Result of FASTA (ccds) for pF1KE2508
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE2508, 454 aa
  1>>>pF1KE2508     454 - 454 aa - 454 aa
Library: human.CCDS.faa
  18921897 residues in 33420 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.7269+/-0.000981; mu= 7.9014+/- 0.059
 mean_var=184.2888+/-38.963, 0's: 0 Z-trim(110.3): 80  B-trim: 553 in 1/52
 Lambda= 0.094477
 statistics sampled from 11625 (11695) to 11625 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.685), E-opt: 0.2 (0.35), width:  16
 Scan time:  1.420

The best scores are:                                      opt bits E(33420)
CCDS3995.1 PIK3R1 gene_id:5295|Hs109|chr5          ( 454) 3027 425.1 7.6e-119
CCDS3993.1 PIK3R1 gene_id:5295|Hs109|chr5          ( 724) 2788 392.7 6.8e-109
CCDS3994.1 PIK3R1 gene_id:5295|Hs109|chr5          ( 424) 2771 390.1 2.3e-108
CCDS56374.1 PIK3R1 gene_id:5295|Hs109|chr5         ( 361) 2379 336.7 2.5e-92
CCDS529.1 PIK3R3 gene_id:8503|Hs109|chr1           ( 461) 2374 336.1 4.8e-92
CCDS76155.1 PIK3R3 gene_id:110117499|Hs109|chr1    ( 507) 2260 320.6 2.4e-87
CCDS12371.1 PIK3R2 gene_id:5296|Hs109|chr19        ( 728) 2187 310.8 3.1e-84
CCDS76154.1 PIK3R3 gene_id:8503|Hs109|chr1         ( 402) 1388 201.6 1.2e-51


>>CCDS3995.1 PIK3R1 gene_id:5295|Hs109|chr5               (454 aa)
 initn: 3027 init1: 3027 opt: 3027  Z-score: 2247.3  bits: 425.1 E(33420): 7.6e-119
Smith-Waterman score: 3027; 99.8% identity (100.0% similar) in 454 aa overlap (1-454:1-454)

               10        20        30        40        50        60
pF1KE2 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDPPALPPKPPKPTTVANNGMNNNMSLQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDPPALPPKPPKPTTVANNGMNNNMSLQD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 AEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 AEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 GFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 GFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 KYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIE
       .:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 EYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 KFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 KFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 IQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 IQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE2 RNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 RNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSS
              370       380       390       400       410       420

              430       440       450    
pF1KE2 LKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
       ::::::::::::::::::::::::::::::::::
CCDS39 LKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
              430       440       450    

>>CCDS3993.1 PIK3R1 gene_id:5295|Hs109|chr5               (724 aa)
 initn: 2786 init1: 2786 opt: 2788  Z-score: 2068.6  bits: 392.7 E(33420): 6.8e-109
Smith-Waterman score: 2788; 99.1% identity (99.5% similar) in 425 aa overlap (31-454:300-724)

               10        20        30         40        50         
pF1KE2 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDP-PALPPKPPKPTTVANNGMNNNMSLQ
                                     : .: :::::::::::::::::::::::::
CCDS39 PMLFRFSAASSDNTENLIKVIEILISTEWNERQPAPALPPKPPKPTTVANNGMNNNMSLQ
     270       280       290       300       310       320         

      60        70        80        90       100       110         
pF1KE2 DAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 DAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGK
     330       340       350       360       370       380         

     120       130       140       150       160       170         
pF1KE2 YGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 YGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKL
     390       400       410       420       430       440         

     180       190       200       210       220       230         
pF1KE2 HKYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYI
       :.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 HEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYI
     450       460       470       480       490       500         

     240       250       260       270       280       290         
pF1KE2 EKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 EKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPD
     510       520       530       540       550       560         

     300       310       320       330       340       350         
pF1KE2 LIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 LIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSS
     570       580       590       600       610       620         

     360       370       380       390       400       410         
pF1KE2 NRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 NRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYS
     630       640       650       660       670       680         

     420       430       440       450    
pF1KE2 SLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
       :::::::::::::::::::::::::::::::::::
CCDS39 SLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
     690       700       710       720    

>>CCDS3994.1 PIK3R1 gene_id:5295|Hs109|chr5               (424 aa)
 initn: 2771 init1: 2771 opt: 2771  Z-score: 2059.1  bits: 390.1 E(33420): 2.3e-108
Smith-Waterman score: 2771; 99.8% identity (100.0% similar) in 418 aa overlap (37-454:7-424)

         10        20        30        40        50        60      
pF1KE2 NMEDLDLEYAKTDINCGTDLMFYIEMDPPALPPKPPKPTTVANNGMNNNMSLQDAEWYWG
                                     ::::::::::::::::::::::::::::::
CCDS39                         MHNLQTLPPKPPKPTTVANNGMNNNMSLQDAEWYWG
                                       10        20        30      

         70        80        90       100       110       120      
pF1KE2 DISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 DISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPL
         40        50        60        70        80        90      

        130       140       150       160       170       180      
pF1KE2 TFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHKYNTQF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::
CCDS39 TFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQF
        100       110       120       130       140       150      

        190       200       210       220       230       240      
pF1KE2 QEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 QEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREG
        160       170       180       190       200       210      

        250       260       270       280       290       300      
pF1KE2 NEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 NEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKT
        220       230       240       250       260       270      

        310       320       330       340       350       360      
pF1KE2 RDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 RDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAEN
        280       290       300       310       320       330      

        370       380       390       400       410       420      
pF1KE2 LLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 LLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVL
        340       350       360       370       380       390      

        430       440       450    
pF1KE2 HYQHTSLVQHNDSLNVTLAYPVYAQQRR
       ::::::::::::::::::::::::::::
CCDS39 HYQHTSLVQHNDSLNVTLAYPVYAQQRR
        400       410       420    

>>CCDS56374.1 PIK3R1 gene_id:5295|Hs109|chr5              (361 aa)
 initn: 2379 init1: 2379 opt: 2379  Z-score: 1771.3  bits: 336.7 E(33420): 2.5e-92
Smith-Waterman score: 2379; 99.7% identity (100.0% similar) in 361 aa overlap (94-454:1-361)

            70        80        90       100       110       120   
pF1KE2 YWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFS
                                     ::::::::::::::::::::::::::::::
CCDS56                               MHGDYTLTLRKGGNNKLIKIFHRDGKYGFS
                                             10        20        30

           130       140       150       160       170       180   
pF1KE2 DPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHKYN
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::
CCDS56 DPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYN
               40        50        60        70        80        90

           190       200       210       220       230       240   
pF1KE2 TQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 TQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFK
              100       110       120       130       140       150

           250       260       270       280       290       300   
pF1KE2 REGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 REGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQL
              160       170       180       190       200       210

           310       320       330       340       350       360   
pF1KE2 RKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 RKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNK
              220       230       240       250       260       270

           370       380       390       400       410       420   
pF1KE2 AENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 AENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKE
              280       290       300       310       320       330

           430       440       450    
pF1KE2 LVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
       :::::::::::::::::::::::::::::::
CCDS56 LVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
              340       350       360 

>>CCDS529.1 PIK3R3 gene_id:8503|Hs109|chr1                (461 aa)
 initn: 1576 init1: 1576 opt: 2374  Z-score: 1766.2  bits: 336.1 E(33420): 4.8e-92
Smith-Waterman score: 2374; 77.8% identity (92.5% similar) in 455 aa overlap (1-451:1-455)

               10        20        30        40         50         
pF1KE2 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDPPALPPKPPKPTTVA-NNGM-NNNMSL
       ::::::.:.  : .. .. .  .:.:.::::::::::::::::: : :  ::: ....::
CCDS52 MYNTVWSMDRDDADWREVMMPYSTELIFYIEMDPPALPPKPPKPMTSAVPNGMKDSSVSL
               10        20        30        40        50        60

       60        70        80        90       100       110        
pF1KE2 QDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDG
       ::::::::::::::::.::::  :::::::::::::.::::::::::::::::::.::::
CCDS52 QDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDG
               70        80        90       100       110       120

      120       130       140       150       160       170        
pF1KE2 KYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKK
       ::::::::::.:::::::::..::::::::::::::.::::.:::::.::::::.:::::
CCDS52 KYGFSDPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQQDQLVKEDNIDAVGKK
              130       140       150       160       170       180

      180       190       200       210       220       230        
pF1KE2 LHKYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEY
       :..:..:.::::.:::::::::::::::::::::::::::::::::::::.:::..::::
CCDS52 LQEYHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSKEY
              190       200       210       220       230       240

      240       250       260       270       280       290        
pF1KE2 IEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKP
       ::.:.::::::::.::: ::::::::..:: ::. :::.:::.:: . :::::.::::::
CCDS52 IERFRREGNEKEIERIMMNYDKLKSRLGEIHDSKMRLEQDLKNQALDNREIDKKMNSIKP
              250       260       270       280       290       300

      300       310       320         330       340       350      
pF1KE2 DLIQLRKTRDQYLMWLTQKGVRQKKLNEWLG--NENTEDQYSLVEDDEDLPHHDEKTWNV
       ::::::: :::.:.::..::::::.:: :::  ::.....: . :.::.:::.::::: :
CCDS52 DLIQLRKIRDQHLVWLNHKGVRQKRLNVWLGIKNEDADENYFINEEDENLPHYDEKTWFV
              310       320       330       340       350       360

        360       370       380       390       400       410      
pF1KE2 GSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYN
        . :: .::.:: :: ::.::.:::::.::::::::.::::::::: .:: :::::::::
CCDS52 EDINRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKHCVIYSTARGYGFAEPYN
              370       380       390       400       410       420

        420       430       440       450       
pF1KE2 LYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR   
       :::::::::::::.:::::::::::: :::::.::      
CCDS52 LYSSLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQMPSLCR
              430       440       450       460 

>>CCDS76155.1 PIK3R3 gene_id:110117499|Hs109|chr1         (507 aa)
 initn: 1576 init1: 1576 opt: 2260  Z-score: 1681.7  bits: 320.6 E(33420): 2.4e-87
Smith-Waterman score: 2260; 78.2% identity (91.7% similar) in 435 aa overlap (21-451:67-501)

                         10        20        30        40          
pF1KE2           MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDPPALPPKPPKPTTVA-N
                                     :  ::  .   . : ::::::::: : :  
CCDS76 CSRRRYQQGLRGRTASSAAINPATRAMGINNTHTDTTIVWIFPPQALPPKPPKPMTSAVP
         40        50        60        70        80        90      

      50         60        70        80        90       100        
pF1KE2 NGM-NNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNN
       ::: ....::::::::::::::::::.::::  :::::::::::::.:::::::::::::
CCDS76 NGMKDSSVSLQDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNN
        100       110       120       130       140       150      

      110       120       130       140       150       160        
pF1KE2 KLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVK
       :::::.::::::::::::::.:::::::::..::::::::::::::.::::.:::::.::
CCDS76 KLIKIYHRDGKYGFSDPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQQDQLVK
        160       170       180       190       200       210      

      170       180       190       200       210       220        
pF1KE2 EDNIEAVGKKLHKYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQC
       ::::.::::::..:..:.::::.:::::::::::::::::::::::::::::::::::::
CCDS76 EDNIDAVGKKLQEYHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQC
        220       230       240       250       260       270      

      230       240       250       260       270       280        
pF1KE2 QTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYRE
       .:::..::::::.:.::::::::.::: ::::::::..:: ::. :::.:::.:: . ::
CCDS76 HTQEQHSKEYIERFRREGNEKEIERIMMNYDKLKSRLGEIHDSKMRLEQDLKNQALDNRE
        280       290       300       310       320       330      

      290       300       310       320         330       340      
pF1KE2 IDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLG--NENTEDQYSLVEDDEDL
       :::.::::::::::::: :::.:.::..::::::.:: :::  ::.....: . :.::.:
CCDS76 IDKKMNSIKPDLIQLRKIRDQHLVWLNHKGVRQKRLNVWLGIKNEDADENYFINEEDENL
        340       350       360       370       380       390      

        350       360       370       380       390       400      
pF1KE2 PHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTA
       ::.::::: : . :: .::.:: :: ::.::.:::::.::::::::.::::::::: .::
CCDS76 PHYDEKTWFVEDINRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKHCVIYSTA
        400       410       420       430       440       450      

        410       420       430       440       450       
pF1KE2 TGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR   
        ::::::::::::::::::::::.:::::::::::: :::::.::      
CCDS76 RGYGFAEPYNLYSSLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQMPSLCR
        460       470       480       490       500       

>>CCDS12371.1 PIK3R2 gene_id:5296|Hs109|chr19             (728 aa)
 initn: 2143 init1: 1514 opt: 2187  Z-score: 1625.9  bits: 310.8 E(33420): 3.1e-84
Smith-Waterman score: 2187; 76.2% identity (92.7% similar) in 424 aa overlap (31-450:296-718)

               10        20        30        40           50       
pF1KE2 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDPPALPPKPPK--P-TTVANNGMNNNMS
                                     :. ::::::::::  : .::  :: ..  :
CCDS12 PGGAPDGSEPSPDFPALLVEKLLQEHLEEQEVAPPALPPKPPKAKPASTVLANG-GSPPS
         270       280       290       300       310        320    

        60        70        80        90       100       110       
pF1KE2 LQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRD
       ::::::::::::::::::::::: ::::::::::.:..:.:::::::::::::::.::::
CCDS12 LQDAEWYWGDISREEVNEKLRDTPDGTFLVRDASSKIQGEYTLTLRKGGNNKLIKVFHRD
          330       340       350       360       370       380    

       120       130       140       150       160       170       
pF1KE2 GKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGK
       :.::::.:::: :::.::::::.::::::: :::..::::::::::::.::::..:::: 
CCDS12 GHYGFSEPLTFCSVVDLINHYRHESLAQYNAKLDTRLLYPVSKYQQDQIVKEDSVEAVGA
          390       400       410       420       430       440    

       180       190       200       210       220       230       
pF1KE2 KLHKYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKE
       .:. :. :.:.::::::.:::::::::::.:::::::::::::::::::: ::::. :::
CCDS12 QLKVYHQQYQDKSREYDQLYEEYTRTSQELQMKRTAIEAFNETIKIFEEQGQTQEKCSKE
          450       460       470       480       490       500    

       240       250       260       270       280       290       
pF1KE2 YIEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIK
       :.:.:.:::::::.:::. : ..:::::.:: .:: .::..:. ::.. :::::::::.:
CCDS12 YLERFRREGNEKEMQRILLNSERLKSRIAEIHESRTKLEQQLRAQASDNREIDKRMNSLK
          510       520       530       540       550       560    

       300       310       320       330        340       350      
pF1KE2 PDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNEN-TEDQYSLVEDDEDLPHHDEKTWNV
       :::.:::: :::::.::::::.::::.::::: .: :::::.:.::..:::::.:.:: :
CCDS12 PDLMQLRKIRDQYLVWLTQKGARQKKINEWLGIKNETEDQYALMEDEDDLPHHEERTWYV
          570       580       590       600       610       620    

        360       370       380       390       400       410      
pF1KE2 GSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYN
       :. ::..::..: ::::::::.::::..:::::::::::..::::: .::::.:::::::
CCDS12 GKINRTQAEEMLSGKRDGTFLIRESSQRGCYACSVVVDGDTKHCVIYRTATGFGFAEPYN
          630       640       650       660       670       680    

        420       430       440       450          
pF1KE2 LYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR      
       ::.:::::::::::.:::::::.:.::::.:: :          
CCDS12 LYGSLKELVLHYQHASLVQHNDALTVTLAHPVRAPGPGPPPAAR
          690       700       710       720        

>>CCDS76154.1 PIK3R3 gene_id:8503|Hs109|chr1              (402 aa)
 initn: 1982 init1: 1176 opt: 1388  Z-score: 1040.7  bits: 201.6 E(33420): 1.2e-51
Smith-Waterman score: 1964; 68.1% identity (80.9% similar) in 455 aa overlap (1-451:1-396)

               10        20        30        40         50         
pF1KE2 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDPPALPPKPPKPTTVA-NNGM-NNNMSL
       ::::::.:.  : .. .. .  .:.:.::::::::::::::::: : :  ::: ....::
CCDS76 MYNTVWSMDRDDADWREVMMPYSTELIFYIEMDPPALPPKPPKPMTSAVPNGMKDSSVSL
               10        20        30        40        50        60

       60        70        80        90       100       110        
pF1KE2 QDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDG
       ::::::::::::::::.::::  :::::::::::::.::::::::::::::::::.::::
CCDS76 QDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDG
               70        80        90       100       110       120

      120       130       140       150       160       170        
pF1KE2 KYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKK
       ::::::::::.:::::::::..::::::::::::::.::::.:::::.::::::.:::::
CCDS76 KYGFSDPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQQDQLVKEDNIDAVGKK
              130       140       150       160       170       180

      180       190       200       210       220       230        
pF1KE2 LHKYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEY
       :..:..:.::::.:::::::::::::::::::::::::::::::::::::.:::..::::
CCDS76 LQEYHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSKEY
              190       200       210       220       230       240

      240       250       260       270       280       290        
pF1KE2 IEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKP
       ::.:.::::::::.:                                             
CCDS76 IERFRREGNEKEIER---------------------------------------------
              250                                                  

      300       310       320         330       340       350      
pF1KE2 DLIQLRKTRDQYLMWLTQKGVRQKKLNEWLG--NENTEDQYSLVEDDEDLPHHDEKTWNV
                     ::..::::::.:: :::  ::.....: . :.::.:::.::::: :
CCDS76 --------------WLNHKGVRQKRLNVWLGIKNEDADENYFINEEDENLPHYDEKTWFV
                       260       270       280       290       300 

        360       370       380       390       400       410      
pF1KE2 GSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYN
        . :: .::.:: :: ::.::.:::::.::::::::.::::::::: .:: :::::::::
CCDS76 EDINRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKHCVIYSTARGYGFAEPYN
             310       320       330       340       350       360 

        420       430       440       450       
pF1KE2 LYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR   
       :::::::::::::.:::::::::::: :::::.::      
CCDS76 LYSSLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQMPSLCR
             370       380       390       400  




454 residues in 1 query   sequences
18921897 residues in 33420 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Oct 24 21:39:44 2019 done: Thu Oct 24 21:39:44 2019
 Total Scan time:  1.420 Total Display time:  0.050

Function used was FASTA [36.3.4 Apr, 2011]
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