Gene/Protein Characteristic Table for FXC03047

Species
human

Product ID
FXC03047

Corresponding
HaloTag Clone PID

ORF Sequence
DNA sequence (1245 bp)
Protein sequence (415 aa)

Linker Type
Flexi type
The extra Val codon is attached to the 3'-end of the ORF, because a Pme I site ...

Cloning Site
SgfI-PmeI

GenBank Accession
ORF sequence is derived from [AB464487]

Gene
KIBB8825

Symbol
CXCR3
Alias : CD182, CD183, CKR-L2, CMKAR3, GPR9, IP10-R, Mig-R, MigR

Description
chemokine (C-X-C motif) receptor 3

Original Clone ID
cp00860

Features of the cloned ORF sequence

Length: 1245 bp
Restriction map A Restriction map B
Genomic Structure
Features of the protein sequence

Length: 415 aa
Result of homology search against nr database ( FASTA output, Multiple alignment)
Entry Exp ID% Protein Source
NP_001136269 1.2e-181 100.0 C-X-C chemokine...
Homo sapiens
CAB02143 3.7e-181 99.8 G PROTEIN-COUPL...
Homo sapiens
XP_003281930 6.4e-180 99.0 c-X-C chemokine...
Nomascus leucogenys
EHH60983 2.7e-179 98.6 hypothetical pr...
Macaca fascicularis
XP_003917914 1.9e-178 98.1 c-X-C chemokine...
Papio anubis

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
[ zoom out (x2) ] PR01532 PR01532 PR01532 PR00657 PR00237 PR01532 PR00237 PR00657 PR00657 PR00237 PR01532 PR00237 PR01532 PR01532 PR00237 PR00237 PR01532 PR00657 PR00237 PR00657 PR01532 PF00001 PS50262 PS00237

Result of InterProScan

Search method interpro_ID From To Entry Definition
FPrintScan IPR004070 50 69 PR01532 C-X-C chemokine receptor
IPR004070 72 83 PR01532 C-X-C chemokine receptor
IPR004070 87 100 PR01532 C-X-C chemokine receptor
IPR000355 90 108 PR00657 Chemokine receptor
IPR000276 102 126 PR00237 Rhodopsin-like GPCR superfamily
IPR004070 126 137 PR01532 C-X-C chemokine receptor
IPR000276 135 156 PR00237 Rhodopsin-like GPCR superfamily
IPR000355 149 159 PR00657 Chemokine receptor
IPR000355 175 188 PR00657 Chemokine receptor
IPR000276 178 200 PR00237 Rhodopsin-like GPCR superfamily
IPR004070 199 211 PR01532 C-X-C chemokine receptor
IPR000276 214 235 PR00237 Rhodopsin-like GPCR superfamily
IPR004070 223 238 PR01532 C-X-C chemokine receptor
IPR004070 251 263 PR01532 C-X-C chemokine receptor
IPR000276 263 286 PR00237 Rhodopsin-like GPCR superfamily
IPR000276 300 324 PR00237 Rhodopsin-like GPCR superfamily
IPR004070 338 354 PR01532 C-X-C chemokine receptor
IPR000355 343 357 PR00657 Chemokine receptor
IPR000276 347 373 PR00237 Rhodopsin-like GPCR superfamily
IPR000355 367 381 PR00657 Chemokine receptor
IPR004070 399 414 PR01532 C-X-C chemokine receptor
HMMPfam IPR000276 117 365 PF00001 Rhodopsin-like GPCR superfamily
ProfileScan IPR000276 117 365 PS50262 Rhodopsin-like GPCR superfamily
ScanRegExp IPR000276 184 200 PS00237 Rhodopsin-like GPCR superfamily

Prediction of transmembrane (TM) segments
Method No. N terminal transmembrane region C terminal type length
SOSUI2 1 104 PALYSLLFLLGLLGNGAVAAVLL 126 PRIMARY 23
2 137 TFLLHLAVADTLLVLTLPLWAVD 159 PRIMARY 23
3 171 CKVAGALFNINFYAGALLLACIS 193 PRIMARY 23
4 215 VTLTCLAVWGLCLLFALPDFIFL 237 PRIMARY 23
5 264 VLQLVAGFLLPLLVMAYCYAHIL 286 PRIMARY 23
6 307 VVVAFALCWTPYHLVVLVDILMD 329 PRIMARY 23

Result of homology search against disease genes in OMIM database
(FASTA output, Multiple alignment)
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%)
NP_001495 368 300574 100.0 88.0
NP_001707 372 601613 68.3 83.1
NP_001548 360 146928 68.5 81.2
NP_001829 378 600242 70.2 81.2
NP_001008540 356 162643,193670 68.3 83.4
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