Result of FASTA (omim) for pF1KE0947
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0947, 385 aa
  1>>>pF1KE0947     385 - 385 aa - 385 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.1232+/-0.000571; mu= -0.7985+/- 0.034
 mean_var=607.9323+/-135.181, 0's: 0 Z-trim(117.4): 1634  B-trim: 0 in 0/52
 Lambda= 0.052017
 statistics sampled from 27063 (29419) to 27063 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.686), E-opt: 0.2 (0.345), width:  16
 Scan time:  8.760

The best scores are:                                      opt bits E(85289)
NP_006733 (OMIM: 177015) serine/threonine-protein  ( 424) 1583 134.4 4.8e-31
XP_006717546 (OMIM: 607957) PREDICTED: calcium/cal ( 355)  852 79.4 1.5e-14
NP_065130 (OMIM: 607957) calcium/calmodulin-depend ( 357)  852 79.4 1.5e-14
XP_006717545 (OMIM: 607957) PREDICTED: calcium/cal ( 362)  852 79.4 1.5e-14
NP_705718 (OMIM: 607957) calcium/calmodulin-depend ( 385)  852 79.5 1.5e-14
NP_001034671 (OMIM: 300680) calcium/calmodulin-dep ( 426)  836 78.3 3.6e-14
XP_016884766 (OMIM: 300680) PREDICTED: calcium/cal ( 426)  836 78.3 3.6e-14
NP_003647 (OMIM: 604998) calcium/calmodulin-depend ( 370)  833 78.0   4e-14
XP_005265573 (OMIM: 604998) PREDICTED: calcium/cal ( 413)  833 78.1 4.2e-14
XP_006717544 (OMIM: 607957) PREDICTED: calcium/cal ( 366)  829 77.7 4.9e-14
XP_011517893 (OMIM: 607957) PREDICTED: calcium/cal ( 372)  829 77.7 4.9e-14
XP_005274708 (OMIM: 300680) PREDICTED: calcium/cal ( 343)  795 75.1 2.8e-13
XP_011529413 (OMIM: 300680) PREDICTED: calcium/cal ( 343)  795 75.1 2.8e-13
XP_011529412 (OMIM: 300680) PREDICTED: calcium/cal ( 343)  795 75.1 2.8e-13
XP_016884767 (OMIM: 300680) PREDICTED: calcium/cal ( 343)  795 75.1 2.8e-13
XP_011529414 (OMIM: 300680) PREDICTED: calcium/cal ( 343)  795 75.1 2.8e-13
XP_011529409 (OMIM: 300680) PREDICTED: calcium/cal ( 343)  795 75.1 2.8e-13
XP_016884768 (OMIM: 300680) PREDICTED: calcium/cal ( 343)  795 75.1 2.8e-13
XP_006724872 (OMIM: 300680) PREDICTED: calcium/cal ( 343)  795 75.1 2.8e-13
NP_001129212 (OMIM: 300680) calcium/calmodulin-dep ( 360)  795 75.1 2.8e-13
XP_011529410 (OMIM: 300680) PREDICTED: calcium/cal ( 361)  795 75.1 2.8e-13
XP_016857355 (OMIM: 614994) PREDICTED: calcium/cal ( 476)  776 73.9 8.7e-13
NP_065172 (OMIM: 614994) calcium/calmodulin-depend ( 476)  776 73.9 8.7e-13
NP_001310304 (OMIM: 114080) calcium/calmodulin-dep ( 473)  762 72.9 1.8e-12
NP_001310303 (OMIM: 114080) calcium/calmodulin-dep ( 473)  762 72.9 1.8e-12
NP_001735 (OMIM: 114080) calcium/calmodulin-depend ( 473)  762 72.9 1.8e-12
XP_011517895 (OMIM: 607957) PREDICTED: calcium/cal ( 311)  718 69.3 1.5e-11
XP_011517894 (OMIM: 607957) PREDICTED: calcium/cal ( 315)  718 69.3 1.5e-11
XP_016862843 (OMIM: 604998) PREDICTED: calcium/cal ( 326)  711 68.8 2.1e-11
XP_005265574 (OMIM: 604998) PREDICTED: calcium/cal ( 369)  711 68.9 2.3e-11
NP_001182345 (OMIM: 604742) serine/threonine-prote ( 433)  696 67.9 5.3e-11
XP_016863321 (OMIM: 613166) PREDICTED: serine/thre ( 717)  697 68.3 6.4e-11
NP_001317001 (OMIM: 604742) serine/threonine-prote ( 740)  696 68.3 6.9e-11
NP_001317000 (OMIM: 604742) serine/threonine-prote ( 740)  696 68.3 6.9e-11
NP_001035350 (OMIM: 613166) serine/threonine-prote ( 766)  696 68.3   7e-11
NP_001035351 (OMIM: 613166) serine/threonine-prote ( 783)  696 68.3 7.1e-11
NP_001182344 (OMIM: 604742) serine/threonine-prote ( 422)  690 67.4 7.2e-11
XP_005262843 (OMIM: 613166) PREDICTED: serine/thre ( 765)  695 68.2 7.4e-11
XP_005262842 (OMIM: 613166) PREDICTED: serine/thre ( 782)  695 68.2 7.5e-11
NP_001307076 (OMIM: 614993) caM kinase-like vesicl ( 470)  690 67.5 7.6e-11
NP_076951 (OMIM: 614993) caM kinase-like vesicle-a ( 501)  690 67.5 7.8e-11
NP_004725 (OMIM: 604742) serine/threonine-protein  ( 729)  690 67.8 9.4e-11
XP_016876336 (OMIM: 604742) PREDICTED: serine/thre ( 708)  689 67.7 9.7e-11
XP_016871928 (OMIM: 607957) PREDICTED: calcium/cal ( 260)  656 64.5 3.4e-10
XP_016871927 (OMIM: 607957) PREDICTED: calcium/cal ( 288)  656 64.5 3.5e-10
XP_011517897 (OMIM: 607957) PREDICTED: calcium/cal ( 288)  656 64.5 3.5e-10
NP_001305866 (OMIM: 601685) ribosomal protein S6 k ( 635)  636 63.6 1.5e-09
NP_001305867 (OMIM: 601685) ribosomal protein S6 k ( 644)  636 63.6 1.5e-09
NP_208382 (OMIM: 613167) serine/threonine-protein  ( 648)  636 63.7 1.5e-09
XP_011532469 (OMIM: 613167) PREDICTED: serine/thre ( 648)  636 63.7 1.5e-09


>>NP_006733 (OMIM: 177015) serine/threonine-protein kina  (424 aa)
 initn: 1610 init1: 1556 opt: 1583  Z-score: 678.3  bits: 134.4 E(85289): 4.8e-31
Smith-Waterman score: 1583; 65.4% identity (84.6% similar) in 370 aa overlap (9-375:48-412)

                                     10        20        30        
pF1KE0                       MGCGASRKVVPGPPALAWAKHEGQNQAGVGGAGPGPEA
                                     :  : :: .   :   .   .: . : :  
NP_006 LDLVKKVEPFSGTKSDVYKHFITEVDSVGPVKAGFPAASQYAHPCPGPPTAGHTEP-P--
        20        30        40        50        60        70       

       40        50        60        70        80        90        
pF1KE0 AAQAAQRIQVARFRAKFDPRVLARYDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETRE
        ..  .: .::..:::::::: :.:::::::: ::::::::::...:..:.:::..::. 
NP_006 -SEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKY
            80        90       100       110       120       130   

      100       110       120       130       140       150        
pF1KE0 REGREACVSELSVLRRVSHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTER
       :::::.: ::: ::::: :  :.::.:.:::...::::::::::::::::.::.::::::
NP_006 REGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTER
           140       150       160       170       180       190   

      160       170       180       190       200       210        
pF1KE0 DAVRILQMVADGIRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGDWT
       ::.:.:::: ::.:::::: ::::.:::::::::::: .:::.::::::: . ::. :  
NP_006 DATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCL
           200       210       220       230       240       250   

      220       230       240       250       260       270        
pF1KE0 MKTLCGTPEYIAPEVLLRKPYTSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGK
       ::: ::::::::::::.:::::..:::::::::.: :::: .::.:...:::::.::.::
NP_006 MKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGK
           260       270       280       290       300       310   

      280       290       300       310       320       330        
pF1KE0 YNYTGEPWPSISHLAKDFIDKLLILEAGHRMSAGQALDHPWVITMAAGSSMKNLQRAISR
       :.:.::::::.:.:::::::.:: .. : ::.: ::: ::::..:::.::::::.:.::.
NP_006 YSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMKNLHRSISQ
           320       330       340       350       360       370   

      340       350          360       370       380       
pF1KE0 NLMQRASPHSQSPGSAQS---SKSHYSHKSRHMWSKRNLRIVESPLSALL  
       ::..::: . ::  ::::   :.:  :.:::..  .:.::            
NP_006 NLLKRASSRCQSTKSAQSTRSSRSTRSNKSRRV-RERELRELNLRYQQQYNG
           380       390       400        410       420    

>>XP_006717546 (OMIM: 607957) PREDICTED: calcium/calmodu  (355 aa)
 initn: 828 init1: 378 opt: 852  Z-score: 382.4  bits: 79.4 E(85289): 1.5e-14
Smith-Waterman score: 852; 46.2% identity (78.1% similar) in 279 aa overlap (63-337:23-294)

             40        50        60        70        80        90  
pF1KE0 GPGPEAAAQAAQRIQVARFRAKFDPRVLARYDIKALIGTGSFSRVVRVEQKTTKKPFAIK
                                     ...:  .:::.::.:: .:.:.: : ::.:
XP_006         MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVK
                       10        20        30        40        50  

            100        110       120       130       140       150 
pF1KE0 VMETREREGREACV-SELSVLRRVSHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIA
        .  .  .:.:. . .:..:::...:. :: : .:.:. ...:.::.:..:::::::.. 
XP_006 CIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVE
             60        70        80        90       100       110  

             160       170       180       190       200        210
pF1KE0 QGSFTERDAVRILQMVADGIRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLA-YS
       .: .::.::  ....: :.. ::: . :.::.:::::::::   :::::.:.::::. . 
XP_006 KGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKME
            120       130       140       150       160       170  

              220       230       240       250       260       270
pF1KE0 GKKSGDWTMKTLCGTPEYIAPEVLLRKPYTSAVDMWALGVITYALLSGFLPFDDESQTRL
       ::  :: .:.: :::: :.::::: .:::..::: :..:::.: :: :. :: ::....:
XP_006 GK--GD-VMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKL
               180       190       200       210       220         

              280       290       300       310       320          
pF1KE0 YRKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAGHRMSAGQALDHPWVITMAAGSSM-
       ...:::..:.. .  : .::  ::::: .:.  . ..:..  ::  :::.    ::..  
XP_006 FEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI----AGDTAL
     230       240       250       260       270           280     

      330       340       350       360       370       380        
pF1KE0 -KNLQRAISRNLMQRASPHSQSPGSAQSSKSHYSHKSRHMWSKRNLRIVESPLSALL   
        ::.....:                                                   
XP_006 NKNIHESVSAQIRKNFAKSKWRQAFNATAVVRHMRKLHLGSSLDSSNASVSSSLSLASQK
         290       300       310       320       330       340     

>>NP_065130 (OMIM: 607957) calcium/calmodulin-dependent   (357 aa)
 initn: 828 init1: 378 opt: 852  Z-score: 382.4  bits: 79.4 E(85289): 1.5e-14
Smith-Waterman score: 852; 46.2% identity (78.1% similar) in 279 aa overlap (63-337:23-294)

             40        50        60        70        80        90  
pF1KE0 GPGPEAAAQAAQRIQVARFRAKFDPRVLARYDIKALIGTGSFSRVVRVEQKTTKKPFAIK
                                     ...:  .:::.::.:: .:.:.: : ::.:
NP_065         MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVK
                       10        20        30        40        50  

            100        110       120       130       140       150 
pF1KE0 VMETREREGREACV-SELSVLRRVSHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIA
        .  .  .:.:. . .:..:::...:. :: : .:.:. ...:.::.:..:::::::.. 
NP_065 CIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVE
             60        70        80        90       100       110  

             160       170       180       190       200        210
pF1KE0 QGSFTERDAVRILQMVADGIRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLA-YS
       .: .::.::  ....: :.. ::: . :.::.:::::::::   :::::.:.::::. . 
NP_065 KGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKME
            120       130       140       150       160       170  

              220       230       240       250       260       270
pF1KE0 GKKSGDWTMKTLCGTPEYIAPEVLLRKPYTSAVDMWALGVITYALLSGFLPFDDESQTRL
       ::  :: .:.: :::: :.::::: .:::..::: :..:::.: :: :. :: ::....:
NP_065 GK--GD-VMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKL
               180       190       200       210       220         

              280       290       300       310       320          
pF1KE0 YRKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAGHRMSAGQALDHPWVITMAAGSSM-
       ...:::..:.. .  : .::  ::::: .:.  . ..:..  ::  :::.    ::..  
NP_065 FEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI----AGDTAL
     230       240       250       260       270           280     

      330       340       350       360       370       380        
pF1KE0 -KNLQRAISRNLMQRASPHSQSPGSAQSSKSHYSHKSRHMWSKRNLRIVESPLSALL   
        ::.....:                                                   
NP_065 NKNIHESVSAQIRKNFAKSKWRQAFNATAVVRHMRKLHLGSSLDSSNASVSSSLSLASQK
         290       300       310       320       330       340     

>>XP_006717545 (OMIM: 607957) PREDICTED: calcium/calmodu  (362 aa)
 initn: 805 init1: 378 opt: 852  Z-score: 382.4  bits: 79.4 E(85289): 1.5e-14
Smith-Waterman score: 852; 46.2% identity (78.1% similar) in 279 aa overlap (63-337:23-294)

             40        50        60        70        80        90  
pF1KE0 GPGPEAAAQAAQRIQVARFRAKFDPRVLARYDIKALIGTGSFSRVVRVEQKTTKKPFAIK
                                     ...:  .:::.::.:: .:.:.: : ::.:
XP_006         MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVK
                       10        20        30        40        50  

            100        110       120       130       140       150 
pF1KE0 VMETREREGREACV-SELSVLRRVSHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIA
        .  .  .:.:. . .:..:::...:. :: : .:.:. ...:.::.:..:::::::.. 
XP_006 CIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVE
             60        70        80        90       100       110  

             160       170       180       190       200        210
pF1KE0 QGSFTERDAVRILQMVADGIRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLA-YS
       .: .::.::  ....: :.. ::: . :.::.:::::::::   :::::.:.::::. . 
XP_006 KGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKME
            120       130       140       150       160       170  

              220       230       240       250       260       270
pF1KE0 GKKSGDWTMKTLCGTPEYIAPEVLLRKPYTSAVDMWALGVITYALLSGFLPFDDESQTRL
       ::  :: .:.: :::: :.::::: .:::..::: :..:::.: :: :. :: ::....:
XP_006 GK--GD-VMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKL
               180       190       200       210       220         

              280       290       300       310       320          
pF1KE0 YRKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAGHRMSAGQALDHPWVITMAAGSSM-
       ...:::..:.. .  : .::  ::::: .:.  . ..:..  ::  :::.    ::..  
XP_006 FEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI----AGDTAL
     230       240       250       260       270           280     

      330       340       350       360       370       380        
pF1KE0 -KNLQRAISRNLMQRASPHSQSPGSAQSSKSHYSHKSRHMWSKRNLRIVESPLSALL   
        ::.....:                                                   
XP_006 NKNIHESVSAQIRKNFAKSKWRQAFNATAVVRHMRKLHLGSSLDSSNVWHLPRSVVSFLL
         290       300       310       320       330       340     

>>NP_705718 (OMIM: 607957) calcium/calmodulin-dependent   (385 aa)
 initn: 828 init1: 378 opt: 852  Z-score: 382.1  bits: 79.5 E(85289): 1.5e-14
Smith-Waterman score: 852; 46.2% identity (78.1% similar) in 279 aa overlap (63-337:23-294)

             40        50        60        70        80        90  
pF1KE0 GPGPEAAAQAAQRIQVARFRAKFDPRVLARYDIKALIGTGSFSRVVRVEQKTTKKPFAIK
                                     ...:  .:::.::.:: .:.:.: : ::.:
NP_705         MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVK
                       10        20        30        40        50  

            100        110       120       130       140       150 
pF1KE0 VMETREREGREACV-SELSVLRRVSHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIA
        .  .  .:.:. . .:..:::...:. :: : .:.:. ...:.::.:..:::::::.. 
NP_705 CIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVE
             60        70        80        90       100       110  

             160       170       180       190       200        210
pF1KE0 QGSFTERDAVRILQMVADGIRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLA-YS
       .: .::.::  ....: :.. ::: . :.::.:::::::::   :::::.:.::::. . 
NP_705 KGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKME
            120       130       140       150       160       170  

              220       230       240       250       260       270
pF1KE0 GKKSGDWTMKTLCGTPEYIAPEVLLRKPYTSAVDMWALGVITYALLSGFLPFDDESQTRL
       ::  :: .:.: :::: :.::::: .:::..::: :..:::.: :: :. :: ::....:
NP_705 GK--GD-VMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKL
               180       190       200       210       220         

              280       290       300       310       320          
pF1KE0 YRKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAGHRMSAGQALDHPWVITMAAGSSM-
       ...:::..:.. .  : .::  ::::: .:.  . ..:..  ::  :::.    ::..  
NP_705 FEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI----AGDTAL
     230       240       250       260       270           280     

      330       340       350       360       370       380        
pF1KE0 -KNLQRAISRNLMQRASPHSQSPGSAQSSKSHYSHKSRHMWSKRNLRIVESPLSALL   
        ::.....:                                                   
NP_705 NKNIHESVSAQIRKNFAKSKWRQAFNATAVVRHMRKLHLGSSLDSSNASVSSSLSLASQK
         290       300       310       320       330       340     

>>NP_001034671 (OMIM: 300680) calcium/calmodulin-depende  (426 aa)
 initn: 717 init1: 368 opt: 836  Z-score: 375.3  bits: 78.3 E(85289): 3.6e-14
Smith-Waterman score: 836; 40.2% identity (68.9% similar) in 351 aa overlap (4-344:38-383)

                                          10           20        30
pF1KE0                            MGCGASRKVVPGP---PALAWAKHEGQNQAGVG
                                     : :..   ::   ::    .. .. ..:.:
NP_001 VAGSACPRRGGEGRDWKAESLADLWPKSSPGDSHRWCKGPGAGPAGPQLREAARASSGLG
        10        20        30        40        50        60       

               40        50        60        70        80        90
pF1KE0 GAGPGPEAAAQAAQRIQVARFRAKFDPRVLARYDIKALIGTGSFSRVVRVEQKTTKKPFA
       :.:  :      :  .:   .  :    . . :.:.  .:.:.::.:: .... . .  :
NP_001 GGGRHPSRIPAIA--LQDMLLLKKHTEDISSVYEIRERLGSGAFSEVVLAQERGSAHLVA
        70        80          90       100       110       120     

              100        110       120       130       140         
pF1KE0 IKVMETREREGREACV-SELSVLRRVSHRYIVQLMEIFETEDQVYMVMELATGGELFDRL
       .: .  .  .:.:: : .:..::::.::  :: : .. :. ...:..:::.::::::::.
NP_001 LKCIPKKALRGKEALVENEIAVLRRISHPNIVALEDVHESPSHLYLAMELVTGGELFDRI
         130       140       150       160       170       180     

     150       160       170       180       190       200         
pF1KE0 IAQGSFTERDAVRILQMVADGIRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLAY
       . .::.::.:: ... .:  .. :::.: :.::.::::::::  : :.:::...::::  
NP_001 MERGSYTEKDASHLVGQVLGAVSYLHSLGIVHRDLKPENLLYATPFEDSKIMVSDFGL--
         190       200       210       220       230       240     

     210       220       230       240       250       260         
pF1KE0 SGKKSGDWTMKTLCGTPEYIAPEVLLRKPYTSAVDMWALGVITYALLSGFLPFDDESQTR
       :  ..:.  . : :::: :.:::.: .::: .:::.::::::.: :: :. :: :::. .
NP_001 SKIQAGNM-LGTACGTPGYVAPELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPE
           250        260       270       280       290       300  

     270       280       290       300       310       320         
pF1KE0 LYRKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAGHRMSAGQALDHPWVITMAA----
       :. .::...:.. .  : .::. ::::: .::  .  .:..  ::: : :.   .:    
NP_001 LFSQILRASYEFDSPFWDDISESAKDFIRHLLERDPQKRFTCQQALRHLWISGDTAFDRD
            310       320       330       340       350       360  

           330       340       350       360       370       380   
pF1KE0 --GSSMKNLQRAISRNLMQRASPHSQSPGSAQSSKSHYSHKSRHMWSKRNLRIVESPLSA
         ::  ..... ..:.  .::                                       
NP_001 ILGSVSEQIRKNFARTHWKRAFNATSFLRHIRKLGQIPEGEGASEQGMARHSHSGLRAGQ
            370       380       390       400       410       420  

>>XP_016884766 (OMIM: 300680) PREDICTED: calcium/calmodu  (426 aa)
 initn: 717 init1: 368 opt: 836  Z-score: 375.3  bits: 78.3 E(85289): 3.6e-14
Smith-Waterman score: 836; 40.2% identity (68.9% similar) in 351 aa overlap (4-344:38-383)

                                          10           20        30
pF1KE0                            MGCGASRKVVPGP---PALAWAKHEGQNQAGVG
                                     : :..   ::   ::    .. .. ..:.:
XP_016 VAGSACPRRGGEGRDWKAESLADLWPKSSPGDSHRWCKGPGAGPAGPQLREAARASSGLG
        10        20        30        40        50        60       

               40        50        60        70        80        90
pF1KE0 GAGPGPEAAAQAAQRIQVARFRAKFDPRVLARYDIKALIGTGSFSRVVRVEQKTTKKPFA
       :.:  :      :  .:   .  :    . . :.:.  .:.:.::.:: .... . .  :
XP_016 GGGRHPSRIPAIA--LQDMLLLKKHTEDISSVYEIRERLGSGAFSEVVLAQERGSAHLVA
        70        80          90       100       110       120     

              100        110       120       130       140         
pF1KE0 IKVMETREREGREACV-SELSVLRRVSHRYIVQLMEIFETEDQVYMVMELATGGELFDRL
       .: .  .  .:.:: : .:..::::.::  :: : .. :. ...:..:::.::::::::.
XP_016 LKCIPKKALRGKEALVENEIAVLRRISHPNIVALEDVHESPSHLYLAMELVTGGELFDRI
         130       140       150       160       170       180     

     150       160       170       180       190       200         
pF1KE0 IAQGSFTERDAVRILQMVADGIRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLAY
       . .::.::.:: ... .:  .. :::.: :.::.::::::::  : :.:::...::::  
XP_016 MERGSYTEKDASHLVGQVLGAVSYLHSLGIVHRDLKPENLLYATPFEDSKIMVSDFGL--
         190       200       210       220       230       240     

     210       220       230       240       250       260         
pF1KE0 SGKKSGDWTMKTLCGTPEYIAPEVLLRKPYTSAVDMWALGVITYALLSGFLPFDDESQTR
       :  ..:.  . : :::: :.:::.: .::: .:::.::::::.: :: :. :: :::. .
XP_016 SKIQAGNM-LGTACGTPGYVAPELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPE
           250        260       270       280       290       300  

     270       280       290       300       310       320         
pF1KE0 LYRKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAGHRMSAGQALDHPWVITMAA----
       :. .::...:.. .  : .::. ::::: .::  .  .:..  ::: : :.   .:    
XP_016 LFSQILRASYEFDSPFWDDISESAKDFIRHLLERDPQKRFTCQQALRHLWISGDTAFDRD
            310       320       330       340       350       360  

           330       340       350       360       370       380   
pF1KE0 --GSSMKNLQRAISRNLMQRASPHSQSPGSAQSSKSHYSHKSRHMWSKRNLRIVESPLSA
         ::  ..... ..:.  .::                                       
XP_016 ILGSVSEQIRKNFARTHWKRAFNATSFLRHIRKLGQIPEGEGASEQGMARHSHSGLRAGQ
            370       380       390       400       410       420  

>>NP_003647 (OMIM: 604998) calcium/calmodulin-dependent   (370 aa)
 initn: 830 init1: 366 opt: 833  Z-score: 374.6  bits: 78.0 E(85289): 4e-14
Smith-Waterman score: 833; 43.6% identity (75.8% similar) in 298 aa overlap (46-340:5-294)

          20        30        40        50        60        70     
pF1KE0 LAWAKHEGQNQAGVGGAGPGPEAAAQAAQRIQVARFRAKFDPRVLARYDIKALIGTGSFS
                                     ..  :..   : : .  ::.. ..:::.::
NP_003                           MLGAVEGPRWKQAEDIRDI--YDFRDVLGTGAFS
                                         10          20        30  

          80        90       100        110       120       130    
pF1KE0 RVVRVEQKTTKKPFAIKVMETREREGREACV-SELSVLRRVSHRYIVQLMEIFETEDQVY
       .:. .:.: :.:  ::: .  .  ::.:. . .:..::....:  :: : .:.:.  ..:
NP_003 EVILAEDKRTQKLVAIKCIAKEALEGKEGSMENEIAVLHKIKHPNIVALDDIYESGGHLY
             40        50        60        70        80        90  

          140       150       160       170       180       190    
pF1KE0 MVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQITHRNLKPENLLYYHP
       ..:.:..:::::::.. .: .::::: :.. .: :...::: : :.::.:::::::::  
NP_003 LIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSL
            100       110       120       130       140       150  

          200       210       220       230       240       250    
pF1KE0 GEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYTSAVDMWALGVITYA
        :.:::.:.::::  :  ..   ...: :::: :.::::: .:::..::: :..:::.: 
NP_003 DEDSKIMISDFGL--SKMEDPGSVLSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYI
            160         170       180       190       200       210

          260       270       280       290       300       310    
pF1KE0 LLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAGHRMSAGQA
       :: :. :: ::....:...:::..:.. .  : .::  ::::: .:.  .  .:..  ::
NP_003 LLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQA
              220       230       240       250       260       270

          320         330       340       350       360       370  
pF1KE0 LDHPWVITMAAGSSM--KNLQRAISRNLMQRASPHSQSPGSAQSSKSHYSHKSRHMWSKR
       :.:::.    ::..   ::.....:...                                
NP_003 LQHPWI----AGDTALDKNIHQSVSEQIKKNFAKSKWKQAFNATAVVRHMRKLQLGTSQE
                  280       290       300       310       320      

>>XP_005265573 (OMIM: 604998) PREDICTED: calcium/calmodu  (413 aa)
 initn: 845 init1: 366 opt: 833  Z-score: 374.2  bits: 78.1 E(85289): 4.2e-14
Smith-Waterman score: 833; 43.6% identity (75.8% similar) in 298 aa overlap (46-340:5-294)

          20        30        40        50        60        70     
pF1KE0 LAWAKHEGQNQAGVGGAGPGPEAAAQAAQRIQVARFRAKFDPRVLARYDIKALIGTGSFS
                                     ..  :..   : : .  ::.. ..:::.::
XP_005                           MLGAVEGPRWKQAEDIRDI--YDFRDVLGTGAFS
                                         10          20        30  

          80        90       100        110       120       130    
pF1KE0 RVVRVEQKTTKKPFAIKVMETREREGREACV-SELSVLRRVSHRYIVQLMEIFETEDQVY
       .:. .:.: :.:  ::: .  .  ::.:. . .:..::....:  :: : .:.:.  ..:
XP_005 EVILAEDKRTQKLVAIKCIAKEALEGKEGSMENEIAVLHKIKHPNIVALDDIYESGGHLY
             40        50        60        70        80        90  

          140       150       160       170       180       190    
pF1KE0 MVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQITHRNLKPENLLYYHP
       ..:.:..:::::::.. .: .::::: :.. .: :...::: : :.::.:::::::::  
XP_005 LIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSL
            100       110       120       130       140       150  

          200       210       220       230       240       250    
pF1KE0 GEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYTSAVDMWALGVITYA
        :.:::.:.::::  :  ..   ...: :::: :.::::: .:::..::: :..:::.: 
XP_005 DEDSKIMISDFGL--SKMEDPGSVLSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYI
            160         170       180       190       200       210

          260       270       280       290       300       310    
pF1KE0 LLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAGHRMSAGQA
       :: :. :: ::....:...:::..:.. .  : .::  ::::: .:.  .  .:..  ::
XP_005 LLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQA
              220       230       240       250       260       270

          320         330       340       350       360       370  
pF1KE0 LDHPWVITMAAGSSM--KNLQRAISRNLMQRASPHSQSPGSAQSSKSHYSHKSRHMWSKR
       :.:::.    ::..   ::.....:...                                
XP_005 LQHPWI----AGDTALDKNIHQSVSEQIKKNFAKSKWKQAFNATAVVRHMRKLQLGTSQE
                  280       290       300       310       320      

>>XP_006717544 (OMIM: 607957) PREDICTED: calcium/calmodu  (366 aa)
 initn: 806 init1: 378 opt: 829  Z-score: 373.0  bits: 77.7 E(85289): 4.9e-14
Smith-Waterman score: 829; 46.5% identity (78.2% similar) in 271 aa overlap (71-337:12-275)

               50        60        70        80        90       100
pF1KE0 QAAQRIQVARFRAKFDPRVLARYDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETRERE
                                     .:.::.:: .:.:.: : ::.: .  .  .
XP_006                    MNVDLLSCALWSGAFSEVVLAEEKATGKLFAVKCIPKKALK
                                  10        20        30        40 

               110       120       130       140       150         
pF1KE0 GREACV-SELSVLRRVSHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERD
       :.:. . .:..:::...:. :: : .:.:. ...:.::.:..:::::::.. .: .::.:
XP_006 GKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKD
              50        60        70        80        90       100 

     160       170       180       190       200        210        
pF1KE0 AVRILQMVADGIRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLA-YSGKKSGDWT
       :  ....: :.. ::: . :.::.:::::::::   :::::.:.::::. . ::  :: .
XP_006 ASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGK--GD-V
             110       120       130       140       150           

      220       230       240       250       260       270        
pF1KE0 MKTLCGTPEYIAPEVLLRKPYTSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGK
       :.: :::: :.::::: .:::..::: :..:::.: :: :. :: ::....:...:::..
XP_006 MSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAE
      160       170       180       190       200       210        

      280       290       300       310       320         330      
pF1KE0 YNYTGEPWPSISHLAKDFIDKLLILEAGHRMSAGQALDHPWVITMAAGSSM--KNLQRAI
       :.. .  : .::  ::::: .:.  . ..:..  ::  :::.    ::..   ::.....
XP_006 YEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI----AGDTALNKNIHESV
      220       230       240       250       260           270    

        340       350       360       370       380                
pF1KE0 SRNLMQRASPHSQSPGSAQSSKSHYSHKSRHMWSKRNLRIVESPLSALL           
       :                                                           
XP_006 SAQIRKNFAKSKWRQAFNATAVVRHMRKLHLGSSLDSSNASVSSSLSLASQKDCLAPSTL
          280       290       300       310       320       330    




385 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov 18 17:34:52 2016 done: Fri Nov 18 17:34:53 2016
 Total Scan time:  8.760 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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