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SpecieshumanProduct IDFXC11615Cloning SiteSgfI-PmeIGeneKIBB3463SymbolRAPGEF6
Alias : KIA001LB, PDZ-GEF2, PDZGEF2, RA-GEF-2, RAGEF2DescriptionRap guanine nucleotide exchange factor (GEF) 6, transcript variant 2Original Clone IDha02566
Length: 4803 bp
Restriction map A
Restriction map B
Genomic Structure
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Length: 1601 aa
Result of homology search against CCDS protein database (
FASTA output,
Multiple alignment)
Entry Exp ID% symbol CCDS34225.1 0 99.9 RAPGEF6 CCDS54900.1 0 99.4 RAPGEF6 CCDS54899.1 0 99.4 RAPGEF6 CCDS54898.1 0 99.1 RAPGEF6 CCDS54901.1 0 99.0 RAPGEF6
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
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Result of InterProScan
Search method interpro_ID From To Entry Definition HMMPfam IPR000595 303 381 PF00027 Cyclic nucleotide-binding domain IPR000651 416 502 PF00618 Ras-like guanine nucleotide exchange factor IPR001478 531 608 PF00595 PDZ/DHR/GLGF IPR000159 751 833 PF00788 Ras-association IPR001895 857 1042 PF00617 Guanine-nucleotide dissociation stimulator CDC25 HMMSmart IPR000595 280 398 SM00100 Cyclic nucleotide-binding domain IPR000651 412 525 SM00229 Ras-like guanine nucleotide exchange factor IPR001478 540 612 SM00228 PDZ/DHR/GLGF IPR000159 749 835 SM00314 Ras-association IPR001895 856 1138 SM00147 Guanine-nucleotide dissociation stimulator CDC25 ProfileScan IPR000595 280 380 PS50042 Cyclic nucleotide-binding domain IPR000651 412 526 PS50212 Ras-like guanine nucleotide exchange factor IPR001478 530 600 PS50106 PDZ/DHR/GLGF IPR000159 749 835 PS50200 Ras-association IPR001895 860 1088 PS50009 Guanine-nucleotide dissociation stimulator CDC25
Result of homology search against disease genes in OMIM database(FASTA output,
Multiple alignment)
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%) NP_057424 1601 610499 99.9 100.0 NP_001157858 1609 610499 99.4 100.0 NP_001157860 1504 610499 99.4 92.9 NP_001157859 1509 610499 99.0 92.9 XP_005263416 1693 609530 63.5 97.1 Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.comCloned ORF Nucleotide sequence for pF1KB3463 Download>KIBB3463 4803 bp ATGAACTCACCCGTGGACCCTGGCGCTAGGCAGGCGTTGAGGAAGAAGCCACCCGAGCGG ACTCCCGAGGACTTAAATACTATTTATTCTTATCTTCATGGAATGGAAATATTATCAAAT CTCAGGGAACATCAGCTTAGATTAATGTCTGCAAGAGCACGCTATGAGAGATACAGTGGC AATCAGGTTCTCTTTTGTTCAGAAACGATTGCCAGATGTTGGTATATCCTACTTTCTGGA TCTGTGCTTGTGAAAGGCTCCATGGTCTTGCCTCCTTGCAGTTTTGGTAAGCAGTTTGGA GGAAAAAGAGGATGTGATTGTCTTGTATTAGAGCCTTCAGAAATGATTGTGGTAGAGAAT GCCAAAGATAATGAAGATAGTATTCTACAAAGAGAAATTCCTGCCAGACAATCCCGAAGA AGATTTCGGAAAATTAACTATAAAGGAGAGCGCCAAACCATTACTGATGATGTGGAGGTT AACAGCTATCTTTCTCTTCCAGCTGATCTTACCAAGATGCATCTCACAGAAAACCCTCAT CCACAGGTGACTCATGTGTCTTCTAGTCAGTCTGGTTGTAGCATTGCCAGTGACTCTGGA AGCAGCAGTTTATCTGATATCTATCAGGCTACGGAGAGTGAGGTAGGAGATGTAGATTTG ACACGTCTTCCAGAAGGACCTGTTGATTCTGAGGATGACGAAGAGGAAGATGAAGAGATT GATCGAACAGATCCATTGCAGGGGCGAGATCTTGTTCGAGAATGTCTTGAAAAAGAACCT GCAGACAAAACTGATGATGACATTGAACAATTGCTGGAGTTTATGCACCAGCTCCCTGCA TTTGCAAACATGACCATGTCTGTAAGGAGAGAACTCTGCTCAGTGATGATTTTTGAAGTG GTAGAGCAGGCTGGAGCTATTATTCTTGAAGATGGGCAAGAGCTTGACTCATGGTATGTT ATTTTAAACGGCACTGTGGAAATCAGTCATCCAGATGGAAAAGTTGAAAATTTGTTTATG GGAAATAGTTTTGGAATTACTCCCACTCTGGATAAGCAGTACATGCATGGAATTGTCAGG ACTAAAGTAGATGATTGTCAGTTTGTCTGCATAGCCCAGCAAGATTATTGGAGAATTTTA AACCATGTGGAAAAAAATACCCATAAAGTTGAGGAAGAGGGAGAAATCGTTATGGTACAT GAGCATCGGGAACTAGACCGGAGTGGAACCAGGAAAGGACACATTGTGATCAAGGCAACA CCTGAGCGTCTCATAATGCATTTAATAGAAGAACATTCCATCGTGGATCCAACTTATATA GAAGATTTTCTATTAACTTACAGGACATTTCTTGAAAGTCCTTTGGATGTTGGGATCAAA CTATTGGAATGGTTTAAGATCGACAGCTTAAGAGATAAGGTGACACGGATTGTATTATTA TGGGTAAATAATCATTTTAATGATTTTGAAGGTGACCCTGCTATGACTCGATTTCTAGAG GAATTTGAAAAAAATCTGGAAGATACAAAGATGAATGGTCATCTCCGGTTATTGAATATT GCCTGTGCTGCAAAGGCTAAGTGGAGACAGGTTGTGCTGCAAAAGGCTTCCCGCGAGTCC CCTCTACAATTCAGCCTTAATGGAGGGAGTGAGAAGGGATTTGGTATTTTTGTTGAAGGA GTAGAACCTGGTAGCAAAGCTGCTGATTCAGGACTGAAACGTGGTGATCAGATTATGGAA GTAAATGGACAAAACTTTGAGAATATTACATTTATGAAAGCCGTTGAAATTTTGAGGAAT AATACTCATCTTGCACTTACTGTGAAGACCAACATTTTTGTGTTCAAAGAGTTACTTTTT AGGACTGAACAAGAGAAATCTGGTGTTCCTCATATTCCCAAAATTGCTGAAAAAAAAAGT AATCGCCATTCTATCCAGCATGTGCCAGGAGATATTGAACAGACATCACAGGAGAAAGGA AGTAAGAAAGTTAAAGCAAATACTGTTTCAGGTGGAAGAAACAAAATCAGGAAGATTTTG GATAAAACACGATTTAGTATCTTGCCTCCAAAGCTATTTAGTGATGGAGGCCTAAGCCAA TCACAAGATGACAGCATTGTGGGAACAAGGCACTGTAGGCATAGTCTGGCTATAATGCCC ATCCCTGGAACACTCTCATCCAGCAGCCCTGATCTCCTGCAGCCTACCACCAGTATGTTG GATTTCTCCAATCCTTCAGATATCCCTGATCAAGTTATAAGAGTTTTCAAAGTGGATCAG CAAAGTTGCTACATTATCATCAGTAAAGACACCACAGCTAAAGAAGTAGTTTTTCATGCT GTTCATGAATTTGGTTTGACCGGTGCATCCGACACATATTCTCTCTGTGAAGTTTCTGTT ACTCCTGAGGGTGTCATAAAACAGAGAAGACTTCCAGATCAGTTCTCCAAATTAGCTGAT AGAATTCAACTCAATGGAAGGTATTACTTAAAAAATAACATGGAAACAGAAACCTTATGT TCAGATGAAGATGCTCAAGAACTAGTTAAGGAAAGCCAGCTATCCATGCTGCAGCTCAGT ACCATTGAGGTGGCCACCCAGCTGTCAATGAGGGACTTTGATTTGTTTCGTAATATTGAA CCGACTGAGTACATCGATGACCTTTTTAAGTTAAATTCCAAAACAGGAAATACTCATTTG AAGAGGTTTGAGGACATTGTAAACCAAGAGACATTCTGGGTTGCCTCAGAAATTTTAACT GAAGCAAATCAGCTCAAACGAATGAAGATTATTAAGCATTTTATTAAAATTGCACTTCAT TGTCGAGAATGTAAGAACTTCAATTCCATGTTTGCAATAATAAGTGGCTTGAACCTGGCA TCTGTAGCAAGACTCAGAGGAACTTGGGAAAAGTTACCAAGCAAATACGAGAAACATCTT CAAGATCTACAAGACATTTTTGATCCATCTAGAAACATGGCAAAGTATAGAAATATTCTT AGTAGTCAAAGTATGCAGCCTCCAATTATTCCACTCTTCCCTGTTGTCAAGAAAGATATG ACATTTCTACATGAAGGAAATGACTCCAAAGTAGATGGTTTAGTAAACTTTGAGAAGTTA AGAATGATTTCCAAGGAAATCCGCCAAGTTGTTCGAATGACTTCTGCTAACATGGACCCA GCTATGATGTTTCGACAGAGGTCACTGAGTCAAGGAAGCACAAATTCAAACATGCTGGAT GTTCAGGGAGGTGCTCACAAAAAAAGGGCACGCCGCAGCTCTCTGCTTAATGCCAAGAAG CTATATGAGGATGCCCAAATGGCAAGGAAGGTGAAGCAGTATCTTTCCAGTCTCGATGTA GAGACAGATGAGGAGAAGTTCCAGATGATGTCATTACAGTGGGAGCCTGCATATGGTACC TTGACCAAGAATTTAAGTGAGAAAAGATCAGCCAAATCATCTGAAATGTCTCCAGTGCCT ATGAGGTCAGCTGGCCAAACAACTAAAGCCCACTTGCATCAACCCCACAGAGTAAGCCAG GTGCTTCAGGTGCCAGCTGTTAATTTGCACCCCATCAGGAAGAAGGGACAAACAAAAGAC CCTGCACTGAATACAAGTTTACCTCAGAAAGTTTTAGGAACAACTGAAGAAATAAGTGGT AAGAAGCATACAGAAGACACTATTTCTGTGGCGTCATCTTTACATTCTAGTCCTCCTGCA TCTCCTCAAGGCTCCCCTCACAAAGGTTACACACTTATTCCATCAGCTAAATCTGACAAC TTGTCTGACTCCAGCCATAGTGAGATTTCTTCACGGTCCAGCATCGTGAGCAATTGTTCT GTTGACTCCATGTCTGCAGCTCTACAGGATGAACGGTGTTCCTCTCAGGCCCTGGCAGTC CCTGAATCCACTGGGGCATTGGAAAAGACAGAGCACGCTTCAGGGATAGGAGATCATAGT CAACATGGCCCTGGGTGGACACTCTTGAAGCCATCTCTAATCAAGTGTTTAGCTGTCTCA TCGTCTGTGAGCAATGAAGAGATTTCTCAAGAGCATATCATTATAGAAGCAGCTGACAGT GGTCGTGGAAGTTGGACTTCGTGTTCAAGCAGCTCCCATGACAACTTCCAAAGCCTTCCA AACCCAAAAAGCTGGGATTTTTTGAACTCTTACAGACATACCCATTTGGATGACCCCATT GCTGAAGTTGAACCCACTGACTCTGAGCCCTATTCCTGTTCTAAAAGCTGCTCTAGAACT TGTGGGCAGTGTAAAGGAAGCCTAGAGAGAAAGAGTTGGACCTCCTCCAGTTCTCTGTCT GACACGTATGAACCAAACTATGGGACAGTTAAACGGAGAGTATTGGAGAGCACCCCAGCT GAGTCATCTGAAGGCTTGGACCCCAAGGATGCCACTGACCCAGTTTATAAAACTGTCACT TCAAGTACAGAAAAGGGCTTGATTGTGTACTGTGTCACCTCACCCAAGAAGGACGATAGG TATAGGGAGCCACCTCCCACTCCTCCAGGATATTTGGGGATTTCTTTAGCGGACCTAAAG GAAGGACCCCACACACACCTAAAACCTCCAGATTATAGTGTGGCAGTGCAGAGGTCAAAG ATGATGCATAACAGCCTCTCTAGACTGCCACCAGCTTCTCTCAGTAGCAACCTCGTGGCC TGTGTTCCATCGAAGATTGTAACTCAGCCTCAGAGGCATAATTTGCAGCCATTCCATCCT AAACTAGGAGATGTGACTGATGCAGATAGCGAAGCAGATGAAAATGAACAAGTTTCAGCA GTC
Cloned ORF protein sequence for pF1KB3463 Download>KIBB3463 1601 aa MNSPVDPGARQALRKKPPERTPEDLNTIYSYLHGMEILSNLREHQLRLMSARARYERYSG NQVLFCSETIARCWYILLSGSVLVKGSMVLPPCSFGKQFGGKRGCDCLVLEPSEMIVVEN AKDNEDSILQREIPARQSRRRFRKINYKGERQTITDDVEVNSYLSLPADLTKMHLTENPH PQVTHVSSSQSGCSIASDSGSSSLSDIYQATESEVGDVDLTRLPEGPVDSEDDEEEDEEI DRTDPLQGRDLVRECLEKEPADKTDDDIEQLLEFMHQLPAFANMTMSVRRELCSVMIFEV VEQAGAIILEDGQELDSWYVILNGTVEISHPDGKVENLFMGNSFGITPTLDKQYMHGIVR TKVDDCQFVCIAQQDYWRILNHVEKNTHKVEEEGEIVMVHEHRELDRSGTRKGHIVIKAT PERLIMHLIEEHSIVDPTYIEDFLLTYRTFLESPLDVGIKLLEWFKIDSLRDKVTRIVLL WVNNHFNDFEGDPAMTRFLEEFEKNLEDTKMNGHLRLLNIACAAKAKWRQVVLQKASRES PLQFSLNGGSEKGFGIFVEGVEPGSKAADSGLKRGDQIMEVNGQNFENITFMKAVEILRN NTHLALTVKTNIFVFKELLFRTEQEKSGVPHIPKIAEKKSNRHSIQHVPGDIEQTSQEKG SKKVKANTVSGGRNKIRKILDKTRFSILPPKLFSDGGLSQSQDDSIVGTRHCRHSLAIMP IPGTLSSSSPDLLQPTTSMLDFSNPSDIPDQVIRVFKVDQQSCYIIISKDTTAKEVVFHA VHEFGLTGASDTYSLCEVSVTPEGVIKQRRLPDQFSKLADRIQLNGRYYLKNNMETETLC SDEDAQELVKESQLSMLQLSTIEVATQLSMRDFDLFRNIEPTEYIDDLFKLNSKTGNTHL KRFEDIVNQETFWVASEILTEANQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLA SVARLRGTWEKLPSKYEKHLQDLQDIFDPSRNMAKYRNILSSQSMQPPIIPLFPVVKKDM TFLHEGNDSKVDGLVNFEKLRMISKEIRQVVRMTSANMDPAMMFRQRSLSQGSTNSNMLD VQGGAHKKRARRSSLLNAKKLYEDAQMARKVKQYLSSLDVETDEEKFQMMSLQWEPAYGT LTKNLSEKRSAKSSEMSPVPMRSAGQTTKAHLHQPHRVSQVLQVPAVNLHPIRKKGQTKD PALNTSLPQKVLGTTEEISGKKHTEDTISVASSLHSSPPASPQGSPHKGYTLIPSAKSDN LSDSSHSEISSRSSIVSNCSVDSMSAALQDERCSSQALAVPESTGALEKTEHASGIGDHS QHGPGWTLLKPSLIKCLAVSSSVSNEEISQEHIIIEAADSGRGSWTSCSSSSHDNFQSLP NPKSWDFLNSYRHTHLDDPIAEVEPTDSEPYSCSKSCSRTCGQCKGSLERKSWTSSSSLS DTYEPNYGTVKRRVLESTPAESSEGLDPKDATDPVYKTVTSSTEKGLIVYCVTSPKKDDR YREPPPTPPGYLGISLADLKEGPHTHLKPPDYSVAVQRSKMMHNSLSRLPPASLSSNLVA CVPSKIVTQPQRHNLQPFHPKLGDVTDADSEADENEQVSAV
Nucleotide Sequence (with vector) for pF1KB3463 Download>pF1KB3463 7916 bp GGATCTCGATCCCGCGAAATTAATACGACTCACTATAGGGGAATTGTGAGCGGATAACAA TTCCCCACTAGTAATAATTTTCTTTAACTTTAGTAAGGAGCGATCGCCATGAACTCACCC GTGGACCCTGGCGCTAGGCAGGCGTTGAGGAAGAAGCCACCCGAGCGGACTCCCGAGGAC TTAAATACTATTTATTCTTATCTTCATGGAATGGAAATATTATCAAATCTCAGGGAACAT CAGCTTAGATTAATGTCTGCAAGAGCACGCTATGAGAGATACAGTGGCAATCAGGTTCTC TTTTGTTCAGAAACGATTGCCAGATGTTGGTATATCCTACTTTCTGGATCTGTGCTTGTG AAAGGCTCCATGGTCTTGCCTCCTTGCAGTTTTGGTAAGCAGTTTGGAGGAAAAAGAGGA TGTGATTGTCTTGTATTAGAGCCTTCAGAAATGATTGTGGTAGAGAATGCCAAAGATAAT GAAGATAGTATTCTACAAAGAGAAATTCCTGCCAGACAATCCCGAAGAAGATTTCGGAAA ATTAACTATAAAGGAGAGCGCCAAACCATTACTGATGATGTGGAGGTTAACAGCTATCTT TCTCTTCCAGCTGATCTTACCAAGATGCATCTCACAGAAAACCCTCATCCACAGGTGACT CATGTGTCTTCTAGTCAGTCTGGTTGTAGCATTGCCAGTGACTCTGGAAGCAGCAGTTTA TCTGATATCTATCAGGCTACGGAGAGTGAGGTAGGAGATGTAGATTTGACACGTCTTCCA GAAGGACCTGTTGATTCTGAGGATGACGAAGAGGAAGATGAAGAGATTGATCGAACAGAT CCATTGCAGGGGCGAGATCTTGTTCGAGAATGTCTTGAAAAAGAACCTGCAGACAAAACT GATGATGACATTGAACAATTGCTGGAGTTTATGCACCAGCTCCCTGCATTTGCAAACATG ACCATGTCTGTAAGGAGAGAACTCTGCTCAGTGATGATTTTTGAAGTGGTAGAGCAGGCT GGAGCTATTATTCTTGAAGATGGGCAAGAGCTTGACTCATGGTATGTTATTTTAAACGGC ACTGTGGAAATCAGTCATCCAGATGGAAAAGTTGAAAATTTGTTTATGGGAAATAGTTTT GGAATTACTCCCACTCTGGATAAGCAGTACATGCATGGAATTGTCAGGACTAAAGTAGAT GATTGTCAGTTTGTCTGCATAGCCCAGCAAGATTATTGGAGAATTTTAAACCATGTGGAA AAAAATACCCATAAAGTTGAGGAAGAGGGAGAAATCGTTATGGTACATGAGCATCGGGAA CTAGACCGGAGTGGAACCAGGAAAGGACACATTGTGATCAAGGCAACACCTGAGCGTCTC ATAATGCATTTAATAGAAGAACATTCCATCGTGGATCCAACTTATATAGAAGATTTTCTA TTAACTTACAGGACATTTCTTGAAAGTCCTTTGGATGTTGGGATCAAACTATTGGAATGG TTTAAGATCGACAGCTTAAGAGATAAGGTGACACGGATTGTATTATTATGGGTAAATAAT CATTTTAATGATTTTGAAGGTGACCCTGCTATGACTCGATTTCTAGAGGAATTTGAAAAA AATCTGGAAGATACAAAGATGAATGGTCATCTCCGGTTATTGAATATTGCCTGTGCTGCA AAGGCTAAGTGGAGACAGGTTGTGCTGCAAAAGGCTTCCCGCGAGTCCCCTCTACAATTC AGCCTTAATGGAGGGAGTGAGAAGGGATTTGGTATTTTTGTTGAAGGAGTAGAACCTGGT AGCAAAGCTGCTGATTCAGGACTGAAACGTGGTGATCAGATTATGGAAGTAAATGGACAA AACTTTGAGAATATTACATTTATGAAAGCCGTTGAAATTTTGAGGAATAATACTCATCTT GCACTTACTGTGAAGACCAACATTTTTGTGTTCAAAGAGTTACTTTTTAGGACTGAACAA GAGAAATCTGGTGTTCCTCATATTCCCAAAATTGCTGAAAAAAAAAGTAATCGCCATTCT ATCCAGCATGTGCCAGGAGATATTGAACAGACATCACAGGAGAAAGGAAGTAAGAAAGTT AAAGCAAATACTGTTTCAGGTGGAAGAAACAAAATCAGGAAGATTTTGGATAAAACACGA TTTAGTATCTTGCCTCCAAAGCTATTTAGTGATGGAGGCCTAAGCCAATCACAAGATGAC AGCATTGTGGGAACAAGGCACTGTAGGCATAGTCTGGCTATAATGCCCATCCCTGGAACA CTCTCATCCAGCAGCCCTGATCTCCTGCAGCCTACCACCAGTATGTTGGATTTCTCCAAT CCTTCAGATATCCCTGATCAAGTTATAAGAGTTTTCAAAGTGGATCAGCAAAGTTGCTAC ATTATCATCAGTAAAGACACCACAGCTAAAGAAGTAGTTTTTCATGCTGTTCATGAATTT GGTTTGACCGGTGCATCCGACACATATTCTCTCTGTGAAGTTTCTGTTACTCCTGAGGGT GTCATAAAACAGAGAAGACTTCCAGATCAGTTCTCCAAATTAGCTGATAGAATTCAACTC AATGGAAGGTATTACTTAAAAAATAACATGGAAACAGAAACCTTATGTTCAGATGAAGAT GCTCAAGAACTAGTTAAGGAAAGCCAGCTATCCATGCTGCAGCTCAGTACCATTGAGGTG GCCACCCAGCTGTCAATGAGGGACTTTGATTTGTTTCGTAATATTGAACCGACTGAGTAC ATCGATGACCTTTTTAAGTTAAATTCCAAAACAGGAAATACTCATTTGAAGAGGTTTGAG GACATTGTAAACCAAGAGACATTCTGGGTTGCCTCAGAAATTTTAACTGAAGCAAATCAG CTCAAACGAATGAAGATTATTAAGCATTTTATTAAAATTGCACTTCATTGTCGAGAATGT AAGAACTTCAATTCCATGTTTGCAATAATAAGTGGCTTGAACCTGGCATCTGTAGCAAGA CTCAGAGGAACTTGGGAAAAGTTACCAAGCAAATACGAGAAACATCTTCAAGATCTACAA GACATTTTTGATCCATCTAGAAACATGGCAAAGTATAGAAATATTCTTAGTAGTCAAAGT ATGCAGCCTCCAATTATTCCACTCTTCCCTGTTGTCAAGAAAGATATGACATTTCTACAT GAAGGAAATGACTCCAAAGTAGATGGTTTAGTAAACTTTGAGAAGTTAAGAATGATTTCC AAGGAAATCCGCCAAGTTGTTCGAATGACTTCTGCTAACATGGACCCAGCTATGATGTTT CGACAGAGGTCACTGAGTCAAGGAAGCACAAATTCAAACATGCTGGATGTTCAGGGAGGT GCTCACAAAAAAAGGGCACGCCGCAGCTCTCTGCTTAATGCCAAGAAGCTATATGAGGAT GCCCAAATGGCAAGGAAGGTGAAGCAGTATCTTTCCAGTCTCGATGTAGAGACAGATGAG GAGAAGTTCCAGATGATGTCATTACAGTGGGAGCCTGCATATGGTACCTTGACCAAGAAT TTAAGTGAGAAAAGATCAGCCAAATCATCTGAAATGTCTCCAGTGCCTATGAGGTCAGCT GGCCAAACAACTAAAGCCCACTTGCATCAACCCCACAGAGTAAGCCAGGTGCTTCAGGTG CCAGCTGTTAATTTGCACCCCATCAGGAAGAAGGGACAAACAAAAGACCCTGCACTGAAT ACAAGTTTACCTCAGAAAGTTTTAGGAACAACTGAAGAAATAAGTGGTAAGAAGCATACA GAAGACACTATTTCTGTGGCGTCATCTTTACATTCTAGTCCTCCTGCATCTCCTCAAGGC TCCCCTCACAAAGGTTACACACTTATTCCATCAGCTAAATCTGACAACTTGTCTGACTCC AGCCATAGTGAGATTTCTTCACGGTCCAGCATCGTGAGCAATTGTTCTGTTGACTCCATG TCTGCAGCTCTACAGGATGAACGGTGTTCCTCTCAGGCCCTGGCAGTCCCTGAATCCACT GGGGCATTGGAAAAGACAGAGCACGCTTCAGGGATAGGAGATCATAGTCAACATGGCCCT GGGTGGACACTCTTGAAGCCATCTCTAATCAAGTGTTTAGCTGTCTCATCGTCTGTGAGC AATGAAGAGATTTCTCAAGAGCATATCATTATAGAAGCAGCTGACAGTGGTCGTGGAAGT TGGACTTCGTGTTCAAGCAGCTCCCATGACAACTTCCAAAGCCTTCCAAACCCAAAAAGC TGGGATTTTTTGAACTCTTACAGACATACCCATTTGGATGACCCCATTGCTGAAGTTGAA CCCACTGACTCTGAGCCCTATTCCTGTTCTAAAAGCTGCTCTAGAACTTGTGGGCAGTGT AAAGGAAGCCTAGAGAGAAAGAGTTGGACCTCCTCCAGTTCTCTGTCTGACACGTATGAA CCAAACTATGGGACAGTTAAACGGAGAGTATTGGAGAGCACCCCAGCTGAGTCATCTGAA GGCTTGGACCCCAAGGATGCCACTGACCCAGTTTATAAAACTGTCACTTCAAGTACAGAA AAGGGCTTGATTGTGTACTGTGTCACCTCACCCAAGAAGGACGATAGGTATAGGGAGCCA CCTCCCACTCCTCCAGGATATTTGGGGATTTCTTTAGCGGACCTAAAGGAAGGACCCCAC ACACACCTAAAACCTCCAGATTATAGTGTGGCAGTGCAGAGGTCAAAGATGATGCATAAC AGCCTCTCTAGACTGCCACCAGCTTCTCTCAGTAGCAACCTCGTGGCCTGTGTTCCATCG AAGATTGTAACTCAGCCTCAGAGGCATAATTTGCAGCCATTCCATCCTAAACTAGGAGAT GTGACTGATGCAGATAGCGAAGCAGATGAAAATGAACAAGTTTCAGCAGTCGTTTAAACG AATTCGAGCTCGGTACCCGGGGATCCTCTAGAGTCGACCTGCAGGCATGCAAGCTGATCC GGCTGCTAACAAAGCCCGAAAGGAAGCTGAGTTGGCTGCTGCCACCGCTGAGCAATAACT AGCATAACCCCTTGGGGCCTCTAAACGGGTCTTGAGGGGTTTTTTGCTGAAAGGAGGAAC TATATCCGGTTCGCTTGCTGTCCATAAAACCGCCCAGTCTAGCTATCGCCATGTAAGCCC ACTGCAAGCTACCTGCTTTCTCTTTGCGCTTGCGTTTTCCCTTGTCCAGATAGCCCAGTA GCTGACATTCATCCGGGGTCAGCACCGTTTCTGCGGACTGGCTTTCTACGTGTTCCGCTT CCTTTAGCAGCCCTTGCGCCCTGAGTGCTTGCGGCAGCGTGAGCTTCAAAAGAATTGCCA GCTGGGGCGCCCTCTGGTAAGGTTGGGAAGCCCTGCAAAGTAAACTGGATGGCTTTCTTG CCGCCAAGGATCTGATGGCGCAGGGGATCAAGATCTGATCAAGAGACAGGATGACGGTCG TTTCGCATGCTTGAACAAGATGGATTGCACGCAGGTTCTCCGGCCGCTTGGGTGGAGAGG CTATTCGGCTATGACTGGGCACAACAGACAATCGGCTGCTCTGATGCCGCCGTGTTCCGG CTGTCAGCGCAGGGGCGCCCGGTTCTTTTTGTCAAGACCGACCTGTCCGGTGCCCTGAAT GAACTGCAGGACGAGGCAGCGCGGCTATCGTGGCTGGCCACGACGGGCGTTCCTTGCGCA GCTGTGCTCGACGTTGTCACTGAAGCGGGAAGGGACTGGCTGCTATTGGGCGAAGTGCCG GGGCAGGATCTCCTGTCATCTCACCTTGCTCCTGCCGAGAAAGTATCCATCATGGCTGAT GCAATGCGGCGGCTGCATACGCTTGATCCGGCTACCTGCCCATTCGACCACCAAGCGAAA CATCGCATCGAGCGAGCACGCACTCGGATGGAAGCCGGTCTTGTCGATCAGGATGATCTG GACGAAGAGCATCAGGGGCTCGCGCCAGCCGAACTGTTCGCCAGGCTCAAGGCGCGTATG CCGGATGGTGAGGATCTCGTCGTGACTCATGGCGATGCCTGCTTGCCGAATATCATGGTG GAAAATGGCCGCTTTTCTGGATTCATCGACTGTGGCCGGCTGGGTGTGGCGGACCGCTAT CAGGACATAGCGTTGGCTACCCGTGATATTGCTGAAGAGCTTGGCGGCGAATGGGCTGAC CGCTTCCTCGTGCTTTACGGTATCGCCGCTCCCGATTCGCAGCGCATCGCCTTCTATCGC CTTCTTGACGAGTTCTTCTGAGCGGGACTCTGGGGTTCGAAATGACCGACCAAGCGACGC CCAACCGGACTATAAAAGGATCTAGGTGAAGATCCTTTTTGATAATCTCATGACCAAAAT CCCTTAACGTGAGTTTTCGTTCCACTGAGCGTCAGACCCCGTAGAAAAGATCAAAGGATC TTCTTGAAATCCTTTTTTTCTGCGCGTAATCTGCTGCTTGCAAACAAAAAAACCACCGCT ACCAGCGGTGGTTTGTTTGCCGGATCAAGAGCTACCAACTCTTTTTCCGAAGGTAACTGG CTTCAGCAGAGCGCAGATACCAAATACTGTCCTTCTAGTGTAGCCGTAGTTAGGCCACCA CTTCAAGAACTCTGTAGCACCGCCTACATACCTCGCTCTGCTAATCCTGTTACCAGTGGC TGCTGCCAGTGGCGATAAGTCGTGTCTTACCGGGTTGGACTCAAGACGATAGTTACCGGA TAAGGCGCAGCGGTCGGGCTGAACGGGGGGTTCGTGCACACAGCCCAGCTTGGAGCGAAC GACCTACACCGAACTGAGATACCTACAGCGTGAGCTATGAGAAAGCGCCACGCTTCCCGA AGGGAGAAAGGCGGACAGGTATCCGGTAAGCGGCAGGGTCGGAACAGGAGAGCGCACGAG GGAGCTTCCAGGGGGAAACGCCTGGTATCTTTATAGTCCTGTCGGGTTTCGCCACCTCTG ACTTGAGCGTCGATTTTTGTGATGCTCGTCAGGGGGGCGGAGCCTATGGAAAAACGCCAG CAACGCGGCCTTTTTACGGTTCCTGGCCTTTTGCTGGCCTTTTGCTCACATGTTCTTTCC TGCGTTATCCCCTGATTCTGTGGATAACCGTATTACCGCCTTTGAGTGAGCTGATACCGG AAATACAGGAACGCACGCTGGATGGCCCTTCGCTGGGATGGTGAAACCATGAAAAATGGC AGCTTCAGTGGATTAAGTGGGGGTAATGTGGCCTGTACCCTCTGGTTGCATAGGTATTCA TACGGTTAAAATTTATCAGGCGCGATTGCGGCAGTTTTTCGGGTGGTTTGTTGCCATTTT TACCTGTCTGCTGCCGTGATCGCGCTGAACGCGTTTTAGCGGTGCGTACAATTAAGGGAT TATGGTAAATCCACTTACTGTCTGCCCTCGTAGCCATCGAGATAAACCGCAGTACTCCGG CCACGATGCGTCCGGCGTAGAGGATCGAGATCTTTTCAGCCTGATACAGATTAAATCAGA ACGCAGAAGCGGTCTGATAAAACAGAATTTGCCTGGCGGCAGTAGCGCGGTGGTCCCACC TGACCCCATGCCGAACTCAGAAGTGAAACGCCGTAGCGCCGATGGTAGTGTGGGGTCTCC CCATGCGAGAGTAGGGAACTGCCAGGCATCAAATAAAACGAAAGGCTCAGTCGAAAGACT GGGCCTTTCGTTTTATCTGTTGTTTGTCGGTGAACGCTCTCCTGAGTAGGACAAATCCGC CGGGAGCGGATTTGAACGTTGCGAAGCAACGGCCCGGAGGGTGGCGGGCAGGACGCCCGC CATAAACTGCCAGGCATCAAATTAAGCAGAAGGCCATCCTGACGGATGGCCTTTTTGCGT TTCTACAAACTCTTTTGTTTATTTTTCTAAATACATTCAAATATGTATCCGCTCAT
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