Result of FASTA (omim) for pF1KE9573
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE9573, 474 aa
  1>>>pF1KE9573     474 - 474 aa - 474 aa
Library: /omim/omim.rfq.tfa
  64942286 residues in 91783 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.6080+/-0.000402; mu= 15.8301+/- 0.025
 mean_var=67.9529+/-14.298, 0's: 0 Z-trim(111.5): 308  B-trim: 876 in 1/48
 Lambda= 0.155586
 statistics sampled from 20615 (20935) to 20615 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.583), E-opt: 0.2 (0.228), width:  16
 Scan time:  3.750

The best scores are:                                      opt bits E(91783)
NP_001158210 (OMIM: 114131,166710) calcitonin rece ( 474) 3309 752.2 7.7e-217
NP_001733 (OMIM: 114131,166710) calcitonin recepto ( 474) 3309 752.2 7.7e-217
NP_001158209 (OMIM: 114131,166710) calcitonin rece ( 490) 2048 469.1 1.3e-131
NP_001258680 (OMIM: 114190) calcitonin gene-relate ( 461) 1872 429.6 9.4e-120
NP_005786 (OMIM: 114190) calcitonin gene-related p ( 461) 1872 429.6 9.4e-120
XP_005246291 (OMIM: 114190) calcitonin gene-relate ( 472) 1872 429.6 9.6e-120
XP_005246289 (OMIM: 114190) calcitonin gene-relate ( 472) 1872 429.6 9.6e-120
XP_005246288 (OMIM: 114190) calcitonin gene-relate ( 472) 1872 429.6 9.6e-120
XP_016858640 (OMIM: 114190) calcitonin gene-relate ( 472) 1872 429.6 9.6e-120
NP_001189404 (OMIM: 602034) corticotropin-releasin ( 438)  784 185.4 2.9e-46
NP_001874 (OMIM: 602034) corticotropin-releasing f ( 411)  772 182.7 1.8e-45
XP_024302433 (OMIM: 602034) corticotropin-releasin ( 411)  772 182.7 1.8e-45
NP_001189410 (OMIM: 602034) corticotropin-releasin ( 397)  771 182.5   2e-45
XP_016867241 (OMIM: 602034) corticotropin-releasin ( 397)  771 182.5   2e-45
XP_005265494 (OMIM: 192321) vasoactive intestinal  ( 456)  770 182.3 2.7e-45
NP_001189411 (OMIM: 602034) corticotropin-releasin ( 410)  767 181.6 3.9e-45
NP_001238814 (OMIM: 192321) vasoactive intestinal  ( 430)  766 181.4 4.8e-45
NP_004615 (OMIM: 192321) vasoactive intestinal pol ( 457)  766 181.4   5e-45
XP_005265495 (OMIM: 192321) vasoactive intestinal  ( 416)  764 180.9 6.3e-45
NP_001238811 (OMIM: 192321) vasoactive intestinal  ( 416)  764 180.9 6.3e-45
XP_011532381 (OMIM: 192321) vasoactive intestinal  ( 416)  764 180.9 6.3e-45
NP_001238813 (OMIM: 192321) vasoactive intestinal  ( 409)  757 179.3 1.9e-44
XP_005265496 (OMIM: 192321) vasoactive intestinal  ( 410)  753 178.4 3.5e-44
NP_001189412 (OMIM: 602034) corticotropin-releasin ( 387)  748 177.3 7.2e-44
NP_001186566 (OMIM: 102981) pituitary adenylate cy ( 447)  745 176.6 1.3e-43
NP_004373 (OMIM: 122561) corticotropin-releasing f ( 415)  716 170.1 1.1e-41
NP_002971 (OMIM: 182098) secretin receptor precurs ( 440)  684 163.0 1.7e-39
XP_016860159 (OMIM: 182098) secretin receptor isof ( 435)  669 159.6 1.7e-38
XP_011509923 (OMIM: 182098) secretin receptor isof ( 445)  669 159.6 1.8e-38
XP_024308806 (OMIM: 182098) secretin receptor isof ( 372)  667 159.1 2.1e-38
NP_001138619 (OMIM: 122561) corticotropin-releasin ( 375)  652 155.7 2.1e-37
XP_016860161 (OMIM: 182098) secretin receptor isof ( 377)  652 155.7 2.1e-37
XP_005249675 (OMIM: 102981) pituitary adenylate cy ( 411)  645 154.2 6.9e-37
NP_001109 (OMIM: 102981) pituitary adenylate cycla ( 468)  645 154.2 7.7e-37
NP_001289949 (OMIM: 122561) corticotropin-releasin ( 314)  632 151.2 4.1e-36
NP_000155 (OMIM: 137241) gastric inhibitory polype ( 466)  629 150.6 9.3e-36
XP_016860160 (OMIM: 182098) secretin receptor isof ( 409)  608 145.9 2.2e-34
NP_000814 (OMIM: 139191,612781) growth hormone-rel ( 423)  606 145.4   3e-34
NP_001138620 (OMIM: 122561) corticotropin-releasin ( 401)  600 144.1 7.4e-34
NP_003373 (OMIM: 601970) vasoactive intestinal pol ( 438)  600 144.1   8e-34
XP_005249618 (OMIM: 601970) vasoactive intestinal  ( 463)  600 144.1 8.4e-34
NP_001138618 (OMIM: 122561) corticotropin-releasin ( 444)  571 137.6 7.4e-32
XP_006716170 (OMIM: 601970) vasoactive intestinal  ( 455)  570 137.4 8.8e-32
XP_005265401 (OMIM: 125350,156400,168468,215045,60 ( 562)  570 137.4 1.1e-31
XP_016862422 (OMIM: 125350,156400,168468,215045,60 ( 593)  570 137.4 1.1e-31
NP_000307 (OMIM: 125350,156400,168468,215045,60000 ( 593)  570 137.4 1.1e-31
NP_001171673 (OMIM: 125350,156400,168468,215045,60 ( 593)  570 137.4 1.1e-31
XP_011532270 (OMIM: 125350,156400,168468,215045,60 ( 600)  570 137.4 1.1e-31
XP_016862421 (OMIM: 125350,156400,168468,215045,60 ( 606)  570 137.4 1.1e-31
XP_011532269 (OMIM: 125350,156400,168468,215045,60 ( 606)  570 137.4 1.1e-31


>>NP_001158210 (OMIM: 114131,166710) calcitonin receptor  (474 aa)
 initn: 3309 init1: 3309 opt: 3309  Z-score: 4014.5  bits: 752.2 E(91783): 7.7e-217
Smith-Waterman score: 3309; 100.0% identity (100.0% similar) in 474 aa overlap (1-474:1-474)

               10        20        30        40        50        60
pF1KE9 MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYVVGRKKMMDAQYKCYDRMQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYVVGRKKMMDAQYKCYDRMQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 QLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 HPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE9 VTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE9 GIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHLLYI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHLLYI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE9 IHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFVVFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFVVFP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE9 WRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRWGRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRWGRR
              370       380       390       400       410       420

              430       440       450       460       470    
pF1KE9 PSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIPLNIIEQESSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIPLNIIEQESSA
              430       440       450       460       470    

>>NP_001733 (OMIM: 114131,166710) calcitonin receptor is  (474 aa)
 initn: 3309 init1: 3309 opt: 3309  Z-score: 4014.5  bits: 752.2 E(91783): 7.7e-217
Smith-Waterman score: 3309; 100.0% identity (100.0% similar) in 474 aa overlap (1-474:1-474)

               10        20        30        40        50        60
pF1KE9 MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYVVGRKKMMDAQYKCYDRMQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYVVGRKKMMDAQYKCYDRMQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 QLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 HPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE9 VTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE9 GIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHLLYI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHLLYI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE9 IHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFVVFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFVVFP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE9 WRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRWGRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRWGRR
              370       380       390       400       410       420

              430       440       450       460       470    
pF1KE9 PSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIPLNIIEQESSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIPLNIIEQESSA
              430       440       450       460       470    

>>NP_001158209 (OMIM: 114131,166710) calcitonin receptor  (490 aa)
 initn: 2048 init1: 2048 opt: 2048  Z-score: 2484.6  bits: 469.1 E(91783): 1.3e-131
Smith-Waterman score: 3267; 96.7% identity (96.7% similar) in 490 aa overlap (1-474:1-490)

               10        20        30        40        50        60
pF1KE9 MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYVVGRKKMMDAQYKCYDRMQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYVVGRKKMMDAQYKCYDRMQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 QLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFK
               70        80        90       100       110       120

              130       140       150       160       170          
pF1KE9 HPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFR------
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::      
NP_001 HPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRKLTTIF
              130       140       150       160       170       180

                    180       190       200       210       220    
pF1KE9 ----------SLGCQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHF
                 ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLNWKYRKALSLGCQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHF
              190       200       210       220       230       240

          230       240       250       260       270       280    
pF1KE9 FHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVY
              250       260       270       280       290       300

          290       300       310       320       330       340    
pF1KE9 FNDNCWLSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNDNCWLSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKA
              310       320       330       340       350       360

          350       360       370       380       390       400    
pF1KE9 TMILVPLLGIQFVVFPWRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TMILVPLLGIQFVVFPWRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKR
              370       380       390       400       410       420

          410       420       430       440       450       460    
pF1KE9 QWAQFKIQWNQRWGRRPSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QWAQFKIQWNQRWGRRPSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIP
              430       440       450       460       470       480

          470    
pF1KE9 LNIIEQESSA
       ::::::::::
NP_001 LNIIEQESSA
              490

>>NP_001258680 (OMIM: 114190) calcitonin gene-related pe  (461 aa)
 initn: 1851 init1: 1851 opt: 1872  Z-score: 2271.5  bits: 429.6 E(91783): 9.4e-120
Smith-Waterman score: 1872; 57.8% identity (81.6% similar) in 445 aa overlap (8-449:4-442)

               10        20        30        40           50       
pF1KE9 MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYV---VGRKKMMDAQYKCYD
              .:   ::.:      :: :   .   .: .:   .   : :.:.: :::.::.
NP_001     MEKKCTLYFLVL------LPFFMILVTAELEESPEDSIQLGVTRNKIMTAQYECYQ
                   10              20        30        40        50

        60        70        80        90       100       110       
pF1KE9 RMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGV
       ...: :  :.:: ::::::::::::.:. ::. :.:.::::: :::::::::: ::. : 
NP_001 KIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGN
               60        70        80        90       100       110

       120       130       140       150       160       170       
pF1KE9 WFKHPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLG
       ::.:: .::::.:::.::. : ::.:.:  :.::.:.::.::: .:.:::::: .:.::.
NP_001 WFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLS
              120       130       140       150       160       170

       180       190       200       210       220       230       
pF1KE9 CQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWM
       :::.:::::.:.... ::.. ::::. :. :  ::  .:::::. .:.: :.:.::::::
NP_001 CQRITLHKNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWM
              180       190       200       210       220       230

       240       250       260       270       280       290       
pF1KE9 LCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHL
       ::::::::::::::::.:::.: :::.:::::::.:. ::::.:..:.:::::.: .:::
NP_001 LCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTHL
              240       250       260       270       280       290

       300       310       320       330       340       350       
pF1KE9 LYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFV
       :::::::. :::.::.::::::::::.::.. ::.:::..:.:::.::.::::::::.::
NP_001 LYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFV
              300       310       320       330       340       350

       360       370       380       390       400       410       
pF1KE9 VFPWRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRW
       ..:::: .:.  ..:::.:: :.::::..:.::.:: :.:::. ..:.: :.:::... .
NP_001 LIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNSF
              360       370       380       390       400       410

       420       430       440       450       460       470    
pF1KE9 GRRPSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIPLNIIEQESSA
       .   . :::  ....   :    . : .:  :                         
NP_001 SNSEALRSASYTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN      
              420       430       440       450       460       

>>NP_005786 (OMIM: 114190) calcitonin gene-related pepti  (461 aa)
 initn: 1851 init1: 1851 opt: 1872  Z-score: 2271.5  bits: 429.6 E(91783): 9.4e-120
Smith-Waterman score: 1872; 57.8% identity (81.6% similar) in 445 aa overlap (8-449:4-442)

               10        20        30        40           50       
pF1KE9 MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYV---VGRKKMMDAQYKCYD
              .:   ::.:      :: :   .   .: .:   .   : :.:.: :::.::.
NP_005     MEKKCTLYFLVL------LPFFMILVTAELEESPEDSIQLGVTRNKIMTAQYECYQ
                   10              20        30        40        50

        60        70        80        90       100       110       
pF1KE9 RMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGV
       ...: :  :.:: ::::::::::::.:. ::. :.:.::::: :::::::::: ::. : 
NP_005 KIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGN
               60        70        80        90       100       110

       120       130       140       150       160       170       
pF1KE9 WFKHPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLG
       ::.:: .::::.:::.::. : ::.:.:  :.::.:.::.::: .:.:::::: .:.::.
NP_005 WFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLS
              120       130       140       150       160       170

       180       190       200       210       220       230       
pF1KE9 CQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWM
       :::.:::::.:.... ::.. ::::. :. :  ::  .:::::. .:.: :.:.::::::
NP_005 CQRITLHKNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWM
              180       190       200       210       220       230

       240       250       260       270       280       290       
pF1KE9 LCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHL
       ::::::::::::::::.:::.: :::.:::::::.:. ::::.:..:.:::::.: .:::
NP_005 LCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTHL
              240       250       260       270       280       290

       300       310       320       330       340       350       
pF1KE9 LYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFV
       :::::::. :::.::.::::::::::.::.. ::.:::..:.:::.::.::::::::.::
NP_005 LYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFV
              300       310       320       330       340       350

       360       370       380       390       400       410       
pF1KE9 VFPWRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRW
       ..:::: .:.  ..:::.:: :.::::..:.::.:: :.:::. ..:.: :.:::... .
NP_005 LIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNSF
              360       370       380       390       400       410

       420       430       440       450       460       470    
pF1KE9 GRRPSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIPLNIIEQESSA
       .   . :::  ....   :    . : .:  :                         
NP_005 SNSEALRSASYTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN      
              420       430       440       450       460       

>>XP_005246291 (OMIM: 114190) calcitonin gene-related pe  (472 aa)
 initn: 1851 init1: 1851 opt: 1872  Z-score: 2271.4  bits: 429.6 E(91783): 9.6e-120
Smith-Waterman score: 1872; 57.8% identity (81.6% similar) in 445 aa overlap (8-449:15-453)

                      10        20        30        40           50
pF1KE9        MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYV---VGRKKMMD
                     .:   ::.:      :: :   .   .: .:   .   : :.:.: 
XP_005 MLYSIFHFGLMMEKKCTLYFLVL------LPFFMILVTAELEESPEDSIQLGVTRNKIMT
               10        20              30        40        50    

               60        70        80        90       100       110
pF1KE9 AQYKCYDRMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTK
       :::.::....: :  :.:: ::::::::::::.:. ::. :.:.::::: ::::::::::
XP_005 AQYECYQKIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTK
           60        70        80        90       100       110    

              120       130       140       150       160       170
pF1KE9 YCDEKGVWFKHPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIF
        ::. : ::.:: .::::.:::.::. : ::.:.:  :.::.:.::.::: .:.::::::
XP_005 ICDQDGNWFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIF
          120       130       140       150       160       170    

              180       190       200       210       220       230
pF1KE9 VFFRSLGCQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMM
        .:.::.:::.:::::.:.... ::.. ::::. :. :  ::  .:::::. .:.: :.:
XP_005 FYFKSLSCQRITLHKNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLM
          180       190       200       210       220       230    

              240       250       260       270       280       290
pF1KE9 ACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCW
       .::::::::::::::::::::::.:::.: :::.:::::::.:. ::::.:..:.:::::
XP_005 GCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCW
          240       250       260       270       280       290    

              300       310       320       330       340       350
pF1KE9 LSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVP
       .: .::::::::::. :::.::.::::::::::.::.. ::.:::..:.:::.::.::::
XP_005 ISSDTHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVP
          300       310       320       330       340       350    

              360       370       380       390       400       410
pF1KE9 LLGIQFVVFPWRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFK
       ::::.::..:::: .:.  ..:::.:: :.::::..:.::.:: :.:::. ..:.: :.:
XP_005 LLGIEFVLIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYK
          360       370       380       390       400       410    

              420       430       440       450       460       470
pF1KE9 IQWNQRWGRRPSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIPLNIIEQ
       ::... ..   . :::  ....   :    . : .:  :                     
XP_005 IQFGNSFSNSEALRSASYTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN  
          420       430       440       450       460       470    

           
pF1KE9 ESSA

>>XP_005246289 (OMIM: 114190) calcitonin gene-related pe  (472 aa)
 initn: 1851 init1: 1851 opt: 1872  Z-score: 2271.4  bits: 429.6 E(91783): 9.6e-120
Smith-Waterman score: 1872; 57.8% identity (81.6% similar) in 445 aa overlap (8-449:15-453)

                      10        20        30        40           50
pF1KE9        MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYV---VGRKKMMD
                     .:   ::.:      :: :   .   .: .:   .   : :.:.: 
XP_005 MLYSIFHFGLMMEKKCTLYFLVL------LPFFMILVTAELEESPEDSIQLGVTRNKIMT
               10        20              30        40        50    

               60        70        80        90       100       110
pF1KE9 AQYKCYDRMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTK
       :::.::....: :  :.:: ::::::::::::.:. ::. :.:.::::: ::::::::::
XP_005 AQYECYQKIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTK
           60        70        80        90       100       110    

              120       130       140       150       160       170
pF1KE9 YCDEKGVWFKHPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIF
        ::. : ::.:: .::::.:::.::. : ::.:.:  :.::.:.::.::: .:.::::::
XP_005 ICDQDGNWFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIF
          120       130       140       150       160       170    

              180       190       200       210       220       230
pF1KE9 VFFRSLGCQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMM
        .:.::.:::.:::::.:.... ::.. ::::. :. :  ::  .:::::. .:.: :.:
XP_005 FYFKSLSCQRITLHKNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLM
          180       190       200       210       220       230    

              240       250       260       270       280       290
pF1KE9 ACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCW
       .::::::::::::::::::::::.:::.: :::.:::::::.:. ::::.:..:.:::::
XP_005 GCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCW
          240       250       260       270       280       290    

              300       310       320       330       340       350
pF1KE9 LSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVP
       .: .::::::::::. :::.::.::::::::::.::.. ::.:::..:.:::.::.::::
XP_005 ISSDTHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVP
          300       310       320       330       340       350    

              360       370       380       390       400       410
pF1KE9 LLGIQFVVFPWRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFK
       ::::.::..:::: .:.  ..:::.:: :.::::..:.::.:: :.:::. ..:.: :.:
XP_005 LLGIEFVLIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYK
          360       370       380       390       400       410    

              420       430       440       450       460       470
pF1KE9 IQWNQRWGRRPSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIPLNIIEQ
       ::... ..   . :::  ....   :    . : .:  :                     
XP_005 IQFGNSFSNSEALRSASYTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN  
          420       430       440       450       460       470    

           
pF1KE9 ESSA

>>XP_005246288 (OMIM: 114190) calcitonin gene-related pe  (472 aa)
 initn: 1851 init1: 1851 opt: 1872  Z-score: 2271.4  bits: 429.6 E(91783): 9.6e-120
Smith-Waterman score: 1872; 57.8% identity (81.6% similar) in 445 aa overlap (8-449:15-453)

                      10        20        30        40           50
pF1KE9        MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYV---VGRKKMMD
                     .:   ::.:      :: :   .   .: .:   .   : :.:.: 
XP_005 MLYSIFHFGLMMEKKCTLYFLVL------LPFFMILVTAELEESPEDSIQLGVTRNKIMT
               10        20              30        40        50    

               60        70        80        90       100       110
pF1KE9 AQYKCYDRMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTK
       :::.::....: :  :.:: ::::::::::::.:. ::. :.:.::::: ::::::::::
XP_005 AQYECYQKIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTK
           60        70        80        90       100       110    

              120       130       140       150       160       170
pF1KE9 YCDEKGVWFKHPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIF
        ::. : ::.:: .::::.:::.::. : ::.:.:  :.::.:.::.::: .:.::::::
XP_005 ICDQDGNWFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIF
          120       130       140       150       160       170    

              180       190       200       210       220       230
pF1KE9 VFFRSLGCQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMM
        .:.::.:::.:::::.:.... ::.. ::::. :. :  ::  .:::::. .:.: :.:
XP_005 FYFKSLSCQRITLHKNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLM
          180       190       200       210       220       230    

              240       250       260       270       280       290
pF1KE9 ACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCW
       .::::::::::::::::::::::.:::.: :::.:::::::.:. ::::.:..:.:::::
XP_005 GCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCW
          240       250       260       270       280       290    

              300       310       320       330       340       350
pF1KE9 LSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVP
       .: .::::::::::. :::.::.::::::::::.::.. ::.:::..:.:::.::.::::
XP_005 ISSDTHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVP
          300       310       320       330       340       350    

              360       370       380       390       400       410
pF1KE9 LLGIQFVVFPWRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFK
       ::::.::..:::: .:.  ..:::.:: :.::::..:.::.:: :.:::. ..:.: :.:
XP_005 LLGIEFVLIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYK
          360       370       380       390       400       410    

              420       430       440       450       460       470
pF1KE9 IQWNQRWGRRPSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIPLNIIEQ
       ::... ..   . :::  ....   :    . : .:  :                     
XP_005 IQFGNSFSNSEALRSASYTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN  
          420       430       440       450       460       470    

           
pF1KE9 ESSA

>>XP_016858640 (OMIM: 114190) calcitonin gene-related pe  (472 aa)
 initn: 1851 init1: 1851 opt: 1872  Z-score: 2271.4  bits: 429.6 E(91783): 9.6e-120
Smith-Waterman score: 1872; 57.8% identity (81.6% similar) in 445 aa overlap (8-449:15-453)

                      10        20        30        40           50
pF1KE9        MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYV---VGRKKMMD
                     .:   ::.:      :: :   .   .: .:   .   : :.:.: 
XP_016 MLYSIFHFGLMMEKKCTLYFLVL------LPFFMILVTAELEESPEDSIQLGVTRNKIMT
               10        20              30        40        50    

               60        70        80        90       100       110
pF1KE9 AQYKCYDRMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTK
       :::.::....: :  :.:: ::::::::::::.:. ::. :.:.::::: ::::::::::
XP_016 AQYECYQKIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTK
           60        70        80        90       100       110    

              120       130       140       150       160       170
pF1KE9 YCDEKGVWFKHPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIF
        ::. : ::.:: .::::.:::.::. : ::.:.:  :.::.:.::.::: .:.::::::
XP_016 ICDQDGNWFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIF
          120       130       140       150       160       170    

              180       190       200       210       220       230
pF1KE9 VFFRSLGCQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMM
        .:.::.:::.:::::.:.... ::.. ::::. :. :  ::  .:::::. .:.: :.:
XP_016 FYFKSLSCQRITLHKNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLM
          180       190       200       210       220       230    

              240       250       260       270       280       290
pF1KE9 ACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCW
       .::::::::::::::::::::::.:::.: :::.:::::::.:. ::::.:..:.:::::
XP_016 GCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCW
          240       250       260       270       280       290    

              300       310       320       330       340       350
pF1KE9 LSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVP
       .: .::::::::::. :::.::.::::::::::.::.. ::.:::..:.:::.::.::::
XP_016 ISSDTHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVP
          300       310       320       330       340       350    

              360       370       380       390       400       410
pF1KE9 LLGIQFVVFPWRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFK
       ::::.::..:::: .:.  ..:::.:: :.::::..:.::.:: :.:::. ..:.: :.:
XP_016 LLGIEFVLIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYK
          360       370       380       390       400       410    

              420       430       440       450       460       470
pF1KE9 IQWNQRWGRRPSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIPLNIIEQ
       ::... ..   . :::  ....   :    . : .:  :                     
XP_016 IQFGNSFSNSEALRSASYTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN  
          420       430       440       450       460       470    

           
pF1KE9 ESSA

>>NP_001189404 (OMIM: 602034) corticotropin-releasing fa  (438 aa)
 initn: 661 init1: 227 opt: 784  Z-score: 952.0  bits: 185.4 E(91783): 2.9e-46
Smith-Waterman score: 787; 33.0% identity (62.2% similar) in 436 aa overlap (36-452:25-437)

          10        20        30        40                50       
pF1KE9 TSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYVVGRKKM--------MDAQYKCYD
                                     : :. :..:...:        .  :: :. 
NP_001       MRGPSGPPGLLYVPHLLLCLLCLLPPPLQYAAGQSQMPKDQPLWALLEQY-CHT
                     10        20        30        40        50    

        60        70         80        90       100         110    
pF1KE9 RMQQLPAYQGEGPYCNRTWDGW-LCWDDTPAGVLSYQFCPDYFPD--FDPSEKVTKYCDE
        :  :   .:   ::: : :    ::  . ::.:  . ::.::    .. .... . : :
NP_001 IMT-LTNLSGPYSYCNTTLDQIGTCWPRSAAGALVERPCPEYFNGVKYNTTRNAYRECLE
             60        70        80        90       100       110  

          120       130       140       150           160       170
pF1KE9 KGVWFKHPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIV----GHSLSIFTLVISLGIF
       .:.:        .  ::..:. .  .: ..  . : .:.:    :: .:. .:: .. .:
NP_001 NGTW-------ASKINYSQCEPILDDKQRKYDLHYRIALVVNYLGHCVSVAALVAAFLLF
                   120       130       140       150       160     

              180       190        200       210       220         
pF1KE9 VFFRSLGCQRVTLHKNMFLTYIL-NSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYM
       . .::. : : ..: :.. :.:: : : ....::.     :. . . : :. .  . .:.
NP_001 LALRSIRCLRNVIHWNLITTFILRNVMWFLLQLVD----HEVHESNEVWCRCITTIFNYF
         170       180       190       200           210       220 

     230       240       250       260       270       280         
pF1KE9 MACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNC
       .. :.:::. :: :::: ::..  ::. :   . ..:: .:.   .  :: .  : :..:
NP_001 VVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIVAWAIGKLYYENEQC
             230       240       250       260       270       280 

     290         300       310       320       330       340       
pF1KE9 WLSVETHLL--YIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMI
       :.. :   :  :: .::.. .:..:: ::.::::.:.::.: .  .:. .: ::::::..
NP_001 WFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTSETIQYRKAVKATLV
             290       300       310       320       330       340 

       350       360       370       380        390       400      
pF1KE9 LVPLLGIQFVVFPWRPSNKMLGKIYDYVMHSLIH-FQGFFVATIYCFCNNEVQTTVKRQW
       :.::::: ...:   :..  :..:.   ..:... ::::::...::: :.::...:...:
NP_001 LLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYCFFNGEVRSAVRKRW
             350       360       370       380       390       400 

        410       420       430       440       450       460      
pF1KE9 AQFKIQWNQRWGRRPSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIPLN
               .::  . : :   : : .  ..  :  :  . ...  :              
NP_001 --------HRWQDHHSLRVPMARAMSIPTS--PTRISFHSIKQTAAV             
                     410       420         430                     

        470    
pF1KE9 IIEQESSA




474 residues in 1 query   sequences
64942286 residues in 91783 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Sep 11 18:47:00 2018 done: Tue Sep 11 18:47:01 2018
 Total Scan time:  3.750 Total Display time:  0.100

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com