Result of FASTA (omim) for pF1KE2422
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE2422, 216 aa
  1>>>pF1KE2422 216 - 216 aa - 216 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.1765+/-0.000351; mu= 14.0296+/- 0.022
 mean_var=60.0394+/-11.839, 0's: 0 Z-trim(112.5): 25  B-trim: 0 in 0/53
 Lambda= 0.165522
 statistics sampled from 21359 (21384) to 21359 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.644), E-opt: 0.2 (0.251), width:  16
 Scan time:  4.600

The best scores are:                                      opt bits E(85289)
NP_775739 (OMIM: 609282) MOB kinase activator 1B i ( 216) 1465 358.2   6e-99
NP_001231695 (OMIM: 609282) MOB kinase activator 1 ( 221) 1432 350.3 1.4e-96
XP_005265766 (OMIM: 609282) PREDICTED: MOB kinase  ( 221) 1432 350.3 1.4e-96
XP_011530714 (OMIM: 609282) PREDICTED: MOB kinase  ( 240) 1432 350.3 1.5e-96
XP_016864326 (OMIM: 609282) PREDICTED: MOB kinase  ( 247) 1432 350.3 1.6e-96
NP_060691 (OMIM: 609281) MOB kinase activator 1A i ( 216) 1412 345.5 3.9e-95
NP_001304039 (OMIM: 609281) MOB kinase activator 1 ( 215) 1400 342.7 2.8e-94
NP_001304040 (OMIM: 609281) MOB kinase activator 1 ( 258) 1379 337.7 1.1e-92
NP_001231696 (OMIM: 609282) MOB kinase activator 1 ( 147)  947 234.4 7.4e-62
NP_001304041 (OMIM: 609281) MOB kinase activator 1 ( 138)  916 227.0 1.2e-59
XP_011531250 (OMIM: 609281) PREDICTED: MOB kinase  ( 180)  883 219.2 3.5e-57
NP_443731 (OMIM: 611969) MOB kinase activator 2 is ( 237)  555 140.9 1.7e-33
NP_001165694 (OMIM: 611969) MOB kinase activator 2 ( 268)  551 140.0 3.6e-33
NP_001191023 (OMIM: 609361) MOB-like protein phoce ( 193)  193 54.4 1.5e-07
NP_955776 (OMIM: 609361) MOB-like protein phocein  ( 193)  193 54.4 1.5e-07
NP_001094289 (OMIM: 609361) MOB-like protein phoce ( 204)  193 54.4 1.6e-07
NP_056202 (OMIM: 609361) MOB-like protein phocein  ( 225)  193 54.4 1.7e-07


>>NP_775739 (OMIM: 609282) MOB kinase activator 1B isofo  (216 aa)
 initn: 1465 init1: 1465 opt: 1465  Z-score: 1897.5  bits: 358.2 E(85289): 6e-99
Smith-Waterman score: 1465; 100.0% identity (100.0% similar) in 216 aa overlap (1-216:1-216)

               10        20        30        40        50        60
pF1KE2 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 TVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 TVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 WVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 WVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLN
              130       140       150       160       170       180

              190       200       210      
pF1KE2 TSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
       ::::::::::::::::::::::::::::::::::::
NP_775 TSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
              190       200       210      

>>NP_001231695 (OMIM: 609282) MOB kinase activator 1B is  (221 aa)
 initn: 1432 init1: 1432 opt: 1432  Z-score: 1854.7  bits: 350.3 E(85289): 1.4e-96
Smith-Waterman score: 1432; 100.0% identity (100.0% similar) in 211 aa overlap (6-216:11-221)

                    10        20        30        40        50     
pF1KE2      MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNE
                 ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEGATDVNESGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNE
               10        20        30        40        50        60

          60        70        80        90       100       110     
pF1KE2 WVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYI
               70        80        90       100       110       120

         120       130       140       150       160       170     
pF1KE2 DYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQE
              130       140       150       160       170       180

         180       190       200       210      
pF1KE2 EAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
       :::::::::::::::::::::::::::::::::::::::::
NP_001 EAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
              190       200       210       220 

>>XP_005265766 (OMIM: 609282) PREDICTED: MOB kinase acti  (221 aa)
 initn: 1432 init1: 1432 opt: 1432  Z-score: 1854.7  bits: 350.3 E(85289): 1.4e-96
Smith-Waterman score: 1432; 100.0% identity (100.0% similar) in 211 aa overlap (6-216:11-221)

                    10        20        30        40        50     
pF1KE2      MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNE
                 ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEGATDVNESGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNE
               10        20        30        40        50        60

          60        70        80        90       100       110     
pF1KE2 WVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYI
               70        80        90       100       110       120

         120       130       140       150       160       170     
pF1KE2 DYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQE
              130       140       150       160       170       180

         180       190       200       210      
pF1KE2 EAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
       :::::::::::::::::::::::::::::::::::::::::
XP_005 EAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
              190       200       210       220 

>>XP_011530714 (OMIM: 609282) PREDICTED: MOB kinase acti  (240 aa)
 initn: 1432 init1: 1432 opt: 1432  Z-score: 1854.2  bits: 350.3 E(85289): 1.5e-96
Smith-Waterman score: 1432; 100.0% identity (100.0% similar) in 211 aa overlap (6-216:30-240)

                                       10        20        30      
pF1KE2                         MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATL
                                    :::::::::::::::::::::::::::::::
XP_011 MTPNRVDRGAGQPRRTRWASSLAAEETRSGSRSSKTFKPKKNIPEGSHQYELLKHAEATL
               10        20        30        40        50        60

         40        50        60        70        80        90      
pF1KE2 GSGNLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSGNLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYH
               70        80        90       100       110       120

        100       110       120       130       140       150      
pF1KE2 WADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLF
              130       140       150       160       170       180

        160       170       180       190       200       210      
pF1KE2 RVYAHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVYAHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
              190       200       210       220       230       240

>>XP_016864326 (OMIM: 609282) PREDICTED: MOB kinase acti  (247 aa)
 initn: 1432 init1: 1432 opt: 1432  Z-score: 1854.0  bits: 350.3 E(85289): 1.6e-96
Smith-Waterman score: 1432; 100.0% identity (100.0% similar) in 211 aa overlap (6-216:37-247)

                                        10        20        30     
pF1KE2                          MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEAT
                                     ::::::::::::::::::::::::::::::
XP_016 TTANCSFDFPGSGDPFISNPLPATSSWYYSGSRSSKTFKPKKNIPEGSHQYELLKHAEAT
         10        20        30        40        50        60      

          40        50        60        70        80        90     
pF1KE2 LGSGNLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGSGNLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEY
         70        80        90       100       110       120      

         100       110       120       130       140       150     
pF1KE2 HWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRL
        130       140       150       160       170       180      

         160       170       180       190       200       210     
pF1KE2 FRVYAHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRVYAHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKD
        190       200       210       220       230       240      

        
pF1KE2 R
       :
XP_016 R
        

>>NP_060691 (OMIM: 609281) MOB kinase activator 1A isofo  (216 aa)
 initn: 1412 init1: 1412 opt: 1412  Z-score: 1829.1  bits: 345.5 E(85289): 3.9e-95
Smith-Waterman score: 1412; 95.8% identity (98.6% similar) in 216 aa overlap (1-216:1-216)

               10        20        30        40        50        60
pF1KE2 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVN
       :::::.::::::::::::::::::::::::::::::::::::.:::::::::::::.:::
NP_060 MSFLFSSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRQAVMLPEGEDLNEWIAVN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 TVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMT
       ::::::::::::::::.:::: :::::::::.::::::::::::::::::::::::::::
NP_060 TVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 WVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLN
       :::::::::::::::::::::::::::::::::::::::::::::::: :.:::::::::
NP_060 WVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLN
              130       140       150       160       170       180

              190       200       210      
pF1KE2 TSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
       ::::::::::::::::::::::::::::::: ::::
NP_060 TSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR
              190       200       210      

>>NP_001304039 (OMIM: 609281) MOB kinase activator 1A is  (215 aa)
 initn: 1379 init1: 1379 opt: 1400  Z-score: 1813.6  bits: 342.7 E(85289): 2.8e-94
Smith-Waterman score: 1400; 95.8% identity (98.1% similar) in 216 aa overlap (1-216:1-215)

               10        20        30        40        50        60
pF1KE2 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVN
       ::::: ::::::::::::::::::::::::::::::::::::.:::::::::::::.:::
NP_001 MSFLF-SRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRQAVMLPEGEDLNEWIAVN
                10        20        30        40        50         

               70        80        90       100       110       120
pF1KE2 TVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMT
       ::::::::::::::::.:::: :::::::::.::::::::::::::::::::::::::::
NP_001 TVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMT
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KE2 WVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLN
       :::::::::::::::::::::::::::::::::::::::::::::::: :.:::::::::
NP_001 WVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLN
     120       130       140       150       160       170         

              190       200       210      
pF1KE2 TSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
       ::::::::::::::::::::::::::::::: ::::
NP_001 TSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR
     180       190       200       210     

>>NP_001304040 (OMIM: 609281) MOB kinase activator 1A is  (258 aa)
 initn: 1379 init1: 1379 opt: 1379  Z-score: 1785.3  bits: 337.7 E(85289): 1.1e-92
Smith-Waterman score: 1379; 96.2% identity (98.6% similar) in 210 aa overlap (7-216:49-258)

                                       10        20        30      
pF1KE2                         MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATL
                                     ::::::::::::::::::::::::::::::
NP_001 CWPWSRIVLSSSDSAHLLALILTNFSCPRSSRSSKTFKPKKNIPEGSHQYELLKHAEATL
       20        30        40        50        60        70        

         40        50        60        70        80        90      
pF1KE2 GSGNLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYH
       ::::::.:::::::::::::.:::::::::::::::::::.:::: :::::::::.::::
NP_001 GSGNLRQAVMLPEGEDLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYH
       80        90       100       110       120       130        

        100       110       120       130       140       150      
pF1KE2 WADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLF
      140       150       160       170       180       190        

        160       170       180       190       200       210      
pF1KE2 RVYAHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
       :::::::::::: :.:::::::::::::::::::::::::::::::::::::::: ::::
NP_001 RVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR
      200       210       220       230       240       250        

>>NP_001231696 (OMIM: 609282) MOB kinase activator 1B is  (147 aa)
 initn: 969 init1: 947 opt: 947  Z-score: 1231.5  bits: 234.4 E(85289): 7.4e-62
Smith-Waterman score: 947; 99.3% identity (100.0% similar) in 138 aa overlap (1-138:1-138)

               10        20        30        40        50        60
pF1KE2 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 TVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 WVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLN
       :::::::::::::::::.                                          
NP_001 WVQDQLDDETLFPSKIGIINFCKGDPS                                 
              130       140                                        

>>NP_001304041 (OMIM: 609281) MOB kinase activator 1A is  (138 aa)
 initn: 916 init1: 916 opt: 916  Z-score: 1191.9  bits: 227.0 E(85289): 1.2e-59
Smith-Waterman score: 916; 95.7% identity (99.3% similar) in 138 aa overlap (1-138:1-138)

               10        20        30        40        50        60
pF1KE2 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVN
       :::::.::::::::::::::::::::::::::::::::::::.:::::::::::::.:::
NP_001 MSFLFSSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRQAVMLPEGEDLNEWIAVN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 TVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMT
       ::::::::::::::::.:::: :::::::::.::::::::::::::::::::::::::::
NP_001 TVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 WVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLN
       ::::::::::::::::::                                          
NP_001 WVQDQLDDETLFPSKIGV                                          
              130                                                  




216 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon Nov  7 19:39:27 2016 done: Mon Nov  7 19:39:28 2016
 Total Scan time:  4.600 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]
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