Result of FASTA (omim) for pF1KE0686
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0686, 400 aa
  1>>>pF1KE0686     400 - 400 aa - 400 aa
Library: /omim/omim.rfq.tfa
  64369986 residues in 92320 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 12.2826+/-0.000446; mu= -11.3996+/- 0.028
 mean_var=651.3030+/-138.115, 0's: 0 Z-trim(125.0): 1313  B-trim: 0 in 0/53
 Lambda= 0.050255
 statistics sampled from 47974 (49651) to 47974 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.798), E-opt: 0.2 (0.538), width:  16
 Scan time:  4.760

The best scores are:                                      opt bits E(92320)
NP_116584 (OMIM: 602006) MAP kinase-activated prot ( 400) 2729 212.4 1.7e-54
NP_004750 (OMIM: 602006) MAP kinase-activated prot ( 370) 2448 192.0 2.3e-48
XP_005273410 (OMIM: 602006) MAP kinase-activated p ( 371) 2448 192.0 2.3e-48
XP_016858299 (OMIM: 602006) MAP kinase-activated p ( 307) 2067 164.2 4.2e-40
NP_004626 (OMIM: 602130,617111) MAP kinase-activat ( 382) 1762 142.2 2.2e-33
NP_001230855 (OMIM: 602130,617111) MAP kinase-acti ( 382) 1762 142.2 2.2e-33
NP_001230854 (OMIM: 602130,617111) MAP kinase-acti ( 382) 1762 142.2 2.2e-33
XP_024304639 (OMIM: 601684) ribosomal protein S6 k ( 643)  697 65.3 5.2e-10
NP_001317370 (OMIM: 601684) ribosomal protein S6 k ( 719)  697 65.4 5.6e-10
NP_002944 (OMIM: 601684) ribosomal protein S6 kina ( 735)  697 65.4 5.7e-10
NP_001006666 (OMIM: 601684) ribosomal protein S6 k ( 744)  697 65.4 5.7e-10
NP_003647 (OMIM: 604998) calcium/calmodulin-depend ( 370)  652 61.7 3.6e-09
XP_005265573 (OMIM: 604998) calcium/calmodulin-dep ( 413)  652 61.8 3.8e-09
NP_001735 (OMIM: 114080) calcium/calmodulin-depend ( 473)  642 61.1 6.8e-09
NP_001310303 (OMIM: 114080) calcium/calmodulin-dep ( 473)  642 61.1 6.8e-09
NP_001310304 (OMIM: 114080) calcium/calmodulin-dep ( 473)  642 61.1 6.8e-09
XP_005274634 (OMIM: 300075,300844,303600) ribosoma ( 710)  646 61.7 7.2e-09
XP_006724570 (OMIM: 300075,300844,303600) ribosoma ( 711)  646 61.7 7.2e-09
XP_016885208 (OMIM: 300075,300844,303600) ribosoma ( 711)  646 61.7 7.2e-09
XP_005274630 (OMIM: 300075,300844,303600) ribosoma ( 739)  646 61.7 7.4e-09
XP_011543858 (OMIM: 300075,300844,303600) ribosoma ( 745)  646 61.7 7.4e-09
NP_065172 (OMIM: 614994) calcium/calmodulin-depend ( 476)  637 60.8 8.8e-09
XP_016857355 (OMIM: 614994) calcium/calmodulin-dep ( 476)  637 60.8 8.8e-09
XP_006717545 (OMIM: 607957) calcium/calmodulin-dep ( 362)  629 60.1 1.1e-08
XP_016885207 (OMIM: 300075,300844,303600) ribosoma ( 711)  635 60.9 1.3e-08
XP_016885204 (OMIM: 300075,300844,303600) ribosoma ( 712)  635 60.9 1.3e-08
XP_016885206 (OMIM: 300075,300844,303600) ribosoma ( 712)  635 60.9 1.3e-08
XP_016885205 (OMIM: 300075,300844,303600) ribosoma ( 712)  635 60.9 1.3e-08
XP_011543865 (OMIM: 300075,300844,303600) ribosoma ( 712)  635 60.9 1.3e-08
XP_016885202 (OMIM: 300075,300844,303600) ribosoma ( 712)  635 60.9 1.3e-08
XP_016885203 (OMIM: 300075,300844,303600) ribosoma ( 712)  635 60.9 1.3e-08
XP_011543864 (OMIM: 300075,300844,303600) ribosoma ( 717)  635 60.9 1.3e-08
XP_011543860 (OMIM: 300075,300844,303600) ribosoma ( 718)  635 60.9 1.3e-08
XP_011543859 (OMIM: 300075,300844,303600) ribosoma ( 718)  635 60.9 1.3e-08
XP_011543863 (OMIM: 300075,300844,303600) ribosoma ( 718)  635 60.9 1.3e-08
XP_011543862 (OMIM: 300075,300844,303600) ribosoma ( 718)  635 60.9 1.3e-08
XP_006717546 (OMIM: 607957) calcium/calmodulin-dep ( 355)  626 59.8 1.3e-08
NP_004577 (OMIM: 300075,300844,303600) ribosomal p ( 740)  635 60.9 1.3e-08
NP_065130 (OMIM: 607957) calcium/calmodulin-depend ( 357)  626 59.8 1.3e-08
XP_011543857 (OMIM: 300075,300844,303600) ribosoma ( 746)  635 60.9 1.3e-08
NP_705718 (OMIM: 607957) calcium/calmodulin-depend ( 385)  626 59.9 1.3e-08
XP_024309564 (OMIM: 604998) calcium/calmodulin-dep ( 308)  619 59.2 1.7e-08
XP_016862843 (OMIM: 604998) calcium/calmodulin-dep ( 326)  619 59.3 1.7e-08
XP_005265574 (OMIM: 604998) calcium/calmodulin-dep ( 369)  619 59.3 1.9e-08
NP_001305866 (OMIM: 601685) ribosomal protein S6 k ( 635)  619 59.6 2.6e-08
NP_001305867 (OMIM: 601685) ribosomal protein S6 k ( 644)  619 59.6 2.6e-08
XP_011517893 (OMIM: 607957) calcium/calmodulin-dep ( 372)  612 58.8 2.7e-08
NP_001034671 (OMIM: 300680) calcium/calmodulin-dep ( 426)  613 59.0 2.8e-08
XP_011517895 (OMIM: 607957) calcium/calmodulin-dep ( 311)  609 58.5 2.8e-08
XP_011517894 (OMIM: 607957) calcium/calmodulin-dep ( 315)  609 58.5 2.8e-08


>>NP_116584 (OMIM: 602006) MAP kinase-activated protein   (400 aa)
 initn: 2729 init1: 2729 opt: 2729  Z-score: 1099.8  bits: 212.4 E(92320): 1.7e-54
Smith-Waterman score: 2729; 100.0% identity (100.0% similar) in 400 aa overlap (1-400:1-400)

               10        20        30        40        50        60
pF1KE0 MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAII
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 DDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 DDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 VDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 VDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 NIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 NIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 DKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 DKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 LIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 LIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSAL
              310       320       330       340       350       360

              370       380       390       400
pF1KE0 ATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH
       ::::::::::::::::::::::::::::::::::::::::
NP_116 ATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH
              370       380       390       400

>>NP_004750 (OMIM: 602006) MAP kinase-activated protein   (370 aa)
 initn: 2448 init1: 2448 opt: 2448  Z-score: 990.1  bits: 192.0 E(92320): 2.3e-48
Smith-Waterman score: 2448; 100.0% identity (100.0% similar) in 353 aa overlap (1-353:1-353)

               10        20        30        40        50        60
pF1KE0 MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAII
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 DDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 VDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 NIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 DKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 LIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSAL
       :::::::::::::::::::::::::::::::::::::::::::::::::::::       
NP_004 LIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKGCLHDKN
              310       320       330       340       350       360

              370       380       390       400
pF1KE0 ATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH
                                               
NP_004 SDQATWLTRL                              
              370                              

>>XP_005273410 (OMIM: 602006) MAP kinase-activated prote  (371 aa)
 initn: 2448 init1: 2448 opt: 2448  Z-score: 990.1  bits: 192.0 E(92320): 2.3e-48
Smith-Waterman score: 2448; 100.0% identity (100.0% similar) in 353 aa overlap (1-353:1-353)

               10        20        30        40        50        60
pF1KE0 MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAII
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 DDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 VDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 NIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 DKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 LIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSAL
       :::::::::::::::::::::::::::::::::::::::::::::::::::::       
XP_005 LIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKGCLHDKN
              310       320       330       340       350       360

              370       380       390       400
pF1KE0 ATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH
                                               
XP_005 SDQATWLTRRR                             
              370                              

>>XP_016858299 (OMIM: 602006) MAP kinase-activated prote  (307 aa)
 initn: 2067 init1: 2067 opt: 2067  Z-score: 841.7  bits: 164.2 E(92320): 4.2e-40
Smith-Waterman score: 2067; 100.0% identity (100.0% similar) in 307 aa overlap (94-400:1-307)

            70        80        90       100       110       120   
pF1KE0 KVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDV
                                     ::::::::::::::::::::::::::::::
XP_016                               MLQDCPKARREVELHWRASQCPHIVRIVDV
                                             10        20        30

           130       140       150       160       170       180   
pF1KE0 YENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIA
               40        50        60        70        80        90

           190       200       210       220       230       240   
pF1KE0 HRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKS
              100       110       120       130       140       150

           250       260       270       280       290       300   
pF1KE0 CDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIR
              160       170       180       190       200       210

           310       320       330       340       350       360   
pF1KE0 NLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATM
              220       230       240       250       260       270

           370       380       390       400
pF1KE0 RVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH
       :::::::::::::::::::::::::::::::::::::
XP_016 RVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH
              280       290       300       

>>NP_004626 (OMIM: 602130,617111) MAP kinase-activated p  (382 aa)
 initn: 1017 init1: 972 opt: 1762  Z-score: 721.1  bits: 142.2 E(92320): 2.2e-33
Smith-Waterman score: 1768; 70.7% identity (86.2% similar) in 369 aa overlap (21-389:12-368)

               10        20        30        40        50        60
pF1KE0 MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAII
                           : :: :. :  :.    :  .. :          :: :. 
NP_004          MDGETAEEQGGPVPP-PVAPGGPGLGGAPGGRREP----------KKYAVT
                        10         20        30                  40

               70        80        90       100       110       120
pF1KE0 DDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRI
       :::....::::::.:::::. :..:: .: :::.: : ::::.::. ::.::  :::: :
NP_004 DDYQLSKQVLGLGVNGKVLECFHRRTGQKCALKLLYDSPKARQEVDHHWQASGGPHIVCI
               50        60        70        80        90       100

              130       140       150       160       170       180
pF1KE0 VDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSI
       .:::::.. :..::::.:::..:::::::::.:::::::::::.:::..:: :::.::: 
NP_004 LDVYENMHHGKRCLLIIMECMEGGELFSRIQERGDQAFTEREAAEIMRDIGTAIQFLHSH
              110       120       130       140       150       160

              190       200       210       220       230       240
pF1KE0 NIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKY
       :::::::::::::::::. .:.::::::::::::: .:.: :::::::::::::::::::
NP_004 NIAHRDVKPENLLYTSKEKDAVLKLTDFGFAKETT-QNALQTPCYTPYYVAPEVLGPEKY
              170       180       190        200       210         

              250       260       270       280       290       300
pF1KE0 DKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKM
       :::::::::::::::::::.:::::: : ::::::: :::.::: :::::::::::..:.
NP_004 DKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYGFPNPEWSEVSEDAKQ
     220       230       240       250       260       270         

              310       320       330       340       350       360
pF1KE0 LIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSAL
       ::: ::::.::.:.:::.::::::: ::  ::::::::.:::.:::..:..:::::::::
NP_004 LIRLLLKTDPTERLTITQFMNHPWINQSMVVPQTPLHTARVLQEDKDHWDEVKEEMTSAL
     280       290       300       310       320       330         

              370       380       390       400   
pF1KE0 ATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH   
       :::::::.:.::: .. ..: :: :::::              
NP_004 ATMRVDYDQVKIKDLKTSNNRLLNKRRKKQAGSSSASQGCNNQ
     340       350       360       370       380  

>>NP_001230855 (OMIM: 602130,617111) MAP kinase-activate  (382 aa)
 initn: 1017 init1: 972 opt: 1762  Z-score: 721.1  bits: 142.2 E(92320): 2.2e-33
Smith-Waterman score: 1768; 70.7% identity (86.2% similar) in 369 aa overlap (21-389:12-368)

               10        20        30        40        50        60
pF1KE0 MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAII
                           : :: :. :  :.    :  .. :          :: :. 
NP_001          MDGETAEEQGGPVPP-PVAPGGPGLGGAPGGRREP----------KKYAVT
                        10         20        30                  40

               70        80        90       100       110       120
pF1KE0 DDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRI
       :::....::::::.:::::. :..:: .: :::.: : ::::.::. ::.::  :::: :
NP_001 DDYQLSKQVLGLGVNGKVLECFHRRTGQKCALKLLYDSPKARQEVDHHWQASGGPHIVCI
               50        60        70        80        90       100

              130       140       150       160       170       180
pF1KE0 VDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSI
       .:::::.. :..::::.:::..:::::::::.:::::::::::.:::..:: :::.::: 
NP_001 LDVYENMHHGKRCLLIIMECMEGGELFSRIQERGDQAFTEREAAEIMRDIGTAIQFLHSH
              110       120       130       140       150       160

              190       200       210       220       230       240
pF1KE0 NIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKY
       :::::::::::::::::. .:.::::::::::::: .:.: :::::::::::::::::::
NP_001 NIAHRDVKPENLLYTSKEKDAVLKLTDFGFAKETT-QNALQTPCYTPYYVAPEVLGPEKY
              170       180       190        200       210         

              250       260       270       280       290       300
pF1KE0 DKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKM
       :::::::::::::::::::.:::::: : ::::::: :::.::: :::::::::::..:.
NP_001 DKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYGFPNPEWSEVSEDAKQ
     220       230       240       250       260       270         

              310       320       330       340       350       360
pF1KE0 LIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSAL
       ::: ::::.::.:.:::.::::::: ::  ::::::::.:::.:::..:..:::::::::
NP_001 LIRLLLKTDPTERLTITQFMNHPWINQSMVVPQTPLHTARVLQEDKDHWDEVKEEMTSAL
     280       290       300       310       320       330         

              370       380       390       400   
pF1KE0 ATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH   
       :::::::.:.::: .. ..: :: :::::              
NP_001 ATMRVDYDQVKIKDLKTSNNRLLNKRRKKQAGSSSASQGCNNQ
     340       350       360       370       380  

>>NP_001230854 (OMIM: 602130,617111) MAP kinase-activate  (382 aa)
 initn: 1017 init1: 972 opt: 1762  Z-score: 721.1  bits: 142.2 E(92320): 2.2e-33
Smith-Waterman score: 1768; 70.7% identity (86.2% similar) in 369 aa overlap (21-389:12-368)

               10        20        30        40        50        60
pF1KE0 MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAII
                           : :: :. :  :.    :  .. :          :: :. 
NP_001          MDGETAEEQGGPVPP-PVAPGGPGLGGAPGGRREP----------KKYAVT
                        10         20        30                  40

               70        80        90       100       110       120
pF1KE0 DDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRI
       :::....::::::.:::::. :..:: .: :::.: : ::::.::. ::.::  :::: :
NP_001 DDYQLSKQVLGLGVNGKVLECFHRRTGQKCALKLLYDSPKARQEVDHHWQASGGPHIVCI
               50        60        70        80        90       100

              130       140       150       160       170       180
pF1KE0 VDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSI
       .:::::.. :..::::.:::..:::::::::.:::::::::::.:::..:: :::.::: 
NP_001 LDVYENMHHGKRCLLIIMECMEGGELFSRIQERGDQAFTEREAAEIMRDIGTAIQFLHSH
              110       120       130       140       150       160

              190       200       210       220       230       240
pF1KE0 NIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKY
       :::::::::::::::::. .:.::::::::::::: .:.: :::::::::::::::::::
NP_001 NIAHRDVKPENLLYTSKEKDAVLKLTDFGFAKETT-QNALQTPCYTPYYVAPEVLGPEKY
              170       180       190        200       210         

              250       260       270       280       290       300
pF1KE0 DKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKM
       :::::::::::::::::::.:::::: : ::::::: :::.::: :::::::::::..:.
NP_001 DKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYGFPNPEWSEVSEDAKQ
     220       230       240       250       260       270         

              310       320       330       340       350       360
pF1KE0 LIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSAL
       ::: ::::.::.:.:::.::::::: ::  ::::::::.:::.:::..:..:::::::::
NP_001 LIRLLLKTDPTERLTITQFMNHPWINQSMVVPQTPLHTARVLQEDKDHWDEVKEEMTSAL
     280       290       300       310       320       330         

              370       380       390       400   
pF1KE0 ATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH   
       :::::::.:.::: .. ..: :: :::::              
NP_001 ATMRVDYDQVKIKDLKTSNNRLLNKRRKKQAGSSSASQGCNNQ
     340       350       360       370       380  

>>XP_024304639 (OMIM: 601684) ribosomal protein S6 kinas  (643 aa)
 initn: 596 init1: 206 opt: 697  Z-score: 301.3  bits: 65.3 E(92320): 5.2e-10
Smith-Waterman score: 703; 34.2% identity (66.9% similar) in 366 aa overlap (37-398:301-643)

         10        20        30        40        50        60      
pF1KE0 GQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVT
                                     :  ::  :   : . :.  :: ...:  :.
XP_024 SPGIPPSAGAHQLFRGFSFVATGLMEDDGKPRAPQA-PLHSVVQQLH-GKNLVFSDGYVV
              280       290       300        310        320        

         70        80        90       100        110       120     
pF1KE0 SQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPK-ARREVELHWRASQCPHIVRIVDVYE
       ....:.:  ..  .  .: :. ..:.:...   .   .:.:.  : .: :.:. . :::.
XP_024 KETIGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPSEEIEILLRYGQHPNIITLKDVYD
      330       340       350       360       370       380        

         130       140       150       160       170       180     
pF1KE0 NLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHR
       .   :..  :.. : . ::::...:  .  . :.::::: ....::....:::: ...::
XP_024 D---GKHVYLVT-ELMRGGELLDKILRQ--KFFSEREASFVLHTIGKTVEYLHSQGVVHR
         390        400       410         420       430       440  

         190       200        210       220        230       240   
pF1KE0 DVKPENLLYTSKRPNA-ILKLTDFGFAKETTSHNSLT-TPCYTPYYVAPEVLGPEKYDKS
       :.:: :.::...  :   :.. ::::::.  ..:.:  :::::  .::::::  . ::..
XP_024 DLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEG
            450       460       470       480       490       500  

           250       260       270        280       290       300  
pF1KE0 CDMWSLGVIMYILLCGYPPFYSNHGLAISPG-MKTRIRMGQYEFPNPEWSEVSEEVKMLI
       ::.::::...: .: :: ::   .: . .:  . :::  :.. . . .:. ::: .: :.
XP_024 CDIWSLGILLYTMLAGYTPF--ANGPSDTPEEILTRIGSGKFTLSGGNWNTVSETAKDLV
            510       520         530       540       550       560

            310       320       330       340       350       360  
pF1KE0 RNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALAT
        ..:...: ::.:  . ..:::. :. :.::. :        ...  . ::  :... ..
XP_024 SKMLHVDPHQRLTAKQVLQHPWVTQKDKLPQSQL--------SHQDLQLVKGAMAATYSA
              570       580       590               600       610  

            370       380       390       400
pF1KE0 MRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH
       .  .    ..: ::..   .: .::  .: : ...:  
XP_024 LNSSKPTPQLKPIESS---ILAQRR--VRKLPSTTL  
            620          630         640     

>>NP_001317370 (OMIM: 601684) ribosomal protein S6 kinas  (719 aa)
 initn: 623 init1: 206 opt: 697  Z-score: 300.8  bits: 65.4 E(92320): 5.6e-10
Smith-Waterman score: 703; 34.2% identity (66.9% similar) in 366 aa overlap (37-398:377-719)

         10        20        30        40        50        60      
pF1KE0 GQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVT
                                     :  ::  :   : . :.  :: ...:  :.
NP_001 SPGIPPSAGAHQLFRGFSFVATGLMEDDGKPRAPQA-PLHSVVQQLH-GKNLVFSDGYVV
        350       360       370       380        390        400    

         70        80        90       100        110       120     
pF1KE0 SQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPK-ARREVELHWRASQCPHIVRIVDVYE
       ....:.:  ..  .  .: :. ..:.:...   .   .:.:.  : .: :.:. . :::.
NP_001 KETIGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPSEEIEILLRYGQHPNIITLKDVYD
          410       420       430       440       450       460    

         130       140       150       160       170       180     
pF1KE0 NLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHR
       .   :..  :.. : . ::::...:  .  . :.::::: ....::....:::: ...::
NP_001 D---GKHVYLVT-ELMRGGELLDKILRQ--KFFSEREASFVLHTIGKTVEYLHSQGVVHR
             470        480         490       500       510        

         190       200        210       220        230       240   
pF1KE0 DVKPENLLYTSKRPNA-ILKLTDFGFAKETTSHNSLT-TPCYTPYYVAPEVLGPEKYDKS
       :.:: :.::...  :   :.. ::::::.  ..:.:  :::::  .::::::  . ::..
NP_001 DLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEG
      520       530       540       550       560       570        

           250       260       270        280       290       300  
pF1KE0 CDMWSLGVIMYILLCGYPPFYSNHGLAISPG-MKTRIRMGQYEFPNPEWSEVSEEVKMLI
       ::.::::...: .: :: ::   .: . .:  . :::  :.. . . .:. ::: .: :.
NP_001 CDIWSLGILLYTMLAGYTPF--ANGPSDTPEEILTRIGSGKFTLSGGNWNTVSETAKDLV
      580       590         600       610       620       630      

            310       320       330       340       350       360  
pF1KE0 RNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALAT
        ..:...: ::.:  . ..:::. :. :.::. :        ...  . ::  :... ..
NP_001 SKMLHVDPHQRLTAKQVLQHPWVTQKDKLPQSQL--------SHQDLQLVKGAMAATYSA
        640       650       660       670               680        

            370       380       390       400
pF1KE0 MRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH
       .  .    ..: ::..   .: .::  .: : ...:  
NP_001 LNSSKPTPQLKPIESS---ILAQRR--VRKLPSTTL  
      690       700          710             

>>NP_002944 (OMIM: 601684) ribosomal protein S6 kinase a  (735 aa)
 initn: 623 init1: 206 opt: 697  Z-score: 300.7  bits: 65.4 E(92320): 5.7e-10
Smith-Waterman score: 703; 34.2% identity (66.9% similar) in 366 aa overlap (37-398:393-735)

         10        20        30        40        50        60      
pF1KE0 GQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVT
                                     :  ::  :   : . :.  :: ...:  :.
NP_002 SPGIPPSAGAHQLFRGFSFVATGLMEDDGKPRAPQA-PLHSVVQQLH-GKNLVFSDGYVV
            370       380       390        400        410       420

         70        80        90       100        110       120     
pF1KE0 SQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPK-ARREVELHWRASQCPHIVRIVDVYE
       ....:.:  ..  .  .: :. ..:.:...   .   .:.:.  : .: :.:. . :::.
NP_002 KETIGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPSEEIEILLRYGQHPNIITLKDVYD
              430       440       450       460       470       480

         130       140       150       160       170       180     
pF1KE0 NLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHR
       .   :..  :.. : . ::::...:  .  . :.::::: ....::....:::: ...::
NP_002 D---GKHVYLVT-ELMRGGELLDKILRQ--KFFSEREASFVLHTIGKTVEYLHSQGVVHR
                  490       500         510       520       530    

         190       200        210       220        230       240   
pF1KE0 DVKPENLLYTSKRPNA-ILKLTDFGFAKETTSHNSLT-TPCYTPYYVAPEVLGPEKYDKS
       :.:: :.::...  :   :.. ::::::.  ..:.:  :::::  .::::::  . ::..
NP_002 DLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEG
          540       550       560       570       580       590    

           250       260       270        280       290       300  
pF1KE0 CDMWSLGVIMYILLCGYPPFYSNHGLAISPG-MKTRIRMGQYEFPNPEWSEVSEEVKMLI
       ::.::::...: .: :: ::   .: . .:  . :::  :.. . . .:. ::: .: :.
NP_002 CDIWSLGILLYTMLAGYTPF--ANGPSDTPEEILTRIGSGKFTLSGGNWNTVSETAKDLV
          600       610         620       630       640       650  

            310       320       330       340       350       360  
pF1KE0 RNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALAT
        ..:...: ::.:  . ..:::. :. :.::. :        ...  . ::  :... ..
NP_002 SKMLHVDPHQRLTAKQVLQHPWVTQKDKLPQSQL--------SHQDLQLVKGAMAATYSA
            660       670       680               690       700    

            370       380       390       400
pF1KE0 MRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH
       .  .    ..: ::..   .: .::  .: : ...:  
NP_002 LNSSKPTPQLKPIESS---ILAQRR--VRKLPSTTL  
          710       720            730       




400 residues in 1 query   sequences
64369986 residues in 92320 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Oct 24 21:37:19 2019 done: Thu Oct 24 21:37:19 2019
 Total Scan time:  4.760 Total Display time:  0.050

Function used was FASTA [36.3.4 Apr, 2011]
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