Gene/Protein Characteristic Table for FXC01350

Species
human

Product ID
FXC01350

Corresponding
HaloTag Clone PID

ORF Sequence
DNA sequence (1887 bp)
Protein sequence (629 aa)

Linker Type
Flexi type
The extra Val codon is attached to the 3'-end of the ORF, because a Pme I site ...

Cloning Site
SgfI-PmeI

GenBank Accession
ORF sequence is derived from [AB384881]

Gene
KIBB3975

Symbol
DYRK1B
Alias : MIRK

Description
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B

Original Clone ID
fj09226

Features of the cloned ORF sequence

Length: 1887 bp
Restriction map A Restriction map B
Genomic Structure
Features of the protein sequence

Length: 629 aa
Result of homology search against nr database ( FASTA output, Multiple alignment)
Entry Exp ID% Protein Source
NP_004705 9.7e-157 100.0 dual specificit...
Homo sapiens
BAG52042 1.5e-156 99.8 unnamed protein...
Homo sapiens
XP_003915574 4.3e-156 99.5 dual specificit...
Papio anubis
XP_003915576 4.6e-156 99.5 dual specificit...
Papio anubis
XP_003943192 6.1e-156 99.7 dual specificit...
Saimiri bolivie...

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
[ zoom out (x2) ] PD000001 PF00069 SM00219 SM00220 PS50011 PS00107 PS00108

Result of InterProScan

Search method interpro_ID From To Entry Definition
BlastProDom IPR000719 111 327 PD000001 Protein kinase
HMMPfam IPR000719 111 431 PF00069 Protein kinase
HMMSmart IPR001245 111 357 SM00219 Tyrosine protein kinase
IPR002290 111 431 SM00220 Serine/threonine protein kinase
ProfileScan IPR000719 111 431 PS50011 Protein kinase
ScanRegExp IPR000719 117 140 PS00107 Protein kinase
IPR008271 235 247 PS00108 Serine/threonine protein kinase

Result of homology search against disease genes in OMIM database
(FASTA output, Multiple alignment)
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%)
NP_004705 629 604556 100.0 100.0
NP_006475 601 604556 95.5 100.0
NP_001387 763 600855 86.9 84.1
NP_569120 754 600855 87.0 82.5
NP_006474 589 604556 93.6 100.0
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