Result of FASTA (omim) for
pF1KE0969
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0969, 527 aa
1>>>pF1KE0969 527 - 527 aa - 527 aa
Library: /omim/omim.rfq.tfa
64369986 residues in 92320 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.1223+/-0.0006; mu= 3.0330+/- 0.037
mean_var=695.4715+/-156.924, 0's: 0 Z-trim(118.1): 1370 B-trim: 1886 in 1/53
Lambda= 0.048633
statistics sampled from 29811 (31921) to 29811 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.346), width: 16
Scan time: 4.820
The best scores are: opt bits E(92320)
NP_003319 (OMIM: 600058) tyrosine-protein kinase T ( 527) 3597 268.6 3.6e-71
XP_024309968 (OMIM: 600058) tyrosine-protein kinas ( 530) 3424 256.5 1.6e-67
XP_016864070 (OMIM: 600058) tyrosine-protein kinas ( 502) 3405 255.1 4e-67
XP_011512049 (OMIM: 600058) tyrosine-protein kinas ( 508) 2588 197.8 7.2e-50
XP_016864071 (OMIM: 600058) tyrosine-protein kinas ( 338) 2306 177.7 5.4e-44
XP_016864058 (OMIM: 600583) tyrosine-protein kinas ( 515) 2051 160.1 1.6e-38
XP_011512039 (OMIM: 600583) tyrosine-protein kinas ( 595) 2051 160.2 1.7e-38
XP_024309961 (OMIM: 600583) tyrosine-protein kinas ( 631) 2051 160.3 1.7e-38
NP_003206 (OMIM: 600583) tyrosine-protein kinase T ( 631) 2051 160.3 1.7e-38
XP_011512050 (OMIM: 600058) tyrosine-protein kinas ( 289) 1966 153.7 7.7e-37
NP_000052 (OMIM: 300300,300755,307200) tyrosine-pr ( 659) 1935 152.2 5e-36
NP_001274273 (OMIM: 300300,300755,307200) tyrosine ( 693) 1935 152.2 5.1e-36
XP_016864932 (OMIM: 186973,613011) tyrosine-protei ( 495) 1897 149.3 2.8e-35
NP_005537 (OMIM: 186973,613011) tyrosine-protein k ( 620) 1897 149.5 3.1e-35
NP_975010 (OMIM: 300101) cytoplasmic tyrosine-prot ( 675) 1568 126.4 2.8e-28
NP_001712 (OMIM: 300101) cytoplasmic tyrosine-prot ( 675) 1568 126.4 2.8e-28
NP_001307795 (OMIM: 300101) cytoplasmic tyrosine-p ( 674) 1560 125.9 4.2e-28
XP_011512043 (OMIM: 600583) tyrosine-protein kinas ( 466) 1222 101.9 4.9e-21
NP_694592 (OMIM: 137025) tyrosine-protein kinase F ( 534) 1135 95.9 3.6e-19
XP_016866140 (OMIM: 137025) tyrosine-protein kinas ( 537) 1135 95.9 3.6e-19
XP_016866141 (OMIM: 137025) tyrosine-protein kinas ( 537) 1135 95.9 3.6e-19
NP_002028 (OMIM: 137025) tyrosine-protein kinase F ( 537) 1135 95.9 3.6e-19
XP_016866139 (OMIM: 137025) tyrosine-protein kinas ( 537) 1135 95.9 3.6e-19
XP_016866142 (OMIM: 137025) tyrosine-protein kinas ( 537) 1135 95.9 3.6e-19
NP_001357458 (OMIM: 137025) tyrosine-protein kinas ( 537) 1135 95.9 3.6e-19
NP_002341 (OMIM: 165120) tyrosine-protein kinase L ( 512) 1133 95.7 3.9e-19
NP_001165602 (OMIM: 142370) tyrosine-protein kinas ( 504) 1132 95.6 4e-19
NP_001165601 (OMIM: 142370) tyrosine-protein kinas ( 525) 1132 95.6 4.1e-19
NP_001165600 (OMIM: 142370) tyrosine-protein kinas ( 505) 1131 95.5 4.3e-19
NP_001165604 (OMIM: 142370) tyrosine-protein kinas ( 505) 1131 95.5 4.3e-19
NP_001165603 (OMIM: 142370) tyrosine-protein kinas ( 506) 1131 95.5 4.3e-19
NP_002101 (OMIM: 142370) tyrosine-protein kinase H ( 526) 1131 95.6 4.3e-19
XP_016868905 (OMIM: 165120) tyrosine-protein kinas ( 491) 1129 95.4 4.6e-19
NP_001104567 (OMIM: 165120) tyrosine-protein kinas ( 491) 1129 95.4 4.6e-19
XP_011515831 (OMIM: 165120) tyrosine-protein kinas ( 682) 1131 95.8 4.9e-19
NP_005347 (OMIM: 153390,615758) tyrosine-protein k ( 509) 1128 95.3 4.9e-19
NP_001036236 (OMIM: 153390,615758) tyrosine-protei ( 509) 1128 95.3 4.9e-19
NP_005148 (OMIM: 189980,608232,617602) tyrosine-pr (1130) 1135 96.5 5e-19
NP_009297 (OMIM: 189980,608232,617602) tyrosine-pr (1149) 1135 96.5 5e-19
NP_001706 (OMIM: 191305,613375) tyrosine-protein k ( 505) 1121 94.8 6.9e-19
XP_024302815 (OMIM: 153390,615758) tyrosine-protei ( 567) 1119 94.8 8e-19
XP_024302814 (OMIM: 153390,615758) tyrosine-protei ( 567) 1119 94.8 8e-19
NP_938033 (OMIM: 114500,190090,616937) proto-oncog ( 536) 1108 94.0 1.3e-18
NP_005408 (OMIM: 114500,190090,616937) proto-oncog ( 536) 1108 94.0 1.3e-18
XP_011527315 (OMIM: 114500,190090,616937) proto-on ( 536) 1108 94.0 1.3e-18
NP_001129473 (OMIM: 164690) tyrosine-protein kinas ( 542) 1103 93.6 1.7e-18
NP_001036194 (OMIM: 164940) tyrosine-protein kinas ( 529) 1102 93.5 1.8e-18
XP_011539312 (OMIM: 164940) tyrosine-protein kinas ( 529) 1102 93.5 1.8e-18
NP_005239 (OMIM: 164940) tyrosine-protein kinase F ( 529) 1102 93.5 1.8e-18
XP_006710515 (OMIM: 164940) tyrosine-protein kinas ( 529) 1102 93.5 1.8e-18
>>NP_003319 (OMIM: 600058) tyrosine-protein kinase TXK [ (527 aa)
initn: 3597 init1: 3597 opt: 3597 Z-score: 1399.4 bits: 268.6 E(92320): 3.6e-71
Smith-Waterman score: 3597; 99.8% identity (100.0% similar) in 527 aa overlap (1-527:1-527)
10 20 30 40 50 60
pF1KE0 MILSSYNTIQSVFCCCCCCSVQKRQMRTQISLSTDEELPEKYTQHRRPWLSQLSNKKQSN
::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
NP_003 MILSSYNTIQSVFCCCCCCSVQKRQMRTQISLSTDEELPEKYTQRRRPWLSQLSNKKQSN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 TGRVQPSKRKPLPPLPPSEVAEEKIQVKALYDFLPREPCNLALRRAEEYLILEKYNPHWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TGRVQPSKRKPLPPLPPSEVAEEKIQVKALYDFLPREPCNLALRRAEEYLILEKYNPHWW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 KARDRLGNEGLIPSNYVTENKITNLEIYEWYHRNITRNQAEHLLRQESKEGAFIVRDSRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KARDRLGNEGLIPSNYVTENKITNLEIYEWYHRNITRNQAEHLLRQESKEGAFIVRDSRH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 LGSYTISVFMGARRSTEAAIKHYQIKKNDSGQWYVAERHAFQSIPELIWYHQHNAAGLMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LGSYTISVFMGARRSTEAAIKHYQIKKNDSGQWYVAERHAFQSIPELIWYHQHNAAGLMT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 RLRYPVGLMGSCLPATAGFSYEKWEIDPSELAFIKEIGSGQFGVVHLGEWRSHIQVAIKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RLRYPVGLMGSCLPATAGFSYEKWEIDPSELAFIKEIGSGQFGVVHLGEWRSHIQVAIKA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 INEGSMSEEDFIEEAKVMMKLSHSKLVQLYGVCIQRKPLYIVTEFMENGCLLNYLRENKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 INEGSMSEEDFIEEAKVMMKLSHSKLVQLYGVCIQRKPLYIVTEFMENGCLLNYLRENKG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 KLRKEMLLSVCQDICEGMEYLERNGYIHRDLAARNCLVSSTCIVKISDFGMTRYVLDDEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KLRKEMLLSVCQDICEGMEYLERNGYIHRDLAARNCLVSSTCIVKISDFGMTRYVLDDEY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 VSSFGAKFPIKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VSSFGAKFPIKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAIS
430 440 450 460 470 480
490 500 510 520
pF1KE0 EGFRLYRPHLAPMSIYEVMYSCWHEKPEGRPTFAELLRAVTEIAETW
:::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EGFRLYRPHLAPMSIYEVMYSCWHEKPEGRPTFAELLRAVTEIAETW
490 500 510 520
>>XP_024309968 (OMIM: 600058) tyrosine-protein kinase TX (530 aa)
initn: 3424 init1: 3424 opt: 3424 Z-score: 1333.8 bits: 256.5 E(92320): 1.6e-67
Smith-Waterman score: 3424; 99.6% identity (99.8% similar) in 506 aa overlap (22-527:25-530)
10 20 30 40 50
pF1KE0 MILSSYNTIQSVFCCCCCCSVQKRQMRTQISLSTDEELPEKYTQHRRPWLSQLSNKK
: :::::::::::::::::::::.::::::::::::
XP_024 MVELGFKLLFLITIPCLFITKRHHQMRQMRTQISLSTDEELPEKYTQRRRPWLSQLSNKK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 QSNTGRVQPSKRKPLPPLPPSEVAEEKIQVKALYDFLPREPCNLALRRAEEYLILEKYNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 QSNTGRVQPSKRKPLPPLPPSEVAEEKIQVKALYDFLPREPCNLALRRAEEYLILEKYNP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 HWWKARDRLGNEGLIPSNYVTENKITNLEIYEWYHRNITRNQAEHLLRQESKEGAFIVRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 HWWKARDRLGNEGLIPSNYVTENKITNLEIYEWYHRNITRNQAEHLLRQESKEGAFIVRD
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 SRHLGSYTISVFMGARRSTEAAIKHYQIKKNDSGQWYVAERHAFQSIPELIWYHQHNAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 SRHLGSYTISVFMGARRSTEAAIKHYQIKKNDSGQWYVAERHAFQSIPELIWYHQHNAAG
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE0 LMTRLRYPVGLMGSCLPATAGFSYEKWEIDPSELAFIKEIGSGQFGVVHLGEWRSHIQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 LMTRLRYPVGLMGSCLPATAGFSYEKWEIDPSELAFIKEIGSGQFGVVHLGEWRSHIQVA
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE0 IKAINEGSMSEEDFIEEAKVMMKLSHSKLVQLYGVCIQRKPLYIVTEFMENGCLLNYLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 IKAINEGSMSEEDFIEEAKVMMKLSHSKLVQLYGVCIQRKPLYIVTEFMENGCLLNYLRE
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE0 NKGKLRKEMLLSVCQDICEGMEYLERNGYIHRDLAARNCLVSSTCIVKISDFGMTRYVLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 NKGKLRKEMLLSVCQDICEGMEYLERNGYIHRDLAARNCLVSSTCIVKISDFGMTRYVLD
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE0 DEYVSSFGAKFPIKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 DEYVSSFGAKFPIKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVE
430 440 450 460 470 480
480 490 500 510 520
pF1KE0 AISEGFRLYRPHLAPMSIYEVMYSCWHEKPEGRPTFAELLRAVTEIAETW
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 AISEGFRLYRPHLAPMSIYEVMYSCWHEKPEGRPTFAELLRAVTEIAETW
490 500 510 520 530
>>XP_016864070 (OMIM: 600058) tyrosine-protein kinase TX (502 aa)
initn: 3405 init1: 3405 opt: 3405 Z-score: 1326.8 bits: 255.1 E(92320): 4e-67
Smith-Waterman score: 3405; 99.8% identity (100.0% similar) in 502 aa overlap (26-527:1-502)
10 20 30 40 50 60
pF1KE0 MILSSYNTIQSVFCCCCCCSVQKRQMRTQISLSTDEELPEKYTQHRRPWLSQLSNKKQSN
:::::::::::::::::::.:::::::::::::::
XP_016 MRTQISLSTDEELPEKYTQRRRPWLSQLSNKKQSN
10 20 30
70 80 90 100 110 120
pF1KE0 TGRVQPSKRKPLPPLPPSEVAEEKIQVKALYDFLPREPCNLALRRAEEYLILEKYNPHWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGRVQPSKRKPLPPLPPSEVAEEKIQVKALYDFLPREPCNLALRRAEEYLILEKYNPHWW
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE0 KARDRLGNEGLIPSNYVTENKITNLEIYEWYHRNITRNQAEHLLRQESKEGAFIVRDSRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KARDRLGNEGLIPSNYVTENKITNLEIYEWYHRNITRNQAEHLLRQESKEGAFIVRDSRH
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE0 LGSYTISVFMGARRSTEAAIKHYQIKKNDSGQWYVAERHAFQSIPELIWYHQHNAAGLMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGSYTISVFMGARRSTEAAIKHYQIKKNDSGQWYVAERHAFQSIPELIWYHQHNAAGLMT
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE0 RLRYPVGLMGSCLPATAGFSYEKWEIDPSELAFIKEIGSGQFGVVHLGEWRSHIQVAIKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLRYPVGLMGSCLPATAGFSYEKWEIDPSELAFIKEIGSGQFGVVHLGEWRSHIQVAIKA
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE0 INEGSMSEEDFIEEAKVMMKLSHSKLVQLYGVCIQRKPLYIVTEFMENGCLLNYLRENKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INEGSMSEEDFIEEAKVMMKLSHSKLVQLYGVCIQRKPLYIVTEFMENGCLLNYLRENKG
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE0 KLRKEMLLSVCQDICEGMEYLERNGYIHRDLAARNCLVSSTCIVKISDFGMTRYVLDDEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLRKEMLLSVCQDICEGMEYLERNGYIHRDLAARNCLVSSTCIVKISDFGMTRYVLDDEY
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE0 VSSFGAKFPIKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSSFGAKFPIKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAIS
400 410 420 430 440 450
490 500 510 520
pF1KE0 EGFRLYRPHLAPMSIYEVMYSCWHEKPEGRPTFAELLRAVTEIAETW
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGFRLYRPHLAPMSIYEVMYSCWHEKPEGRPTFAELLRAVTEIAETW
460 470 480 490 500
>>XP_011512049 (OMIM: 600058) tyrosine-protein kinase TX (508 aa)
initn: 3273 init1: 2574 opt: 2588 Z-score: 1016.9 bits: 197.8 E(92320): 7.2e-50
Smith-Waterman score: 3233; 95.3% identity (95.5% similar) in 506 aa overlap (22-527:25-508)
10 20 30 40 50
pF1KE0 MILSSYNTIQSVFCCCCCCSVQKRQMRTQISLSTDEELPEKYTQHRRPWLSQLSNKK
: :::::::::::::::::::::.::::::::::::
XP_011 MVELGFKLLFLITIPCLFITKRHHQMRQMRTQISLSTDEELPEKYTQRRRPWLSQLSNKK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 QSNTGRVQPSKRKPLPPLPPSEVAEEKIQVKALYDFLPREPCNLALRRAEEYLILEKYNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSNTGRVQPSKRKPLPPLPPSEVAEEKIQVKALYDFLPREPCNLALRRAEEYLILEKYNP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 HWWKARDRLGNEGLIPSNYVTENKITNLEIYEWYHRNITRNQAEHLLRQESKEGAFIVRD
:::::::::: ::::::::::::::::::::::::::::
XP_011 HWWKARDRLG----------------------WYHRNITRNQAEHLLRQESKEGAFIVRD
130 140 150
180 190 200 210 220 230
pF1KE0 SRHLGSYTISVFMGARRSTEAAIKHYQIKKNDSGQWYVAERHAFQSIPELIWYHQHNAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRHLGSYTISVFMGARRSTEAAIKHYQIKKNDSGQWYVAERHAFQSIPELIWYHQHNAAG
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE0 LMTRLRYPVGLMGSCLPATAGFSYEKWEIDPSELAFIKEIGSGQFGVVHLGEWRSHIQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMTRLRYPVGLMGSCLPATAGFSYEKWEIDPSELAFIKEIGSGQFGVVHLGEWRSHIQVA
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE0 IKAINEGSMSEEDFIEEAKVMMKLSHSKLVQLYGVCIQRKPLYIVTEFMENGCLLNYLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKAINEGSMSEEDFIEEAKVMMKLSHSKLVQLYGVCIQRKPLYIVTEFMENGCLLNYLRE
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE0 NKGKLRKEMLLSVCQDICEGMEYLERNGYIHRDLAARNCLVSSTCIVKISDFGMTRYVLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKGKLRKEMLLSVCQDICEGMEYLERNGYIHRDLAARNCLVSSTCIVKISDFGMTRYVLD
340 350 360 370 380 390
420 430 440 450 460 470
pF1KE0 DEYVSSFGAKFPIKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEYVSSFGAKFPIKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVE
400 410 420 430 440 450
480 490 500 510 520
pF1KE0 AISEGFRLYRPHLAPMSIYEVMYSCWHEKPEGRPTFAELLRAVTEIAETW
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AISEGFRLYRPHLAPMSIYEVMYSCWHEKPEGRPTFAELLRAVTEIAETW
460 470 480 490 500
>>XP_016864071 (OMIM: 600058) tyrosine-protein kinase TX (338 aa)
initn: 2306 init1: 2306 opt: 2306 Z-score: 911.4 bits: 177.7 E(92320): 5.4e-44
Smith-Waterman score: 2306; 100.0% identity (100.0% similar) in 338 aa overlap (190-527:1-338)
160 170 180 190 200 210
pF1KE0 AEHLLRQESKEGAFIVRDSRHLGSYTISVFMGARRSTEAAIKHYQIKKNDSGQWYVAERH
::::::::::::::::::::::::::::::
XP_016 MGARRSTEAAIKHYQIKKNDSGQWYVAERH
10 20 30
220 230 240 250 260 270
pF1KE0 AFQSIPELIWYHQHNAAGLMTRLRYPVGLMGSCLPATAGFSYEKWEIDPSELAFIKEIGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFQSIPELIWYHQHNAAGLMTRLRYPVGLMGSCLPATAGFSYEKWEIDPSELAFIKEIGS
40 50 60 70 80 90
280 290 300 310 320 330
pF1KE0 GQFGVVHLGEWRSHIQVAIKAINEGSMSEEDFIEEAKVMMKLSHSKLVQLYGVCIQRKPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GQFGVVHLGEWRSHIQVAIKAINEGSMSEEDFIEEAKVMMKLSHSKLVQLYGVCIQRKPL
100 110 120 130 140 150
340 350 360 370 380 390
pF1KE0 YIVTEFMENGCLLNYLRENKGKLRKEMLLSVCQDICEGMEYLERNGYIHRDLAARNCLVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YIVTEFMENGCLLNYLRENKGKLRKEMLLSVCQDICEGMEYLERNGYIHRDLAARNCLVS
160 170 180 190 200 210
400 410 420 430 440 450
pF1KE0 STCIVKISDFGMTRYVLDDEYVSSFGAKFPIKWSPPEVFLFNKYSSKSDVWSFGVLMWEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STCIVKISDFGMTRYVLDDEYVSSFGAKFPIKWSPPEVFLFNKYSSKSDVWSFGVLMWEV
220 230 240 250 260 270
460 470 480 490 500 510
pF1KE0 FTEGKMPFENKSNLQVVEAISEGFRLYRPHLAPMSIYEVMYSCWHEKPEGRPTFAELLRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTEGKMPFENKSNLQVVEAISEGFRLYRPHLAPMSIYEVMYSCWHEKPEGRPTFAELLRA
280 290 300 310 320 330
520
pF1KE0 VTEIAETW
::::::::
XP_016 VTEIAETW
>>XP_016864058 (OMIM: 600583) tyrosine-protein kinase Te (515 aa)
initn: 2038 init1: 1574 opt: 2051 Z-score: 813.3 bits: 160.1 E(92320): 1.6e-38
Smith-Waterman score: 2051; 62.6% identity (85.1% similar) in 463 aa overlap (65-525:46-508)
40 50 60 70 80 90
pF1KE0 DEELPEKYTQHRRPWLSQLSNKKQSNTGRVQPSKRKPLPPLPPSEVAEEKIQVKALYDFL
. .::.: ::.: : . . : :.:::
XP_016 CCRQTEKLAPGCEKYNLFESSIRKALPPAPETKKRRPPPPIPLEEEDNSEEIVVAMYDFQ
20 30 40 50 60 70
100 110 120 130 140 150
pF1KE0 PREPCNLALRRAEEYLILEKYNPHWWKARDRLGNEGLIPSNYVTENKITNLEIYEWYHRN
: .: :.:..::::::: . :::.:::. :::: ::::::: .: .::. :::: ::
XP_016 AAEGHDLRLERGQEYLILEKNDVHWWRARDKYGNEGYIPSNYVTGKKSNNLDQYEWYCRN
80 90 100 110 120 130
160 170 180 190 200 210
pF1KE0 ITRNQAEHLLRQESKEGAFIVRDSRHLGSYTISVFMGARRSTEAAIKHYQIKKNDSG--Q
..:..::.:::.:.:::.:.:::: . : ::.:.. ....::.::.. .. .
XP_016 MNRSKAEQLLRSEDKEGGFMVRDSSQPGLYTVSLYTKFGGEGSSGFRHYHIKETTTSPKK
140 150 160 170 180 190
220 230 240 250 260 270
pF1KE0 WYVAERHAFQSIPELIWYHQHNAAGLMTRLRYPVGLMGSCLPATAGFSYEKWEIDPSELA
.:.::.::: ::::.: ::.::::::.:::::::.. :. :.:::::::::::.::::.
XP_016 YYLAEKHAFGSIPEIIEYHKHNAAGLVTRLRYPVSVKGKNAPTTAGFSYEKWEINPSELT
200 210 220 230 240 250
280 290 300 310 320 330
pF1KE0 FIKEIGSGQFGVVHLGEWRSHIQVAIKAINEGSMSEEDFIEEAKVMMKLSHSKLVQLYGV
:..:.::: ::::.::.::.. .:::::: ::.: ::::::::::::::.: ::::::::
XP_016 FMRELGSGLFGVVRLGKWRAQYKVAIKAIREGAMCEEDFIEEAKVMMKLTHPKLVQLYGV
260 270 280 290 300 310
340 350 360 370 380 390
pF1KE0 CIQRKPLYIVTEFMENGCLLNYLRENKGKLRKEMLLSVCQDICEGMEYLERNGYIHRDLA
: :.::.:::::::: :::::.::. .:.. ...:::.:::.::::::::::..::::::
XP_016 CTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDVLLSMCQDVCEGMEYLERNSFIHRDLA
320 330 340 350 360 370
400 410 420 430 440 450
pF1KE0 ARNCLVSSTCIVKISDFGMTRYVLDDEYVSSFGAKFPIKWSPPEVFLFNKYSSKSDVWSF
::::::: . .::.:::::.::::::.:.:: :::::.:: ::::: ....:::::::::
XP_016 ARNCLVSEAGVVKVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSF
380 390 400 410 420 430
460 470 480 490 500 510
pF1KE0 GVLMWEVFTEGKMPFENKSNLQVVEAISEGFRLYRPHLAPMSIYEVMYSCWHEKPEGRPT
:::::::::::.::::. .: .:: ...: :::.:.:: .:::: ::.:::::::.
XP_016 GVLMWEVFTEGRMPFEKYTNYEVVTMVTRGHRLYQPKLASNYVYEVMLRCWQEKPEGRPS
440 450 460 470 480 490
520
pF1KE0 FAELLRAVTEIAETW
: .:::.. :..:
XP_016 FEDLLRTIDELVECEETFGR
500 510
>>XP_011512039 (OMIM: 600583) tyrosine-protein kinase Te (595 aa)
initn: 2038 init1: 1574 opt: 2051 Z-score: 812.8 bits: 160.2 E(92320): 1.7e-38
Smith-Waterman score: 2051; 62.6% identity (85.1% similar) in 463 aa overlap (65-525:126-588)
40 50 60 70 80 90
pF1KE0 DEELPEKYTQHRRPWLSQLSNKKQSNTGRVQPSKRKPLPPLPPSEVAEEKIQVKALYDFL
. .::.: ::.: : . . : :.:::
XP_011 CCRQTEKLAPGCEKYNLFESSIRKALPPAPETKKRRPPPPIPLEEEDNSEEIVVAMYDFQ
100 110 120 130 140 150
100 110 120 130 140 150
pF1KE0 PREPCNLALRRAEEYLILEKYNPHWWKARDRLGNEGLIPSNYVTENKITNLEIYEWYHRN
: .: :.:..::::::: . :::.:::. :::: ::::::: .: .::. :::: ::
XP_011 AAEGHDLRLERGQEYLILEKNDVHWWRARDKYGNEGYIPSNYVTGKKSNNLDQYEWYCRN
160 170 180 190 200 210
160 170 180 190 200 210
pF1KE0 ITRNQAEHLLRQESKEGAFIVRDSRHLGSYTISVFMGARRSTEAAIKHYQIKKNDSG--Q
..:..::.:::.:.:::.:.:::: . : ::.:.. ....::.::.. .. .
XP_011 MNRSKAEQLLRSEDKEGGFMVRDSSQPGLYTVSLYTKFGGEGSSGFRHYHIKETTTSPKK
220 230 240 250 260 270
220 230 240 250 260 270
pF1KE0 WYVAERHAFQSIPELIWYHQHNAAGLMTRLRYPVGLMGSCLPATAGFSYEKWEIDPSELA
.:.::.::: ::::.: ::.::::::.:::::::.. :. :.:::::::::::.::::.
XP_011 YYLAEKHAFGSIPEIIEYHKHNAAGLVTRLRYPVSVKGKNAPTTAGFSYEKWEINPSELT
280 290 300 310 320 330
280 290 300 310 320 330
pF1KE0 FIKEIGSGQFGVVHLGEWRSHIQVAIKAINEGSMSEEDFIEEAKVMMKLSHSKLVQLYGV
:..:.::: ::::.::.::.. .:::::: ::.: ::::::::::::::.: ::::::::
XP_011 FMRELGSGLFGVVRLGKWRAQYKVAIKAIREGAMCEEDFIEEAKVMMKLTHPKLVQLYGV
340 350 360 370 380 390
340 350 360 370 380 390
pF1KE0 CIQRKPLYIVTEFMENGCLLNYLRENKGKLRKEMLLSVCQDICEGMEYLERNGYIHRDLA
: :.::.:::::::: :::::.::. .:.. ...:::.:::.::::::::::..::::::
XP_011 CTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDVLLSMCQDVCEGMEYLERNSFIHRDLA
400 410 420 430 440 450
400 410 420 430 440 450
pF1KE0 ARNCLVSSTCIVKISDFGMTRYVLDDEYVSSFGAKFPIKWSPPEVFLFNKYSSKSDVWSF
::::::: . .::.:::::.::::::.:.:: :::::.:: ::::: ....:::::::::
XP_011 ARNCLVSEAGVVKVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSF
460 470 480 490 500 510
460 470 480 490 500 510
pF1KE0 GVLMWEVFTEGKMPFENKSNLQVVEAISEGFRLYRPHLAPMSIYEVMYSCWHEKPEGRPT
:::::::::::.::::. .: .:: ...: :::.:.:: .:::: ::.:::::::.
XP_011 GVLMWEVFTEGRMPFEKYTNYEVVTMVTRGHRLYQPKLASNYVYEVMLRCWQEKPEGRPS
520 530 540 550 560 570
520
pF1KE0 FAELLRAVTEIAETW
: .:::.. :..:
XP_011 FEDLLRTIDELVECEETFGR
580 590
>>XP_024309961 (OMIM: 600583) tyrosine-protein kinase Te (631 aa)
initn: 2038 init1: 1574 opt: 2051 Z-score: 812.6 bits: 160.3 E(92320): 1.7e-38
Smith-Waterman score: 2051; 62.6% identity (85.1% similar) in 463 aa overlap (65-525:162-624)
40 50 60 70 80 90
pF1KE0 DEELPEKYTQHRRPWLSQLSNKKQSNTGRVQPSKRKPLPPLPPSEVAEEKIQVKALYDFL
. .::.: ::.: : . . : :.:::
XP_024 CCRQTEKLAPGCEKYNLFESSIRKALPPAPETKKRRPPPPIPLEEEDNSEEIVVAMYDFQ
140 150 160 170 180 190
100 110 120 130 140 150
pF1KE0 PREPCNLALRRAEEYLILEKYNPHWWKARDRLGNEGLIPSNYVTENKITNLEIYEWYHRN
: .: :.:..::::::: . :::.:::. :::: ::::::: .: .::. :::: ::
XP_024 AAEGHDLRLERGQEYLILEKNDVHWWRARDKYGNEGYIPSNYVTGKKSNNLDQYEWYCRN
200 210 220 230 240 250
160 170 180 190 200 210
pF1KE0 ITRNQAEHLLRQESKEGAFIVRDSRHLGSYTISVFMGARRSTEAAIKHYQIKKNDSG--Q
..:..::.:::.:.:::.:.:::: . : ::.:.. ....::.::.. .. .
XP_024 MNRSKAEQLLRSEDKEGGFMVRDSSQPGLYTVSLYTKFGGEGSSGFRHYHIKETTTSPKK
260 270 280 290 300 310
220 230 240 250 260 270
pF1KE0 WYVAERHAFQSIPELIWYHQHNAAGLMTRLRYPVGLMGSCLPATAGFSYEKWEIDPSELA
.:.::.::: ::::.: ::.::::::.:::::::.. :. :.:::::::::::.::::.
XP_024 YYLAEKHAFGSIPEIIEYHKHNAAGLVTRLRYPVSVKGKNAPTTAGFSYEKWEINPSELT
320 330 340 350 360 370
280 290 300 310 320 330
pF1KE0 FIKEIGSGQFGVVHLGEWRSHIQVAIKAINEGSMSEEDFIEEAKVMMKLSHSKLVQLYGV
:..:.::: ::::.::.::.. .:::::: ::.: ::::::::::::::.: ::::::::
XP_024 FMRELGSGLFGVVRLGKWRAQYKVAIKAIREGAMCEEDFIEEAKVMMKLTHPKLVQLYGV
380 390 400 410 420 430
340 350 360 370 380 390
pF1KE0 CIQRKPLYIVTEFMENGCLLNYLRENKGKLRKEMLLSVCQDICEGMEYLERNGYIHRDLA
: :.::.:::::::: :::::.::. .:.. ...:::.:::.::::::::::..::::::
XP_024 CTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDVLLSMCQDVCEGMEYLERNSFIHRDLA
440 450 460 470 480 490
400 410 420 430 440 450
pF1KE0 ARNCLVSSTCIVKISDFGMTRYVLDDEYVSSFGAKFPIKWSPPEVFLFNKYSSKSDVWSF
::::::: . .::.:::::.::::::.:.:: :::::.:: ::::: ....:::::::::
XP_024 ARNCLVSEAGVVKVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSF
500 510 520 530 540 550
460 470 480 490 500 510
pF1KE0 GVLMWEVFTEGKMPFENKSNLQVVEAISEGFRLYRPHLAPMSIYEVMYSCWHEKPEGRPT
:::::::::::.::::. .: .:: ...: :::.:.:: .:::: ::.:::::::.
XP_024 GVLMWEVFTEGRMPFEKYTNYEVVTMVTRGHRLYQPKLASNYVYEVMLRCWQEKPEGRPS
560 570 580 590 600 610
520
pF1KE0 FAELLRAVTEIAETW
: .:::.. :..:
XP_024 FEDLLRTIDELVECEETFGR
620 630
>>NP_003206 (OMIM: 600583) tyrosine-protein kinase Tec [ (631 aa)
initn: 2038 init1: 1574 opt: 2051 Z-score: 812.6 bits: 160.3 E(92320): 1.7e-38
Smith-Waterman score: 2051; 62.6% identity (85.1% similar) in 463 aa overlap (65-525:162-624)
40 50 60 70 80 90
pF1KE0 DEELPEKYTQHRRPWLSQLSNKKQSNTGRVQPSKRKPLPPLPPSEVAEEKIQVKALYDFL
. .::.: ::.: : . . : :.:::
NP_003 CCRQTEKLAPGCEKYNLFESSIRKALPPAPETKKRRPPPPIPLEEEDNSEEIVVAMYDFQ
140 150 160 170 180 190
100 110 120 130 140 150
pF1KE0 PREPCNLALRRAEEYLILEKYNPHWWKARDRLGNEGLIPSNYVTENKITNLEIYEWYHRN
: .: :.:..::::::: . :::.:::. :::: ::::::: .: .::. :::: ::
NP_003 AAEGHDLRLERGQEYLILEKNDVHWWRARDKYGNEGYIPSNYVTGKKSNNLDQYEWYCRN
200 210 220 230 240 250
160 170 180 190 200 210
pF1KE0 ITRNQAEHLLRQESKEGAFIVRDSRHLGSYTISVFMGARRSTEAAIKHYQIKKNDSG--Q
..:..::.:::.:.:::.:.:::: . : ::.:.. ....::.::.. .. .
NP_003 MNRSKAEQLLRSEDKEGGFMVRDSSQPGLYTVSLYTKFGGEGSSGFRHYHIKETTTSPKK
260 270 280 290 300 310
220 230 240 250 260 270
pF1KE0 WYVAERHAFQSIPELIWYHQHNAAGLMTRLRYPVGLMGSCLPATAGFSYEKWEIDPSELA
.:.::.::: ::::.: ::.::::::.:::::::.. :. :.:::::::::::.::::.
NP_003 YYLAEKHAFGSIPEIIEYHKHNAAGLVTRLRYPVSVKGKNAPTTAGFSYEKWEINPSELT
320 330 340 350 360 370
280 290 300 310 320 330
pF1KE0 FIKEIGSGQFGVVHLGEWRSHIQVAIKAINEGSMSEEDFIEEAKVMMKLSHSKLVQLYGV
:..:.::: ::::.::.::.. .:::::: ::.: ::::::::::::::.: ::::::::
NP_003 FMRELGSGLFGVVRLGKWRAQYKVAIKAIREGAMCEEDFIEEAKVMMKLTHPKLVQLYGV
380 390 400 410 420 430
340 350 360 370 380 390
pF1KE0 CIQRKPLYIVTEFMENGCLLNYLRENKGKLRKEMLLSVCQDICEGMEYLERNGYIHRDLA
: :.::.:::::::: :::::.::. .:.. ...:::.:::.::::::::::..::::::
NP_003 CTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDVLLSMCQDVCEGMEYLERNSFIHRDLA
440 450 460 470 480 490
400 410 420 430 440 450
pF1KE0 ARNCLVSSTCIVKISDFGMTRYVLDDEYVSSFGAKFPIKWSPPEVFLFNKYSSKSDVWSF
::::::: . .::.:::::.::::::.:.:: :::::.:: ::::: ....:::::::::
NP_003 ARNCLVSEAGVVKVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSF
500 510 520 530 540 550
460 470 480 490 500 510
pF1KE0 GVLMWEVFTEGKMPFENKSNLQVVEAISEGFRLYRPHLAPMSIYEVMYSCWHEKPEGRPT
:::::::::::.::::. .: .:: ...: :::.:.:: .:::: ::.:::::::.
NP_003 GVLMWEVFTEGRMPFEKYTNYEVVTMVTRGHRLYQPKLASNYVYEVMLRCWQEKPEGRPS
560 570 580 590 600 610
520
pF1KE0 FAELLRAVTEIAETW
: .:::.. :..:
NP_003 FEDLLRTIDELVECEETFGR
620 630
>>XP_011512050 (OMIM: 600058) tyrosine-protein kinase TX (289 aa)
initn: 1966 init1: 1966 opt: 1966 Z-score: 783.0 bits: 153.7 E(92320): 7.7e-37
Smith-Waterman score: 1966; 100.0% identity (100.0% similar) in 289 aa overlap (239-527:1-289)
210 220 230 240 250 260
pF1KE0 DSGQWYVAERHAFQSIPELIWYHQHNAAGLMTRLRYPVGLMGSCLPATAGFSYEKWEIDP
::::::::::::::::::::::::::::::
XP_011 MTRLRYPVGLMGSCLPATAGFSYEKWEIDP
10 20 30
270 280 290 300 310 320
pF1KE0 SELAFIKEIGSGQFGVVHLGEWRSHIQVAIKAINEGSMSEEDFIEEAKVMMKLSHSKLVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SELAFIKEIGSGQFGVVHLGEWRSHIQVAIKAINEGSMSEEDFIEEAKVMMKLSHSKLVQ
40 50 60 70 80 90
330 340 350 360 370 380
pF1KE0 LYGVCIQRKPLYIVTEFMENGCLLNYLRENKGKLRKEMLLSVCQDICEGMEYLERNGYIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYGVCIQRKPLYIVTEFMENGCLLNYLRENKGKLRKEMLLSVCQDICEGMEYLERNGYIH
100 110 120 130 140 150
390 400 410 420 430 440
pF1KE0 RDLAARNCLVSSTCIVKISDFGMTRYVLDDEYVSSFGAKFPIKWSPPEVFLFNKYSSKSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDLAARNCLVSSTCIVKISDFGMTRYVLDDEYVSSFGAKFPIKWSPPEVFLFNKYSSKSD
160 170 180 190 200 210
450 460 470 480 490 500
pF1KE0 VWSFGVLMWEVFTEGKMPFENKSNLQVVEAISEGFRLYRPHLAPMSIYEVMYSCWHEKPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VWSFGVLMWEVFTEGKMPFENKSNLQVVEAISEGFRLYRPHLAPMSIYEVMYSCWHEKPE
220 230 240 250 260 270
510 520
pF1KE0 GRPTFAELLRAVTEIAETW
:::::::::::::::::::
XP_011 GRPTFAELLRAVTEIAETW
280
527 residues in 1 query sequences
64369986 residues in 92320 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Oct 24 21:57:37 2019 done: Thu Oct 24 21:57:38 2019
Total Scan time: 4.820 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]