Result of FASTA (omim) for pF1KE1218
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1218, 213 aa
  1>>>pF1KE1218     213 - 213 aa - 213 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.4782+/-0.000352; mu= 1.0783+/- 0.022
 mean_var=205.0416+/-40.915, 0's: 0 Z-trim(120.9): 35  B-trim: 152 in 1/58
 Lambda= 0.089568
 statistics sampled from 36769 (36806) to 36769 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.732), E-opt: 0.2 (0.432), width:  16
 Scan time:  6.280

The best scores are:                                      opt bits E(85289)
NP_005310 (OMIM: 142710) histone H1.2 [Homo sapien ( 213) 1308 180.5 1.8e-45
NP_005312 (OMIM: 142220) histone H1.4 [Homo sapien ( 219) 1106 154.4 1.3e-37
NP_005311 (OMIM: 142210) histone H1.3 [Homo sapien ( 221) 1053 147.6 1.5e-35
NP_005313 (OMIM: 142711) histone H1.5 [Homo sapien ( 226)  978 137.9 1.3e-32
NP_005316 (OMIM: 142709) histone H1.1 [Homo sapien ( 215)  799 114.8 1.1e-25
NP_005314 (OMIM: 142712) histone H1t [Homo sapiens ( 207)  524 79.2 5.4e-15
NP_005309 (OMIM: 142708) histone H1.0 [Homo sapien ( 194)  373 59.7 3.8e-09
NP_006017 (OMIM: 602785) histone H1x [Homo sapiens ( 213)  335 54.8 1.2e-07


>>NP_005310 (OMIM: 142710) histone H1.2 [Homo sapiens]    (213 aa)
 initn: 1308 init1: 1308 opt: 1308  Z-score: 937.5  bits: 180.5 E(85289): 1.8e-45
Smith-Waterman score: 1308; 100.0% identity (100.0% similar) in 213 aa overlap (1-213:1-213)

               10        20        30        40        50        60
pF1KE1 MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 ALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 KKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVA
              130       140       150       160       170       180

              190       200       210   
pF1KE1 KPKKAAKSAAKAVKPKAAKPKVVKPKKAAPKKK
       :::::::::::::::::::::::::::::::::
NP_005 KPKKAAKSAAKAVKPKAAKPKVVKPKKAAPKKK
              190       200       210   

>>NP_005312 (OMIM: 142220) histone H1.4 [Homo sapiens]    (219 aa)
 initn: 931 init1: 931 opt: 1106  Z-score: 796.3  bits: 154.4 E(85289): 1.3e-37
Smith-Waterman score: 1106; 86.9% identity (93.9% similar) in 214 aa overlap (1-212:1-213)

               10        20        30        40        50        60
pF1KE1 MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLA
       :::::::::::  ::::.:::::: :.::.. ::::::::::::::::::::::::::::
NP_005 MSETAPAAPAAPAPAEKTPVKKKARKSAGAAKRKASGPPVSELITKAVAASKERSGVSLA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 ALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKV
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_005 ALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 KKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVA
       ::::..: :::.:::::::::.:.::::::::::::::::::::. .:: ::::::::.:
NP_005 KKAGAAKAKKPAGAAKKPKKATGAATPKKSAKKTPKKAKKPAAAAGAKK-AKSPKKAKAA
              130       140       150       160        170         

              190         200       210        
pF1KE1 KPKKAAKSAAKA--VKPKAAKPKVVKPKKAAPKKK     
       ::::: :: :::  :::::::::..::: : :::      
NP_005 KPKKAPKSPAKAKAVKPKAAKPKTAKPKAAKPKKAAAKKK
     180       190       200       210         

>>NP_005311 (OMIM: 142210) histone H1.3 [Homo sapiens]    (221 aa)
 initn: 1231 init1: 882 opt: 1053  Z-score: 759.2  bits: 147.6 E(85289): 1.5e-35
Smith-Waterman score: 1053; 81.1% identity (90.5% similar) in 222 aa overlap (1-213:1-221)

               10        20        30          40        50        
pF1KE1 MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTP--RKASGPPVSELITKAVAASKERSGVS
       :::::: ::.   ::::.:::::: ::::.:   ::::::::::::::::::::::::::
NP_005 MSETAPLAPTIPAPAEKTPVKKKA-KKAGATAGKRKASGPPVSELITKAVAASKERSGVS
               10        20         30        40        50         

       60        70        80        90       100       110        
pF1KE1 LAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKP
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::
NP_005 LAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEGKP
      60        70        80        90       100       110         

      120       130       140       150       160       170        
pF1KE1 KVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAK
       :.::::..::.::.::::::::.::.:::::: ::::::.::::.:. ::::::: ::.:
NP_005 KAKKAGAAKPRKPAGAAKKPKKVAGAATPKKSIKKTPKKVKKPATAAGTKKVAKSAKKVK
     120       130       140       150       160       170         

      180       190              200       210   
pF1KE1 VAKPKKAAKSAAKA-------VKPKAAKPKVVKPKKAAPKKK
       . .::::::: :::       .:::..::::.: ::::::::
NP_005 TPQPKKAAKSPAKAKAPKPKAAKPKSGKPKVTKAKKAAPKKK
     180       190       200       210       220 

>>NP_005313 (OMIM: 142711) histone H1.5 [Homo sapiens]    (226 aa)
 initn: 737 init1: 737 opt: 978  Z-score: 706.7  bits: 137.9 E(85289): 1.3e-32
Smith-Waterman score: 978; 79.4% identity (89.9% similar) in 218 aa overlap (1-211:1-214)

               10        20        30           40        50       
pF1KE1 MSETAPAAPAAAPPAEKAPVKKKAAKKAGGT---PRKASGPPVSELITKAVAASKERSGV
       :::::::  :.  :.::.:.::::.:::.:.    :::.::::::::::::::::::.:.
NP_005 MSETAPAETATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGL
               10        20        30        40        50        60

        60        70        80        90       100       110       
pF1KE1 SLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK
       :::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SLAALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK
               70        80        90       100       110       120

       120       130        140       150       160       170      
pF1KE1 PKVKKAGGTKPKKPVGAA-KKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKK
       ::.::::..: :::.::. :: :::::.   ::..::::::::::::: : :::::::::
NP_005 PKAKKAGAAKAKKPAGATPKKAKKAAGA---KKAVKKTPKKAKKPAAAGV-KKVAKSPKK
              130       140          150       160        170      

        180        190         200       210             
pF1KE1 AKVA-KPKKAAKSAAK--AVKPKAAKPKVVKPKKAAPKKK          
       ::.: :::::.:: ::  ::::::::::..::: : ::            
NP_005 AKAAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK
        180       190       200       210       220      

>>NP_005316 (OMIM: 142709) histone H1.1 [Homo sapiens]    (215 aa)
 initn: 585 init1: 511 opt: 799  Z-score: 582.0  bits: 114.8 E(85289): 1.1e-25
Smith-Waterman score: 799; 67.7% identity (83.4% similar) in 223 aa overlap (1-213:1-215)

               10        20           30        40        50       
pF1KE1 MSETAPAAPAAAPPAEKAPVKKKA---AKKAGGTPRKASGPPVSELITKAVAASKERSGV
       ::::.: ::::.   ::  . :::   :: :... .: .:: :::::..:...::::.::
NP_005 MSETVPPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGV
               10        20        30        40        50        60

        60        70        80        90       100       110       
pF1KE1 SLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK
       ::::::::::::::::::::::::::.:::::::::::::::::::::::::::.: :.:
NP_005 SLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETK
               70        80        90       100       110       120

       120       130       140       150       160       170       
pF1KE1 PKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKA
       : ..:.. :: :  .::.:: :::.:..  :::.: ::::::::::   :.: .:.::: 
NP_005 PGASKVA-TKTKA-TGASKKLKKATGAS--KKSVK-TPKKAKKPAA---TRKSSKNPKKP
               130        140         150        160          170  

       180       190              200       210   
pF1KE1 KVAKPKKAAKSAAKA--VKPKAAK-----PKVVKPKKAAPKKK
       :..::::.::: :::  :::::::     ::..::::::::::
NP_005 KTVKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKKK
            180       190       200       210     

>>NP_005314 (OMIM: 142712) histone H1t [Homo sapiens]     (207 aa)
 initn: 531 init1: 379 opt: 524  Z-score: 390.2  bits: 79.2 E(85289): 5.4e-15
Smith-Waterman score: 553; 52.7% identity (73.2% similar) in 220 aa overlap (1-212:1-207)

               10          20          30        40        50      
pF1KE1 MSETAPAAPAAAPPA--EKAPVKKKAAKKAG--GTPRKASGPPVSELITKAVAASKERSG
       ::::.::: :.:  :  :: :.::.. : ::  .. ::. .  ::.:::.:...:.:: :
NP_005 MSETVPAASASAGVAAMEKLPTKKRGRKPAGLISASRKVPNLSVSKLITEALSVSQERVG
               10        20        30        40        50        60

         60        70        80        90       100       110      
pF1KE1 VSLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEA
       .::.::::::::::::::::::::::.:::::.:: ::::.::::::::::.::.    .
NP_005 MSLVALKKALAAAGYDVEKNNSRIKLSLKSLVNKGILVQTRGTGASGSFKLSKKVIPKST
               70        80        90       100       110       120

        120       130         140       150       160       170    
pF1KE1 KPKVKKAGGTKPKKPVGA--AKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSP
       . :.::. ..: :: : .  .:.:: :           :: :.:::: :.:   :...: 
NP_005 RSKAKKSVSAKTKKLVLSRDSKSPKTA-----------KTNKRAKKPRATT--PKTVRSG
              130       140                  150       160         

          180         190       200       210   
pF1KE1 KKAKVAKPKKAAKSA--AKAVKPKAAKPKVVKPKKAAPKKK
       .::: :: :.  ::   :.: : : .. . :. .::. :: 
NP_005 RKAKGAKGKQQQKSPVKARASKSKLTQHHEVNVRKATSKK 
       170       180       190       200        

>>NP_005309 (OMIM: 142708) histone H1.0 [Homo sapiens]    (194 aa)
 initn: 433 init1: 210 opt: 373  Z-score: 285.1  bits: 59.7 E(85289): 3.8e-09
Smith-Waterman score: 398; 42.4% identity (63.6% similar) in 217 aa overlap (1-213:1-189)

               10        20        30        40        50        60
pF1KE1 MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLA
       :.:.. .:::: :       . ::.::.   :.       :..:. :. : :.:.: :  
NP_005 MTENSTSAPAAKPK------RAKASKKSTDHPK------YSDMIVAAIQAEKNRAGSSRQ
               10              20              30        40        

               70         80        90       100       110         
pF1KE1 ALKKALAAAGYDVEKN-NSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPK
       ...: . .  : : .: .:.:::..: ::. :.: ::::.::::::.: :   : :  ::
NP_005 SIQKYIKSH-YKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAK---SDE--PK
       50         60        70        80        90          100    

     120       130       140       150       160          170      
pF1KE1 VKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTK---KVAKSPKK
        :...  : :: .  .  ::::.    :::.:.:.:  .::: :. : :   :.: .:::
NP_005 -KSVAFKKTKKEIKKVATPKKAS---KPKKAASKAP--TKKPKATPVKKAKKKLAATPKK
             110       120          130         140       150      

        180       190       200       210        
pF1KE1 AKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAPKKK     
       ::  ::: .  . .:: ::: :::  ::::  .  :.     
NP_005 AK--KPKTVKAKPVKASKPKKAKP--VKPKAKSSAKRAGKKK
          160       170         180       190    

>>NP_006017 (OMIM: 602785) histone H1x [Homo sapiens]     (213 aa)
 initn: 370 init1: 172 opt: 335  Z-score: 258.0  bits: 54.8 E(85289): 1.2e-07
Smith-Waterman score: 335; 37.3% identity (63.7% similar) in 204 aa overlap (5-206:18-210)

                            10        20        30        40       
pF1KE1              MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKA
                        :  .  :.  :  .: ::.  .:  . : :      :.:....
NP_006 MSVELEEALPVTTAEGMAKKVTKAGGSAALSPSKKRKNSKKKNQPGK-----YSQLVVET
               10        20        30        40             50     

        50        60         70        80        90       100      
pF1KE1 VAASKERSGVSLAAL-KKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFK
       .    ::.: ::: .  .:  .  .: ... . .: ..:.::.. ::.:.:::::.::::
NP_006 IRRLGERNGSSLAKIYTEAKKVPWFDQQNGRTYLKYSIKALVQNDTLLQVKGTGANGSFK
          60        70        80        90       100       110     

        110       120       130       140       150       160      
pF1KE1 LNKKAASGEAKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATV
       ::.:   : .. .   :..: :  :  .:.: :::: ::. .. : : : ...::   . 
NP_006 LNRKKLEGGGERRGAPAAATAPA-P--TAHKAKKAAPGAAGSRRADKKPARGQKPEQRS-
         120       130          140       150       160       170  

        170       180       190       200        210   
pF1KE1 TKKVAKSPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVK-PKKAAPKKK
        .: . . :: : .: ::.: ...: :: :::::.: : ::       
NP_006 -HKKGAGAKKDKGGKAKKTAAAGGKKVK-KAAKPSVPKVPKGRK    
              180       190        200       210       




213 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov 11 16:59:36 2016 done: Fri Nov 11 16:59:37 2016
 Total Scan time:  6.280 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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