Result of FASTA (omim) for pF1KE2393
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE2393, 498 aa
  1>>>pF1KE2393 498 - 498 aa - 498 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.6205+/-0.000374; mu= 11.5745+/- 0.023
 mean_var=94.4857+/-18.720, 0's: 0 Z-trim(114.9): 167  B-trim: 0 in 0/52
 Lambda= 0.131944
 statistics sampled from 24775 (24947) to 24775 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.656), E-opt: 0.2 (0.292), width:  16
 Scan time:  9.710

The best scores are:                                      opt bits E(85289)
NP_000741 (OMIM: 118509) neuronal acetylcholine re ( 498) 3350 648.2 1.6e-185
XP_011519489 (OMIM: 118509) PREDICTED: neuronal ac ( 495) 3222 623.8 3.4e-178
XP_011519488 (OMIM: 118509) PREDICTED: neuronal ac ( 495) 3222 623.8 3.4e-178
XP_016877375 (OMIM: 118509) PREDICTED: neuronal ac ( 468) 3150 610.1 4.3e-174
XP_016877374 (OMIM: 118509) PREDICTED: neuronal ac ( 468) 3150 610.1 4.3e-174
XP_016877377 (OMIM: 118509) PREDICTED: neuronal ac ( 462) 2994 580.4 3.7e-165
XP_016877376 (OMIM: 118509) PREDICTED: neuronal ac ( 463) 2993 580.2 4.3e-165
XP_016877378 (OMIM: 118509) PREDICTED: neuronal ac ( 449) 2988 579.3 8.1e-165
XP_011519493 (OMIM: 118509) PREDICTED: neuronal ac ( 424) 2888 560.2 4.1e-159
XP_011519492 (OMIM: 118509) PREDICTED: neuronal ac ( 424) 2888 560.2 4.1e-159
XP_011519494 (OMIM: 118509) PREDICTED: neuronal ac ( 316) 2135 416.8 4.5e-116
NP_000739 (OMIM: 118507,605375) neuronal acetylcho ( 502) 2080 406.4 9.5e-113
NP_004189 (OMIM: 606888) neuronal acetylcholine re ( 494) 1460 288.4 3.2e-77
XP_016855669 (OMIM: 118507,605375) PREDICTED: neur ( 332) 1368 270.8 4.2e-72
NP_001186208 (OMIM: 606888) neuronal acetylcholine ( 479) 1317 261.2 4.8e-69
NP_001160166 (OMIM: 118503,612052) neuronal acetyl ( 489) 1292 256.4 1.3e-67
NP_000734 (OMIM: 118503,612052) neuronal acetylcho ( 505) 1292 256.4 1.4e-67
NP_000735 (OMIM: 118504,188890,600513) neuronal ac ( 627) 1284 255.0 4.7e-67
NP_000733 (OMIM: 118502,610353) neuronal acetylcho ( 529) 1281 254.4 6.1e-67
XP_006716345 (OMIM: 118502,610353) PREDICTED: neur ( 529) 1281 254.4 6.1e-67
XP_011542690 (OMIM: 118502,610353) PREDICTED: neur ( 529) 1281 254.4 6.1e-67
XP_006720445 (OMIM: 118503,612052) PREDICTED: neur ( 438) 1207 240.2   9e-63
NP_001269384 (OMIM: 118502,610353) neuronal acetyl ( 514) 1201 239.1 2.3e-62
NP_000740 (OMIM: 118508) neuronal acetylcholine re ( 458) 1190 237.0 8.8e-62
XP_016883113 (OMIM: 118504,188890,600513) PREDICTE ( 546) 1159 231.1 6.1e-60
NP_000736 (OMIM: 118505,612052) neuronal acetylcho ( 468) 1151 229.6 1.5e-59
NP_000070 (OMIM: 100690,253290,601462,608930) acet ( 457) 1116 222.9 1.5e-57
XP_016858746 (OMIM: 100690,253290,601462,608930) P ( 464) 1093 218.5 3.2e-56
NP_000737 (OMIM: 118511,612001) neuronal acetylcho ( 502) 1052 210.8 7.7e-54
NP_001177384 (OMIM: 118511,612001) neuronal acetyl ( 531) 1052 210.8 8.1e-54
XP_011519478 (OMIM: 118511,612001) PREDICTED: neur ( 486)  970 195.1 3.7e-49
NP_060051 (OMIM: 605116) neuronal acetylcholine re ( 479)  964 194.0 8.1e-49
NP_001034612 (OMIM: 100690,253290,601462,608930) a ( 482)  964 194.0 8.2e-49
XP_016858745 (OMIM: 100690,253290,601462,608930) P ( 489)  964 194.0 8.3e-49
NP_065135 (OMIM: 606372) neuronal acetylcholine re ( 450)  953 191.9 3.3e-48
XP_011526826 (OMIM: 118504,188890,600513) PREDICTE ( 556)  931 187.7 7.2e-47
XP_005273454 (OMIM: 118502,610353) PREDICTED: neur ( 370)  919 185.4 2.5e-46
XP_016868492 (OMIM: 118502,610353) PREDICTED: neur ( 370)  919 185.4 2.5e-46
XP_011519480 (OMIM: 118511,612001) PREDICTED: neur ( 380)  876 177.2 7.3e-44
XP_011542692 (OMIM: 118508) PREDICTED: neuronal ac ( 329)  837 169.7 1.1e-41
NP_001243496 (OMIM: 118509) neuronal acetylcholine ( 231)  780 158.8 1.5e-38
NP_000738 (OMIM: 100710,616313,616314) acetylcholi ( 501)  777 158.4 4.4e-38
NP_001243586 (OMIM: 100720,253290,616321,616322,61 ( 502)  765 156.1 2.1e-37
XP_011519479 (OMIM: 118511,612001) PREDICTED: neur ( 401)  754 154.0 7.5e-37
XP_016877372 (OMIM: 118511,612001) PREDICTED: neur ( 440)  750 153.2 1.4e-36
XP_016877371 (OMIM: 118511,612001) PREDICTED: neur ( 441)  750 153.2 1.4e-36
NP_647536 (OMIM: 609756) CHRNA7-FAM7A fusion prote ( 412)  749 153.0 1.5e-36
XP_011520455 (OMIM: 609756) PREDICTED: CHRNA7-FAM7 ( 412)  749 153.0 1.5e-36
XP_016868493 (OMIM: 118502,610353) PREDICTED: neur ( 331)  741 151.5 3.5e-36
XP_011542691 (OMIM: 118502,610353) PREDICTED: neur ( 331)  741 151.5 3.5e-36


>>NP_000741 (OMIM: 118509) neuronal acetylcholine recept  (498 aa)
 initn: 3350 init1: 3350 opt: 3350  Z-score: 3451.7  bits: 648.2 E(85289): 1.6e-185
Smith-Waterman score: 3350; 100.0% identity (100.0% similar) in 498 aa overlap (1-498:1-498)

               10        20        30        40        50        60
pF1KE2 MRRAPSLVLFFLVALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MRRAPSLVLFFLVALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 SLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 ADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 IDMVLMTPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVDVTYDFIIKRKPLFYTINLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IDMVLMTPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVDVTYDFIIKRKPLFYTINLI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 IPCVLTTLLAILVFYLPSDCGEKMTLCISVLLALTFFLLLISKIVPPTSLDVPLIGKYLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IPCVLTTLLAILVFYLPSDCGEKMTLCISVLLALTFFLLLISKIVPPTSLDVPLIGKYLM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 FTMVLVTFSIVTSVCVLNVHHRSPSTHTMAPWVKRCFLHKLPTFLFMKRPGPDSSPARAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FTMVLVTFSIVTSVCVLNVHHRSPSTHTMAPWVKRCFLHKLPTFLFMKRPGPDSSPARAF
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE2 PPSKSCVTKPEATATSTSPSNFYGNSMYFVNPASAASKSPAGSTPVAIPRDFWLRSSGRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PPSKSCVTKPEATATSTSPSNFYGNSMYFVNPASAASKSPAGSTPVAIPRDFWLRSSGRF
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE2 RQDVQEALEGVSFIAQHMKNDDEDQSVVEDWKYVAMVVDRLFLWVFMFVCVLGTVGLFLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RQDVQEALEGVSFIAQHMKNDDEDQSVVEDWKYVAMVVDRLFLWVFMFVCVLGTVGLFLP
              430       440       450       460       470       480

              490        
pF1KE2 PLFQTHAASEGPYAAQRD
       ::::::::::::::::::
NP_000 PLFQTHAASEGPYAAQRD
              490        

>>XP_011519489 (OMIM: 118509) PREDICTED: neuronal acetyl  (495 aa)
 initn: 3222 init1: 3222 opt: 3222  Z-score: 3320.1  bits: 623.8 E(85289): 3.4e-178
Smith-Waterman score: 3222; 100.0% identity (100.0% similar) in 479 aa overlap (20-498:17-495)

               10        20        30        40        50        60
pF1KE2 MRRAPSLVLFFLVALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQL
                          :::::::::::::::::::::::::::::::::::::::::
XP_011    MGGSLLAPAPDHIVLWNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQL
                  10        20        30        40        50       

               70        80        90       100       110       120
pF1KE2 SLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNN
        60        70        80        90       100       110       

              130       140       150       160       170       180
pF1KE2 ADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTE
       120       130       140       150       160       170       

              190       200       210       220       230       240
pF1KE2 IDMVLMTPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVDVTYDFIIKRKPLFYTINLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDMVLMTPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVDVTYDFIIKRKPLFYTINLI
       180       190       200       210       220       230       

              250       260       270       280       290       300
pF1KE2 IPCVLTTLLAILVFYLPSDCGEKMTLCISVLLALTFFLLLISKIVPPTSLDVPLIGKYLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPCVLTTLLAILVFYLPSDCGEKMTLCISVLLALTFFLLLISKIVPPTSLDVPLIGKYLM
       240       250       260       270       280       290       

              310       320       330       340       350       360
pF1KE2 FTMVLVTFSIVTSVCVLNVHHRSPSTHTMAPWVKRCFLHKLPTFLFMKRPGPDSSPARAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTMVLVTFSIVTSVCVLNVHHRSPSTHTMAPWVKRCFLHKLPTFLFMKRPGPDSSPARAF
       300       310       320       330       340       350       

              370       380       390       400       410       420
pF1KE2 PPSKSCVTKPEATATSTSPSNFYGNSMYFVNPASAASKSPAGSTPVAIPRDFWLRSSGRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPSKSCVTKPEATATSTSPSNFYGNSMYFVNPASAASKSPAGSTPVAIPRDFWLRSSGRF
       360       370       380       390       400       410       

              430       440       450       460       470       480
pF1KE2 RQDVQEALEGVSFIAQHMKNDDEDQSVVEDWKYVAMVVDRLFLWVFMFVCVLGTVGLFLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQDVQEALEGVSFIAQHMKNDDEDQSVVEDWKYVAMVVDRLFLWVFMFVCVLGTVGLFLP
       420       430       440       450       460       470       

              490        
pF1KE2 PLFQTHAASEGPYAAQRD
       ::::::::::::::::::
XP_011 PLFQTHAASEGPYAAQRD
       480       490     

>>XP_011519488 (OMIM: 118509) PREDICTED: neuronal acetyl  (495 aa)
 initn: 3222 init1: 3222 opt: 3222  Z-score: 3320.1  bits: 623.8 E(85289): 3.4e-178
Smith-Waterman score: 3222; 100.0% identity (100.0% similar) in 479 aa overlap (20-498:17-495)

               10        20        30        40        50        60
pF1KE2 MRRAPSLVLFFLVALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQL
                          :::::::::::::::::::::::::::::::::::::::::
XP_011    MGGSLLAPAPDHIVLWNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQL
                  10        20        30        40        50       

               70        80        90       100       110       120
pF1KE2 SLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNN
        60        70        80        90       100       110       

              130       140       150       160       170       180
pF1KE2 ADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTE
       120       130       140       150       160       170       

              190       200       210       220       230       240
pF1KE2 IDMVLMTPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVDVTYDFIIKRKPLFYTINLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDMVLMTPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVDVTYDFIIKRKPLFYTINLI
       180       190       200       210       220       230       

              250       260       270       280       290       300
pF1KE2 IPCVLTTLLAILVFYLPSDCGEKMTLCISVLLALTFFLLLISKIVPPTSLDVPLIGKYLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPCVLTTLLAILVFYLPSDCGEKMTLCISVLLALTFFLLLISKIVPPTSLDVPLIGKYLM
       240       250       260       270       280       290       

              310       320       330       340       350       360
pF1KE2 FTMVLVTFSIVTSVCVLNVHHRSPSTHTMAPWVKRCFLHKLPTFLFMKRPGPDSSPARAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTMVLVTFSIVTSVCVLNVHHRSPSTHTMAPWVKRCFLHKLPTFLFMKRPGPDSSPARAF
       300       310       320       330       340       350       

              370       380       390       400       410       420
pF1KE2 PPSKSCVTKPEATATSTSPSNFYGNSMYFVNPASAASKSPAGSTPVAIPRDFWLRSSGRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPSKSCVTKPEATATSTSPSNFYGNSMYFVNPASAASKSPAGSTPVAIPRDFWLRSSGRF
       360       370       380       390       400       410       

              430       440       450       460       470       480
pF1KE2 RQDVQEALEGVSFIAQHMKNDDEDQSVVEDWKYVAMVVDRLFLWVFMFVCVLGTVGLFLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQDVQEALEGVSFIAQHMKNDDEDQSVVEDWKYVAMVVDRLFLWVFMFVCVLGTVGLFLP
       420       430       440       450       460       470       

              490        
pF1KE2 PLFQTHAASEGPYAAQRD
       ::::::::::::::::::
XP_011 PLFQTHAASEGPYAAQRD
       480       490     

>>XP_016877375 (OMIM: 118509) PREDICTED: neuronal acetyl  (468 aa)
 initn: 3150 init1: 3150 opt: 3150  Z-score: 3246.4  bits: 610.1 E(85289): 4.3e-174
Smith-Waterman score: 3150; 100.0% identity (100.0% similar) in 468 aa overlap (31-498:1-468)

               10        20        30        40        50        60
pF1KE2 MRRAPSLVLFFLVALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQL
                                     ::::::::::::::::::::::::::::::
XP_016                               MDDLLNKTRYNNLIRPATSSSQLISIKLQL
                                             10        20        30

               70        80        90       100       110       120
pF1KE2 SLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNN
               40        50        60        70        80        90

              130       140       150       160       170       180
pF1KE2 ADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTE
              100       110       120       130       140       150

              190       200       210       220       230       240
pF1KE2 IDMVLMTPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVDVTYDFIIKRKPLFYTINLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDMVLMTPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVDVTYDFIIKRKPLFYTINLI
              160       170       180       190       200       210

              250       260       270       280       290       300
pF1KE2 IPCVLTTLLAILVFYLPSDCGEKMTLCISVLLALTFFLLLISKIVPPTSLDVPLIGKYLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPCVLTTLLAILVFYLPSDCGEKMTLCISVLLALTFFLLLISKIVPPTSLDVPLIGKYLM
              220       230       240       250       260       270

              310       320       330       340       350       360
pF1KE2 FTMVLVTFSIVTSVCVLNVHHRSPSTHTMAPWVKRCFLHKLPTFLFMKRPGPDSSPARAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTMVLVTFSIVTSVCVLNVHHRSPSTHTMAPWVKRCFLHKLPTFLFMKRPGPDSSPARAF
              280       290       300       310       320       330

              370       380       390       400       410       420
pF1KE2 PPSKSCVTKPEATATSTSPSNFYGNSMYFVNPASAASKSPAGSTPVAIPRDFWLRSSGRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPSKSCVTKPEATATSTSPSNFYGNSMYFVNPASAASKSPAGSTPVAIPRDFWLRSSGRF
              340       350       360       370       380       390

              430       440       450       460       470       480
pF1KE2 RQDVQEALEGVSFIAQHMKNDDEDQSVVEDWKYVAMVVDRLFLWVFMFVCVLGTVGLFLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQDVQEALEGVSFIAQHMKNDDEDQSVVEDWKYVAMVVDRLFLWVFMFVCVLGTVGLFLP
              400       410       420       430       440       450

              490        
pF1KE2 PLFQTHAASEGPYAAQRD
       ::::::::::::::::::
XP_016 PLFQTHAASEGPYAAQRD
              460        

>>XP_016877374 (OMIM: 118509) PREDICTED: neuronal acetyl  (468 aa)
 initn: 3150 init1: 3150 opt: 3150  Z-score: 3246.4  bits: 610.1 E(85289): 4.3e-174
Smith-Waterman score: 3150; 100.0% identity (100.0% similar) in 468 aa overlap (31-498:1-468)

               10        20        30        40        50        60
pF1KE2 MRRAPSLVLFFLVALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQL
                                     ::::::::::::::::::::::::::::::
XP_016                               MDDLLNKTRYNNLIRPATSSSQLISIKLQL
                                             10        20        30

               70        80        90       100       110       120
pF1KE2 SLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNN
               40        50        60        70        80        90

              130       140       150       160       170       180
pF1KE2 ADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTE
              100       110       120       130       140       150

              190       200       210       220       230       240
pF1KE2 IDMVLMTPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVDVTYDFIIKRKPLFYTINLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDMVLMTPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVDVTYDFIIKRKPLFYTINLI
              160       170       180       190       200       210

              250       260       270       280       290       300
pF1KE2 IPCVLTTLLAILVFYLPSDCGEKMTLCISVLLALTFFLLLISKIVPPTSLDVPLIGKYLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPCVLTTLLAILVFYLPSDCGEKMTLCISVLLALTFFLLLISKIVPPTSLDVPLIGKYLM
              220       230       240       250       260       270

              310       320       330       340       350       360
pF1KE2 FTMVLVTFSIVTSVCVLNVHHRSPSTHTMAPWVKRCFLHKLPTFLFMKRPGPDSSPARAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTMVLVTFSIVTSVCVLNVHHRSPSTHTMAPWVKRCFLHKLPTFLFMKRPGPDSSPARAF
              280       290       300       310       320       330

              370       380       390       400       410       420
pF1KE2 PPSKSCVTKPEATATSTSPSNFYGNSMYFVNPASAASKSPAGSTPVAIPRDFWLRSSGRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPSKSCVTKPEATATSTSPSNFYGNSMYFVNPASAASKSPAGSTPVAIPRDFWLRSSGRF
              340       350       360       370       380       390

              430       440       450       460       470       480
pF1KE2 RQDVQEALEGVSFIAQHMKNDDEDQSVVEDWKYVAMVVDRLFLWVFMFVCVLGTVGLFLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQDVQEALEGVSFIAQHMKNDDEDQSVVEDWKYVAMVVDRLFLWVFMFVCVLGTVGLFLP
              400       410       420       430       440       450

              490        
pF1KE2 PLFQTHAASEGPYAAQRD
       ::::::::::::::::::
XP_016 PLFQTHAASEGPYAAQRD
              460        

>>XP_016877377 (OMIM: 118509) PREDICTED: neuronal acetyl  (462 aa)
 initn: 2994 init1: 2994 opt: 2994  Z-score: 3086.0  bits: 580.4 E(85289): 3.7e-165
Smith-Waterman score: 2994; 99.8% identity (100.0% similar) in 448 aa overlap (1-448:1-448)

               10        20        30        40        50        60
pF1KE2 MRRAPSLVLFFLVALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRRAPSLVLFFLVALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 SLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 ADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 IDMVLMTPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVDVTYDFIIKRKPLFYTINLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDMVLMTPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVDVTYDFIIKRKPLFYTINLI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 IPCVLTTLLAILVFYLPSDCGEKMTLCISVLLALTFFLLLISKIVPPTSLDVPLIGKYLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPCVLTTLLAILVFYLPSDCGEKMTLCISVLLALTFFLLLISKIVPPTSLDVPLIGKYLM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 FTMVLVTFSIVTSVCVLNVHHRSPSTHTMAPWVKRCFLHKLPTFLFMKRPGPDSSPARAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTMVLVTFSIVTSVCVLNVHHRSPSTHTMAPWVKRCFLHKLPTFLFMKRPGPDSSPARAF
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE2 PPSKSCVTKPEATATSTSPSNFYGNSMYFVNPASAASKSPAGSTPVAIPRDFWLRSSGRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPSKSCVTKPEATATSTSPSNFYGNSMYFVNPASAASKSPAGSTPVAIPRDFWLRSSGRF
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE2 RQDVQEALEGVSFIAQHMKNDDEDQSVVEDWKYVAMVVDRLFLWVFMFVCVLGTVGLFLP
       :::::::::::::::::::::::::::.                                
XP_016 RQDVQEALEGVSFIAQHMKNDDEDQSVMPACQNKHPWCWRKP                  
              430       440       450       460                    

>>XP_016877376 (OMIM: 118509) PREDICTED: neuronal acetyl  (463 aa)
 initn: 2993 init1: 2993 opt: 2993  Z-score: 3085.0  bits: 580.2 E(85289): 4.3e-165
Smith-Waterman score: 2993; 100.0% identity (100.0% similar) in 447 aa overlap (1-447:1-447)

               10        20        30        40        50        60
pF1KE2 MRRAPSLVLFFLVALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRRAPSLVLFFLVALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 SLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 ADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 IDMVLMTPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVDVTYDFIIKRKPLFYTINLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDMVLMTPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVDVTYDFIIKRKPLFYTINLI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 IPCVLTTLLAILVFYLPSDCGEKMTLCISVLLALTFFLLLISKIVPPTSLDVPLIGKYLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPCVLTTLLAILVFYLPSDCGEKMTLCISVLLALTFFLLLISKIVPPTSLDVPLIGKYLM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 FTMVLVTFSIVTSVCVLNVHHRSPSTHTMAPWVKRCFLHKLPTFLFMKRPGPDSSPARAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTMVLVTFSIVTSVCVLNVHHRSPSTHTMAPWVKRCFLHKLPTFLFMKRPGPDSSPARAF
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE2 PPSKSCVTKPEATATSTSPSNFYGNSMYFVNPASAASKSPAGSTPVAIPRDFWLRSSGRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPSKSCVTKPEATATSTSPSNFYGNSMYFVNPASAASKSPAGSTPVAIPRDFWLRSSGRF
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE2 RQDVQEALEGVSFIAQHMKNDDEDQSVVEDWKYVAMVVDRLFLWVFMFVCVLGTVGLFLP
       :::::::::::::::::::::::::::                                 
XP_016 RQDVQEALEGVSFIAQHMKNDDEDQSVSQKQTPRWGLGCRWFT                 
              430       440       450       460                    

>>XP_016877378 (OMIM: 118509) PREDICTED: neuronal acetyl  (449 aa)
 initn: 2988 init1: 2988 opt: 2988  Z-score: 3080.0  bits: 579.3 E(85289): 8.1e-165
Smith-Waterman score: 2988; 100.0% identity (100.0% similar) in 446 aa overlap (1-446:1-446)

               10        20        30        40        50        60
pF1KE2 MRRAPSLVLFFLVALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRRAPSLVLFFLVALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 SLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 ADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 IDMVLMTPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVDVTYDFIIKRKPLFYTINLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDMVLMTPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVDVTYDFIIKRKPLFYTINLI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 IPCVLTTLLAILVFYLPSDCGEKMTLCISVLLALTFFLLLISKIVPPTSLDVPLIGKYLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPCVLTTLLAILVFYLPSDCGEKMTLCISVLLALTFFLLLISKIVPPTSLDVPLIGKYLM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 FTMVLVTFSIVTSVCVLNVHHRSPSTHTMAPWVKRCFLHKLPTFLFMKRPGPDSSPARAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTMVLVTFSIVTSVCVLNVHHRSPSTHTMAPWVKRCFLHKLPTFLFMKRPGPDSSPARAF
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE2 PPSKSCVTKPEATATSTSPSNFYGNSMYFVNPASAASKSPAGSTPVAIPRDFWLRSSGRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPSKSCVTKPEATATSTSPSNFYGNSMYFVNPASAASKSPAGSTPVAIPRDFWLRSSGRF
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE2 RQDVQEALEGVSFIAQHMKNDDEDQSVVEDWKYVAMVVDRLFLWVFMFVCVLGTVGLFLP
       ::::::::::::::::::::::::::                                  
XP_016 RQDVQEALEGVSFIAQHMKNDDEDQSSLC                               
              430       440                                        

>>XP_011519493 (OMIM: 118509) PREDICTED: neuronal acetyl  (424 aa)
 initn: 2888 init1: 2888 opt: 2888  Z-score: 2977.6  bits: 560.2 E(85289): 4.1e-159
Smith-Waterman score: 2888; 100.0% identity (100.0% similar) in 424 aa overlap (75-498:1-424)

           50        60        70        80        90       100    
pF1KE2 RPATSSSQLISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILR
                                     ::::::::::::::::::::::::::::::
XP_011                               MTTNVWLKQEWTDYRLTWNSSRYEGVNILR
                                             10        20        30

          110       120       130       140       150       160    
pF1KE2 IPAKRIWLPDIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPAKRIWLPDIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQ
               40        50        60        70        80        90

          170       180       190       200       210       220    
pF1KE2 QNCTLKFRSWTYDHTEIDMVLMTPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVDVTY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNCTLKFRSWTYDHTEIDMVLMTPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVDVTY
              100       110       120       130       140       150

          230       240       250       260       270       280    
pF1KE2 DFIIKRKPLFYTINLIIPCVLTTLLAILVFYLPSDCGEKMTLCISVLLALTFFLLLISKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFIIKRKPLFYTINLIIPCVLTTLLAILVFYLPSDCGEKMTLCISVLLALTFFLLLISKI
              160       170       180       190       200       210

          290       300       310       320       330       340    
pF1KE2 VPPTSLDVPLIGKYLMFTMVLVTFSIVTSVCVLNVHHRSPSTHTMAPWVKRCFLHKLPTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPPTSLDVPLIGKYLMFTMVLVTFSIVTSVCVLNVHHRSPSTHTMAPWVKRCFLHKLPTF
              220       230       240       250       260       270

          350       360       370       380       390       400    
pF1KE2 LFMKRPGPDSSPARAFPPSKSCVTKPEATATSTSPSNFYGNSMYFVNPASAASKSPAGST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFMKRPGPDSSPARAFPPSKSCVTKPEATATSTSPSNFYGNSMYFVNPASAASKSPAGST
              280       290       300       310       320       330

          410       420       430       440       450       460    
pF1KE2 PVAIPRDFWLRSSGRFRQDVQEALEGVSFIAQHMKNDDEDQSVVEDWKYVAMVVDRLFLW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVAIPRDFWLRSSGRFRQDVQEALEGVSFIAQHMKNDDEDQSVVEDWKYVAMVVDRLFLW
              340       350       360       370       380       390

          470       480       490        
pF1KE2 VFMFVCVLGTVGLFLPPLFQTHAASEGPYAAQRD
       ::::::::::::::::::::::::::::::::::
XP_011 VFMFVCVLGTVGLFLPPLFQTHAASEGPYAAQRD
              400       410       420    

>>XP_011519492 (OMIM: 118509) PREDICTED: neuronal acetyl  (424 aa)
 initn: 2888 init1: 2888 opt: 2888  Z-score: 2977.6  bits: 560.2 E(85289): 4.1e-159
Smith-Waterman score: 2888; 100.0% identity (100.0% similar) in 424 aa overlap (75-498:1-424)

           50        60        70        80        90       100    
pF1KE2 RPATSSSQLISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILR
                                     ::::::::::::::::::::::::::::::
XP_011                               MTTNVWLKQEWTDYRLTWNSSRYEGVNILR
                                             10        20        30

          110       120       130       140       150       160    
pF1KE2 IPAKRIWLPDIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPAKRIWLPDIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQ
               40        50        60        70        80        90

          170       180       190       200       210       220    
pF1KE2 QNCTLKFRSWTYDHTEIDMVLMTPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVDVTY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNCTLKFRSWTYDHTEIDMVLMTPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVDVTY
              100       110       120       130       140       150

          230       240       250       260       270       280    
pF1KE2 DFIIKRKPLFYTINLIIPCVLTTLLAILVFYLPSDCGEKMTLCISVLLALTFFLLLISKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFIIKRKPLFYTINLIIPCVLTTLLAILVFYLPSDCGEKMTLCISVLLALTFFLLLISKI
              160       170       180       190       200       210

          290       300       310       320       330       340    
pF1KE2 VPPTSLDVPLIGKYLMFTMVLVTFSIVTSVCVLNVHHRSPSTHTMAPWVKRCFLHKLPTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPPTSLDVPLIGKYLMFTMVLVTFSIVTSVCVLNVHHRSPSTHTMAPWVKRCFLHKLPTF
              220       230       240       250       260       270

          350       360       370       380       390       400    
pF1KE2 LFMKRPGPDSSPARAFPPSKSCVTKPEATATSTSPSNFYGNSMYFVNPASAASKSPAGST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFMKRPGPDSSPARAFPPSKSCVTKPEATATSTSPSNFYGNSMYFVNPASAASKSPAGST
              280       290       300       310       320       330

          410       420       430       440       450       460    
pF1KE2 PVAIPRDFWLRSSGRFRQDVQEALEGVSFIAQHMKNDDEDQSVVEDWKYVAMVVDRLFLW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVAIPRDFWLRSSGRFRQDVQEALEGVSFIAQHMKNDDEDQSVVEDWKYVAMVVDRLFLW
              340       350       360       370       380       390

          470       480       490        
pF1KE2 VFMFVCVLGTVGLFLPPLFQTHAASEGPYAAQRD
       ::::::::::::::::::::::::::::::::::
XP_011 VFMFVCVLGTVGLFLPPLFQTHAASEGPYAAQRD
              400       410       420    




498 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 09:29:00 2016 done: Sun Nov  6 09:29:01 2016
 Total Scan time:  9.710 Total Display time:  0.090

Function used was FASTA [36.3.4 Apr, 2011]
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