Result of FASTA (omim) for pF1KE2379
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE2379, 1159 aa
  1>>>pF1KE2379 1159 - 1159 aa - 1159 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.4530+/-0.000378; mu= 5.0542+/- 0.024
 mean_var=251.0289+/-51.872, 0's: 0 Z-trim(121.3): 88  B-trim: 1574 in 1/58
 Lambda= 0.080949
 statistics sampled from 37684 (37772) to 37684 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.746), E-opt: 0.2 (0.443), width:  16
 Scan time: 16.540

The best scores are:                                      opt bits E(85289)
NP_000229 (OMIM: 152427,609620,613688) potassium v (1159) 7844 930.0       0
XP_016867685 (OMIM: 152427,609620,613688) PREDICTE (1100) 7434 882.1       0
XP_011514487 (OMIM: 152427,609620,613688) PREDICTE (1059) 7140 847.8       0
XP_016867684 (OMIM: 152427,609620,613688) PREDICTE (1109) 7140 847.8       0
XP_011514488 (OMIM: 152427,609620,613688) PREDICTE ( 910) 6027 717.8 7.7e-206
NP_742053 (OMIM: 152427,609620,613688) potassium v ( 888) 5358 639.6 2.5e-182
NP_742054 (OMIM: 152427,609620,613688) potassium v ( 819) 5337 637.1 1.3e-181
XP_016860709 (OMIM: 608169) PREDICTED: potassium v (1189) 3984 479.3 6.3e-134
NP_150375 (OMIM: 608169) potassium voltage-gated c (1196) 3836 462.0  1e-128
XP_016860708 (OMIM: 608169) PREDICTED: potassium v (1193) 3805 458.4 1.2e-127
XP_016860707 (OMIM: 608169) PREDICTED: potassium v (1201) 3748 451.7 1.2e-125
XP_011510411 (OMIM: 608169) PREDICTED: potassium v (1204) 3124 378.8 1.1e-103
XP_011523610 (OMIM: 608168) PREDICTED: potassium v ( 918) 3078 373.4 3.6e-102
XP_011523611 (OMIM: 608168) PREDICTED: potassium v ( 915) 3077 373.3 3.9e-102
XP_016880669 (OMIM: 608168) PREDICTED: potassium v ( 871) 3076 373.1 4.1e-102
NP_110406 (OMIM: 608168) potassium voltage-gated c ( 994) 3076 373.2 4.6e-102
XP_016880664 (OMIM: 608168) PREDICTED: potassium v ( 994) 3076 373.2 4.6e-102
XP_016880665 (OMIM: 608168) PREDICTED: potassium v ( 983) 3048 369.9 4.4e-101
NP_001265849 (OMIM: 608168) potassium voltage-gate ( 835) 3031 367.9 1.5e-100
XP_016880666 (OMIM: 608168) PREDICTED: potassium v ( 958) 3031 367.9 1.7e-100
NP_001265848 (OMIM: 608168) potassium voltage-gate ( 958) 3031 367.9 1.7e-100
XP_016880667 (OMIM: 608168) PREDICTED: potassium v ( 947) 3030 367.8 1.8e-100
XP_011523613 (OMIM: 608168) PREDICTED: potassium v ( 726) 3010 365.4 7.5e-100
XP_011523614 (OMIM: 608168) PREDICTED: potassium v ( 726) 3010 365.4 7.5e-100
NP_775185 (OMIM: 608169) potassium voltage-gated c ( 732) 2954 358.8   7e-98
XP_011523615 (OMIM: 608168) PREDICTED: potassium v ( 711) 2951 358.5 8.7e-98
NP_001191727 (OMIM: 152427,609620,613688) potassiu ( 548) 2851 346.7 2.3e-94
XP_016860710 (OMIM: 608169) PREDICTED: potassium v ( 661) 1812 225.4 9.1e-58
NP_653234 (OMIM: 608260) potassium voltage-gated c (1107) 1627 204.0 4.3e-51
XP_016861188 (OMIM: 608260) PREDICTED: potassium v (1030) 1613 202.3 1.3e-50
XP_016861187 (OMIM: 608260) PREDICTED: potassium v (1108) 1613 202.3 1.3e-50
XP_016861190 (OMIM: 608260) PREDICTED: potassium v ( 930) 1605 201.4 2.2e-50
XP_016880668 (OMIM: 608168) PREDICTED: potassium v ( 941) 1543 194.1 3.4e-48
XP_011523612 (OMIM: 608168) PREDICTED: potassium v ( 905) 1498 188.8 1.3e-46
NP_775115 (OMIM: 608168) potassium voltage-gated c ( 905) 1498 188.8 1.3e-46
XP_016879891 (OMIM: 604528) PREDICTED: potassium v ( 957) 1442 182.3 1.2e-44
XP_016879890 (OMIM: 604528) PREDICTED: potassium v ( 968) 1442 182.3 1.2e-44
XP_016879889 (OMIM: 604528) PREDICTED: potassium v (1017) 1442 182.3 1.3e-44
NP_036417 (OMIM: 604528) potassium voltage-gated c (1017) 1442 182.3 1.3e-44
XP_016879892 (OMIM: 604528) PREDICTED: potassium v ( 532) 1119 144.4 1.8e-33
NP_002229 (OMIM: 135500,603305,611816) potassium v ( 962) 1118 144.5   3e-33
NP_647479 (OMIM: 605716) potassium voltage-gated c ( 988) 1086 140.8 4.1e-32
XP_016861189 (OMIM: 608260) PREDICTED: potassium v ( 986) 1027 133.9 4.9e-30
XP_016874586 (OMIM: 604527) PREDICTED: potassium v ( 720)  986 129.0 1.1e-28
NP_001300959 (OMIM: 604527) potassium voltage-gate (1023)  986 129.1 1.4e-28
NP_036416 (OMIM: 604527) potassium voltage-gated c (1083)  986 129.1 1.5e-28
XP_016874585 (OMIM: 604527) PREDICTED: potassium v (1016)  974 127.7 3.7e-28
XP_011536388 (OMIM: 604527) PREDICTED: potassium v (1034)  974 127.7 3.7e-28
XP_011536387 (OMIM: 604527) PREDICTED: potassium v (1094)  974 127.7 3.9e-28
XP_016856735 (OMIM: 135500,603305,611816) PREDICTE ( 597)  943 123.9   3e-27


>>NP_000229 (OMIM: 152427,609620,613688) potassium volta  (1159 aa)
 initn: 7844 init1: 7844 opt: 7844  Z-score: 4961.9  bits: 930.0 E(85289):    0
Smith-Waterman score: 7844; 100.0% identity (100.0% similar) in 1159 aa overlap (1-1159:1-1159)

               10        20        30        40        50        60
pF1KE2 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 QRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 AVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 RSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 PRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 RHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE2 PKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIY
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE2 TAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE2 EVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLD
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE2 RYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSS
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE2 GLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVS
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE2 AIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGF
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE2 PECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALY
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KE2 FISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLE
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KE2 VLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTE
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KE2 QPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSS
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KE2 PRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTP
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KE2 SLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSA
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KE2 VTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPG
             1090      1100      1110      1120      1130      1140

             1150         
pF1KE2 QLGALTSQPLHRHGSDPGS
       :::::::::::::::::::
NP_000 QLGALTSQPLHRHGSDPGS
             1150         

>>XP_016867685 (OMIM: 152427,609620,613688) PREDICTED: p  (1100 aa)
 initn: 7434 init1: 7434 opt: 7434  Z-score: 4703.4  bits: 882.1 E(85289):    0
Smith-Waterman score: 7434; 100.0% identity (100.0% similar) in 1100 aa overlap (60-1159:1-1100)

      30        40        50        60        70        80         
pF1KE2 IIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGA
                                     ::::::::::::::::::::::::::::::
XP_016                               MQRPCTCDFLHGPRTQRRAAAQIAQALLGA
                                             10        20        30

      90       100       110       120       130       140         
pF1KE2 EERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRG
               40        50        60        70        80        90

     150       160       170       180       190       200         
pF1KE2 PPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSES
              100       110       120       130       140       150

     210       220       230       240       250       260         
pF1KE2 LALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLAR
              160       170       180       190       200       210

     270       280       290       300       310       320         
pF1KE2 TRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRT
              220       230       240       250       260       270

     330       340       350       360       370       380         
pF1KE2 ISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYK
              280       290       300       310       320       330

     390       400       410       420       430       440         
pF1KE2 LQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYAC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYAC
              340       350       360       370       380       390

     450       460       470       480       490       500         
pF1KE2 QPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFD
              400       410       420       430       440       450

     510       520       530       540       550       560         
pF1KE2 LLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWY
              460       470       480       490       500       510

     570       580       590       600       610       620         
pF1KE2 AIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGN
              520       530       540       550       560       570

     630       640       650       660       670       680         
pF1KE2 VSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQI
              580       590       600       610       620       630

     690       700       710       720       730       740         
pF1KE2 PNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKG
              640       650       660       670       680       690

     750       760       770       780       790       800         
pF1KE2 CLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPL
              700       710       720       730       740       750

     810       820       830       840       850       860         
pF1KE2 NLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIP
              760       770       780       790       800       810

     870       880       890       900       910       920         
pF1KE2 GSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGE
              820       830       840       850       860       870

     930       940       950       960       970       980         
pF1KE2 SPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSG
              880       890       900       910       920       930

     990      1000      1010      1020      1030      1040         
pF1KE2 AFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQL
              940       950       960       970       980       990

    1050      1060      1070      1080      1090      1100         
pF1KE2 NRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLS
             1000      1010      1020      1030      1040      1050

    1110      1120      1130      1140      1150         
pF1KE2 QVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS
             1060      1070      1080      1090      1100

>>XP_011514487 (OMIM: 152427,609620,613688) PREDICTED: p  (1059 aa)
 initn: 7140 init1: 7140 opt: 7140  Z-score: 4518.1  bits: 847.8 E(85289):    0
Smith-Waterman score: 7140; 100.0% identity (100.0% similar) in 1057 aa overlap (103-1159:3-1059)

             80        90       100       110       120       130  
pF1KE2 RTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVV
                                     ::::::::::::::::::::::::::::::
XP_011                             MAGSCFLCLVDVVPVKNEDGAVIMFILNFEVV
                                           10        20        30  

            140       150       160       170       180       190  
pF1KE2 MEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPG
             40        50        60        70        80        90  

            200       210       220       230       240       250  
pF1KE2 AVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPR
            100       110       120       130       140       150  

            260       270       280       290       300       310  
pF1KE2 AHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLR
            160       170       180       190       200       210  

            320       330       340       350       360       370  
pF1KE2 SGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTE
            220       230       240       250       260       270  

            380       390       400       410       420       430  
pF1KE2 KVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFL
            280       290       300       310       320       330  

            440       450       460       470       480       490  
pF1KE2 LKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVH
            340       350       360       370       380       390  

            500       510       520       530       540       550  
pF1KE2 YFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFL
            400       410       420       430       440       450  

            560       570       580       590       600       610  
pF1KE2 LMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYV
            460       470       480       490       500       510  

            620       630       640       650       660       670  
pF1KE2 TALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTAR
            520       530       540       550       560       570  

            680       690       700       710       720       730  
pF1KE2 YHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHL
            580       590       600       610       620       630  

            740       750       760       770       780       790  
pF1KE2 NRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRG
            640       650       660       670       680       690  

            800       810       820       830       840       850  
pF1KE2 DVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHF
            700       710       720       730       740       750  

            860       870       880       890       900       910  
pF1KE2 WSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGR
            760       770       780       790       800       810  

            920       930       940       950       960       970  
pF1KE2 AGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEP
            820       830       840       850       860       870  

            980       990      1000      1010      1020      1030  
pF1KE2 LMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGR
            880       890       900       910       920       930  

           1040      1050      1060      1070      1080      1090  
pF1KE2 RPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTS
            940       950       960       970       980       990  

           1100      1110      1120      1130      1140      1150  
pF1KE2 PLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHR
           1000      1010      1020      1030      1040      1050  

              
pF1KE2 HGSDPGS
       :::::::
XP_011 HGSDPGS
              

>>XP_016867684 (OMIM: 152427,609620,613688) PREDICTED: p  (1109 aa)
 initn: 7140 init1: 7140 opt: 7140  Z-score: 4517.8  bits: 847.8 E(85289):    0
Smith-Waterman score: 7140; 100.0% identity (100.0% similar) in 1057 aa overlap (103-1159:53-1109)

             80        90       100       110       120       130  
pF1KE2 RTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVV
                                     ::::::::::::::::::::::::::::::
XP_016 VRGQEWLLQGDPDRAPELRALGRGCEGLGCGSCFLCLVDVVPVKNEDGAVIMFILNFEVV
             30        40        50        60        70        80  

            140       150       160       170       180       190  
pF1KE2 MEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPG
             90       100       110       120       130       140  

            200       210       220       230       240       250  
pF1KE2 AVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPR
            150       160       170       180       190       200  

            260       270       280       290       300       310  
pF1KE2 AHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLR
            210       220       230       240       250       260  

            320       330       340       350       360       370  
pF1KE2 SGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTE
            270       280       290       300       310       320  

            380       390       400       410       420       430  
pF1KE2 KVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFL
            330       340       350       360       370       380  

            440       450       460       470       480       490  
pF1KE2 LKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVH
            390       400       410       420       430       440  

            500       510       520       530       540       550  
pF1KE2 YFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFL
            450       460       470       480       490       500  

            560       570       580       590       600       610  
pF1KE2 LMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYV
            510       520       530       540       550       560  

            620       630       640       650       660       670  
pF1KE2 TALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTAR
            570       580       590       600       610       620  

            680       690       700       710       720       730  
pF1KE2 YHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHL
            630       640       650       660       670       680  

            740       750       760       770       780       790  
pF1KE2 NRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRG
            690       700       710       720       730       740  

            800       810       820       830       840       850  
pF1KE2 DVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHF
            750       760       770       780       790       800  

            860       870       880       890       900       910  
pF1KE2 WSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGR
            810       820       830       840       850       860  

            920       930       940       950       960       970  
pF1KE2 AGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEP
            870       880       890       900       910       920  

            980       990      1000      1010      1020      1030  
pF1KE2 LMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGR
            930       940       950       960       970       980  

           1040      1050      1060      1070      1080      1090  
pF1KE2 RPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTS
            990      1000      1010      1020      1030      1040  

           1100      1110      1120      1130      1140      1150  
pF1KE2 PLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHR
           1050      1060      1070      1080      1090      1100  

              
pF1KE2 HGSDPGS
       :::::::
XP_016 HGSDPGS
              

>>XP_011514488 (OMIM: 152427,609620,613688) PREDICTED: p  (910 aa)
 initn: 6024 init1: 6024 opt: 6027  Z-score: 3816.5  bits: 717.8 E(85289): 7.7e-206
Smith-Waterman score: 6027; 99.6% identity (99.6% similar) in 902 aa overlap (1-902:1-902)

               10        20        30        40        50        60
pF1KE2 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 QRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 AVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 RSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 PRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 RHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE2 PKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIY
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE2 TAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE2 EVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLD
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE2 RYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSS
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE2 GLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVS
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE2 AIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGF
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE2 PECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALY
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KE2 FISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLE
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KE2 VLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTE
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::   
XP_011 VLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKAPG
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KE2 QPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSS
        :                                                          
XP_011 PPESRRVGSP                                                  
              910                                                  

>>NP_742053 (OMIM: 152427,609620,613688) potassium volta  (888 aa)
 initn: 5358 init1: 5358 opt: 5358  Z-score: 3394.4  bits: 639.6 E(85289): 2.5e-182
Smith-Waterman score: 5358; 100.0% identity (100.0% similar) in 800 aa overlap (1-800:1-800)

               10        20        30        40        50        60
pF1KE2 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 QRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 QRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 AVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 AVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 RSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 RSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 PRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 PRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 RHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 RHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE2 PKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 PKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIY
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE2 TAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 TAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE2 EVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 EVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLD
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE2 RYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 RYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSS
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE2 GLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 GLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVS
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE2 AIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 AIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGF
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE2 PECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 PECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALY
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KE2 FISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLE
       ::::::::::::::::::::                                        
NP_742 FISRGSIEILRGDVVVAILGMGWGAGTGLEMPSAASRGASLLNMQSLGLWTWDCLQGHWA
              790       800       810       820       830       840

>>NP_742054 (OMIM: 152427,609620,613688) potassium volta  (819 aa)
 initn: 5335 init1: 5335 opt: 5337  Z-score: 3381.6  bits: 637.1 E(85289): 1.3e-181
Smith-Waterman score: 5337; 98.9% identity (99.4% similar) in 795 aa overlap (366-1159:25-819)

         340       350       360       370        380       390    
pF1KE2 ITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQ-VLSLGADVLPEYKLQAPR
                                     :.  ..  :.: ::::::::::::::::::
NP_742       MAAPAGKASRTGALRPRAQKGRVRRAVRISSLVAQEVLSLGADVLPEYKLQAPR
                     10        20        30        40        50    

          400       410       420       430       440       450    
pF1KE2 IHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 IHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAV
           60        70        80        90       100       110    

          460       470       480       490       500       510    
pF1KE2 VDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 VDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFG
          120       130       140       150       160       170    

          520       530       540       550       560       570    
pF1KE2 SGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 SGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNM
          180       190       200       210       220       230    

          580       590       600       610       620       630    
pF1KE2 EQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 EQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNT
          240       250       260       270       280       290    

          640       650       660       670       680       690    
pF1KE2 NSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 NSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLR
          300       310       320       330       340       350    

          700       710       720       730       740       750    
pF1KE2 QRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 QRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRAL
          360       370       380       390       400       410    

          760       770       780       790       800       810    
pF1KE2 AMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 AMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYAR
          420       430       440       450       460       470    

          820       830       840       850       860       870    
pF1KE2 PGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 PGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGS
          480       490       500       510       520       530    

          880       890       900       910       920       930    
pF1KE2 TELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 TELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSG
          540       550       560       570       580       590    

          940       950       960       970       980       990    
pF1KE2 PSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 PSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGV
          600       610       620       630       640       650    

         1000      1010      1020      1030      1040      1050    
pF1KE2 SNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 SNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLET
          660       670       680       690       700       710    

         1060      1070      1080      1090      1100      1110    
pF1KE2 RLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 RLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQF
          720       730       740       750       760       770    

         1120      1130      1140      1150         
pF1KE2 MACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS
       :::::::::::::::::::::::::::::::::::::::::::::
NP_742 MACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS
          780       790       800       810         

>>XP_016860709 (OMIM: 608169) PREDICTED: potassium volta  (1189 aa)
 initn: 3272 init1: 1599 opt: 3984  Z-score: 2525.4  bits: 479.3 E(85289): 6.3e-134
Smith-Waterman score: 4185; 60.8% identity (77.5% similar) in 1149 aa overlap (1-1120:1-1105)

               10        20        30        40        50        60
pF1KE2 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVM
       ::::::::::::::: :::::::::..:::::::::.:::.:::::::::. :.:: .::
XP_016 MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 QRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDG
       :.::::::::::.:.:.  :::::::::.::::::...:.:.:: :.: . ..::::..:
XP_016 QKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 AVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSV
       ...:::.::: : ... ...:     .:  :   .     : : .:.:.: .:: :..:.
XP_016 VAMMFIINFEYVTDNENAATP-----ERVNPILPIKTVNRKFFGFKFPGLRVLTYRKQSL
              130       140            150       160       170     

              190       200       210       220       230          
pF1KE2 RSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPG--
        .        : .::.:     .  :..:.:. .  .  ..  . . :.. .::. :.  
XP_016 PQED------PDVVVID----SSKHSDDSVAMKHFKSPTKESCSPSEADDTKALIQPSKC
               180           190       200       210       220     

      240         250         260       270       280       290    
pF1KE2 SPPRSAPGQLP--SPRAH--SLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAG
       ::  .  : :   ::. .   : ::   :: .:...:::::  :.:::::. :::..  :
XP_016 SPLVNISGPLDHSSPKRQWDRLYPDMLQSSSQLSHSRSRESLCSIRRASSVHDIEGF--G
         230       240       250       260       270       280     

             300       310       320       330       340       350 
pF1KE2 VLPPP---PRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLAS
       : :      :::: : .. ..:.::.:::::.: .: ::.::::.:::: ..: .   .:
XP_016 VHPKNIFRDRHASEGPFNHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSEVKTEKKNSS
           290       300       310       320       330       340   

              360       370       380       390       400       410
pF1KE2 P-TSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVW
       : .::. :::::.:.::::::::::::::::::::::::::.:::...::::::::::::
XP_016 PPSSDKTIIAPKVKDRTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVW
           350       360       370       380       390       400   

              420       430       440       450       460       470
pF1KE2 DWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILIN
       ::::::::::::.::::::::::.. ::     ::::.:.:: :::::::::::.:::::
XP_016 DWLILLLVIYTAIFTPYSAAFLLNDREE-QKRRECGYSCSPLNVVDLIVDIMFIIDILIN
           410       420       430        440       450       460  

              480       490       500       510          520       
pF1KE2 FRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEE---LIGLLKTA
       ::::::: :::::: :..::.::::::::::::::::::::::::::.:   ::::::::
XP_016 FRTTYVNQNEEVVSDPAKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSDETTTLIGLLKTA
            470       480       490       500       510       520  

       530       540       550       560       570       580       
pF1KE2 RLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLH
       :::::::::::::::::::::::.:::: :::::::::::::::::.:.:.. ..:::: 
XP_016 RLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVERPYLTDKIGWLD
            530       540       550       560       570       580  

       590       600        610       620       630       640      
pF1KE2 NLGDQIGKPYNSS-GLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVML
       .::.:::: ::.: . .:::::::::::::::::::::::::::::::::::::::::::
XP_016 SLGQQIGKRYNDSDSSSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVML
            590       600       610       620       630       640  

        650       660       670       680       690       700      
pF1KE2 IGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWS
       :::::::::::::::::::::::::::: :::::.::::::::::::::::::::::::.
XP_016 IGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWT
            650       660       670       680       690       700  

        710       720       730       740       750       760      
pF1KE2 YTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPG
       :::::::: ::::::::::::::::::..:::.:: ::::.:::::::::::::::::::
XP_016 YTNGIDMNMVLKGFPECLQADICLHLNQTLLQNCKAFRGASKGCLRALAMKFKTTHAPPG
            710       720       730       740       750       760  

        770       780       790       800       810       820      
pF1KE2 DTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALT
       ::::: ::.::::::.::::::::. :.::::::::::::: ..:::.:::::.::::::
XP_016 DTLVHCGDVLTALYFLSRGSIEILKDDIVVAILGKNDIFGEMVHLYAKPGKSNADVRALT
            770       780       790       800       810       820  

        830       840       850       860       870          880   
pF1KE2 YCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPG---SPGSTELEGGFSR
       :::::::.:.:::::::::::::::: ..::.:::::  .       : . .. ::   .
XP_016 YCDLHKIQREDLLEVLDMYPEFSDHFLTNLELTFNLRHESAKADLLRSQSMNDSEGDNCK
            830       840       850       860       870       880  

           890         900       910       920       930       940 
pF1KE2 QRKRKLSFRRRTDKD--TEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESS
        :.:::::. . .:.  :..: : ::          ::. .    . :. : . :   : 
XP_016 LRRRKLSFESEGEKENSTNDP-EDSA---DTIRHYQSSKRH----FEEKKSRSSSFISSI
            890       900           910           920       930    

             950       960        970       980       990      1000
pF1KE2 EDEGPGRSSSPLRLVPFSSPRPPGEPPG-GEPLMEDCEKSSDTCNPLSGAFSGVSNIFSF
       .::     ..::    ::.    .  :: :.    : :..     : :: .   .   : 
XP_016 DDE-----QKPL----FSGIVDSS--PGIGKASGLDFEETV----PTSGRMHIDKRSHSC
               940             950       960           970         

             1010         1020          1030      1040      1050   
pF1KE2 WGDSRGRQYQELPRCPAP---TPSLLNIPL----SSPGRRPRGDVESRLDALQRQLNRLE
          .  :....    : :   .:: :.        . .    :.::.::: ::.::::::
XP_016 KDITDMRSWERENAHPQPEDSSPSALQRAAWGISETESDLTYGEVEQRLDLLQEQLNRLE
     980       990      1000      1010      1020      1030         

          1060      1070      1080      1090       1100       1110 
pF1KE2 TRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVS-PLPTLTLD-SLSQV
       .....:. :.:::::.: :.:::::: ::. .        :. .: :  ..  : :.:  
XP_016 SQMTTDIQTILQLLQKQTTVVPPAYSMVTAGSEYQRPIIQLMRTSQPEASIKTDRSFSPS
    1040      1050      1060      1070      1080      1090         

            1120      1130      1140      1150                     
pF1KE2 SQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS            
       ::   : :.                                                   
XP_016 SQ---CPEFLDLEKSKLKSKESLSSGVHLNTASEDNLTSLLKQDSDLSLELHLRQRKTYV
    1100         1110      1120      1130      1140      1150      

>>NP_150375 (OMIM: 608169) potassium voltage-gated chann  (1196 aa)
 initn: 2938 init1: 1599 opt: 3836  Z-score: 2432.0  bits: 462.0 E(85289): 1e-128
Smith-Waterman score: 4161; 60.5% identity (77.0% similar) in 1156 aa overlap (1-1120:1-1112)

               10        20        30        40        50        60
pF1KE2 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVM
       ::::::::::::::: :::::::::..:::::::::.:::.:::::::::. :.:: .::
NP_150 MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 QRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDG
       :.::::::::::.:.:.  :::::::::.::::::...:.:.:: :.: . ..::::..:
NP_150 QKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 AVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSV
       ...:::.::: : ... ...:     .:  :   .     : : .:.:.: .:: :..:.
NP_150 VAMMFIINFEYVTDNENAATP-----ERVNPILPIKTVNRKFFGFKFPGLRVLTYRKQSL
              130       140            150       160       170     

              190       200       210       220       230          
pF1KE2 RSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPG--
        .        : .::.:     .  :..:.:. .  .  ..  . . :.. .::. :.  
NP_150 PQED------PDVVVID----SSKHSDDSVAMKHFKSPTKESCSPSEADDTKALIQPSKC
               180           190       200       210       220     

      240         250         260       270       280       290    
pF1KE2 SPPRSAPGQLP--SPRAH--SLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAG
       ::  .  : :   ::. .   : ::   :: .:...:::::  :.:::::. :::..  :
NP_150 SPLVNISGPLDHSSPKRQWDRLYPDMLQSSSQLSHSRSRESLCSIRRASSVHDIEGF--G
         230       240       250       260       270       280     

             300              310       320       330       340    
pF1KE2 VLPPP---PRHAST-------GAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLK
       : :      ::::        : .. ..:.::.:::::.: .: ::.::::.:::: ..:
NP_150 VHPKNIFRDRHASEDNGRNVKGPFNHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSEVK
           290       300       310       320       330       340   

          350        360       370       380       390       400   
pF1KE2 GDPFLASP-TSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHY
        .   .:: .::. :::::.:.::::::::::::::::::::::::::.:::...:::::
NP_150 TEKKNSSPPSSDKTIIAPKVKDRTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHY
           350       360       370       380       390       400   

           410       420       430       440       450       460   
pF1KE2 SPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMF
       :::::::::::::::::::.::::::::::.. ::     ::::.:.:: ::::::::::
NP_150 SPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDREE-QKRRECGYSCSPLNVVDLIVDIMF
           410       420       430        440       450       460  

           470       480       490       500       510          520
pF1KE2 IVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEE---L
       :.:::::::::::: :::::: :..::.::::::::::::::::::::::::::.:   :
NP_150 IIDILINFRTTYVNQNEEVVSDPAKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSDETTTL
            470       480       490       500       510       520  

              530       540       550       560       570       580
pF1KE2 IGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMD
       ::::::::::::::::::::::::::::::.:::: :::::::::::::::::.:.:.. 
NP_150 IGLLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVERPYLT
            530       540       550       560       570       580  

              590       600        610       620       630         
pF1KE2 SRIGWLHNLGDQIGKPYNSS-GLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKI
       ..:::: .::.:::: ::.: . .::::::::::::::::::::::::::::::::::::
NP_150 DKIGWLDSLGQQIGKRYNDSDSSSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKI
            590       600       610       620       630       640  

     640       650       660       670       680       690         
pF1KE2 FSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEE
       ::::::::::::::::::::::::::::::::::: :::::.::::::::::::::::::
NP_150 FSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEE
            650       660       670       680       690       700  

     700       710       720       730       740       750         
pF1KE2 YFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFK
       ::::::.:::::::: ::::::::::::::::::..:::.:: ::::.::::::::::::
NP_150 YFQHAWTYTNGIDMNMVLKGFPECLQADICLHLNQTLLQNCKAFRGASKGCLRALAMKFK
            710       720       730       740       750       760  

     760       770       780       790       800       810         
pF1KE2 TTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSN
       :::::::::::: ::.::::::.::::::::. :.::::::::::::: ..:::.:::::
NP_150 TTHAPPGDTLVHCGDVLTALYFLSRGSIEILKDDIVVAILGKNDIFGEMVHLYAKPGKSN
            770       780       790       800       810       820  

     820       830       840       850       860       870         
pF1KE2 GDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPG---SPGSTE
       .:::::::::::::.:.:::::::::::::::: ..::.:::::  .       : . ..
NP_150 ADVRALTYCDLHKIQREDLLEVLDMYPEFSDHFLTNLELTFNLRHESAKADLLRSQSMND
            830       840       850       860       870       880  

        880       890         900       910       920       930    
pF1KE2 LEGGFSRQRKRKLSFRRRTDKD--TEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSG
        ::   . :.:::::. . .:.  :..: : ::          ::. .    . :. : .
NP_150 SEGDNCKLRRRKLSFESEGEKENSTNDP-EDSA---DTIRHYQSSKRH----FEEKKSRS
            890       900       910           920           930    

          940       950       960        970       980       990   
pF1KE2 PSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPG-GEPLMEDCEKSSDTCNPLSGAFSG
        :   : .::     ..::    ::.    .  :: :.    : :..     : :: .  
NP_150 SSFISSIDDE-----QKPL----FSGIVDSS--PGIGKASGLDFEETV----PTSGRMHI
          940                950         960       970             

          1000      1010         1020          1030      1040      
pF1KE2 VSNIFSFWGDSRGRQYQELPRCPAP---TPSLLNIPL----SSPGRRPRGDVESRLDALQ
        .   :    .  :....    : :   .:: :.        . .    :.::.::: ::
NP_150 DKRSHSCKDITDMRSWERENAHPQPEDSSPSALQRAAWGISETESDLTYGEVEQRLDLLQ
     980       990      1000      1010      1020      1030         

       1050      1060      1070      1080      1090       1100     
pF1KE2 RQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVS-PLPTLTL
       .::::::.....:. :.:::::.: :.:::::: ::. .        :. .: :  ..  
NP_150 EQLNRLESQMTTDIQTILQLLQKQTTVVPPAYSMVTAGSEYQRPIIQLMRTSQPEASIKT
    1040      1050      1060      1070      1080      1090         

         1110      1120      1130      1140      1150              
pF1KE2 D-SLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS     
       : :.:  ::   : :.                                            
NP_150 DRSFSPSSQ---CPEFLDLEKSKLKSKESLSSGVHLNTASEDNLTSLLKQDSDLSLELHL
    1100         1110      1120      1130      1140      1150      

>>XP_016860708 (OMIM: 608169) PREDICTED: potassium volta  (1193 aa)
 initn: 1866 init1: 1625 opt: 3805  Z-score: 2412.4  bits: 458.4 E(85289): 1.2e-127
Smith-Waterman score: 4129; 60.2% identity (76.7% similar) in 1156 aa overlap (1-1120:1-1109)

               10        20        30        40        50        60
pF1KE2 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVM
       ::::::::::::::: :::::::::..:::::::::.:::.:::::::::. :.:: .::
XP_016 MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 QRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDG
       :.::::::::::.:.:.  :::::::::.::::::...:.:.:: :.: . ..::::..:
XP_016 QKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 AVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSV
       ...:::.::: : ... ...:     .:  :   .     : : .:.:.: .:: :..:.
XP_016 VAMMFIINFEYVTDNENAATP-----ERVNPILPIKTVNRKFFGFKFPGLRVLTYRKQSL
              130       140            150       160       170     

              190       200       210       220       230          
pF1KE2 RSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPG--
        .        : .::.:     .  :..:.:. .  .  ..  . . :.. .::. :.  
XP_016 PQED------PDVVVID----SSKHSDDSVAMKHFKSPTKESCSPSEADDTKALIQPSKC
               180           190       200       210       220     

      240         250         260       270       280       290    
pF1KE2 SPPRSAPGQLP--SPRAH--SLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAG
       ::  .  : :   ::. .   : ::   :: .:...:::::  :.:::::. :::..  :
XP_016 SPLVNISGPLDHSSPKRQWDRLYPDMLQSSSQLSHSRSRESLCSIRRASSVHDIEGF--G
         230       240       250       260       270       280     

             300              310       320       330       340    
pF1KE2 VLPPP---PRHAST-------GAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLK
       : :      ::::        : .. ..:.::.:::::.: .: ::.::::.:::: ..:
XP_016 VHPKNIFRDRHASEDNGRNVKGPFNHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSEVK
           290       300       310       320       330       340   

          350        360       370       380       390       400   
pF1KE2 GDPFLASP-TSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHY
        .   .:: .::. :::::.:.::::::::::::::::::::::::::.:::...:::::
XP_016 TEKKNSSPPSSDKTIIAPKVKDRTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHY
           350       360       370       380       390       400   

           410       420       430       440       450       460   
pF1KE2 SPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMF
       :::::::::::::::::::.::::::::::.. ::     ::::.:.:: ::::::::::
XP_016 SPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDREE-QKRRECGYSCSPLNVVDLIVDIMF
           410       420       430        440       450       460  

           470       480       490       500       510          520
pF1KE2 IVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEE---L
       :.:::::::::::: :::::: :..::.::::::::::::::::::::::::::.:   :
XP_016 IIDILINFRTTYVNQNEEVVSDPAKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSDETTTL
            470       480       490       500       510       520  

              530       540       550       560       570       580
pF1KE2 IGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMD
       ::::::::::::::::::::::::::::::.:::: :::::::::::::::::.:.:.. 
XP_016 IGLLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVERPYLT
            530       540       550       560       570       580  

              590       600        610       620       630         
pF1KE2 SRIGWLHNLGDQIGKPYNSS-GLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKI
       ..:::: .::.:::: ::.: . .::::::::::::::::::::::::::::::::::::
XP_016 DKIGWLDSLGQQIGKRYNDSDSSSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKI
            590       600       610       620       630       640  

     640       650       660       670       680       690         
pF1KE2 FSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEE
       ::::::::::::::::::::::::::::::::::: :::::.::::::::::::::::::
XP_016 FSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEE
            650       660       670       680       690       700  

     700       710       720       730       740       750         
pF1KE2 YFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFK
       ::::::.::::::::    :::::::::::::::..:::.:: ::::.::::::::::::
XP_016 YFQHAWTYTNGIDMNM---GFPECLQADICLHLNQTLLQNCKAFRGASKGCLRALAMKFK
            710          720       730       740       750         

     760       770       780       790       800       810         
pF1KE2 TTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSN
       :::::::::::: ::.::::::.::::::::. :.::::::::::::: ..:::.:::::
XP_016 TTHAPPGDTLVHCGDVLTALYFLSRGSIEILKDDIVVAILGKNDIFGEMVHLYAKPGKSN
     760       770       780       790       800       810         

     820       830       840       850       860       870         
pF1KE2 GDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPG---SPGSTE
       .:::::::::::::.:.:::::::::::::::: ..::.:::::  .       : . ..
XP_016 ADVRALTYCDLHKIQREDLLEVLDMYPEFSDHFLTNLELTFNLRHESAKADLLRSQSMND
     820       830       840       850       860       870         

        880       890         900       910       920       930    
pF1KE2 LEGGFSRQRKRKLSFRRRTDKD--TEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSG
        ::   . :.:::::. . .:.  :..: : ::          ::. .    . :. : .
XP_016 SEGDNCKLRRRKLSFESEGEKENSTNDP-EDSA---DTIRHYQSSKRH----FEEKKSRS
     880       890       900        910          920           930 

          940       950       960        970       980       990   
pF1KE2 PSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPG-GEPLMEDCEKSSDTCNPLSGAFSG
        :   : .::     ..::    ::.    .  :: :.    : :..     : :: .  
XP_016 SSFISSIDDE-----QKPL----FSGIVDSS--PGIGKASGLDFEETV----PTSGRMHI
             940                950         960           970      

          1000      1010         1020          1030      1040      
pF1KE2 VSNIFSFWGDSRGRQYQELPRCPAP---TPSLLNIPL----SSPGRRPRGDVESRLDALQ
        .   :    .  :....    : :   .:: :.        . .    :.::.::: ::
XP_016 DKRSHSCKDITDMRSWERENAHPQPEDSSPSALQRAAWGISETESDLTYGEVEQRLDLLQ
        980       990      1000      1010      1020      1030      

       1050      1060      1070      1080      1090       1100     
pF1KE2 RQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVS-PLPTLTL
       .::::::.....:. :.:::::.: :.:::::: ::. .        :. .: :  ..  
XP_016 EQLNRLESQMTTDIQTILQLLQKQTTVVPPAYSMVTAGSEYQRPIIQLMRTSQPEASIKT
       1040      1050      1060      1070      1080      1090      

         1110      1120      1130      1140      1150              
pF1KE2 D-SLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS     
       : :.:  ::   : :.                                            
XP_016 DRSFSPSSQ---CPEFLDLEKSKLKSKESLSSGVHLNTASEDNLTSLLKQDSDLSLELHL
       1100         1110      1120      1130      1140      1150   




1159 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 16:14:20 2016 done: Sun Nov  6 16:14:22 2016
 Total Scan time: 16.540 Total Display time:  0.320

Function used was FASTA [36.3.4 Apr, 2011]
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