Result of FASTA (omim) for
pF1KE9257
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9257, 859 aa
1>>>pF1KE9257 859 - 859 aa - 859 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.2921+/-0.000378; mu= 12.2481+/- 0.024
mean_var=117.1601+/-23.602, 0's: 0 Z-trim(116.6): 46 B-trim: 0 in 0/51
Lambda= 0.118491
statistics sampled from 27942 (27988) to 27942 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.664), E-opt: 0.2 (0.328), width: 16
Scan time: 11.010
The best scores are: opt bits E(85289)
NP_036286 (OMIM: 606229) protein argonaute-2 isofo ( 859) 5866 1014.2 0
XP_011515267 (OMIM: 606229) PREDICTED: protein arg ( 873) 5815 1005.5 0
XP_011515270 (OMIM: 606229) PREDICTED: protein arg ( 918) 5810 1004.6 0
XP_011515268 (OMIM: 606229) PREDICTED: protein arg ( 813) 5530 956.7 0
XP_016868806 (OMIM: 606229) PREDICTED: protein arg ( 782) 5310 919.1 0
NP_001158095 (OMIM: 606229) protein argonaute-2 is ( 825) 4936 855.2 0
NP_036331 (OMIM: 606228) protein argonaute-1 isofo ( 857) 4926 853.5 0
NP_001304051 (OMIM: 606228) protein argonaute-1 is ( 891) 4926 853.5 0
XP_011539538 (OMIM: 606228) PREDICTED: protein arg ( 860) 4910 850.8 0
NP_001304052 (OMIM: 606228) protein argonaute-1 is ( 782) 4607 798.9 0
NP_079128 (OMIM: 607355) protein argonaute-3 isofo ( 860) 4302 746.8 9.6e-215
XP_005270632 (OMIM: 607355) PREDICTED: protein arg ( 860) 4302 746.8 9.6e-215
XP_016856012 (OMIM: 607355) PREDICTED: protein arg ( 860) 4302 746.8 9.6e-215
XP_016856506 (OMIM: 606228) PREDICTED: protein arg ( 873) 4293 745.3 2.8e-214
XP_011539181 (OMIM: 607355) PREDICTED: protein arg ( 845) 4284 743.7 8e-214
XP_016856505 (OMIM: 606228) PREDICTED: protein arg ( 876) 4277 742.6 1.9e-213
XP_016856508 (OMIM: 606228) PREDICTED: protein arg ( 706) 4152 721.1 4.2e-207
XP_016856016 (OMIM: 607355) PREDICTED: protein arg ( 626) 3722 647.6 5.1e-185
XP_016856015 (OMIM: 607355) PREDICTED: protein arg ( 626) 3722 647.6 5.1e-185
XP_016856014 (OMIM: 607355) PREDICTED: protein arg ( 626) 3722 647.6 5.1e-185
NP_803171 (OMIM: 607355) protein argonaute-3 isofo ( 626) 3722 647.6 5.1e-185
XP_011539184 (OMIM: 607355) PREDICTED: protein arg ( 626) 3722 647.6 5.1e-185
XP_016856013 (OMIM: 607355) PREDICTED: protein arg ( 626) 3722 647.6 5.1e-185
XP_016856017 (OMIM: 607355) PREDICTED: protein arg ( 585) 3504 610.3 8e-174
XP_005270633 (OMIM: 607355) PREDICTED: protein arg ( 585) 3504 610.3 8e-174
XP_016856507 (OMIM: 606228) PREDICTED: protein arg ( 725) 3503 610.2 1.1e-173
NP_060099 (OMIM: 607356) protein argonaute-4 [Homo ( 861) 3450 601.2 6.7e-171
XP_005270636 (OMIM: 607356) PREDICTED: protein arg ( 794) 3178 554.7 6.2e-157
XP_005270635 (OMIM: 607356) PREDICTED: protein arg ( 794) 3178 554.7 6.2e-157
XP_011539185 (OMIM: 607356) PREDICTED: protein arg ( 711) 2711 474.8 6.1e-133
XP_011539186 (OMIM: 607356) PREDICTED: protein arg ( 660) 2432 427.1 1.3e-118
XP_016856018 (OMIM: 607356) PREDICTED: protein arg ( 378) 2004 353.8 8.5e-97
NP_001177900 (OMIM: 605571) piwi-like protein 1 is ( 829) 455 89.2 8.6e-17
XP_016875718 (OMIM: 605571) PREDICTED: piwi-like p ( 832) 455 89.2 8.6e-17
XP_011537308 (OMIM: 605571) PREDICTED: piwi-like p ( 481) 444 87.2 2e-16
NP_004755 (OMIM: 605571) piwi-like protein 1 isofo ( 861) 444 87.3 3.3e-16
XP_011537304 (OMIM: 605571) PREDICTED: piwi-like p ( 861) 444 87.3 3.3e-16
XP_011537305 (OMIM: 605571) PREDICTED: piwi-like p ( 861) 444 87.3 3.3e-16
XP_011537306 (OMIM: 605571) PREDICTED: piwi-like p ( 861) 444 87.3 3.3e-16
NP_001008496 (OMIM: 610314) piwi-like protein 3 is ( 882) 432 85.3 1.4e-15
NP_060538 (OMIM: 610312) piwi-like protein 2 isofo ( 973) 412 81.9 1.6e-14
NP_001129193 (OMIM: 610312) piwi-like protein 2 is ( 973) 412 81.9 1.6e-14
NP_001242904 (OMIM: 610314) piwi-like protein 3 is ( 873) 405 80.7 3.4e-14
NP_689644 (OMIM: 610315) piwi-like protein 4 [Homo ( 852) 379 76.2 7.2e-13
NP_001317409 (OMIM: 610312) piwi-like protein 2 is ( 937) 337 69.0 1.1e-10
XP_011537307 (OMIM: 605571) PREDICTED: piwi-like p ( 819) 203 46.1 0.00079
>>NP_036286 (OMIM: 606229) protein argonaute-2 isoform 1 (859 aa)
initn: 5866 init1: 5866 opt: 5866 Z-score: 5421.3 bits: 1014.2 E(85289): 0
Smith-Waterman score: 5866; 100.0% identity (100.0% similar) in 859 aa overlap (1-859:1-859)
10 20 30 40 50 60
pF1KE9 MYSGAGPALAPPAPPPPIQGYAFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MYSGAGPALAPPAPPPPIQGYAFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 IKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 IKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 GEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 FFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 FFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 KSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQES
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 GQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 TSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 TSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 GGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 AGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 AGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 GMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 PPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE9 PTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE9 NERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 NERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE9 ILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQ
790 800 810 820 830 840
850
pF1KE9 ALAKAVQVHQDTLRTMYFA
:::::::::::::::::::
NP_036 ALAKAVQVHQDTLRTMYFA
850
>>XP_011515267 (OMIM: 606229) PREDICTED: protein argonau (873 aa)
initn: 5815 init1: 5815 opt: 5815 Z-score: 5374.0 bits: 1005.5 E(85289): 0
Smith-Waterman score: 5815; 100.0% identity (100.0% similar) in 852 aa overlap (8-859:22-873)
10 20 30 40
pF1KE9 MYSGAGPALAPPAPPPPIQGYAFKPPPRPDFGTSGRTIKLQANFFE
:::::::::::::::::::::::::::::::::::::::
XP_011 MPLCSSVRLRWENGLTADLALALAPPAPPPPIQGYAFKPPPRPDFGTSGRTIKLQANFFE
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE9 MDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE9 PIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVM
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE9 RHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYK
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE9 AQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTR
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE9 RPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNI
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE9 VAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMT
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE9 DVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVH
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE9 LKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKT
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE9 PVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPV
550 560 570 580 590 600
590 600 610 620 630 640
pF1KE9 FQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMV
610 620 630 640 650 660
650 660 670 680 690 700
pF1KE9 RELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIV
670 680 690 700 710 720
710 720 730 740 750 760
pF1KE9 VQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYH
730 740 750 760 770 780
770 780 790 800 810 820
pF1KE9 VLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAE
790 800 810 820 830 840
830 840 850
pF1KE9 GSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA
:::::::::::::::::::::::::::::::::
XP_011 GSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA
850 860 870
>>XP_011515270 (OMIM: 606229) PREDICTED: protein argonau (918 aa)
initn: 5810 init1: 5810 opt: 5810 Z-score: 5369.1 bits: 1004.6 E(85289): 0
Smith-Waterman score: 5810; 100.0% identity (100.0% similar) in 851 aa overlap (9-859:68-918)
10 20 30
pF1KE9 MYSGAGPALAPPAPPPPIQGYAFKPPPRPDFGTSGRTI
::::::::::::::::::::::::::::::
XP_011 TFLRLVLAEHKHKARCQCRAAPCLPSVPIPLAPPAPPPPIQGYAFKPPPRPDFGTSGRTI
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE9 KLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRK
100 110 120 130 140 150
100 110 120 130 140 150
pF1KE9 NLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFET
160 170 180 190 200 210
160 170 180 190 200 210
pF1KE9 IQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNID
220 230 240 250 260 270
220 230 240 250 260 270
pF1KE9 VSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRK
280 290 300 310 320 330
280 290 300 310 320 330
pF1KE9 YRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTY
340 350 360 370 380 390
340 350 360 370 380 390
pF1KE9 LPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFG
400 410 420 430 440 450
400 410 420 430 440 450
pF1KE9 IMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAP
460 470 480 490 500 510
460 470 480 490 500 510
pF1KE9 QRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLV
520 530 540 550 560 570
520 530 540 550 560 570
pF1KE9 VVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNIL
580 590 600 610 620 630
580 590 600 610 620 630
pF1KE9 LPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEI
640 650 660 670 680 690
640 650 660 670 680 690
pF1KE9 IQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDY
700 710 720 730 740 750
700 710 720 730 740 750
pF1KE9 QPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQG
760 770 780 790 800 810
760 770 780 790 800 810
pF1KE9 TSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLV
820 830 840 850 860 870
820 830 840 850
pF1KE9 DKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA
:::::::::::::::::::::::::::::::::::::::::
XP_011 DKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA
880 890 900 910
>>XP_011515268 (OMIM: 606229) PREDICTED: protein argonau (813 aa)
initn: 5530 init1: 5530 opt: 5530 Z-score: 5111.2 bits: 956.7 E(85289): 0
Smith-Waterman score: 5530; 100.0% identity (100.0% similar) in 813 aa overlap (47-859:1-813)
20 30 40 50 60 70
pF1KE9 PIQGYAFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVE
::::::::::::::::::::::::::::::
XP_011 MDIPKIDIYHYELDIKPEKCPRRVNREIVE
10 20 30
80 90 100 110 120 130
pF1KE9 HMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVS
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE9 CVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGR
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE9 EVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRV
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE9 KFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRH
220 230 240 250 260 270
320 330 340 350 360 370
pF1KE9 KLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQ
280 290 300 310 320 330
380 390 400 410 420 430
pF1KE9 EEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWD
340 350 360 370 380 390
440 450 460 470 480 490
pF1KE9 MRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQ
400 410 420 430 440 450
500 510 520 530 540 550
pF1KE9 GADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTT
460 470 480 490 500 510
560 570 580 590 600 610
pF1KE9 PQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVG
520 530 540 550 560 570
620 630 640 650 660 670
pF1KE9 SMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQF
580 590 600 610 620 630
680 690 700 710 720 730
pF1KE9 QQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTV
640 650 660 670 680 690
740 750 760 770 780 790
pF1KE9 DTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRS
700 710 720 730 740 750
800 810 820 830 840 850
pF1KE9 VSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTM
760 770 780 790 800 810
pF1KE9 YFA
:::
XP_011 YFA
>>XP_016868806 (OMIM: 606229) PREDICTED: protein argonau (782 aa)
initn: 5310 init1: 5310 opt: 5310 Z-score: 4908.2 bits: 919.1 E(85289): 0
Smith-Waterman score: 5310; 100.0% identity (100.0% similar) in 782 aa overlap (78-859:1-782)
50 60 70 80 90 100
pF1KE9 DIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLP
::::::::::::::::::::::::::::::
XP_016 MVQHFKTQIFGDRKPVFDGRKNLYTAMPLP
10 20 30
110 120 130 140 150 160
pF1KE9 IGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMR
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE9 HLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKA
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE9 QPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRR
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE9 PASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIV
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE9 AGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTD
280 290 300 310 320 330
410 420 430 440 450 460
pF1KE9 VTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHL
340 350 360 370 380 390
470 480 490 500 510 520
pF1KE9 KSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTP
400 410 420 430 440 450
530 540 550 560 570 580
pF1KE9 VYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVF
460 470 480 490 500 510
590 600 610 620 630 640
pF1KE9 QQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVR
520 530 540 550 560 570
650 660 670 680 690 700
pF1KE9 ELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVV
580 590 600 610 620 630
710 720 730 740 750 760
pF1KE9 QKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHV
640 650 660 670 680 690
770 780 790 800 810 820
pF1KE9 LWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEG
700 710 720 730 740 750
830 840 850
pF1KE9 SHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA
::::::::::::::::::::::::::::::::
XP_016 SHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA
760 770 780
>>NP_001158095 (OMIM: 606229) protein argonaute-2 isofor (825 aa)
initn: 4936 init1: 4936 opt: 4936 Z-score: 4562.3 bits: 855.2 E(85289): 0
Smith-Waterman score: 5556; 96.0% identity (96.0% similar) in 859 aa overlap (1-859:1-825)
10 20 30 40 50 60
pF1KE9 MYSGAGPALAPPAPPPPIQGYAFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MYSGAGPALAPPAPPPPIQGYAFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 IKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 GEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 FFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 KSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQES
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 GQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 TSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 GGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 AGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 GMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 PPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE9 PTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE9 NERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQ
::: :::::::::::::::::::::::
NP_001 NER----------------------------------GTSRPSHYHVLWDDNRFSSDELQ
730 740
790 800 810 820 830 840
pF1KE9 ILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQ
750 760 770 780 790 800
850
pF1KE9 ALAKAVQVHQDTLRTMYFA
:::::::::::::::::::
NP_001 ALAKAVQVHQDTLRTMYFA
810 820
>>NP_036331 (OMIM: 606228) protein argonaute-1 isoform 1 (857 aa)
initn: 4904 init1: 4904 opt: 4926 Z-score: 4552.9 bits: 853.5 E(85289): 0
Smith-Waterman score: 4926; 83.0% identity (93.9% similar) in 857 aa overlap (5-859:3-857)
10 20 30 40 50
pF1KE9 MYSGAGPA-LAPPAPPPPIQGYAFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYEL
:::. : : ::.: .:. : :: .:: :. ::: ::.::.::::::.::::.
NP_036 MEAGPSGAAAGAYLPPLQ-QVFQAPRRPGIGTVGKPIKLLANYFEVDIPKIDVYHYEV
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 DIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTL
::::.:::::::::.::.:::::: :::::::::.::.::.::. :::: ..:..:::.
NP_036 DIKPDKCPRRVNREVVEYMVQHFKPQIFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 PGEGKDRIFKVSIKWVSCVSLQALHDAL-SGRLPSVPFETIQALDVVMRHLPSMRYTPVG
:::::::::::::::.. :: . ::.:: ::..: ::.:..:::::.:::: ::::::::
NP_036 PGEGKDRIFKVSIKWLAIVSWRMLHEALVSGQIP-VPLESVQALDVAMRHLASMRYTPVG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 RSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVL
::::. :: .::::::::::::::::::..:::::::::::::::::::::::.::::
NP_036 RSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 DFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQ
:...:.:: :::::::::.:::::::::::.::::::::::::::::::::::::::::
NP_036 DIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE9 ESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTD
:::::::::::::::....: :.:::::::::::::::::::::::::::::::::::::
NP_036 ESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTD
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE9 NQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSI
:::::::.::::::::::::::.::..::.: :::..:::: :::.::.:::::: : .
NP_036 NQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPIL
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE9 LYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKIS
:::::.::::: :::::::.:::..:::::::::::::::.:: : ::.::.::::::
NP_036 QYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKIS
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE9 RDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDT
.:::::::::::::::::::::::::::::::::.::::..:::::::::::::::::::
NP_036 KDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDT
480 490 500 510 520 530
540 550 560 570 580 590
pF1KE9 VLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADV
.:::::::::.::: .:.:::::::::::::::::.::::.:. : :::::::::::::
NP_036 LLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADV
540 550 560 570 580 590
600 610 620 630 640 650
pF1KE9 THPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTR
:::::::::::::.::::::::::.:::::::::. :::::.::. ::::::::::::::
NP_036 THPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTR
600 610 620 630 640 650
660 670 680 690 700 710
pF1KE9 FKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCT
::::::::::::: :::. :.::.::::::.::::::::::::::.:::::::::::::.
NP_036 FKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCA
660 670 680 690 700 710
720 730 740 750 760 770
pF1KE9 DKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDE
:::::.::::::::::::::.:::: :::::::::::::::::::::.::::::::..::
NP_036 DKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADE
720 730 740 750 760 770
780 790 800 810 820 830
pF1KE9 LQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRD
::::::::::::::::::::::::::::.:::::::::::::::::.:::: ::::::::
NP_036 LQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRD
780 790 800 810 820 830
840 850
pF1KE9 HQALAKAVQVHQDTLRTMYFA
::::::::::::::::::::
NP_036 PQALAKAVQVHQDTLRTMYFA
840 850
>>NP_001304051 (OMIM: 606228) protein argonaute-1 isofor (891 aa)
initn: 4904 init1: 4904 opt: 4926 Z-score: 4552.6 bits: 853.5 E(85289): 0
Smith-Waterman score: 4926; 83.0% identity (93.9% similar) in 857 aa overlap (5-859:3-857)
10 20 30 40 50
pF1KE9 MYSGAGPA-LAPPAPPPPIQGYAFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYEL
:::. : : ::.: .:. : :: .:: :. ::: ::.::.::::::.::::.
NP_001 MEAGPSGAAAGAYLPPLQ-QVFQAPRRPGIGTVGKPIKLLANYFEVDIPKIDVYHYEV
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 DIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTL
::::.:::::::::.::.:::::: :::::::::.::.::.::. :::: ..:..:::.
NP_001 DIKPDKCPRRVNREVVEYMVQHFKPQIFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 PGEGKDRIFKVSIKWVSCVSLQALHDAL-SGRLPSVPFETIQALDVVMRHLPSMRYTPVG
:::::::::::::::.. :: . ::.:: ::..: ::.:..:::::.:::: ::::::::
NP_001 PGEGKDRIFKVSIKWLAIVSWRMLHEALVSGQIP-VPLESVQALDVAMRHLASMRYTPVG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 RSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVL
::::. :: .::::::::::::::::::..:::::::::::::::::::::::.::::
NP_001 RSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 DFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQ
:...:.:: :::::::::.:::::::::::.::::::::::::::::::::::::::::
NP_001 DIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE9 ESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTD
:::::::::::::::....: :.:::::::::::::::::::::::::::::::::::::
NP_001 ESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTD
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE9 NQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSI
:::::::.::::::::::::::.::..::.: :::..:::: :::.::.:::::: : .
NP_001 NQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPIL
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE9 LYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKIS
:::::.::::: :::::::.:::..:::::::::::::::.:: : ::.::.::::::
NP_001 QYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKIS
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE9 RDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDT
.:::::::::::::::::::::::::::::::::.::::..:::::::::::::::::::
NP_001 KDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDT
480 490 500 510 520 530
540 550 560 570 580 590
pF1KE9 VLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADV
.:::::::::.::: .:.:::::::::::::::::.::::.:. : :::::::::::::
NP_001 LLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADV
540 550 560 570 580 590
600 610 620 630 640 650
pF1KE9 THPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTR
:::::::::::::.::::::::::.:::::::::. :::::.::. ::::::::::::::
NP_001 THPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTR
600 610 620 630 640 650
660 670 680 690 700 710
pF1KE9 FKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCT
::::::::::::: :::. :.::.::::::.::::::::::::::.:::::::::::::.
NP_001 FKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCA
660 670 680 690 700 710
720 730 740 750 760 770
pF1KE9 DKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDE
:::::.::::::::::::::.:::: :::::::::::::::::::::.::::::::..::
NP_001 DKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADE
720 730 740 750 760 770
780 790 800 810 820 830
pF1KE9 LQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRD
::::::::::::::::::::::::::::.:::::::::::::::::.:::: ::::::::
NP_001 LQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRD
780 790 800 810 820 830
840 850
pF1KE9 HQALAKAVQVHQDTLRTMYFA
::::::::::::::::::::
NP_001 PQALAKAVQVHQDTLRTMYFAXRQNAVTSLDRRKLSKPQELCHPNPEEARRREVG
840 850 860 870 880 890
>>XP_011539538 (OMIM: 606228) PREDICTED: protein argonau (860 aa)
initn: 2674 init1: 2674 opt: 4910 Z-score: 4538.0 bits: 850.8 E(85289): 0
Smith-Waterman score: 4910; 82.7% identity (93.6% similar) in 860 aa overlap (5-859:3-860)
10 20 30 40 50
pF1KE9 MYSGAGPA-LAPPAPPPPIQGYAFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYEL
:::. : : ::.: .:. : :: .:: :. ::: ::.::.::::::.::::.
XP_011 MEAGPSGAAAGAYLPPLQ-QVFQAPRRPGIGTVGKPIKLLANYFEVDIPKIDVYHYEV
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 DIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTL
::::.:::::::::.::.:::::: :::::::::.::.::.::. :::: ..:..:::.
XP_011 DIKPDKCPRRVNREVVEYMVQHFKPQIFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 PGEGKDRIFKVSIKWVSCVSLQALHDAL-SGRLPSVPFETIQALDVVMRHLPSMRYTPVG
:::::::::::::::.. :: . ::.:: ::..: ::.:..:::::.:::: ::::::::
XP_011 PGEGKDRIFKVSIKWLAIVSWRMLHEALVSGQIP-VPLESVQALDVAMRHLASMRYTPVG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 RSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVL
::::. :: .::::::::::::::::::..:::::::::::::::::::::::.::::
XP_011 RSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 DFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQ
:...:.:: :::::::::.:::::::::::.::::::::::::::::::::::::::::
XP_011 DIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE9 ESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTD
:::::::::::::::....: :.:::::::::::::::::::::::::::::::::::::
XP_011 ESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTD
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE9 NQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSI
:::::::.::::::::::::::.::..::.: :::..:::: :::.::.:::::: : .
XP_011 NQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPIL
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE9 LYGGR---NKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLR
:::: :.::::: :::::::.:::..:::::::::::::::.:: : ::.::.:::
XP_011 QYGGRVSRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLR
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE9 KISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRV
:::.:::::::::::::::::::::::::::::::::.::::..::::::::::::::::
XP_011 KISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRV
480 490 500 510 520 530
540 550 560 570 580 590
pF1KE9 GDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLG
:::.:::::::::.::: .:.:::::::::::::::::.::::.:. : ::::::::::
XP_011 GDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLG
540 550 560 570 580 590
600 610 620 630 640 650
pF1KE9 ADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYK
::::::::::::::::.::::::::::.:::::::::. :::::.::. :::::::::::
XP_011 ADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYK
600 610 620 630 640 650
660 670 680 690 700 710
pF1KE9 STRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRL
:::::::::::::::: :::. :.::.::::::.::::::::::::::.:::::::::::
XP_011 STRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRL
660 670 680 690 700 710
720 730 740 750 760 770
pF1KE9 FCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFS
::.:::::.::::::::::::::.:::: :::::::::::::::::::::.::::::::.
XP_011 FCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFT
720 730 740 750 760 770
780 790 800 810 820 830
pF1KE9 SDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSN
.::::::::::::::::::::::::::::::.:::::::::::::::::.:::: :::::
XP_011 ADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSN
780 790 800 810 820 830
840 850
pF1KE9 GRDHQALAKAVQVHQDTLRTMYFA
::: ::::::::::::::::::::
XP_011 GRDPQALAKAVQVHQDTLRTMYFA
840 850 860
>>NP_001304052 (OMIM: 606228) protein argonaute-1 isofor (782 aa)
initn: 4594 init1: 4594 opt: 4607 Z-score: 4258.8 bits: 798.9 E(85289): 0
Smith-Waterman score: 4607; 84.8% identity (95.1% similar) in 783 aa overlap (78-859:1-782)
50 60 70 80 90 100
pF1KE9 DIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLP
:::::: :::::::::.::.::.::. ::
NP_001 MVQHFKPQIFGDRKPVYDGKKNIYTVTALP
10 20 30
110 120 130 140 150 160
pF1KE9 IGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDAL-SGRLPSVPFETIQALDVVM
:: ..:..:::.:::::::::::::::.. :: . ::.:: ::..: ::.:..:::::.:
NP_001 IGNERVDFEVTIPGEGKDRIFKVSIKWLAIVSWRMLHEALVSGQIP-VPLESVQALDVAM
40 50 60 70 80
170 180 190 200 210 220
pF1KE9 RHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYK
::: ::::::::::::. :: .::::::::::::::::::..::::::::::::::::
NP_001 RHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYK
90 100 110 120 130 140
230 240 250 260 270 280
pF1KE9 AQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTR
:::::::.:::::...:.:: :::::::::.:::::::::::.:::::::::::::::::
NP_001 AQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTR
150 160 170 180 190 200
290 300 310 320 330 340
pF1KE9 RPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNI
::::::::::: :::::::::::::::....: :.:::::::::::::::::::::::::
NP_001 RPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNI
210 220 230 240 250 260
350 360 370 380 390 400
pF1KE9 VAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMT
:::::::::::::::::::.::::::::::::::.::..::.: :::..:::: :::.::
NP_001 VAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMT
270 280 290 300 310 320
410 420 430 440 450 460
pF1KE9 DVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVH
.:::::: : . :::::.::::: :::::::.:::..:::::::::::::::.:: :
NP_001 EVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEV
330 340 350 360 370 380
470 480 490 500 510 520
pF1KE9 LKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKT
::.::.::::::.:::::::::::::::::::::::::::::::::.::::..:::::::
NP_001 LKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKT
390 400 410 420 430 440
530 540 550 560 570 580
pF1KE9 PVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPV
::::::::::::.:::::::::.::: .:.:::::::::::::::::.::::.:. : :
NP_001 PVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAV
450 460 470 480 490 500
590 600 610 620 630 640
pF1KE9 FQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMV
:::::::::::::::::::::::::.::::::::::.:::::::::. :::::.::. ::
NP_001 FQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMV
510 520 530 540 550 560
650 660 670 680 690 700
pF1KE9 RELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIV
::::::::::::::::::::::::: :::. :.::.::::::.::::::::::::::.::
NP_001 RELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIV
570 580 590 600 610 620
710 720 730 740 750 760
pF1KE9 VQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYH
:::::::::::.:::::.::::::::::::::.:::: :::::::::::::::::::::.
NP_001 VQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYY
630 640 650 660 670 680
770 780 790 800 810 820
pF1KE9 VLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAE
::::::::..::::::::::::::::::::::::::::::.:::::::::::::::::.:
NP_001 VLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGE
690 700 710 720 730 740
830 840 850
pF1KE9 GSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA
::: :::::::: ::::::::::::::::::::
NP_001 GSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA
750 760 770 780
859 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 09:37:23 2016 done: Sun Nov 6 09:37:25 2016
Total Scan time: 11.010 Total Display time: 0.290
Function used was FASTA [36.3.4 Apr, 2011]