Result of FASTA (omim) for pF1KE6772
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE6772, 613 aa
  1>>>pF1KE6772     613 - 613 aa - 613 aa
Library: /omim/omim.rfq.tfa
  64704883 residues in 91410 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.6450+/-0.000342; mu= 17.9466+/- 0.021
 mean_var=74.7050+/-15.263, 0's: 0 Z-trim(114.2): 23  B-trim: 229 in 2/56
 Lambda= 0.148388
 statistics sampled from 24676 (24699) to 24676 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.632), E-opt: 0.2 (0.27), width:  16
 Scan time:  5.080

The best scores are:                                      opt bits E(91410)
NP_004199 (OMIM: 300169,300614,300816,310490,31049 ( 613) 4029 872.2       0
NP_665811 (OMIM: 300169,300614,300816,310490,31049 ( 609) 3788 820.6       0
NP_001124319 (OMIM: 300169,300614,300816,310490,31 ( 324) 2110 461.2 2.7e-129
NP_001124318 (OMIM: 300169,300614,300816,310490,31 ( 274) 1811 397.2 4.3e-110
NP_001018070 (OMIM: 617298) apoptosis-inducing fac ( 598)  285 70.6 1.8e-11
NP_001139760 (OMIM: 617298) apoptosis-inducing fac ( 604)  285 70.7 1.8e-11
NP_653305 (OMIM: 617298) apoptosis-inducing factor ( 605)  285 70.7 1.8e-11
NP_000628 (OMIM: 138300) glutathione reductase, mi ( 522)  154 42.6  0.0045


>>NP_004199 (OMIM: 300169,300614,300816,310490,310490) a  (613 aa)
 initn: 4029 init1: 4029 opt: 4029  Z-score: 4659.0  bits: 872.2 E(91410):    0
Smith-Waterman score: 4029; 100.0% identity (100.0% similar) in 613 aa overlap (1-613:1-613)

               10        20        30        40        50        60
pF1KE6 MFRCGGLAAGALKQKLVPLVRTVCVRSPRQRNRLPGNLFQRWHVPLELQMTRQMASSGAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MFRCGGLAAGALKQKLVPLVRTVCVRSPRQRNRLPGNLFQRWHVPLELQMTRQMASSGAS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE6 GGKIDNSVLVLIVGLSTVGAGAYAYKTMKEDEKRYNERISGLGLTPEQKQKKAALSASEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GGKIDNSVLVLIVGLSTVGAGAYAYKTMKEDEKRYNERISGLGLTPEQKQKKAALSASEG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE6 EEVPQDKAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EEVPQDKAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELW
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE6 FSDDPNVTKTLRFKQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FSDDPNVTKTLRFKQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE6 NMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISREV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISREV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE6 KSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE6 VKVMPNAIVQSVGVSSGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VKVMPNAIVQSVGVSSGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE6 FRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE6 MFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTGIRSESETESEASE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTGIRSESETESEASE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE6 ITIPPSTPAVPQAPVQGEDYGKGVIFYLRDKVVVGIVLWNIFNRMPIARKIIKDGEQHED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ITIPPSTPAVPQAPVQGEDYGKGVIFYLRDKVVVGIVLWNIFNRMPIARKIIKDGEQHED
              550       560       570       580       590       600

              610   
pF1KE6 LNEVAKLFNIHED
       :::::::::::::
NP_004 LNEVAKLFNIHED
              610   

>>NP_665811 (OMIM: 300169,300614,300816,310490,310490) a  (609 aa)
 initn: 3713 init1: 3487 opt: 3788  Z-score: 4380.2  bits: 820.6 E(91410):    0
Smith-Waterman score: 3788; 95.1% identity (97.1% similar) in 614 aa overlap (1-613:1-609)

               10        20        30        40        50        60
pF1KE6 MFRCGGLAAGALKQKLVPLVRTVCVRSPRQRNRLPGNLFQRWHVPLELQMTRQMASSGAS
       :::::::::::::::::::::::::::::::::::  . :  :.    . .:..::.:::
NP_665 MFRCGGLAAGALKQKLVPLVRTVCVRSPRQRNRLP--VVQSHHLG---SPSRSLASTGAS
               10        20        30          40           50     

               70        80         90       100       110         
pF1KE6 GGKIDNSVLVLIVGLSTVGAGAY-AYKTMKEDEKRYNERISGLGLTPEQKQKKAALSASE
       :   .: :  :::: ...:::.: ::::::::::::::::::::::::::::::::::::
NP_665 GKDGSNLVYFLIVGATVTGAGVYYAYKTMKEDEKRYNERISGLGLTPEQKQKKAALSASE
          60        70        80        90       100       110     

     120       130       140       150       160       170         
pF1KE6 GEEVPQDKAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 GEEVPQDKAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKEL
         120       130       140       150       160       170     

     180       190       200       210       220       230         
pF1KE6 WFSDDPNVTKTLRFKQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 WFSDDPNVTKTLRFKQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVR
         180       190       200       210       220       230     

     240       250       260       270       280       290         
pF1KE6 DNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 DNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISRE
         240       250       260       270       280       290     

     300       310       320       330       340       350         
pF1KE6 VKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 VKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRRE
         300       310       320       330       340       350     

     360       370       380       390       400       410         
pF1KE6 GVKVMPNAIVQSVGVSSGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 GVKVMPNAIVQSVGVSSGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFG
         360       370       380       390       400       410     

     420       430       440       450       460       470         
pF1KE6 GFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 GFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQ
         420       430       440       450       460       470     

     480       490       500       510       520       530         
pF1KE6 SMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTGIRSESETESEAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 SMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTGIRSESETESEAS
         480       490       500       510       520       530     

     540       550       560       570       580       590         
pF1KE6 EITIPPSTPAVPQAPVQGEDYGKGVIFYLRDKVVVGIVLWNIFNRMPIARKIIKDGEQHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 EITIPPSTPAVPQAPVQGEDYGKGVIFYLRDKVVVGIVLWNIFNRMPIARKIIKDGEQHE
         540       550       560       570       580       590     

     600       610   
pF1KE6 DLNEVAKLFNIHED
       ::::::::::::::
NP_665 DLNEVAKLFNIHED
         600         

>>NP_001124319 (OMIM: 300169,300614,300816,310490,310490  (324 aa)
 initn: 2110 init1: 2110 opt: 2110  Z-score: 2442.9  bits: 461.2 E(91410): 2.7e-129
Smith-Waterman score: 2110; 100.0% identity (100.0% similar) in 322 aa overlap (1-322:1-322)

               10        20        30        40        50        60
pF1KE6 MFRCGGLAAGALKQKLVPLVRTVCVRSPRQRNRLPGNLFQRWHVPLELQMTRQMASSGAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFRCGGLAAGALKQKLVPLVRTVCVRSPRQRNRLPGNLFQRWHVPLELQMTRQMASSGAS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE6 GGKIDNSVLVLIVGLSTVGAGAYAYKTMKEDEKRYNERISGLGLTPEQKQKKAALSASEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGKIDNSVLVLIVGLSTVGAGAYAYKTMKEDEKRYNERISGLGLTPEQKQKKAALSASEG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE6 EEVPQDKAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEVPQDKAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELW
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE6 FSDDPNVTKTLRFKQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSDDPNVTKTLRFKQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE6 NMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISREV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISREV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE6 KSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREG
       ::::::::::::::::::::::                                      
NP_001 KSITIIGGGFLGSELACALGRKDI                                    
              310       320                                        

>>NP_001124318 (OMIM: 300169,300614,300816,310490,310490  (274 aa)
 initn: 1811 init1: 1811 opt: 1811  Z-score: 2098.1  bits: 397.2 E(91410): 4.3e-110
Smith-Waterman score: 1811; 100.0% identity (100.0% similar) in 274 aa overlap (340-613:1-274)

     310       320       330       340       350       360         
pF1KE6 FLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVMPNAIV
                                     ::::::::::::::::::::::::::::::
NP_001                               MGKILPEYLSNWTMEKVRREGVKVMPNAIV
                                             10        20        30

     370       380       390       400       410       420         
pF1KE6 QSVGVSSGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSVGVSSGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQA
               40        50        60        70        80        90

     430       440       450       460       470       480         
pF1KE6 RSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPD
              100       110       120       130       140       150

     490       500       510       520       530       540         
pF1KE6 VGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTGIRSESETESEASEITIPPSTPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTGIRSESETESEASEITIPPSTPA
              160       170       180       190       200       210

     550       560       570       580       590       600         
pF1KE6 VPQAPVQGEDYGKGVIFYLRDKVVVGIVLWNIFNRMPIARKIIKDGEQHEDLNEVAKLFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPQAPVQGEDYGKGVIFYLRDKVVVGIVLWNIFNRMPIARKIIKDGEQHEDLNEVAKLFN
              220       230       240       250       260       270

     610   
pF1KE6 IHED
       ::::
NP_001 IHED
           

>>NP_001018070 (OMIM: 617298) apoptosis-inducing factor   (598 aa)
 initn: 234 init1: 127 opt: 285  Z-score: 327.4  bits: 70.6 E(91410): 1.8e-11
Smith-Waterman score: 396; 26.7% identity (57.0% similar) in 419 aa overlap (83-496:152-528)

             60        70        80        90       100       110  
pF1KE6 QMASSGASGGKIDNSVLVLIVGLSTVGAGAYAYKTMKEDEKRYNERISGLGLTPEQKQKK
                                     . ...  : :: :  : :  .:  ... : 
NP_001 SRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVYV-RASKQALQLQRRTKV
             130       140       150       160        170       180

            120       130       140       150       160       170  
pF1KE6 AALSASEGEEVPQDKAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMR
        :   :     :.    : .  :..:.:.:... :...: .  . :... . : .::: :
NP_001 MAKCIS-----PSAGYSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDR
                   190       200       210       220       230     

            180       190       200       210       220       230  
pF1KE6 PPLSKELWFSDDPNVTKTLRFKQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKK
       : ::: :                 . . ... ..:  :. .          :. :::  .
NP_001 PKLSKSL-----------------DTQPEQLALRPKEFFRAY---------GIEVLTEAQ
         240                        250       260                  

            240       250       260       270       280       290  
pF1KE6 VVQLDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRS
       :: .::: . : ..:: .. : : :.: :..:..::     : ::..  :. :   :   
NP_001 VVTVDVRTKKVVFKDGFKLEYSKLLLAPGSSPKTLSC---KGKEVENVFTI-RTPEDANR
     270       280       290       300          310        320     

            300       310       320       330       340       350  
pF1KE6 LEKISREVKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWT
       . ...:  ......:.:::: :.:  : .::....  :..:  :.  . ..: : ..   
NP_001 VVRLARG-RNVVVVGAGFLGMEVAAYLTEKAHSVS--VVEL--EETPFRRFLGERVGRAL
         330        340       350         360         370       380

            360       370       380        390       400       410 
pF1KE6 MEKVRREGVKVMPNAIVQSVGVSSGKLL-IKLKDGRKVETDHIVAAVGLEPNVELAKTGG
       :.  . . :: . .. :. .  . :::  . ::... :..:  :...:  : . . . .:
NP_001 MKMFENNRVKFYMQTEVSELRGQEGKLKEVVLKSSKVVRADVCVVGIGAVPATGFLRQSG
              390       400       410       420       430       440

             420       430        440       450         460        
pF1KE6 LEIDSDFGGFRVNAELQAR-SNIWVAGDAACFYDIKLGRRRVE--HHDHAVVSGRLAGEN
       . .::  : . ::  .:.   ....::::. :     . :.:.  : . : ..::.:..:
NP_001 IGLDSR-GFIPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQN
               450       460       470       480       490         

      470       480        490       500       510       520       
pF1KE6 MTGAAKPYWHQSMFWSDL-GPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTG
       : .    .    ..:. . : .. : . :                               
NP_001 MLAQEAEMSTVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDLEELKFVAFYTKGDEVIAVA
     500       510       520       530       540       550         

>>NP_001139760 (OMIM: 617298) apoptosis-inducing factor   (604 aa)
 initn: 234 init1: 127 opt: 285  Z-score: 327.4  bits: 70.7 E(91410): 1.8e-11
Smith-Waterman score: 396; 26.7% identity (57.0% similar) in 419 aa overlap (83-496:158-534)

             60        70        80        90       100       110  
pF1KE6 QMASSGASGGKIDNSVLVLIVGLSTVGAGAYAYKTMKEDEKRYNERISGLGLTPEQKQKK
                                     . ...  : :: :  : :  .:  ... : 
NP_001 SRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVYV-RASKQALQLQRRTKV
       130       140       150       160       170        180      

            120       130       140       150       160       170  
pF1KE6 AALSASEGEEVPQDKAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMR
        :   :     :.    : .  :..:.:.:... :...: .  . :... . : .::: :
NP_001 MAKCIS-----PSAGYSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDR
        190            200       210       220       230       240 

            180       190       200       210       220       230  
pF1KE6 PPLSKELWFSDDPNVTKTLRFKQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKK
       : ::: :                 . . ... ..:  :. .          :. :::  .
NP_001 PKLSKSL-----------------DTQPEQLALRPKEFFRAY---------GIEVLTEAQ
                              250       260                270     

            240       250       260       270       280       290  
pF1KE6 VVQLDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRS
       :: .::: . : ..:: .. : : :.: :..:..::     : ::..  :. :   :   
NP_001 VVTVDVRTKKVVFKDGFKLEYSKLLLAPGSSPKTLSC---KGKEVENVFTI-RTPEDANR
         280       290       300       310          320        330 

            300       310       320       330       340       350  
pF1KE6 LEKISREVKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWT
       . ...:  ......:.:::: :.:  : .::....  :..:  :.  . ..: : ..   
NP_001 VVRLARG-RNVVVVGAGFLGMEVAAYLTEKAHSVS--VVEL--EETPFRRFLGERVGRAL
              340       350       360           370       380      

            360       370       380        390       400       410 
pF1KE6 MEKVRREGVKVMPNAIVQSVGVSSGKLL-IKLKDGRKVETDHIVAAVGLEPNVELAKTGG
       :.  . . :: . .. :. .  . :::  . ::... :..:  :...:  : . . . .:
NP_001 MKMFENNRVKFYMQTEVSELRGQEGKLKEVVLKSSKVVRADVCVVGIGAVPATGFLRQSG
        390       400       410       420       430       440      

             420       430        440       450         460        
pF1KE6 LEIDSDFGGFRVNAELQAR-SNIWVAGDAACFYDIKLGRRRVE--HHDHAVVSGRLAGEN
       . .::  : . ::  .:.   ....::::. :     . :.:.  : . : ..::.:..:
NP_001 IGLDSR-GFIPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQN
        450        460       470       480       490       500     

      470       480        490       500       510       520       
pF1KE6 MTGAAKPYWHQSMFWSDL-GPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTG
       : .    .    ..:. . : .. : . :                               
NP_001 MLAQEAEMSTVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDLEELKFVAFYTKGDEVIAVA
         510       520       530       540       550       560     

>>NP_653305 (OMIM: 617298) apoptosis-inducing factor 3 i  (605 aa)
 initn: 234 init1: 127 opt: 285  Z-score: 327.3  bits: 70.7 E(91410): 1.8e-11
Smith-Waterman score: 396; 26.7% identity (57.0% similar) in 419 aa overlap (83-496:152-528)

             60        70        80        90       100       110  
pF1KE6 QMASSGASGGKIDNSVLVLIVGLSTVGAGAYAYKTMKEDEKRYNERISGLGLTPEQKQKK
                                     . ...  : :: :  : :  .:  ... : 
NP_653 SRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVYV-RASKQALQLQRRTKV
             130       140       150       160        170       180

            120       130       140       150       160       170  
pF1KE6 AALSASEGEEVPQDKAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMR
        :   :     :.    : .  :..:.:.:... :...: .  . :... . : .::: :
NP_653 MAKCIS-----PSAGYSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDR
                   190       200       210       220       230     

            180       190       200       210       220       230  
pF1KE6 PPLSKELWFSDDPNVTKTLRFKQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKK
       : ::: :                 . . ... ..:  :. .          :. :::  .
NP_653 PKLSKSL-----------------DTQPEQLALRPKEFFRAY---------GIEVLTEAQ
         240                        250       260                  

            240       250       260       270       280       290  
pF1KE6 VVQLDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRS
       :: .::: . : ..:: .. : : :.: :..:..::     : ::..  :. :   :   
NP_653 VVTVDVRTKKVVFKDGFKLEYSKLLLAPGSSPKTLSC---KGKEVENVFTI-RTPEDANR
     270       280       290       300          310        320     

            300       310       320       330       340       350  
pF1KE6 LEKISREVKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWT
       . ...:  ......:.:::: :.:  : .::....  :..:  :.  . ..: : ..   
NP_653 VVRLARG-RNVVVVGAGFLGMEVAAYLTEKAHSVS--VVEL--EETPFRRFLGERVGRAL
         330        340       350         360         370       380

            360       370       380        390       400       410 
pF1KE6 MEKVRREGVKVMPNAIVQSVGVSSGKLL-IKLKDGRKVETDHIVAAVGLEPNVELAKTGG
       :.  . . :: . .. :. .  . :::  . ::... :..:  :...:  : . . . .:
NP_653 MKMFENNRVKFYMQTEVSELRGQEGKLKEVVLKSSKVVRADVCVVGIGAVPATGFLRQSG
              390       400       410       420       430       440

             420       430        440       450         460        
pF1KE6 LEIDSDFGGFRVNAELQAR-SNIWVAGDAACFYDIKLGRRRVE--HHDHAVVSGRLAGEN
       . .::  : . ::  .:.   ....::::. :     . :.:.  : . : ..::.:..:
NP_653 IGLDSR-GFIPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQN
               450       460       470       480       490         

      470       480        490       500       510       520       
pF1KE6 MTGAAKPYWHQSMFWSDL-GPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTG
       : .    .    ..:. . : .. : . :                               
NP_653 MLAQEAEMSTVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDLEELKFVAFYTKGDEVIAVA
     500       510       520       530       540       550         

>>NP_000628 (OMIM: 138300) glutathione reductase, mitoch  (522 aa)
 initn:  92 init1:  60 opt: 154  Z-score: 176.7  bits: 42.6 E(91410): 0.0045
Smith-Waterman score: 172; 25.1% identity (51.8% similar) in 371 aa overlap (102-441:27-377)

              80        90       100       110          120        
pF1KE6 IVGLSTVGAGAYAYKTMKEDEKRYNERISGLGLTPEQKQKKAALS---ASEGEEVPQDKA
                                     : : ::      :::   : . :  ::   
NP_000     MALLPRALSAGAGPSWRRAARAFRGFLLLLPEPAALTRALSRAMACRQEPQPQGPP
                   10        20        30        40        50      

      130            140       150       160       170             
pF1KE6 PS-----HVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLS----KEL
       :.        .:.::::....:.::  :: . :::. .: :. .:      ..    : .
NP_000 PAAGAVASYDYLVIGGGSGGLASAR--RAAELGARAAVV-ESHKLGGTCVNVGCVPKKVM
         60        70        80          90        100       110   

     180           190        200       210       220          230 
pF1KE6 W----FSDDPNVTKTLRFKQWNGK-ERSIYFQPPSFYVSAQDLPHIEN---GGVAVLTGK
       :     :.  .      : . .:: .  .  .  . :::  .  . .:   . . .. :.
NP_000 WNTAVHSEFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGH
           120       130       140       150       160       170   

             240       250       260       270       280       290 
pF1KE6 KVVQLDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFR
        .   : . . .... :.. :  . :::::: : .    .  :: .   .  :     :.
NP_000 AAFTSDPKPT-IEVS-GKKYTAPHILIATGGMPSTPHESQIPGASLGITSDGF-----FQ
           180         190       200       210       220           

             300       310       320       330       340       350 
pF1KE6 SLEKISREVKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLSNW
         :  .: :    :.:.:... :.:  :.    :::... .:. .. .. . .  ..:. 
NP_000 LEELPGRSV----IVGAGYIAVEMAGILS----ALGSKT-SLMIRHDKVLRSFDSMISTN
        230           240       250            260       270       

             360       370       380           390            400  
pF1KE6 TMEKVRREGVKVMPNAIVQSVGVSSGKLLIKLKD---GR-KVET-----DHIVAAVGLEP
         :...  ::.:.  . :. :  . . : ...     ::  : :     : .. :.:  :
NP_000 CTEELENAGVEVLKFSQVKEVKKTLSGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVP
       280       290       300       310       320       330       

            410       420       430         440       450       460
pF1KE6 NVELAKTGGLEIDSDFGGFRVNAELQARS--NIWVAGDAACFYDIKLGRRRVEHHDHAVV
       :..  . . : :..:  :  .  :.:  .  .:...::. :                   
NP_000 NTKDLSLNKLGIQTDDKGHIIVDEFQNTNVKGIYAVGDV-CGKALLTPVAIAAGRKLAHR
       340       350       360       370        380       390      

              470       480       490       500       510       520
pF1KE6 SGRLAGENMTGAAKPYWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSA
                                                                   
NP_000 LFEYKEDSKLDYNNIPTVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTK
        400       410       420       430       440       450      




613 residues in 1 query   sequences
64704883 residues in 91410 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Jul 24 16:38:45 2018 done: Tue Jul 24 16:38:46 2018
 Total Scan time:  5.080 Total Display time:  0.100

Function used was FASTA [36.3.4 Apr, 2011]
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