Result of FASTA (omim) for pF1KE2493
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE2493, 263 aa
  1>>>pF1KE2493 263 - 263 aa - 263 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.2438+/-0.000337; mu= 12.4326+/- 0.021
 mean_var=150.0131+/-29.647, 0's: 0 Z-trim(120.6): 91  B-trim: 0 in 0/51
 Lambda= 0.104715
 statistics sampled from 36018 (36125) to 36018 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.778), E-opt: 0.2 (0.424), width:  16
 Scan time:  5.870

The best scores are:                                      opt bits E(85289)
NP_001033722 (OMIM: 609595,610644) R-spondin-1 iso ( 263) 1898 297.8 1.4e-80
XP_006710646 (OMIM: 609595,610644) PREDICTED: R-sp ( 263) 1898 297.8 1.4e-80
NP_001229837 (OMIM: 609595,610644) R-spondin-1 iso ( 263) 1898 297.8 1.4e-80
NP_001229838 (OMIM: 609595,610644) R-spondin-1 iso ( 236) 1701 267.9 1.2e-71
NP_001229839 (OMIM: 609595,610644) R-spondin-1 iso ( 200) 1066 171.9 7.9e-43
NP_116173 (OMIM: 610574) R-spondin-3 precursor [Ho ( 272)  885 144.7 1.6e-34
XP_016866867 (OMIM: 610574) PREDICTED: R-spondin-3 ( 224)  840 137.8 1.6e-32
XP_016868884 (OMIM: 610575) PREDICTED: R-spondin-2 ( 242)  745 123.5 3.6e-28
NP_848660 (OMIM: 610575) R-spondin-2 isoform 1 pre ( 243)  744 123.4   4e-28
XP_011515321 (OMIM: 610575) PREDICTED: R-spondin-2 ( 249)  733 121.7 1.3e-27
XP_011515320 (OMIM: 610575) PREDICTED: R-spondin-2 ( 250)  732 121.6 1.4e-27
XP_016866868 (OMIM: 610574) PREDICTED: R-spondin-3 ( 203)  696 116.0 5.4e-26
NP_001025042 (OMIM: 206800,610573) R-spondin-4 iso ( 234)  652 109.5 5.9e-24
XP_016883328 (OMIM: 206800,610573) PREDICTED: R-sp ( 266)  629 106.0 7.1e-23
NP_001304871 (OMIM: 610575) R-spondin-2 isoform 3  ( 176)  610 103.0   4e-22
NP_001269792 (OMIM: 610575) R-spondin-2 isoform 2  ( 179)  475 82.6 5.5e-16
NP_001035096 (OMIM: 206800,610573) R-spondin-4 iso ( 172)  460 80.3 2.6e-15
XP_011517072 (OMIM: 600488) PREDICTED: proprotein  (1441)  255 50.4 2.2e-05
XP_016870289 (OMIM: 600488) PREDICTED: proprotein  (1450)  255 50.4 2.2e-05
XP_011517071 (OMIM: 600488) PREDICTED: proprotein  (1886)  255 50.5 2.6e-05
XP_005252096 (OMIM: 600488) PREDICTED: proprotein  (1887)  255 50.5 2.6e-05
NP_001177411 (OMIM: 600488) proprotein convertase  (1860)  254 50.4 2.9e-05
NP_001278238 (OMIM: 167405) proprotein convertase  ( 895)  232 46.7 0.00018
NP_612192 (OMIM: 167405) proprotein convertase sub ( 956)  232 46.7 0.00019
NP_002561 (OMIM: 167405) proprotein convertase sub ( 969)  232 46.7 0.00019
NP_006191 (OMIM: 600488) proprotein convertase sub ( 913)  222 45.2 0.00052


>>NP_001033722 (OMIM: 609595,610644) R-spondin-1 isoform  (263 aa)
 initn: 1898 init1: 1898 opt: 1898  Z-score: 1567.8  bits: 297.8 E(85289): 1.4e-80
Smith-Waterman score: 1898; 100.0% identity (100.0% similar) in 263 aa overlap (1-263:1-263)

               10        20        30        40        50        60
pF1KE2 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPKL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 HKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 HAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSR
              190       200       210       220       230       240

              250       260   
pF1KE2 RRKGQQQQQQQGTVGPLTSAGPA
       :::::::::::::::::::::::
NP_001 RRKGQQQQQQQGTVGPLTSAGPA
              250       260   

>>XP_006710646 (OMIM: 609595,610644) PREDICTED: R-spondi  (263 aa)
 initn: 1898 init1: 1898 opt: 1898  Z-score: 1567.8  bits: 297.8 E(85289): 1.4e-80
Smith-Waterman score: 1898; 100.0% identity (100.0% similar) in 263 aa overlap (1-263:1-263)

               10        20        30        40        50        60
pF1KE2 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPKL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 HKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 HAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSR
              190       200       210       220       230       240

              250       260   
pF1KE2 RRKGQQQQQQQGTVGPLTSAGPA
       :::::::::::::::::::::::
XP_006 RRKGQQQQQQQGTVGPLTSAGPA
              250       260   

>>NP_001229837 (OMIM: 609595,610644) R-spondin-1 isoform  (263 aa)
 initn: 1898 init1: 1898 opt: 1898  Z-score: 1567.8  bits: 297.8 E(85289): 1.4e-80
Smith-Waterman score: 1898; 100.0% identity (100.0% similar) in 263 aa overlap (1-263:1-263)

               10        20        30        40        50        60
pF1KE2 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPKL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 HKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 HAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSR
              190       200       210       220       230       240

              250       260   
pF1KE2 RRKGQQQQQQQGTVGPLTSAGPA
       :::::::::::::::::::::::
NP_001 RRKGQQQQQQQGTVGPLTSAGPA
              250       260   

>>NP_001229838 (OMIM: 609595,610644) R-spondin-1 isoform  (236 aa)
 initn: 1701 init1: 1701 opt: 1701  Z-score: 1407.5  bits: 267.9 E(85289): 1.2e-71
Smith-Waterman score: 1701; 99.6% identity (100.0% similar) in 233 aa overlap (31-263:4-236)

               10        20        30        40        50        60
pF1KE2 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPKL
                                     :.::::::::::::::::::::::::::::
NP_001                            MIFRVSAEGSQACAKGCELCSEVNGCLKCSPKL
                                          10        20        30   

               70        80        90       100       110       120
pF1KE2 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL
            40        50        60        70        80        90   

              130       140       150       160       170       180
pF1KE2 HKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVL
           100       110       120       130       140       150   

              190       200       210       220       230       240
pF1KE2 HAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSR
           160       170       180       190       200       210   

              250       260   
pF1KE2 RRKGQQQQQQQGTVGPLTSAGPA
       :::::::::::::::::::::::
NP_001 RRKGQQQQQQQGTVGPLTSAGPA
           220       230      

>>NP_001229839 (OMIM: 609595,610644) R-spondin-1 isoform  (200 aa)
 initn: 1109 init1: 1066 opt: 1066  Z-score: 889.9  bits: 171.9 E(85289): 7.9e-43
Smith-Waterman score: 1288; 76.0% identity (76.0% similar) in 263 aa overlap (1-263:1-200)

               10        20        30        40        50        60
pF1KE2 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPKL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 HKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVL
       :::::::::::::::::::::::::                                   
NP_001 HKGRCYPACPEGSSAANGTMECSSP-----------------------------------
              130       140                                        

              190       200       210       220       230       240
pF1KE2 HAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSR
                                   ::::::::::::::::::::::::::::::::
NP_001 ----------------------------GQKRRKGGQGRRENANRNLARKESKEAGAGSR
                                     150       160       170       

              250       260   
pF1KE2 RRKGQQQQQQQGTVGPLTSAGPA
       :::::::::::::::::::::::
NP_001 RRKGQQQQQQQGTVGPLTSAGPA
       180       190       200

>>NP_116173 (OMIM: 610574) R-spondin-3 precursor [Homo s  (272 aa)
 initn: 881 init1: 508 opt: 885  Z-score: 740.5  bits: 144.7 E(85289): 1.6e-34
Smith-Waterman score: 885; 46.0% identity (72.2% similar) in 252 aa overlap (10-251:11-257)

                10        20        30        40        50         
pF1KE2  MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPK
                 ..:.. .   :. . .:.::::.  . ::.:  ::  ::. ::::.:.:.
NP_116 MHLRLISWLFIILNFMEYIGSQNASRGRRQRRMHPNVSQGCQGGCATCSDYNGCLSCKPR
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KE2 LFILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLY
       ::. :::  ..:.:::: ::: ::. .: ::.::: ::: . :..::..::::::: :.:
NP_116 LFFALERIGMKQIGVCLSSCPSGYYGTRYPDINKCTKCKAD-CDTCFNKNFCTKCKSGFY
               70        80        90       100        110         

     120       130       140       150       160       170         
pF1KE2 LHKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRV
       :: :.:   ::::  : : :::: : ..::.:::.::.::.:: . :::.::.: :.:..
NP_116 LHLGKCLDNCPEGLEANNHTMECVSIVHCEVSEWNPWSPCTKKGKTCGFKRGTETRVREI
     120       130       140       150       160       170         

     180       190       200       210       220       230         
pF1KE2 LHAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGS
       .. : .    :  :.:::.:::.:  : .:.. .:: . .:.. :..    :::::   :
NP_116 IQHPSAKGNLCPPTNETRKCTVQRKKCQKGERGKKGRERKRKKPNKG----ESKEAIPDS
     180       190       200       210       220           230     

     240                 250       260      
pF1KE2 R----------RRKGQQQQQQQGTVGPLTSAGPA   
       .          .:...:::...               
NP_116 KSLESSKEIPEQRENKQQQKKRKVQDKQKSVSVSTVH
         240       250       260       270  

>>XP_016866867 (OMIM: 610574) PREDICTED: R-spondin-3 iso  (224 aa)
 initn: 847 init1: 480 opt: 840  Z-score: 704.8  bits: 137.8 E(85289): 1.6e-32
Smith-Waterman score: 840; 50.5% identity (75.5% similar) in 204 aa overlap (10-213:11-213)

                10        20        30        40        50         
pF1KE2  MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPK
                 ..:.. .   :. . .:.::::.  . ::.:  ::  ::. ::::.:.:.
XP_016 MHLRLISWLFIILNFMEYIGSQNASRGRRQRRMHPNVSQGCQGGCATCSDYNGCLSCKPR
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KE2 LFILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLY
       ::. :::  ..:.:::: ::: ::. .: ::.::: ::: . :..::..::::::: :.:
XP_016 LFFALERIGMKQIGVCLSSCPSGYYGTRYPDINKCTKCKAD-CDTCFNKNFCTKCKSGFY
               70        80        90       100        110         

     120       130       140       150       160       170         
pF1KE2 LHKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRV
       :: :.:   ::::  : : :::: : ..::.:::.::.::.:: . :::.::.: :.:..
XP_016 LHLGKCLDNCPEGLEANNHTMECVSIVHCEVSEWNPWSPCTKKGKTCGFKRGTETRVREI
     120       130       140       150       160       170         

     180       190       200       210       220       230         
pF1KE2 LHAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGS
       .. : .    :  :.:::.:::.:  : .:.. :                          
XP_016 IQHPSAKGNLCPPTNETRKCTVQRKKCQKGERGRTSRGDERCFNH               
     180       190       200       210       220                   

     240       250       260   
pF1KE2 RRRKGQQQQQQQGTVGPLTSAGPA

>>XP_016868884 (OMIM: 610575) PREDICTED: R-spondin-2 iso  (242 aa)
 initn: 735 init1: 497 opt: 745  Z-score: 626.8  bits: 123.5 E(85289): 3.6e-28
Smith-Waterman score: 745; 41.5% identity (67.9% similar) in 234 aa overlap (1-234:1-230)

               10        20        30        40        50        60
pF1KE2 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPKL
       :.. :   ::..         .: . .:..: :  ..  : :::  ::. ::: .:. ::
XP_016 MQFRLFSFALIILNCMDYSHCQGNRWRRSKRASYVSNPIC-KGCLSCSKDNGCSRCQQKL
               10        20        30        40         50         

               70        80        90       100       110       120
pF1KE2 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL
       :..:.:. .:: : :: ::: ::.  : ::::.: .:.::.:..:::..:::::: :.::
XP_016 FFFLRREGMRQYGECLHSCPSGYYGHRAPDMNRCARCRIENCDSCFSKDFCTKCKVGFYL
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KE2 HKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVL
       :.:::.  ::.: .  . ::::   . ::...:: :: ::.... :::. : : :::...
XP_016 HRGRCFDECPDGFAPLEETMEC---VGCEVGHWSEWGTCSRNNRTCGFKWGLETRTRQIV
     120       130       140          150       160       170      

              190       200       210       220       230       240
pF1KE2 HAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSR
       . :: :   :    :.::: .    :: :..  :. . : .. .:.: .. ...      
XP_016 KKPVKDTILCPTIAESRRCKMTMRHCPGGKRTPKAKEKRNKKKKRKLIERAQEQHSVFLA
        180       190       200       210       220       230      

              250       260   
pF1KE2 RRKGQQQQQQQGTVGPLTSAGPA
                              
XP_016 TDRANQ                 
        240                   

>>NP_848660 (OMIM: 610575) R-spondin-2 isoform 1 precurs  (243 aa)
 initn: 723 init1: 485 opt: 744  Z-score: 626.0  bits: 123.4 E(85289): 4e-28
Smith-Waterman score: 744; 41.5% identity (67.5% similar) in 234 aa overlap (1-234:1-231)

               10        20        30        40        50        60
pF1KE2 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPKL
       :.. :   ::..         .: . .:..: :  ..  : :::  ::. ::: .:. ::
NP_848 MQFRLFSFALIILNCMDYSHCQGNRWRRSKRASYVSNPIC-KGCLSCSKDNGCSRCQQKL
               10        20        30        40         50         

               70        80        90       100       110       120
pF1KE2 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL
       :..:.:. .:: : :: ::: ::.  : ::::.: .:.::.:..:::..:::::: :.::
NP_848 FFFLRREGMRQYGECLHSCPSGYYGHRAPDMNRCARCRIENCDSCFSKDFCTKCKVGFYL
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KE2 HKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVL
       :.:::.  ::.: .  . ::::     ::...:: :: ::.... :::. : : :::...
NP_848 HRGRCFDECPDGFAPLEETMECVE--GCEVGHWSEWGTCSRNNRTCGFKWGLETRTRQIV
     120       130       140         150       160       170       

              190       200       210       220       230       240
pF1KE2 HAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSR
       . :: :   :    :.::: .    :: :..  :. . : .. .:.: .. ...      
NP_848 KKPVKDTILCPTIAESRRCKMTMRHCPGGKRTPKAKEKRNKKKKRKLIERAQEQHSVFLA
       180       190       200       210       220       230       

              250       260   
pF1KE2 RRKGQQQQQQQGTVGPLTSAGPA
                              
NP_848 TDRANQ                 
       240                    

>>XP_011515321 (OMIM: 610575) PREDICTED: R-spondin-2 iso  (249 aa)
 initn: 735 init1: 497 opt: 733  Z-score: 616.9  bits: 121.7 E(85289): 1.3e-27
Smith-Waterman score: 733; 41.3% identity (68.6% similar) in 242 aa overlap (1-234:1-237)

               10            20        30            40        50  
pF1KE2 MRLGLCVVALV----LSWTHLTISSRGIKGKRQRRISAEGSQA----CAKGCELCSEVNG
       :.. :   ::.    ....:   ..:  ..::   .::..: .    : :::  ::. ::
XP_011 MQFRLFSFALIILNCMDYSHCQ-GNRWRRSKRGGSLSAKASYVSNPIC-KGCLSCSKDNG
               10        20         30        40         50        

             60        70        80        90       100       110  
pF1KE2 CLKCSPKLFILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCT
       : .:. :::..:.:. .:: : :: ::: ::.  : ::::.: .:.::.:..:::..:::
XP_011 CSRCQQKLFFFLRREGMRQYGECLHSCPSGYYGHRAPDMNRCARCRIENCDSCFSKDFCT
       60        70        80        90       100       110        

            120       130       140       150       160       170  
pF1KE2 KCKEGLYLHKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGS
       ::: :.:::.:::.  ::.: .  . ::::   . ::...:: :: ::.... :::. : 
XP_011 KCKVGFYLHRGRCFDECPDGFAPLEETMEC---VGCEVGHWSEWGTCSRNNRTCGFKWGL
      120       130       140          150       160       170     

            180       190       200       210       220       230  
pF1KE2 EERTRRVLHAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKES
       : :::.... :: :   :    :.::: .    :: :..  :. . : .. .:.: .. .
XP_011 ETRTRQIVKKPVKDTILCPTIAESRRCKMTMRHCPGGKRTPKAKEKRNKKKKRKLIERAQ
         180       190       200       210       220       230     

            240       250       260   
pF1KE2 KEAGAGSRRRKGQQQQQQQGTVGPLTSAGPA
       ..                             
XP_011 EQHSVFLATDRANQ                 
         240                          




263 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon Nov  7 20:58:32 2016 done: Mon Nov  7 20:58:32 2016
 Total Scan time:  5.870 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
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