Result of FASTA (omim) for pF1KE2339
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE2339, 290 aa
  1>>>pF1KE2339 290 - 290 aa - 290 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.0041+/-0.000366; mu= 16.7332+/- 0.023
 mean_var=63.5557+/-12.869, 0's: 0 Z-trim(112.6): 56  B-trim: 0 in 0/58
 Lambda= 0.160878
 statistics sampled from 21488 (21544) to 21488 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.628), E-opt: 0.2 (0.253), width:  16
 Scan time:  6.140

The best scores are:                                      opt bits E(85289)
NP_004083 (OMIM: 602292,616277) enoyl-CoA hydratas ( 290) 1893 448.1 9.4e-126
NP_001689 (OMIM: 250950,600529) methylglutaconyl-C ( 339)  450 113.2   7e-25
XP_005252123 (OMIM: 250950,600529) PREDICTED: meth ( 349)  445 112.0 1.6e-24
XP_011517104 (OMIM: 250950,600529) PREDICTED: meth ( 230)  416 105.2 1.2e-22
XP_016870339 (OMIM: 250950,600529) PREDICTED: meth ( 230)  416 105.2 1.2e-22
NP_001957 (OMIM: 607037,615605) peroxisomal bifunc ( 723)  379 96.9 1.2e-19
XP_016870338 (OMIM: 250950,600529) PREDICTED: meth ( 323)  367 93.9 4.3e-19
NP_001293119 (OMIM: 250950,600529) methylglutacony ( 310)  365 93.4 5.7e-19
XP_006717213 (OMIM: 250950,600529) PREDICTED: meth ( 320)  365 93.5 5.8e-19
XP_005252124 (OMIM: 250950,600529) PREDICTED: meth ( 333)  362 92.8 9.8e-19
XP_005252126 (OMIM: 250950,600529) PREDICTED: meth ( 298)  344 88.6 1.6e-17
XP_016870340 (OMIM: 250950,600529) PREDICTED: meth ( 214)  333 85.9 7.3e-17
NP_932164 (OMIM: 250620,610690) 3-hydroxyisobutyry ( 338)  335 86.5 7.6e-17
NP_055177 (OMIM: 250620,610690) 3-hydroxyisobutyry ( 386)  335 86.5 8.5e-17
XP_011509255 (OMIM: 250620,610690) PREDICTED: 3-hy ( 386)  335 86.5 8.5e-17
NP_000173 (OMIM: 600890,609015,609016) trifunction ( 763)  333 86.3   2e-16
NP_733841 (OMIM: 400016,415000) testis-specific ch ( 540)  316 82.2 2.4e-15
NP_004816 (OMIM: 400018,415000) testis-specific ch ( 541)  312 81.3 4.5e-15
NP_001137443 (OMIM: 603778) chromodomain Y-like pr ( 412)  303 79.1 1.5e-14
NP_001137442 (OMIM: 603778) chromodomain Y-like pr ( 412)  303 79.1 1.5e-14
XP_011513299 (OMIM: 603778) PREDICTED: chromodomai ( 522)  303 79.2 1.9e-14
NP_004815 (OMIM: 603778) chromodomain Y-like prote ( 544)  303 79.2 1.9e-14
NP_004671 (OMIM: 400016,415000) testis-specific ch ( 554)  297 77.8 5.1e-14
XP_016881937 (OMIM: 600696) PREDICTED: delta(3,5)- ( 248)  269 71.1 2.4e-12
NP_001389 (OMIM: 600696) delta(3,5)-Delta(2,4)-die ( 328)  269 71.2   3e-12
NP_001002030 (OMIM: 612136) ethylmalonyl-CoA decar ( 301)  267 70.7 3.9e-12
XP_005267105 (OMIM: 612136) PREDICTED: ethylmalony ( 301)  267 70.7 3.9e-12
XP_005267104 (OMIM: 612136) PREDICTED: ethylmalony ( 301)  267 70.7 3.9e-12
NP_001132982 (OMIM: 612136) ethylmalonyl-CoA decar ( 307)  267 70.7   4e-12
NP_001159482 (OMIM: 608024) enoyl-CoA delta isomer ( 364)  250 66.8   7e-11
NP_006108 (OMIM: 608024) enoyl-CoA delta isomerase ( 364)  250 66.8   7e-11
NP_996667 (OMIM: 608024) enoyl-CoA delta isomerase ( 394)  250 66.8 7.5e-11
XP_011529814 (OMIM: 400016,415000) PREDICTED: test ( 470)  249 66.6   1e-10
XP_011510819 (OMIM: 607037,615605) PREDICTED: pero ( 627)  235 63.5 1.2e-09
NP_001159887 (OMIM: 607037,615605) peroxisomal bif ( 627)  235 63.5 1.2e-09
XP_005252129 (OMIM: 250950,600529) PREDICTED: meth ( 255)  222 60.2 4.8e-09
XP_016866545 (OMIM: 612136) PREDICTED: ethylmalony ( 226)  219 59.5   7e-09
NP_001099014 (OMIM: 612136) ethylmalonyl-CoA decar ( 226)  219 59.5   7e-09
XP_011517102 (OMIM: 250950,600529) PREDICTED: meth ( 265)  217 59.0 1.1e-08
NP_001910 (OMIM: 600305) enoyl-CoA delta isomerase ( 302)  206 56.5 7.2e-08
XP_011534244 (OMIM: 612136) PREDICTED: ethylmalony ( 189)  188 52.2 8.9e-07
NP_001171500 (OMIM: 600305) enoyl-CoA delta isomer ( 285)  150 43.5 0.00056
XP_016865659 (OMIM: 608024) PREDICTED: enoyl-CoA d ( 334)  150 43.6 0.00064
XP_006715020 (OMIM: 608024) PREDICTED: enoyl-CoA d ( 364)  150 43.6 0.00068


>>NP_004083 (OMIM: 602292,616277) enoyl-CoA hydratase, m  (290 aa)
 initn: 1893 init1: 1893 opt: 1893  Z-score: 2378.7  bits: 448.1 E(85289): 9.4e-126
Smith-Waterman score: 1893; 100.0% identity (100.0% similar) in 290 aa overlap (1-290:1-290)

               10        20        30        40        50        60
pF1KE2 MAALRVLLSCVRGPLRPPVRCPAWRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MAALRVLLSCVRGPLRPPVRCPAWRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 LCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 DHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 RAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMA
              190       200       210       220       230       240

              250       260       270       280       290
pF1KE2 KESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKANFKDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKANFKDQ
              250       260       270       280       290

>>NP_001689 (OMIM: 250950,600529) methylglutaconyl-CoA h  (339 aa)
 initn: 353 init1: 264 opt: 450  Z-score: 567.6  bits: 113.2 E(85289): 7e-25
Smith-Waterman score: 450; 32.2% identity (66.3% similar) in 255 aa overlap (43-290:85-339)

             20        30        40        50        60        70  
pF1KE2 GPLRPPVRCPAWRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQA
                                     .:  . .. .::  . :.:  .::  :..:
NP_001 VPAAGGPAPKRGYSSEMKTEDELRVRHLEEENRGIVVLGINRAYGKNSLSKNLIKMLSKA
           60        70        80        90       100       110    

             80        90        100       110         120         
pF1KE2 LKTFEEDPAVGAIVLTGG-DKAFAAGADIKEMQNLSFQDC--YSSKFLKHWDHLTQVKKP
       . ... :  : .:.. .     : ::::.::  ..: ..   . ::.    . ....  :
NP_001 VDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDIANLPVP
          120       130       140       150       160       170    

     130       140       150       160       170       180         
pF1KE2 VIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAM
       .:::..: :.::: :::. :::  :. .:...  :  .. :::.:::::: ::.: ::: 
NP_001 TIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAK
          180       190       200       210       220       230    

     190       200       210           220       230       240     
pF1KE2 EMVLTGDRISAQDAKQAGLVSKICPV----ETLVEEAIQCAEKIASNSKIVVAMAKESVN
       :.....  .....:: .::.:..       ..  ..:.. :...  .. ... .:: ..:
NP_001 ELIFSARVLDGKEAKAVGLISHVLEQNQEGDAAYRKALDLAREFLPQGPVAMRVAKLAIN
          240       250       260       270       280       290    

         250       260       270       280       290
pF1KE2 AAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKANFKDQ
        ..:. :. :  .:.  . .:. : :: ::. :: :::   .: .
NP_001 QGMEVDLVTGLAIEEACYAQTIPTKDRLEGLLAFKEKRPPRYKGE
          300       310       320       330         

>>XP_005252123 (OMIM: 250950,600529) PREDICTED: methylgl  (349 aa)
 initn: 353 init1: 264 opt: 445  Z-score: 561.2  bits: 112.0 E(85289): 1.6e-24
Smith-Waterman score: 445; 32.5% identity (66.7% similar) in 249 aa overlap (49-290:101-349)

       20        30        40        50        60        70        
pF1KE2 VRCPAWRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEE
                                     .. .::  . :.:  .::  :..:. ... 
XP_005 MKTEDELRVRHLEEENRDSSSMAADHYRIVVLGINRAYGKNSLSKNLIKMLSKAVDALKS
               80        90       100       110       120       130

       80        90        100       110         120       130     
pF1KE2 DPAVGAIVLTGG-DKAFAAGADIKEMQNLSFQDC--YSSKFLKHWDHLTQVKKPVIAAVN
       :  : .:.. .     : ::::.::  ..: ..   . ::.    . ....  :.:::..
XP_005 DKKVRTIIIRSEVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDIANLPVPTIAAID
              140       150       160       170       180       190

         140       150       160       170       180       190     
pF1KE2 GYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTG
       : :.::: :::. :::  :. .:...  :  .. :::.:::::: ::.: ::: :.....
XP_005 GLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSA
              200       210       220       230       240       250

         200       210           220       230       240       250 
pF1KE2 DRISAQDAKQAGLVSKICPV----ETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMT
         .....:: .::.:..       ..  ..:.. :...  .. ... .:: ..: ..:. 
XP_005 RVLDGKEAKAVGLISHVLEQNQEGDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVD
              260       270       280       290       300       310

             260       270       280       290
pF1KE2 LTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKANFKDQ
       :. :  .:.  . .:. : :: ::. :: :::   .: .
XP_005 LVTGLAIEEACYAQTIPTKDRLEGLLAFKEKRPPRYKGE
              320       330       340         

>>XP_011517104 (OMIM: 250950,600529) PREDICTED: methylgl  (230 aa)
 initn: 353 init1: 264 opt: 416  Z-score: 527.4  bits: 105.2 E(85289): 1.2e-22
Smith-Waterman score: 416; 32.8% identity (67.2% similar) in 229 aa overlap (69-290:2-230)

       40        50        60        70        80        90        
pF1KE2 EKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGG-DKAFAAG
                                     :..:. ... :  : .:.. .     : ::
XP_011                              MLSKAVDALKSDKKVRTIIIRSEVPGIFCAG
                                            10        20        30 

       100       110         120       130       140       150     
pF1KE2 ADIKEMQNLSFQDC--YSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAG
       ::.::  ..: ..   . ::.    . ....  :.:::..: :.::: :::. :::  :.
XP_011 ADLKERAKMSSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAA
              40        50        60        70        80        90 

         160       170       180       190       200       210     
pF1KE2 EKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPV
        .:...  :  .. :::.:::::: ::.: ::: :.....  .....:: .::.:..   
XP_011 SSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGLISHVLEQ
             100       110       120       130       140       150 

             220       230       240       250       260       270 
pF1KE2 ----ETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDD
           ..  ..:.. :...  .. ... .:: ..: ..:. :. :  .:.  . .:. : :
XP_011 NQEGDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKD
             160       170       180       190       200       210 

             280       290
pF1KE2 RKEGMTAFVEKRKANFKDQ
       : ::. :: :::   .: .
XP_011 RLEGLLAFKEKRPPRYKGE
             220       230

>>XP_016870339 (OMIM: 250950,600529) PREDICTED: methylgl  (230 aa)
 initn: 353 init1: 264 opt: 416  Z-score: 527.4  bits: 105.2 E(85289): 1.2e-22
Smith-Waterman score: 416; 32.8% identity (67.2% similar) in 229 aa overlap (69-290:2-230)

       40        50        60        70        80        90        
pF1KE2 EKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGG-DKAFAAG
                                     :..:. ... :  : .:.. .     : ::
XP_016                              MLSKAVDALKSDKKVRTIIIRSEVPGIFCAG
                                            10        20        30 

       100       110         120       130       140       150     
pF1KE2 ADIKEMQNLSFQDC--YSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAG
       ::.::  ..: ..   . ::.    . ....  :.:::..: :.::: :::. :::  :.
XP_016 ADLKERAKMSSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAA
              40        50        60        70        80        90 

         160       170       180       190       200       210     
pF1KE2 EKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPV
        .:...  :  .. :::.:::::: ::.: ::: :.....  .....:: .::.:..   
XP_016 SSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGLISHVLEQ
             100       110       120       130       140       150 

             220       230       240       250       260       270 
pF1KE2 ----ETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDD
           ..  ..:.. :...  .. ... .:: ..: ..:. :. :  .:.  . .:. : :
XP_016 NQEGDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKD
             160       170       180       190       200       210 

             280       290
pF1KE2 RKEGMTAFVEKRKANFKDQ
       : ::. :: :::   .: .
XP_016 RLEGLLAFKEKRPPRYKGE
             220       230

>>NP_001957 (OMIM: 607037,615605) peroxisomal bifunction  (723 aa)
 initn: 419 init1: 257 opt: 379  Z-score: 473.8  bits: 96.9 E(85289): 1.2e-19
Smith-Waterman score: 379; 35.1% identity (66.5% similar) in 194 aa overlap (37-230:1-189)

         10        20        30        40        50        60      
pF1KE2 LLSCVRGPLRPPVRCPAWRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLI
                                     .::    .:...::.:  :  .::.   :.
NP_001                               MAEYTRLHNALALIRLRNPP-VNAISTTLL
                                             10        20          

         70        80        90       100       110       120      
pF1KE2 DELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQV
        .....:.    : .. :::. :..  :.:::::.   ..:    ..  . .  :.. . 
NP_001 RDIKEGLQKAVIDHTIKAIVICGAEGKFSAGADIR---GFSAPRTFGLTLGHVVDEIQRN
      30        40        50        60           70        80      

        130       140       150       160       170       180      
pF1KE2 KKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKS
       .:::.::..:.::::: :::. :    :  .:: . ::. .: .::: ::: : : .:  
NP_001 EKPVVAAIQGMAFGGGLELALGCHYRIAHAEAQVGLPEVTLGLLPGARGTQLLPRLTGVP
         90       100       110       120       130       140      

        190       200       210       220       230       240      
pF1KE2 LAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNA
        :.... .: :: :..: . :...:.   .  :::::. :....                
NP_001 AALDLITSGRRILADEALKLGILDKVVNSDP-VEEAIRFAQRVSDQPLESRRLCNKPIQS
        150       160       170        180       190       200     

        250       260       270       280       290                
pF1KE2 AFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKANFKDQ                
                                                                   
NP_001 LPNMDSIFSEALLKMRRQHPGCLAQEACVRAVQAAVQYPYEVGIKKEEELFLYLLQSGQA
         210       220       230       240       250       260     

>>XP_016870338 (OMIM: 250950,600529) PREDICTED: methylgl  (323 aa)
 initn: 361 init1: 264 opt: 367  Z-score: 463.8  bits: 93.9 E(85289): 4.3e-19
Smith-Waterman score: 392; 31.0% identity (62.7% similar) in 255 aa overlap (43-290:85-323)

             20        30        40        50        60        70  
pF1KE2 GPLRPPVRCPAWRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQA
                                     .:  . .. .::  . :.:  .::  :..:
XP_016 VPAAGGPAPKRGYSSEMKTEDELRVRHLEEENRGIVVLGINRAYGKNSLSKNLIKMLSKA
           60        70        80        90       100       110    

             80        90        100       110         120         
pF1KE2 LKTFEEDPAVGAIVLTGG-DKAFAAGADIKEMQNLSFQDC--YSSKFLKHWDHLTQVKKP
       . ... :  : .:.. .     : ::::.::  ..: ..   . ::.    . ....  :
XP_016 VDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDIANLPVP
          120       130       140       150       160       170    

     130       140       150       160       170       180         
pF1KE2 VIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAM
       .:::..: :.::: :::. :::  :. .:...  :  .. :::.:::::: ::.: ::: 
XP_016 TIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAK
          180       190       200       210       220       230    

     190       200       210           220       230       240     
pF1KE2 EMVLTGDRISAQDAKQAGLVSKICPV----ETLVEEAIQCAEKIASNSKIVVAMAKESVN
       :.....  .....:: .::.:..       ..  ..:.. :...  .. ... .:: ..:
XP_016 ELIFSARVLDGKEAKAVGLISHVLEQNQEGDAAYRKALDLAREFLPQGPVAMRVAKLAIN
          240       250       260       270       280       290    

         250       260       270       280       290
pF1KE2 AAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKANFKDQ
        ..:                :. : :: ::. :: :::   .: .
XP_016 QGME----------------TIPTKDRLEGLLAFKEKRPPRYKGE
                          300       310       320   

>>NP_001293119 (OMIM: 250950,600529) methylglutaconyl-Co  (310 aa)
 initn: 305 init1: 254 opt: 365  Z-score: 461.6  bits: 93.4 E(85289): 5.7e-19
Smith-Waterman score: 365; 36.1% identity (70.5% similar) in 166 aa overlap (129-290:145-310)

      100       110       120       130       140       150        
pF1KE2 DIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKA
                                     :.:::..: :.::: :::. :::  :. .:
NP_001 VDALKSDKKVRTIIIRSEVPGIFCAANLPVPTIAAIDGLALGGGLELALACDIRVAASSA
          120       130       140       150       160       170    

      160       170       180       190       200       210        
pF1KE2 QFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPV---
       ...  :  .. :::.:::::: ::.: ::: :.....  .....:: .::.:..      
NP_001 KMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGLISHVLEQNQE
          180       190       200       210       220       230    

          220       230       240       250       260       270    
pF1KE2 -ETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKE
        ..  ..:.. :...  .. ... .:: ..: ..:. :. :  .:.  . .:. : :: :
NP_001 GDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLE
          240       250       260       270       280       290    

          280       290
pF1KE2 GMTAFVEKRKANFKDQ
       :. :: :::   .: .
NP_001 GLLAFKEKRPPRYKGE
          300       310

>>XP_006717213 (OMIM: 250950,600529) PREDICTED: methylgl  (320 aa)
 initn: 305 init1: 254 opt: 365  Z-score: 461.4  bits: 93.5 E(85289): 5.8e-19
Smith-Waterman score: 365; 36.1% identity (70.5% similar) in 166 aa overlap (129-290:155-320)

      100       110       120       130       140       150        
pF1KE2 DIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKA
                                     :.:::..: :.::: :::. :::  :. .:
XP_006 VDALKSDKKVRTIIIRSEVPGIFCAANLPVPTIAAIDGLALGGGLELALACDIRVAASSA
          130       140       150       160       170       180    

      160       170       180       190       200       210        
pF1KE2 QFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPV---
       ...  :  .. :::.:::::: ::.: ::: :.....  .....:: .::.:..      
XP_006 KMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGLISHVLEQNQE
          190       200       210       220       230       240    

          220       230       240       250       260       270    
pF1KE2 -ETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKE
        ..  ..:.. :...  .. ... .:: ..: ..:. :. :  .:.  . .:. : :: :
XP_006 GDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLE
          250       260       270       280       290       300    

          280       290
pF1KE2 GMTAFVEKRKANFKDQ
       :. :: :::   .: .
XP_006 GLLAFKEKRPPRYKGE
          310       320

>>XP_005252124 (OMIM: 250950,600529) PREDICTED: methylgl  (333 aa)
 initn: 361 init1: 264 opt: 362  Z-score: 457.4  bits: 92.8 E(85289): 9.8e-19
Smith-Waterman score: 387; 31.3% identity (63.1% similar) in 249 aa overlap (49-290:101-333)

       20        30        40        50        60        70        
pF1KE2 VRCPAWRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEE
                                     .. .::  . :.:  .::  :..:. ... 
XP_005 MKTEDELRVRHLEEENRDSSSMAADHYRIVVLGINRAYGKNSLSKNLIKMLSKAVDALKS
               80        90       100       110       120       130

       80        90        100       110         120       130     
pF1KE2 DPAVGAIVLTGG-DKAFAAGADIKEMQNLSFQDC--YSSKFLKHWDHLTQVKKPVIAAVN
       :  : .:.. .     : ::::.::  ..: ..   . ::.    . ....  :.:::..
XP_005 DKKVRTIIIRSEVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDIANLPVPTIAAID
              140       150       160       170       180       190

         140       150       160       170       180       190     
pF1KE2 GYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTG
       : :.::: :::. :::  :. .:...  :  .. :::.:::::: ::.: ::: :.....
XP_005 GLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSA
              200       210       220       230       240       250

         200       210           220       230       240       250 
pF1KE2 DRISAQDAKQAGLVSKICPV----ETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMT
         .....:: .::.:..       ..  ..:.. :...  .. ... .:: ..: ..:  
XP_005 RVLDGKEAKAVGLISHVLEQNQEGDAAYRKALDLAREFLPQGPVAMRVAKLAINQGME--
              260       270       280       290       300          

             260       270       280       290
pF1KE2 LTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKANFKDQ
                     :. : :: ::. :: :::   .: .
XP_005 --------------TIPTKDRLEGLLAFKEKRPPRYKGE
                    310       320       330   




290 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 15:17:27 2016 done: Sun Nov  6 15:17:28 2016
 Total Scan time:  6.140 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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