Result of FASTA (ccds) for pF1KE2603
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE2603, 979 aa
  1>>>pF1KE2603 979 - 979 aa - 979 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 11.8104+/-0.00121; mu= -8.5194+/- 0.073
 mean_var=315.1759+/-64.410, 0's: 0 Z-trim(111.2): 71  B-trim: 0 in 0/51
 Lambda= 0.072243
 statistics sampled from 12145 (12194) to 12145 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.685), E-opt: 0.2 (0.375), width:  16
 Scan time:  3.270

The best scores are:                                      opt bits E(32554)
CCDS46818.1 MAP4 gene_id:4134|Hs108|chr3           (1135) 3736 403.9 9.1e-112
CCDS33750.1 MAP4 gene_id:4134|Hs108|chr3           (1152) 3736 404.0 9.2e-112
CCDS46821.1 MAP4 gene_id:4134|Hs108|chr3           (  99)  622 78.9 5.7e-15
CCDS11501.1 MAPT gene_id:4137|Hs108|chr17          ( 758)  607 77.7 9.6e-14
CCDS45715.1 MAPT gene_id:4137|Hs108|chr17          ( 776)  582 75.1 5.9e-13
CCDS33369.1 MAP2 gene_id:4133|Hs108|chr2           ( 559)  575 74.3 7.4e-13
CCDS11499.1 MAPT gene_id:4137|Hs108|chr17          ( 441)  570 73.8 8.7e-13
CCDS45716.1 MAPT gene_id:4137|Hs108|chr17          ( 412)  555 72.2 2.4e-12
CCDS11500.1 MAPT gene_id:4137|Hs108|chr17          ( 383)  543 70.9 5.4e-12


>>CCDS46818.1 MAP4 gene_id:4134|Hs108|chr3                (1135 aa)
 initn: 5863 init1: 3590 opt: 3736  Z-score: 2120.1  bits: 403.9 E(32554): 9.1e-112
Smith-Waterman score: 4991; 82.9% identity (82.9% similar) in 1011 aa overlap (1-838:1-1011)

               10        20        30        40        50        60
pF1KE2 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE2 KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE2 ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE2 LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM
              490       500       510       520       530       540

              550                                                  
pF1KE2 EVALTEDQVPALKTEAP-------------------------------------------
       :::::::::::::::::                                           
CCDS46 EVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKG
              550       560       570       580       590       600

                                                                   
pF1KE2 ------------------------------------------------------------
                                                                   
CCDS46 ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSE
              610       620       630       640       650       660

                                                                   
pF1KE2 ------------------------------------------------------------
                                                                   
CCDS46 LSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQ
              670       680       690       700       710       720

                 560       570       580       590       600       
pF1KE2 ----------TTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK
                 ::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 PTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK
              730       740       750       760       770       780

       610       620       630       640       650       660       
pF1KE2 APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE
              790       800       810       820       830       840

       670       680       690       700       710       720       
pF1KE2 GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST
              850       860       870       880       890       900

       730       740       750       760       770       780       
pF1KE2 TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKT
              910       920       930       940       950       960

       790       800       810       820       830       840       
pF1KE2 EAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGG
       :::::::::::::::::::::::::::::::::::::::::::::::::::         
CCDS46 EAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGG
              970       980       990      1000      1010      1020

       850       860       870       880       890       900       
pF1KE2 GNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL
                                                                   
CCDS46 GNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL
             1030      1040      1050      1060      1070      1080

>>CCDS33750.1 MAP4 gene_id:4134|Hs108|chr3                (1152 aa)
 initn: 3590 init1: 3590 opt: 3736  Z-score: 2120.0  bits: 404.0 E(32554): 9.2e-112
Smith-Waterman score: 4991; 82.9% identity (82.9% similar) in 1011 aa overlap (1-838:1-1011)

               10        20        30        40        50        60
pF1KE2 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE2 KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE2 ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE2 LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM
              490       500       510       520       530       540

              550                                                  
pF1KE2 EVALTEDQVPALKTEAP-------------------------------------------
       :::::::::::::::::                                           
CCDS33 EVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKG
              550       560       570       580       590       600

                                                                   
pF1KE2 ------------------------------------------------------------
                                                                   
CCDS33 ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSE
              610       620       630       640       650       660

                                                                   
pF1KE2 ------------------------------------------------------------
                                                                   
CCDS33 LSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQ
              670       680       690       700       710       720

                 560       570       580       590       600       
pF1KE2 ----------TTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK
                 ::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 PTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK
              730       740       750       760       770       780

       610       620       630       640       650       660       
pF1KE2 APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE
              790       800       810       820       830       840

       670       680       690       700       710       720       
pF1KE2 GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST
              850       860       870       880       890       900

       730       740       750       760       770       780       
pF1KE2 TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKT
              910       920       930       940       950       960

       790       800       810       820       830       840       
pF1KE2 EAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGG
       :::::::::::::::::::::::::::::::::::::::::::::::::::         
CCDS33 EAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGG
              970       980       990      1000      1010      1020

       850       860       870       880       890       900       
pF1KE2 GNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL
                                                                   
CCDS33 GNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL
             1030      1040      1050      1060      1070      1080

>--
 initn: 939 init1: 939 opt: 939  Z-score: 544.5  bits: 112.4 E(32554): 5.2e-24
Smith-Waterman score: 939; 100.0% identity (100.0% similar) in 141 aa overlap (839-979:1012-1152)

      810       820       830       840       850       860        
pF1KE2 ASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGS
                                     ::::::::::::::::::::::::::::::
CCDS33 ASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGS
             990      1000      1010      1020      1030      1040 

      870       880       890       900       910       920        
pF1KE2 KANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 KANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGP
            1050      1060      1070      1080      1090      1100 

      930       940       950       960       970         
pF1KE2 PAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETSI
       :::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 PAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETSI
            1110      1120      1130      1140      1150  

>>CCDS46821.1 MAP4 gene_id:4134|Hs108|chr3                (99 aa)
 initn: 622 init1: 622 opt: 622  Z-score: 382.2  bits: 78.9 E(32554): 5.7e-15
Smith-Waterman score: 622; 100.0% identity (100.0% similar) in 97 aa overlap (1-97:1-97)

               10        20        30        40        50        60
pF1KE2 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP
       :::::::::::::::::::::::::::::::::::::                       
CCDS46 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTEA                     
               70        80        90                              

              130       140       150       160       170       180
pF1KE2 EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP

>>CCDS11501.1 MAPT gene_id:4137|Hs108|chr17               (758 aa)
 initn: 477 init1: 477 opt: 607  Z-score: 360.3  bits: 77.7 E(32554): 9.6e-14
Smith-Waterman score: 673; 31.5% identity (54.1% similar) in 604 aa overlap (337-916:163-689)

        310       320       330       340       350         360    
pF1KE2 ELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASP--IKMDL
                                     : :.   :.       :  : .:  .: .:
CCDS11 QEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQL
            140       150       160       170       180       190  

           370       380        390       400          410         
pF1KE2 APS-KDMGPPKENKKETER-ASPIKMDLAPSKDMGPPKEN---KIVPAKDLVLLSEIEVA
         . .. ::: ..    :: .:  ..:   . : . :...   :  ::.:        .:
CCDS11 LGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDG--RPPQTAA
            200       210       220       230       240         250

     420       430       440       450       460           470     
pF1KE2 QANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLE----AEVAPV
       .    : .    .:  . ..  ..:.     . :   .:  .: .  :::    .:..: 
CCDS11 REATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPN
              260       270       280       290       300       310

           480       490       500       510       520       530   
pF1KE2 --KDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLI--
         :..:.  :     :   ::.   :.   .  :   .:. :   :.  : : . .    
CCDS11 VQKEQAHSEEHLGRAAFPGAPGEGPEA---RGPSLGEDTKEA---DLPEPSEKQPAAAPR
              320       330          340          350       360    

              540          550       560       570       580       
pF1KE2 -KNVCLPPEME---VALTEDQVPALKTEAPTTIGGLNKKPMSLASGLVPAAPPKRPAVAS
        : :   :...   :. ..: . .   .: :.  .  :   .: .   :   ::.:. .:
CCDS11 GKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAK---TLKNR--PCLSPKHPTPGS
          370       380       390       400            410         

       590       600       610       620       630       640       
pF1KE2 ARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTG
       . : : ::   .:     :  ::  .:: : .:. .::.::.... .    . . .  . 
CCDS11 SDPLIQPS---SP-----AVCPEPPSSP-KYVSSVTSRTGSSGAKEMKLKGADGKTKIAT
     420               430        440       450       460       470

       650       660       670       680       690       700       
pF1KE2 PSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSG-TA
       : . .:    : .      .:. :.. .. ::. ::  . :   :..   :.   :: ..
CCDS11 PRGAAP----PGQ------KGQ-ANATRIPAKTPPAPKTPP---SSGEPPKSGDRSGYSS
                        480        490       500          510      

        710        720       730         740       750        760  
pF1KE2 PAAGVVP-SRVKATPMPSRPSTTPFIDKKPTSAK--PSSTTPRLSRLATN-TSAPDLKNV
       :..  .: :: ..  .:. :.  :   :: . ..  :.: .   ::: :  .  ::::::
CCDS11 PGSPGTPGSRSRTPSLPTPPTREP---KKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNV
        520       530       540          550       560       570   

            770       780       790       800       810       820  
pF1KE2 RSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIV
       .::.:::::.:::::::                                      ::::.
CCDS11 KSKIGSTENLKHQPGGG--------------------------------------KVQII
           580       590                                           

            830       840       850       860       870       880  
pF1KE2 SKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVK
       .::.. :..:::::::::::::::::.:::  : ::.:::.::::: .::.::::::.:.
CCDS11 NKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVE
         600       610       620       630       640       650     

            890       900       910       920       930       940  
pF1KE2 IESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPE
       ..:.::.::...:.:.:::::. :.:.::  : :                          
CCDS11 VKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPV
         660       670       680       690       700       710     

            950       960       970               
pF1KE2 AGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETSI      
                                                  
CCDS11 VSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
         720       730       740       750        

>>CCDS45715.1 MAPT gene_id:4137|Hs108|chr17               (776 aa)
 initn: 477 init1: 477 opt: 582  Z-score: 346.0  bits: 75.1 E(32554): 5.9e-13
Smith-Waterman score: 696; 31.5% identity (54.6% similar) in 606 aa overlap (337-916:163-707)

        310       320       330       340       350         360    
pF1KE2 ELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASP--IKMDL
                                     : :.   :.       :  : .:  .: .:
CCDS45 QEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQL
            140       150       160       170       180       190  

           370       380        390       400          410         
pF1KE2 APS-KDMGPPKENKKETER-ASPIKMDLAPSKDMGPPKEN---KIVPAKDLVLLSEIEVA
         . .. ::: ..    :: .:  ..:   . : . :...   :  ::.:        .:
CCDS45 LGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDG--RPPQTAA
            200       210       220       230       240         250

     420       430       440       450       460           470     
pF1KE2 QANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLE----AEVAPV
       .    : .    .:  . ..  ..:.     . :   .:  .: .  :::    .:..: 
CCDS45 REATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPN
              260       270       280       290       300       310

           480       490       500       510       520       530   
pF1KE2 --KDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLI--
         :..:.  :     :   ::.   :.   .  :   .:. :   :.  : : . .    
CCDS45 VQKEQAHSEEHLGRAAFPGAPGEGPEA---RGPSLGEDTKEA---DLPEPSEKQPAAAPR
              320       330          340          350       360    

              540          550       560       570       580       
pF1KE2 -KNVCLPPEME---VALTEDQVPALKTEAPTTIGGLNKKPMSLASGLVPAAPPKRPAVAS
        : :   :...   :. ..: . .   .: :.  .  :   .: .   :   ::.:. .:
CCDS45 GKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAK---TLKNR--PCLSPKHPTPGS
          370       380       390       400            410         

       590        600       610        620       630       640     
pF1KE2 ARPSILPSKD-VKPKPIADAKAPEKRAS-PSKPASAPASRSGSKSTQTVAKTTTAAAVAS
       . : : ::.  : :.:    ..:.  .:  :. .:. :..   :...  .: .:  ..: 
CCDS45 SDPLIQPSSPAVCPEP---PSSPKYVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAP
     420       430          440       450       460       470      

         650       660        670       680       690       700    
pF1KE2 TGPSSRSPSTLLPKK-PTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSG
        : .... .: .: : : : ::  . : .:..  .  ::    :.:      :.    . 
CCDS45 PGQKGQANATRIPAKTPPAPKTPPSSA-TKQVQRRPPPAG---PRSERGEPPKSGDRSGY
        480       490       500        510          520       530  

          710        720       730         740       750        760
pF1KE2 TAPAAGVVP-SRVKATPMPSRPSTTPFIDKKPTSAK--PSSTTPRLSRLATN-TSAPDLK
       ..:..  .: :: ..  .:. :.  :   :: . ..  :.: .   ::: :  .  ::::
CCDS45 SSPGSPGTPGSRSRTPSLPTPPTREP---KKVAVVRTPPKSPSSAKSRLQTAPVPMPDLK
            540       550          560       570       580         

              770       780       790       800       810       820
pF1KE2 NVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQ
       ::.::.:::::.:::::::                                      :::
CCDS45 NVKSKIGSTENLKHQPGGG--------------------------------------KVQ
     590       600                                             610 

              830       840       850       860       870       880
pF1KE2 IVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGD
       :..::.. :..:::::::::::::::::.:::  : ::.:::.::::: .::.::::::.
CCDS45 IINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQ
             620       630       640       650       660       670 

              890       900       910       920       930       940
pF1KE2 VKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAA
       :...:.::.::...:.:.:::::. :.:.::  : :                        
CCDS45 VEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKS
             680       690       700       710       720       730 

              950       960       970               
pF1KE2 PEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETSI      
                                                    
CCDS45 PVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
             740       750       760       770      

>>CCDS33369.1 MAP2 gene_id:4133|Hs108|chr2                (559 aa)
 initn: 892 init1: 455 opt: 575  Z-score: 344.3  bits: 74.3 E(32554): 7.4e-13
Smith-Waterman score: 627; 34.1% identity (55.5% similar) in 425 aa overlap (508-916:124-490)

       480       490       500       510       520         530     
pF1KE2 MAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPP-PETE-VVLIKNVC
                                     ::.  : :      :: : .: .: .... 
CCDS33 IVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPSPASEQTVTVEEAA
           100       110       120       130       140       150   

              540       550       560       570       580          
pF1KE2 -----LPPEMEVALTEDQVPALKTEAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASA--
            : : .    ..:.:         .. : .:.:    :.  :..  :: . ...  
CCDS33 GGESALAPSV-FKQAKDKVSNSTLSKIPALQGSTKSPR--YSSACPSTT-KRATFSDSLL
           160        170       180       190          200         

       590       600            610       620       630       640  
pF1KE2 -RPSILPSKDVKPKPIAD-----AKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAA
        .:.   : :  :   .      .:.::::.:  .:.:    : : .. .   . .  ..
CCDS33 IQPTSAGSTDRLPYSKSGNKDGVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLNSS
     210       220       230       240       250       260         

            650       660       670       680        690       700 
pF1KE2 VASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSR-PKSTSTSSMKKTTT
       ..:..  .     .     .. .:   :. .  .:  . :.  :: : . .: :. .:  
CCDS33 ISSSARRTTRSEPIRRAGKSGTSTPTTPGSTA-ITPGTPPSYSSRTPGTPGTPSYPRTPH
     270       280       290       300        310       320        

             710       720       730       740       750       760 
pF1KE2 LSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKN
         ::  .: .:::. :.. . . :       :.:.       ::.  ::  :   :::::
CCDS33 TPGTPKSAILVPSEKKVAIIRTPP-------KSPA-------TPKQLRLI-NQPLPDLKN
      330       340       350                     360        370   

             770       780       790       800       810       820 
pF1KE2 VRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQI
       :.::.:::.:::.:: ::                                      .:.:
CCDS33 VKSKIGSTDNIKYQPKGG--------------------------------------QVRI
           380       390                                           

             830       840       850       860       870       880 
pF1KE2 VSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDV
       ..::...:..::.:::::::::  ::::::: .::.:.:.:.:::::  ::.:.:::: :
CCDS33 LNKKIDFSKVQSRCGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRV
         400       410       420       430       440       450     

             890       900       910       920       930       940 
pF1KE2 KIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAP
       :::: ::.::::::::::::::. :.:.:: :: .                         
CCDS33 KIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSP
         460       470       480       490       500       510     

             950       960       970               
pF1KE2 EAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETSI      
                                                   
CCDS33 GRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL
         520       530       540       550         

>>CCDS11499.1 MAPT gene_id:4137|Hs108|chr17               (441 aa)
 initn: 477 init1: 477 opt: 570  Z-score: 343.0  bits: 73.8 E(32554): 8.7e-13
Smith-Waterman score: 640; 36.1% identity (59.9% similar) in 379 aa overlap (559-916:39-372)

      530       540       550       560       570       580        
pF1KE2 VLIKNVCLPPEMEVALTEDQVPALKTEAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASA
                                     : .::...:..  .      : .. . :..
CCDS11 EVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKS
       10        20        30        40        50        60        

      590       600       610           620       630           640
pF1KE2 RPSILPSKDVKPKPIADAKAPEKRASPSK----PASAPASRSGSKSTQTV----AKTTTA
        :.   ..::   :..:  :: :.:. .     : .. : ..:  .: ..    :  .: 
CCDS11 TPT---AEDVTA-PLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQ
       70            80        90       100       110       120    

                   650       660        670       680        690   
pF1KE2 AAVAS-----TGPSSRSPSTLLPKKPTAI-KTEGKPAEVKKMTAKSVPADLS-RPKSTST
       : ..:     :: .... .    :   :  .  . :..  . .:  .::     ::.  .
CCDS11 ARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPS
          130       140       150       160       170       180    

            700        710        720       730         740        
pF1KE2 SSMK-KTTTLSG-TAPAAGVVP-SRVKATPMPSRPSTTPFIDKKPTSAK--PSSTTPRLS
       :.   :.   :: ..:..  .: :: ..  .:. :.  :   :: . ..  :.: .   :
CCDS11 SGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREP---KKVAVVRTPPKSPSSAKS
          190       200       210       220          230       240 

      750        760       770       780       790       800       
pF1KE2 RLATN-TSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGP
       :: :  .  ::::::.::.:::::.:::::::                            
CCDS11 RLQTAPVPMPDLKNVKSKIGSTENLKHQPGGG----------------------------
             250       260       270                               

       810       820       830       840       850       860       
pF1KE2 IASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCG
                 ::::..::.. :..:::::::::::::::::.:::  : ::.:::.::::
CCDS11 ----------KVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCG
                     280       290       300       310       320   

       870       880       890       900       910       920       
pF1KE2 SKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPG
       : .::.::::::.:...:.::.::...:.:.:::::. :.:.::  : :           
CCDS11 SLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAK
           330       340       350       360       370       380   

       930       940       950       960       970               
pF1KE2 PPAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETSI      
                                                                 
CCDS11 AKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
           390       400       410       420       430       440 

>>CCDS45716.1 MAPT gene_id:4137|Hs108|chr17               (412 aa)
 initn: 477 init1: 477 opt: 555  Z-score: 335.0  bits: 72.2 E(32554): 2.4e-12
Smith-Waterman score: 635; 33.7% identity (58.5% similar) in 386 aa overlap (538-916:4-343)

       510       520       530       540       550       560       
pF1KE2 PLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPTTIGG--LNK
                                     :..:  . ::.. .         ::  ...
CCDS45                            MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQ
                                          10        20        30   

         570       580       590       600       610       620     
pF1KE2 KPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASR
          . ... .  .: . :.  ...     ..:.:  : :.:.      .::    : .  
CCDS45 DQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHV
            40        50        60        70        80        90   

         630       640       650       660       670       680     
pF1KE2 SGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADL
       . .. ..     : .    . : .... .   :.  .    .:. :.. .. ::. ::  
CCDS45 TQARMVSKSKDGTGSDDKKAKGADGKT-KIATPRGAAPPGQKGQ-ANATRIPAKTPPAPK
           100       110       120        130        140       150 

         690       700        710        720       730         740 
pF1KE2 SRPKSTSTSSMKKTTTLSG-TAPAAGVVP-SRVKATPMPSRPSTTPFIDKKPTSAK--PS
       . :   :..   :.   :: ..:..  .: :: ..  .:. :.  :   :: . ..  :.
CCDS45 TPP---SSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREP---KKVAVVRTPPK
                160       170       180       190          200     

             750        760       770       780       790       800
pF1KE2 STTPRLSRLATN-TSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNA
       : .   ::: :  .  ::::::.::.:::::.:::::::                     
CCDS45 SPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGG---------------------
         210       220       230       240                         

              810       820       830       840       850       860
pF1KE2 VTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDIS
                        ::::..::.. :..:::::::::::::::::.:::  : ::.:
CCDS45 -----------------KVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLS
                           250       260       270       280       

              870       880       890       900       910       920
pF1KE2 KVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGS
       ::.::::: .::.::::::.:...:.::.::...:.:.:::::. :.:.::  : :    
CCDS45 KVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKL
       290       300       310       320       330       340       

              930       940       950       960       970          
pF1KE2 EAPLCPGPPAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETSI 
                                                                   
CCDS45 TFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASL
       350       360       370       380       390       400       

>>CCDS11500.1 MAPT gene_id:4137|Hs108|chr17               (383 aa)
 initn: 477 init1: 477 opt: 543  Z-score: 328.7  bits: 70.9 E(32554): 5.4e-12
Smith-Waterman score: 606; 42.4% identity (64.0% similar) in 264 aa overlap (658-916:96-314)

       630       640       650       660       670       680       
pF1KE2 SKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSR
                                     :.  .    .:. :.. .. ::. ::  . 
CCDS11 QARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQ-ANATRIPAKTPPAPKTP
          70        80        90       100        110       120    

       690       700        710        720       730         740   
pF1KE2 PKSTSTSSMKKTTTLSG-TAPAAGVVP-SRVKATPMPSRPSTTPFIDKKPTSAK--PSST
       :   :..   :.   :: ..:..  .: :: ..  .:. :.  :   :: . ..  :.: 
CCDS11 P---SSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREP---KKVAVVRTPPKSP
             130       140       150       160          170        

           750        760       770       780       790       800  
pF1KE2 TPRLSRLATN-TSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVT
       .   ::: :  .  ::::::.::.:::::.:::::::                       
CCDS11 SSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGG-----------------------
      180       190       200       210                            

            810       820       830       840       850       860  
pF1KE2 KTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKV
                      ::::..::.. :..:::::::::::::::::.:::  : ::.:::
CCDS11 ---------------KVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKV
                        220       230       240       250       260

            870       880       890       900       910       920  
pF1KE2 SSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEA
       .::::: .::.::::::.:...:.::.::...:.:.:::::. :.:.::  : :      
CCDS11 TSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTF
              270       280       290       300       310       320

            930       940       950       960       970            
pF1KE2 PLCPGPPAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETSI   
                                                                   
CCDS11 RENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAK
              330       340       350       360       370       380




979 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Nov  8 16:59:30 2016 done: Tue Nov  8 16:59:31 2016
 Total Scan time:  3.270 Total Display time:  0.120

Function used was FASTA [36.3.4 Apr, 2011]
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