variant pr... Homo sapiens AAH70070 0 99.7 DDR1 protein [H... Homo sapiens
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
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Result of InterProScan
Search method interpro_ID From To Entry Definition BlastProDom IPR000719 579 861 PD000001 Protein kinase FPrintScan IPR001245 664 677 PR00109 Tyrosine protein kinase IPR001245 719 737 PR00109 Tyrosine protein kinase IPR001245 768 778 PR00109 Tyrosine protein kinase IPR001245 787 809 PR00109 Tyrosine protein kinase HMMPfam IPR000421 46 182 PF00754 Coagulation factor 5/8 type IPR001245 573 868 PF07714 Tyrosine protein kinase HMMSmart IPR000421 30 185 SM00231 Coagulation factor 5/8 type IPR001245 573 868 SM00219 Tyrosine protein kinase IPR002290 573 868 SM00220 Serine/threonine protein kinase ProfileScan IPR000421 31 185 PS50022 Coagulation factor 5/8 type IPR000719 573 868 PS50011 Protein kinase ScanRegExp IPR000421 72 104 PS01285 Coagulation factor 5/8 type IPR000421 168 185 PS01286 Coagulation factor 5/8 type IPR008266 725 737 PS00109 Tyrosine protein kinase IPR002011 753 761 PS00239 Receptor tyrosine kinase
Prediction of transmembrane (TM) segments
Method No. N terminal transmembrane region C terminal type length SOSUI2 1 1 MGPEALSSLLLLLLVASG 18 SECONDARY 18 2 416 TAILIGCLVAIILLLLLIIALML 438 PRIMARY 23
Result of homology search against disease genes in OMIM database
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%) NP_001945 876 600408 100.0 100.0 NP_054699 913 600408 95.9 100.0 NP_054700 919 600408 95.3 100.0 NP_006173 855 191311 75.8 98.9 NP_001014796 855 191311 75.8 98.9 Inquiries or Suggestions ?
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