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SpecieshumanProduct IDFXC01663Cloning SiteSgfI-PmeISymbolTOPBP1
Alias : Dpb11, TOP2BP1Descriptiontopoisomerase (DNA) II binding protein 1
Length: 4566 bp
Restriction map A
Restriction map B
Genomic Structure
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Length: 1522 aa
Result of homology search against CCDS protein database (
FASTA output,
Multiple alignment)
Entry Exp ID% symbol CCDS46919.1 0 99.9 TOPBP1 CCDS3220.1 2.4e-19 30.3 ECT2 CCDS58860.1 6e-19 31.2 ECT2
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
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Result of InterProScan
Search method interpro_ID From To Entry Definition HMMPfam IPR001357 106 174 PF00533 BRCT IPR001357 195 271 PF00533 BRCT IPR001357 356 431 PF00533 BRCT IPR001357 643 723 PF00533 BRCT IPR001357 902 977 PF00533 BRCT IPR001357 1266 1337 PF00533 BRCT HMMSmart IPR001357 103 179 SM00292 BRCT IPR001357 197 274 SM00292 BRCT IPR001357 356 434 SM00292 BRCT IPR001357 550 623 SM00292 BRCT IPR001357 643 728 SM00292 BRCT IPR001357 902 981 SM00292 BRCT IPR001357 1262 1341 SM00292 BRCT ProfileScan IPR001357 101 172 PS50172 BRCT IPR001357 195 284 PS50172 BRCT IPR001357 354 444 PS50172 BRCT IPR001357 548 633 PS50172 BRCT IPR001357 641 738 PS50172 BRCT IPR001357 900 991 PS50172 BRCT IPR001357 1259 1351 PS50172 BRCT
Result of homology search against disease genes in OMIM database(FASTA output,
Multiple alignment)
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%) NP_008958 1522 607760 99.9 100.0 XP_016861125 1522 607760 99.9 100.0 XP_005247133 1517 607760 99.5 100.0 Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.comCloned ORF Nucleotide sequence for pF1KA0259 Download>KIAA0259 4566 bp ATGTCCAGAAATGACAAAGAACCGTTTTTTGTGAAGTTTTTAAAGTCTTCAGACAATTCC AAATGTTTTTTTAAAGCTCTCGAGTCCATAAAAGAATTCCAATCAGAAGAATATCTTCAG ATTATTACAGAAGAAGAGGCATTGAAGATAAAGGAGAATGATAGATCACTTTATATCTGT GACCCTTTTAGTGGCGTTGTCTTTGATCACCTCAAAAAGCTTGGCTGCAGAATTGTTGGT CCTCAAGTAGTCATATTTTGTATGCACCACCAGCGATGTGTCCCAAGAGCCGAACATCCA GTTTATAATATGGTTATGTCTGATGTAACCATATCTTGTACAAGTCTGGAAAAAGAAAAA AGGGAAGAAGTTCATAAATATGTACAAATGATGGGCGGACGAGTATACAGAGACCTTAAT GTATCAGTAACTCACCTTATTGCAGGAGAAGTTGGTAGCAAAAAATATTTAGTTGCTGCA AACCTGAAGAAACCTATTTTGCTTCCCTCTTGGATAAAAACACTTTGGGAGAAGTCACAA GAGAAAAAAATAACTAGATATACTGATATAAACATGGAAGATTTCAAGTGTCCTATTTTT CTTGGTTGCATAATCTGTGTGACTGGCTTATGTGGCTTAGACAGGAAAGAAGTTCAGCAA CTCACAGTTAAGCATGGAGGTCAATACATGGGACAATTGAAAATGAATGAATGTACACAC CTCATTGTGCAAGAACCAAAAGGTCAGAAGTATGAGTGTGCCAAGAGATGGAATGTACAC TGTGTGACCACACAGTGGTTTTTTGACAGTATTGAGAAAGGTTTTTGTCAGGATGAATCC ATATACAAGACAGAACCTAGACCAGAAGCAAAGACTATGCCCAATTCTTCAACTCCTACC AGCCAGATCAACACAATTGATAGTCGTACTCTTTCAGATGTCAGCAATATTTCCAACATA AATGCAAGTTGCGTAAGTGAATCAATATGTAATTCACTTAACAGCAAACTGGAGCCTACA CTTGAAAATCTAGAAAATCTGGATGTCAGTGCATTTCAAGCACCTGAAGATTTATTAGAT GGTTGTCGGATATATCTTTGCGGTTTTAGTGGCAGAAAGCTAGATAAACTGAGAAGACTT ATTAACAGTGGAGGTGGAGTTCGTTTTAACCAGCTAAATGAAGATGTAACTCATGTTATT GTGGGAGATTATGATGATGAATTGAAGCAGTTTTGGAATAAATCAGCCCACAGGCCTCAT GTAGTGGGAGCAAAGTGGTTGCTAGAGTGTTTCAGTAAAGGTTATATGCTTTCTGAAGAA CCATATATCCATGCTAATTACCAGCCAGTGGAAATTCCAGTTTCACATCAGCCTGAAAGT AAAGCAGCTCTTTTAAAAAAGAAGAACAGCAGCTTCTCTAAGAAAGACTTTGCTCCTAGT GAAAAGCATGAGCAAGCTGATGAAGATCTGCTCTCTCAATATGAAAATGGTAGCTCCACA GTAGTTGAGGCTAAGACGTCTGAAGCCAGGCCCTTTAATGATTCTACTCATGCTGAGCCC TTGAATGATTCTACTCACATTTCTTTGCAAGAAGAAAACCAGTCTTCTGTCAGTCATTGT GTCCCTGATGTTTCTACAATTACTGAAGAAGGCTTATTTAGCCAAAAGAGTTTCCTTGTT TTGGGTTTTAGTAATGAAAATGAATCTAACATCGCAAACATCATAAAAGAAAATGCTGGG AAAATCATGTCCCTTCTGAGCAGAACTGTTGCGGATTATGCTGTGGTTCCTCTGCTGGGG TGTGAAGTGGAAGCCACTGTGGGAGAAGTTGTTACAAATACATGGCTGGTTACTTGCATA GACTATCAGACTTTGTTTGATCCAAAGTCGAATCCTCTCTTCACACCAGTTCCAGTAATG ACAGGAATGACTCCTTTAGAGGATTGTGTTATTTCATTTAGCCAGTGTGCTGGAGCAGAA AAAGAGTCTTTAACATTCCTAGCAAACCTCCTTGGAGCAAGTGTTCAAGAATACTTTGTT CGCAAATCCAATGCAAAGAAAGGCATGTTTGCCAGTACTCATCTTATACTGAAAGAACGT GGTGGCTCTAAATATGAAGCTGCAAAGAAGTGGAATTTACCTGCCGTTACTATAGCTTGG CTGTTGGAGACTGCTAGAACGGGAAAGAGAGCAGACGAAAGCCATTTTCTGATTGAAAAT TCAACTAAAGAAGAACGAAGTTTGGAAACAGAAATAACAAATGGAATCAATCTAAATTCA GATACTGCAGAGCATCCTGGCACACGCCTGCAAACTCACAGAAAAACCGTCGTTACACCT TTAGATATGAACCGCTTTCAGAGTAAAGCTTTCCGTGCTGTGGTCTCACAACATGCCAGA CAGGTCGCAGCCTCCCCAGCAGTAGGACAACCACTTCAGAAGGAGCCCTCGTTACACCTG GATACACCATCAAAATTCCTGTCCAAGGACAAACTCTTCAAGCCTTCCTTTGATGTGAAG GATGCACTTGCAGCCTTGGAAACTCCAGGACGTCCCAGCCAACAGAAAAGGAAACCGAGT ACGCCACTCTCAGAAGTTATTGTCAAAAACTTGCAACTTGCTTTGGCAAATAGCTCTCGA AATGCTGTCGCTCTTTCTGCCAGCCCTCAACTGAAAGAGGCCCAGTCAGAGAAGGAAGAA GCCCCAAAGCCACTTCACAAAGTAGTGGTATGTGTTAGTAAAAAACTCAGTAAGAAGCAG AGTGAACTAAATGGGATCGCAGCCTCTCTAGGAGCAGATTACAGGTGGAGTTTTGATGAA ACAGTGACTCATTTCATCTATCAAGGGCGGCCAAATGACACTAATCGGGAGTATAAATCT GTAAAAGAAAGAGGAGTACACATTGTTTCCGAGCACTGGCTTTTAGATTGTGCCCAAGAG TGTAAACATCTTCCTGAATCTCTTTATCCACATACTTATAATCCCAAAATGAGCTTGGAT ATCAGCGCAGTGCAAGATGGCCGGCTCTGTAATAGTCGACTACTCTCAGCTGTGTCTTCA ACAAAGGATGATGAGCCAGATCCTTTGATTTTAGAAGAAAATGATGTAGACAATATGGCC ACCAATAATAAAGAGTCAGCACCATCAAATGGAAGTGGAAAGAATGACTCTAAAGGAGTT CTGACACAGACCTTAGAGATGAGAGAGAACTTTCAGAAGCAGTTACAGGAGATAATGTCT GCAACATCAATAGTGAAACCCCAAGGGCAGAGGACTTCCCTTTCAAGAAGTGGTTGTAAC AGCGCATCTTCAACCCCTGACAGCACTCGCTCTGCTCGCAGTGGACGAAGTAGAGTCCTA GAGGCACTGAGGCAGTCTCGTCAGACAGTACCTGATGTCAACACAGAGCCTTCCCAAAAT GAACAGATCATTTGGGATGACCCTACAGCAAGGGAGGAGAGAGCAAGGCTTGCCAGCAAT TTGCAGTGGCCTAGTTGTCCCACACAATACTCTGAGCTTCAGGTTGACATTCAAAACTTG GAGGATTCTCCTTTTCAAAAGCCTTTACATGATTCAGAAATTGCTAAACAGGCTGTCTGT GATCCTGGAAACATACGTGTGACTGAAGCTCCCAAACACCCAATCTCTGAAGAACTGGAA ACTCCCATAAAAGACAGCCACCTGATCCCTACGCCTCAAGCCCCCAGTATTGCCTTTCCA CTCGCCAACCCCCCTGTGGCTCCGCACCCTAGAGAAAAGATTATAACGATAGAGGAGACT CATGAAGAATTAAAAAAACAGTACATATTTCAGTTATCATCTCTGAATCCTCAAGAACGT ATTGACTATTGTCATCTGATTGAGAAACTAGGTGGATTGGTGATAGAAAAGCAGTGCTTT GATCCCACCTGTACACACATTGTTGTGGGACATCCACTTCGAAACGAGAAGTATTTAGCC TCAGTGGCAGCTGGGAAGTGGGTGCTTCATCGCTCCTACCTTGAAGCCTGCAGGACTGCT GGACACTTCGTGCAGGAAGAAGACTATGAATGGGGAAGTAGTTCCATACTTGATGTTTTG ACTGGAATCAATGTACAGCAACGAAGACTAGCACTTGCAGCAATGAGATGGAGAAAAAAA ATCCAGCAAAGACAAGAATCTGGCATTGTTGAGGGAGCATTTAGTGGGTGGAAGGTTATT TTACATGTGGATCAGTCTCGAGAAGCAGGCTTCAAACGCCTTCTTCAGTCAGGAGGAGCA AAGGTGCTACCTGGTCATTCTGTACCTTTATTTAAAGAGGCCACACATCTTTTTTCTGAC TTGAATAAACTGAAACCAGATGACTCAGGAGTTAATATAGCAGAAGCTGCTGCCCAGAAC GTGTACTGCTTGAGAACAGAATACATTGCTGATTATCTCATGCAGGAATCACCTCCTCAT GTAGAAAATTACTGTCTACCAGAAGCTATTTCATTTATTCAGAATAATAAGGAACTTGGG ACTGGATTATCACAAAAGAGGAAAGCTCCTACAGAAAAAAATAAAATCAAACGACCTAGA GTACAC
Cloned ORF protein sequence for pF1KA0259 Download>KIAA0259 1522 aa MSRNDKEPFFVKFLKSSDNSKCFFKALESIKEFQSEEYLQIITEEEALKIKENDRSLYIC DPFSGVVFDHLKKLGCRIVGPQVVIFCMHHQRCVPRAEHPVYNMVMSDVTISCTSLEKEK REEVHKYVQMMGGRVYRDLNVSVTHLIAGEVGSKKYLVAANLKKPILLPSWIKTLWEKSQ EKKITRYTDINMEDFKCPIFLGCIICVTGLCGLDRKEVQQLTVKHGGQYMGQLKMNECTH LIVQEPKGQKYECAKRWNVHCVTTQWFFDSIEKGFCQDESIYKTEPRPEAKTMPNSSTPT SQINTIDSRTLSDVSNISNINASCVSESICNSLNSKLEPTLENLENLDVSAFQAPEDLLD GCRIYLCGFSGRKLDKLRRLINSGGGVRFNQLNEDVTHVIVGDYDDELKQFWNKSAHRPH VVGAKWLLECFSKGYMLSEEPYIHANYQPVEIPVSHQPESKAALLKKKNSSFSKKDFAPS EKHEQADEDLLSQYENGSSTVVEAKTSEARPFNDSTHAEPLNDSTHISLQEENQSSVSHC VPDVSTITEEGLFSQKSFLVLGFSNENESNIANIIKENAGKIMSLLSRTVADYAVVPLLG CEVEATVGEVVTNTWLVTCIDYQTLFDPKSNPLFTPVPVMTGMTPLEDCVISFSQCAGAE KESLTFLANLLGASVQEYFVRKSNAKKGMFASTHLILKERGGSKYEAAKKWNLPAVTIAW LLETARTGKRADESHFLIENSTKEERSLETEITNGINLNSDTAEHPGTRLQTHRKTVVTP LDMNRFQSKAFRAVVSQHARQVAASPAVGQPLQKEPSLHLDTPSKFLSKDKLFKPSFDVK DALAALETPGRPSQQKRKPSTPLSEVIVKNLQLALANSSRNAVALSASPQLKEAQSEKEE APKPLHKVVVCVSKKLSKKQSELNGIAASLGADYRWSFDETVTHFIYQGRPNDTNREYKS VKERGVHIVSEHWLLDCAQECKHLPESLYPHTYNPKMSLDISAVQDGRLCNSRLLSAVSS TKDDEPDPLILEENDVDNMATNNKESAPSNGSGKNDSKGVLTQTLEMRENFQKQLQEIMS ATSIVKPQGQRTSLSRSGCNSASSTPDSTRSARSGRSRVLEALRQSRQTVPDVNTEPSQN EQIIWDDPTAREERARLASNLQWPSCPTQYSELQVDIQNLEDSPFQKPLHDSEIAKQAVC DPGNIRVTEAPKHPISEELETPIKDSHLIPTPQAPSIAFPLANPPVAPHPREKIITIEET HEELKKQYIFQLSSLNPQERIDYCHLIEKLGGLVIEKQCFDPTCTHIVVGHPLRNEKYLA SVAAGKWVLHRSYLEACRTAGHFVQEEDYEWGSSSILDVLTGINVQQRRLALAAMRWRKK IQQRQESGIVEGAFSGWKVILHVDQSREAGFKRLLQSGGAKVLPGHSVPLFKEATHLFSD LNKLKPDDSGVNIAEAAAQNVYCLRTEYIADYLMQESPPHVENYCLPEAISFIQNNKELG TGLSQKRKAPTEKNKIKRPRVH
Nucleotide Sequence (with vector) for pF1KA0259 Download>pF1KA0259 7679 bp GGATCTCGATCCCGCGAAATTAATACGACTCACTATAGGGGAATTGTGAGCGGATAACAA TTCCCCACTAGTAATAATTTTCTTTAACTTTAGTAAGGAGCGATCGCCATGTCCAGAAAT GACAAAGAACCGTTTTTTGTGAAGTTTTTAAAGTCTTCAGACAATTCCAAATGTTTTTTT AAAGCTCTCGAGTCCATAAAAGAATTCCAATCAGAAGAATATCTTCAGATTATTACAGAA GAAGAGGCATTGAAGATAAAGGAGAATGATAGATCACTTTATATCTGTGACCCTTTTAGT GGCGTTGTCTTTGATCACCTCAAAAAGCTTGGCTGCAGAATTGTTGGTCCTCAAGTAGTC ATATTTTGTATGCACCACCAGCGATGTGTCCCAAGAGCCGAACATCCAGTTTATAATATG GTTATGTCTGATGTAACCATATCTTGTACAAGTCTGGAAAAAGAAAAAAGGGAAGAAGTT CATAAATATGTACAAATGATGGGCGGACGAGTATACAGAGACCTTAATGTATCAGTAACT CACCTTATTGCAGGAGAAGTTGGTAGCAAAAAATATTTAGTTGCTGCAAACCTGAAGAAA CCTATTTTGCTTCCCTCTTGGATAAAAACACTTTGGGAGAAGTCACAAGAGAAAAAAATA ACTAGATATACTGATATAAACATGGAAGATTTCAAGTGTCCTATTTTTCTTGGTTGCATA ATCTGTGTGACTGGCTTATGTGGCTTAGACAGGAAAGAAGTTCAGCAACTCACAGTTAAG CATGGAGGTCAATACATGGGACAATTGAAAATGAATGAATGTACACACCTCATTGTGCAA GAACCAAAAGGTCAGAAGTATGAGTGTGCCAAGAGATGGAATGTACACTGTGTGACCACA CAGTGGTTTTTTGACAGTATTGAGAAAGGTTTTTGTCAGGATGAATCCATATACAAGACA GAACCTAGACCAGAAGCAAAGACTATGCCCAATTCTTCAACTCCTACCAGCCAGATCAAC ACAATTGATAGTCGTACTCTTTCAGATGTCAGCAATATTTCCAACATAAATGCAAGTTGC GTAAGTGAATCAATATGTAATTCACTTAACAGCAAACTGGAGCCTACACTTGAAAATCTA GAAAATCTGGATGTCAGTGCATTTCAAGCACCTGAAGATTTATTAGATGGTTGTCGGATA TATCTTTGCGGTTTTAGTGGCAGAAAGCTAGATAAACTGAGAAGACTTATTAACAGTGGA GGTGGAGTTCGTTTTAACCAGCTAAATGAAGATGTAACTCATGTTATTGTGGGAGATTAT GATGATGAATTGAAGCAGTTTTGGAATAAATCAGCCCACAGGCCTCATGTAGTGGGAGCA AAGTGGTTGCTAGAGTGTTTCAGTAAAGGTTATATGCTTTCTGAAGAACCATATATCCAT GCTAATTACCAGCCAGTGGAAATTCCAGTTTCACATCAGCCTGAAAGTAAAGCAGCTCTT TTAAAAAAGAAGAACAGCAGCTTCTCTAAGAAAGACTTTGCTCCTAGTGAAAAGCATGAG CAAGCTGATGAAGATCTGCTCTCTCAATATGAAAATGGTAGCTCCACAGTAGTTGAGGCT AAGACGTCTGAAGCCAGGCCCTTTAATGATTCTACTCATGCTGAGCCCTTGAATGATTCT ACTCACATTTCTTTGCAAGAAGAAAACCAGTCTTCTGTCAGTCATTGTGTCCCTGATGTT TCTACAATTACTGAAGAAGGCTTATTTAGCCAAAAGAGTTTCCTTGTTTTGGGTTTTAGT AATGAAAATGAATCTAACATCGCAAACATCATAAAAGAAAATGCTGGGAAAATCATGTCC CTTCTGAGCAGAACTGTTGCGGATTATGCTGTGGTTCCTCTGCTGGGGTGTGAAGTGGAA GCCACTGTGGGAGAAGTTGTTACAAATACATGGCTGGTTACTTGCATAGACTATCAGACT TTGTTTGATCCAAAGTCGAATCCTCTCTTCACACCAGTTCCAGTAATGACAGGAATGACT CCTTTAGAGGATTGTGTTATTTCATTTAGCCAGTGTGCTGGAGCAGAAAAAGAGTCTTTA ACATTCCTAGCAAACCTCCTTGGAGCAAGTGTTCAAGAATACTTTGTTCGCAAATCCAAT GCAAAGAAAGGCATGTTTGCCAGTACTCATCTTATACTGAAAGAACGTGGTGGCTCTAAA TATGAAGCTGCAAAGAAGTGGAATTTACCTGCCGTTACTATAGCTTGGCTGTTGGAGACT GCTAGAACGGGAAAGAGAGCAGACGAAAGCCATTTTCTGATTGAAAATTCAACTAAAGAA GAACGAAGTTTGGAAACAGAAATAACAAATGGAATCAATCTAAATTCAGATACTGCAGAG CATCCTGGCACACGCCTGCAAACTCACAGAAAAACCGTCGTTACACCTTTAGATATGAAC CGCTTTCAGAGTAAAGCTTTCCGTGCTGTGGTCTCACAACATGCCAGACAGGTCGCAGCC TCCCCAGCAGTAGGACAACCACTTCAGAAGGAGCCCTCGTTACACCTGGATACACCATCA AAATTCCTGTCCAAGGACAAACTCTTCAAGCCTTCCTTTGATGTGAAGGATGCACTTGCA GCCTTGGAAACTCCAGGACGTCCCAGCCAACAGAAAAGGAAACCGAGTACGCCACTCTCA GAAGTTATTGTCAAAAACTTGCAACTTGCTTTGGCAAATAGCTCTCGAAATGCTGTCGCT CTTTCTGCCAGCCCTCAACTGAAAGAGGCCCAGTCAGAGAAGGAAGAAGCCCCAAAGCCA CTTCACAAAGTAGTGGTATGTGTTAGTAAAAAACTCAGTAAGAAGCAGAGTGAACTAAAT GGGATCGCAGCCTCTCTAGGAGCAGATTACAGGTGGAGTTTTGATGAAACAGTGACTCAT TTCATCTATCAAGGGCGGCCAAATGACACTAATCGGGAGTATAAATCTGTAAAAGAAAGA GGAGTACACATTGTTTCCGAGCACTGGCTTTTAGATTGTGCCCAAGAGTGTAAACATCTT CCTGAATCTCTTTATCCACATACTTATAATCCCAAAATGAGCTTGGATATCAGCGCAGTG CAAGATGGCCGGCTCTGTAATAGTCGACTACTCTCAGCTGTGTCTTCAACAAAGGATGAT GAGCCAGATCCTTTGATTTTAGAAGAAAATGATGTAGACAATATGGCCACCAATAATAAA GAGTCAGCACCATCAAATGGAAGTGGAAAGAATGACTCTAAAGGAGTTCTGACACAGACC TTAGAGATGAGAGAGAACTTTCAGAAGCAGTTACAGGAGATAATGTCTGCAACATCAATA GTGAAACCCCAAGGGCAGAGGACTTCCCTTTCAAGAAGTGGTTGTAACAGCGCATCTTCA ACCCCTGACAGCACTCGCTCTGCTCGCAGTGGACGAAGTAGAGTCCTAGAGGCACTGAGG CAGTCTCGTCAGACAGTACCTGATGTCAACACAGAGCCTTCCCAAAATGAACAGATCATT TGGGATGACCCTACAGCAAGGGAGGAGAGAGCAAGGCTTGCCAGCAATTTGCAGTGGCCT AGTTGTCCCACACAATACTCTGAGCTTCAGGTTGACATTCAAAACTTGGAGGATTCTCCT TTTCAAAAGCCTTTACATGATTCAGAAATTGCTAAACAGGCTGTCTGTGATCCTGGAAAC ATACGTGTGACTGAAGCTCCCAAACACCCAATCTCTGAAGAACTGGAAACTCCCATAAAA GACAGCCACCTGATCCCTACGCCTCAAGCCCCCAGTATTGCCTTTCCACTCGCCAACCCC CCTGTGGCTCCGCACCCTAGAGAAAAGATTATAACGATAGAGGAGACTCATGAAGAATTA AAAAAACAGTACATATTTCAGTTATCATCTCTGAATCCTCAAGAACGTATTGACTATTGT CATCTGATTGAGAAACTAGGTGGATTGGTGATAGAAAAGCAGTGCTTTGATCCCACCTGT ACACACATTGTTGTGGGACATCCACTTCGAAACGAGAAGTATTTAGCCTCAGTGGCAGCT GGGAAGTGGGTGCTTCATCGCTCCTACCTTGAAGCCTGCAGGACTGCTGGACACTTCGTG CAGGAAGAAGACTATGAATGGGGAAGTAGTTCCATACTTGATGTTTTGACTGGAATCAAT GTACAGCAACGAAGACTAGCACTTGCAGCAATGAGATGGAGAAAAAAAATCCAGCAAAGA CAAGAATCTGGCATTGTTGAGGGAGCATTTAGTGGGTGGAAGGTTATTTTACATGTGGAT CAGTCTCGAGAAGCAGGCTTCAAACGCCTTCTTCAGTCAGGAGGAGCAAAGGTGCTACCT GGTCATTCTGTACCTTTATTTAAAGAGGCCACACATCTTTTTTCTGACTTGAATAAACTG AAACCAGATGACTCAGGAGTTAATATAGCAGAAGCTGCTGCCCAGAACGTGTACTGCTTG AGAACAGAATACATTGCTGATTATCTCATGCAGGAATCACCTCCTCATGTAGAAAATTAC TGTCTACCAGAAGCTATTTCATTTATTCAGAATAATAAGGAACTTGGGACTGGATTATCA CAAAAGAGGAAAGCTCCTACAGAAAAAAATAAAATCAAACGACCTAGAGTACACGTTTAA ACGAATTCGAGCTCGGTACCCGGGGATCCTCTAGAGTCGACCTGCAGGCATGCAAGCTGA TCCGGCTGCTAACAAAGCCCGAAAGGAAGCTGAGTTGGCTGCTGCCACCGCTGAGCAATA ACTAGCATAACCCCTTGGGGCCTCTAAACGGGTCTTGAGGGGTTTTTTGCTGAAAGGAGG AACTATATCCGGTTCGCTTGCTGTCCATAAAACCGCCCAGTCTAGCTATCGCCATGTAAG CCCACTGCAAGCTACCTGCTTTCTCTTTGCGCTTGCGTTTTCCCTTGTCCAGATAGCCCA GTAGCTGACATTCATCCGGGGTCAGCACCGTTTCTGCGGACTGGCTTTCTACGTGTTCCG CTTCCTTTAGCAGCCCTTGCGCCCTGAGTGCTTGCGGCAGCGTGAGCTTCAAAAGAATTG CCAGCTGGGGCGCCCTCTGGTAAGGTTGGGAAGCCCTGCAAAGTAAACTGGATGGCTTTC TTGCCGCCAAGGATCTGATGGCGCAGGGGATCAAGATCTGATCAAGAGACAGGATGACGG TCGTTTCGCATGCTTGAACAAGATGGATTGCACGCAGGTTCTCCGGCCGCTTGGGTGGAG AGGCTATTCGGCTATGACTGGGCACAACAGACAATCGGCTGCTCTGATGCCGCCGTGTTC CGGCTGTCAGCGCAGGGGCGCCCGGTTCTTTTTGTCAAGACCGACCTGTCCGGTGCCCTG AATGAACTGCAGGACGAGGCAGCGCGGCTATCGTGGCTGGCCACGACGGGCGTTCCTTGC GCAGCTGTGCTCGACGTTGTCACTGAAGCGGGAAGGGACTGGCTGCTATTGGGCGAAGTG CCGGGGCAGGATCTCCTGTCATCTCACCTTGCTCCTGCCGAGAAAGTATCCATCATGGCT GATGCAATGCGGCGGCTGCATACGCTTGATCCGGCTACCTGCCCATTCGACCACCAAGCG AAACATCGCATCGAGCGAGCACGCACTCGGATGGAAGCCGGTCTTGTCGATCAGGATGAT CTGGACGAAGAGCATCAGGGGCTCGCGCCAGCCGAACTGTTCGCCAGGCTCAAGGCGCGT ATGCCGGATGGTGAGGATCTCGTCGTGACTCATGGCGATGCCTGCTTGCCGAATATCATG GTGGAAAATGGCCGCTTTTCTGGATTCATCGACTGTGGCCGGCTGGGTGTGGCGGACCGC TATCAGGACATAGCGTTGGCTACCCGTGATATTGCTGAAGAGCTTGGCGGCGAATGGGCT GACCGCTTCCTCGTGCTTTACGGTATCGCCGCTCCCGATTCGCAGCGCATCGCCTTCTAT CGCCTTCTTGACGAGTTCTTCTGAGCGGGACTCTGGGGTTCGAAATGACCGACCAAGCGA CGCCCAACCGGACTATAAAAGGATCTAGGTGAAGATCCTTTTTGATAATCTCATGACCAA AATCCCTTAACGTGAGTTTTCGTTCCACTGAGCGTCAGACCCCGTAGAAAAGATCAAAGG ATCTTCTTGAAATCCTTTTTTTCTGCGCGTAATCTGCTGCTTGCAAACAAAAAAACCACC GCTACCAGCGGTGGTTTGTTTGCCGGATCAAGAGCTACCAACTCTTTTTCCGAAGGTAAC TGGCTTCAGCAGAGCGCAGATACCAAATACTGTCCTTCTAGTGTAGCCGTAGTTAGGCCA CCACTTCAAGAACTCTGTAGCACCGCCTACATACCTCGCTCTGCTAATCCTGTTACCAGT GGCTGCTGCCAGTGGCGATAAGTCGTGTCTTACCGGGTTGGACTCAAGACGATAGTTACC GGATAAGGCGCAGCGGTCGGGCTGAACGGGGGGTTCGTGCACACAGCCCAGCTTGGAGCG AACGACCTACACCGAACTGAGATACCTACAGCGTGAGCTATGAGAAAGCGCCACGCTTCC CGAAGGGAGAAAGGCGGACAGGTATCCGGTAAGCGGCAGGGTCGGAACAGGAGAGCGCAC GAGGGAGCTTCCAGGGGGAAACGCCTGGTATCTTTATAGTCCTGTCGGGTTTCGCCACCT CTGACTTGAGCGTCGATTTTTGTGATGCTCGTCAGGGGGGCGGAGCCTATGGAAAAACGC CAGCAACGCGGCCTTTTTACGGTTCCTGGCCTTTTGCTGGCCTTTTGCTCACATGTTCTT TCCTGCGTTATCCCCTGATTCTGTGGATAACCGTATTACCGCCTTTGAGTGAGCTGATAC CGGAAATACAGGAACGCACGCTGGATGGCCCTTCGCTGGGATGGTGAAACCATGAAAAAT GGCAGCTTCAGTGGATTAAGTGGGGGTAATGTGGCCTGTACCCTCTGGTTGCATAGGTAT TCATACGGTTAAAATTTATCAGGCGCGATTGCGGCAGTTTTTCGGGTGGTTTGTTGCCAT TTTTACCTGTCTGCTGCCGTGATCGCGCTGAACGCGTTTTAGCGGTGCGTACAATTAAGG GATTATGGTAAATCCACTTACTGTCTGCCCTCGTAGCCATCGAGATAAACCGCAGTACTC CGGCCACGATGCGTCCGGCGTAGAGGATCGAGATCTTTTCAGCCTGATACAGATTAAATC AGAACGCAGAAGCGGTCTGATAAAACAGAATTTGCCTGGCGGCAGTAGCGCGGTGGTCCC ACCTGACCCCATGCCGAACTCAGAAGTGAAACGCCGTAGCGCCGATGGTAGTGTGGGGTC TCCCCATGCGAGAGTAGGGAACTGCCAGGCATCAAATAAAACGAAAGGCTCAGTCGAAAG ACTGGGCCTTTCGTTTTATCTGTTGTTTGTCGGTGAACGCTCTCCTGAGTAGGACAAATC CGCCGGGAGCGGATTTGAACGTTGCGAAGCAACGGCCCGGAGGGTGGCGGGCAGGACGCC CGCCATAAACTGCCAGGCATCAAATTAAGCAGAAGGCCATCCTGACGGATGGCCTTTTTG CGTTTCTACAAACTCTTTTGTTTATTTTTCTAAATACATTCAAATATGTATCCGCTCAT
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