Result of FASTA (omim) for pF1KB3277
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3277, 605 aa
  1>>>pF1KB3277 605 - 605 aa - 605 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.9818+/-0.000435; mu= 1.8320+/- 0.027
 mean_var=203.4415+/-42.264, 0's: 0 Z-trim(118.0): 107  B-trim: 1298 in 1/55
 Lambda= 0.089920
 statistics sampled from 30404 (30513) to 30404 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.696), E-opt: 0.2 (0.358), width:  16
 Scan time: 10.600

The best scores are:                                      opt bits E(85289)
NP_000715 (OMIM: 600003,611876) voltage-dependent  ( 605) 4013 533.7 6.9e-151
NP_963865 (OMIM: 600003,611876) voltage-dependent  ( 632) 3897 518.7 2.4e-146
NP_963890 (OMIM: 600003,611876) voltage-dependent  ( 660) 3897 518.7 2.5e-146
XP_006717565 (OMIM: 600003,611876) PREDICTED: volt ( 600) 3894 518.2  3e-146
NP_963884 (OMIM: 600003,611876) voltage-dependent  ( 606) 3894 518.3 3.1e-146
NP_963864 (OMIM: 600003,611876) voltage-dependent  ( 612) 3894 518.3 3.1e-146
NP_001316989 (OMIM: 600003,611876) voltage-depende ( 567) 2619 352.8 1.8e-96
XP_005252645 (OMIM: 600003,611876) PREDICTED: volt ( 574) 2619 352.8 1.8e-96
NP_001161417 (OMIM: 600003,611876) voltage-depende ( 594) 2619 352.8 1.9e-96
NP_963887 (OMIM: 600003,611876) voltage-dependent  ( 622) 2619 352.9 1.9e-96
XP_011517961 (OMIM: 600003,611876) PREDICTED: volt ( 582) 2617 352.6 2.2e-96
NP_963866 (OMIM: 600003,611876) voltage-dependent  ( 608) 2617 352.6 2.3e-96
NP_963891 (OMIM: 600003,611876) voltage-dependent  ( 636) 2617 352.6 2.4e-96
XP_016872114 (OMIM: 600003,611876) PREDICTED: volt ( 380) 2506 338.1 3.4e-92
XP_005252648 (OMIM: 600003,611876) PREDICTED: volt ( 380) 2506 338.1 3.4e-92
XP_005257702 (OMIM: 114207) PREDICTED: voltage-dep ( 643) 2337 316.3   2e-85
XP_006722135 (OMIM: 114207) PREDICTED: voltage-dep ( 596) 2336 316.1 2.1e-85
XP_016880513 (OMIM: 114207) PREDICTED: voltage-dep ( 599) 2334 315.9 2.5e-85
NP_954855 (OMIM: 114207) voltage-dependent L-type  ( 523) 2201 298.6 3.5e-80
XP_005257703 (OMIM: 114207) PREDICTED: voltage-dep ( 400) 1690 232.2 2.6e-60
XP_016880515 (OMIM: 114207) PREDICTED: voltage-dep ( 431) 1576 217.5 7.7e-56
XP_016880514 (OMIM: 114207) PREDICTED: voltage-dep ( 551) 1473 204.2 9.9e-52
NP_000714 (OMIM: 114207) voltage-dependent L-type  ( 598) 1473 204.2 1.1e-51
XP_016880516 (OMIM: 114207) PREDICTED: voltage-dep ( 370) 1379 191.9 3.4e-48
XP_016880518 (OMIM: 114207) PREDICTED: voltage-dep ( 370) 1379 191.9 3.4e-48
XP_016880517 (OMIM: 114207) PREDICTED: voltage-dep ( 370) 1379 191.9 3.4e-48
NP_954856 (OMIM: 114207) voltage-dependent L-type  ( 478) 1337 186.5 1.8e-46
NP_001317046 (OMIM: 601949,607682,613855) voltage- ( 334) 1320 184.2 6.2e-46
XP_011510098 (OMIM: 601949,607682,613855) PREDICTE ( 472) 1320 184.3 8.3e-46
NP_001317047 (OMIM: 601949,607682,613855) voltage- ( 473) 1320 184.3 8.3e-46
NP_001307651 (OMIM: 601949,607682,613855) voltage- ( 473) 1320 184.3 8.3e-46
NP_001005747 (OMIM: 601949,607682,613855) voltage- ( 486) 1320 184.3 8.5e-46
NP_001005746 (OMIM: 601949,607682,613855) voltage- ( 502) 1320 184.3 8.7e-46
NP_000717 (OMIM: 601949,607682,613855) voltage-dep ( 520) 1320 184.3 8.9e-46
XP_016860374 (OMIM: 601949,607682,613855) PREDICTE ( 302) 1233 172.9 1.4e-42
NP_001317043 (OMIM: 601949,607682,613855) voltage- ( 302) 1233 172.9 1.4e-42
NP_001193844 (OMIM: 601958) voltage-dependent L-ty ( 443) 1194 167.9 6.5e-41
NP_001193846 (OMIM: 601958) voltage-dependent L-ty ( 471) 1194 167.9 6.9e-41
NP_001193845 (OMIM: 601958) voltage-dependent L-ty ( 483) 1194 167.9   7e-41
NP_000716 (OMIM: 601958) voltage-dependent L-type  ( 484) 1194 167.9   7e-41
XP_016875447 (OMIM: 601958) PREDICTED: voltage-dep ( 308) 1100 155.6 2.3e-37
XP_016875446 (OMIM: 601958) PREDICTED: voltage-dep ( 308) 1100 155.6 2.3e-37
XP_011537030 (OMIM: 601958) PREDICTED: voltage-dep ( 308) 1100 155.6 2.3e-37
XP_016875448 (OMIM: 601958) PREDICTED: voltage-dep ( 308) 1100 155.6 2.3e-37
XP_011537029 (OMIM: 601958) PREDICTED: voltage-dep ( 308) 1100 155.6 2.3e-37
NP_001139270 (OMIM: 601949,607682,613855) voltage- ( 458) 1008 143.8 1.2e-33
XP_016880519 (OMIM: 114207) PREDICTED: voltage-dep ( 355)  826 120.1 1.3e-26
XP_016860375 (OMIM: 601949,607682,613855) PREDICTE ( 281)  807 117.6 5.9e-26
NP_001317045 (OMIM: 601949,607682,613855) voltage- ( 410)  801 116.9 1.4e-25
NP_001317044 (OMIM: 601949,607682,613855) voltage- ( 423)  801 116.9 1.4e-25


>>NP_000715 (OMIM: 600003,611876) voltage-dependent L-ty  (605 aa)
 initn: 4013 init1: 4013 opt: 4013  Z-score: 2829.9  bits: 533.7 E(85289): 6.9e-151
Smith-Waterman score: 4013; 100.0% identity (100.0% similar) in 605 aa overlap (1-605:1-605)

               10        20        30        40        50        60
pF1KB3 MQCCGLVHRRRVRVSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MQCCGLVHRRRVRVSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 AFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 PVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 ENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 VTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 SEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQ
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 AKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 LSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 APHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 APHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETH
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 GSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRD
              550       560       570       580       590       600

            
pF1KB3 VYIRQ
       :::::
NP_000 VYIRQ
            

>>NP_963865 (OMIM: 600003,611876) voltage-dependent L-ty  (632 aa)
 initn: 3897 init1: 3897 opt: 3897  Z-score: 2748.3  bits: 518.7 E(85289): 2.4e-146
Smith-Waterman score: 3897; 99.7% identity (99.7% similar) in 592 aa overlap (14-605:41-632)

                                10        20        30        40   
pF1KB3                  MQCCGLVHRRRVRVSYGSADSYTSRPSDSDVSLEEDREAVRRE
                                     :  :::::::::::::::::::::::::::
NP_963 KISYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRRE
               20        30        40        50        60        70

            50        60        70        80        90       100   
pF1KB3 AERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 AERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDW
               80        90       100       110       120       130

           110       120       130       140       150       160   
pF1KB3 WIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 WIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKS
              140       150       160       170       180       190

           170       180       190       200       210       220   
pF1KB3 TPPSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 TPPSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVV
              200       210       220       230       240       250

           230       240       250       260       270       280   
pF1KB3 PSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 PSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSK
              260       270       280       290       300       310

           290       300       310       320       330       340   
pF1KB3 HAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 HAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKI
              320       330       340       350       360       370

           350       360       370       380       390       400   
pF1KB3 SSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 SSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLE
              380       390       400       410       420       430

           410       420       430       440       450       460   
pF1KB3 AYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 AYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEE
              440       450       460       470       480       490

           470       480       490       500       510       520   
pF1KB3 EPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 EPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDH
              500       510       520       530       540       550

           530       540       550       560       570       580   
pF1KB3 VDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 VDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKD
              560       570       580       590       600       610

           590       600     
pF1KB3 GEVISKKRNEAGEWNRDVYIRQ
       ::::::::::::::::::::::
NP_963 GEVISKKRNEAGEWNRDVYIRQ
              620       630  

>>NP_963890 (OMIM: 600003,611876) voltage-dependent L-ty  (660 aa)
 initn: 3897 init1: 3897 opt: 3897  Z-score: 2748.0  bits: 518.7 E(85289): 2.5e-146
Smith-Waterman score: 3897; 99.7% identity (99.7% similar) in 592 aa overlap (14-605:69-660)

                                10        20        30        40   
pF1KB3                  MQCCGLVHRRRVRVSYGSADSYTSRPSDSDVSLEEDREAVRRE
                                     :  :::::::::::::::::::::::::::
NP_963 AQSYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRRE
       40        50        60        70        80        90        

            50        60        70        80        90       100   
pF1KB3 AERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 AERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDW
      100       110       120       130       140       150        

           110       120       130       140       150       160   
pF1KB3 WIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 WIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKS
      160       170       180       190       200       210        

           170       180       190       200       210       220   
pF1KB3 TPPSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 TPPSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVV
      220       230       240       250       260       270        

           230       240       250       260       270       280   
pF1KB3 PSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 PSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSK
      280       290       300       310       320       330        

           290       300       310       320       330       340   
pF1KB3 HAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 HAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKI
      340       350       360       370       380       390        

           350       360       370       380       390       400   
pF1KB3 SSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 SSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLE
      400       410       420       430       440       450        

           410       420       430       440       450       460   
pF1KB3 AYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 AYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEE
      460       470       480       490       500       510        

           470       480       490       500       510       520   
pF1KB3 EPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 EPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDH
      520       530       540       550       560       570        

           530       540       550       560       570       580   
pF1KB3 VDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 VDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKD
      580       590       600       610       620       630        

           590       600     
pF1KB3 GEVISKKRNEAGEWNRDVYIRQ
       ::::::::::::::::::::::
NP_963 GEVISKKRNEAGEWNRDVYIRQ
      640       650       660

>>XP_006717565 (OMIM: 600003,611876) PREDICTED: voltage-  (600 aa)
 initn: 3894 init1: 3894 opt: 3894  Z-score: 2746.5  bits: 518.2 E(85289): 3e-146
Smith-Waterman score: 3894; 100.0% identity (100.0% similar) in 589 aa overlap (17-605:12-600)

               10        20        30        40        50        60
pF1KB3 MQCCGLVHRRRVRVSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPV
                       ::::::::::::::::::::::::::::::::::::::::::::
XP_006      MYYDDDEPSEVGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPV
                    10        20        30        40        50     

               70        80        90       100       110       120
pF1KB3 AFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPS
          60        70        80        90       100       110     

              130       140       150       160       170       180
pF1KB3 PVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAE
         120       130       140       150       160       170     

              190       200       210       220       230       240
pF1KB3 ENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYE
         180       190       200       210       220       230     

              250       260       270       280       290       300
pF1KB3 VTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQ
         240       250       260       270       280       290     

              310       320       330       340       350       360
pF1KB3 SEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQ
         300       310       320       330       340       350     

              370       380       390       400       410       420
pF1KB3 AKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPL
         360       370       380       390       400       410     

              430       440       450       460       470       480
pF1KB3 LSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSS
         420       430       440       450       460       470     

              490       500       510       520       530       540
pF1KB3 APHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 APHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETH
         480       490       500       510       520       530     

              550       560       570       580       590       600
pF1KB3 GSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRD
         540       550       560       570       580       590     

            
pF1KB3 VYIRQ
       :::::
XP_006 VYIRQ
         600

>>NP_963884 (OMIM: 600003,611876) voltage-dependent L-ty  (606 aa)
 initn: 3894 init1: 3894 opt: 3894  Z-score: 2746.5  bits: 518.3 E(85289): 3.1e-146
Smith-Waterman score: 3894; 100.0% identity (100.0% similar) in 589 aa overlap (17-605:18-606)

                10        20        30        40        50         
pF1KB3  MQCCGLVHRRRVRVSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKP
                        :::::::::::::::::::::::::::::::::::::::::::
NP_963 MLDRRLIAPQTKYIIPGGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKP
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB3 VAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 VAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIP
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB3 SPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 SPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDA
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KB3 EENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 EENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGY
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KB3 EVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 EVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEV
              250       260       270       280       290       300

     300       310       320       330       340       350         
pF1KB3 QSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 QSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKS
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KB3 QAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 QAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNP
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KB3 LLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 LLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSS
              430       440       450       460       470       480

     480       490       500       510       520       530         
pF1KB3 SAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 SAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDET
              490       500       510       520       530       540

     540       550       560       570       580       590         
pF1KB3 HGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 HGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNR
              550       560       570       580       590       600

     600     
pF1KB3 DVYIRQ
       ::::::
NP_963 DVYIRQ
             

>>NP_963864 (OMIM: 600003,611876) voltage-dependent L-ty  (612 aa)
 initn: 3894 init1: 3894 opt: 3894  Z-score: 2746.4  bits: 518.3 E(85289): 3.1e-146
Smith-Waterman score: 3894; 100.0% identity (100.0% similar) in 589 aa overlap (17-605:24-612)

                      10        20        30        40        50   
pF1KB3        MQCCGLVHRRRVRVSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLE
                              :::::::::::::::::::::::::::::::::::::
NP_963 MKATWIRLLKRAKGGRLKNSDICGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLE
               10        20        30        40        50        60

            60        70        80        90       100       110   
pF1KB3 KAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 KAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGC
               70        80        90       100       110       120

           120       130       140       150       160       170   
pF1KB3 EIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 EIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDID
              130       140       150       160       170       180

           180       190       200       210       220       230   
pF1KB3 ATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 ATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVG
              190       200       210       220       230       240

           240       250       260       270       280       290   
pF1KB3 PSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 PSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTR
              250       260       270       280       290       300

           300       310       320       330       340       350   
pF1KB3 SSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 SSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLI
              310       320       330       340       350       360

           360       370       380       390       400       410   
pF1KB3 KSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 KSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPS
              370       380       390       400       410       420

           420       430       440       450       460       470   
pF1KB3 SSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 SSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKS
              430       440       450       460       470       480

           480       490       500       510       520       530   
pF1KB3 QHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 QHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDH
              490       500       510       520       530       540

           540       550       560       570       580       590   
pF1KB3 NHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 NHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNE
              550       560       570       580       590       600

           600     
pF1KB3 AGEWNRDVYIRQ
       ::::::::::::
NP_963 AGEWNRDVYIRQ
              610  

>>NP_001316989 (OMIM: 600003,611876) voltage-dependent L  (567 aa)
 initn: 3709 init1: 2599 opt: 2619  Z-score: 1853.0  bits: 352.8 E(85289): 1.8e-96
Smith-Waterman score: 3642; 93.2% identity (93.7% similar) in 605 aa overlap (1-605:1-567)

               10        20        30        40        50        60
pF1KB3 MQCCGLVHRRRVRVSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQCCGLVHRRRVRVSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 AFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 PVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAE
       :::::::::::::::::::::::::::::::::::::::::::::::::           
NP_001 PVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSA-----------
              130       140       150       160                    

              190       200       210       220       230       240
pF1KB3 ENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYE
                              :.:.    :.:::::::::::::::::::::::::::
NP_001 -----------------------KQKQ----KSTEHTPPYDVVPSMRPVVLVGPSLKGYE
                            170           180       190       200  

              250       260       270       280       290       300
pF1KB3 VTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQ
            210       220       230       240       250       260  

              310       320       330       340       350       360
pF1KB3 SEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQ
            270       280       290       300       310       320  

              370       380       390       400       410       420
pF1KB3 AKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPL
            330       340       350       360       370       380  

              430       440       450       460       470       480
pF1KB3 LSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSS
            390       400       410       420       430       440  

              490       500       510       520       530       540
pF1KB3 APHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETH
            450       460       470       480       490       500  

              550       560       570       580       590       600
pF1KB3 GSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRD
            510       520       530       540       550       560  

            
pF1KB3 VYIRQ
       :::::
NP_001 VYIRQ
            

>>XP_005252645 (OMIM: 600003,611876) PREDICTED: voltage-  (574 aa)
 initn: 3590 init1: 2599 opt: 2619  Z-score: 1852.9  bits: 352.8 E(85289): 1.8e-96
Smith-Waterman score: 3523; 93.0% identity (93.5% similar) in 589 aa overlap (17-605:24-574)

                      10        20        30        40        50   
pF1KB3        MQCCGLVHRRRVRVSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLE
                              :::::::::::::::::::::::::::::::::::::
XP_005 MKATWIRLLKRAKGGRLKNSDICGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLE
               10        20        30        40        50        60

            60        70        80        90       100       110   
pF1KB3 KAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGC
               70        80        90       100       110       120

           120       130       140       150       160       170   
pF1KB3 EIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::    
XP_005 EIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSA----
              130       140       150       160       170          

           180       190       200       210       220       230   
pF1KB3 ATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVG
                                     :.:.    :.::::::::::::::::::::
XP_005 ------------------------------KQKQ----KSTEHTPPYDVVPSMRPVVLVG
                                      180           190       200  

           240       250       260       270       280       290   
pF1KB3 PSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTR
            210       220       230       240       250       260  

           300       310       320       330       340       350   
pF1KB3 SSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLI
            270       280       290       300       310       320  

           360       370       380       390       400       410   
pF1KB3 KSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPS
            330       340       350       360       370       380  

           420       430       440       450       460       470   
pF1KB3 SSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKS
            390       400       410       420       430       440  

           480       490       500       510       520       530   
pF1KB3 QHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDH
            450       460       470       480       490       500  

           540       550       560       570       580       590   
pF1KB3 NHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNE
            510       520       530       540       550       560  

           600     
pF1KB3 AGEWNRDVYIRQ
       ::::::::::::
XP_005 AGEWNRDVYIRQ
            570    

>>NP_001161417 (OMIM: 600003,611876) voltage-dependent L  (594 aa)
 initn: 3593 init1: 2599 opt: 2619  Z-score: 1852.7  bits: 352.8 E(85289): 1.9e-96
Smith-Waterman score: 3526; 92.7% identity (93.2% similar) in 592 aa overlap (14-605:41-594)

                                10        20        30        40   
pF1KB3                  MQCCGLVHRRRVRVSYGSADSYTSRPSDSDVSLEEDREAVRRE
                                     :  :::::::::::::::::::::::::::
NP_001 KISYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRRE
               20        30        40        50        60        70

            50        60        70        80        90       100   
pF1KB3 AERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDW
               80        90       100       110       120       130

           110       120       130       140       150       160   
pF1KB3 WIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKS
              140       150       160       170       180       190

           170       180       190       200       210       220   
pF1KB3 TPPSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVV
       ::::::                                  :.:.    :.::::::::::
NP_001 TPPSSA----------------------------------KQKQ----KSTEHTPPYDVV
                                                200           210  

           230       240       250       260       270       280   
pF1KB3 PSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSK
            220       230       240       250       260       270  

           290       300       310       320       330       340   
pF1KB3 HAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKI
            280       290       300       310       320       330  

           350       360       370       380       390       400   
pF1KB3 SSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLE
            340       350       360       370       380       390  

           410       420       430       440       450       460   
pF1KB3 AYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEE
            400       410       420       430       440       450  

           470       480       490       500       510       520   
pF1KB3 EPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDH
            460       470       480       490       500       510  

           530       540       550       560       570       580   
pF1KB3 VDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKD
            520       530       540       550       560       570  

           590       600     
pF1KB3 GEVISKKRNEAGEWNRDVYIRQ
       ::::::::::::::::::::::
NP_001 GEVISKKRNEAGEWNRDVYIRQ
            580       590    

>>NP_963887 (OMIM: 600003,611876) voltage-dependent L-ty  (622 aa)
 initn: 3593 init1: 2599 opt: 2619  Z-score: 1852.4  bits: 352.9 E(85289): 1.9e-96
Smith-Waterman score: 3526; 92.7% identity (93.2% similar) in 592 aa overlap (14-605:69-622)

                                10        20        30        40   
pF1KB3                  MQCCGLVHRRRVRVSYGSADSYTSRPSDSDVSLEEDREAVRRE
                                     :  :::::::::::::::::::::::::::
NP_963 AQSYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRRE
       40        50        60        70        80        90        

            50        60        70        80        90       100   
pF1KB3 AERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 AERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDW
      100       110       120       130       140       150        

           110       120       130       140       150       160   
pF1KB3 WIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 WIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKS
      160       170       180       190       200       210        

           170       180       190       200       210       220   
pF1KB3 TPPSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVV
       ::::::                                  :.:.    :.::::::::::
NP_963 TPPSSA----------------------------------KQKQ----KSTEHTPPYDVV
      220                                             230       240

           230       240       250       260       270       280   
pF1KB3 PSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 PSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSK
              250       260       270       280       290       300

           290       300       310       320       330       340   
pF1KB3 HAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 HAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKI
              310       320       330       340       350       360

           350       360       370       380       390       400   
pF1KB3 SSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 SSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLE
              370       380       390       400       410       420

           410       420       430       440       450       460   
pF1KB3 AYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 AYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEE
              430       440       450       460       470       480

           470       480       490       500       510       520   
pF1KB3 EPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 EPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDH
              490       500       510       520       530       540

           530       540       550       560       570       580   
pF1KB3 VDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 VDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKD
              550       560       570       580       590       600

           590       600     
pF1KB3 GEVISKKRNEAGEWNRDVYIRQ
       ::::::::::::::::::::::
NP_963 GEVISKKRNEAGEWNRDVYIRQ
              610       620  




605 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Nov  8 17:10:42 2016 done: Tue Nov  8 17:10:44 2016
 Total Scan time: 10.600 Total Display time:  0.140

Function used was FASTA [36.3.4 Apr, 2011]
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