Result of FASTA (omim) for
pF1KB7170
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7170, 439 aa
1>>>pF1KB7170 439 - 439 aa - 439 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.0928+/-0.000313; mu= 8.0029+/- 0.020
mean_var=215.4440+/-42.576, 0's: 0 Z-trim(123.6): 47 B-trim: 0 in 0/59
Lambda= 0.087379
statistics sampled from 43675 (43726) to 43675 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.794), E-opt: 0.2 (0.513), width: 16
Scan time: 10.850
The best scores are: opt bits E(85289)
NP_065168 (OMIM: 608803,608804,613206,613480) gap ( 439) 3014 392.1 1.5e-108
XP_005256977 (OMIM: 608655) PREDICTED: gap junctio ( 396) 663 95.7 2.3e-19
NP_005488 (OMIM: 608655) gap junction gamma-1 prot ( 396) 663 95.7 2.3e-19
XP_005256978 (OMIM: 608655) PREDICTED: gap junctio ( 396) 663 95.7 2.3e-19
NP_001073852 (OMIM: 608655) gap junction gamma-1 p ( 396) 663 95.7 2.3e-19
XP_011533350 (OMIM: 121015,601885) PREDICTED: gap ( 435) 471 71.5 4.9e-12
NP_068773 (OMIM: 121015,601885) gap junction alpha ( 435) 471 71.5 4.9e-12
NP_115991 (OMIM: 611924) gap junction alpha-10 pro ( 543) 455 69.6 2.3e-11
XP_011507719 (OMIM: 116200,600897,612474) PREDICTE ( 427) 452 69.1 2.5e-11
XP_011507718 (OMIM: 116200,600897,612474) PREDICTE ( 433) 452 69.1 2.5e-11
NP_005258 (OMIM: 116200,600897,612474) gap junctio ( 433) 452 69.1 2.5e-11
NP_002051 (OMIM: 121012) gap junction alpha-4 prot ( 333) 449 68.6 2.7e-11
XP_005270807 (OMIM: 121012) PREDICTED: gap junctio ( 333) 449 68.6 2.7e-11
XP_016856532 (OMIM: 121012) PREDICTED: gap junctio ( 333) 449 68.6 2.7e-11
NP_005257 (OMIM: 108770,121013,612474,614049) gap ( 358) 446 68.3 3.8e-11
NP_859054 (OMIM: 108770,121013,612474,614049) gap ( 358) 446 68.3 3.8e-11
XP_016856533 (OMIM: 108770,121013,612474,614049) P ( 358) 446 68.3 3.8e-11
XP_005273008 (OMIM: 108770,121013,612474,614049) P ( 358) 446 68.3 3.8e-11
NP_110399 (OMIM: 611923) gap junction alpha-9 prot ( 515) 434 66.9 1.4e-10
NP_065711 (OMIM: 607058) gap junction delta-2 prot ( 321) 417 64.6 4.4e-10
XP_016877927 (OMIM: 607058) PREDICTED: gap junctio ( 270) 391 61.2 3.8e-09
XP_011538981 (OMIM: 133200,605425) PREDICTED: gap ( 266) 384 60.3 6.9e-09
NP_694944 (OMIM: 133200,605425) gap junction beta- ( 266) 384 60.3 6.9e-09
XP_011533351 (OMIM: 121011,124500,148210,148350,14 ( 226) 382 60.0 7.3e-09
NP_003995 (OMIM: 121011,124500,148210,148350,14920 ( 226) 382 60.0 7.3e-09
NP_000156 (OMIM: 104100,121014,133200,164200,18610 ( 382) 385 60.6 8.1e-09
NP_940970 (OMIM: 611921) gap junction beta-7 prote ( 223) 377 59.4 1.1e-08
XP_005248773 (OMIM: 611921) PREDICTED: gap junctio ( 223) 377 59.4 1.1e-08
XP_016884897 (OMIM: 302800,304040) PREDICTED: gap ( 283) 370 58.6 2.4e-08
NP_000157 (OMIM: 302800,304040) gap junction beta- ( 283) 370 58.6 2.4e-08
XP_011529209 (OMIM: 302800,304040) PREDICTED: gap ( 283) 370 58.6 2.4e-08
NP_001091111 (OMIM: 302800,304040) gap junction be ( 283) 370 58.6 2.4e-08
NP_001103689 (OMIM: 129500,220290,304400,604418,61 ( 261) 368 58.3 2.7e-08
XP_016875849 (OMIM: 129500,220290,304400,604418,61 ( 261) 368 58.3 2.7e-08
NP_001103691 (OMIM: 129500,220290,304400,604418,61 ( 261) 368 58.3 2.7e-08
XP_016875848 (OMIM: 129500,220290,304400,604418,61 ( 261) 368 58.3 2.7e-08
NP_006774 (OMIM: 129500,220290,304400,604418,61264 ( 261) 368 58.3 2.7e-08
XP_016875846 (OMIM: 129500,220290,304400,604418,61 ( 261) 368 58.3 2.7e-08
NP_001103690 (OMIM: 129500,220290,304400,604418,61 ( 261) 368 58.3 2.7e-08
XP_016875847 (OMIM: 129500,220290,304400,604418,61 ( 261) 368 58.3 2.7e-08
NP_689343 (OMIM: 607425) gap junction delta-3 prot ( 294) 367 58.2 3.3e-08
NP_853516 (OMIM: 611925) gap junction gamma-3 prot ( 279) 366 58.1 3.4e-08
NP_005259 (OMIM: 604493) gap junction beta-5 prote ( 273) 358 57.1 6.8e-08
XP_005270808 (OMIM: 604493) PREDICTED: gap junctio ( 273) 358 57.1 6.8e-08
NP_076872 (OMIM: 133200,220290,603324,612644) gap ( 270) 357 56.9 7.3e-08
NP_001005752 (OMIM: 133200,220290,603324,612644) g ( 270) 357 56.9 7.3e-08
NP_699199 (OMIM: 611922) gap junction delta-4 prot ( 370) 350 56.2 1.7e-07
>>NP_065168 (OMIM: 608803,608804,613206,613480) gap junc (439 aa)
initn: 3014 init1: 3014 opt: 3014 Z-score: 2069.6 bits: 392.1 E(85289): 1.5e-108
Smith-Waterman score: 3014; 100.0% identity (100.0% similar) in 439 aa overlap (1-439:1-439)
10 20 30 40 50 60
pF1KB7 MTNMSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MTNMSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 PGCDNVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQERRRALRRRPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PGCDNVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQERRRALRRRPGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 RRAPRAHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGAAEGAGEEAEEAGAEEACTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 RRAPRAHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGAAEGAGEEAEEAGAEEACTK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 AVGADGKAAGTPGPTGQHDGRRRIQREGLMRVYVAQLVARAAFEVAFLVGQYLLYGFEVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 AVGADGKAAGTPGPTGQHDGRRRIQREGLMRVYVAQLVARAAFEVAFLVGQYLLYGFEVR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 PFFPCSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGLGSAQDAVRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PFFPCSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGLGSAQDAVRG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 RRGPPASAPAPAPRPPPCAFPAAAAGLACPPDYSLVVRAAERARAHDQNLANLALQALRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 RRGPPASAPAPAPRPPPCAFPAAAAGLACPPDYSLVVRAAERARAHDQNLANLALQALRD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 GAAAGDRDRDSSPCVGLPAASRGPPRAGAPASRTGSATSAGTVGEQGRPGTHERPGAKPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GAAAGDRDRDSSPCVGLPAASRGPPRAGAPASRTGSATSAGTVGEQGRPGTHERPGAKPR
370 380 390 400 410 420
430
pF1KB7 AGSEKGSASSRDGKTTVWI
:::::::::::::::::::
NP_065 AGSEKGSASSRDGKTTVWI
430
>>XP_005256977 (OMIM: 608655) PREDICTED: gap junction ga (396 aa)
initn: 1211 init1: 631 opt: 663 Z-score: 468.5 bits: 95.7 E(85289): 2.3e-19
Smith-Waterman score: 1214; 47.1% identity (68.8% similar) in 442 aa overlap (4-439:1-396)
10 20 30 40 50 60
pF1KB7 MTNMSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQ
::::::::::::::::::::::.:::::.::::::::::::.:: :::.::.:::.:
XP_005 MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQ
10 20 30 40 50
70 80 90 100 110
pF1KB7 PGCDNVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQER-RRALRRRPG
:::.::::::::::::::::::::....::::::::::.:..:. . : ..: : .:
XP_005 PGCENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPY
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 PRRAPRAHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGAAEGAGEEAEEAGAEEACT
: . : . : . .::.::. : : :.
XP_005 AMRWKQ------HRALEETEEDNEEDPMM---YPEMELESDK------------------
120 130 140 150
180 190 200 210 220 230
pF1KB7 KAVGADGKAAGTPGPTGQHDGRRRIQREGLMRVYVAQLVARAAFEVAFLVGQYLLYGFEV
..: . : : .:::::::...:::..:: ::.::..:::.::.:::.::::.:
XP_005 -----ENKEQSQPKP--KHDGRRRIREDGLMKIYVLQLLARTVFEVGFLIGQYFLYGFQV
160 170 180 190 200
240 250 260 270 280 290
pF1KB7 RPFFPCSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGLGSAQDAVR
.::. ::: :::: .:::.:::::::.:::.:: :. ::::::. :: :::.:. .:..
XP_005 HPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGLCLLLNIWEMLHLGFGTIRDSLN
210 220 230 240 250 260
300 310 320 330 340 350
pF1KB7 GRRGPPASAPAPAPRPPPCAFPAAAAGLACPPDYSLVVRAAERARAHDQNLANLALQALR
..: :. : :.: :: :...:. . . .:.: . .
XP_005 SKRRE-LEDPGAYNYPFTWNTPSA------PPGYNIAVKPDQ---IQYTELSNAKIAYKQ
270 280 290 300 310
360 370 380 390 400 410
pF1KB7 DGAAAGDRDRDSSPCVGLPAASRGPPRAGAPAS-RTGSATSAGTVGEQGRP-GTHERPG-
. : ...... .: .::: .. : :. : :..: . .:. : : .:. .
XP_005 NKANTAQEQQYGSHEENLPADLEALQREIRMAQERLDLAVQAYS--HQNNPHGPREKKAK
320 330 340 350 360 370
420 430
pF1KB7 AKPRAGSEKGSASSR--DGKTTVWI
. .:::.:..:::. ::::.:::
XP_005 VGSKAGSNKSTASSKSGDGKTSVWI
380 390
>>NP_005488 (OMIM: 608655) gap junction gamma-1 protein (396 aa)
initn: 1211 init1: 631 opt: 663 Z-score: 468.5 bits: 95.7 E(85289): 2.3e-19
Smith-Waterman score: 1214; 47.1% identity (68.8% similar) in 442 aa overlap (4-439:1-396)
10 20 30 40 50 60
pF1KB7 MTNMSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQ
::::::::::::::::::::::.:::::.::::::::::::.:: :::.::.:::.:
NP_005 MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQ
10 20 30 40 50
70 80 90 100 110
pF1KB7 PGCDNVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQER-RRALRRRPG
:::.::::::::::::::::::::....::::::::::.:..:. . : ..: : .:
NP_005 PGCENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPY
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 PRRAPRAHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGAAEGAGEEAEEAGAEEACT
: . : . : . .::.::. : : :.
NP_005 AMRWKQ------HRALEETEEDNEEDPMM---YPEMELESDK------------------
120 130 140 150
180 190 200 210 220 230
pF1KB7 KAVGADGKAAGTPGPTGQHDGRRRIQREGLMRVYVAQLVARAAFEVAFLVGQYLLYGFEV
..: . : : .:::::::...:::..:: ::.::..:::.::.:::.::::.:
NP_005 -----ENKEQSQPKP--KHDGRRRIREDGLMKIYVLQLLARTVFEVGFLIGQYFLYGFQV
160 170 180 190 200
240 250 260 270 280 290
pF1KB7 RPFFPCSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGLGSAQDAVR
.::. ::: :::: .:::.:::::::.:::.:: :. ::::::. :: :::.:. .:..
NP_005 HPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGLCLLLNIWEMLHLGFGTIRDSLN
210 220 230 240 250 260
300 310 320 330 340 350
pF1KB7 GRRGPPASAPAPAPRPPPCAFPAAAAGLACPPDYSLVVRAAERARAHDQNLANLALQALR
..: :. : :.: :: :...:. . . .:.: . .
NP_005 SKRRE-LEDPGAYNYPFTWNTPSA------PPGYNIAVKPDQ---IQYTELSNAKIAYKQ
270 280 290 300 310
360 370 380 390 400 410
pF1KB7 DGAAAGDRDRDSSPCVGLPAASRGPPRAGAPAS-RTGSATSAGTVGEQGRP-GTHERPG-
. : ...... .: .::: .. : :. : :..: . .:. : : .:. .
NP_005 NKANTAQEQQYGSHEENLPADLEALQREIRMAQERLDLAVQAYS--HQNNPHGPREKKAK
320 330 340 350 360 370
420 430
pF1KB7 AKPRAGSEKGSASSR--DGKTTVWI
. .:::.:..:::. ::::.:::
NP_005 VGSKAGSNKSTASSKSGDGKTSVWI
380 390
>>XP_005256978 (OMIM: 608655) PREDICTED: gap junction ga (396 aa)
initn: 1211 init1: 631 opt: 663 Z-score: 468.5 bits: 95.7 E(85289): 2.3e-19
Smith-Waterman score: 1214; 47.1% identity (68.8% similar) in 442 aa overlap (4-439:1-396)
10 20 30 40 50 60
pF1KB7 MTNMSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQ
::::::::::::::::::::::.:::::.::::::::::::.:: :::.::.:::.:
XP_005 MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQ
10 20 30 40 50
70 80 90 100 110
pF1KB7 PGCDNVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQER-RRALRRRPG
:::.::::::::::::::::::::....::::::::::.:..:. . : ..: : .:
XP_005 PGCENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPY
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 PRRAPRAHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGAAEGAGEEAEEAGAEEACT
: . : . : . .::.::. : : :.
XP_005 AMRWKQ------HRALEETEEDNEEDPMM---YPEMELESDK------------------
120 130 140 150
180 190 200 210 220 230
pF1KB7 KAVGADGKAAGTPGPTGQHDGRRRIQREGLMRVYVAQLVARAAFEVAFLVGQYLLYGFEV
..: . : : .:::::::...:::..:: ::.::..:::.::.:::.::::.:
XP_005 -----ENKEQSQPKP--KHDGRRRIREDGLMKIYVLQLLARTVFEVGFLIGQYFLYGFQV
160 170 180 190 200
240 250 260 270 280 290
pF1KB7 RPFFPCSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGLGSAQDAVR
.::. ::: :::: .:::.:::::::.:::.:: :. ::::::. :: :::.:. .:..
XP_005 HPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGLCLLLNIWEMLHLGFGTIRDSLN
210 220 230 240 250 260
300 310 320 330 340 350
pF1KB7 GRRGPPASAPAPAPRPPPCAFPAAAAGLACPPDYSLVVRAAERARAHDQNLANLALQALR
..: :. : :.: :: :...:. . . .:.: . .
XP_005 SKRRE-LEDPGAYNYPFTWNTPSA------PPGYNIAVKPDQ---IQYTELSNAKIAYKQ
270 280 290 300 310
360 370 380 390 400 410
pF1KB7 DGAAAGDRDRDSSPCVGLPAASRGPPRAGAPAS-RTGSATSAGTVGEQGRP-GTHERPG-
. : ...... .: .::: .. : :. : :..: . .:. : : .:. .
XP_005 NKANTAQEQQYGSHEENLPADLEALQREIRMAQERLDLAVQAYS--HQNNPHGPREKKAK
320 330 340 350 360 370
420 430
pF1KB7 AKPRAGSEKGSASSR--DGKTTVWI
. .:::.:..:::. ::::.:::
XP_005 VGSKAGSNKSTASSKSGDGKTSVWI
380 390
>>NP_001073852 (OMIM: 608655) gap junction gamma-1 prote (396 aa)
initn: 1211 init1: 631 opt: 663 Z-score: 468.5 bits: 95.7 E(85289): 2.3e-19
Smith-Waterman score: 1214; 47.1% identity (68.8% similar) in 442 aa overlap (4-439:1-396)
10 20 30 40 50 60
pF1KB7 MTNMSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQ
::::::::::::::::::::::.:::::.::::::::::::.:: :::.::.:::.:
NP_001 MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQ
10 20 30 40 50
70 80 90 100 110
pF1KB7 PGCDNVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQER-RRALRRRPG
:::.::::::::::::::::::::....::::::::::.:..:. . : ..: : .:
NP_001 PGCENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPY
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 PRRAPRAHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGAAEGAGEEAEEAGAEEACT
: . : . : . .::.::. : : :.
NP_001 AMRWKQ------HRALEETEEDNEEDPMM---YPEMELESDK------------------
120 130 140 150
180 190 200 210 220 230
pF1KB7 KAVGADGKAAGTPGPTGQHDGRRRIQREGLMRVYVAQLVARAAFEVAFLVGQYLLYGFEV
..: . : : .:::::::...:::..:: ::.::..:::.::.:::.::::.:
NP_001 -----ENKEQSQPKP--KHDGRRRIREDGLMKIYVLQLLARTVFEVGFLIGQYFLYGFQV
160 170 180 190 200
240 250 260 270 280 290
pF1KB7 RPFFPCSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGLGSAQDAVR
.::. ::: :::: .:::.:::::::.:::.:: :. ::::::. :: :::.:. .:..
NP_001 HPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGLCLLLNIWEMLHLGFGTIRDSLN
210 220 230 240 250 260
300 310 320 330 340 350
pF1KB7 GRRGPPASAPAPAPRPPPCAFPAAAAGLACPPDYSLVVRAAERARAHDQNLANLALQALR
..: :. : :.: :: :...:. . . .:.: . .
NP_001 SKRRE-LEDPGAYNYPFTWNTPSA------PPGYNIAVKPDQ---IQYTELSNAKIAYKQ
270 280 290 300 310
360 370 380 390 400 410
pF1KB7 DGAAAGDRDRDSSPCVGLPAASRGPPRAGAPAS-RTGSATSAGTVGEQGRP-GTHERPG-
. : ...... .: .::: .. : :. : :..: . .:. : : .:. .
NP_001 NKANTAQEQQYGSHEENLPADLEALQREIRMAQERLDLAVQAYS--HQNNPHGPREKKAK
320 330 340 350 360 370
420 430
pF1KB7 AKPRAGSEKGSASSR--DGKTTVWI
. .:::.:..:::. ::::.:::
NP_001 VGSKAGSNKSTASSKSGDGKTSVWI
380 390
>>XP_011533350 (OMIM: 121015,601885) PREDICTED: gap junc (435 aa)
initn: 865 init1: 438 opt: 471 Z-score: 337.1 bits: 71.5 E(85289): 4.9e-12
Smith-Waterman score: 839; 36.4% identity (59.3% similar) in 450 aa overlap (6-433:4-384)
10 20 30 40 50 60
pF1KB7 MTNMSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQ
:::: ::::. ..::: .:::::::: .:::.. ....: ...:::. :::::.:
XP_011 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQ
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 PGCDNVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQERRRALRRRPGP
:::.::::: :.::.:::..::. .:::...:::...: ..: :....: ...
XP_011 PGCENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLH-IVRMEEKKKERE-EEEQLK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 RRAPRAHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGAAEGAGEEAEEAGAEEACTK
:..: . :: ...:
XP_011 RESPSPKEPP------------QDNP----------------------------------
120 130
190 200 210 220 230
pF1KB7 AVGADGKAAGTPGPTGQHDGRRRIQREG-LMRVYVAQLVARAAFEVAFLVGQYLLYGFEV
...: : :.. : :.:.:: ... .. :::.:..:::.:::::.
XP_011 ---------------SSRDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFEL
140 150 160 170
240 250 260 270 280 290
pF1KB7 RPFFPCSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGLGSAQDAVR
.:.. :.: :::..::::.:::::::.:.. : .:.: ::::. :. ::: . ...:
XP_011 KPLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVT
180 190 200 210 220 230
300 310 320 330 340
pF1KB7 GRRGPPAS-APA----PAPRPPPCAFPAAAAGLACPPDYSLVVRAAERARA-----HDQN
.: :: :: :: : : :: ::.: :. :: :. .. .:::
XP_011 SRLGPDASEAPLGTADPPPLPPSSRPPAVAIGF--PPYYAHTAAPLGQARAVGYPGAPPP
240 250 260 270 280 290
350 360 370 380 390
pF1KB7 LANLALQALRDGAAAGDRDRDSSPCVGL---------PAASRGPPRAGA-PASRTGSATS
:.. : :: .. . :. . . : :: : :: : ::. : .: :
XP_011 AADFKLLALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQPPALKAYPAASTPAAPS
300 310 320 330 340 350
400 410 420 430
pF1KB7 AGTVGEQGRPGTHE-RPGAKPRAGSEKGSASSRDGKTTVWI
:: .. : .:: . :: : . ::.:: .:
XP_011 P--VGSSSPPLAHEAEAGAAPLLLD--GSGSSLEGSALAGTPEEEEQAVTTAAQMHQPPL
360 370 380 390 400
XP_011 PLGDPGRASKASRASSGRARPEDLAI
410 420 430
>>NP_068773 (OMIM: 121015,601885) gap junction alpha-3 p (435 aa)
initn: 865 init1: 438 opt: 471 Z-score: 337.1 bits: 71.5 E(85289): 4.9e-12
Smith-Waterman score: 839; 36.4% identity (59.3% similar) in 450 aa overlap (6-433:4-384)
10 20 30 40 50 60
pF1KB7 MTNMSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQ
:::: ::::. ..::: .:::::::: .:::.. ....: ...:::. :::::.:
NP_068 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQ
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 PGCDNVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQERRRALRRRPGP
:::.::::: :.::.:::..::. .:::...:::...: ..: :....: ...
NP_068 PGCENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLH-IVRMEEKKKERE-EEEQLK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 RRAPRAHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGAAEGAGEEAEEAGAEEACTK
:..: . :: ...:
NP_068 RESPSPKEPP------------QDNP----------------------------------
120 130
190 200 210 220 230
pF1KB7 AVGADGKAAGTPGPTGQHDGRRRIQREG-LMRVYVAQLVARAAFEVAFLVGQYLLYGFEV
...: : :.. : :.:.:: ... .. :::.:..:::.:::::.
NP_068 ---------------SSRDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFEL
140 150 160 170
240 250 260 270 280 290
pF1KB7 RPFFPCSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGLGSAQDAVR
.:.. :.: :::..::::.:::::::.:.. : .:.: ::::. :. ::: . ...:
NP_068 KPLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVT
180 190 200 210 220 230
300 310 320 330 340
pF1KB7 GRRGPPAS-APA----PAPRPPPCAFPAAAAGLACPPDYSLVVRAAERARA-----HDQN
.: :: :: :: : : :: ::.: :. :: :. .. .:::
NP_068 SRLGPDASEAPLGTADPPPLPPSSRPPAVAIGF--PPYYAHTAAPLGQARAVGYPGAPPP
240 250 260 270 280 290
350 360 370 380 390
pF1KB7 LANLALQALRDGAAAGDRDRDSSPCVGL---------PAASRGPPRAGA-PASRTGSATS
:.. : :: .. . :. . . : :: : :: : ::. : .: :
NP_068 AADFKLLALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQPPALKAYPAASTPAAPS
300 310 320 330 340 350
400 410 420 430
pF1KB7 AGTVGEQGRPGTHE-RPGAKPRAGSEKGSASSRDGKTTVWI
:: .. : .:: . :: : . ::.:: .:
NP_068 P--VGSSSPPLAHEAEAGAAPLLLD--GSGSSLEGSALAGTPEEEEQAVTTAAQMHQPPL
360 370 380 390 400
NP_068 PLGDPGRASKASRASSGRARPEDLAI
410 420 430
>>NP_115991 (OMIM: 611924) gap junction alpha-10 protein (543 aa)
initn: 786 init1: 420 opt: 455 Z-score: 325.0 bits: 69.6 E(85289): 2.3e-11
Smith-Waterman score: 713; 36.9% identity (64.1% similar) in 309 aa overlap (6-305:4-258)
10 20 30 40 50 60
pF1KB7 MTNMSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQ
:..: .:::.:.:::.:::.:::.: .::... :..: ...:::. :.:::::
NP_115 MGDWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQ
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 PGCDNVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQERRRALRRRPGP
:::.:.::: :.: .::::.::. .:.::..:.:.:..:: :: :..:.:
NP_115 PGCNNICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRL-RAFEKDRQRK-------
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 RRAPRAHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGAAEGAGEEAEEAGAEEACTK
. ::.. : : . .: : . ::... . : :
NP_115 KSHLRAQMENPDLDLEEQQRIDRE-----LRRLEEQKRIHKVPLKG-----------C--
120 130 140 150
190 200 210 220 230 240
pF1KB7 AVGADGKAAGTPGPTGQHDGRRRIQREGLMRVYVAQLVARAAFEVAFLVGQYLLYGFEVR
:.:.:: ....:...::.:..:::.::::...
NP_115 ----------------------------LLRTYVLHILTRSVLEVGFMIGQYILYGFQMH
160 170 180
250 260 270 280 290
pF1KB7 PFFPCSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGL---------
:.. :.. :::..::::::::::::.:.: :. .. . ::::. :. :::.
NP_115 PLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMRTLYK
190 200 210 220 230 240
300 310 320 330 340 350
pF1KB7 GSAQDAVRGRRGPPASAPAPAPRPPPCAFPAAAAGLACPPDYSLVVRAAERARAHDQNLA
:...... . :::
NP_115 KSSSEGIEDETGPPFHLKKYSVAQQCMICSSLPERISPLQANNQQQVIRVNVPKSKTMWQ
250 260 270 280 290 300
>>XP_011507719 (OMIM: 116200,600897,612474) PREDICTED: g (427 aa)
initn: 795 init1: 450 opt: 452 Z-score: 324.3 bits: 69.1 E(85289): 2.5e-11
Smith-Waterman score: 737; 33.6% identity (59.3% similar) in 425 aa overlap (6-428:4-353)
10 20 30 40 50 60
pF1KB7 MTNMSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQ
:::: .:::...::: .:.:::::: .:::.. ....: ...:::. :.:::.:
XP_011 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQ
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 PGCDNVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQERRRALRRRPGP
:::.::::: :.::.:.::.::. .::::.::.:.::: . : :... :
XP_011 PGCENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYV-RMEEKRKSR--------
60 70 80 90 100
130 140 150 160 170 180
pF1KB7 RRAPRAHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGAAEGAGEEAEEAGAEEACTK
: :: : :.. .: ... .:
XP_011 ----------------------------------EAEELGQQAGTN-----GGPDQGSVK
110 120 130
190 200 210 220 230
pF1KB7 AVGADGKAAGTPGPTGQHDGRRRIQREG-LMRVYVAQLVARAAFEVAFLVGQYLLYGFEV
:..:. : .... :: :.:.:. ... .. :::.:.::.:.::::..
XP_011 ------KSSGSKGT-------KKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRI
140 150 160 170
240 250 260 270 280 290
pF1KB7 RPFFPCSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGLGSAQDAVR
:.. ::: :::.:::::::::::::.:.: : :. . :.::. :..:::: . ..:..
XP_011 LPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALK
180 190 200 210 220 230
300 310 320 330 340 350
pF1KB7 GRRGPPASAPAPAPRPPPCAFPAAAAGLACPPDYSLVVRAAERARAHDQNLANLALQALR
: :. : . : :.... :.:. :. .: :.....
XP_011 -R---PVEQPL-GEIPEKSLHSIAVSSIQKAKGYQLL--EEEKIVSHYFPLTEVGMVETS
240 250 260 270 280 290
360 370 380 390 400 410
pF1KB7 DGAAAGDRDRDSSPCVG-LPAASRGPPRAGAPASRTGSATSAGTVGEQGRPGTHERPGAK
: . . . .: : ::: .. ...:. : .: :. . ::.
XP_011 PLPAKPFNQFEEKISTGPLGDLSRGYQETLPSYAQVGAQEVEG----EGPPA---EEGAE
300 310 320 330 340
420 430
pF1KB7 PRAGSEKGSASSRDGKTTVWI
:..: .: :
XP_011 PEVGEKKEEAERLTTEEQEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPS
350 360 370 380 390 400
>>XP_011507718 (OMIM: 116200,600897,612474) PREDICTED: g (433 aa)
initn: 795 init1: 450 opt: 452 Z-score: 324.2 bits: 69.1 E(85289): 2.5e-11
Smith-Waterman score: 737; 33.6% identity (59.3% similar) in 425 aa overlap (6-428:4-353)
10 20 30 40 50 60
pF1KB7 MTNMSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQ
:::: .:::...::: .:.:::::: .:::.. ....: ...:::. :.:::.:
XP_011 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQ
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 PGCDNVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQERRRALRRRPGP
:::.::::: :.::.:.::.::. .::::.::.:.::: . : :... :
XP_011 PGCENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYV-RMEEKRKSR--------
60 70 80 90 100
130 140 150 160 170 180
pF1KB7 RRAPRAHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGAAEGAGEEAEEAGAEEACTK
: :: : :.. .: ... .:
XP_011 ----------------------------------EAEELGQQAGTN-----GGPDQGSVK
110 120 130
190 200 210 220 230
pF1KB7 AVGADGKAAGTPGPTGQHDGRRRIQREG-LMRVYVAQLVARAAFEVAFLVGQYLLYGFEV
:..:. : .... :: :.:.:. ... .. :::.:.::.:.::::..
XP_011 ------KSSGSKGT-------KKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRI
140 150 160 170
240 250 260 270 280 290
pF1KB7 RPFFPCSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGLGSAQDAVR
:.. ::: :::.:::::::::::::.:.: : :. . :.::. :..:::: . ..:..
XP_011 LPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALK
180 190 200 210 220 230
300 310 320 330 340 350
pF1KB7 GRRGPPASAPAPAPRPPPCAFPAAAAGLACPPDYSLVVRAAERARAHDQNLANLALQALR
: :. : . : :.... :.:. :. .: :.....
XP_011 -R---PVEQPL-GEIPEKSLHSIAVSSIQKAKGYQLL--EEEKIVSHYFPLTEVGMVETS
240 250 260 270 280 290
360 370 380 390 400 410
pF1KB7 DGAAAGDRDRDSSPCVG-LPAASRGPPRAGAPASRTGSATSAGTVGEQGRPGTHERPGAK
: . . . .: : ::: .. ...:. : .: :. . ::.
XP_011 PLPAKPFNQFEEKISTGPLGDLSRGYQETLPSYAQVGAQEVEG----EGPPA---EEGAE
300 310 320 330 340
420 430
pF1KB7 PRAGSEKGSASSRDGKTTVWI
:..: .: :
XP_011 PEVGEKKEEAERLTTEEQEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPS
350 360 370 380 390 400
439 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 19:55:09 2016 done: Mon Nov 7 19:55:11 2016
Total Scan time: 10.850 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]