Result of FASTA (ccds) for pF1KE2025
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE2025, 608 aa
  1>>>pF1KE2025     608 - 608 aa - 608 aa
Library: human.CCDS.faa
  18921897 residues in 33420 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.4514+/-0.000896; mu= 14.8298+/- 0.054
 mean_var=98.4197+/-20.184, 0's: 0 Z-trim(108.7): 34  B-trim: 4 in 2/51
 Lambda= 0.129281
 statistics sampled from 10474 (10498) to 10474 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.314), width:  16
 Scan time:  1.640

The best scores are:                                      opt bits E(33420)
CCDS12250.1 CARM1 gene_id:10498|Hs109|chr19        ( 608) 4039 763.8       0
CCDS58200.1 PRMT8 gene_id:56341|Hs109|chr12        ( 385)  648 131.3 2.4e-30
CCDS8521.2 PRMT8 gene_id:56341|Hs109|chr12         ( 394)  648 131.3 2.4e-30
CCDS41360.2 PRMT6 gene_id:55170|Hs109|chr1         ( 375)  647 131.1 2.7e-30
CCDS42592.1 PRMT1 gene_id:3276|Hs109|chr19         ( 353)  641 129.9 5.5e-30
CCDS46145.1 PRMT1 gene_id:3276|Hs109|chr19         ( 371)  641 130.0 5.7e-30
CCDS44554.1 PRMT3 gene_id:10196|Hs109|chr11        ( 469)  642 130.2 6.1e-30
CCDS7853.1 PRMT3 gene_id:10196|Hs109|chr11         ( 531)  642 130.2 6.8e-30
CCDS13737.1 PRMT2 gene_id:3275|Hs109|chr21         ( 433)  625 127.0 5.1e-29
CCDS68230.1 PRMT2 gene_id:3275|Hs109|chr21         ( 289)  461 96.3 5.9e-20
CCDS74425.1 PRMT1 gene_id:3276|Hs109|chr19         ( 285)  419 88.5 1.3e-17
CCDS56220.1 PRMT2 gene_id:3275|Hs109|chr21         ( 331)  368 79.0 1.1e-14
CCDS68231.1 PRMT2 gene_id:3275|Hs109|chr21         ( 301)  367 78.8 1.2e-14
CCDS74806.1 PRMT2 gene_id:3275|Hs109|chr21         ( 228)  361 77.6   2e-14
CCDS56219.1 PRMT2 gene_id:3275|Hs109|chr21         ( 284)  362 77.9 2.1e-14


>>CCDS12250.1 CARM1 gene_id:10498|Hs109|chr19             (608 aa)
 initn: 4039 init1: 4039 opt: 4039  Z-score: 4073.7  bits: 763.8 E(33420):    0
Smith-Waterman score: 4039; 100.0% identity (100.0% similar) in 608 aa overlap (1-608:1-608)

               10        20        30        40        50        60
pF1KE2 MAAAAAAVGPGAGGAGSAVPGGAGPCATVSVFPGARLLTIGDANGEIQRHAEQQALRLEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 MAAAAAAVGPGAGGAGSAVPGGAGPCATVSVFPGARLLTIGDANGEIQRHAEQQALRLEV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 RAGPDSAGIALYSHEDVCVFKCSVSRETECSRVGKQSFIITLGCNSVLIQFATPNDFCSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 RAGPDSAGIALYSHEDVCVFKCSVSRETECSRVGKQSFIITLGCNSVLIQFATPNDFCSF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 YNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 YNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 TDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 TDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 KVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 KVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 QLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 QLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE2 EAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 EAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRC
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE2 LFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 LFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE2 PSPPPGSHYTSPSENMWNTGSTYNLSSGMAVAGMPTAYDLSSVIASGSSVGHNNLIPLAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 PSPPPGSHYTSPSENMWNTGSTYNLSSGMAVAGMPTAYDLSSVIASGSSVGHNNLIPLAN
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE2 TGIVNHTHSRMGSIMSTGIVQGSSGAQGSGGGSTSAHYAVNSQFTMGGPAISMASPMSIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 TGIVNHTHSRMGSIMSTGIVQGSSGAQGSGGGSTSAHYAVNSQFTMGGPAISMASPMSIP
              550       560       570       580       590       600

               
pF1KE2 TNTMHYGS
       ::::::::
CCDS12 TNTMHYGS
               

>>CCDS58200.1 PRMT8 gene_id:56341|Hs109|chr12             (385 aa)
 initn: 570 init1: 328 opt: 648  Z-score: 658.5  bits: 131.3 E(33420): 2.4e-30
Smith-Waterman score: 648; 33.5% identity (65.9% similar) in 352 aa overlap (112-460:31-371)

              90       100       110       120       130       140 
pF1KE2 CSVSRETECSRVGKQSFIITLGCNSVLIQFATPNDFCSFYNILKTCRGHTLERSVFSERT
                                     : : .     .   .: :.    .... . 
CCDS58 MESLASDGFKLKEVSSVNSPPSQPPQPVVPAKPVQCVHHVSTQPSCPGRGKMSKLLNPE-
               10        20        30        40        50          

             150       160       170       180       190       200 
pF1KE2 EESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFF
       : .:   ::. :.... ...:..: ::: ::. .. .:.  ::::.::::: :.::::.:
CCDS58 EMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMF
      60        70        80        90       100       110         

             210       220       230       240        250       260
pF1KE2 AAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLP-EQVDIIISEPMG
       ::.:::.:....: :......: ..:.:.: . :... :::::: :: :.::::::: ::
CCDS58 AAKAGAKKVFGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVEKVDIIISEWMG
     120       130       140       150       160       170         

              270        280       290       300       310         
pF1KE2 YMLFNERMLESYLHAK-KYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFH
       : :: : ::.. . :. :.:::.: :::  . .... . :.:  ...: : ..:   . .
CCDS58 YCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQ--YKDF-KIHWW--ENVY
     180       190       200       210       220          230      

     320       330       340        350       360       370        
pF1KE2 GVDLSALRGAAVDEYFRQPVVDTFDIR-ILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHM
       : :.. .: .:. :    :.::  : . ..    .   :..  .:  .:  .   : ...
CCDS58 GFDMTCIRDVAMKE----PLVDIVDPKQVVTNACLIKEVDIYTVKTEELS-FTSAFCLQI
          240           250       260       270       280          

      380       390       400       410       420       430        
pF1KE2 LHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTC
        ..  ::.:. .:.. :      . .::::  : ::: :.   ... : .. :. . :: 
CCDS58 QRNDYVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTI
     290       300       310       320       330       340         

      440       450       460       470       480       490        
pF1KE2 LLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTSPSENMWN
        .  : ..  :.......:  :                                      
CCDS58 SMKPNAKNVRDLDFTVDLDFKGQLCETSVSNDYKMR                        
     350       360       370       380                             

>>CCDS8521.2 PRMT8 gene_id:56341|Hs109|chr12              (394 aa)
 initn: 570 init1: 328 opt: 648  Z-score: 658.4  bits: 131.3 E(33420): 2.4e-30
Smith-Waterman score: 648; 33.5% identity (65.9% similar) in 352 aa overlap (112-460:40-380)

              90       100       110       120       130       140 
pF1KE2 CSVSRETECSRVGKQSFIITLGCNSVLIQFATPNDFCSFYNILKTCRGHTLERSVFSERT
                                     : : .     .   .: :.    .... . 
CCDS85 LLLRRKMAENAAESTEVNSPPSQPPQPVVPAKPVQCVHHVSTQPSCPGRGKMSKLLNPE-
      10        20        30        40        50        60         

             150       160       170       180       190       200 
pF1KE2 EESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFF
       : .:   ::. :.... ...:..: ::: ::. .. .:.  ::::.::::: :.::::.:
CCDS85 EMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMF
       70        80        90       100       110       120        

             210       220       230       240        250       260
pF1KE2 AAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLP-EQVDIIISEPMG
       ::.:::.:....: :......: ..:.:.: . :... :::::: :: :.::::::: ::
CCDS85 AAKAGAKKVFGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVEKVDIIISEWMG
      130       140       150       160       170       180        

              270        280       290       300       310         
pF1KE2 YMLFNERMLESYLHAK-KYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFH
       : :: : ::.. . :. :.:::.: :::  . .... . :.:  ...: : ..:   . .
CCDS85 YCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQ--YKDF-KIHWW--ENVY
      190       200       210       220       230            240   

     320       330       340        350       360       370        
pF1KE2 GVDLSALRGAAVDEYFRQPVVDTFDIR-ILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHM
       : :.. .: .:. :    :.::  : . ..    .   :..  .:  .:  .   : ...
CCDS85 GFDMTCIRDVAMKE----PLVDIVDPKQVVTNACLIKEVDIYTVKTEELS-FTSAFCLQI
           250           260       270       280        290        

      380       390       400       410       420       430        
pF1KE2 LHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTC
        ..  ::.:. .:.. :      . .::::  : ::: :.   ... : .. :. . :: 
CCDS85 QRNDYVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTI
      300       310       320       330       340       350        

      440       450       460       470       480       490        
pF1KE2 LLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTSPSENMWN
        .  : ..  :.......:  :                                      
CCDS85 SMKPNAKNVRDLDFTVDLDFKGQLCETSVSNDYKMR                        
      360       370       380       390                            

>>CCDS41360.2 PRMT6 gene_id:55170|Hs109|chr1              (375 aa)
 initn: 558 init1: 436 opt: 647  Z-score: 657.7  bits: 131.1 E(33420): 2.7e-30
Smith-Waterman score: 647; 35.8% identity (65.6% similar) in 352 aa overlap (128-469:29-371)

       100       110       120       130       140       150       
pF1KE2 FIITLGCNSVLIQFATPNDFCSFYNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLS
                                     :  .:::    .::..     :.. :. .:
CCDS41   MSQPKKRKLESGGGGEGGEGTEEEDGAEREAALER---PRRTKRERDQLYYECYSDVS
                 10        20        30           40        50     

       160       170       180       190       200       210       
pF1KE2 QQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEAST
        ...:. : ::: .:. .::.: . .. : ::::: :.::::.: ::::::..::::::.
CCDS41 VHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASA
          60        70        80        90       100       110     

       220       230       240       250       260       270       
pF1KE2 MAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAK-
       . :.:. .:. :.: ::. :.:: :: : :::::: :.:: ::: :..: :: : :::. 
CCDS41 IWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHART
         120       130       140       150       160       170     

        280       290       300       310        320       330     
pF1KE2 KYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFH-GVDLSALRGAAVDEYF
       :.:: .: ..:. ... .::..:..:      . .:: : . : :::.: :.: :.   .
CCDS41 KWLKEGGLLLPASAELFIAPISDQMLEW----RLGFWSQVKQHYGVDMSCLEGFATRCLM
         180       190       200           210       220       230 

           340       350       360       370           380         
pF1KE2 --RQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIP----FKFHMLHSGLVHGLAF
          . ::. .. . ..:.  ... ..  .. :  ...:      :.     :. .::.:.
CCDS41 GHSEIVVQGLSGEDVLARPQRFA-QLELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFAI
             240       250        260       270       280       290

     390         400       410       420       430       440       
pF1KE2 WFDVAFIG--SIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQS
       ::.:.: :  :   . :::.: .: ::: :.   .. :. ..    .::   :. .. . 
CCDS41 WFQVTFPGGESEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLLPSRDNP
              300       310       320       330       340       350

       450       460       470       480       490       500       
pF1KE2 YDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTSPSENMWNTGSTYNLSS
         . .. .  ..:..  .  :.                                      
CCDS41 RRLRVLLRY-KVGDQEEKTKDFAMED                                  
               360       370                                       

>>CCDS42592.1 PRMT1 gene_id:3276|Hs109|chr19              (353 aa)
 initn: 518 init1: 320 opt: 641  Z-score: 652.1  bits: 129.9 E(33420): 5.5e-30
Smith-Waterman score: 641; 35.9% identity (68.8% similar) in 320 aa overlap (144-460:30-339)

           120       130       140       150       160       170   
pF1KE2 PNDFCSFYNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQ
                                     .:   ::. :.... ...:..: ::: ::.
CCDS42  MAAAEAANCIMEVSCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYR
                10        20        30        40        50         

           180       190       200       210       220       230   
pF1KE2 RAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTD
        ....:.  ::::.::::: :.::: .:::.:::::. ..: :.....:  .::.:.:  
CCDS42 NSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDH
      60        70        80        90       100       110         

           240        250       260       270        280       290 
pF1KE2 RIVVIPGKVEEVSLP-EQVDIIISEPMGYMLFNERMLESYLHAK-KYLKPSGNMFPTIGD
        ...: :::::: :: :.::::::: ::: :: : ::.. :.:. :.: :.: .::  . 
CCDS42 VVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLYARDKWLAPDGLIFPDRAT
     120       130       140       150       160       170         

             300       310       320       330       340       350 
pF1KE2 VHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAK
       .... . :.: : .   : ..:   . .: :.: .. .:.    ..:.::. : . :...
CCDS42 LYVTAIEDRQ-YKDY--KIHWW--ENVYGFDMSCIKDVAI----KEPLVDVVDPKQLVTN
     180        190           200       210           220       230

              360       370       380       390       400       410
pF1KE2 S-VKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTE
       . .   :..  .:  ::  .  :: ... ..  ::.:. .:.. :      . .::.:  
CCDS42 ACLIKEVDIYTVKVEDL-TFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPES
              240        250       260       270       280         

              420       430       440       450       460       470
pF1KE2 PLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLK
       : ::: :.   ... : .:.:. . ::  .  : ... :.... ..:  :          
CCDS42 PYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLDFKGQLCELSCSTD
     290       300       310       320       330       340         

              480       490       500       510       520       530
pF1KE2 NPFFRYTGTTPSPPPGSHYTSPSENMWNTGSTYNLSSGMAVAGMPTAYDLSSVIASGSSV
                                                                   
CCDS42 YRMR                                                        
     350                                                           

>>CCDS46145.1 PRMT1 gene_id:3276|Hs109|chr19              (371 aa)
 initn: 518 init1: 320 opt: 641  Z-score: 651.7  bits: 130.0 E(33420): 5.7e-30
Smith-Waterman score: 641; 35.9% identity (68.8% similar) in 320 aa overlap (144-460:48-357)

           120       130       140       150       160       170   
pF1KE2 PNDFCSFYNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQ
                                     .:   ::. :.... ...:..: ::: ::.
CCDS46 LANGMSLQPPLEEVSCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYR
        20        30        40        50        60        70       

           180       190       200       210       220       230   
pF1KE2 RAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTD
        ....:.  ::::.::::: :.::: .:::.:::::. ..: :.....:  .::.:.:  
CCDS46 NSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDH
        80        90       100       110       120       130       

           240        250       260       270        280       290 
pF1KE2 RIVVIPGKVEEVSLP-EQVDIIISEPMGYMLFNERMLESYLHAK-KYLKPSGNMFPTIGD
        ...: :::::: :: :.::::::: ::: :: : ::.. :.:. :.: :.: .::  . 
CCDS46 VVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLYARDKWLAPDGLIFPDRAT
       140       150       160       170       180       190       

             300       310       320       330       340       350 
pF1KE2 VHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAK
       .... . :.: : .   : ..:   . .: :.: .. .:.    ..:.::. : . :...
CCDS46 LYVTAIEDRQ-YKDY--KIHWW--ENVYGFDMSCIKDVAI----KEPLVDVVDPKQLVTN
       200        210           220       230           240        

              360       370       380       390       400       410
pF1KE2 S-VKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTE
       . .   :..  .:  ::  .  :: ... ..  ::.:. .:.. :      . .::.:  
CCDS46 ACLIKEVDIYTVKVEDL-TFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPES
      250       260        270       280       290       300       

              420       430       440       450       460       470
pF1KE2 PLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLK
       : ::: :.   ... : .:.:. . ::  .  : ... :.... ..:  :          
CCDS46 PYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLDFKGQLCELSCSTD
       310       320       330       340       350       360       

              480       490       500       510       520       530
pF1KE2 NPFFRYTGTTPSPPPGSHYTSPSENMWNTGSTYNLSSGMAVAGMPTAYDLSSVIASGSSV
                                                                   
CCDS46 YRMR                                                        
       370                                                         

>>CCDS44554.1 PRMT3 gene_id:10196|Hs109|chr11             (469 aa)
 initn: 595 init1: 328 opt: 642  Z-score: 651.2  bits: 130.2 E(33420): 6.1e-30
Smith-Waterman score: 642; 34.4% identity (67.0% similar) in 355 aa overlap (110-459:126-462)

      80        90       100       110       120       130         
pF1KE2 FKCSVSRETECSRVGKQSFIITLGCNSVLIQFATPNDFCSFYNILKTCRGHTLERSVFSE
                                     :::  .::    .. .:: . :   ::...
CCDS44 VVEKLKHMEARALSAEAALARAREDLQKMKQFA--QDFVMHTDV-RTCSSST---SVIAD
         100       110       120         130        140            

     140       150       160       170       180       190         
pF1KE2 RTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILS
         :. ..: ::. ::. . ...:..: .:: .:.  : ::   ::::.:::::::.::::
CCDS44 LQEDEDGV-YFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILS
     150        160       170       180       190       200        

     200       210       220       230       240        250        
pF1KE2 FFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLP-EQVDIIISEP
       .:::.:::.:. .:. : .  .:  ... :.: : :..: ::.::: :: :.::.:::: 
CCDS44 MFAAKAGAKKVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDVIISEW
      210       220       230       240       250       260        

      260       270        280       290       300       310       
pF1KE2 MGYMLFNERMLESYLHAK-KYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPS
       :::.:. : ::.: :.:: :::  .:...: :  . :.  .: . . .   .  ::   .
CCDS44 MGYFLLFESMLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHAD---RIAFW--DD
      270       280       290       300       310          320     

       320       330       340       350         360       370     
pF1KE2 FHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAK--SVKYTVNFLEAKEGDLHRIEIPFK
        .:  .: .. :.. :     ::...: . :...  ..:. ..   .. .::. .   : 
CCDS44 VYGFKMSCMKKAVIPE----AVVEVLDPKTLISEPCGIKH-IDCHTTSISDLE-FSSDFT
           330           340       350        360       370        

         380       390       400        410       420       430    
pF1KE2 FHMLHSGLVHGLAFWFDVAFIGSIMT-VWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTL
       ... ....  ..: .::. :  .  . : .::.:    ::: :.  :...:. .:::..:
CCDS44 LKITRTSMCTAIAGYFDIYFEKNCHNRVVFSTGPQSTKTHWKQTVFLLEKPFSVKAGEAL
       380       390       400       410       420       430       

          440       450       460       470       480       490    
pF1KE2 SGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTSPSE
       .:   .  ::..  .....  ....                                   
CCDS44 KGKVTVHKNKKDPRSLTVTLTLNNSTQTYGLQ                            
       440       450       460                                     

>>CCDS7853.1 PRMT3 gene_id:10196|Hs109|chr11              (531 aa)
 initn: 571 init1: 328 opt: 642  Z-score: 650.4  bits: 130.2 E(33420): 6.8e-30
Smith-Waterman score: 642; 34.4% identity (67.0% similar) in 355 aa overlap (110-459:188-524)

      80        90       100       110       120       130         
pF1KE2 FKCSVSRETECSRVGKQSFIITLGCNSVLIQFATPNDFCSFYNILKTCRGHTLERSVFSE
                                     :::  .::    .. .:: . :   ::...
CCDS78 VVEKLKHMEARALSAEAALARAREDLQKMKQFA--QDFVMHTDV-RTCSSST---SVIAD
       160       170       180       190          200          210 

     140       150       160       170       180       190         
pF1KE2 RTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILS
         :. ..: ::. ::. . ...:..: .:: .:.  : ::   ::::.:::::::.::::
CCDS78 LQEDEDGV-YFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILS
              220       230       240       250       260       270

     200       210       220       230       240        250        
pF1KE2 FFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLP-EQVDIIISEP
       .:::.:::.:. .:. : .  .:  ... :.: : :..: ::.::: :: :.::.:::: 
CCDS78 MFAAKAGAKKVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDVIISEW
              280       290       300       310       320       330

      260       270        280       290       300       310       
pF1KE2 MGYMLFNERMLESYLHAK-KYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPS
       :::.:. : ::.: :.:: :::  .:...: :  . :.  .: . . .   .  ::   .
CCDS78 MGYFLLFESMLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHAD---RIAFW--DD
              340       350       360       370          380       

       320       330       340       350         360       370     
pF1KE2 FHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAK--SVKYTVNFLEAKEGDLHRIEIPFK
        .:  .: .. :.. :     ::...: . :...  ..:. ..   .. .::. .   : 
CCDS78 VYGFKMSCMKKAVIPE----AVVEVLDPKTLISEPCGIKH-IDCHTTSISDLE-FSSDFT
         390       400           410       420        430          

         380       390       400        410       420       430    
pF1KE2 FHMLHSGLVHGLAFWFDVAFIGSIMT-VWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTL
       ... ....  ..: .::. :  .  . : .::.:    ::: :.  :...:. .:::..:
CCDS78 LKITRTSMCTAIAGYFDIYFEKNCHNRVVFSTGPQSTKTHWKQTVFLLEKPFSVKAGEAL
     440       450       460       470       480       490         

          440       450       460       470       480       490    
pF1KE2 SGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTSPSE
       .:   .  ::..  .....  ....                                   
CCDS78 KGKVTVHKNKKDPRSLTVTLTLNNSTQTYGLQ                            
     500       510       520       530                             

>>CCDS13737.1 PRMT2 gene_id:3275|Hs109|chr21              (433 aa)
 initn: 434 init1: 225 opt: 625  Z-score: 634.6  bits: 127.0 E(33420): 5.1e-29
Smith-Waterman score: 625; 37.3% identity (66.2% similar) in 314 aa overlap (148-452:101-407)

       120       130       140       150       160       170       
pF1KE2 CSFYNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAIL
                                     .::  :: :. . .:. :  ::  :. .::
CCDS13 ERAGCCGYIPANHVGKHVDEYDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVIL
               80        90       100       110       120       130

       180       190       200        210       220       230      
pF1KE2 QNHTDFKDKIVLDVGCGSGILSFFAAQ-AGARKIYAVEASTMAQHAEVLVKSNNLTDRIV
       ::. .. ::..::::::.::.:.: :. :  : .:::::: ::::.  :: .:...: :.
CCDS13 QNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIIT
              140       150       160       170       180       190

        240       250       260       270        280       290     
pF1KE2 VIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKK-YLKPSGNMFPTIGDVHLA
       :   :::.: :::.::...:: ::  :. : :.:: :.:.  .:: .: ..::.. .::.
CCDS13 VYQQKVEDVVLPEKVDVLVSEWMGTCLLFEFMIESILYARDAWLKEDGVIWPTMAALHLV
              200       210       220       230       240       250

         300       310       320       330       340       350     
pF1KE2 PFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKY
       : . .. :    .:. ::   . .  .::::.. :: :.: .:  . . ..     :   
CCDS13 PCSADKDYR---SKVLFW--DNAYEFNLSALKSLAVKEFFSKPKYNHI-LKPEDCLSEPC
                 260         270       280       290        300    

         360          370       380       390           400        
pF1KE2 TVNFLEAKE---GDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFI----GSIMTVWLSTAP
       :.  :. .    .::. ..  ..: . ..: .::.. ::.: :     :.   : :::.:
CCDS13 TILQLDMRTVQISDLETLRGELRFDIRKAGTLHGFTAWFSVHFQSLQEGQPPQV-LSTGP
          310       320       330       340       350        360   

      410       420       430       440       450       460        
pF1KE2 TEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLD
        .: ::: :.  ....:. ...::...:. .:  :      .:.                
CCDS13 FHPTTHWKQTLFMMDDPVPVHTGDVVTGSVVLQRNPVWRRHMSVALSWAVTSRQDPTSQK
           370       380       390       400       410       420   

      470       480       490       500       510       520        
pF1KE2 LKNPFFRYTGTTPSPPPGSHYTSPSENMWNTGSTYNLSSGMAVAGMPTAYDLSSVIASGS
                                                                   
CCDS13 VGEKVFPIWR                                                  
           430                                                     

>>CCDS68230.1 PRMT2 gene_id:3275|Hs109|chr21              (289 aa)
 initn: 430 init1: 206 opt: 461  Z-score: 471.9  bits: 96.3 E(33420): 5.9e-20
Smith-Waterman score: 461; 44.5% identity (71.4% similar) in 182 aa overlap (148-327:101-277)

       120       130       140       150       160       170       
pF1KE2 CSFYNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAIL
                                     .::  :: :. . .:. :  ::  :. .::
CCDS68 ERAGCCGYIPANHVGKHVDEYDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVIL
               80        90       100       110       120       130

       180       190       200        210       220       230      
pF1KE2 QNHTDFKDKIVLDVGCGSGILSFFAAQ-AGARKIYAVEASTMAQHAEVLVKSNNLTDRIV
       ::. .. ::..::::::.::.:.: :. :  : .:::::: ::::.  :: .:...: :.
CCDS68 QNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIIT
              140       150       160       170       180       190

        240       250       260       270        280       290     
pF1KE2 VIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKK-YLKPSGNMFPTIGDVHLA
       :   :::.: :::.::...:: ::  :. : :.:: :.:.  .:: .: ..::.. .::.
CCDS68 VYQQKVEDVVLPEKVDVLVSEWMGTCLLFEFMIESILYARDAWLKEDGVIWPTMAALHLV
              200       210       220       230       240       250

         300       310       320       330       340       350     
pF1KE2 PFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKY
       : . .. :    .:. ::   . .  .::::.                            
CCDS68 PCSADKDYR---SKVLFW--DNAYEFNLSALKLEKKSSPSGDDS                
                 260         270       280                         

         360       370       380       390       400       410     
pF1KE2 TVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHW




608 residues in 1 query   sequences
18921897 residues in 33420 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Jul 16 16:06:48 2019 done: Tue Jul 16 16:06:48 2019
 Total Scan time:  1.640 Total Display time:  0.080

Function used was FASTA [36.3.4 Apr, 2011]
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