Result of FASTA (omim) for pF1KE2049
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE2049, 671 aa
  1>>>pF1KE2049     671 - 671 aa - 671 aa
Library: /omim/omim.rfq.tfa
  64536644 residues in 91102 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 13.8161+/-0.000658; mu= -20.3536+/- 0.039
 mean_var=960.7288+/-219.771, 0's: 0 Z-trim(116.6): 224  B-trim: 1620 in 1/53
 Lambda= 0.041378
 statistics sampled from 28548 (28767) to 28548 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.656), E-opt: 0.2 (0.316), width:  16
 Scan time:  5.430

The best scores are:                                      opt bits E(91102)
NP_001341859 (OMIM: 603453) receptor-interacting s ( 671) 4511 286.4 2.5e-76
NP_003795 (OMIM: 603453) receptor-interacting seri ( 671) 4511 286.4 2.5e-76
NP_001341860 (OMIM: 603453) receptor-interacting s ( 625) 3511 226.7 2.2e-58
NP_001341861 (OMIM: 603453) receptor-interacting s ( 508) 3448 222.8 2.7e-57
XP_016866892 (OMIM: 603453) receptor-interacting s ( 508) 3448 222.8 2.7e-57
NP_001341863 (OMIM: 603453) receptor-interacting s ( 508) 3448 222.8 2.7e-57
NP_001341862 (OMIM: 603453) receptor-interacting s ( 508) 3448 222.8 2.7e-57
NP_001303990 (OMIM: 603453) receptor-interacting s ( 508) 3448 222.8 2.7e-57
XP_016866893 (OMIM: 603453) receptor-interacting s ( 382) 2485 165.1 4.6e-40
XP_006715300 (OMIM: 603453) receptor-interacting s ( 356) 2040 138.5 4.4e-32
XP_016866894 (OMIM: 603453) receptor-interacting s ( 356) 2040 138.5 4.4e-32
NP_003812 (OMIM: 603455) receptor-interacting seri ( 540)  466 44.8  0.0011


>>NP_001341859 (OMIM: 603453) receptor-interacting serin  (671 aa)
 initn: 4511 init1: 4511 opt: 4511  Z-score: 1491.9  bits: 286.4 E(91102): 2.5e-76
Smith-Waterman score: 4511; 100.0% identity (100.0% similar) in 671 aa overlap (1-671:1-671)

               10        20        30        40        50        60
pF1KE2 MQPDMSLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGPNCIEHNEAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQPDMSLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGPNCIEHNEAL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 LEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSVKGRIIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSVKGRIIL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 EIIEGMCYLHGKGVIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIIEGMCYLHGKGVIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 GTAKKNGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTAKKNGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 IKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEED
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 VKSLKKEYSNENAVVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKSLKKEYSNENAVVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE2 PSLEHPQEENEPSLQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSLEHPQEENEPSLQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPF
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE2 AQQRPYENFQNTEGKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQQRPYENFQNTEGKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLD
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE2 PGTAGPRVWYRPIPSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGTAGPRVWYRPIPSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQ
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE2 IGAYNYMEIGGTSSSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGAYNYMEIGGTSSSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKN
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE2 CARKLGFTQSQIDEIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CARKLGFTQSQIDEIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRID
              610       620       630       640       650       660

              670 
pF1KE2 LLSSLIYVSQN
       :::::::::::
NP_001 LLSSLIYVSQN
              670 

>>NP_003795 (OMIM: 603453) receptor-interacting serine/t  (671 aa)
 initn: 4511 init1: 4511 opt: 4511  Z-score: 1491.9  bits: 286.4 E(91102): 2.5e-76
Smith-Waterman score: 4511; 100.0% identity (100.0% similar) in 671 aa overlap (1-671:1-671)

               10        20        30        40        50        60
pF1KE2 MQPDMSLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGPNCIEHNEAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MQPDMSLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGPNCIEHNEAL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 LEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSVKGRIIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSVKGRIIL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 EIIEGMCYLHGKGVIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EIIEGMCYLHGKGVIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 GTAKKNGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GTAKKNGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 IKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEED
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 VKSLKKEYSNENAVVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VKSLKKEYSNENAVVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE2 PSLEHPQEENEPSLQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PSLEHPQEENEPSLQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPF
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE2 AQQRPYENFQNTEGKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AQQRPYENFQNTEGKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLD
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE2 PGTAGPRVWYRPIPSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PGTAGPRVWYRPIPSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQ
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE2 IGAYNYMEIGGTSSSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IGAYNYMEIGGTSSSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKN
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE2 CARKLGFTQSQIDEIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 CARKLGFTQSQIDEIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRID
              610       620       630       640       650       660

              670 
pF1KE2 LLSSLIYVSQN
       :::::::::::
NP_003 LLSSLIYVSQN
              670 

>>NP_001341860 (OMIM: 603453) receptor-interacting serin  (625 aa)
 initn: 3509 init1: 3509 opt: 3511  Z-score: 1169.6  bits: 226.7 E(91102): 2.2e-58
Smith-Waterman score: 4101; 93.1% identity (93.1% similar) in 671 aa overlap (1-671:1-625)

               10        20        30        40        50        60
pF1KE2 MQPDMSLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGPNCIEHNEAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQPDMSLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGPNCIEHNEAL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 LEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSVKGRIIL
       :::::::::::::::::::::::::::::::::::::::::::::::             
NP_001 LEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAE-------------
               70        80        90       100                    

              130       140       150       160       170       180
pF1KE2 EIIEGMCYLHGKGVIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVD
                                        :::::::::::::::::::::::::::
NP_001 ---------------------------------IADLGLASFKMWSKLNNEEHNELREVD
                                        110       120       130    

              190       200       210       220       230       240
pF1KE2 GTAKKNGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTAKKNGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMC
          140       150       160       170       180       190    

              250       260       270       280       290       300
pF1KE2 IKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEED
          200       210       220       230       240       250    

              310       320       330       340       350       360
pF1KE2 VKSLKKEYSNENAVVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKSLKKEYSNENAVVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFA
          260       270       280       290       300       310    

              370       380       390       400       410       420
pF1KE2 PSLEHPQEENEPSLQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSLEHPQEENEPSLQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPF
          320       330       340       350       360       370    

              430       440       450       460       470       480
pF1KE2 AQQRPYENFQNTEGKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQQRPYENFQNTEGKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLD
          380       390       400       410       420       430    

              490       500       510       520       530       540
pF1KE2 PGTAGPRVWYRPIPSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGTAGPRVWYRPIPSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQ
          440       450       460       470       480       490    

              550       560       570       580       590       600
pF1KE2 IGAYNYMEIGGTSSSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGAYNYMEIGGTSSSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKN
          500       510       520       530       540       550    

              610       620       630       640       650       660
pF1KE2 CARKLGFTQSQIDEIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CARKLGFTQSQIDEIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRID
          560       570       580       590       600       610    

              670 
pF1KE2 LLSSLIYVSQN
       :::::::::::
NP_001 LLSSLIYVSQN
          620     

>>NP_001341861 (OMIM: 603453) receptor-interacting serin  (508 aa)
 initn: 3448 init1: 3448 opt: 3448  Z-score: 1150.2  bits: 222.8 E(91102): 2.7e-57
Smith-Waterman score: 3448; 100.0% identity (100.0% similar) in 508 aa overlap (164-671:1-508)

           140       150       160       170       180       190   
pF1KE2 VIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVDGTAKKNGGTLYYM
                                     ::::::::::::::::::::::::::::::
NP_001                               MWSKLNNEEHNELREVDGTAKKNGGTLYYM
                                             10        20        30

           200       210       220       230       240       250   
pF1KE2 APEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDIT
               40        50        60        70        80        90

           260       270       280       290       300       310   
pF1KE2 EYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEEDVKSLKKEYSNENA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEEDVKSLKKEYSNENA
              100       110       120       130       140       150

           320       330       340       350       360       370   
pF1KE2 VVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFAPSLEHPQEENEPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFAPSLEHPQEENEPS
              160       170       180       190       200       210

           380       390       400       410       420       430   
pF1KE2 LQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPFAQQRPYENFQNTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPFAQQRPYENFQNTE
              220       230       240       250       260       270

           440       450       460       470       480       490   
pF1KE2 GKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLDPGTAGPRVWYRPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLDPGTAGPRVWYRPI
              280       290       300       310       320       330

           500       510       520       530       540       550   
pF1KE2 PSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQIGAYNYMEIGGTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQIGAYNYMEIGGTS
              340       350       360       370       380       390

           560       570       580       590       600       610   
pF1KE2 SSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKNCARKLGFTQSQID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKNCARKLGFTQSQID
              400       410       420       430       440       450

           620       630       640       650       660       670 
pF1KE2 EIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRIDLLSSLIYVSQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRIDLLSSLIYVSQN
              460       470       480       490       500        

>>XP_016866892 (OMIM: 603453) receptor-interacting serin  (508 aa)
 initn: 3448 init1: 3448 opt: 3448  Z-score: 1150.2  bits: 222.8 E(91102): 2.7e-57
Smith-Waterman score: 3448; 100.0% identity (100.0% similar) in 508 aa overlap (164-671:1-508)

           140       150       160       170       180       190   
pF1KE2 VIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVDGTAKKNGGTLYYM
                                     ::::::::::::::::::::::::::::::
XP_016                               MWSKLNNEEHNELREVDGTAKKNGGTLYYM
                                             10        20        30

           200       210       220       230       240       250   
pF1KE2 APEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDIT
               40        50        60        70        80        90

           260       270       280       290       300       310   
pF1KE2 EYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEEDVKSLKKEYSNENA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEEDVKSLKKEYSNENA
              100       110       120       130       140       150

           320       330       340       350       360       370   
pF1KE2 VVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFAPSLEHPQEENEPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFAPSLEHPQEENEPS
              160       170       180       190       200       210

           380       390       400       410       420       430   
pF1KE2 LQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPFAQQRPYENFQNTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPFAQQRPYENFQNTE
              220       230       240       250       260       270

           440       450       460       470       480       490   
pF1KE2 GKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLDPGTAGPRVWYRPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLDPGTAGPRVWYRPI
              280       290       300       310       320       330

           500       510       520       530       540       550   
pF1KE2 PSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQIGAYNYMEIGGTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQIGAYNYMEIGGTS
              340       350       360       370       380       390

           560       570       580       590       600       610   
pF1KE2 SSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKNCARKLGFTQSQID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKNCARKLGFTQSQID
              400       410       420       430       440       450

           620       630       640       650       660       670 
pF1KE2 EIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRIDLLSSLIYVSQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRIDLLSSLIYVSQN
              460       470       480       490       500        

>>NP_001341863 (OMIM: 603453) receptor-interacting serin  (508 aa)
 initn: 3448 init1: 3448 opt: 3448  Z-score: 1150.2  bits: 222.8 E(91102): 2.7e-57
Smith-Waterman score: 3448; 100.0% identity (100.0% similar) in 508 aa overlap (164-671:1-508)

           140       150       160       170       180       190   
pF1KE2 VIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVDGTAKKNGGTLYYM
                                     ::::::::::::::::::::::::::::::
NP_001                               MWSKLNNEEHNELREVDGTAKKNGGTLYYM
                                             10        20        30

           200       210       220       230       240       250   
pF1KE2 APEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDIT
               40        50        60        70        80        90

           260       270       280       290       300       310   
pF1KE2 EYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEEDVKSLKKEYSNENA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEEDVKSLKKEYSNENA
              100       110       120       130       140       150

           320       330       340       350       360       370   
pF1KE2 VVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFAPSLEHPQEENEPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFAPSLEHPQEENEPS
              160       170       180       190       200       210

           380       390       400       410       420       430   
pF1KE2 LQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPFAQQRPYENFQNTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPFAQQRPYENFQNTE
              220       230       240       250       260       270

           440       450       460       470       480       490   
pF1KE2 GKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLDPGTAGPRVWYRPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLDPGTAGPRVWYRPI
              280       290       300       310       320       330

           500       510       520       530       540       550   
pF1KE2 PSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQIGAYNYMEIGGTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQIGAYNYMEIGGTS
              340       350       360       370       380       390

           560       570       580       590       600       610   
pF1KE2 SSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKNCARKLGFTQSQID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKNCARKLGFTQSQID
              400       410       420       430       440       450

           620       630       640       650       660       670 
pF1KE2 EIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRIDLLSSLIYVSQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRIDLLSSLIYVSQN
              460       470       480       490       500        

>>NP_001341862 (OMIM: 603453) receptor-interacting serin  (508 aa)
 initn: 3448 init1: 3448 opt: 3448  Z-score: 1150.2  bits: 222.8 E(91102): 2.7e-57
Smith-Waterman score: 3448; 100.0% identity (100.0% similar) in 508 aa overlap (164-671:1-508)

           140       150       160       170       180       190   
pF1KE2 VIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVDGTAKKNGGTLYYM
                                     ::::::::::::::::::::::::::::::
NP_001                               MWSKLNNEEHNELREVDGTAKKNGGTLYYM
                                             10        20        30

           200       210       220       230       240       250   
pF1KE2 APEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDIT
               40        50        60        70        80        90

           260       270       280       290       300       310   
pF1KE2 EYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEEDVKSLKKEYSNENA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEEDVKSLKKEYSNENA
              100       110       120       130       140       150

           320       330       340       350       360       370   
pF1KE2 VVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFAPSLEHPQEENEPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFAPSLEHPQEENEPS
              160       170       180       190       200       210

           380       390       400       410       420       430   
pF1KE2 LQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPFAQQRPYENFQNTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPFAQQRPYENFQNTE
              220       230       240       250       260       270

           440       450       460       470       480       490   
pF1KE2 GKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLDPGTAGPRVWYRPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLDPGTAGPRVWYRPI
              280       290       300       310       320       330

           500       510       520       530       540       550   
pF1KE2 PSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQIGAYNYMEIGGTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQIGAYNYMEIGGTS
              340       350       360       370       380       390

           560       570       580       590       600       610   
pF1KE2 SSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKNCARKLGFTQSQID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKNCARKLGFTQSQID
              400       410       420       430       440       450

           620       630       640       650       660       670 
pF1KE2 EIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRIDLLSSLIYVSQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRIDLLSSLIYVSQN
              460       470       480       490       500        

>>NP_001303990 (OMIM: 603453) receptor-interacting serin  (508 aa)
 initn: 3448 init1: 3448 opt: 3448  Z-score: 1150.2  bits: 222.8 E(91102): 2.7e-57
Smith-Waterman score: 3448; 100.0% identity (100.0% similar) in 508 aa overlap (164-671:1-508)

           140       150       160       170       180       190   
pF1KE2 VIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVDGTAKKNGGTLYYM
                                     ::::::::::::::::::::::::::::::
NP_001                               MWSKLNNEEHNELREVDGTAKKNGGTLYYM
                                             10        20        30

           200       210       220       230       240       250   
pF1KE2 APEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDIT
               40        50        60        70        80        90

           260       270       280       290       300       310   
pF1KE2 EYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEEDVKSLKKEYSNENA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEEDVKSLKKEYSNENA
              100       110       120       130       140       150

           320       330       340       350       360       370   
pF1KE2 VVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFAPSLEHPQEENEPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFAPSLEHPQEENEPS
              160       170       180       190       200       210

           380       390       400       410       420       430   
pF1KE2 LQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPFAQQRPYENFQNTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPFAQQRPYENFQNTE
              220       230       240       250       260       270

           440       450       460       470       480       490   
pF1KE2 GKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLDPGTAGPRVWYRPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLDPGTAGPRVWYRPI
              280       290       300       310       320       330

           500       510       520       530       540       550   
pF1KE2 PSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQIGAYNYMEIGGTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQIGAYNYMEIGGTS
              340       350       360       370       380       390

           560       570       580       590       600       610   
pF1KE2 SSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKNCARKLGFTQSQID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKNCARKLGFTQSQID
              400       410       420       430       440       450

           620       630       640       650       660       670 
pF1KE2 EIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRIDLLSSLIYVSQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRIDLLSSLIYVSQN
              460       470       480       490       500        

>>XP_016866893 (OMIM: 603453) receptor-interacting serin  (382 aa)
 initn: 2484 init1: 2484 opt: 2485  Z-score: 840.8  bits: 165.1 E(91102): 4.6e-40
Smith-Waterman score: 2485; 97.9% identity (98.7% similar) in 376 aa overlap (296-671:7-382)

         270       280       290       300       310       320     
pF1KE2 LCWEANPEARPTFPGIEEKFRPFYLSQLEESVEEDVKSLKKEYSNENAVVKRMQSLQLDC
                                     :.   ..  :::::::::::::::::::::
XP_016                         MSSEYISIMFKINFKKKEYSNENAVVKRMQSLQLDC
                                       10        20        30      

         330       340       350       360       370       380     
pF1KE2 VAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFAPSLEHPQEENEPSLQSKLQDEANYH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFAPSLEHPQEENEPSLQSKLQDEANYH
         40        50        60        70        80        90      

         390       400       410       420       430       440     
pF1KE2 LYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPFAQQRPYENFQNTEGKGTAYSSAASH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPFAQQRPYENFQNTEGKGTAYSSAASH
        100       110       120       130       140       150      

         450       460       470       480       490       500     
pF1KE2 GNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLDPGTAGPRVWYRPIPSHMPSLHNIPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLDPGTAGPRVWYRPIPSHMPSLHNIPV
        160       170       180       190       200       210      

         510       520       530       540       550       560     
pF1KE2 PETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQIGAYNYMEIGGTSSSLLDSTNTNFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQIGAYNYMEIGGTSSSLLDSTNTNFK
        220       230       240       250       260       270      

         570       580       590       600       610       620     
pF1KE2 EEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKNCARKLGFTQSQIDEIDHDYERDGLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKNCARKLGFTQSQIDEIDHDYERDGLK
        280       290       300       310       320       330      

         630       640       650       660       670 
pF1KE2 EKVYQMLQKWVMREGIKGATVGKLAQALHQCSRIDLLSSLIYVSQN
       ::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKVYQMLQKWVMREGIKGATVGKLAQALHQCSRIDLLSSLIYVSQN
        340       350       360       370       380  

>>XP_006715300 (OMIM: 603453) receptor-interacting serin  (356 aa)
 initn: 2040 init1: 2040 opt: 2040  Z-score: 697.5  bits: 138.5 E(91102): 4.4e-32
Smith-Waterman score: 2040; 99.0% identity (99.7% similar) in 309 aa overlap (1-309:1-309)

               10        20        30        40        50        60
pF1KE2 MQPDMSLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGPNCIEHNEAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MQPDMSLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGPNCIEHNEAL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 LEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSVKGRIIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSVKGRIIL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 EIIEGMCYLHGKGVIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EIIEGMCYLHGKGVIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 GTAKKNGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GTAKKNGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 IKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEED
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 VKSLKKEYSNENAVVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFA
       :::::.: .                                                   
XP_006 VKSLKNEQTKISKDIEDRKNMTNTLDVTETQDTLHLITAAHLPAAPSNRRAPTCRT    
              310       320       330       340       350          




671 residues in 1 query   sequences
64536644 residues in 91102 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Jun  3 14:39:56 2018 done: Sun Jun  3 14:39:57 2018
 Total Scan time:  5.430 Total Display time:  0.120

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com